AAPS PharmSciTech 2021 Mar 14;22(3):104. Epub 2021 Mar 14.
Núcleo de Desenvolvimento Farmacêutico e Cosmético- NUDFAC, Departamento de Ciências Farmacêuticas, Universidade Federal de Pernambuco, Avenida Professor Artur de Sá, s/n, Cidade Universitária, Recife, Pernambuco, 50740-521, Brazil.
Pain is a phenomenon present in the majority of the population, affecting, among others, the elderly, overweight people, and especially recently operated patients, analgesia being necessary. In the specific case of relief of postoperative pain, different kinds of anesthetics are being used, among them bupivacaine, a widely used drug which promotes long-lasting analgesic effects. However, cardiotoxicity and neurotoxicity are related to its repetitive use. Read More