2,959 results match your criteria Toxicity Toluene


["Attenuation-preservation effects" of different processed products of Aconiti Kusnezoffii Radix in industrialized production].

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(8):1901-1908

Anhui Wansheng Chinese Herbal Pieces Co., Ltd. Fuyang 236112, China Anhui Provincial Processing Engineering Research Center of Traditional Chinese Medicine Decoction Pieces Fuyang 236112, China.

To study the correlation between toxicity and efficacy of different processed Aconiti Kusnezoffii Radix productsin industrial production, in order to define the optimal processing method for "attenuation-preservation effects". The HPLC method was used to determine the content of six aconitine alkaloids in Aconiti Kusnezoffii Radix and its different processed products. The Bliss method was used to determine the half-lethal dose(LD_(50)) or the maximum dose of Aconiti Kusnezoffii Radix and its different processed products in mice. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20200207.310DOI Listing

Antioxidant properties of eugenol, butylated hydroxylanisole, and butylated hydroxyl toluene with key biomolecules relevant to Alzheimer's diseases-In vitro.

J Food Biochem 2020 May 26:e13276. Epub 2020 May 26.

Functional Foods, Nutraceuticals and Phytomedicine Laboratory, Department of Biochemistry, Federal University of Technology Akure, Akure, Nigeria.

This research work examined and likened effect of eugenol a natural phenolic compound with butylated hydroxylanisole (BHA) and butylated hydroxyl toluene (BHT) synthetic phenolic compounds with key biomolecules [acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and monoamine oxidase (MAO)] relevant to Alzheimer's diseases (AD) in vitro. Ten millimolar each sample was prepared in a mixture of ethanol and water (1:1 v/v), and the interactions with AChE, BChE, and MAO were evaluated. Still, ferric reducing antioxidant property, ABTS radicals scavenging ability and lipid peroxidation were carried out. Read More

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http://dx.doi.org/10.1111/jfbc.13276DOI Listing

Impact of industrial activities on atmospheric volatile organic compounds in Sihwa-Banwol, the largest industrial area in South Korea.

Environ Sci Pollut Res Int 2020 May 17. Epub 2020 May 17.

Department of Environmental Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea.

The impact of industrial activities on atmospheric volatile organic compounds (VOCs) in the Sihwa-Banwol complexes, i.e., the largest industrial area in Korea, was investigated. Read More

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http://dx.doi.org/10.1007/s11356-020-09217-xDOI Listing

Indoor generated PM compositions and volatile organic compounds: Potential sources and health risk implications.

Chemosphere 2020 May 5;255:126932. Epub 2020 May 5.

Department of Earth Sciences and Environment, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, 43600, Selangor, Malaysia.

The aim of the present study was to investigate the potential sources of heavy metals in fine air particles (PM) and benzene, toluene, ethylbenzene, and isomeric xylenes (BTEX) in gas phase indoor air. PM samples were collected using a low volume sampler. BTEX samples were collected using passive sampling onto sorbent tubes and analyzed using gas chromatography-mass spectrometry (GC-MS). Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.126932DOI Listing

A novel UV-assisted PEC-MFC system with CeO/TiO/ACF catalytic cathode for gas phase VOCs treatment.

Chemosphere 2020 May 3;255:126930. Epub 2020 May 3.

Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China.

Emissions of volatile organic compounds (VOCs) air pollutants could worsen air quality and adversely affect human health, thus developing more efficient low-temperature VOCs removal techniques is desired. A novel continuous system integrating UV-assisted photo-electrochemical catalysis with microbial fuel cell (UV-assisted PEC-MFC) has been established for promoting removal of gaseous ethyl acetate or toluene and generating electricity simultaneously. In this system, CeO/TiO/ACF catalytic cathode is prepared and used for combination with bio-anode for accelerating cathodic reaction. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.126930DOI Listing

Critical evaluation of human health risks due to hydraulic fracturing in natural gas and petroleum production.

Arch Toxicol 2020 Apr 9;94(4):967-1016. Epub 2020 May 9.

Leibniz Research Centre for Working Environment and Human Factors (IfADo), University of Dortmund, Dortmund, Germany.

The use of hydraulic fracturing (HF) to extract oil and natural gas has increased, along with intensive discussions on the associated risks to human health. Three technical processes should be differentiated when evaluating human health risks, namely (1) drilling of the borehole, (2) hydraulic stimulation, and (3) gas or oil production. During the drilling phase, emissions such as NO, NMVOCs (non-methane volatile organic compounds) as precursors for tropospheric ozone formation, and SO have been shown to be higher compared to the subsequent phases. Read More

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http://dx.doi.org/10.1007/s00204-020-02758-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225182PMC

Ecological risk assessment (ERA) based on contaminated groundwater to predict potential impacts to a wetland ecosystem.

Environ Sci Pollut Res Int 2020 May 3. Epub 2020 May 3.

Department of Sanitary and Environmental Engineering, Rio de Janeiro State University (UERJ), 524 São Francisco Xavier Street, Rio de Janeiro, 20550-900, Brazil.

To assess the ecological risk resulting from an accidental gasoline spill upstream from a wetland, groundwater and sediment sampling was carried out during two campaigns at the 48th and 52nd months after the spill had occurred. In total, 21 groundwater monitoring wells in the affected area were sampled plus an additional reference well located upstream from the accident location. Seven sediment sampling points were selected inside the wetland, plus a reference point upstream from the accident. Read More

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http://dx.doi.org/10.1007/s11356-020-08755-8DOI Listing

Safety assessment of a new benzoylphenylurea TXH09 and its efficacy against two borers Ostrinia furnacalis and Grapholitha molesta in field.

Ecotoxicol Environ Saf 2020 Jul 10;197:110591. Epub 2020 Apr 10.

Shanghai Key Laboratory of Biological Chemistry, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China. Electronic address:

Benzoylphenylureas as an important type of insect growth regulators, acting on the moulting stage in immature insects, are highly effective and low toxic. The new benzoylphenylurea TXH09 [N-((2,6-dimethyl-4-(heptafluoropropyl-2-yl)phenyl)carbamoyl)-2,6-difluorobenzamide] has high efficacy against chewing insect pests harming vegetables and rice. In this paper, the efficacy of TXH09 against two intractable borers Ostrinia furnacalis and Grapholitha molesta were evaluated in field, and safety assessment by exploring the characteristics of photodegradation, cytotoxicity, micronucleus generation and chromosome aberration was performed. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2020.110591DOI Listing

Role of functional groups in reaction kinetics of dithiothreitol with secondary organic aerosols.

Environ Pollut 2020 Mar 29;263(Pt B):114402. Epub 2020 Mar 29.

Department of Environmental Sciences, University of California, Riverside, CA, 92521, United States; Environmental Toxicology Graduate Program, University of California, Riverside, CA, 92521, United States. Electronic address:

The toxicity of organic aerosols has been largely ascribed to the generation of reactive oxygen species, which could subsequently induce oxidative stress in biological systems. The reaction of DTT with redox-active species in PM has been generally assumed to be pseudo-first order, with the oxidative potential of PM being represented by the DTT consumption per minute of reaction time per μg of PM. Although catalytic reactive species such as transition metals and quinones are long believed to be the main contributors of DTT responses, the role of non-catalytic DTT reactive species such as organic hydroperoxides (ROOH) and electron-deficient alkenes (e. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114402DOI Listing

Biological significance of aminophenyl-β-carboline derivatives formed from co-mutagenic action of β-carbolines and aniline and o-toluidine and its effect on tumorigenesis in humans: A review.

Mutat Res 2020 Feb - Mar;850-851:503148. Epub 2020 Jan 28.

Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan.

Norharman exists in cigarette smoke and cooked foods and is non-mutagenic among Salmonella strains but mutagenic to S. typhimurium TA98 and YG1024 in the presence of S9 mix and aniline and o-toluidine. Co-mutagenesis of β-carbolines and aniline and o-toluidine occurs through the formation of novel mutagenic aminophenyl-β-carboline derivatives including 9-(4'-aminophenyl)-9H-pyrido[3,4-b]indole [aminophenylnorharman] (APNH)] and 9-(4'- amino-3'-methylphenyl)-9H-pyrido[3,4-b]indole [aminomethylphenylnorharman] (AMPNH)]. Read More

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http://dx.doi.org/10.1016/j.mrgentox.2020.503148DOI Listing

An optical detection module-based biosensor using fortified bacterial beads for soil toxicity assessment.

Anal Bioanal Chem 2020 May 18;412(14):3373-3381. Epub 2020 Feb 18.

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul, 02841, Republic of Korea.

An optical biosensor module for soil contamination assessment is presented, employing bioluminescent bacterial bioreporters encapsulated in poly-dopamine (PD)-coated alginate microbeads. The PD-coated beads displayed improved mechanical strength and stability, but somewhat delayed responses to the inducing toxicant. Using toluene as a model soil contaminant, two bioluminescent reporter strains were employed for its detection in the ambient light-blocking, temperature-controlled biosensor module. Read More

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http://dx.doi.org/10.1007/s00216-020-02469-zDOI Listing

Bioaccumulation of BTEX and PAHs in (Actinopterygii) from the Epe Lagoon, Lagos, Nigeria.

Heliyon 2020 Jan 30;6(1):e03272. Epub 2020 Jan 30.

Department of Zoology, University of Lagos, Lagos State, Nigeria.

Toxicity studies in the aquatic ecosystem have shown that petrol and its product have adverse effects on aquatic biota. They are able to easily absorb these toxic substances into their bodies from sediment, water or even food items that are contaminated, thus impacting the food chain. In this study, water, sediment and fish () from the Epe Lagoon were investigated for the presence of BTEX (benzene, toluene, ethylbenzene and the three xylene isomers m, o and p-xylenes), and PAHs using GC-MS. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000791PMC
January 2020

Novel heterocyclic chitosan derivatives and their derived nanoparticles: Catalytic and antibacterial properties.

Int J Biol Macromol 2020 Apr 25;149:682-692. Epub 2020 Jan 25.

Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St. 6, Moscow, 117198, Russian Federation; Zelinsky Institute of Organic Chemistry RAS, Leninsky Prosp. 47, Moscow 119991, Russian Federation.

The metal-assisted nitrone-nitrile cycloaddition reaction is apply to empower chitosan chemistry. The ultrasonic irradiation has proven to efficiently accelerate the cycloaddition affording new heterocyclic (1,2,4-oxadiazoline) chitosan derivatives and avoiding ultrasonic degradation of the chitosan macromolecules. By varying the nitrone nature, both water- and toluene-soluble chitosan derivatives were successfully synthesized. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.12.277DOI Listing

Do trifluralin and tebuthiuron impair isolated rat liver mitochondria?

Pestic Biochem Physiol 2020 Feb 18;163:175-184. Epub 2019 Nov 18.

Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Departamento de Química, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil; Instituto Nacional de Tecnologias Alternativas de Detecção, Avaliação Toxicológica e Remoção de Micropututantes e Radioativos (INCT-DATREM), Unesp, Instituto de Química, Caixa Postal 355, CEP: 14800-900, Araraquara, SP, Brazil.

Emerging contaminants, such as the herbicides trifluralin and tebuthiuron, comprise a class of compounds for which toxicological data are lacking, especially data regarding their harmful effects and biomarkers of exposure. Their potential damage to the environment and non-target organisms makes understanding their toxic mechanisms an urgent matter. Mitochondria, which exert an energy production function, play a vital role in maintaining many cellular activities and therefore are reliable predictors of substance toxicity. Read More

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http://dx.doi.org/10.1016/j.pestbp.2019.11.012DOI Listing
February 2020

Efficient Two-Dimensional Tin Halide Perovskite Light-Emitting Diodes via a Spacer Cation Substitution Strategy.

J Phys Chem Lett 2020 Feb 28;11(3):1120-1127. Epub 2020 Jan 28.

Beijing Advanced Innovation Center for Soft Matter Science and Engineering , Beijing University of Chemical Technology , Beijing 100029 , China.

Lead halide perovskites have attracted tremendous attention because of their impressive optoelectronic properties. However, the toxicity of lead remains a bottleneck for further commercial development. Two-dimensional Ruddlesden-Popper tin-based perovskites are lead-free and more stable compared to their three-dimensional counterparts, which have great potential in the optoelectronic device field. Read More

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http://dx.doi.org/10.1021/acs.jpclett.9b03565DOI Listing
February 2020

Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants.

BMC Pharmacol Toxicol 2019 12 19;20(Suppl 1):75. Epub 2019 Dec 19.

Laboratory of Toxicology (LATOX), Department of Analysis, Pharmacy Faculty, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.

Background: Gasoline is a complex mixture of saturated and unsaturated hydrocarbons, in which aromatic compounds, such as BTX (benzene, toluene, and xylene) feature as the main constituents. Simultaneous exposure to these aromatic hydrocarbons causes a significant impact on benzene toxicity. In order to detect early alterations caused in gasoline station attendants exposed to BTX compounds, immunological, inflammatory, and oxidative stress biomarkers were evaluated. Read More

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http://dx.doi.org/10.1186/s40360-019-0355-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921377PMC
December 2019

Exploring Mechanistic Toxicity of Mixtures Using PBPK Modeling and Computational Systems Biology.

Toxicol Sci 2020 Mar;174(1):38-50

Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia.

Mixtures risk assessment needs an efficient integration of in vivo, in vitro, and in silico data with epidemiology and human studies data. This involves several approaches, some in current use and others under development. This work extends the Agency for Toxic Substances and Disease Registry physiologically based pharmacokinetic (PBPK) toolkit, available for risk assessors, to include a mixture PBPK model of benzene, toluene, ethylbenzene, and xylenes. Read More

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http://dx.doi.org/10.1093/toxsci/kfz243DOI Listing

Mechanisms of the direct effects of oil-related contaminants on ovarian cells.

Environ Sci Pollut Res Int 2020 Feb 17;27(5):5314-5322. Epub 2019 Dec 17.

Zoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.

We studied the influence of oil-related environmental contaminants (OREC) on the viability, hormone secretion, and protein expression using cultured porcine ovarian granulosa cells. Addition of benzene and xylene promoted proliferation and apoptosis and reduced ovarian cell viability whereas toluene induced apoptosis only. The release of progesterone (P4) and oxytocin (OT) was promoted by benzene and xylene, and suppressed by toluene while prostaglandin F (PGF) output was stimulated by benzene and toluene, but not xylene. Read More

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http://dx.doi.org/10.1007/s11356-019-07295-0DOI Listing
February 2020

Synergistic effect of heartwood extracts in combination with linseed oil as wood preservatives against subterranean termite Heterotermes indicola (Blattodea: Rhinotermitidae).

Environ Sci Pollut Res Int 2020 Jan 14;27(3):3076-3085. Epub 2019 Dec 14.

Nuclear Institute for Food and Agriculture (NIFA) Peshawar, Peshawar, Khyber-Pakhtunkhwa Province, Pakistan.

This study evaluated the effect of wood extracts from Tectona grandis, Dalbergia sissoo, Cedrus deodara, and Pinus roxburghii combined with linseed oil as protectants of two non-durable wood species against the termite, Heterotermes indicola. Heartwood blocks (19 × 19 × 19 mm) and wood shavings were extracted using an ethanol/toluene (2:1) solvent system. Results of choice and no-choice tests with solvent-extracted and non-extracted heartwood blocks showed greater wood mass loss from termite feeding on solvent-extracted blocks compared with non-extracted blocks for all wood species. Read More

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http://dx.doi.org/10.1007/s11356-019-07202-7DOI Listing
January 2020
2.828 Impact Factor

Frequently encountered pesticides can cause multiple disorders in developing worker honey bees.

Environ Pollut 2020 Jan 11;256:113420. Epub 2019 Nov 11.

Entomology and Nematology Department, University of Florida, Steinmetz Hall, 970 Natural Area Drive, Gainesville, FL, 32611, USA.

Pesticide exposure is regarded as a contributing factor to the high gross loss rates of managed colonies of Apis mellifera. Pesticides enter the hive through contaminated nectar and pollen carried by returning forager honey bees or placed in the hive by beekeepers when managing hive pests. We used an in vitro rearing method to characterize the effects of seven pesticides on developing brood subjected dietary exposure at worse-case environmental concentrations detected in wax and pollen. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.113420DOI Listing
January 2020

Remediation of BTEX and Cr(VI) contamination in soil using bioelectrochemical system-an eco-friendly approach.

Environ Sci Pollut Res Int 2020 Jan 7;27(1):837-845. Epub 2019 Dec 7.

Division of Biotechnology, Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan, Jeonbuk, 54596, South Korea.

Soil contamination with benzene, toluene, ethylbenzene and xylene isomers (BTEX) has raised increasing concern because of its high solubility in water and toxicity to biotic communities. This study aims at investigating the process and prospects of deploying bioelectrochemical system (BES) for the removal of BTEX from artificially contaminated soil using Pseudomonas putida YNS1, alongside the reduction of hexavalent chromium (Cr(VI)). The BES was setup with desired operating conditions: initial concentration of BTEX (50-400 mg/L in 100 mL of sterilized water), pH (4-10) and applied potential voltage (0. Read More

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http://dx.doi.org/10.1007/s11356-019-07029-2DOI Listing
January 2020

Environmental and Health Effects of Benzene Exposure among Egyptian Taxi Drivers.

J Environ Public Health 2019 3;2019:7078024. Epub 2019 Feb 3.

Industrial Health and Occupational Medicine, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.

Objectives: To study environmental exposure to benzene as well as hematological effects of benzene exposure in taxi drivers.

Background: Exposure to benzene has been associated with adverse health effects, including haematopoietic disorders.

Methods: A retrospective cohort study was carried out from the beginning of April 2017, through the end of June 2018, on 280 taxi drivers (the exposed group) and 120 unexposed matched individuals (controls). Read More

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http://dx.doi.org/10.1155/2019/7078024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855039PMC

Upward translocation of acetochlor and atrazine in wheat plants depends on their distribution in roots.

Sci Total Environ 2020 Feb 20;703:135636. Epub 2019 Nov 20.

Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310029, China; The Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang University, Hangzhou 310029, China; The Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China. Electronic address:

Residual acetochlor and atrazine in soils, resulting from their extensive application to maize plants, may affect product safety of the ultimate wheat crop. To determine the potential uptake and accumulation of acetochlor and atrazine by wheat plants, the uptake mechanism, translocation, and subcellular distribution of these two herbicides were studied through hydroponic experiments (10 mg L). The results indicated that acetochlor can be taken up through the apoplastic pathway and can accumulate in wheat roots with little upward translocation. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.135636DOI Listing
February 2020

Toxicity assessment of the herbicide acetochlor in the human liver carcinoma (HepG2) cell line.

Chemosphere 2020 Mar 9;243:125345. Epub 2019 Nov 9.

Center for Environmental and Human Toxicology, Department of Physiological Sciences, College of Veterinary Medicine, UF Genetics Institute, Interdisciplinary Program in Biomedical Sciences Neuroscience, University of Florida, Gainesville, FL, 32611, USA. Electronic address:

Acetochlor is a high-volume herbicide used on a global scale and toxicity assessments are needed to define its potential for adverse effects in wildlife and humans. This study was conducted to determine the effects of acetochlor on human liver carcinoma cells (HepG2), a cell model widely used to assess the potential for chemical hepatotoxicity. Experiments were conducted at concentrations ranging 0-800 μM acetochlor over a 12 to 48h period to quantify underlying mechanisms of toxicity. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.125345DOI Listing

A comprehensive comparison and analysis of soil screening values derived and used in China and the UK.

Environ Pollut 2020 Jan 19;256:113404. Epub 2019 Oct 19.

Lancaster Environment Centre (LEC), Lancaster University, Lancaster, LA1 4YQ, UK. Electronic address:

China and the UK use different risk-based approaches to derive soil screening or guideline values (SSVs; SGVs) for contaminants. Here we compare the approaches and the derived values for 6 illustrative contaminants. China's SSVs are derived using an approach developed in the US as follows: for carcinogens, acceptable level of risk (ACR) is set at 10 and the SSVs calculated as 10 divided by the soil exposure and toxicity data; for non-carcinogens, the hazard quotient is 1 and the SSV is calculated as 1 divided by the soil exposure and toxicity data. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.113404DOI Listing
January 2020

1,2-Benzenedithiol and Toluene-3,4-dithiol Arsenic(III) Complexes-Synthesis, Structure, Spectroscopic Characterization and Toxicological Studies.

Molecules 2019 Oct 26;24(21). Epub 2019 Oct 26.

Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.

A new group of arsenic(III) complexes with bidentate S,S-donor ligands, 1,2-benzenedithiol (Ph(SH)) and toluene-3,4-dithiol (MePh(SH)), were synthesized. The use of arsenic(III) iodide and bromide promoted the formation of neutral complexes (-) with the general formula AsX(LS) (X = I or Br, L = MePh or Ph). The crystal structures of these compounds were determined using single-crystal X-ray diffraction (scXRD). Read More

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http://dx.doi.org/10.3390/molecules24213865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864545PMC
October 2019

Nitroaromatic compounds damage the DNA of zebrafish embryos (Danio rerio).

Aquat Toxicol 2019 Dec 1;217:105345. Epub 2019 Nov 1.

Thünen-Institute of Fisheries Ecology, Herwigstraße 31, 27572, Bremerhaven, Germany.

Lethal and sublethal effects of trinitrotoluene (TNT) and its degradation products 2-amino-4,6-dinitrotoluene (2-ADNT) and 4-amino-2,6-dinitrotoluene (4-ADNT) to zebrafish embryos (Danio rerio) were investigated in a 120 h exposure scenario. Lethal concentrations (LC50) were 4.5 mg/l for TNT, 13. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.105345DOI Listing
December 2019

The emission characteristic of VOCs and the toxicity of BTEX from different mosquito-repellent incenses.

J Hazard Mater 2020 02 12;384:121428. Epub 2019 Oct 12.

School of Energy and Environmental Engineering, Tianjin Key Laboratory of Energy Utilization and Pollutant Control, Hebei University of Technology, Tianjin 300401, China.

Three types of mosquito-repellent incenses including disc, electric liquid and electric mat, were selected to investigate the emission of volatile organic compounds in the respiratory zone during the burning. VOCs were analyzed by GC-MS. Results showed that the average concentration of TVOCs released by using the disc, electric liquid and electric mat mosquito repellent incense types were 7. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.121428DOI Listing
February 2020

Airborne toluene exposure causes germline apoptosis and neuronal damage that promotes neurobehavioural changes in Caenorhabditis elegans.

Environ Pollut 2020 Jan 16;256:113406. Epub 2019 Oct 16.

Programa de Pós-Graduação em Bioquímica, Grupo de pesquisa em Bioquímica e Toxicologia em Caenorhabditis elegans (GBToxCe), Universidade Federal do Pampa, Uruguaiana, RS, 97500-970, Brazil. Electronic address:

Toluene is a highly volatile organic solvent present in gasoline. Exposure mainly occurs by absorption via the pulmonary tract and easily reaches the central nervous system, which causes toxic effects. Toluene toxicity has been described but not well established. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.113406DOI Listing
January 2020

Neuropsychological effects among workers exposed to organic solvents.

Salud Publica Mex 2019 Sep-Oct;61(5):670-677

Unit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet. Stockholm, Sweden.

Objective: To assess neuropsychological performance among workers at a paint factory in Mexico City.

Materials And Methods: During 2004 and 2005 we assessed the neuropsychological performance of 208 workers who were exposed to organic solvents at a paint factory, mainly toluene and xylene. We categorized workers into low and high exposure groups using a cumulative index for toluene, based on times spent in different tasks. Read More

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http://dx.doi.org/10.21149/9800DOI Listing

Evaluating potential human health risks from modeled inhalation exposures to volatile organic compounds emitted from oil and gas operations.

J Air Waste Manag Assoc 2019 12 7;69(12):1503-1524. Epub 2019 Nov 7.

ICF, San Francisco, CA, USA.

Some states and localities restrict siting of new oil and gas (O&G) wells relative to public areas. Colorado includes a 500-foot exception zone for building units, but it is unclear if that sufficiently protects public health from air emissions from O&G operations. To support reviews of setback requirements, this research examines potential health risks from volatile organic compounds (VOCs) released during O&G operations. Read More

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http://dx.doi.org/10.1080/10962247.2019.1680459DOI Listing
December 2019
1 Read

Antineoplastic properties of zafirlukast against hepatocellular carcinoma via activation of mitochondrial mediated apoptosis.

Regul Toxicol Pharmacol 2019 Dec 9;109:104489. Epub 2019 Oct 9.

Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raibareli Road, Lucknow, 226025, India. Electronic address:

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwideand haslimited treatment options. In view of this, zafirlukast (ZAF) was administered orally to DEN-induced HCC rats to evaluate its antineoplastic properties. ELISA, qRT-PCR and Western blot were used to determine the molecular mechanism associated with ZAF therapy for HCC. Read More

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http://dx.doi.org/10.1016/j.yrtph.2019.104489DOI Listing
December 2019
2.031 Impact Factor

Prophylactic efficacy of Boerhavia diffusa L. aqueous extract in toluene induced reproductive and developmental toxicity in Drosophila melanogaster.

J Infect Public Health 2020 Feb 30;13(2):177-185. Epub 2019 Sep 30.

Department of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Cheonan, Republic of Korea. Electronic address:

Background: Environmental exposure to toxicants poses high risk to develop reproductive and developmental chronic toxicity in man. Toluene is one of the commonest industrial agents whose exposure is attributed with potential to induce reproductive and developmental toxicity. Since they contaminate the immediate environment of air and water to which humans are exposed, its containment is of great public health importance. Read More

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http://dx.doi.org/10.1016/j.jiph.2019.07.020DOI Listing
February 2020
1 Read

Evaluation of dimethyl sulfoxide (DMSO) as a co-solvent for toxicity testing of hydrophobic organic compounds.

Ecotoxicology 2019 Nov 26;28(9):1136-1141. Epub 2019 Sep 26.

Department of Plant and Environmental Sciences, University of Copenhagen, Thorvaldsensvej 40, 1871, Frederiksberg, Denmark.

Toxicity testing of hydrophobic compounds with low aqueous solubility remains challenging. Dimethyl sulfoxide (DMSO) is widely used as a co-solvent for toxicity testing of hydrophobic chemicals, but it may modulate chemical toxicity patterns. In this study, we critically evaluated the suitability of DMSO as a co-solvent for toxicity testing of hydrophobic organic compounds in aqueous solutions. Read More

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http://dx.doi.org/10.1007/s10646-019-02107-0DOI Listing
November 2019
1 Read

Effective extrapolation models for ecotoxicity of benzene, toluene, ethylbenzene, and xylene (BTEX).

Chemosphere 2020 Feb 18;240:124906. Epub 2019 Sep 18.

Power China of Beijing Engineering Corporation Limited, Beijing, 100024, PR China.

Benzene homologues have significant toxic effects to aquatic organisms. In this study, the acute toxicity data of benzene, toluene, ethylbenzene and xylene (BTEX) were collected and screened, and the toxicity extrapolation model of paired BTEX was established. The results showed that except the correlation between benzene and xylene was not strong due to insufficient data, the linear correlation of the other five paired BTEX was good (p < 0. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.124906DOI Listing
February 2020
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Exposure to BTEX in buses: The influence of vehicle fuel type.

Environ Pollut 2019 Dec 31;255(Pt 1):113100. Epub 2019 Aug 31.

FP-ENAS - UFP Energy, Environment and Health Research Unit, University Fernando Pessoa, Porto, Portugal; Faculty of Science and Technology, University Fernando Pessoa, Porto, Portugal.

Diesel-fueled buses have been replaced by Compressed Natural Gas (CNG) to minimize the high level of emissions in urban areas. However, differences in indoor exposure levels to Benzene, Toluene, Ethylbenzene and Xylene (BTEX) in those vehicles have not been investigated so far. The primary aim of this study was to determine if passengers are exposed to different BTEX levels when using buses powered by CNG or by diesel, and further explore if indoor levels are influenced by external air quality. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.113100DOI Listing
December 2019
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A novel array of double dielectric barrier discharge combined with TiCo catalyst to remove high-flow-rate toluene: Performance evaluation and mechanism analysis.

Sci Total Environ 2019 Nov 20;692:940-951. Epub 2019 Jul 20.

Environmental Engineering and Science Program, Department of Chemical and Environmental Engineering (ChEE), University of Cincinnati, Cincinnati, OH 45221-0012, USA. Electronic address:

A novel array double dielectric barrier discharge (ADDBD) combined with a TiO/AlO-CoO/AC (TiCo) catalyst was applied to remove toluene. The effects of catalyst setting distance, catalyst combination mode, and process factors (including specific input energy, initial toluene concentration, and relative humidity) were investigated in terms of the toluene degradation efficiency (η) and the selectivity of CO (S). When the specific input energy was 65 J·L, the initial toluene concentration was 100 mg·m, and the relative humidity was 30%, the highest η of 72% and S of 44% could be achieved with TiO/AlO 10 cm and CoO/AC 20 cm downstream of the ADDBD. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.07.318DOI Listing
November 2019
4 Reads

Concentration × time analyses of sensory irritants revisited: Weight of evidence or the toxic load approach. That is the question.

Authors:
Juergen Pauluhn

Toxicol Lett 2019 Nov 6;316:94-108. Epub 2019 Sep 6.

Hanover Medical School, Hannover, Germany; Bayer HealthCare, Wuppertal, Germany (retired). Electronic address:

The toxic effects resulting from inhalation exposure depend on both the concentration (C) of the inhaled substance and the exposure duration (t), including the assumptions that the exposure-limiting toxic effect is linearly linked with the accumulated C × t (inhaled dose), and detoxification or compensatory responses diminishing this dose are negligible. This interrelationship applies for both constant and fluctuating concentrations and is usually expressed by the toxic load equation C × t = constant effect (k). The toxic load exponent 'n' is derived from both C- and t-dependent exponents with C×t = k with n = b/b. Read More

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http://dx.doi.org/10.1016/j.toxlet.2019.09.001DOI Listing
November 2019
1 Read

Toluene Toxicity: A Case Report of Transdermal Exposure Causing Hypokalemic Paralysis.

Can J Kidney Health Dis 2019 27;6:2054358119871594. Epub 2019 Aug 27.

Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.

Rationale: Hypokalemia is a common finding. Typically asymptomatic presentations of neuromuscular weakness emerge at levels below 2.5 mmol/L. Read More

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http://dx.doi.org/10.1177/2054358119871594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713954PMC
August 2019
2 Reads

Toluene toxicity presenting with hypokalemia, profound weakness and U waves in the electrocardiogram.

Am J Emerg Med 2019 11 27;37(11):2120.e1-2120.e3. Epub 2019 Aug 27.

Echocardiography Laboratory, Cardiology Service, Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.

We present the case of a 25-year-old man with progressive limb weakness. His electrocardiogram showed prominent U waves which made us consider hypokalemia. The final diagnosis was toluene intoxication with severe hypokalemia and metabolic acidosis. Read More

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http://dx.doi.org/10.1016/j.ajem.2019.158417DOI Listing
November 2019
1 Read

Biodegradation of Atrazine by the Novel Strain FH-1.

Biomed Res Int 2019 28;2019:4756579. Epub 2019 Jul 28.

School of Science and Technology, Georgia Gwinnett College, Lawrenceville, GA, USA.

Bacterial strain FH-1 with high efficiency of degrading Atrazine is separated by means of enrichment culture from the soil applied with Atrazine for many years. FH-1, recognized as based on phylogenetic analysis of 16S rDNA sequences, can grow with Atrazine which is the sole nitrogen source. In fluid inorganic salt medium, the optimal degradation temperature, pH value, and initial concentration of Atrazine are 25°C, 9. Read More

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http://dx.doi.org/10.1155/2019/4756579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699352PMC
January 2020
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Catalytic oxidation of toluene, ethyl acetate and chlorobenzene over Ag/MnO-cordierite molded catalyst.

Sci Rep 2019 Aug 21;9(1):12162. Epub 2019 Aug 21.

College of Chemical and Environmental Engineering, Shandong University of Science and Technology, Qingdao, Shandong, 266590, P.R. China.

Multi-structured Ag/MnO-cordierite molded catalysts were prepared by hydrothermal method and applied to the catalytic oxidation of VOCs. Catalytic activities of Ag/MnO-cordierite were evaluated by 1000 ppm of toluene, ethyl acetate and chlorobenzene degradation respectively at the air atmosphere, and their physicochemical properties were characterized through multiple techniques containing XRD, SEM, TEM, H-TPR and XPS. It is found that nanorod Ag/MnO-cordierite molded catalyst showed prominent catalytic activity for VOCs decomposition and the T for toluene, ethyl acetate and chlorobenzene are 275 °C, 217 °C and 385 °C respectively under the space velocity of 10,000 h. Read More

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http://dx.doi.org/10.1038/s41598-019-48506-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704122PMC
August 2019
2 Reads

Acute exposure to the water-soluble fraction of gasoline (WSF) affects oxygen consumption, nitrogenous-waste and Mg excretion, and activates anaerobic metabolism in the goldfish Carassius auratus.

Comp Biochem Physiol C Toxicol Pharmacol 2019 Dec 9;226:108590. Epub 2019 Aug 9.

Department of Zoology, University of British Columbia, Vancouver, BC ZIP V6T 1Z4, Canada. Electronic address:

Contamination of aquatic environments by petroleum and its products (e.g. gasoline) is a hazard for aquatic organisms as a result of the potential toxicity of monocyclic aromatic hydrocarbons (BTEX) and polycyclic aromatic hydrocarbons (PAH). Read More

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http://dx.doi.org/10.1016/j.cbpc.2019.108590DOI Listing
December 2019
7 Reads

BTEX compositions and its potential health impacts in Malaysia.

Chemosphere 2019 Dec 27;237:124451. Epub 2019 Jul 27.

Environmental Research Group, School of Marine and Environmental Sciences, Universiti Malaysia Terengganu, 21030, Kuala Terengganu, Terengganu, Malaysia.

This study aims to determine the composition of BTEX (benzene, toluene, ethylbenzene and xylene) and assess the risk to health at different sites in Malaysia. Continuous monitoring of BTEX in Kuala Lumpur City Centre, Kuala Terengganu, Kota Kinabalu and Fraser Hill were conducted using Online Gas Chromatograph. For comparison, BTEX at selected hotspot locations were determined by active sampling method using sorbent tubes and Thermal Desorption Gas Chromatography Mass Spectrometry. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.124451DOI Listing
December 2019

The effect of adolescent inhalant abuse on energy balance and growth.

Pharmacol Res Perspect 2019 08 30;7(4):e00498. Epub 2019 Jul 30.

Florey Institute of Neuroscience and Mental Health Parkville VIC.

The abuse of volatile solvents such as toluene is a significant public health concern, predominantly affecting adolescents. To date, inhalant abuse research has primarily focused on the central nervous system; however, inhalants also exert effects on other organ systems and processes, including metabolic function and energy balance. Adolescent inhalant abuse is characterized by a negative energy balance phenotype, with the peak period of abuse overlapping with the adolescent growth spurt. Read More

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http://dx.doi.org/10.1002/prp2.498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664821PMC
August 2019
2 Reads

Release of Munitions Constituents in Aquatic Environments Under Realistic Scenarios and Validation of Polar Organic Chemical Integrative Samplers for Monitoring.

Environ Toxicol Chem 2019 11 3;38(11):2383-2391. Epub 2019 Oct 3.

US Navy Space and Naval Warfare Systems Center Pacific, San Diego, California.

Munitions constituents (MC) may be released into aquatic environments as a result of underwater military munitions (UWMM) corrosion and breach. The present study investigated the release of 2,4,6-trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) from Composition B fragments under 2 realistic exposure scenarios in a large flume with flow set at 15 cm/s: the first represented the release of MC from fully exposed Composition B, and the second represented release through a small hole, simulating a breached munition. Release of MC through a small hole was approximately 10 times lower than from exposed Composition B, demonstrating the strong influence of exposure to flow on release. Read More

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http://dx.doi.org/10.1002/etc.4553DOI Listing
November 2019
2 Reads

Benchmark dose assessment for coke oven emissions-induced telomere length effects in occupationally exposed workers in China.

Ecotoxicol Environ Saf 2019 Oct 23;182:109453. Epub 2019 Jul 23.

Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, China. Electronic address:

Telomeres are DNA-protein structures that protect chromosome ends from degradation and fusion, which are shortened by oxidative stress, for example air pollution including benzene, toluene, Coke Oven Emissions (COEs), and so on. As a biomarker of health and disease, telomere length is associated with cardiovascular, diabetes and cancers. The aim of this study was to estimate the effects of COEs exposure on telomere length and the benchmark dose (BMD) of COEs. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.109453DOI Listing
October 2019
2 Reads
2.762 Impact Factor

Toluene degradation via a unique metabolic route in indigenous bacterial species.

Arch Microbiol 2019 Dec 22;201(10):1369-1383. Epub 2019 Jul 22.

Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.

Tanneries are the primary source of toluene pollution in the environment and toluene due to its hazardous effects has been categorized as persistent organic pollutant. Present study was initiated to trace out metabolic fingerprints of three toluene-degrading bacteria isolated from tannery effluents of Southern Punjab. Using selective enrichment and serial dilution methods followed by biochemical, molecular and antibiotic resistance analysis, isolated bacteria were subjected to metabolomics analysis. Read More

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http://dx.doi.org/10.1007/s00203-019-01705-0DOI Listing
December 2019
2 Reads

Ionic liquid-based water treatment technologies for organic pollutants: Current status and future prospects of ionic liquid mediated technologies.

Sci Total Environ 2019 Nov 29;690:604-619. Epub 2019 Jun 29.

Department of Green Chemistry, School of Engineering Science, Lappeenranta-Lahti University of Technology, Sammonkatu 12, FI-50130 Mikkeli, Finland.

Water scarcity motivated the scientific researcher to develop efficient technologies for the wastewater treatment for its reuse. Ionic liquids have been applied to many industrial and analytical separation processes, but their applications in the wastewater treatment, especially in the removal of organic pollutants, are still not well explored. Potential applications of ionic liquids include solvent extraction, solvent membrane technologies and ionic liquid-modified materials that are mainly used as adsorbents. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.06.421DOI Listing
November 2019
9 Reads

Pesticide and trace element residues in honey and beeswax combs from Israel in association with human risk assessment and honey adulteration.

Food Chem 2019 Nov 4;299:125123. Epub 2019 Jul 4.

Department of Food Quality & Safety, Institute for Postharvest and Food Sciences, Agricultural Research Organization, Volcani Center, Rishon Letzion 7528809, Israel. Electronic address:

Beehive products are considered sentinels for environmental pollutants. The presence of trace elements and pesticides in honey and beeswax may pose a health hazard to consumers. The study's aim was to determine the profile of pesticides and trace elements in Israeli honey and beeswax samples in relation to human risk assessment. Read More

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http://dx.doi.org/10.1016/j.foodchem.2019.125123DOI Listing
November 2019