8,196 results match your criteria Toxicity Mercury

Adipotropic effects of heavy metals and their potential role in obesity.

Fac Rev 2021 26;10:32. Epub 2021 Mar 26.

IM Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Epidemiological studies demonstrated an association between heavy metal exposure and the incidence of obesity and metabolic syndrome. However, the particular effects of metal toxicity on adipose tissue functioning are unclear. Therefore, recent findings of direct influence of heavy metals (mercury, cadmium, and lead) and metalloid (arsenic) on adipose tissue physiology are discussed while considering existing gaps and contradictions. Read More

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Investigation of the efficiency of BiOI/BiOCl composite photocatalysts using UV, cool and warm white LED light sources - Photon efficiency, toxicity, reusability, matrix effect, and energy consumption.

Chemosphere 2021 Apr 23;280:130636. Epub 2021 Apr 23.

Department of Inorganic and Analytical Chemistry, University of Szeged, H-6720, Szeged, Dóm tér 7, Hungary. Electronic address:

BiOI, BiOCl, and their composites (BiOI:BiOCl) with molar ratios from 95:5 to 5:95 were synthesized and tested in the transformation of methyl orange (MO) and sulfamethoxypyridazine (SMP) antibiotic, using three various LED light sources: UV LEDs (398 nm), cool and warm white LEDs (400-700 nm). The 80:20 BiOI:BiOCl photocatalyst showed the best adsorption capacity for MO and enhanced activity compared to BiOI and BiOCl. The apparent quantum yield (Φ) of the MO and SMP transformation for cool and warm white light was slightly lower than for 398 nm UV radiation. Read More

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Associations between blood heavy metal(loid)s and serum heme oxygenase-1 in pregnant women: Do their distribution patterns matter?

Environ Pollut 2021 Apr 29;286:117249. Epub 2021 Apr 29.

Institute of Reproductive and Child Health, Peking University/ Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Beijing, 100191, PR China; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, PR China.

The relationship between heavy metal(loid)s exposure and oxidative stress damage is a matter of research interest. Our study aimed to investigate the distribution patterns of the nine heavy metal(loid)s in blood of pregnant women, including four toxic heavy metal(loid)s [arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg)] and five typical heavy metal(loid)s [manganese (Mn), cobalt (Co), copper (Cu), zinc (Zn), and selenium (Se)] in blood. Blood samples of 348 women were collected and their concentrations in the serum (sr) and blood cells (bc) were measured, as well as serum heme oxygenase-1 (HO-1) (an oxidative stress marker). Read More

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Metals toxicity and its correlation with the gene expression in Alzheimer's disease.

Mol Biol Rep 2021 May 10. Epub 2021 May 10.

Geriatric Mental Health Department, KGMU, Lucknow, India.

Alzheimer's disease is a common neurodegenerative disease in the elderly population and a leading cause of dementia. Genetics and environmental risk factors were considered to play a major role in the onset of the disease. This study aimed to examine the correlation between different metals levels and the gene expression in Alzheimer's patients with age-matched control subjects. Read More

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Factors affecting mercury concentrations in two oceanic cephalopods of commercial interest from the southern Caribbean.

Mar Pollut Bull 2021 May 6;168:112408. Epub 2021 May 6.

Institute of Environment, Department of Biological Sciences, Florida International University, 3000 NE 151st, North Miami, FL 33181, USA.

Mercury (Hg) concentrations have significantly increased in oceans during the last century. This element accumulates in marine fauna and can reach toxic levels. Seafood consumption is the main pathway of methylmercury (MeHg) toxicity in humans. Read More

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Impact of dietary mercury intake during pregnancy on the health of neonates and children: a systematic review.

Nutr Rev 2021 May 5. Epub 2021 May 5.

S. Saavedra and J.D. Gonzalez-Sanz are with the Department of Nursing, University of Huelva, Huelva, Spain. Á. Fernández-Recamales, A. Sayago, and R. González-Domínguez are with the AgriFood Laboratory, Faculty of Experimental Sciences, University of Huelva, Huelva, Spain; and the Agrifood Campus of International Excellence (ceiA3), University of Huelva, Huelva, Spain. A. Cervera-Barajas is with the Department of Nursing, University of Seville, Seville, Spain.

Context: Growing evidence suggests that prenatal exposure to methyl mercury through the maternal diet could have great influence on the neurological and physical development of neonates and young children.

Objective: The aim of this review was to evaluate the clinical repercussions of maternal exposure to methyl mercury during pregnancy on the health of fetuses, neonates, and children up to 8 years of age.

Data Sources: The Web of Science, PubMed, CINAHL, Scopus, and Dialnet Plus databases were searched for articles published in English or Spanish from 1990 to 2020. Read More

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Effects of Low-dose Mercury Exposure in Newborns on mRNA Expression Profiles.

Bull Environ Contam Toxicol 2021 May 4. Epub 2021 May 4.

School of Public Health/Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, 550025, Guiyang, China.

This study was designed to investigate the molecular mechanism of mercury (Hg) toxicity in the newborns by mRNA sequencing (mRNA-seq). A questionnaire survey, routine blood parameters of pregnant women, and umbilical cord blood (UCB) of newborns were collected. The median (25th percentile, 75th percentile) of total Hg (THg) concentrations in UCB of newborns was 3. Read More

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Hg(II) Binding to Thymine Bases in DNA.

Inorg Chem 2021 May 3. Epub 2021 May 3.

Molecular and Environmental Sciences Group, Department of Geological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E2, Canada.

The compounds of mercury can be highly toxic and can interfere with a range of biological processes, although many aspects of the mechanism of toxicity are still obscure or unknown. One especially intriguing property of Hg(II) is its ability to bind DNA directly, making interstrand cross-links between thymine nucleobases in AT-rich sequences. We have used a combination of small molecule X-ray diffraction, X-ray spectroscopies, and computational chemistry to study the interactions of Hg(II) with thymine. Read More

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Projected near-future ocean acidification decreases mercury toxicity in marine copepods.

Environ Pollut 2021 Apr 23;284:117140. Epub 2021 Apr 23.

State Key Laboratory of Marine Environmental Science/College of the Environment & Ecology, Xiamen University, Xiamen, 361102, China.

Here, we examined the combinational effect of ocean acidification (OA) and mercury (Hg) in the planktonic copepod Pseudodiaptomus annandalei in cross-factored response to different pCO (400, 800 μatm) and Hg (control, 1.0 and 2.5 μg/L) exposures for three generations (F0-F2), followed by single-generation recovery (F3) under clean condition. Read More

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Metal-metal interaction and metal toxicity: a comparison between mammalian and .

Xenobiotica 2021 May 13:1-10. Epub 2021 May 13.

School of Life Sciences, Tianjin University, Tianjin, China.

1. Non-essential heavy metals such as mercury (Hg), arsenic (As), cadmium (Cd), and aluminium (Al) are useless to organisms and have shown extensive toxic effects. Previous studies show that two main molecular mechanisms of metal toxicity are oxidative stress and metal-metal interaction which can disrupt metal homeostasis. Read More

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An Environmentally Friendly, Photochemical Access to [N^C^N]Au(III) Pincer Complexes by Oxidative Addition.

Chemistry 2021 Apr 30. Epub 2021 Apr 30.

Ruprecht Karls Universitat Heidelberg, Organisch-Chemisches Institut, Im Neuenheimer Feld 270, 69120, Heidelberg, GERMANY.

Starting from commercially available DMSAuCl and diazonium salts, cationic [N^C^N]Au(III) complexes were synthesized in a selective, photosensitizer-free, photochemical reaction by irradiation with blue LED light. This new protocol represents the first easy synthesis of these types of pincer-complexes in moderate to excellent yield starting from a readily available gold(I) precursor with nitrogen as the only byproduct. Owing to the disadvantages of known protocols, especially the toxicity in case of a transmetallation with mercury or the necessity for a mostly twofold excess of a gold precursor, this method offers an attractive alternative towards this kind of gold(III) complexes. Read More

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Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic.

Front Pharmacol 2021 13;12:643972. Epub 2021 Apr 13.

Medical Toxicology and Drug Abuse Research Center, Birjand University of Medical Sciences, Birjand, Iran.

The industrial activities of the last century have caused massive increases in human exposure to heavy metals. Mercury, lead, chromium, cadmium, and arsenic have been the most common heavy metals that induced human poisonings. Here, we reviewed the mechanistic action of these heavy metals according to the available animal and human studies. Read More

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The Role of Toxic Metals and Metalloids in Nrf2 Signaling.

Antioxidants (Basel) 2021 Apr 21;10(5). Epub 2021 Apr 21.

Department of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University P.le Aldo Moro 5, 00185 Rome, Italy.

Nuclear factor erythroid 2-related factor 2 (Nrf2), an emerging regulator of cellular resistance to oxidants, serves as one of the key defensive factors against a range of pathological processes such as oxidative damage, carcinogenesis, as well as various harmful chemicals, including metals. An increase in human exposure to toxic metals via air, food, and water has been recently observed, which is mainly due to anthropogenic activities. The relationship between environmental exposure to heavy metals, particularly cadmium (Cd), lead (Pb), mercury (Hg), and nickel (Ni), as well as metaloid arsenic (As), and transition metal chromium (Cr), and the development of various human diseases has been extensively investigated. Read More

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Graphene Oxide-Based Nanofiltration for Hg Removal from Wastewater: A Mini Review.

Megawati Zunita

Membranes (Basel) 2021 Apr 8;11(4). Epub 2021 Apr 8.

Department of Chemical Engineering, Faculty of Industrial Technology, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia.

Mercury (Hg) is one of heavy metals with the highest toxicity and negative impact on the biological functions of living organisms. Therefore, many studies are devoted to solving the problem of Hg separation from wastewater. Membrane-based separation techniques have become more preferable in wastewater treatment area due to their ease of operation, mild conditions and also more resistant to toxic pollutants. Read More

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Adsorptivity of mercury on magnetite nano-particles and their influences on growth, economical, hemato-biochemical, histological parameters and bioaccumulation in Nile tilapia (Oreochromis niloticus).

Aquat Toxicol 2021 Jun 20;235:105828. Epub 2021 Apr 20.

Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Zagazig University, P.O. Box 44511, Zagazig, Sharkia, Egypt.

Among toxic pollutants, Mercury (Hg) is a toxic heavy metal that induces harmful impacts on aquatic ecosystems directly and human being's health indirectly. This study confirmed the in vitro magnetic potential of magnetite Nano-Particles (FeO NPs) against waterborne Hg exposure-induced toxicity in Nile tilapia (Oreochromis niloticus). We further evaluate the safety profile of FeO NPs on fish growth, hemato-biochemical, histological parameters, bioaccumulation in muscles, and economy. Read More

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Co-substrate-mediated utilization of high concentration of phenol by Aspergillus niger FP7 and reduction of its phytotoxicity on Vigna radiata L.

Environ Sci Pollut Res Int 2021 Apr 23. Epub 2021 Apr 23.

Department of Microbiology, School of Sciences, JAIN (Deemed-to-be University), 18/3, 9th Main, 3rd Block, Jayanagar, Bangalore, Karnataka, 560011, India.

Phenol and its derivatives behave as mutagens, teratogens and carcinogens inducing adverse physiological effects and are considered environmental hazards. The present study focuses on high concentration phenol utilization by Aspergillus niger FP7 under various physicochemical parameters. The soil remediation potential of the culture for reducing phenol toxicity against Vigna radiata L. Read More

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The Herbal Constituents in An-Gong-Niu-Huang Wan (AGNH) Protect against Cinnabar- and Realgar-Induced Hepatorenal Toxicity and Accumulations of Mercury and Arsenic in Mice.

Evid Based Complement Alternat Med 2021 1;2021:5566078. Epub 2021 Apr 1.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.

An-Gong-Niu-Huang Wan (AGNH) has been a well-known cinnabar- and realgar-containing compound recipe for cerebral diseases. Unfortunately, its clinical practice is often restrained by the specific hepatorenal toxicity of cinnabar and realgar (C + R). In previous research studies, we have found that the antioxidative and anti-inflammatory effects of its herbal constituents could mitigate the risks from the toxicity. Read More

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DNA-templated fluorescent silver nanoclusters on-off switch for specific and sensitive determination of organic mercury in seafood.

Biosens Bioelectron 2021 Jul 6;183:113217. Epub 2021 Apr 6.

Key Laboratory for Analytical Science of Food Safety and Biology of MOE, Fujian Provincial Key Lab of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China. Electronic address:

Organic mercury including methyl-mercury and ethyl-mercury (CHHg and CHHg) has high toxicity and bio-accumulation, and thus is easy to generate bio-amplification in food chain. Hence, the specific detection of organic mercury has great significance for objectively assessing the health risk of mercury in seafood. We herein designed an aptamer (A), which consists of a silver nanoclusters (AgNCs) scaffold sequence (A) and a T-rich sequence (A), for simultaneously synthetizing DNA-templated AgNCs and recognizing organic mercury, and further developed a label-free fluorescent method for the sensitive and specific determination of organic mercury (CHHg and CHHg total concentration) by using DNA-templated AgNCs as signal. Read More

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Trimetazidine Protects from Mercury-Induced Kidney Injury.

Pharmacology 2021 Apr 13:1-9. Epub 2021 Apr 13.

Pharmacology, Faculty of Biochemical and Pharmaceutical Sciences. National University of Rosario, CONICET, Rosario, Argentina.

Introduction: The presence of mercury in the environment is a worldwide concern. Inorganic mercury is present in industrial materials, is employed in medical devices, is widely used in batteries, is a component of fluorescent light bulbs, and it has been associated with human poisoning in gold mining areas. The nephrotoxicity induced by inorganic mercury is a relevant health problem mainly in developing countries. Read More

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Heavy metals multi-tolerant Bradyrhizobium isolated from mercury mining region in Algeria.

J Environ Manage 2021 Jul 8;289:112547. Epub 2021 Apr 8.

Laboratoire d'Ecologie Microbienne, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000 Bejaia, Algeria.

Heavy metals accumulation in the environment has led to a decrease in the capacity of ecosystems to sustain life as human, animal and plant health is threatened. To remedy this problem, rhizoremediation has been suggested as a solution. Legumes and rhizobia symbiotic association has captivated attention due to its involvement in the restoration of heavy-metal-contaminated sites. Read More

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Evaluation of heavy metal pollution in coastal sediments of Bandar Abbas, the Persian Gulf, Iran: Mercury pollution and environmental geochemical indices.

Mar Pollut Bull 2021 Apr 7;167:112314. Epub 2021 Apr 7.

Faculty of Chemistry, Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran 1651153311, Iran. Electronic address:

Mercury has been measured by using Cold Vapor-Atomic Absorption Spectrophotometry in coastal sediments of the Persian Gulf (Bandar Abbas region). The mean concentration of the six stations followed a decreasing order of S6 (3.95) > S1 (3. Read More

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Simultaneous enrichment of inorganic and organic species of lead and mercury in pg L levels by solid phase extraction online combined with high performance liquid chromatography and inductively coupled plasma mass spectrometry.

Anal Chim Acta 2021 May 13;1157:338388. Epub 2021 Mar 13.

College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, 311121, China; Key Laboratory of Organosilicon Chemistry and Material Technology, Hangzhou Normal University, Hangzhou, 311121, China. Electronic address:

Quantification of ultra-trace inorganic and organic species of lead and mercury in unpolluted environmental water is crucial to estimate the mobility, toxicity and bioavailability and interactions. Simultaneous pre-concentration of Pb and Hg species in pg L levels followed by multi-elemental speciation analysis makes great sense to a large set of unstable samples because of time advantages. Herein simultaneous enrichment and speciation analysis of ultra-trace lead and mercury in water was developed by online solid-phase extraction coupled with high performance liquid chromatography and inductively coupled plasma mass spectrometry (SPE-HPLC-ICP-MS) for this aim. Read More

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Mg,Si-Co-Substituted Hydroxyapatite/Alginate Composite Beads Loaded with Raloxifene for Potential Use in Bone Tissue Regeneration.

Int J Mol Sci 2021 Mar 13;22(6). Epub 2021 Mar 13.

Department of Analytical Chemistry, Chair of Analytical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, 02-097 Warsaw, Poland.

Osteoporosis is a worldwide chronic disease characterized by increasing bone fragility and fracture likelihood. In the treatment of bone defects, materials based on calcium phosphates (CaPs) are used due to their high resemblance to bone mineral, their non-toxicity, and their affinity to ionic modifications and increasing osteogenic properties. Moreover, CaPs, especially hydroxyapatite (HA), can be successfully used as a vehicle for local drug delivery. Read More

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Cellular and Molecular Mechanisms Mediating Methylmercury Neurotoxicity and Neuroinflammation.

Int J Mol Sci 2021 Mar 18;22(6). Epub 2021 Mar 18.

Institute for Clinical and Biomedical Research (iCBR), Center for Innovative Biomedicine and Biotechnology (CIBB), and Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.

Methylmercury (MeHg) toxicity is a major environmental concern. In the aquatic reservoir, MeHg bioaccumulates along the food chain until it is consumed by riverine populations. There has been much interest in the neurotoxicity of MeHg due to recent environmental disasters. Read More

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Phytoremediation and Microorganisms-Assisted Phytoremediation of Mercury-Contaminated Soils: Challenges and Perspectives.

Int J Environ Res Public Health 2021 03 2;18(5). Epub 2021 Mar 2.

Department of Molecular Biology and Biotechnology, Babeş-Bolyai University, 1 Kogălniceanu St., 400084 Cluj-Napoca, Romania.

Mercury (Hg) pollution is a global threat to human and environmental health because of its toxicity, mobility and long-term persistence. Although costly engineering-based technologies can be used to treat heavily Hg-contaminated areas, they are not suitable for decontaminating agricultural or extensively-polluted soils. Emerging phyto- and bioremediation strategies for decontaminating Hg-polluted soils generally involve low investment, simple operation, and application, and they are less destructive for the ecosystem. Read More

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The Prevalence of Inorganic Mercury in Human Kidneys Suggests a Role for Toxic Metals in Essential Hypertension.

Toxics 2021 Mar 21;9(3). Epub 2021 Mar 21.

Elemental Bio-Imaging Facility, School of Mathematical and Physical Sciences, University of Technology Sydney, Sydney 2007, Australia.

The kidney plays a dominant role in the pathogenesis of essential hypertension, but the initial pathogenic events in the kidney leading to hypertension are not known. Exposure to mercury has been linked to many diseases including hypertension in epidemiological and experimental studies, so we studied the distribution and prevalence of mercury in the human kidney. Paraffin sections of kidneys were available from 129 people ranging in age from 1 to 104 years who had forensic/coronial autopsies. Read More

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The Irrawaddy dolphin, Orcaella brevirostris from the Mekong river Cambodia: Preliminary health and toxicological investigations.

Aquat Toxicol 2021 May 21;234:105812. Epub 2021 Mar 21.

Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine Hannover, Werftstr. 6, 25761 Büsum, Germany.

The subpopulation of the Irrawaddy dolphin (Orcaella brevirostris) living in the Mekong River, Cambodia, is considered to be critically endangered. The aim of the investigation was to gain information about the genetic variation, health status and exposure to toxic compounds of these dolphins. Tissue samples from 27 Irrawaddy river dolphins found dead along the Mekong River between 2004 and 2009 were analysed with regards to genetics, pathology and ecotoxicology. Read More

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Mercury Concentrations in Big Brown Bats (Eptesicus fuscus) of the Finger Lakes Region, New York.

Arch Environ Contam Toxicol 2021 Apr 1. Epub 2021 Apr 1.

Department of Environmental Biology, State University of New York College of Environmental Science and Forestry, Syracuse, NY, 13210, USA.

The northeastern United States receives elevated mercury (Hg) deposition from United States and global emissions, making it critical to understand the fate of Hg in watersheds with a variety of aquatic habitats and land use types, such as the Finger Lakes region of New York State. Bats are valuable and important organisms to study chronic Hg exposure, because they are at risk of sublethal effects from elevated Hg exposure. The objectives of this study were to: (1) determine total Hg (THg) and methylmercury (MeHg) concentrations in big brown bats (Eptesicus fuscus) of the Finger Lakes region; (2) assess whether morphometric, temporal, or spatial factors predict bat Hg concentrations; and (3) investigate the role of trophic position and diet represented by stable isotopes of carbon and nitrogen in explaining variations in bat Hg concentrations. Read More

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How efficient is graphene-based nanocomposite to adsorb Hg from seawater. A laboratory assay to assess the toxicological impacts induced by remediated water towards marine bivalves.

Chemosphere 2021 Mar 6;277:130160. Epub 2021 Mar 6.

CESAM & Department of Biology, University of Aveiro, 3810-193, Portugal. Electronic address:

Advanced investigations on the use of graphene based nanomaterials have highlighted the capacity of these materials for wastewater treatment. Research on this topic revealed the efficiency of the nanocomposite synthetized by graphene oxide functionalized with polyethyleneimine (GO-PEI) to adsorb mercury (Hg) from contaminated seawater. However, information on the environmental risks associated with these approaches are still lacking. Read More

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