2,833 results match your criteria Toxicity Toluene


Environmental Aspects of the Use of Extract in Bioremediation Process.

Microorganisms 2019 Feb 5;7(2). Epub 2019 Feb 5.

Institute of Chemical Technology and Engineering, Poznan University of Technology, Berdychowo 4, 60-965 Poznan, Poland.

This paper analyzes the impact of saponins from English ivy leaves on the properties of environmental bacterial strains and hydrocarbon degradation ability. For this purpose, two bacterial strains, M03 and M1B, have been used in toluene, 4-chlorotoluene, and α,α,α-trifluorotoluene biodegradation supported by extract. Moreover, theeffects of ivy exposition on cell properties and extract toxicity were investigated. Read More

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http://www.mdpi.com/2076-2607/7/2/43
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http://dx.doi.org/10.3390/microorganisms7020043DOI Listing
February 2019
1 Read

Toxic by design? Formation of thermal degradants and cyanide from carboxamide-type synthetic cannabinoids CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18 during exposure to high temperatures.

Forensic Toxicol 2019 Jan 28;37(1):17-26. Epub 2018 Jun 28.

RTI International, 3040 Cornwallis Road, Research Triangle Park, NC, 27709, USA.

Purpose: The use of novel synthetic cannabinoids as intoxicants continues in spite of associated health risks. These compounds are typically smoked or vaporized, but many synthetic cannabinoids contain thermally labile chemical moieties. This study investigated the thermal stability six carboxamide-type synthetic cannabinoids (CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18) in order to characterise potential user exposure to thermolysis products. Read More

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http://dx.doi.org/10.1007/s11419-018-0430-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349387PMC
January 2019
1 Read

Assessment of benzene, toluene, ethyl-benzene, and xylene (BTEX) toxicity in soil using sulfur-oxidizing bacterial (SOB) bioassay.

Chemosphere 2019 Apr 17;220:651-657. Epub 2018 Dec 17.

Department of Biological Environment, Kangwon National University, Chuncheon, 24341, Gangwon-do, South Korea. Electronic address:

The assessment of benzene, toluene, ethyl-benzene, and xylene (BTEX)-contaminated soil toxicity was performed using a sulfur-oxidizing bacteria (SOB) assay. The experiments were set up using an individual pollutant in a 25-mL bottle sealed with a rubber stopper and aluminum cap since BTEX are volatile. A large headspace volume (14 mL) was kept in the reactors to provide enough oxygen for the SOB. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2018.12.102DOI Listing
April 2019
2 Reads

Toxicity and expression of oxidative stress genes in Tribolium castaneum induced by toluene, xylene, and thinner.

J Toxicol Environ Health A 2018 Dec 24:1-9. Epub 2018 Dec 24.

a Environmental and Computational Chemistry Group. School of Pharmaceutical Sciences , Zaragocilla Campus. University of Cartagena , Cartagena, Bolivar , Colombia.

Thinner is a solvent that contains toluene, xylene, and other substances. The aim of this study was to examine the toxicity of thinner, xylene, and toluene on adult red flour beetles, Tribolium castaneum (Herbst), as well as the effects of thinner and toluene on gene expression. The major compounds identified in the thinner with peak area >2% were p-xylene (6%), toluene (4%), 2,4-dimethylheptane (3%), methylcyclohexane (2. Read More

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https://www.tandfonline.com/doi/full/10.1080/15287394.2018.1
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http://dx.doi.org/10.1080/15287394.2018.1546245DOI Listing
December 2018
7 Reads

Pulsed laser assisted synthesis of gadolinium carbide/carbon shell dots with enhanced magnetic resonance properties.

Nanotechnology 2019 Mar 6;30(10):105705. Epub 2018 Dec 6.

School of Materials Science and Engineering, Hefei University of Technology, Anhui 230009, People's Republic of China. State Key Laboratory of Pulsed Power Laser Technology, Electronic Engineering Institute, Anhui 230037, People's Republic of China.

There is now the opportunity for nanomaterials to be utilized in bioapplications with low toxicity, good stability and fine dissolvability. Herein, we present a pulsed laser assisted carbon coating method for nanocrystals, and gadolinium carbide/carbon shell (GC/CS) dots with a face-centered cubic structured gadolinium carbide core that have been synthesized in toluene. Good stability of the GC/CS dots was observed, not only in ethanol but also in the immunoconjugates. Read More

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http://iopscience.iop.org/article/10.1088/1361-6528/aaf6c5
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http://dx.doi.org/10.1088/1361-6528/aaf6c5DOI Listing
March 2019
6 Reads

Successful resuscitation of prolonged cardiac arrest occurring in association with '' and toluene toxicity.

Turk J Emerg Med 2018 Dec 7;18(4):172-175. Epub 2018 Mar 7.

Karadeniz Technical University, Faculty of Medicine, Department of Cardiology, Trabzon, Turkey.

We report a case of prolonged and successful resuscitation following cardiotoxicity-related arrest occurring after inhaling toluene and , which is an increasingly popular synthetic cannabinoid (SC). Following presentation to the emergency department because of lethargy, nausea and chest pain, a 28-year-old male user of and toluene suffered from cardiac arrest due to ventricular fibrillation (VF). Cardiogenic shock, severe metabolic acidosis and regular wide QRS tachycardia were observed in the patient, and he developed VF every 5-10 minutes over the course of 10 hours. Read More

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http://dx.doi.org/10.1016/j.tjem.2018.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261096PMC
December 2018
3 Reads

Pharmacokinetics and brain distribution of amitraz and its metabolites in rats.

Environ Toxicol Pharmacol 2019 Jan 23;65:40-45. Epub 2018 Nov 23.

Zoetis, Inc., Veterinary Medicine Research and Development, Kalamazoo, MI, 49007, USA.

Amitraz is an acaricide and insecticide widely used in agriculture and veterinary medicine. Although central nervous system (CNS) toxicity is one of major toxicities following oral ingestion of amitraz, the understanding of the cause of the toxicity is limited. This study evaluated the systemic and brain exposure of amitraz and its major metabolites, BTS27271, 2',4'-formoxylidide, and 2,4-dimethylaniline following administration of amitraz in male Sprague-Dawley rats. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13826689183047
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http://dx.doi.org/10.1016/j.etap.2018.11.005DOI Listing
January 2019
2 Reads

Evaluation of Three Peptide Immobilization Techniques on a QCM Surface Related to Acetaldehyde Responses in the Gas Phase.

Sensors (Basel) 2018 Nov 14;18(11). Epub 2018 Nov 14.

Department of Analytical Chemistry, Chemical Faculty, Gdańsk University of Technology, Gabriela Narutowicza 11/12, 80-233 Gdansk, Poland.

The quartz-crystal microbalance is a sensitive and universal tool for measuring concentrations of various gases in the air. Biochemical functionalization of the QCM electrode allows a label-free detection of specific molecular interactions with high sensitivity and specificity. In addition, it enables a real-time determination of its kinetic rates and affinity constants. Read More

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http://dx.doi.org/10.3390/s18113942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264005PMC
November 2018
1 Read

The efficacy and cytotoxicity of iron oxide-carbon black composites for liquid-phase toluene oxidation by persulfate.

Environ Sci Pollut Res Int 2018 Nov 1. Epub 2018 Nov 1.

Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan.

This study evaluated the oxidation of toluene (TOL) by persulfate (PS) in aqueous solution in the presence of a FeO-carbon black (CB) composite oxidant system generating sulfate radicals. The cytotoxic activity and oxidative stress generated by these materials were investigated in rat liver Clone 9 cells. The effects of various operating parameters including the pH and concentrations of PS, FeO-CB, and TOL were evaluated to optimize the oxidation process. Read More

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http://link.springer.com/10.1007/s11356-018-3593-7
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http://dx.doi.org/10.1007/s11356-018-3593-7DOI Listing
November 2018
3 Reads

Assessment of multiple anthropogenic contaminants and their potential genotoxicity in the aquatic environment of Plitvice Lakes National Park, Croatia.

Environ Monit Assess 2018 Oct 31;190(11):694. Epub 2018 Oct 31.

Mutagenesis Unit, Institute for Medical Research and Occupational Health, Ksaverska c. 2, PO Box 291, 10001, Zagreb, Croatia.

In this study, the influence of anthropogenic pollution on the aquatic environment of Plitvice Lakes National Park (PLNP) was investigated during 2011-2012 using a combination of chemical and cytogenetic analyses. Four groups of major contaminants [(volatile organic compounds: benzene, toluene, ethylbenzene, and xylenes (BTEX); persistent organochlorine pollutants: organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs); major and trace elements; anthropogenic radionuclides (Sr, Cs, and Cs)] were determined in three aquatic compartments (water, sediment, fish). Mass fractions of inorganic constituents in different compartments reflected the geological background of the area, indicating their origin from predominantly natural sources. Read More

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http://dx.doi.org/10.1007/s10661-018-7028-1DOI Listing
October 2018
2 Reads

Selective Photokilling of Human Pancreatic Cancer Cells Using Cetuximab-Targeted Mesoporous Silica Nanoparticles for Delivery of Zinc Phthalocyanine.

Molecules 2018 Oct 24;23(11). Epub 2018 Oct 24.

Institut Quimic de Sarria, Universitat Ramon Llull, Via Augusta 390, 08017 Barcelona, Spain.

Background: Photodynamic therapy (PDT) is a non-invasive and innovative cancer therapy based on the photodynamic effect. In this study, we sought to determine the singlet oxygen production, intracellular uptake, and in vitro photodynamic therapy potential of Cetixumab-targeted, zinc(II) 2,3,9,10,16,17,23,24-octa(tert-butylphenoxy))phthalocyaninato(2-)-N,N,N,N (ZnPcOBP)-loaded mesoporous silica nanoparticles against pancreatic cancer cells.

Results: The quantum yield () value of ZnPcOBP was found to be 0. Read More

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http://dx.doi.org/10.3390/molecules23112749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278564PMC
October 2018
15 Reads

Lethality of synthetic and natural acaricides to worker honey bees (Apis mellifera) and their impact on the expression of health and detoxification-related genes.

Environ Sci Pollut Res Int 2018 Dec 15;25(34):34730-34739. Epub 2018 Oct 15.

School of Environmental Sciences, Ontario Agricultural College, University of Guelph, 50 Stone Road East, Guelph, Ontario, N1G 2W1, Canada.

In this study, honey bees (Apis mellifera L.) were exposed to LD and LD doses of five commonly used acaricides for controlling the parasitic mite, Varroa destructor. LD values at 48 h post-treatment showed that tau-fluvalinate was the most toxic, followed by amitraz, coumaphos, thymol, and formic acid. Read More

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http://link.springer.com/10.1007/s11356-018-3205-6
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http://dx.doi.org/10.1007/s11356-018-3205-6DOI Listing
December 2018
5 Reads

The Correlation Between Length of Work and Nasal Mucociliary Transport Time of Gas/Fuel Station Workers.

Kobe J Med Sci 2018 May 28;64(1):E6-E10. Epub 2018 May 28.

Department of Ear Nose Throat-Head and Neck Surgery, Faculty of Medicine, Universitas Gadjah Mada/ Dr. Sardjito General Hospital, Yogyakarta, Indonesia.

Gasoline contains toxic substances such as benzene, toluene, ethylbenzene, xylene (BTEX) that negatively influence gas/fuel station workers' health via continuous inhalation, causing loss of cilia and epithelial cell necrosis of the nasal mucosa. The aim of this study is to determine the correlation between length of work with nasal mucociliary transport time (NMCTT) of the gas/fuel station workers This study used a cross sectional design. The data were obtained from anamnesis, physical and NMCTT examinations of gas station workers in Yogyakarta, during November 2013. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192822PMC
May 2018
2 Reads

Reuse of materials from a Sustainable Drainage System device: Health, Safety and Environment assessment for an end-of-life Pervious Pavement Structure.

Sci Total Environ 2019 Feb 26;650(Pt 2):1759-1770. Epub 2018 Sep 26.

GITECO-UC, Univ. of Cantabria, Avda de los Castros s/n. 39005, Santander, Spain.

Pervious pavement systems can have a life span of about 20years but, at end-of-life, it becomes necessary to evaluate the state of the infrastructure to determine whether they pose a health and safety risk to workers during dismantling, and also determine potential reuse of the waste material generated. In this paper, we report of an investigation conducted to evaluate whether Pervious pavement systems are hazardous to human health at end-of-life and also to assess the mobility of the stormwater pollutants trapped in the system as a measure of their potential release to receiving systems such as water-bodies and groundwater systems. After decommissioning, the pervious pavement structure was sampled for analysis including Gas Chromatography, inductively coupled plasma spectroscopy and, leachate analysis. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.09.224DOI Listing
February 2019
1 Read

[Study on the health effects of occupational exposure to low concentrations of benzene].

Authors:
Y M Cao W M Gao J Liu

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2018 Jun;36(6):435-438

No. 5 Suzhou People's Hospital, Suzhou 215137, China.

The main purpose of this study was to ascertain whether (or not) exposure to benzene, toluene, xylene and ethylbenzene (BTXE) , under normal working conditions, was associated with any health effects. From January to December 2014, the workplaces concentrations of BTXE were measured of 71 enterprises in Suzhou Industrial Park. Occupational health examination were investigated on 764 employees who exposed to BTXE, as well as 4409 employees of the corresponding enterprises who unexposed to BTXE, and analyzed the data of the two groups. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1001-9391.2018.06.010DOI Listing
June 2018
12 Reads

Medico-legal implications of toluene abuse and toxicity. Review of cases along with blood concentrations.

Leg Med (Tokyo) 2018 Sep 23;34:48-57. Epub 2018 Aug 23.

Department of Medical and Surgical Sciences, Unit of Legal Medicine, University of Bologna, Via Irnerio 49, 40126 Bologna, Italy. Electronic address:

Toluene, a liquid aromatic hydrocarbon, is one of the most widely used industrial solvents, and is present in numerous paints, paint thinners, glues and other industrial and household products. It has become the most abused solvent in the world due to its rapid effects following inhalation. However, the numerous cases of fatal and non-fatal toluene-related intoxication reported in the literature have not yet been collected and discussed in the forensic setting. Read More

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http://dx.doi.org/10.1016/j.legalmed.2018.08.008DOI Listing
September 2018
2 Reads

Herbicide Toxicity to Soybean-Rhizobium Symbiosis as Affected by Soil pH.

Bull Environ Contam Toxicol 2018 Oct 17;101(4):434-438. Epub 2018 Aug 17.

Department of Agronomy and Plant Breeding, Faculty of Agriculture, Bu-Ali Sina University, Hamadan, Islamic Republic of Iran.

The current study examined whether soil pH could influence the toxicity of herbicides to soybean-rhizobium symbiosis. This can be useful for farmers to minimize the toxicity of them to crop-rhizobium symbiosis via applying their reduced doses. The toxicity of bentazon, metribuzin, and trifluralin to soybean-rhizobium symbiosis was investigated in pH 6. Read More

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http://dx.doi.org/10.1007/s00128-018-2417-2DOI Listing
October 2018
5 Reads

Silica-Nanochannel-Based Interferometric Sensor for Selective Detection of Polar and Aromatic Volatile Organic Compounds.

Anal Chem 2018 Sep 24;90(18):10780-10785. Epub 2018 Aug 24.

Institute of Analytical Chemistry, Department of Chemistry , Zhejiang University , Hangzhou 310058 , China.

Public awareness of the toxicity of volatile organic compounds (VOCs) has led to increased requirements for direct measurement of these substances. This work reports the sensitive detection of VOCs at the ppb level by an interferometric sensor based on the multilayer silica-nanochannel membrane (MSNM). The MSNM is fabricated by layer-by-layer stacking of a free-standing ultrathin SNM composed of regularly ordered channels with an ultrasmall diameter of about 2. Read More

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http://dx.doi.org/10.1021/acs.analchem.8b01681DOI Listing
September 2018
11 Reads

Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line.

Parasit Vectors 2018 Jul 31;11(1):437. Epub 2018 Jul 31.

Department of Veterinary Sciences, University of Parma, 43126, Parma, Italy.

Background: Over-expression of ATP-binding cassette (ABC) transporter proteins has been implicated in resistance of ticks to acaricides. Tick cell lines are useful for investigating resistance mechanisms, as development of an in vitro model for the study of acaricide resistance would contribute to improving knowledge of the molecular basis behind drug processing and exclusion in ticks. In the present study, cultures of the Ixodes ricinus-derived cell line IRE/CTVM19 were treated with the acaricides amitraz, permethrin or fipronil to determine modulation of ABC transporter gene expression. Read More

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http://dx.doi.org/10.1186/s13071-018-3020-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069974PMC
July 2018
1 Read

Development and Validation of an Analytical Method to Quantitate Tris(chloroisopropyl)phosphate in Rat and Mouse Plasma using Gas Chromatography with Flame Photometric Detection.

J Anal Toxicol 2019 Jan;43(1):36-44

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, 111 Alexander Dr., Research Triangle Park, NC, USA.

Tris(chloropropyl)phosphate (TCPP) is an organophosphorus flame retardant (OPFR) and plasticizer increasingly used in consumer products and as a replacement for brominated flame retardants. Commercially available TCPP is a mixture of four structural isomers the most abundant of which is tris(1-chloro-2-propyl)phosphate (TCPP-1). Although there is a widespread use of TCPP and potential for human exposure, there is limited data on the safety or toxicity of TCPP. Read More

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http://dx.doi.org/10.1093/jat/bky048DOI Listing
January 2019

Synthesis of N-aryl substituted p-toluenesulphonamides via nickel catalyzed amidation reaction and their antibacterial, antifungal and antioxidant activities evaluation.

Pak J Pharm Sci 2018 Jul;31(4):1209-1216

Synthetic Medicinal Chemistry Unit, Department of Pure and Industrial Chemistry, University of Nigeria, Nsukka.

In present study nickel catalyzed synthesis of N-(aryl) substituted p-toluene sulphonamides is reported. The intermediate 4-methylbenzenesulphonamide (2) was obtained by the reaction between p-toluene sulphonyl chloride and ammonium hydroxide. Various readily available aryl halides (3a-e) Substituted p-toluene sulphonamides (4a-e) were obtained by coupling 4-methylbenezenesulphonamide (2) with via Buchwald-Hartwig cross-coupling reaction. Read More

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July 2018
20 Reads

Enhancement effect of earthworm (Eisenia fetida) on acetochlor biodegradation in soil and possible mechanisms.

Environ Pollut 2018 Nov 12;242(Pt A):728-737. Epub 2018 Jul 12.

Agro-Environmental Protection Institute, Ministry of Agriculture, MOA Key Laboratory of Original Agro-Environmental Pollution Prevention and Control, Tianjin 300191, China; College of Natural Resources and Environment, South China Agricultural University, Guangzhou 510642, China. Electronic address:

Acetochlor is a widely used chloroacetanilide herbicide and has posed environmental risks in soil and water due to its toxicity and high leaching capacity. Earthworm represents the dominant invertebrate in soil and can promote the decomposition of organic pollutants. The effect of earthworm on acetochlor degradation in soil was studied by soil column experiment with or without acetochlor and earthworm in sterile and natural soils. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02697491183034
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http://dx.doi.org/10.1016/j.envpol.2018.07.029DOI Listing
November 2018
28 Reads

Novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties.

J Biochem Mol Toxicol 2018 Sep 10;32(9):e22191. Epub 2018 Jul 10.

Department of Chemistry, Faculty of Sciences, Ataturk University, 25240, Erzurum, Turkey.

The thiolation reaction was carried out in a benzene solution at 80°C and p-substituted ketones and mercaptoacetic acid in a molar ratio (1:4) of in the presence of a catalytic amount of toluene sulfonic acids. The enzyme inhibition activities of the novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes derivatives were investigated. These novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes derivatives showed good inhibitory action against acetylcholinesterase (AChE) butyrylcholinesterase (BChE), and human carbonic anhydrase I and II isoforms (hCA I and II). Read More

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http://dx.doi.org/10.1002/jbt.22191DOI Listing
September 2018
2 Reads
1.925 Impact Factor

Effect of ozone injection on the long-term performance and microbial community structure of a VOCs biofilter.

J Environ Sci (China) 2018 Jul 23;69:133-140. Epub 2017 Sep 23.

Environmental Simulation and Pollution Control State Key Joint Laboratory, School of Environment, Tsinghua University, Beijing 100084, China; Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. Electronic address:

For biofilters treating waste gases containing volatile organic compounds (VOCs), biomass accumulation is a common problem which will induce bed clogging and significant decrease in VOCs removal efficiency during long-term operation. In this study, ozone injection was developed as a biomass control strategy, and its effects on the biofilter performance and the microbial community structure were investigated in long-term operation. Two biofilters, identified as BF1 and BF2, were operated continuously for 160 days treating gaseous toluene under the same conditions, except that 200 mg/m ozone was continuously injected into BF1 during days 45-160. Read More

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http://dx.doi.org/10.1016/j.jes.2017.09.008DOI Listing
July 2018
3 Reads

Toluene diisocyanate exposure and autotaxin-lysophosphatidic acid signalling.

Toxicol Appl Pharmacol 2018 09 22;355:43-51. Epub 2018 Jun 22.

Division of Occupational and Environmental Medicine, Lund University, SE 221 85 Lund, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE171 77 Stockholm, Sweden. Electronic address:

Toluene diisocyanate (TDI) is a reactive chemical used in manufacturing plastics. TDI exposure adversely affects workers' health, causing occupational asthma, but individuals differ in susceptibility. We recently suggested a role for signalling mediated by the enzyme autotaxin (ATX) and its product, lysophosphatidic acid (LPA), in TDI toxicity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0041008X183028
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http://dx.doi.org/10.1016/j.taap.2018.06.019DOI Listing
September 2018
20 Reads

Biodegradation of gaseous emissions of 2-chlorotoluene by strains of Rhodococcus sp. in polyurethane foam packed biotrickling filters.

Sci Total Environ 2018 Oct 28;639:1491-1500. Epub 2018 May 28.

Institute of Sanitary Engineering, Water Quality and Solid Waste Management, University of Stuttgart, Bandtäle 2, Stuttgart 70569, Germany.

About 60,000-70,000 tons of 2-chlorotoluene, which shows high toxicity in aquatic ecosystems, are produced worldwide and used in a tremendous field of applications. However, clear proofs of biodegradation were only presented for Comamonas testosteroni KT5 and Rhodococcus sp. OCT10. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.05.278DOI Listing
October 2018
2 Reads

Participation of voltage-gated sodium and calcium channels in the acute cardiac effects of toluene.

Toxicol Mech Methods 2018 Nov 31;28(9):670-677. Epub 2018 Jul 31.

c Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez" , Universidad Michoacana de San Nicolás de Hidalgo, Dr. Rafael Carrillo esquina Dr. Salvador González Herrejón, Col. Bosque Cuauhtémoc , Morelia , Mexico.

Inhaling solvents can lead to occurrence of cardiac arrhythmias and sudden sniffing death. Mechanisms related to this phenomenon are not fully understood. The purpose of this study was to investigate the effect of acute toluene exposure on heart reactivity to epinephrine and the participation of voltage-gated sodium and calcium channels. Read More

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http://dx.doi.org/10.1080/15376516.2018.1491664DOI Listing
November 2018
12 Reads

Synthesis, crystal structure, and cytotoxicity studies of titanacalix[4 and 8]arene complexes.

Dalton Trans 2018 Jul;47(27):8992-8999

Chemistry, School of Mathematics and Physical Sciences, University of Hull, Hull, HU6 7RX, UK.

Reaction of 5,11,17,23-tetra-tert-butyl-dihydroxy-26,28-bis(2-pentoxy)calix[4]arene (L(OH)2(Opentyl)2) with [TiCl4] afforded the dichlorotitanoacalix[4]arene complex [TiCl2L(O)2(Opentyl)2] (1) in good yield. Hydrolysis of 1 led to the isolation of the complex {[TiL(O)3(Opentyl)]2(μ-OH)(μ-Cl)} (2). Reaction of 5,11,17,23,29,35,41,47-p-tert-butyl-49,50,51,52,53,54,55,56-octapropoxycalix[8]arene (L'(Opropyl)8) with [TiCl4] in refluxing toluene afforded, following work-up, a 35 : 65 mixture (3) of the complex [Ti(NCMe)Cl]2[TiCl(μ-O)]2L' and the silicone grease derived complex [Ti(NCMe)Cl]2[Ti(μ-O)]2[OSi(CH3)2OSi(CH3)2O]L' in which the grease replaces two chloride ligands. Read More

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http://dx.doi.org/10.1039/c8dt01992dDOI Listing
July 2018
2 Reads

Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory.

Environ Health Prev Med 2018 Jun 19;23(1):24. Epub 2018 Jun 19.

Department of Environment Health, University of Occupational and Environmental Health, Kitakyushu, Japan.

Background: Plastic resins are complex chemicals that contain toluene diisocyanate (TDI) and/or trimellitic anhydride (TMA), which cause occupational allergies (OA), including respiratory allergies. Serum IgGs against TDI and TMA have been suggested as potential markers of the exposure status and as exploring cause of OA. Although TDI-specific IgG has been examined for suspected OA, TMA-specific IgG is not commonly evaluated in a urethane foam factory. Read More

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http://dx.doi.org/10.1186/s12199-018-0713-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010152PMC
June 2018
2 Reads

Draft genome sequence of Rhodococcus erythropolis B7g, a biosurfactant producing actinobacterium.

J Biotechnol 2018 Aug 4;280:38-41. Epub 2018 Jun 4.

Institute of Biosciences, Chemistry and Physics Faculty, TU Bergakademie Freiberg, 09599, Freiberg, Germany; Microbial Biotechnology, Ruhr University Bochum, 44780, Bochum, Germany. Electronic address:

Biosurfactants are amphipathic molecules with relevance in biotechnology due to their structural diversity, low toxicity and biodegradability. The genus Rhodococcus has extensively been studied because of its capacity to produce trehalose-containing surfactants as well as trehalose lipids as potential pathogenic factor. Here we present the draft genome sequence of Rhodococcus erythropolis B7g isolated with toluene from fuel-contaminated soil. Read More

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http://dx.doi.org/10.1016/j.jbiotec.2018.06.001DOI Listing
August 2018
2 Reads

Parental occupational exposure to solvents and heavy metals and risk of developing testicular germ cell tumors in sons (NORD-TEST Denmark).

Scand J Work Environ Health 2018 11 7;44(6):658-669. Epub 2018 Jun 7.

Section of Environment and Radiation, International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon CEDEX 08, France.

Objective The present study aims to assess if parental occupational exposure to solvents or heavy metals is associated with risk of testicular germ cell tumors (TGCT) in sons in Denmark. Methods The NORD-TEST Denmark included 3421 cases diagnosed with TGCT at ages 14-49 years in Denmark between 1981 and 2014. Controls (N=14 024) selected from the central population registry were matched to cases on birth year. Read More

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http://www.sjweh.fi/show_abstract.php?abstract_id=3732
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http://dx.doi.org/10.5271/sjweh.3732DOI Listing
November 2018
7 Reads

Green synthesis and characterizations of gold nanoparticles using Thyme and survey cytotoxic effect, antibacterial and antioxidant potential.

J Photochem Photobiol B 2018 Jul 19;184:71-79. Epub 2018 May 19.

Department of Chemistry, Payame Noor University, Tehran, Iran. Electronic address:

Nowadays, green chemistry methods are noticeable for synthesis metal nanoparticles due to affordable, easy and high reaction rate. In the present study gold nanoparticles (Au NPs) were eco-friendly synthesized using Thyme extract at the room temperature for 30 min to provide non-toxic, which can be used for different applications. Identifying properties of synthesized gold nanoparticles was done by various analytical technique including UV-Vis absorption spectroscopy approved presence of Au NPs in the solution, the functional groups of Thyme extract in the reduction and capping process of Au NPs are determined by FT-IR, Crystalline with the fcc plane approved by X-ray diffraction (XRD) pattern, energy dispersive spectroscopy (EDS) determined existence of elements in the sample, surface morphology, diverse shapes and size of present Au NPs were showed by scanning electron microscopy (SEM), atomic force microscopy (AFM) and Transmission electron microscopy (TEM). Read More

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http://dx.doi.org/10.1016/j.jphotobiol.2018.05.016DOI Listing
July 2018
3 Reads

[Indirect and mixed mechanisms of action in toxic myopathies].

Ann Pharm Fr 2018 Jul 24;76(4):273-285. Epub 2018 May 24.

Service de toxicologie, CHU Bab-El-Oued, rue Mohamed Lamine Debaghine, 16009 Alger, Algérie; Centre national de toxicologie, route du petit Staouali Delly Brahim, 16062 Alger, Algérie.

Toxic myopathies are a group of pathologies characterized by a structural and/or functional disturbance of muscles induced by an exogenous agent. The most frequent are those induced by drugs used in clinical practice. Illegal drugs, pesticides, solvents, metals and even physical and gaseous agents can cause this kind of disease and exert toxicity on muscle tissues. Read More

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http://dx.doi.org/10.1016/j.pharma.2018.03.004DOI Listing
July 2018
5 Reads

An epidemic of bladder cancer: ten cases of bladder cancer in male Japanese workers exposed to ortho-toluidine.

J Occup Health 2018 Jul 9;60(4):307-311. Epub 2018 May 9.

National Institute of Occupational Safety and Health.

Background: ortho-Toluidine (OT) was listed as a Group 1 carcinogen by the International Agency for Research on Cancer in 2012 based on epidemiological observations of workers co-exposed to OT and aromatic amines. From 2014 to 2017, several cases of bladder cancer (BCa) secondary to occupational exposure, primarily to OT, were detected in Japan.

Objective: To describe 10 cases of BCa in male Japanese workers exposed primarily to OT at two plants that produce organic dye and pigment intermediates. Read More

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http://dx.doi.org/10.1539/joh.2017-0220-OADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078838PMC
July 2018
1 Read

The sensitivity of a deep-sea fish species (Anoplopoma fimbria) to oil-associated aromatic compounds, dispersant, and Alaskan North Slope crude oil.

Environ Toxicol Chem 2018 08 21;37(8):2210-2221. Epub 2018 Jun 21.

Department of Biology and Marine Biology, University of North Carolina, Wilmington, North Carolina, USA.

A predominant concern following oil spills is toxicity to aquatic organisms. However, few data are available on effects in deep-sea cold water fishes. The present study had 3 major objectives. Read More

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http://doi.wiley.com/10.1002/etc.4165
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http://dx.doi.org/10.1002/etc.4165DOI Listing
August 2018
12 Reads

Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products.

Int J Environ Res Public Health 2018 04 13;15(4). Epub 2018 Apr 13.

School of Environmental Engineering, University of Seoul, Seoulsiripdaero 163, Dongdaemun-gu, Seoul 02504, Korea.

The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the concern over the potential health risks associated with the hazardous ingredients in deodorizing consumer products, 17 ingredients were analyzed and assessed according to their health risk on 3 groups by the application type in 47 deodorizing products. Read More

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http://dx.doi.org/10.3390/ijerph15040744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923786PMC
April 2018
8 Reads

Zafirlukast and vincamine ameliorate tamoxifen-induced oxidative stress and inflammation: Role of the JNK/ERK pathway.

Life Sci 2018 Jun 4;202:78-88. Epub 2018 Apr 4.

Pharmacology & Toxicology Department, Faculty of Pharmacy, Cairo University, Egypt. Electronic address:

Aims: This study investigated the hepatoprotective effects of both zafirlukast and vincamine and their possible role in the treatment of tamoxifen-induced liver injury in rats.

Materials And Methods: Female Wistar rats were divided into five groups (10 rats each). Groups I and II received 1% Tween 80 and served as normal and tamoxifen controls, respectively. Read More

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http://dx.doi.org/10.1016/j.lfs.2018.04.002DOI Listing
June 2018
12 Reads
2.700 Impact Factor

Combined effects of four pesticides and heavy metal chromium (Ⅵ) on the earthworm using avoidance behavior as an endpoint.

Ecotoxicol Environ Saf 2018 Aug 3;157:191-200. Epub 2018 Apr 3.

State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control / Lab (Hangzhou) for Risk Assessment of Agricultural Products of Ministry of Agriculture / Key Laboratory for Pesticide Residue Detection of Ministry of Agriculture/Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China. Electronic address:

In natural ecosystems, organisms are commonly exposed to chemical mixtures rather than individual compounds. However, environmental risk is traditionally assessed based on data of individual compounds. In the present study, we aimed to investigate the individual and combined effects of four pesticides [fenobucarb (FEN), chlorpyrifos (CPF), clothianidin (CLO), acetochlor (ACE)] and one heavy metal chromium [Cr(Ⅵ)] on the earthworm (Eisenia fetida) using avoidance behavior as an endpoint. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2018.03.067DOI Listing
August 2018
4 Reads
2.762 Impact Factor

Chemical tick control practices in southwestern and northwestern Uganda.

Ticks Tick Borne Dis 2018 05 15;9(4):945-955. Epub 2018 Mar 15.

National Research Center for Protozoan Diseases (NRCPD), Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro 080-8555, Hokkaido, Japan; Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan. Electronic address:

Tick acaricide failure is one of the leading challenges to cattle production in Uganda. To gain an understanding into the possible drivers of acaricide failure, this study characterized the current chemical tick control practices in the southwestern (Mbarara, Mitooma and Rukungiri districts) and northwestern (Adjumani district) regions of Uganda. A total of 85 farms participated in a survey that utilized a semi-structured questionnaire. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.03.009DOI Listing
May 2018
6 Reads

Estrogen therapy in patients with prostate cancer: a contemporary systematic review.

Int Urol Nephrol 2018 Jun 29;50(6):993-1003. Epub 2018 Mar 29.

UROGIV Research Group, School of Medicine, Universidad del Valle, Cali, Colombia.

Purpose: To evaluate the effectiveness and harms of DES in treating prostate cancer compared to other forms of androgen deprivation therapy (orchiectomy, LHRH agonists, and anti-androgens).

Methods: We included clinical trials comparing DES with other forms of ADT (bicalutamide, flutamide, LHRH agonists, or orchiectomy) in PCa treatment. The primary outcomes were overall survival, cancer-specific survival, and progression-free survival, and secondary outcomes were cardiovascular effects. Read More

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http://dx.doi.org/10.1007/s11255-018-1854-5DOI Listing
June 2018
4 Reads

Quantitative measurement of oxidative damage in erythrocytes as indicator in benzene intoxications.

Toxicol Mech Methods 2018 Jul 12;28(6):450-460. Epub 2018 Apr 12.

a Laboratorio de microRNAs de la Unidad Académica de Ciencias Biológicas de la Universidad Autónoma de Zacatecas , Zacatecas , Mexico.

The metabolism of aromatic hydrocarbons by the organism forms products that cause cell death depending on the type of exposure. Benzene exposure has been linked to oxidative stress, hepatic damage, aplastic anemia, and hematopoietic cancer as lymphoid and myeloid leukemia. However, there are not fast methods to evaluate chronic benzene exposure in human blood. Read More

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http://dx.doi.org/10.1080/15376516.2018.1455786DOI Listing
July 2018
15 Reads

Skin sensitization quantitative risk assessment for occupational exposure of hairdressers to hair dye ingredients.

Regul Toxicol Pharmacol 2018 Jun 9;95:124-132. Epub 2018 Mar 9.

Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.

Occupational exposure of hairdressers to hair dyes has been associated with the development of allergic contact dermatitis (ACD) involving the hands. p-Phenylenediamine (PPD) and toluene-2,5-diamine (PTD) have been implicated as important occupational contact allergens. To conduct a quantitative risk assessment for the induction of contact sensitization to hair dyes in hairdressers, available data from hand rinsing studies following typical occupational exposure conditions to PPD, PTD and resorcinol were assessed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02732300183007
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http://dx.doi.org/10.1016/j.yrtph.2018.03.006DOI Listing
June 2018
30 Reads

Characteristics and health effects of BTEX in a hot spot for urban pollution.

Ecotoxicol Environ Saf 2018 Jul 3;155:133-143. Epub 2018 Mar 3.

Research Center for Health Sciences, Department of Environmental Health Engineering, Shiraz University of Medical Sciences, Shiraz, Iran.

This study reports a spatiotemporal characterization of toluene, benzene, ethylbenzene, and xylenes concentrations (BTEX) in an urban hot spot in Iran, specifically at an bus terminal region in Shiraz. Sampling was carried out according to NIOSH Compendium Method 1501. The inverse distance weighting (IDW) method was applied for spatial mapping. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01476513183015
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http://dx.doi.org/10.1016/j.ecoenv.2018.02.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916771PMC
July 2018
30 Reads

Effects of volatile organic compounds and carbon monoxide mixtures on learning and memory, oxidative stress, and monoamine neurotransmitters in the brains of mice.

Toxicol Ind Health 2018 Mar 5;34(3):178-187. Epub 2018 Mar 5.

4 College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.

In this study, we investigated the effect of inhaled mixtures of volatile organic compounds (VOCs) and carbon monoxide (CO) on neuroethology. Fifty 6-week-old male Kunming mice were exposed in five similar static chambers; zero (control) and four different doses of VOC and CO mixtures (G1-G4) for 10 consecutive days and 2 h/day. The compounds and concentrations were as follows: formaldehyde, benzene, toluene, xylene, and CO as 0. Read More

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http://dx.doi.org/10.1177/0748233717747504DOI Listing
March 2018
26 Reads

Performance and bacterial diversity of biotrickling filters filled with conductive packing material for the treatment of toluene.

Bioresour Technol 2018 Jun 24;257:201-209. Epub 2018 Feb 24.

Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Department of Chemistry, Yanbian University, Yanji 133002, China; Analytical and Testing Center, Yanbian University, Yanji 133002, China. Electronic address:

Toluene has high toxicity and mutagenicity, thus, the removal of toluene from air is necessary. In this study, two biotrickling filters (BTFs) were constructed and packed with conductive packing material to treat toluene waste gas. BTF-O exhibited good toluene removal performance even under high toluene inlet concentration, and over 80% of removal efficiency was observed. Read More

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http://dx.doi.org/10.1016/j.biortech.2018.02.108DOI Listing
June 2018
30 Reads

Ecotoxicity tests with Allium cepa to determine the efficiency of rice husk ash in the treatment of groundwater contaminated with benzene, toluene, ethylbenzene, and xylene.

Environ Sci Pollut Res Int 2018 May 23;25(13):12849-12858. Epub 2018 Feb 23.

Mines, Metallurgical and Materials Engineering Graduate Program - UFRGS, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

The validation of adsorption treatment based on toxicity assays aims to assess the actual environmental impact caused by effluents after treatment. This study describes the use of rice husk ash as adsorbent and evaluates the efficiency of adsorption treatment to remediate groundwater contaminated with benzene, toluene, ethylbenzene, and xylene (BTEX). The synthetic effluent was prepared with standard benzene, toluene, ethylbenzene, and xylene solutions. Read More

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http://dx.doi.org/10.1007/s11356-018-1512-6DOI Listing
May 2018
4 Reads

Comparative inhalation toxicity of ethyltoluene isomers in rats and mice.

Inhal Toxicol 2017 Oct - Dec;29(12-14):577-585. Epub 2018 Jan 29.

a Division of the National Toxicology Program , RTP , NC , USA.

The C9 alkylbenzenes, composed mostly of ethyltoluenes and trimethylbenzenes, comprise 75-90% of the naphtha fraction of crude oil. Occupational and environmental exposure to C9 alkylbenzenes occur via inhalation. We conducted short-term inhalation studies on the ethyltoluene isomers (2-, 3- or 4-) to select one isomer for more comprehensive studies. Read More

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https://www.tandfonline.com/doi/full/10.1080/08958378.2018.1
Publisher Site
http://dx.doi.org/10.1080/08958378.2018.1430190DOI Listing
January 2019
8 Reads

In vitro genotoxicity assessment of dinitroaniline herbicides pendimethalin and trifluralin.

Food Chem Toxicol 2018 Mar 31;113:90-98. Epub 2018 Jan 31.

Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Turkey.

Pendimethalin and trifluralin are widely used dinitroaniline herbicides. Both compounds can be found as residue levels in agricultural products. This study was conducted in order to provide necessary information for the risk assessment of pendimethalin and trifluralin. Read More

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http://dx.doi.org/10.1016/j.fct.2018.01.034DOI Listing
March 2018
3 Reads

A novel mouse model of atopic dermatitis that is T helper 2 (Th2)-polarized by an epicutaneous allergen.

Environ Toxicol Pharmacol 2018 Mar 29;58:122-130. Epub 2017 Dec 29.

Department of Stem Cell and Regenerative Biology, Konkuk University, 120 Neungdongro, Gwangjin-gu, Seoul 05029, Republic of Korea. Electronic address:

The pathogenesis of atopic dermatitis (AD) involves T helper 2 (Th2) cells, and effective therapies remain elusive due to the paucity of animal models. We aimed to develop a mouse model of an immune system aberration caused by allergen. Experiments were conducted in two phases. Read More

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http://dx.doi.org/10.1016/j.etap.2017.12.025DOI Listing
March 2018
13 Reads