Search Our Scientific Publications & Authors

Appl Microbiol Biotechnol 2023 Sep 22. Epub 2023 Sep 22.

Biotechnology Group, Chemical Engineering Department, Tarbiat Modares University, Tehran, Iran.

In the context of e-waste recycling by fungal bioleaching, nickel and cobalt precipitate as toxic metals by oxalic acid, whereas organic acids, such as citric, act as a high-performance chelating agent in dissolving these metals. Oxalic acid elimination requires an excess and uneconomical carbon source concentration in culture media. To resolve this issue, a novel and straightforward systems metabolic engineering method was devised to switch metabolic flux from oxalic acid to citric acid. Read More

Biol Trace Elem Res 2023 Sep 20. Epub 2023 Sep 20.

College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, China.

Fluoride, a global environmental pollutant, is ubiquitous in aquatic environments and coexists with selenium, which can cause complex effects on exposed organisms. However, data on the interaction of fluoride and selenium remain scarce. In this study, female zebrafish (Danio rerio) were exposed to fluoride (80 mg/L sodium fluoride) and/or dietary selenomethionine for 30, 60 and 90 days, the effects on the liver of zebrafish were investigated. Read More

Sci Total Environ 2023 Sep 17;905:167103. Epub 2023 Sep 17.

Department of Geochemistry, Petrology and Geological Prospecting, University of Barcelona, Barcelona, Spain.

This study assesses the potential impacts on human health of volcanic ash emitted during the 2021 Tajogaite eruption (La Palma Island, Spain). Ash samples were physically and chemically characterized and leaching tests (with deionized water and acidic solution) were performed according to the IVHHN protocols to elucidate i) the leachable elements that may affect water quality and represent a potential threat for livestock and humans through drinking water supply; and ii) the bioaccessible fraction of toxicants able to be solubilized from ash surfaces if ashes are incidentally ingested by children. The most abundant readily water-soluble compounds were SO, F, Cl, Na, Ca, Ba, Mg, and Zn. Read More

Environ Geochem Health 2023 Sep 16. Epub 2023 Sep 16.

Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, 150081, Heilongjiang Province, China.

Previous studies indicate that fluoride in drinking water has a toxic effect on cartilage and skeleton, which triggers osteoarthritis (OA) of which the most frequent is knee OA (KOA). A cross-sectional study was conducted to assess the association between fluoride exposure and KOA among 1128 subjects. Water fluoride (WF) and urinary fluoride (UF) were chosen as external exposure (internal exposure) of fluoride. Read More

Front Public Health 2023 30;11:1247294. Epub 2023 Aug 30.

Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.

Introduction: Fluoride is considered an environmental pollutant that seriously affects organisms and ecosystems, and its harmfulness is a perpetual public health concern. The toxic effects of fluoride include organelle damage, oxidative stress, cell cycle destruction, inflammatory factor secretion, apoptosis induction, and synaptic nerve transmission destruction. To reveal the mechanism of fluorosis-induced brain damage, we analyzed the molecular mechanism and learning and memory function of the SIRT1-mediated BDNF-TrkB signaling pathway cascade reaction in fluorosis-induced brain damage through experiments. Read More

ACS Appl Polym Mater 2023 Sep 3;5(9):7144-7154. Epub 2023 Aug 3.

Center of Physics, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.

Flexible and conformable conductive composites have been developed using different polymers, including water-based polyvinylpyrrolidone (PVP), chemical-resistant polyvinylidene fluoride (PVDF), and elastomeric styrene-ethylene-butylene-styrene (SEBS) reinforced with nitrogen-doped reduced graphene oxide with suitable viscosity in composites for printable solutions with functional properties. Manufactured by screen-printing using low-toxicity solvents, leading to more environmentally friendly conductive materials, the materials present an enormous step toward functional devices. The materials were enhanced in terms of filler/binder ratio, achieving screen-printed films with a sheet resistance lower than < 100 Ω/sq. Read More

J Hazard Mater 2023 Oct 1;460:132445. Epub 2023 Sep 1.

School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address:

To overcome the drawbacks of current recycling technologies and achieve clean utilization of toxic substances in spent lithium-ion batteries, a lithium synergistic vacuum catalytic co-pyrolysis method was proposed to defluorinate electrolyte and polyvinylidene fluoride with directional conversion to light fuel. The gas chromatography-mass spectrometry results indicated, compared to the control group, that adding CaO-ZSM-5 catalyst increased the light fuel (alcohols and hydrocarbons) content of the pyrolysis gas from 61.8 % to 91. Read More

Chem Commun (Camb) 2023 Sep 13. Epub 2023 Sep 13.

Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, China.

Compared with commercial bulk scintillators and halide perovskites, lanthanide-doped fluoride nanoscintillators (NSs) exhibit high photochemical stability, low bio-toxicity and tunable emissions. However, the widely employed hosts, such as NaGdF, NaLuF and NaYF, need many expensive rare earth salts and time-consuming reaction processes. In this work, lanthanide-doped NaBiF NSs were prepared by a facile rapid room-temperature reaction method. Read More

ACS Nano 2023 Sep 13. Epub 2023 Sep 13.

Biology Program, Division of Science, New York University Abu Dhabi, P.O. Box 129188, Saadiyat Island, Abu Dhabi, United Arab Emirates.

Photodynamic therapy (PDT) and photothermal therapy (PTT) have gained considerable attention as potential alternatives to conventional cancer treatments. However, these approaches remain limited by low solubility, poor stability, and inefficient targeting of many common photosensitizers (PSs) and photothermal agents (PTAs). To overcome the aforementioned limitations, we engineered biocompatible and biodegradable tumor-targeted upconversion nanospheres with imaging capabilities. Read More

Sci Total Environ 2023 Sep 9;903:166961. Epub 2023 Sep 9.

College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Department of Chemistry, Clemson University, Clemson 29634, SC, United States. Electronic address:

In natural waters, hydroxyl radical (OH) can initiate many free radical-induced reactions, oxidizing various inorganic and organic compounds through electron transfer reactions, dehydrogenation reactions, addition reactions, and self-quenching reactions. However, due to its extremely low concentration and short lifetime in natural waters, studies on the quantitative measurement of OH levels are insufficient. In this work, we developed the first quinolinium-based fluorescence probe containing fluoride substituted donor that could detect hydroxyl radicals in the water system. Read More

Environ Toxicol 2023 Sep 11. Epub 2023 Sep 11.

National & Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Due to the high abundance in the Earth's crust and industrial application, fluoride is widely present in our living environment. However, excessive fluoride exposure causes toxicity in different organs. As the most important detoxification and excretion organ, liver is more easily involved in fluoride toxicity than other organs, and oxidative stress is considered as the key mechanism related with fluoride hepatotoxicity. Read More

Biol Trace Elem Res 2023 Sep 8. Epub 2023 Sep 8.

College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, China.

Fluoride, a global environmental pollutant, is ubiquitous in aquatic environments and coexists with selenium, which can cause complex effects on exposed organisms. However, data on the interaction of fluoride and selenium remain scarce. In this study, female zebrafish (Danio rerio) were exposed to fluoride (80 mg/L sodium fluoride) and/or dietary selenomethionine (Se-Met) for 30, 60 and 90 days, the effects on the liver of zebrafish were investigated. Read More

J Hazard Mater 2023 Oct 30;460:132443. Epub 2023 Aug 30.

Department of Botany, GDC, Pulwama 192301, Jammu and Kashmir, India.

Fluoride (F), and arsenic (As) in the groundwater cause health problems in developing countries, including Pakistan. We evaluated the occurrence, distribution, sources apportionment, and health hazards of F, and As in the groundwater of Mardan, Pakistan. Therefore, groundwater samples (n = 130) were collected and then analyzed for F, and As by ion-chromatography (IC) and Inductively-coupled plasma mass-spectrometry (ICP-MS). Read More

ACS Appl Energy Mater 2023 Aug 14;6(16):8616-8625. Epub 2023 Aug 14.

POLYMAT, University of the Basque Country UPV/EHU, Avenida Tolosa 72, Donostia-San Sebastián 20018, Spain.

Poly(vinylidene fluoride) (PVDF) is the most common binder for cathode electrodes in lithium-ion batteries. However, PVDF is a fluorinated compound and requires toxic -methyl-2-pyrrolidone (NMP) as a solvent during the slurry preparation, making the electrode fabrication process environmentally unfriendly. In this study, we propose the use of carrageenan biopolymers as a sustainable source of water-processable binders for high-voltage NMC811 cathodes. Read More

Chemistry 2023 Aug 29:e202302544. Epub 2023 Aug 29.

Chemnitz University of Technology: Technische Universitat Chemnitz, Institut für Chemie, Straße der Nationen 62, 09111, Chemnitz, GERMANY.

The dinuclear bis(N-heterocyclic carbene) borane adduct 2 rapidly reacts with tritylium salts at room temperature but the outcome is strongly impacted by the respective counter-ion. Using tritylium tetrakis(perfluoro-tert-butoxy)aluminate affords - depending on the solvent - either the bis(boronium) ion 4 or the hydride-bridged dication 5. In case of tritylium hexafluorophosphate, however, H/F exchange occurs between boron and phosphorus yielding the dinuclear BF3 adduct 3 along with phosphorus dihydride trifluoride. Read More

Molecules 2023 Aug 15;28(16). Epub 2023 Aug 15.

Department of Medical Chemistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.

The exposure of humans to fluorine is connected with its presence in the air, food and water. It is well known that fluorides even at a low concentration but with long time exposure accumulate in the body and lead to numerous metabolic disorders. Fluoride is recognised as a factor modulating the energy metabolism of cells. Read More

Commun Chem 2023 Aug 24;6(1):178. Epub 2023 Aug 24.

Communications Chemistry, .

Fluorochemicals have a wide range of applications in industry, but accessing these relies on the energy intensive conversion of acid-grade fluorspar (CaF) to toxic hydrogen fluoride (HF) gas, which is in turn used for the downstream production of fluorochemicals via multistep processes. Now, directly treating acid-grade fluorspar with dipotassium hydrogen phosphate (KHPO) under mechanochemical conditions affords a fluorinating reagent for direct S–F and C(sp/sp)–F bond construction, bypassing the need for HF production. Read More

Environ Sci Pollut Res Int 2023 Aug 23. Epub 2023 Aug 23.

Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, India.

Fluoride (F) contamination in drinking water is a major global concern. According to several studies, India and China are the most affected by the presence of excess F. Long-time exposure to F concentrations above 1. Read More

Environ Sci Pollut Res Int 2023 Aug 23. Epub 2023 Aug 23.

School of Civil and Environmental Engineering, IIT Mandi, Himachal Pradesh, Mandi, 175005, India.

The state known as the bread basket of India has now been defamed as the cancer capital of the country. The toxicity of groundwater associated with the declining water level is reported in recent years. However, an extensive temporal and spatial analysis is required to identify hotspots. Read More

Environ Geochem Health 2023 Aug 23. Epub 2023 Aug 23.

Institute of Geographic Sciences and Natural Resources Research, CAS, Beijing, 100101, China.

The massive exploration and random dumping of coals in various regions of China create serious environmental and health problems because of the presence of toxic trace elements (TTEs), which possibly transfer to environment and cause serious health issues. This study was conducted to probe the environmental consequences of coalmines on the aquifer water and their association with health risks and the environment. For this purpose, 100 s of water samples was collected from the typical coalmine regions of Hancheng, Huanglong, Binxian, Handan, Langao, and Fusui and analyzed for various parameters. Read More

Environ Res 2023 Aug 12;237(Pt 1):116879. Epub 2023 Aug 12.

Faculty of Chemical and Materials Engineering, Shahrood University of Technology, Shahrood, Iran. Electronic address:

The main obstacles in adopting solvent-based CO capture technology from power plant flue gases at the industrial scale are the energy requirements for solvent regeneration and their toxicity. These challenges can be overcome using new green and more stable ionic liquids (ILs) as solvents for post-combustion CO capture. In the current study, tributyl-tetradecyl-phosphonium chloride [P][Cl] as an IL, was immobilized on hydrophobic porous supports of polypropylene (PP), polyvinylidene fluoride (PVDF), and polytetrafluoroethylene (PTFE) at 298 ± 3 K and pressures up to 2 bar. Read More

Int J Clin Oncol 2023 Aug 12. Epub 2023 Aug 12.

Department of Nephrology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

This comprehensive review discusses the dosing strategies of cancer treatment drugs for patients with impaired kidney function, specifically those with chronic kidney disease (CKD), undergoing hemodialysis, and kidney transplant recipients. CKD patients often necessitate dose adjustments of chemotherapeutic agents, e.g. Read More

Materials (Basel) 2023 Jul 25;16(15). Epub 2023 Jul 25.

Department of Epidemiology and Public Health, Tokyo Dental College, Tokyo 101-0061, Japan.

Sodium monofluorophosphate (NaFPO, MFP) is mainly used as an ingredient in fluoride-based dentifrices as it has a high safety profile, with one-third of the toxicity of sodium fluoride (NaF), as well as the ability to reach deep into the dentin. The purpose of this study was to assess the prevention of dentin erosion by MFP upon exposure to citric acid, which has a chelating effect, and to compare the effects to those of the conventional acidulated phosphate fluoride (APF) application method. Bovine dentin was used, and four groups were created: (i) APF (9000 ppmF, pH 3. Read More

Clin Nucl Med 2023 Oct 3;48(10):e487-e488. Epub 2023 Aug 3.

From the Naval Medical Center Portsmouth, Portsmouth, VA.

Skeletal fluorosis is more common in the developing world, but is occasionally seen in the United States. We present radiographic, scintigraphic, CT, and clinical images of a 26-year-old woman with rapidly progressive, debilitating, polyostotic periostitis, and diffuse osteosclerosis typical of skeletal fluorosis. Laboratory analyses supported this diagnosis. Read More

Environ Res 2023 Aug 7;236(Pt 2):116845. Epub 2023 Aug 7.

Department of Zoology, Visva-Bharati, Santiniketan, 731235, West Bengal, India. Electronic address:

Globally, 200 million people are suffering from toxic manifestations of Fluoride(F), dental and skeletal fluorosis; unfortunately, there is no treatment. To unravel the pathogenesis of skeletal fluorosis, we established fluorosis mice by treating environmentally relevant concentration of F (15 ppm NaF) through drinking water for 4 months. As in skeletal fluorosis, locomotor disability, crippling deformities occur and thus, our hypothesis was F might adversely affects collagen which gives the bone tensile strength. Read More

Angew Chem Int Ed Engl 2023 Sep 21;62(39):e202307054. Epub 2023 Aug 21.

Department of Dermatology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, 610041, Chengdu, P. R. China.

Aryl fluorides are important structural motifs in many pharmaceuticals. Although the Balz-Schiemann reaction provides an entry to aryl fluorides from aryldiazonium tetrafluoroborates, it suffers from drawbacks such as long reaction time, high temperature, toxic solvent, toxic gas release, and low functional group tolerance. Here, we describe a general method for the synthesis of aryl fluorides from aryldiazonium tetrafluoroborates using a piezoelectric material as redox catalyst under ball milling conditions in the presence of Selectfluor. Read More

Int J Clin Pediatr Dent 2023 ;16(2):244-250

Department of Pediatric and Preventive Dentistry, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India.

Aim: To evaluate the remineralizing potential of natural substances on artificially induced caries lesions in primary teeth.

Materials And Methods: A total of 50 primary molar teeth were selected and subjected to a demineralization process. Then samples were randomly divided into five groups for the remineralization process. Read More

Toxics 2023 Jul 5;11(7). Epub 2023 Jul 5.

The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550025, China.

The phosphorus chemical plant (PCP) production process leads to the substantial discharge of fluoride into the surrounding environment. However, there is limited research data regarding the pollution levels and ecological safety thresholds of farmland fluoride around PCPs in karst areas. This study evaluates the local contamination status and health risks by determining the fluoride content in farmland and vegetables in vicinity of a PCP in a karst area of Southwestern China. Read More

Toxics 2023 Jul 2;11(7). Epub 2023 Jul 2.

Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

The present study was conducted to evaluate the quality of drinking water and assess the potential health hazards due to water contaminants in selected urban areas of Lahore, Pakistan. Water samples were collected from ten sites and analyzed for different physico-chemical parameters including turbidity, color, pH, total dissolved solids (TDS), nitrates, fluoride, residual chlorine, and total hardness. Additionally, heavy metal (arsenic) and microbial parameters () were also determined in the water samples. Read More