Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis: Manifestations of antiandrogenic and other modes of toxicity.
Aquat Toxicol 2018 Apr 3;199:240-251. Epub 2018 Apr 3.
US EPA Mid-Continent Ecology Division, 6201 Congdon Blvd, Duluth, MN, 55804, USA. Electronic address:
The Larval Amphibian Growth and Development Assay (LAGDA) is an internationally harmonized testing guideline for evaluating effects of chronic chemical exposure in amphibians. In order to evaluate the effects of chronic exposure to an antiandrogenic chemical in an amphibian model, prochloraz was tested using a variation of the LAGDA design. Exposure was initiated with <1d post-fertilization embryos at nominal concentrations of 0, 6. Read More