7,358 results match your criteria Toxicity Mercury


Proteome changes in methylmercury-exposed mouse primary cerebellar granule neurons and astrocytes.

Toxicol In Vitro 2019 Feb 15. Epub 2019 Feb 15.

Department of Biology, University of Ottawa, Canada. Electronic address:

Methylmercury (MeHg) is a neurotoxicant, with the cerebellum as the main target of toxicity; however, the toxic effects of MeHg on specific cell types remain unclear. Here, primary cerebellar granule neurons (CGNs) and cerebellar astrocytes were isolated and analyzed for total mercury accumulation, cellular reactive oxygen species (ROS) production, and whole-cell proteome expression after exposure to 0-10 μM MeHg for 24 h. Intracellular mercury and ROS levels showed dose-dependent increases. Read More

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http://dx.doi.org/10.1016/j.tiv.2019.02.013DOI Listing
February 2019

Oleanolic acid 3-glucoside, a synthetic oleanane-type saponin, alleviates methylmercury toxicity in vitro and in vivo.

Toxicology 2019 Feb 15. Epub 2019 Feb 15.

School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan. Electronic address:

Methylmercury (MeHg) is one of the most toxic environmental pollutants, presenting a serious health hazard worldwide. In this study, we examined the potential of derivatives of oleanolic acid (OA), such as OA 3-glucoside, OA 28-glucoside, and OA 3,28-diglucoside, to mitigate MeHg toxicity in vitro and in vivo. We found that OA 3-glucoside suppressed the cellular MeHg uptake by 63. Read More

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http://dx.doi.org/10.1016/j.tox.2019.02.006DOI Listing
February 2019

A multidimensional concept for mercury neuronal and sensory toxicity in fish - from toxicokinetics and biochemistry to morphometry and behavior.

Biochim Biophys Acta Gen Subj 2019 Feb 12. Epub 2019 Feb 12.

Department of Biology and CESAM, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address:

Background: Neuronal and sensory toxicity of mercury (Hg) compounds has been largely investigated in humans/mammals with a focus on public health, while research in fish is less prolific and dispersed by different species. Well-established premises for mammals have been governing fish research, but some contradictory findings suggest that knowledge translation between these animal groups needs prudence [e.g. Read More

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http://dx.doi.org/10.1016/j.bbagen.2019.01.020DOI Listing
February 2019
4.381 Impact Factor

Phosphonium-based Ionic Liquid Modified Activated Carbon from Mixed Recyclable Waste for Mercury(II) Uptake.

Molecules 2019 Feb 5;24(3). Epub 2019 Feb 5.

Advanced Materials Research Chair, Chemistry Department P. O. Box 2455, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

The contamination of water surfaces by mercury is a dangerous environmental problem due to its toxicity, which leads kidney damage. Activated carbon from mixed recyclable waste modified by phosphonium-based ionic liquid (IL-ACMRW) was therefore prepared and evaluated for Hg(II) remediation. The activated carbon used in this study was prepared from mixed waste, including cardboard, papers and palm wastes as cheap raw materials. Read More

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http://dx.doi.org/10.3390/molecules24030570DOI Listing
February 2019

Mercury accumulation, speciation, and temporal trends in Atlantic Stingrays (Hypanus sabinus).

Ecotoxicology 2019 Feb 13. Epub 2019 Feb 13.

Department of Biological Sciences and Advanced Environmental Research Institute, University of North Texas, Denton, TX, USA.

Mercury (Hg) deposited into aquatic sediments can be converted into the more toxic methylmercury (MeHg) by microbial activity. Atlantic stingrays (Hypanus sabinus) are an estuarine and nearshore species found in coastal regions of the western North Atlantic, occurring in multiple habitat types, and feeding mainly on benthic invertebrates. Mercury dynamics and speciation in stingrays have not been well examined. Read More

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http://link.springer.com/10.1007/s10646-018-02014-w
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http://dx.doi.org/10.1007/s10646-018-02014-wDOI Listing
February 2019
2 Reads

Heavy metal pollution and potential health risks of commercially available Chinese herbal medicines.

Sci Total Environ 2019 Feb 30;653:748-757. Epub 2018 Oct 30.

Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.

A survey was conducted to investigate the pollution and health risks of copper (Cu), cadmium (Cd), lead (Pb), arsenic (As), mercury (Hg) and zinc (Zn) in 60 Chinese herbal medicines (CHMs) collected from a market in Kunming City, Yunnan Province, China. Furthermore, eight CHMs (Cyathulae radix, Drynariae rhizoma, Peucedani radix, Homalomenae rhizoma, Dryopteris setosa, Polygonati rhizoma, Lilii bulbus, and Linderae radix) containing high Cd concentrations were selected to further analyse their Cd chemical forms. Additionally, the dissolution rates of six heavy metals in decoction liquid were also analysed for four CHMs (Typhonii rhizoma, Linderae radix, Homalomenae rhizoma, and Cyathulae radix), and the health risks of heavy metals in CHMs were evaluated. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.10.388DOI Listing
February 2019

Human Biological Monitoring of Mercury Through Hair Samples in China.

Bull Environ Contam Toxicol 2019 Feb 9. Epub 2019 Feb 9.

CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, and HKU-IHEP Joint Laboratory on Metallomics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China.

Mercury (Hg) is a global pollutant that affects environmental and human health. Considering the high toxicity of Hg, it is required to assess the exposure of Hg in human body for appropriate risk management. In this review paper, we summarized data obtained through regional and small-scaled human biomonitoring (HBM) program for Hg in hair samples in China, which can deliver scientific data to make decisions on environmental health policy. Read More

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http://dx.doi.org/10.1007/s00128-019-02563-8DOI Listing
February 2019
3 Reads

Species and correlations between selenium and mercury in fishpond ecosystems.

Water Environ Res 2019 Feb 8. Epub 2019 Feb 8.

Tianjin Key Laboratory of Marine Resources and Chemistry, Tianjin University of Science and Technology, Tianjin, China.

The chemical species and contents of selenium and mercury in water, sediments, and crucian carps collected from three wild and three aquaculture fishponds in Tianjin, China, were determined, and the interaction between selenium and mercury in water was also investigated by the calorimetry method. The results revealed that the average contents of total selenium (TSe) and total mercury (THg) in each item of the wild areas were higher than in those of the aquaculture areas, and significant differences (95% confidence) were presented for THg both in the sediments and crucian carps. The molar ratios between TSe and THg in all investigated fishponds were far higher than 1, indicating good protective effects of selenium on mercury toxicity. Read More

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http://doi.wiley.com/10.1002/wer.1029
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http://dx.doi.org/10.1002/wer.1029DOI Listing
February 2019
2 Reads

The relationship between mercury exposure and epigenetic alterations regarding human health, risk assessment and diagnostic strategies.

J Trace Elem Med Biol 2019 Mar 14;52:37-47. Epub 2018 Nov 14.

Toxicology and Diseases Group, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Exposure to the environmental toxicants poses a serious threat to human health. The extent of exposure and the development of diseases are interrelated with each other. Chronic exposure to mercury (Hg) increases the risk of developing serious human disorders from embryo to adulthood. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0946672X183046
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http://dx.doi.org/10.1016/j.jtemb.2018.11.006DOI Listing
March 2019
3 Reads
2.491 Impact Factor

Assessment of Potential Mercury Toxicity to Native Invertebrates in a High-Gradient Stream.

Integr Environ Assess Manag 2019 Feb 6. Epub 2019 Feb 6.

DuPont Corporate Remediation Group, 974 Centre Road, Wilmington, DE 19805.

This study evaluated potential effects of mercury (Hg) on benthic macroinvertebrates in the South River, VA. The study used a multiple lines of evidence approach, including spatially- and temporally-matched sediment chemistry, biological, and toxicological information (Sediment Quality Triad), exposure and effect analysis in bulk and interstitial sediment and interstitial water, and critical body residue analysis. 10-day Chironomus dilutus and Hyalella azteca toxicity tests established site-specific no effect concentrations (NOEC) at 18. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ieam.4133
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http://dx.doi.org/10.1002/ieam.4133DOI Listing
February 2019
3 Reads

Computer-aided design of microfluidic resistive network using circuit partition and CFD-based optimization and application in microalgae assessment for marine ecological toxicity.

Bioprocess Biosyst Eng 2019 Feb 4. Epub 2019 Feb 4.

Medical School, Dalian University, Dalian, 116622, China.

We present an automatic design process for microfluidic dilution network towards marine ecological toxicity assessment on microalgae. Based on the hydraulic-electric circuit analogy, we defined an abstract specification using computer-aided designing system. Several approaches, especially circuit partition, were applied to minimize design effort. Read More

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http://dx.doi.org/10.1007/s00449-019-02082-0DOI Listing
February 2019
3 Reads

Environmental Mercury Chemistry - In Silico.

Acc Chem Res 2019 Feb 28;52(2):379-388. Epub 2019 Jan 28.

Department of Chemistry , University of Manitoba , Winnipeg , MB Canada , R3T 2N2.

Mercury (Hg) is a global environmental contaminant. Major anthropogenic sources of Hg emission include gold mining and the burning of fossil fuels. Once deposited in aquatic environments, Hg can undergo redox reactions, form complexes with ligands, and adsorb onto particles. Read More

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http://pubs.acs.org/doi/10.1021/acs.accounts.8b00454
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http://dx.doi.org/10.1021/acs.accounts.8b00454DOI Listing
February 2019
7 Reads

Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae.

Metallomics 2019 Jan 28. Epub 2019 Jan 28.

Molecular and Environment Sciences Group, Department of Geological Sciences, University of Saskatchewan, 114 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada. and Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.

Mercury is one of the most toxic elements threatening the biosphere, with levels steadily rising due to both natural and human activities. Selenium is an essential micronutrient, required for normal development and functioning of many organisms. While selenium is known to counteract mercury's toxicity under some conditions, to date information about the mercury-selenium relationship is fragmented and often controversial. Read More

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http://xlink.rsc.org/?DOI=C8MT00315G
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http://dx.doi.org/10.1039/c8mt00315gDOI Listing
January 2019
2 Reads

Metagenomic Evidence for a Species Capable of Bioremediation of Diverse Heavy Metals.

Front Microbiol 2018 9;9:3297. Epub 2019 Jan 9.

College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, China.

Heavy metal pollution has become an increasingly serious problem worldwide. Co-contamination with toxic mercury (Hg) and arsenic (As) presents a particularly difficult bioremediation trouble. By oxidizing the greenhouse gas methane, methanotrophs have been demonstrated to have high denitrification activity in eutrophic waters, indicating their possible potential for use in bioremediation of Hg(II) and As(V) in polluted water. Read More

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http://dx.doi.org/10.3389/fmicb.2018.03297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333641PMC
January 2019
3 Reads

Responses of Nonprotein Thiols to Stress of Vanadium and Mercury in Maize (Zea mays L.) Seedlings.

Bull Environ Contam Toxicol 2019 Jan 25. Epub 2019 Jan 25.

College of Chemistry and Bioengineering, Guilin University of Technology, Jiangan Road No.12, Guilin, 541004, Guangxi, China.

The heavy metal pollution in ecosystems is of increasing global concern. This study investigated firstly the responses of phytochelatins (PCs), glutathione (GSH) and other nonprotein thiols (NPT) in maize seedlings under vanadium (V), mercury (Hg) or their combined stress. With V or V-Hg combined stress, the contents of PCs, GSH and NPT in shoots and roots both increased with increasing the V stress level, and reached the maximum when the V stress level was 5 mg/L. Read More

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http://link.springer.com/10.1007/s00128-019-02553-w
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http://dx.doi.org/10.1007/s00128-019-02553-wDOI Listing
January 2019
4 Reads

Biological responses of the polychaete Hediste diversicolor (O.F.Müller, 1776) to inorganic mercury exposure: A multimarker approach.

Chemosphere 2019 Mar 10;219:989-996. Epub 2018 Dec 10.

ISPRA Italian National Institute for Environmental Protection and Research, Via di Castel Romano 100, 00128 Rome, Italy.

Mercury (Hg) is a global priority pollutant given its relevance in terms of environmental damage and threat to human health. Its ecotoxicity was tested using the benthic keystone species Hediste diversicolor as target species. After 10 days of exposure to different levels of inorganic Hg (10 and 50 μg L), bioaccumulation and a wide range of biological responses were evaluated at different biological levels, including biomarkers of exposure, neurotoxicity, oxidative stress, genotoxicity and cytochemistry. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00456535183238
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http://dx.doi.org/10.1016/j.chemosphere.2018.12.064DOI Listing
March 2019
3 Reads

Application of TDA AAS to Direct Mercury Determination in Postmortem Material in Forensic Toxicology Examinations.

J Anal Toxicol 2019 Jan 22. Epub 2019 Jan 22.

Department of Chemistry, Jagiellonian University, Gronostajowa 2, Krakow, Poland.

Mercury is a heavy metal with high toxicity, the level of which depends on the form of the metal. One of the newer techniques for determining trace amounts of total mercury in various materials, including biological samples, is thermal decomposition, amalgamation and atomic absorption spectrometry (TDA AAS). The TDA AAS method was optimized and validated using a mercury analyzer (DMA-80). Read More

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http://dx.doi.org/10.1093/jat/bky107DOI Listing
January 2019
1 Read

A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues.

Chem Commun (Camb) 2019 Feb;55(12):1766-1769

Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 120-750, Korea.

Owing to the extreme toxicity of mercury, methods for its selective and sensitive sensing in solutions, and in live cells and tissues are in great demand. In this study, we developed a naphthalimide-based diphenylphosphinothioyl group-containing fluorescent and colorimetric probe that selectively detects mercury (Hg2+). Upon addition of mercury (Hg2+) to a solution of the probe, both a colorimetric change from colorless to yellow and a fluorescence change from blue to green (under a 365 nm hand-held UV lamp) occur, both of which can be observed using the "naked-eye". Read More

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http://xlink.rsc.org/?DOI=C8CC08608G
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http://dx.doi.org/10.1039/c8cc08608gDOI Listing
February 2019
4 Reads
6.834 Impact Factor

Associations of blood mercury and fatty acid concentrations with blood mitochondrial DNA copy number in the Seychelles Child Development Nutrition Study.

Environ Int 2019 Mar 17;124:278-283. Epub 2019 Jan 17.

Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, 22185 Lund, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden. Electronic address:

Background: Fish contains methylmercury (MeHg) which can cause oxidative stress and neurodevelopmental toxicity at sufficiently high doses. Fish also contains polyunsaturated fatty acids (PUFA) which have both antioxidant (n-3) and oxidant (n-6) properties. Mitochondrial DNA (mtDNA) is sensitive to oxidative stress but has not been previously studied in relation to MeHg exposure or PUFA status. Read More

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http://dx.doi.org/10.1016/j.envint.2019.01.019DOI Listing
March 2019
2 Reads

Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay.

Biochim Biophys Acta Gen Subj 2019 Jan 16. Epub 2019 Jan 16.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, New York, USA.

Methylmercury (MeHg) is a toxic chemical compound naturally produced mainly in the aquatic environment through the methylation of inorganic mercury catalyzed by aquatic microorganisms. MeHg is biomagnified in the aquatic food chain and, consequently, piscivorous fish at the top of the food chain possess huge amounts of MeHg (at the ppm level). Some populations that have fish as main protein's source can be exposed to exceedingly high levels of MeHg and develop signs of toxicity. Read More

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http://dx.doi.org/10.1016/j.bbagen.2019.01.007DOI Listing
January 2019
2 Reads

Model for bioavailability and metal reduction from soil amended with petroleum wastewater by rye-grass L.

Int J Phytoremediation 2019 Jan 16:1-8. Epub 2019 Jan 16.

b Faculty of Civil Engineering and Earth Resources , University Malaysia Pahang (UMP) , Gambang , Malaysia.

To assess the tolerance, the rye-grass L. grown on soil amended with petroleum wastewater (PWW) containing four metals lead, zinc, nickel and mercury. The PWW (25 to 50%) showed remarkable increase in length and biomass. Read More

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http://dx.doi.org/10.1080/15226514.2018.1537243DOI Listing
January 2019
1 Read

Investigation of the differential transport mechanism of cinnabar and mercury containing compounds.

Environ Toxicol Pharmacol 2019 Feb 26;66:83-90. Epub 2018 Dec 26.

Joint International Research Laboratory of Ethnomedicine, Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical College, Guizhou, China. Electronic address:

Background: Cinnabar has a long history of uses in Chinese traditional medicines as an ingredient in various remedies. However, the detailed mechanism of cinnabar in medication remains unclear, and the toxicity of cinnabar has been a debate due to its containing mercury sulfide. This study was designed to investigate the differential transport mechanism of cinnabar and other Hg-containing compounds HgCl, MeHg and HgS, and to determine if organic anion transporters OAT1 and OAT3 were involved in the differential transport mechanism. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13826689183058
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http://dx.doi.org/10.1016/j.etap.2018.12.020DOI Listing
February 2019
7 Reads

Cadmium in plants: uptake, toxicity, and its interactions with selenium fertilizers.

Metallomics 2019 Jan 11. Epub 2019 Jan 11.

Key Laboratory of Arable Land Conservation (Middle and Lower Reaches of Yangtze River), Ministry of Agriculture, Research Center of Trace Elements, College of Resources and Environment, Huazhong Agricultural University, Wuhan 430070, China. and Hubei Provincial Engineering Laboratory for New-Type Fertilizers, Huazhong Agricultural University, Wuhan 430070, China.

Cd is the third major contaminant of greatest hazard to the environment after mercury and lead and is considered as the only metal that poses health risks to both humans and animals at plant tissue concentrations that are generally not phytotoxic. Cd accumulation in plant shoots depends on Cd entry through the roots, sequestration within root vacuoles, translocation in the xylem and phloem, and Cd dilution within the plant shoot throughout its growth. Several metal transporters, processes, and channels are involved from the first step of Cd reaching the root cells and until its final accumulation in the edible parts of the plant. Read More

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http://xlink.rsc.org/?DOI=C8MT00247A
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http://dx.doi.org/10.1039/c8mt00247aDOI Listing
January 2019
17 Reads

[Effects of Wetland Types on Distribution of Soil Methylmercury Based on the Region of Nanweng River in the Greater Xing'an Mountains].

Huan Jing Ke Xue 2018 Dec;39(12):5480-5486

College of Resources and Environment, Southwest University, Chongqing 400715, China.

Methylmercury (MeHg) is the most toxic organic matter of all mercury (Hg) compounds. Its toxicity is far higher than that of inorganic Hg. Methylmercury can enter the human body through food, threatening human health. Read More

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http://dx.doi.org/10.13227/j.hjkx.201805204DOI Listing
December 2018
1 Read

Comparison of Temperate and Tropical Freshwater Species' Acute Sensitivities to Chemicals: An Update.

Integr Environ Assess Manag 2019 Jan 9. Epub 2019 Jan 9.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China.

Toxicity data for tropical species are often lacking for deriving water quality guidelines (WQGs) and for conducting ecological risk assessment (ERA). To protect and safeguard valuable natural resources and important biodiversity in tropical freshwater ecosystems, a sound framework should be established to assess and manage the ecological risk of an ever-increasing number of chemicals that occur in the tropics. The present study aims to provide a more up-to-date comparison of the species sensitivity distributions (SSDs) between temperate and tropical freshwater species, by incorporating more acute toxicity data which have been documented. Read More

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http://dx.doi.org/10.1002/ieam.4122DOI Listing
January 2019
8 Reads

Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system.

Environ Sci Pollut Res Int 2019 Jan 5. Epub 2019 Jan 5.

Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, U.P., 202002, India.

Mercury is among the most toxic heavy metals and a widespread environmental pollutant. Mercury chloride (HgCl) is an inorganic compound of mercury which is easily absorbed in the gastrointestinal tract and then enters the blood where it can interact with erythrocytes. In this study, the effect of HgCl on human erythrocytes was studied under in vitro conditions. Read More

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http://dx.doi.org/10.1007/s11356-018-04062-5DOI Listing
January 2019
3 Reads

Prevalence of rheumatoid arthritis in relation to serum cadmium concentrations: cross-sectional study using Korean National Health and Nutrition Examination Survey (KNHANES) data.

BMJ Open 2019 Jan 3;9(1):e023233. Epub 2019 Jan 3.

Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

Objectives: It has been suggested that exposure to heavy metal cadmium (Cd) may contribute to a high risk of developing rheumatoid arthritis (RA). This study was to investigate the association of RA prevalence and serum concentrations of Cd and other heavy metals through large survey data analysis.

Design: A retrospective cross-sectional survey study. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326419PMC
January 2019
1 Read

Nitrogen-doped carbon dots rapid and selective detection of mercury ion and biothiol and construction of an IMPLICATION logic gate.

Talanta 2019 Mar 9;194:554-562. Epub 2018 Oct 9.

College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Central South University, Changsha 410083, Hunan, China. Electronic address:

Nitrogen-doped carbon dots (N-CDs) were prepared by adjusting the ratio of carbon sources (citric acid) and nitrogen sources (ethanolamine). This N-CDs fluorescent probe had been successfully applied to rapidly, sensitively and selectively determine the concentration of mercury ion (Hg) with a linear range of 0.1-5. Read More

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http://dx.doi.org/10.1016/j.talanta.2018.09.114DOI Listing
March 2019
1 Read

Concentration-dependent effects of mercury and lead on Aβ42: possible implications for Alzheimer's disease.

Eur Biophys J 2019 Jan 2. Epub 2019 Jan 2.

Department of Chemistry, University of Bari "Aldo Moro", via E. Orabona 4, 70126, Bari, Italy.

Mercury (Hg) and lead (Pb) are known to be toxic non-radioactive elements, with well-described neurotoxicology. Much evidence supports the implication of metals as potential risk cofactors in Alzheimer's disease (AD). Although the action mechanism of the two metals remains unclear, Hg and Pb toxicity in AD could depend on their ability to favour misfolding and aggregation of amyloid beta proteins (Aβs) that seem to have toxic properties, particularly in their aggregated state. Read More

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http://dx.doi.org/10.1007/s00249-018-1344-9DOI Listing
January 2019
2 Reads

Mercury and selenium levels, and Se:Hg molar ratios in freshwater fish from South Louisiana.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2019 Jan 2:1-8. Epub 2019 Jan 2.

c Department of Oceanography and Coastal Sciences , College of the Coast and Environment, Louisiana State University , Baton Rouge , Louisiana , USA.

Ample historical evidence has demonstrated the neurotoxicity of organic Hg. However, several studies have suggested that Se effectively sequesters MeHg. The affinity of Hg is up to ≈10 times higher for Se molecules than for comparable sulfur molecules, most of which are components of brain enzymes. Read More

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http://dx.doi.org/10.1080/10934529.2018.1546495DOI Listing
January 2019
1 Read

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium.

J Vis Exp 2018 Dec 17(142). Epub 2018 Dec 17.

Department of Biology, University of Ottawa;

Mercury (Hg) bioavailability to microbes is a key step to toxic Hg biomagnification in food webs. Cadmium (Cd) transformations and bioavailability to bacteria control the amount that will accumulate in staple food crops. The bioavailability of these metals is dependent on their speciation in solution, but more particularly under anoxic conditions where Hg is methylated to toxic monomethylmercury (MeHg) and Cd persists in the rhizosphere. Read More

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http://dx.doi.org/10.3791/58324DOI Listing
December 2018
1 Read

[Estimation of bioaccessibility and risk assessment of heavy metals in decoction pieces of Bupleuri Radix].

Zhongguo Zhong Yao Za Zhi 2018 Nov;43(22):4479-4485

Institute of Medicinal Plant Development, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100193, China.

This project was launched to study on the overall residual status of heavy metals of comprehensive understanding in decoction pieces of Bupleuri Radix (DPBR) from different habitats and risk assessment. In this study, inductively coupled plasma mass spectrometry was used to determine the heavy metals of 30 batches of Bupleuri Radix in different producing areas. Simulated gastrointestinal fluid method was used to determine the dissolution rate of heavy metals in the simulated gastrointestinal fluid and the average daily intake Average Daily Dose (ADD) and Hazard Quotient (HQ) index were used to assess the risk of heavy metals in DPBR. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20180724.002DOI Listing
November 2018
1 Read

Neurotoxic effects of mercury exposure in dental personnel.

Basic Clin Pharmacol Toxicol 2018 Dec 27. Epub 2018 Dec 27.

Biology Education Centre, Uppsala University, Uppsala, Sweden.

Numerous studies have reported neurobehavioural effects in dental personnel occupationally exposed to chronic low levels of mercury (Hg). Mercury exposure from dental work may also induce various chronic conditions such as elevation of amyloid protein expression, deterioration of microtubules, and increase or inhibition of transmitter release at motor nerve terminal endings. Therefore, clinical studies of Hg toxicity in dentistry may provide new knowledge about disturbed metal homeostasis in neurodegenerative diseases like Alzheimer's disease, multiple sclerosis and mood disorders. Read More

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http://dx.doi.org/10.1111/bcpt.13199DOI Listing
December 2018
1 Read
2.377 Impact Factor

Effects of geography and species variation on selenium and mercury molar ratios in Northeast Atlantic marine fish communities.

Sci Total Environ 2019 Feb 1;652:1482-1496. Epub 2018 Nov 1.

Institute of Marine Research, Bergen, Norway; Faculty of Mathematics and Natural Sciences, University of Bergen, Bergen, Norway.

Methylmercury (MeHg) is a potent neurotoxin that bioaccumulates in seafood. Co-occurrence of selenium (Se) may affect the bioavailability and toxicity of MeHg in organisms. Here we report the concentrations of total mercury (Hg) and Se in 17 teleost fish species (n = 8459) sampled during 2006-2015 from the North East Atlantic Ocean (NEAO) and evaluate species variation and effects of geography. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.10.405DOI Listing
February 2019
1 Read

Spatial and temporal distribution of total mercury in atmospheric wet precipitation at four sites from the Nepal-Himalayas.

Sci Total Environ 2019 Mar 23;655:1207-1217. Epub 2018 Nov 23.

Central Department of Hydrology and Meteorology, Tribhuvan University, Kathmandu, Nepal.

The studies on global pollutant mercury (Hg), which is of public concern due to its high toxicity and capacity to long-range transport via atmospheric circulation, is poorly characterized in wet deposition over the Nepal-Himalayas region. Therefore, in order to understand the concentration levels, spatial distribution and seasonal variation of total Hg, 333 precipitation samples were collected from south to north: Kathmandu (1314 m a.s. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.11.338DOI Listing
March 2019
2 Reads
4.099 Impact Factor

Hierarchically porous poly(ethylenimine) modified poly(styrene-co-divinylbenzene) microspheres for the adsorption of gold nanoparticles and simultaneously being transformed as the nanoparticles immobilized catalyst.

J Hazard Mater 2019 Mar 11;366:529-537. Epub 2018 Dec 11.

Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address:

With the extensive applications of gold nanoparticles (AuNPs) and the confirmation of their toxicity on human health and environment, it was urgent to remove AuNPs from environment. The hierarchically porous poly(ethylenimine) modified poly(styrene-co-divinylbenzene) microsphere (PEI-PS-DVB) was prepared and characterized by scanning electron microscopy, X-ray diffraction, transform infrared spectrometry, energy dispersive X-ray spectrometry, elemental analysis, contact angle, zeta potential analysis, N adsorption-desorption and mercury intrusion porosimetry. PEI-PS-DVB possessed abundant flow-through pores (70-120 nm) and meso/micropores (<50 nm); the former pores enabled full availability of the adsorbent to relatively large adsorbate, i. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2018.12.033DOI Listing
March 2019
3 Reads

Screening-level risk assessment of methylmercury for non-anadromous Arctic char (Salvelinus alpinus).

Environ Toxicol Chem 2018 Dec 18. Epub 2018 Dec 18.

Faculty of Agricultural and Environmental Sciences, McGill University, Montréal, Québec, Canada.

Non-anadromous forms of Arctic char (Salvelinus alpinus), those that are restricted to lakes and rivers, typically have higher mercury (Hg) concentrations than anadromous forms, which migrate to and from the sea. Using tissue burden data from the literature and our own analyses, we performed a screening-level risk assessment of methylmercury (MeHg) for non-anadromous Arctic char. Our assessment included 1569 fish distributed across 83 sites. Read More

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http://dx.doi.org/10.1002/etc.4341DOI Listing
December 2018
2 Reads

A Comparison of Mercury Exposure from Seafood Consumption and Dental Amalgam Fillings in People with and without Amyotrophic Lateral Sclerosis (ALS): An International Online Case-Control Study.

Int J Environ Res Public Health 2018 12 14;15(12). Epub 2018 Dec 14.

The Stacey Motor Neuron Disease Laboratory, Discipline of Pathology, Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, NSW 2050, Australia.

Exposures to toxic metals such as mercury have been suggested to be risk factors for amyotrophic lateral sclerosis (ALS). Human intake of mercury commonly occurs via consumption of seafood or from mercury-containing amalgam dental restorations ('mercury fillings'). We therefore compared mercury exposures from these sources in 401 ALS and 452 non-ALS respondents, using an internationally-available online questionnaire that asked respondents how often they ate seafood and what their favourite types of seafoods were. Read More

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http://dx.doi.org/10.3390/ijerph15122874DOI Listing
December 2018

Differential effects of nickel dosages on in vitro and in vivo seed germination and expression of a high affinity nickel-transport family protein (AT2G16800) in trembling aspen (Populus tremuloides).

Ecotoxicology 2019 Jan 14;28(1):92-102. Epub 2018 Dec 14.

Department of Biology, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.

It has been demonstrated that a number of metals including mercury (Hg), zinc (Zn), cadmium (Cd), cobalt (Co), lead (Pb), copper (Cu), and nickel (Ni) decrease seed germination rates and plant growth. The threshold levels of metal toxicity on seed germination, plant development, and gene regulation have not been studied in detail. The main objective of this study was to assess in vitro and in vivo the effects of different doses of nickel on Trembling aspen (Populus tremuloides) seed germination and regulation of the high affinity nickel transporter family protein (AT2G16800) gene. Read More

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http://dx.doi.org/10.1007/s10646-018-2003-8DOI Listing
January 2019
2 Reads

Renal toxicity of heavy metals (cadmium and mercury) and their amelioration with ascorbic acid in rabbits.

Environ Sci Pollut Res Int 2019 Feb 13;26(4):3909-3920. Epub 2018 Dec 13.

Department of Veterinary Biomedical Sciences, PMAS Arid Agriculture University, Rawalpindi, PK-46300, Pakistan.

Cadmium and mercury are among the most toxic and dangerous environmental pollutants that may cause fatal implications. Vitamin C is an important chain-breaking antioxidant and enzyme co-factor against heavy metals. The objective of the present study was to evaluate the toxicological effects of cadmium chloride, mercuric chloride, and their co-administration on biochemical parameters of blood serum and metal bioaccumulation in kidneys and also to elucidate the protective effect of vitamin C in rabbits against these metals. Read More

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http://dx.doi.org/10.1007/s11356-018-3819-8DOI Listing
February 2019
7 Reads
2.828 Impact Factor

Freshwater neotropical oligochaetes as native test species for the toxicity evaluation of cadmium, mercury and their mixtures.

Ecotoxicology 2018 Dec 13. Epub 2018 Dec 13.

Department of Ecology and Evolutionary Biology, Federal University of São Carlos, Rodovia Washington Luís, km 235, São Carlos, SP, 13565-905, Brazil.

The toxicity of metals, whether isolated or in mixtures, involves changes in biochemical processes as well as in cell membranes, which may lead to deleterious short- and long-term effects on the affected organisms. Among metals, cadmium and mercury stand out due to their abundance in nature, frequent use for industrial activities and biological accumulation, with high levels of residence in trophic chains. Benthic communities are particularly prone to metal pollution since metals usually accumulate in sediments. Read More

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http://dx.doi.org/10.1007/s10646-018-2006-5DOI Listing
December 2018
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An appraisal of properties of dental amalgam using commercially available and ayurvedically recycled mercury: Recycle and reuse.

J Conserv Dent 2018 Nov-Dec;21(6):651-656

Department of Mechanical Engineering, IIT, BHU, Varanasi, Uttar Pradesh, India.

Introduction: With the introduction of tooth-colored restoration material, the usage of amalgam has reduced over years. However, results regarding toxicity and health concerns are conflicting. Based on the concept of recycle and reuse, we previously used an ayurvedic method for purification of excess mercury obtained from dental operatory. Read More

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http://dx.doi.org/10.4103/JCD.JCD_114_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249937PMC
December 2018
2 Reads

Genetic, Reproductive and Hematological Toxicity Induced in Mice Exposed to Leachates from Petrol, Diesel and Kerosene Dispensing Sites.

J Health Pollut 2017 Dec 18;7(16):58-70. Epub 2017 Dec 18.

Department of Biology, Federal University of Technology, Akure, Ondo State, Nigeria.

Background: With a population of over 165,000,000, growing at an average rate of 2.7% per annum and an economic growth rate of about 5.7% in the past five years, the market for refined petroleum products in Nigeria is growing. Read More

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http://dx.doi.org/10.5696/2156-9614-7.16.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221447PMC
December 2017
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Oxidative and haemostatic effects of copper, manganese and mercury, alone and in combination at physiologically relevant levels: An ex vivo study.

Hum Exp Toxicol 2018 Dec 12:960327118818236. Epub 2018 Dec 12.

1 Department of Anatomy, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

Water contamination with metals due to anthropogenic activity is increasing and subsequent exposure increases the risk of associated toxicity. Exposure is not limited to a single metal but usually involves mixtures of different metals at different concentrations. Little is known about the contribution of this type of exposure, in humans, to the development of non-communicable diseases such as cardiovascular disease, and an increased risk to thrombosis. Read More

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http://dx.doi.org/10.1177/0960327118818236DOI Listing
December 2018
10 Reads

Immobilized bacterial biosensor for rapid and effective monitoring of acute toxicity in water.

Ecotoxicol Environ Saf 2019 Apr 6;170:205-209. Epub 2018 Dec 6.

Department of Pharmacy, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto 53123, Indonesia.

The use of biosensors by using microorganisms such as bacteria have short life cycles and provide other advantages. One colorimetric biosensor technique that has been developed is the use of a biosensor utilizing the incorporation of Prussian blue formation reactions mediated by E. coli bioreactors with ferricyanide. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2018.11.141DOI Listing
April 2019
3 Reads

Monomethylmercury degradation by the human gut microbiota is stimulated by protein amendments.

J Toxicol Sci 2018 ;43(12):717-725

Department of Biology, Faculty of Science, University of Ottawa, Ottawa, Canada K1N 9B4.

Monomethylmercury (MMHg) is a potent neurotoxicant that can be bioaccumulated and biomagnified through trophic levels. Human populations whose diets contain MMHg are at risk of MMHg toxicity. The gut microbiota was identified as a potential factor causing variation in MMHg absorption and body burden. Read More

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http://dx.doi.org/10.2131/jts.43.717DOI Listing
January 2019
1 Read

A coupled multivariate statistics, geostatistical and machine-learning approach to address soil pollution in a prototypical Hg-mining site in a natural reserve.

Chemosphere 2019 Mar 26;218:767-777. Epub 2018 Nov 26.

INDUROT and Environmental Technology, Biotechnology, and Geochemistry Group, Universidad de Oviedo, Campus de Mieres, 33600 Mieres, Asturias, Spain. Electronic address:

The impact of mining activities on the environment is vast. In this regard, many mines were operating well before the introduction of environmental law. This is particularly true of cinnabar mines, whose activity has declined for decades due to growing public concern regarding Hg high toxicity. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2018.11.172DOI Listing
March 2019
1 Read

Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway.

Neurotoxicology 2018 Nov 29;71:6-15. Epub 2018 Nov 29.

Division of Pharmacology, Department of Neuroscience, Reproductive and Dentistry Sciences, School of Medicine, "Federico II" University of Naples, Naples 80131, Italy; Division of Pharmacology, Department of Science and Technology, University of Sannio, 82100 Benevento, Italy. Electronic address:

In humans, mutation of glycine 93 to alanine of Cu/Zn superoxide dismutase type-1 (SOD1-G93 A) has been associated to some familial cases of Amyotrophic Lateral Sclerosis (ALS). Several evidence proposed the involvement of environmental pollutants that like mercury could accelerate ALS symptoms. SH-SY5Y cells stably transfected with SOD1 and G93 A mutant of SOD1 constructs were exposed to non-toxic concentrations (0. Read More

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http://dx.doi.org/10.1016/j.neuro.2018.11.009DOI Listing
November 2018
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Intestinal Methylation and Demethylation of Mercury.

Bull Environ Contam Toxicol 2018 Dec 4. Epub 2018 Dec 4.

CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, HKU-IHEP Joint Laboratory on Metallomics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China.

Mercury (Hg) is a global pollutant, which is linked with different diseases. The methylation of Hg and demethylation of methylmercury (MeHg) in the environment were extensively studied and summarized; however, the transformation of Hg in the intestine is less presented. In this review, the research progress and the perspectives on the intestinal transformation of Hg were discussed. Read More

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http://link.springer.com/10.1007/s00128-018-2512-4
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http://dx.doi.org/10.1007/s00128-018-2512-4DOI Listing
December 2018
6 Reads