Mutat Res Genet Toxicol Environ Mutagen 2022 Jun 31;878:503484. Epub 2022 Mar 31.
Laboratory of Genetic Toxicology, PPGBioSaúde (Postgraduate Program in Cellular and Molecular Biology Applied to Health), Lutheran University of Brazil (ULBRA), Av. Farroupilha, 8001, Building 22 (4th floor), 92425-900, Canoas, RS, Brazil; Laboratory of Genetic Toxicology, PPGSDH, La Salle University (UniLaSalle), Av. Victor Barreto, 2288, 92010-000, Canoas, RS, Brazil. Electronic address:
Pollution of aquatic ecosystems is associated with the discharge of mainly industrial and urban effluents, which may cause damage to public health. This study aims to evaluate the cytotoxic, genotoxic, and mutagenic potential of surface water samples under the influence of different anthropogenic effluents in a human-derived liver cell line (HepG2). Samples were collected in Esteio and Sapucaia streams (Rio Grande do Sul; Brazil), which flow into the Sinos River, a source of water supply for more than one million people. Read More