Arch Oral Biol 2021 May 24;125:105093. Epub 2021 Feb 24.
Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, 710004 Shaanxi, China; Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xi'an Jiaotong University, 710004 Shaanxi, China; Department of Preventive Dentistry, College of Stomatology, Xi'an Jiaotong University, Xi'an, China. Electronic address:
Objectives: The present study aimed to investigated the effect and mechanism of Ca treatment on fluoride in ameloblast-lineage cells (ALCs).
Materials And Methods: The effects of fluoride and different Ca levels treatment on the proliferative activity, cell apoptosis, cell cycle, intracellular free Ca, were firstly determined. Kallikrein 4 (KLK4), glucose-responsive protein 78 (GRP78), Protein kinase R -like endoplasmic reticulum kinase (PERK), the α subunit of eukaryotic initiation factor 2 (eIF2α), activating transcription factor 4 (ATF4), CCAAT enhancer-binding protein homologous protein (CHOP), were investigated in ALCs. Read More