2,037 results match your criteria Toxicity Lithium


The 'SILENT Alarm': When History Taking Reveals a Potentially Fatal Toxicity.

Eur J Case Rep Intern Med 2018 26;5(6):000843. Epub 2018 Jun 26.

Internal Medicine 'T', Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel, affiliated to the Sackler School of Medicine, Tel-Aviv, Israel.

Introduction: The combination of acute/sub-acute neurological and metabolic derangements should always raise the suspicion of toxicity, either endogenous or exogenous. The adverse effects of psychiatric medications are especially difficult to determine since the psychiatric background of patients is often inaccessible.

Clinical Presentation: A 66-year-old man presented to the emergency department with dysarthria and uncontrolled tremor, rapidly deteriorating into a complex of severe neurological and metabolic derangements. Read More

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http://dx.doi.org/10.12890/2018_000843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346880PMC

Chemical Synthesis and Applications of Colloidal Metal Phosphide Nanocrystals.

Front Chem 2018 8;6:652. Epub 2019 Jan 8.

Beijing Key Laboratory of Construction-Tailorable Advanced Functional Materials and Green Applications, School of Materials Science & Engineering, Beijing Institute of Technology, Beijing, China.

Colloidal nanocrystals (NCs) have emerged as promising materials in optoelectronic devices and biological imaging application due to their tailorable properties through size, shape, and composition. Among these NCs, metal phosphide is an important class, in parallel with metal chalcogenide. In this review, we summarize the recent progress regarding the chemical synthesis and applications of colloidal metal phosphide NCs. Read More

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http://dx.doi.org/10.3389/fchem.2018.00652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331784PMC
January 2019
1 Read

[Renal toxicity of lithium].

Authors:
Aude Servais

Nephrol Ther 2019 Jan 15. Epub 2019 Jan 15.

Service de néphrologie adulte, hôpital Necker, université Paris Descartes, 149, rue de Sèvres, 75015 Paris, France. Electronic address:

Besides its efficiency, lithium has a narrow therapeutic index and can result in considerable toxicity. Among the potential side effects, two types of renal toxicity are observed: a decreased renal concentrating ability and a chronic renal failure. Lithium-induced polyuria is frequent, estimated to affect up to 40% of patients, and develops usually early. Read More

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http://dx.doi.org/10.1016/j.nephro.2018.11.001DOI Listing
January 2019
1 Read

Pre- and postnatal environmental boron exposure and infant growth: Results from a mother-child cohort in northern Argentina.

Environ Res 2019 Jan 7;171:60-68. Epub 2019 Jan 7.

Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden. Electronic address:

Background: Experimental studies show developmental toxicity of boron and we recently found impaired weight and length in newborns of mothers exposed to boron through drinking water during pregnancy.

Objectives: To evaluate potential impact of pre- and postnatal boron exposure on infant anthropometry.

Methods: In our mother-child cohort (n = 177) in Argentinean Andes, where drinking water concentrations of boron, lithium and arsenic have been found to vary considerably, we collected maternal blood and urine during and after pregnancy, placenta, breast milk, as well as infant urine and blood during the first 6 months of life. Read More

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http://dx.doi.org/10.1016/j.envres.2019.01.012DOI Listing
January 2019
2 Reads

The clinical characteristics and correlates of lithium toxicity in a tertiary referral centre.

Ir J Med Sci 2019 Jan 10. Epub 2019 Jan 10.

Department of Psychiatry, University Hospital Galway, Galway, Ireland.

Introduction: Lithium is a medication indicated for the treatment of bipolar disorder and treatment-resistant depression, with a narrow therapeutic index. Overdose, either acute or chronic can result in neurological symptoms, requiring dialysis and admission to intensive care in some cases. Lithium toxicity is avoidable with careful monitoring. Read More

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http://dx.doi.org/10.1007/s11845-018-01963-9DOI Listing
January 2019
1 Read

Enhanced Lithium Transport by Control of Crystal Orientation in Spinel LiMnO Thin Film Cathodes.

ACS Appl Energy Mater 2018 Dec 19;1(12):7046-7051. Epub 2018 Nov 19.

MESA+ Institute for Nanotechnology, University of Twente, 7500 AE, Enschede, Netherlands.

A promising cathode material for rechargeable batteries is LiMnO, which exhibits higher operating voltage, reduced toxicity and lower costs as compared to commonly used LiCoO cathodes. However, LiMnO suffers from limited cycle life, as excessive capacity fading occurs during battery cycling due to dissolution of Mn into the acidic electrolyte. Here, we show that by structural engineering of stable, epitaxial LiMnO thin films the electrochemical properties can be enhanced as compared to polycrystalline samples. Read More

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http://pubs.acs.org/doi/10.1021/acsaem.8b01477
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http://dx.doi.org/10.1021/acsaem.8b01477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307082PMC
December 2018
2 Reads

Lithium Salts of Krebs Cycle Substrates as Potential Normothymic Antioxidant Agents.

J Pharm Bioallied Sci 2018 Oct-Dec;10(4):240-245

Tomsk Polytechnic University, Research School Chemical and Biomedical Technologies, Department of Chemical Engineering, Tomsk, Russia.

Objective: Aim of the present work was to study the antioxidant properties of lithium salts of Krebs cycle substrates and their influence on immune cells. Lithium is a well-known and widely used mood stabilizer. These lithium-based substances have a lot of potential properties because of the anionic component of the Krebs cycle substrates, which take part in basic intracellular biochemical process. Read More

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http://dx.doi.org/10.4103/JPBS.JPBS_140_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266639PMC
December 2018
1 Read

Fluorine-free water-in-ionomer electrolytes for sustainable lithium-ion batteries.

Nat Commun 2018 12 14;9(1):5320. Epub 2018 Dec 14.

Helmholtz Institute Münster - Forschungszentrum Jülich GmbH (IEK 12), Corrensstrasse 46, 48149 Münster, D-48149, Münster, Germany.

The continuously increasing number and size of lithium-based batteries developed for large-scale applications raise serious environmental concerns. Herein, we address the issues related to electrolyte toxicity and safety by proposing a "water-in-ionomer" type of electrolyte which replaces organic solvents by water and expensive and toxic fluorinated lithium salts by a non-fluorinated, inexpensive and non-toxic superabsorbing ionomer, lithium polyacrylate. Interestingly, the electrochemical stability window of this electrolyte is extended greatly, even for high water contents. Read More

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http://dx.doi.org/10.1038/s41467-018-07331-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294254PMC
December 2018
1 Read
10.742 Impact Factor

Lithium Treatment Is Safe in Children With Intellectual Disability.

Front Mol Neurosci 2018 22;11:425. Epub 2018 Nov 22.

Henan Key Laboratory of Child Brain Injury, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Lithium is a widely used and effective treatment for individuals with psycho-neurological disorders, and it exhibits protective and regenerative properties in multiple brain injury animal models, but the clinical experience in young children is limited due to potential toxicity. As an interim analysis, this paper reports the safety/tolerability profiles of low-dose lithium treatment in children with intellectual disability (ID) and its possible beneficial effects. In a randomized, single-center clinical trial, 124 children with ID were given either oral lithium carbonate 6 mg/kg twice per day or the same dose of calcium carbonate as a placebo ( = 62/group) for 3 months. Read More

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https://www.frontiersin.org/article/10.3389/fnmol.2018.00425
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http://dx.doi.org/10.3389/fnmol.2018.00425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262083PMC
November 2018
11 Reads

Lithium Toxicity with Severe Bradycardia Post Sleeve Gastrectomy: a Case Report and Review of the Literature.

Obes Surg 2019 Feb;29(2):735-738

Bariatric Surgery Unit, General Surgery Division, The Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

Lithium is one of the major treatment options in bipolar disorder. Bariatric surgery can significantly modify the oral bioavailability of drugs, and lithium is no exception; although in most cases drug absorption seems to decrease, in the case of lithium, toxicity is the risk. In this article, we describe a 61-year-old male patient presented with lithium toxicity, including newly diagnosed severe bradycardia requiring a permanent pacemaker, after undergoing sleeve gastrectomy. Read More

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http://dx.doi.org/10.1007/s11695-018-3597-xDOI Listing
February 2019
2 Reads
3.747 Impact Factor

Delphi survey of maintenance lithium treatment in older adults with bipolar disorder: An ISBD task force report.

Bipolar Disord 2018 Oct 30. Epub 2018 Oct 30.

Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio.

Objectives: Despite the growing numbers and proportion of older adults with bipolar disorder (OABD), there are very limited guidelines for the use of lithium with its double-edged potential for effectiveness and toxicity in this population. The primary aims of this Delphi survey were: (a) To determine the place of lithium among the preferred choices for maintenance treatment of OABD. (b) To provide detailed clinical guidelines for the safe and effective use of lithium in OABD. Read More

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http://doi.wiley.com/10.1111/bdi.12714
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http://dx.doi.org/10.1111/bdi.12714DOI Listing
October 2018
17 Reads

Impacts of molybdenum-, nickel-, and lithium- oxide nanomaterials on soil activity and microbial community structure.

Sci Total Environ 2019 Feb 18;652:202-211. Epub 2018 Oct 18.

Department of Agronomy, Purdue University, West Lafayette, IN 47907, USA. Electronic address:

The nano forms of the metals molybdenum oxide (MoO), nickel oxide (NiO) and lithium oxide (LiO) are finding wide application in advanced technologies including batteries and fuel cells. We evaluated soil responses to nanoMoO, nanoNiO, and nanoLiO as some environmental release of the materials, either directly or following the land application of biosolids, is expected. Using Drummer soil (Fine-silty, mixed, superactive, mesic Typic Endoaquolls), we evaluated the impacts of the three nanometals on soil gas (NO, CH, and CO) emissions, enzyme activities (β-glucosidase and urease), and microbial community structure (bacterial, archaeal, and eukaryal) in a 60 day microcosms incubation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697183408
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http://dx.doi.org/10.1016/j.scitotenv.2018.10.189DOI Listing
February 2019
9 Reads

Lithium disturbs homeostasis of essential microelements in erythrocytes of rats: Selenium as a protective agent?

Pharmacol Rep 2018 Dec 17;70(6):1168-1172. Epub 2018 May 17.

Chair and Department of Medical Chemistry, Medical University of Lublin, Lublin, Poland.

Background: Selenium is an essential element which shows protective properties against diverse harmful factors. Lithium compounds are widely used in medicine, but, in spite of undoubted beneficial effects, treatment with these compounds may lead to severe side effects, including renal, gastrointestinal, neurological, endocrine and metabolic disorders. This study was aimed at evaluating the influence of selenium and/or lithium on lithium, iron, zinc and copper content in rats' erythrocytes as well as estimate the action of additional selenium on lithium exposure effects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17341140173079
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http://dx.doi.org/10.1016/j.pharep.2018.05.003DOI Listing
December 2018
2 Reads

Boosting Lithium-Ion Storage Capability in CuO Nanosheets via Synergistic Engineering of Defects and Pores.

Front Chem 2018 24;6:428. Epub 2018 Sep 24.

State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, China.

CuO is a promising anode material for lithium-ion batteries due to its high theoretical capacity, low cost, and non-toxicity. However, its practical application has been plagued by low conductivity and poor cyclability. Herein, we report the facile synthesis of porous defective CuO nanosheets by a simple wet-chemical route paired with controlled annealing. Read More

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https://www.frontiersin.org/article/10.3389/fchem.2018.00428
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http://dx.doi.org/10.3389/fchem.2018.00428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166579PMC
September 2018
8 Reads

C. elegans Development and Activity Test detects mammalian developmental neurotoxins.

Food Chem Toxicol 2018 Nov 25;121:583-592. Epub 2018 Sep 25.

Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, U.S.FDA, USA.

Due to the high cost and long duration of traditional testing methods for developmental neurotoxicity (DNT), only a small fraction of chemicals that humans are exposed to have been assessed for DNT activity. In order to ensure public safety, human-predictive methods for DNT detection that are faster and less resource intensive are urgently required. Using Caenorhabditis elegans, a novel worm Development and Activity test (wDAT) has been designed that uses a relatively inexpensive small-animal activity tracker and takes less than 4 days to complete. Read More

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http://dx.doi.org/10.1016/j.fct.2018.09.061DOI Listing
November 2018
2 Reads

Mechanisms of toxic cardiomyopathy.

Authors:
Philippe Hantson

Clin Toxicol (Phila) 2019 Jan 27;57(1):1-9. Epub 2018 Sep 27.

a Department of Intensive Care , Cliniques St-Luc, Université catholique de Louvain , Brussels , Belgium.

Background: Dilated cardiomyopathy is a frequent disease responsible for 40-50% of cases of heart failure. Idiopathic cardiomyopathy is a primary disorder often related to familial/genetic predisposition. Before the diagnosis of idiopathic cardiomyopathy is made, clinicians must not only rule out viral and immune causes, but also toxic causes such as drugs, environmental agents, illicit substances and natural toxins. Read More

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http://dx.doi.org/10.1080/15563650.2018.1497172DOI Listing
January 2019
10 Reads

Advances in Cathode Materials for High-Performance Lithium-Sulfur Batteries.

iScience 2018 Aug 26;6:151-198. Epub 2018 Jul 26.

Key Laboratory of Automobile Materials, Ministry of Education, College of Materials Science and Engineering, Jilin University, Changchun 130022, China. Electronic address:

Lithium-sulfur batteries (LSBs) represent a promising energy storage technology, and they show potential for next-generation high-energy systems due to their high specific capacity, abundant constitutive resources, non-toxicity, low cost, and environment friendliness. Unlike their ubiquitous lithium-ion battery counterparts, the application of LSBs is challenged by several obstacles, including short cycling life, limited sulfur loading, and severe shuttling effect of polysulfides. To make LSBs a viable technology, it is very important to design and synthesize outstanding cathode materials with novel structures and properties. Read More

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http://dx.doi.org/10.1016/j.isci.2018.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137721PMC
August 2018
4 Reads

Molecular Mechanisms of Lithium Action: Switching the Light on Multiple Targets for Dementia Using Animal Models.

Front Mol Neurosci 2018 28;11:297. Epub 2018 Aug 28.

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

Lithium has long been used for the treatment of psychiatric disorders, due to its robust beneficial effect as a mood stabilizing drug. Lithium's effectiveness for improving neurological function is therefore well-described, stimulating the investigation of its potential use in several neurodegenerative conditions including Alzheimer's (AD), Parkinson's (PD) and Huntington's (HD) diseases. A narrow therapeutic window for these effects, however, has led to concerted efforts to understand the molecular mechanisms of lithium action in the brain, in order to develop more selective treatments that harness its neuroprotective potential whilst limiting contraindications. Read More

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http://dx.doi.org/10.3389/fnmol.2018.00297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121012PMC
August 2018
4 Reads

Environmental impacts of small-scale hybrid energy systems: Coupling solar photovoltaics and lithium-ion batteries.

Sci Total Environ 2018 Dec 4;643:1579-1589. Epub 2018 Jul 4.

Sustainable Industrial Systems, School of Chemical Engineering and Analytical Science, The University of Manchester, Manchester M13 9PL, UK.

One of the benefits of hybrid solar PV-battery systems is that they can reduce grid dependency and help balance electricity supply and demand. However, their environmental impacts and benefits remain underexplored. This study considers for the first time life cycle environmental impacts of domestic-scale PV-battery systems in Turkey, integrating multi-crystalline PV and lithium-ion battery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697183236
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http://dx.doi.org/10.1016/j.scitotenv.2018.06.290DOI Listing
December 2018
9 Reads

Lithium as a disease-modifying agent for prion diseases.

Transl Psychiatry 2018 08 22;8(1):163. Epub 2018 Aug 22.

Institut de Médecine Régénératrice et de Biothérapie (I.M.R.B.), Physiopathologie, diagnostic et thérapie cellulaire des affections neurodégénératives-Institut National de la Santé et de la Recherche Médicale Université de Montpellier U1183 Centre Hospitalo, Universitaire de Montpellier, Montpellier, France.

Prion diseases still remain incurable despite multiple efforts to develop a treatment. Therefore, it is important to find strategies to at least reduce the symptoms. Lithium has been considered as a neuroprotective agent for years, and the objective of this preclinical study was to evaluate the efficacy of lithium delivered as a water-in-oil microemulsion (Aonys). Read More

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http://dx.doi.org/10.1038/s41398-018-0209-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105724PMC
August 2018
11 Reads

Search for cytotoxic compounds against ovarian cancer cells: Synthesis, characterization and assessment of the activity of new camphor carboxylate and camphor carboxamide silver complexes.

J Inorg Biochem 2018 Nov 16;188:88-95. Epub 2018 Aug 16.

Centro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10 (km 139,7), 2695-066 Bobadela LRS, Portugal.

Five silver camphor complexes of formulae [Ag(L)(L')] (1,3,5) or [Ag(L)(L')] (2,4) were synthesized from silver nitrate and the suitable camphor carboxylate (L) or camphor carboxamides (L, L). The complexes were characterized by elemental analysis and spectroscopic techniques (NMR, FTIR, XPS). Computational calculations support coordination of the carboxylate group to silver, in the case of complex 2 and combined mixed keto/carboxylate in the case of complex 1. Read More

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http://dx.doi.org/10.1016/j.jinorgbio.2018.08.011DOI Listing
November 2018
3 Reads

Toward sustainable and systematic recycling of spent rechargeable batteries.

Chem Soc Rev 2018 Oct;47(19):7239-7302

Beijing Key Laboratory of Environmental Science and Engineering, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China.

Ever-growing global energy needs and environmental damage have motivated the pursuit of sustainable energy sources and storage technologies. As attractive energy storage technologies to integrate renewable resources and electric transportation, rechargeable batteries, including lead-acid, nickel-metal hydride, nickel-cadmium, and lithium-ion batteries, are undergoing unprecedented rapid development. However, the intrinsic toxicity of rechargeable batteries arising from their use of toxic materials is potentially environmentally hazardous. Read More

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http://dx.doi.org/10.1039/c8cs00297eDOI Listing
October 2018
23 Reads
33.380 Impact Factor

Analysis of Chemical Composition of Different Irreversible Hydrocolloids.

Dent J (Basel) 2018 Aug 2;6(3). Epub 2018 Aug 2.

Faculty of Dentistry, Federal University of Rio de Janeiro, 255th Professor Rodolpho Paulo Rocco Street-Ilha do Fundão, Rio de Janeiro-RJ21941-913, Brazil.

Irreversible hydrocolloids (IR) is a dental impression material commonly used in Brazilian and European dental practice because it is inexpensive, easy to handle, has good reproductive detail and is comfortable for the patient. This research aimed to analyze the chemical composition of eight different IRs for dental use. A sample of 0. Read More

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http://dx.doi.org/10.3390/dj6030037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162557PMC
August 2018
20 Reads

Phytotoxicity of polymetallic mine wastes from southern Tuscany and Saxony.

Ecotoxicol Environ Saf 2018 Oct 14;162:505-513. Epub 2018 Jul 14.

University of Siena, Dept. of Life Sciences, University of Siena, Via Mattioli 4, I-53100 Siena, Italy.

Restoration potential of mine wastes or approaches to improve soil conditions and to ameliorate phytotoxicity on these sites may be simulated in standardized greenhouse experiments. Plants can be cultivated side by side on materials from different origins in dilution series with defined admixtures of certain aggregates. Mine wastes used in the present study originated from Fenice Capanne (FC, Tuscany, Italy) and Altenberg (ALT, Saxony, Germany). Read More

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http://dx.doi.org/10.1016/j.ecoenv.2018.07.034DOI Listing
October 2018
6 Reads

Outcomes of patient education practices to optimize the safe use of lithium: A literature review.

Ment Health Clin 2018 Jan 26;8(1):41-48. Epub 2018 Mar 26.

Clinical Pharmacist, Hamad Medical Corporation-National Center for Cancer Care and Research Hospital, Doha, Qatar.

Introduction: Lithium is commonly used to treat various psychiatric disorders and is particularly effective in the maintenance phase of bipolar disorder. Unfortunately, this drug has a narrow therapeutic index and, if not monitored regularly, can result in toxicity. Therefore, for lithium to be prescribed safely, clinicians must ensure that patients are well educated on lithium toxicity, its prevention, and symptom recognition. Read More

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http://dx.doi.org/10.9740/mhc.2018.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007520PMC
January 2018
1 Read

Lithium rechallenge after renal transplant.

Ment Health Clin 2017 Mar 23;7(2):46-50. Epub 2018 Mar 23.

Assistant Professor, The University of Texas at Austin Dell Medical School at Seton Family of Hospitals - Psychiatry Residency Program, Austin, Texas.

Mrs B is a 65-year-old, married, white woman with long-standing history of bipolar disorder type I who achieved mood stability with chronic lithium treatment. She developed end-stage renal disease, which was suspected to be the result of chronic lithium exposure in the context of medical comorbidity, and subsequently required renal transplantation. Following transplantation and discontinuation of lithium, Mrs B was unable to achieve mood stability with multiple medication trials and required more than 40 medical and psychiatric hospitalizations with eventual transition to skilled nursing care. Read More

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http://dx.doi.org/10.9740/mhc.2017.03.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007664PMC
March 2017
16 Reads

Interventions for chronic non-hypovolaemic hypotonic hyponatraemia.

Cochrane Database Syst Rev 2018 06 28;6:CD010965. Epub 2018 Jun 28.

Renal Division, Sector Metabolic and Cardiovascular Conditions, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium, 9000.

Background: Chronic (present > 48 hours) non-hypovolaemic hyponatraemia occurs frequently, can be caused by various conditions, and is associated with shorter survival and longer hospital stays. Many treatments, such as fluid restriction or vasopressin receptor antagonists can be used to improve the hyponatraemia, but whether that translates into improved patient-important outcomes is less certain.

Objectives: This review aimed to 1) look at the benefits and harms of interventions for chronic non-hypovolaemic hypotonic hyponatraemia when compared with placebo, no treatment or head-to-head; and 2) determine if benefits and harms vary in absolute or relative terms dependent on the specific compound within a drug class, on the dosage used, or the underlying disorder causing the hyponatraemia. Read More

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http://dx.doi.org/10.1002/14651858.CD010965.pub2DOI Listing
June 2018
5 Reads

Utilizing recycled LiFePO from batteries in combination with B@CN and CuFeO as sustainable nano-junctions for high performance degradation of atenolol.

Chemosphere 2018 Oct 18;209:457-469. Epub 2018 Jun 18.

College of Materials Science and Engineering, Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, Nanshan District Key Laboratory for Biopolymers and Safety Evaluation, Shenzhen University, Shenzhen, 518060, PR China. Electronic address:

In this report recycled LiFePO (LFP) from exhaust batteries was utilized to form B@CN/LiFePO/CuFeO (BLC) nano-junction as a visible active photocatalyst. The junction synthesized by two routes: Using as extracted LFP and forming LFP by extracted FePO and LiCO via in-situ deposition method. The two ternary junctions BLC and BLC (E) (utilizing as extracted LFP) were utilized for visible and solar powered degradation of beta-blocker drug Atenolol (ATL). Read More

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http://dx.doi.org/10.1016/j.chemosphere.2018.06.117DOI Listing
October 2018
4 Reads
3.340 Impact Factor

Too Hot for Your Pocket! Burns From E-Cigarette Lithium Battery Explosions: A Case Series.

J Burn Care Res 2018 Oct;39(6):1043-1047

Trauma Services, Hurley Medical Center/Michigan State University, College of Human Medicine, Flint.

The use of electronic cigarettes (ECs) has been on the rise with increased number of battery explosions causing burns. This study is a retrospective review of patients who presented with burns caused by EC explosions.Here, we present a case series of eight patients sustaining burns from EC explosions, within a year, to elucidate the pattern of such burns and to provide a treatment guideline. Read More

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http://dx.doi.org/10.1093/jbcr/irx015DOI Listing
October 2018
10 Reads

A Peapod-like CoP@C Nanostructure from Phosphorization in a Low-Temperature Molten Salt for High-Performance Lithium-Ion Batteries.

Angew Chem Int Ed Engl 2018 Aug 13;57(32):10187-10191. Epub 2018 Jul 13.

Beijing National Laboratory for Molecular Sciences (BNLMS), The State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.

A mild phosphorization process in low-temperature molten salt (NaCl-KCl-AlCl ) has been developed to synthesize peapod-like CoP@C nanostructures by using low-toxicity industrial PCl as the phosphorus source and Mg as the reductant at 250 °C. Importantly, high efficiency of the phosphorous source is achieved since only stoichiometric PCl is required to complete the reaction. The molten NaCl-KCl-AlCl not only provides a liquid environment but also participates in the electron transport by the reversible conversion of the Al /Al redox couple. Read More

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http://dx.doi.org/10.1002/anie.201805468DOI Listing
August 2018
59 Reads

Toxic-induced cerebellar syndrome: from the fetal period to the elderly.

Handb Clin Neurol 2018 ;155:333-352

Neurology Service, Hôpital Erasme, Brussels, Belgium.

The cerebellum is a brain region which is particularly susceptible to intoxication. Clinical presentation is heterogeneous. It is often considered that elderly patients and patients presenting pre-existing structural lesions of the posterior fossa are particularly at risk of developing a toxic-induced cerebellar syndrome (TOICS). Read More

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http://dx.doi.org/10.1016/B978-0-444-64189-2.00022-6DOI Listing
October 2018
16 Reads

Highly-stable Li ion-selective electrodes based on noble metal nanostructured layers as solid-contacts.

Anal Chim Acta 2018 Oct 11;1027:22-32. Epub 2018 May 11.

Laboratory of Integrated System, EPFL, CH-1015, Lausanne, Switzerland.

Nowadays the development of stable and highly efficient Solid-Contact Ion-Selective Electrodes (SC-ISEs) attracts much attention in the research community because of the great expansion of portable analytical devices. In this work, we present highly stable Li all-solid-state ISEs exploiting noble metals nanostructures as ion-to-electron transducers. The detection of lithium is essential for therapeutic drug monitoring of bipolar patients. Read More

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http://dx.doi.org/10.1016/j.aca.2018.04.062DOI Listing
October 2018
3 Reads

Lithium entrapped chitosan nanoparticles to reduce toxicity and increase cellular uptake of lithium.

Environ Toxicol Pharmacol 2018 Jul 24;61:79-86. Epub 2018 May 24.

Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, Tamil Nadu, 603103, India. Electronic address:

Lithium carbonate is an effective drug against bipolar disorders. Direct use of lithium carbonate has been reported to result in lithium toxication and pulmonary complications. With chitosan micro and nanoparticles gaining attention for their protein absorption, drug targeting and improved dissolution rate of sparingly water-soluble drugs, this work has focused on chitosan loaded Li as a possible alternative to Li alone for cellular uptake. Read More

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http://dx.doi.org/10.1016/j.etap.2018.05.017DOI Listing
July 2018
2 Reads

Comparison of solvate ionic liquids and DMSO as an in vivo delivery and storage media for small molecular therapeutics.

BMC Biotechnol 2018 05 29;18(1):32. Epub 2018 May 29.

Metabolic Genetic Diseases Laboratory, Metabolic Research Unit, Deakin University School of Medicine, 75 Pigdons Road, Geelong, VIC, 3216, Australia.

Background: Solvate ionic liquids (SILs) are a new class of ionic liquids that are equimolar solutions of lithium bistrifluoromethanesulfonimide in either triglyme or tetraglyme, referred to as G3LiTFSA and G4LiTFSA, respectively. SILs play a role in energy storage lithium batteries, and have been proposed as potential alternatives to traditional organic solvents such as DMSO. G3TFSA and G4TFSA have been shown to exhibit no toxicity in vivo up to 0. Read More

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https://bmcbiotechnol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12896-018-0442-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975478PMC
May 2018
8 Reads

Response to metals treatment of Fra1, a member of the AP-1 transcription factor family, in P. lividus sea urchin embryos.

Mar Environ Res 2018 Aug 5;139:99-112. Epub 2018 May 5.

Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare "A. Monroy", Via Ugo La Malfa 153, 90146, Palermo, Italy. Electronic address:

Lithium (Li), Nickel (Ni), and Zinc (Zn) are metals normally present in the seawater, although they can have adverse effects on the marine ecosystem at high concentrations by interfering with many biological processes. These metals are toxic for sea urchin embryos, affecting their morphology and developmental pathways. In particular, they perturb differently the correct organization of the embryonic axes (animal-vegetal, dorso-ventral): Li is a vegetalizing agent and Ni disrupts the dorso-ventral axis, while Zn has an animalizing effect. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01411136173070
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http://dx.doi.org/10.1016/j.marenvres.2018.05.003DOI Listing
August 2018
7 Reads

First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties.

Curr Top Med Chem 2018 ;18(5):418-427

Department of Biomedical Sciences, University of Leon, Campus de Vegazana, 24071, Leon, Spain.

Introduction: The first total synthesis of ω-phenyl Δ6 fatty acids (FA) and their cytotoxicity (A549) and leishmanicidal (L. infantum) activities are described. The novel 16-phenyl-6-hexadecynoic acid (1) and the known 16-phenylhexadecanoic acid (2) were synthesized in 7-8 steps with overall yields of 46 % and 41 %, respectively. Read More

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http://www.eurekaselect.com/162207/article
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http://dx.doi.org/10.2174/1568026618666180516125056DOI Listing
July 2018
19 Reads

Policosanol fabrication from insect wax and optimization by response surface methodology.

PLoS One 2018 15;13(5):e0197343. Epub 2018 May 15.

Research Institute of Resources Insects, Chinese Academy of Forestry, Kunming, Yunnan, China.

Background: Insect wax is a famous biological resource for the role in economic production in China. Insect wax is a good source of policosanol, which may is a candidate supplement in foodstuff and pharmaceuticals that has important physiological activities. Therefore, this work aims to investigate a high-yield and rapid method for policosanol fabrication from insect wax. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197343PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953464PMC
November 2018
4 Reads

Glyoxal-Based Solvents for Electrochemical Energy-Storage Devices.

ChemSusChem 2018 Jun 25;11(12):1919-1926. Epub 2018 May 25.

Institute for Technical Chemistry and Environmental Chemistry, Friedrich-Schiller-University Jena, Philosophenweg 7a, 07743, Jena, Germany.

In this work an investigation about the use of the solvents 1,1,2,2-tetramethoxyethane, also called tetramethoxy glyoxal (TMG), and 1,1,2,2-tetraethoxyethane [also called tetraethoxy glyoxal (TEG)], which belong to the chemical family of carbonyl derivatives, as electrolyte components for electrical double layer capacitors (EDLCs) and lithium-ion batteries (LIBs) is reported for the first time. TEG and TMG are commercial solvents displaying a good set of properties, a low toxicity, and a low price. Although for EDLCs the use of these solvents does appear particularly appealing, their use in LIBs is certainly interesting. Read More

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http://dx.doi.org/10.1002/cssc.201800375DOI Listing
June 2018
1 Read

Electroencephalography in the monitoring of lithium toxicity: A case report.

Authors:
T Omi

J Clin Pharm Ther 2018 Aug 2;43(4):584-586. Epub 2018 May 2.

Department of Psychiatry, Osaka General Medical Center, Osaka, Japan.

What Is Known And Objective: If lithium toxicity occurs during treatment by lithium, treatment is performed while monitoring serum lithium levels.

Case Summary: We report a case of lithium toxicity in a patient with bipolar affective disorder who developed neurotoxic symptoms associated with elevated serum lithium level and abnormal electroencephalography (EEG) changes. The elevated serum lithium level decreased before EEG normalization, which was associated with disappearance of all neurotoxic symptoms. Read More

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http://dx.doi.org/10.1111/jcpt.12685DOI Listing
August 2018
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Interplay between elemental imbalance-related PI3K/Akt/mTOR-regulated apoptosis and autophagy in arsenic (III)-induced jejunum toxicity of chicken.

Environ Sci Pollut Res Int 2018 Jul 28;25(19):18662-18672. Epub 2018 Apr 28.

Department of Physiology, College of Wildlife Resources, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.

Arsenic trioxide (AsO), the most toxic form of arsenic found in foodstuffs, is considered a carcinogen for human and animal. But many of the events that occur during its passage through the gastrointestinal tract are uncharted in birds. This study assesses the toxic effect on the jejunum of chicken which subchronically exposed to diets that contain AsO (0, 0. Read More

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http://dx.doi.org/10.1007/s11356-018-2059-2DOI Listing
July 2018
7 Reads

Dissolution Mechanisms of LiNiMnCoO Positive Electrode Material from Lithium-Ion Batteries in Acid Solution.

ACS Appl Mater Interfaces 2018 May 4;10(19):16424-16435. Epub 2018 May 4.

Institut de Chimie Séparative de Marcoule (ICSM), UMR 5257 CEA-CNRS-UM-ENSCM, Centre de Marcoule , BP 17171, 30207 Bagnols-sur-Cèze Cedex , France.

The sustainability through the energy and environmental costs involve the development of new cathode materials, considering the material abundance, the toxicity, and the end of life. Currently, some synthesis methods of new cathode materials and a large majority of recycling processes are based on the use of acidic solutions. This study addresses the mechanistic and limiting aspects on the dissolution of the layered LiNiMnCoO oxide in acidic solution. Read More

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http://dx.doi.org/10.1021/acsami.8b01352DOI Listing
May 2018
6 Reads

Highly reversible zinc metal anode for aqueous batteries.

Nat Mater 2018 Jun 16;17(6):543-549. Epub 2018 Apr 16.

Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD, USA.

Metallic zinc (Zn) has been regarded as an ideal anode material for aqueous batteries because of its high theoretical capacity (820 mA h g), low potential (-0.762 V versus the standard hydrogen electrode), high abundance, low toxicity and intrinsic safety. However, aqueous Zn chemistry persistently suffers from irreversibility issues, as exemplified by its low coulombic efficiency (CE) and dendrite growth during plating/ stripping, and sustained water consumption. Read More

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http://dx.doi.org/10.1038/s41563-018-0063-zDOI Listing
June 2018
5 Reads

Impact of the Di(2-Ethylhexyl) Phthalate Administration on Trace Element and Mineral Levels in Relation of Kidney and Liver Damage in Rats.

Biol Trace Elem Res 2018 Dec 13;186(2):474-488. Epub 2018 Apr 13.

School of Medicine, Department of Medical Biochemistry, Koc University, Rumelifeneri Yolu, Sariyer, 34450, Istanbul, Turkey.

Di(2-ethylhexyl) phthalate (DEHP) is a widely used synthetic polymer in the industry. DEHP may induce reproductive and developmental toxicity, obesity, carcinogenesis and cause abnormal endocrine function in both human and wildlife. The aim of this study was to investigate trace element and mineral levels in relation of kidney and liver damage in DEHP-administered rats. Read More

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http://dx.doi.org/10.1007/s12011-018-1331-0DOI Listing
December 2018
9 Reads