Eur J Anaesthesiol 2016 May;33(5):356-60
From the Service d'Anesthesie Reanimation Chirurgicale, Hopitaux Universitaires, Strasbourg, France (PAD, JP, EN); IRCAD-EITS, Strasbourg, France (MD); Laboratoire de Physiologie EA 3072, Faculté de médecine, Strasbourg, France (BG); and Department of Anesthesiology, and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, USA (GPJ).
Background: Nitrous oxide (N2O) is still considered an important component of general anaesthesia. However, should gas embolisation occur as result of carbon dioxide (CO2) pneumoperitoneum, N2O may compromise safety, as the consequences of a gas embolus consisting of a combination of CO2 and N2O may be more severe than CO2 alone.
Objective: This experimental study was designed to compare the cardiopulmonary consequences of gas embolisation with a N2O/CO2 mixture, or CO2 alone. Read More