Pharmaceuticals (Basel) 2022 May 11;15(5). Epub 2022 May 11.
Food and Nutrition Academic and Research Cluster, Institute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Alzheimer's disease (AD) is a progressive neurological illness with few effective treatments. Thus, ameliorating the effects of AD using natural products has attracted global attention with promising efficacy and safety. In this study, ten tropical fruits including 'Phulae', 'Pattavia', 'Khaekdum', 'Khaeknuan', 'Monthong', 'Chanee', 'Kimju', 'Keenok', 'Kaew' and 'Namdokmai' were screened for their inhibitory activities against the key enzymes, cholinesterases and β-secretase (BACE-1), involved in AD pathogenesis. Read More