1,865 results match your criteria Toxicity Shellfish


Astilbin attenuates apoptosis induced by cadmium through oxidative stress in carp (Cyprinus carpio L.) head kidney lymphocyte.

Fish Shellfish Immunol 2022 May 13. Epub 2022 May 13.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, PR China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, China. Electronic address:

As a kind of environmental pollutant, heavy metal Cadmium (Cd) exists widely in the environment. It is well known that Cd can accumulate and cause damage in liver, kidney and other organs. However, there are few studies on the immune cytotoxicity of Cd to fish. Read More

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Evaluation of okadaic acid toxicity in human retinal cells and zebrafish retinas.

Toxicology 2022 May 13;473:153209. Epub 2022 May 13.

Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Glasgow G4 0BA, UK; School of Basic Medical Sciences, Shaoyang University, Shaoyang 422000, PR China. Electronic address:

Okadaic acid (OA, C₄₄H₆₈O₁₃) is a neurotoxin and phosphatase inhibitor produced by several dinoflagellate species. OA is widely known to accumulate in black sponges and is associated with seafood poisoning. Humans can be exposed to OA by consuming contaminated shellfish that have accumulated toxins during algal blooms. Read More

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Ratiometric fluorescent nanosystem based on upconversion nanoparticles for histamine determination in seafood.

Food Chem 2022 May 12;390:133194. Epub 2022 May 12.

College of Food Science and Engineering, Ocean University of China, Qingdao 266003, PR China. Electronic address:

Histamine is the prime culprit of toxicity resulting from seafood consumption, whereas conventional detection methods are not convenient to meet the needs of rapid histamine analysis nowadays. Based on upconversion nanoparticles (UCNPs) and inner filter effects (IFE), a novel ratiometric fluorescence nanosystem was developed for the efficient detection of histamine. Through pre-treatment with solid-phase extraction (SPE) and colorific azo coupling reaction of histamine, the fluorescence of UCNPs at 548 nm was quenched, while fluorescence at 664 nm was unchanged. Read More

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Sanguinarine attenuates hydrogen peroxide-induced toxicity in liver of Monopterus albus: Role of oxidative stress, inflammation and apoptosis.

Fish Shellfish Immunol 2022 May 13;125:190-199. Epub 2022 May 13.

Hunan Research Center of Engineering Technology for Utilization of Distinctive Aquatic Resource, Hunan Agricultural University, Changsha, 410128, China; Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha, 410128, China. Electronic address:

In aquatic animals, hydrogen peroxide (HO), which is a source of oxidative stress, can cause physiological dysfunction, inflammation, and death. Sanguinarine (SAN) is a plant extract known to improve antioxidant and immune capacity. However, the roles of SAN in HO-induced liver tissue toxicity is unclear. Read More

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Multi-biomarkers approach to assess the toxicity of novel insecticide (Voliam flexi®) on Clarias gariepinus: From behavior to immunotoxicity.

Fish Shellfish Immunol 2022 May 4;125:54-64. Epub 2022 May 4.

Department of Zoology, Faculty of Sciences, Assiut University, Assiut, 71516, Egypt. Electronic address:

This study was conducted to determine for the first time the immunological, histopathological, histochemical, and ultrastructural changes; hematological and biochemical alterations; and poikilocytosis induced in Clarias gariepinus by Voliam flexi® 40% WG (thiamethoxam + chlorantraniliprole). Beside control fish, juvenile C. gariepinus were subjected to three sublethal concentrations of Voliam flexi® (43. Read More

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Polystyrene nanoplastics induced cardiomyocyte apoptosis and myocardial inflammation in carp by promoting ROS production.

Fish Shellfish Immunol 2022 Apr 30;125:1-8. Epub 2022 Apr 30.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, PR China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, PR China. Electronic address:

Nanoplastics (NPs) existing in aquatic ecosystem is an emerging environmental pollutant, which has become a nagging serious environmental problem. Miniaturized plastic fragments with different diameters have different penetration capabilities to body tissues, and thus may have different toxicity to the target organs. However, the specific toxicological effects and mechanisms of NPs with different particle sizes on aquatic animal hearts are still unknown. Read More

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Toxicity response to benzo[α]pyrene exposure: Modulation of immune parameters of the bay scallop, Argopectenirradians.

Fish Shellfish Immunol 2022 May 27;124:505-512. Epub 2022 Apr 27.

Division of Marine BioScience, Korea Maritime and Ocean University, Busan, 49112, South Korea. Electronic address:

Bay scallops were exposed to four BaP concentrations (0.5, 1.0, 10 and 50 μg/L) for 72 h to elucidate their immune response. Read More

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Effects of benzo[a]pyrene exposure on oxidative stress and apoptosis of gill cells of Chlamys farreri in vitro.

Environ Toxicol Pharmacol 2022 Apr 25;93:103867. Epub 2022 Apr 25.

The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China. Electronic address:

As a common pollutant in marine environment, benzo[a]pyrene (B[a]P) has high toxicity to economic shellfish. In order to explore the mechanism of oxidative stress and apoptosis, the effects of 0, 2, 4, 8 μg/mL B[a]P on gill cells of C. farreri at 12 and 24 h were studied. Read More

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Doctor I Have an Iodine Allergy.

Ophthalmol Ther 2022 Jun 24;11(3):931-938. Epub 2022 Apr 24.

Department of Ophthalmology, Mayo School of Medicine, 4500 San Pablo Rd., Jacksonville, FL, 32224, USA.

Ophthalmologists frequently face patients who refuse asepsis protocols involving povidone-iodine (PI) due to claims of an allergy to iodine. Such patients usually base this claim on previous reactions to shellfish consumption or to imaging procedures that used iodine-based contrast agents. Allergy to iodine, however, is biologically impossible, and iodine deficiency causes severe developmental problems, including mental retardation. Read More

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Current Situation of Palytoxins and Cyclic Imines in Asia-Pacific Countries: Causative Phytoplankton Species and Seafood Poisoning.

Int J Environ Res Public Health 2022 04 18;19(8). Epub 2022 Apr 18.

Laboratory of Marine Bioresource Technology, Department of Marine Life Science, School of Marine Biomedical Sciences, Jeju National University, Jeju City 63243, Korea.

Among marine biotoxins, palytoxins (PlTXs) and cyclic imines (CIs), including spirolides, pinnatoxins, pteriatoxins, and gymnodimines, are not managed in many countries, such as the USA, European nations, and South Korea, because there are not enough poisoning cases or data for the limits on these biotoxins. In this article, we review unregulated marine biotoxins (e.g. Read More

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Enhanced mercury reduction in the South Atlantic Ocean during carbon remineralization.

Mar Pollut Bull 2022 May 9;178:113644. Epub 2022 Apr 9.

Department of Environmental Sciences, Jožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia; Jožef Stefan International Postgraduate School, Jamova cesta 39, 1000 Ljubljana, Slovenia.

Mercury (Hg) in seawater is subject to interconversions via (photo)chemical and (micro)biological processes that determine the extent of dissolved gaseous mercury (DGM) (re)emission and the production of monomethylmercury. We investigated Hg speciation in the South Atlantic Ocean on a GEOTRACES cruise along a 40°S section between December 2011 and January 2012 (354 samples collected at 24 stations from surface to 5250 m maximum depth). Using statistical analysis, concentrations of methylated mercury (MeHg, geometric mean 35. Read More

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Immunotoxicity pathway and mechanism of benzo[a]pyrene on hemocytes of Chlamys farreri in vitro.

Fish Shellfish Immunol 2022 May 9;124:208-218. Epub 2022 Apr 9.

The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, 266003, PR China.

Benzo[a]pyrene (B[a]P), a typical PAHs widely existing in the marine environment, has been extensively studied for its immunotoxicity due to its persistence and high toxicity. Nevertheless, the immunotoxicity mechanism remain incompletely understood. In this study, isolated hemocytes of Chlamys farreri were exposed at three concentrations of B[a]P (5, 10 and 15 μg/mL), and the effects of B[a]P on detoxification metabolism, signal transduction, humoral immune factors, exocytosis and phagocytosis relevant proteins and immune function at 0, 6, 12, 24 h were studied. Read More

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Interactions effects of nano-microplastics and heavy metals in hybrid snakehead (Channa maculata ♀ × Channa argus ♂).

Fish Shellfish Immunol 2022 May 2;124:74-81. Epub 2022 Apr 2.

Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou, 510642, China; Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou, 510642, China. Electronic address:

The interaction between microplastics and contaminants has potentially generated new undefined risks on animals and ecosystems, and nano-microplastics are considered to be more harmful than microplastics. This experiment investigated the interactions and effects of nano-microplastics with heavy metals cadmium in hybrid snakehead. Different concentrations of nano-microplastics 80 nm (50 μg/L and 500 μg/L) and Cd (50 μg/L) were used for exposure, and four sampling points were set for 24 h, 48 h, 96 h and clear-48 h. Read More

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Rising CO will increase toxicity of marine dinoflagellate Alexandrium minutum.

J Hazard Mater 2022 06 3;431:128627. Epub 2022 Mar 3.

CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.

Ocean acidification caused by increasing emission of carbon dioxide (CO) is expected to have profound impacts on marine ecological processes, including the formation and evolution of harmful algal blooms (HABs). We designed a set of experiments in the laboratory to examine the effects of increasing CO on the growth and toxicity of a toxic dinoflagellate Alexandrium minutum producing paralytic shellfish toxins (PSTs). It was found that high levels of CO (800 and 1200 ppm) significantly promoted the growth of A. Read More

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Revisiting the HPLC-FLD Method to Quantify Paralytic Shellfish Toxins: C3,4 Quantification and the First Steps towards Validation.

Toxins (Basel) 2022 02 27;14(3). Epub 2022 Feb 27.

Centre of Marine Sciences (CCMAR), University of Algarve (UAlg), Campus de Gambelas, 8005-139 Faro, Portugal.

Paralytic shellfish toxins (PSTs) are a large group of biotoxins that cause paralytic shellfish poisoning. Their appearance in natural waters and their ingestion by aquatic species have a huge socio-economic impact, whereby their monitoring is of the upmost relevance to minimize the consequences. For earlier detection and faster response/action by stakeholders, validation of adjusted analytical methods, particularly for lower concentration levels, is important. Read More

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February 2022

Current Trends and New Challenges in Marine Phycotoxins.

Mar Drugs 2022 Mar 8;20(3). Epub 2022 Mar 8.

Departamento de Farmacologia, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain.

Marine phycotoxins are a multiplicity of bioactive compounds which are produced by microalgae and bioaccumulate in the marine food web. Phycotoxins affect the ecosystem, pose a threat to human health, and have important economic effects on aquaculture and tourism worldwide. However, human health and food safety have been the primary concerns when considering the impacts of phycotoxins. Read More

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Optimization and Validation of a High Throughput UHPLC-MS/MS Method for Determination of the EU Regulated Lipophilic Marine Toxins and Occurrence in Fresh and Processed Shellfish.

Mar Drugs 2022 Feb 26;20(3). Epub 2022 Feb 26.

Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata, Via Manfredonia 20, 71121 Foggia, Italy.

Under the name of lipophilic marine toxins, there are included more than 1000 toxic secondary metabolites, produced by phytoplankton, with the common chemical property of lipophilicity. Due to toxicological effects and geographical distribution, in European legislation relevant compounds are regulated, and their determination is accomplished with the reference liquid chromatography-tandem mass spectrometry method. In this study a modified ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method has been developed for the identification and quantification of EU-regulated lipophilic toxins. Read More

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February 2022

NLRP3 inflammasome is involved in the mechanism of the mitigative effect of lycopene on sulfamethoxazole-induced inflammatory damage in grass carp kidneys.

Fish Shellfish Immunol 2022 Apr 18;123:348-357. Epub 2022 Mar 18.

College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, Heilongjiang, PR China. Electronic address:

Freshwater environmental antibiotic pollution is becoming more severe because of the irregular use of sulfonamide antibiotics. Sulfamethoxazole (SMZ) is a kind of antibiotic that can cause harm to the urinary systems of organisms. However, the toxic impacts of environment-related concentrations of antibiotics in fish have not been thoroughly studied. Read More

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Transcriptional expression analysis reveals multiple effects of nonylphenol exposure on scallop immune system.

Fish Shellfish Immunol 2022 Apr 17;123:290-297. Epub 2022 Mar 17.

School of Agriculture, Ludong University, Yantai, 264025, China. Electronic address:

Nonylphenol (NP) is an endocrine disruptor and environmental hormone representing alkylphenol compounds. Marine mollusks are an important source of protein for people worldwide. Many researchers have begun to study the effect of NP on marine mollusks immune system in view of its toxicity; however, the underlying molecular mechanisms require in-depth analysis. Read More

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Acute effects of antimony exposure on adult zebrafish (Danio rerio): From an oxidative stress and intestinal microbiota perspective.

Fish Shellfish Immunol 2022 Apr 24;123:1-9. Epub 2022 Feb 24.

Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, State Environmental Protection Key Laboratory of Food Chain Pollution Control, Beijing Technology and Business University, Beijing, 100048, China; College of Energy and Environmental Engineering, Hebei University of Engineering, Handan, 056038, China. Electronic address:

The rapid development of the textile industry has resulted in a large influx of wastewater production. The "national discharge standards of water pollutants for dyeing and finishing of textile industry (GB4287-2012)" stipulates that the discharge of total Sb from textile industry effluent must be < 0.10 mg/L, but it is difficult to meet the standard at present. Read More

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In vitro effects of cantharidin on gilthead seabream (Sparus aurata) head-kidney leucocytes.

Fish Shellfish Immunol 2022 Apr 24;123:20-35. Epub 2022 Feb 24.

Immunobiology for Aquaculture Group, Department of Cell Biology and Histology. Faculty of Biology, Campus Regional de Excelencia Internacional "Campus Mare Nostrum", University of Murcia, 30100, Murcia, Spain. Electronic address:

Cantharidin is a toxic vesicant terpene used in folk and traditional medicine due to its various therapeutic effects. Since there are no previous data on the effect of cantharidin in fish, this study aimed to investigate the in vitro related-inflammatory effects of cantharidin in gilthead seabream (Sparus aurata L.) head-kidney leucocytes (HKLs). Read More

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Saxitoxin Group Toxins Accumulation Induces Antioxidant Responses in Tissues of , , and during a Bloom of .

Antioxidants (Basel) 2022 Feb 15;11(2). Epub 2022 Feb 15.

Laboratory of Marine Toxins, Physiology and Biophysics Program, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago 8380000, Chile.

Saxitoxin (STX) group toxins consist of a set of analogues which are produced by harmful algal blooms (HABs). During a HAB, filter-feeding marine organisms accumulate the dinoflagellates and concentrate the toxins in the tissues. In this study, we analyze the changes in antioxidant enzymes and oxidative damage in the bivalves and , and the gastropod during a bloom of . Read More

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February 2022

Concentrations of Tetrodotoxin (TTX) and Its Analogue 4,9-Anhydro TTX in Different Tissues of the Silver-Cheeked Pufferfish (, Gmelin, 1789) Caught in the South-Eastern Mediterranean Sea, Lebanon.

Toxins (Basel) 2022 02 8;14(2). Epub 2022 Feb 8.

Laboratory of Plankton and Shellfish Toxicity, Institute of Oceanography and Fisheries, Šetalište Ivana Meštrovića 63, 21000 Split, Croatia.

Pufferfishes are among the best-known marine organisms that accumulate marine biotoxins such as Tetrodotoxin (TTX). In the Mediterranean Sea, the silver-cheeked toadfish is the most reported TTX-bearer, causing many fatal and non-fatal cases. In Lebanon, no previous studies have measured TTX levels although the possibility of TTX-poisoning is high since is caught in different sizes and can be mistaken with other small fishes. Read More

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February 2022

The Caspase Homologues in Scallop and Their Expression Responses to Toxic Dinoflagellates Exposure.

Toxins (Basel) 2022 01 31;14(2). Epub 2022 Jan 31.

MOE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China.

The cysteine aspartic acid-specific protease (caspase) family is distributed across vertebrates and invertebrates, and its members are involved in apoptosis and response to cellular stress. The Zhikong scallop () is a bivalve mollusc that is well adapted to complex marine environments, yet the diversity of caspase homologues and their expression patterns in the Zhikong scallop remain largely unknown. Here, we identified 30 caspase homologues in the genome of the Zhikong scallop and analysed their expression dynamics during all developmental stages and following exposure to paralytic shellfish toxins (PSTs). Read More

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January 2022

Lipophilic Toxins in Chile: History, Producers and Impacts.

Mar Drugs 2022 Feb 4;20(2). Epub 2022 Feb 4.

Centro Oceanográfico de Vigo (IEO, CSIC), Subida a Radio Faro 50, 36390 Vigo, Pontevedra, Spain.

A variety of microalgal species produce lipophilic toxins (LT) that are accumulated by filter-feeding bivalves. Their negative impacts on human health and shellfish exploitation are determined by toxic potential of the local strains and toxin biotransformations by exploited bivalve species. Chile has become, in a decade, the world's major exporter of mussels () and scallops () and has implemented toxin testing according to importing countries' demands. Read More

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February 2022

Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense.

Fish Shellfish Immunol 2022 Mar 16;122:419-425. Epub 2022 Feb 16.

Shanghai Fisheries Research Institute (Shanghai Fisheries Technology Promotion Station), Shanghai, 200433, China. Electronic address:

The widespread occurrence and accumulation of plastic waste have been globally recognized as a critical issue. However, few researches have evaluated the adverse effects of nanoplastics to freshwater organisms. Thus, here, the effects of polystyrene nanoplastics (PS-NP) on the physiological changes (i. Read More

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Bioaccumulation of arsenic and immunotoxic effect in white shrimp (Penaeus vannamei) exposed to trivalent arsenic.

Fish Shellfish Immunol 2022 Mar 16;122:376-385. Epub 2022 Feb 16.

Department of Aquaculture, National Taiwan Ocean University, No.2 Beining Road, Zhongzheng District, Keelung City, 202301, Taiwan. Electronic address:

Trivalent arsenic (As (III)) contamination in the marine environment can produce adverse effects in crustaceans. The present study investigated the chronic toxicity of As (III) in white shrimp (Penaeus vannamei) by analyzing the tissue bioaccumulation and non-specific immune responses. Shrimps were exposed to 0 (control), 50, 500, and 2500 μg/L of As (III) for 21 days. Read More

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Trophic transfer of copper decreases the condition index in Crassostrea gigas spat in concomitance with a change in the microalgal fatty acid profile and enhanced oyster energy demand.

Sci Total Environ 2022 Jun 15;824:153841. Epub 2022 Feb 15.

Ifremer, Laboratory of Ecotoxicology, 44311 Nantes cedex 03, France.

Due to new usages and sources, copper (Cu) concentrations are increasing in the Arcachon Basin, an important shellfish production area in France. In the present paper, the trophic transfer of Cu was studied between a microalga, Tetraselmis suecica, and Crassostrea gigas (Pacific oyster) spat. An experimental approach was developed to assess Cu exposure, transfer and toxicity on both phytoplankton and spat. Read More

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Assessment of potential human health risks in aquatic products based on the heavy metal hazard decision tree.

BMC Bioinformatics 2022 Feb 17;22(Suppl 5):620. Epub 2022 Feb 17.

Department of Food Science, National Taiwan Ocean University, Keelung City, 20224, Taiwan.

Background: Naturally existing and human-produced heavy metals are released into the environment and cannot be completely decomposed by microorganisms, but they continue to accumulate in water and sediments, causing organisms to be exposed to heavy metals.

Results: This study designs and proposes heavy metal hazard decision trees for aquatic products, which are divided into seven categories including pelagic fishes, inshore fishes, other fishes, crustaceans, shellfish, cephalopods, and algae. Based on these classifications, representative fresh and processed seafood products are at the root of the heavy metal hazard decision trees. Read More

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February 2022

Toxic effects of waterborne cadmium exposure on hematological parameters, oxidative stress, neurotoxicity, and heat shock protein 70 in juvenile olive flounder, Paralichthysolivaceus.

Fish Shellfish Immunol 2022 Mar 14;122:476-483. Epub 2022 Feb 14.

Sun Moon University, Department of Aquatic Life and Medical Science, Asan-si, South Korea. Electronic address:

Cadmium-induced toxicity can affect fish embryo development, ion homeostasis regulation, energy metabolism, maturation and growth, stress response, and immunity. However, studies on the toxic effects of cadmium exposure to aquatic animals, particularly olive flounder (Paralichthys olivaceus), are limited. In this study, juvenile P. Read More

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