9,724 results match your criteria Toxicity Arsenic


Dimethylmonothioarsenate Is Highly Toxic for Plants and Readily Translocated to Shoots.

Environ Sci Technol 2022 Jun 27. Epub 2022 Jun 27.

Plant Physiology, Bayreuth Center for Ecology and Environmental Research (BayCEER), University of Bayreuth, D-95440 Bayreuth, Germany.

Arsenic is one of the most relevant environmental pollutants and human health threats. Several arsenic species occur in soil pore waters. Recently, it was discovered that these include inorganic and organic thioarsenates. Read More

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Heavy metal(loid)s contaminations in soils of Pakistan: a review for the evaluation of human and ecological risks assessment and spatial distribution.

Environ Geochem Health 2022 Jun 27. Epub 2022 Jun 27.

Institute of Chemical Sciences, University of Peshawar, Peshawar, Pakistan.

Heavy metal(loid)s (HM) contaminations in the soil poses threats to the human and ecological community due to their bioaccumulation, toxicity, and persistent nature in the ecosystem. This review was designed to know about the HM contamination in soils, ecological risk, distribution, and potential health risks. Soil HM concentrations published in the last 30 years were collected from Springer, Science Direct, Willey, Mendeley, ResearchGate, Google Scholar, etc. Read More

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Ecotoxicological assessment of complex environmental matrices from the lower Paraná River basin.

Chemosphere 2022 Jun 23:135385. Epub 2022 Jun 23.

Instituto de Investigación e Ingeniería Ambiental, IIIA, CONICET-UNSAM, 3iA, Campus Miguelete, 25 de Mayo y Francia, C.P. 1650, San Martín, Provincia de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina. Electronic address:

Sediments of aquatic ecosystems constitute the fate of most atmospheric and terrestrial pollutants. Since aquatic organisms, such as amphibians, interact with sediments, the presence of pollutants may affect their survival, growth and reproduction. So, the aim of this study was to evaluate, the sediment and water quality of five sites from the lower basin of the Paraná River (Buenos Aires, Argentina) with different anthropic impacts: Morejón stream (S1), de la Cruz stream upstream (S2) and downstream (S3), Arrecifes river (S4), tributary stream of Arrecifes river (S5). Read More

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Use of Generalized Weighted Quantile Sum Regressions of Tumor Necrosis Factor Alpha and Kidney Function to Explore Joint Effects of Multiple Metals in Blood.

Int J Environ Res Public Health 2022 Jun 16;19(12). Epub 2022 Jun 16.

Graduate Institute of Medicine, College of Medicine, Kaohsiung Medicine University, Kaohsiung City 807, Taiwan.

Exposure to heavy metals could lead to adverse health effects by oxidative reactions or inflammation. Some essential elements are known as reactors of anti-inflammatory enzymes or coenzymes. The relationship between tumor necrosis factor alpha (TNF-α) and heavy metal exposures was reported. Read More

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Reducing conditions increased the mobilisation and hazardous effects of arsenic in a highly contaminated gold mine spoil.

J Hazard Mater 2022 Aug 27;436:129238. Epub 2022 May 27.

University of Wuppertal, School of Architecture and Civil Engineering, Institute of Foundation Engineering, Water, and Waste-Management, Laboratory of Soil, and Groundwater-Management, Pauluskirchstraße 7, 42285 Wuppertal, Germany. Electronic address:

Arsenic (As) redox-induced mobilisation and speciation in polluted gold mine sites in tropical climates largely remains unknown. Here, we investigated the impact of changes in soil redox potential (E) (-54 mV to +429 mV) on mobilisation of As and its dominant species in an abandoned spoil (total As = 4283 mg/kg) using an automated biogeochemical microcosm set-up. Arsenic mobilisation increased (85-137 mg/L) at moderately reducing conditions (-54 mV to + 200 mV)), while its reduced (6-35 mg/L) under oxic conditions (+200 to +400 mV). Read More

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DNA hydroxymethylation reprogramming of β-oxidation genes mediates early-life arsenic-evoked hepatic lipid accumulation in adult mice.

J Hazard Mater 2022 05 18;430:128511. Epub 2022 Feb 18.

Department of Toxicology, Anhui Medical University, Hefei 230032, China. Electronic address:

The metabolic disorders are becoming an epidemic disease endangering public health in countries. Environmental factors are mainly reason for the growth of metabolic disorders. Previous research suggests that DNA methylation is a potential mechanism. Read More

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An experimental comparison: Horizontal evaluation of valuable metal extraction and arsenic emission characteristics of tailings from different copper smelting slag recovery processes.

J Hazard Mater 2022 05 16;430:128493. Epub 2022 Feb 16.

Beijing Key Laboratory for special melting and preparation of high-end metal materials, Beijing 100083, China; University of Science and Technology Beijing, School of Automation and Electrical Engineering, Beijing 100083, China.

This study comprehensively investigated arsenic's enrichment, distribution, and characteristics in tailings. XRD and SEM-EDS characterized the phase and morphology of tailings from various smelting processes. At the same time, the embedding characteristics of arsenic in the ore phase were analyzed by EPMA. Read More

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Curcumin Alleviates Arsenic Trioxide-Induced Inflammation and Pyroptosis via the NF-κB/NLRP3 Signaling Pathway in the Hypothalamus of Ducks.

Biol Trace Elem Res 2022 Jun 23. Epub 2022 Jun 23.

College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.

Arsenic (As) as a neurotoxic environmental pollutant has attracted extensive attention. Curcumin (Cur) is a natural antioxidant that shows an excellent protective effect against arsenic trioxide (ATO)-induced toxicity in many animal organs. However, the mechanism of Cur against ATO-induced hypothalamic toxicity in ducks has not yet been fully elucidated. Read More

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Evaluating the Potential Health Risks of Selected Heavy Metals across Four Wastewater Treatment Water Works in Durban, South Africa.

Toxics 2022 Jun 20;10(6). Epub 2022 Jun 20.

Environmental Pollution and Remediation Research Group, Department of Chemical Engineering, Mangosuthu University of Technology, Durban 4031, South Africa.

Poor and inadequate sanitation systems have been considered not only a human health issue, but also an environmental threat that instigates climate change. Nine heavy metals-arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), iron (Fe), manganese (Mn), nickel (Ni), lead (Pb), and zinc (Zn)-were evaluated in influent and effluent water samples from four wastewater treatment plants in the Durban metropolis, KwaZulu-Natal, South Africa. The results indicate that the mean concentrations of all the heavy metals in the influent samples ranged from 0. Read More

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Ferroptosis as a mechanism of non-ferrous metal toxicity.

Arch Toxicol 2022 Jun 21. Epub 2022 Jun 21.

Laboratory of Molecular Dietetics, IM Sechenov First Moscow State Medical University (Sechenov University), 119435, Moscow, Russia.

Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron metabolism and induction of oxidative stress and lipid peroxidation, ferroptosis might be involved in such toxicity. Although direct evidence is insufficient, certain pioneering studies have demonstrated a crosstalk between metal toxicity and ferroptosis. Read More

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Hepatorenal Toxicity of Inorganic Arsenic in White Pekin Ducks and Its Amelioration by Using Ginger.

Biol Trace Elem Res 2022 Jun 20. Epub 2022 Jun 20.

Department of Plant Breeding and Genetics, College of Agriculture, Odisha University of Agriculture and Technology, Bhubaneswar, 751003, India.

The toxic metalloid arsenic is known to cause liver and kidney injury in many humans and animals. The goal of this paper was to exemplify the antagonism of ginger against arsenic (As)-induced hepato-renal toxicity. In addition, the pathways Nrf2/Keap1 and NF/κB were studied to reveal the molecular mechanism of the stress. Read More

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Synergistic effects of arsenic and fluoride on oxidative stress and apoptotic pathway in Leydig and Sertoli cells.

Toxicology 2022 Jun 14;475:153241. Epub 2022 Jun 14.

Department of Biology, Faculty of Science, Istanbul University, Istanbul, Turkey.

Excessive intake of arsenic (As) and fluoride (F), which are present in underground drinking water, have adverse effects on human health, and especially on the male reproductive system. In this regard, it's critical to figure out how As and F affect Leydig and Sertoli cells, which are key cells in the male reproductive system. The goal of this study was to determine the synergistic effects of co-exposure of As and F, via drinking water, on Leydig and Sertoli cells, which are models for the male reproductive system, as well as the mechanisms underlying these effects in terms of oxidative damage and apoptosis. Read More

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Influence of humic acid and fluvic acid on the altered toxicities of arsenite and arsenate toward two freshwater algae.

Aquat Toxicol 2022 Jun 7;249:106218. Epub 2022 Jun 7.

Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, Institute of Environmental Research at Greater Bay Area, Guangzhou University, Guangzhou 510006, China. Electronic address:

Arsenic pollution in freshwater poses a serious threat to aquatic organisms. However, dissolved organic matter (DOM) in water can modulate arsenic environmental toxicity by either suppressing or promoting its bioaccumulation. In this study, we investigated the toxicity, bioaccumulation, and biotransformation of inorganic arsenic (arsenite As and arsenate As) combined with two types of DOM, i. Read More

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Preparation of freeze-dried bioluminescent bacteria and their application in the detection of acute toxicity of bisphenol A and heavy metals.

Food Sci Nutr 2022 Jun 11;10(6):1841-1853. Epub 2022 Apr 11.

School of Biology and Biological Engineering South China University of Technology Guangzhou China.

Current chemical analysis approaches for contaminants have failed to reveal their biotoxicity. Moreover, conventional bioassays are time consuming and exhibit poor repeatability. In this study, we performed the acute toxicity detection of various contaminants (chromium (Cr), cadmium (Cd), lead (Pb), arsenic (As), mercury (Hg), tin (Sn), nickel (Ni), and bisphenol A (BPA)) with four bioluminescent bacteria ( Q67, ,  T3, and  502) using a rapid, flexible, and low-cost bioassay. Read More

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Exploring Liposomes for Lung Cancer Therapy.

Crit Rev Ther Drug Carrier Syst 2022 ;39(4):1-47

Faculty of Pharmacy, Integral University, Lucknow-226026, India.

Cancer is referred to as a pleiotropic disease-causing approximately 9.6 million deaths in 2018. Among all cancers, lung cancer was the leading cause of death in 2017, and 12% of fatalities were alone due to lung cancer. Read More

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Nrf2/Keap1 pathway in countering arsenic-induced oxidative stress in mice after chronic exposure at environmentally-relevant concentrations.

Chemosphere 2022 Sep 6;303(Pt 3):135256. Epub 2022 Jun 6.

Institute of Soil and Water Resources and Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, China. Electronic address:

Contamination of drinking water by carcinogen arsenic (As) is of worldwide concern as its exposure poses potential threat to human health. As such, it is important to understand the mechanisms associated with As-induced toxicity to humans. The Nrf2/Keap1 signal pathway is one of the most important defense mechanisms in cells to counter oxidative stress; however, limited information is available regarding its role in countering As-induced stress in model animal mouse. Read More

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September 2022

Simultaneous removal of arsenate and arsenite in water using a novel functional halloysite nanotube composite.

Environ Sci Pollut Res Int 2022 Jun 8. Epub 2022 Jun 8.

Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control, Department of Environmental Science & Engineering, North China Electric Power University, Baoding, 071000, China.

This work aims at exploring a novel environment-friendly nanomaterial based on natural clay minerals for arsenic removal in aqueous samples. Halloysite nanotubes (HNTs) were selected as the substrate with Mn oxides loaded on the surface to enhance its arsenic adsorption ability and then grafted onto the SiO-coated FeO microsphere to get a just enough magnetic performance facilitating the material's post-treatment. The prepared composite ([email protected]@Mn-HNTs) was extensively characterized by various instruments including Fourier transform infrared spectroscope (FTIR), scanning electron microscope (SEM), transmission electron microscope (TEM), thermogravimetric analysis (TG), vibrating sample magnetometer (VSM), X-ray photoelectron spectroscope (XPS), and X-ray diffraction (XRD). Read More

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Endofungal Rhizobium species enhance arsenic tolerance in colonized host plant under arsenic stress.

Arch Microbiol 2022 Jun 8;204(7):375. Epub 2022 Jun 8.

Environmental Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhavan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.

Arsenic (As) is a toxic metalloid that is present in natural surroundings in many forms with severe consequences to sustainable agriculture and human health. Plant growth-promoting Rhizobia have been found involved in the induction of plant tolerance under various biotic and abiotic stresses. An endofungal Rhizobium species associated with arbuscular mycorrhizal fungi (AMF) Serendipita indica deploy beneficial role in the promotion of plant growth and tolerance against various biotic and abiotic stresses. Read More

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EVALUATION OF TRACE ELEMENT CONCENTRATIONS IN THE SERUM AND VIBRISSAE OF PERUVIAN PINNIPEDS (ARCTOCEPHALUS AUSTRALIS AND OTARIA BYRONIA).

J Wildl Dis 2022 Jun 6. Epub 2022 Jun 6.

Halmos College of Arts and Sciences, Nova Southeastern University, 8000 N Ocean Drive, Dania Beach, Florida 33004, USA.

Concentrations of 15 trace elements (aluminum, arsenic, cadmium, chromium, cobalt, copper, iron, lead, manganese, mercury, nickel, selenium, tin, vanadium, and zinc) were determined in vibrissae (whiskers) and serum of two sympatric pinniped species, the Peruvian fur seal population (PFS; Arctocephalus australis Peruvian subpopulation) and South American sea lion (SASL; Otaria byronia, at Punta San Juan, Peru during 2011-2019 sampling events. Element concentrations were 2-20 times higher in vibrissae than in serum. Vibrissae and serum concentrations of several elements, including aluminum, arsenic, and lead, suggest that environmental contaminants may affect the health of pinnipeds at Punta San Juan. Read More

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Co-cultivation as a Strategy to Reduce Food Chain-Mediated Arsenic Contamination in Human Beings.

Appl Biochem Biotechnol 2022 Jun 6. Epub 2022 Jun 6.

Department of Biotechnology, University of Engineering & Management, University Area, Plot No III, B/5, New Town Rd, Action Area III, Kolkata, West Bengal, 700160, India.

Arsenic (As) is a highly toxic metalloid present naturally in the earth's crust. In developing countries apart from drinking water, one major reason for arsenic toxicity among human beings is through contaminated crops and vegetables. The nutritional quality of the crops and vegetables grown in the arsenic-infested area gets compromised. Read More

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Metal(oid)s accumulation (Hg and As) and their biochemical effects in Halimione portulacoides (Ria de Aveiro, Portugal).

Mar Pollut Bull 2022 Jul 2;180:113804. Epub 2022 Jun 2.

CESAM - Centre for Environmental and Marine Studies, Biology Department, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.

For decades, mercury (Hg) and arsenic (As) were discharged into the Aveiro Lagoon. This study was designed to assess the natural attenuation process evolution by: (1) evaluating Hg and As concentration in sediments and in Halimione portulacoides, and assess the long-term evolution of a historically contaminated salt-marsh system; (2) evaluating the stress levels imposed by Hg and As, and the mechanisms triggered to squash oxidative damage. Concentrations of Hg and As in sediments varied considerably between sampling locations. Read More

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Analytical methods to determine and sense heavy metal pollutants using MXene and MXene-based composites: Mechanistic prophecy into sensing properties.

Chemosphere 2022 Sep 1;303(Pt 3):135166. Epub 2022 Jun 1.

School of Chemical Sciences, Central University of Gujarat, 382030, Gandhinagar, India. Electronic address:

The presence of heavy metal ions in the biosphere is of grave concern, as these are toxic and impact living organisms. Lack of pure drinking water can spread waterborne diseases like cholera, dysentery, typhoid, etc. The presence of heavy metals like arsenic and radioactive materials can cause cancer. Read More

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September 2022

Determination of arsenic, cadmium, mercury, lead and nickel as elemental impurities in atorvastatin calcium by inductively coupled mass spectrometer.

Eur J Mass Spectrom (Chichester) 2022 Jun 3:14690667221105835. Epub 2022 Jun 3.

Department of Pharmaceutical Analysis, 78997GITAM Institute of Pharmacy, Gandhi Institute of Technology and Management (GITAM) (Deemed to be University), Visakhapatnam, 530 045, Andhra Pradesh, India.

Atorvastatin calcium is employed as front-line treatment for cardiovascular diseases. According to the international conference on harmonization (ICH) guideline ICH Q3D, elemental impurities can come into drug products from various sources. These elemental impurities do not have any therapeutic benefit to the end-user. Read More

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Recent advances in arsenic mitigation in rice through biotechnological approaches.

Int J Phytoremediation 2022 Jun 2:1-9. Epub 2022 Jun 2.

Plant Stress Biology Laboratory, Institute of Environment and Sustainable Development, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Arsenic (As) is a major threat to the environment and human health due to its toxicity and carcinogenicity. Occurrence of alarming concentrations of As in water and soil leads to its bioaccumulation in crops which is a major health concern globally. Rice () is a staple food for a large population staying in As contaminated areas so, it is of utmost importance to reduce As levels in rice, especially grains. Read More

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Curcumin antagonizes inflammation and autophagy induced by arsenic trioxide through immune protection in duck spleen.

Environ Sci Pollut Res Int 2022 Jun 2. Epub 2022 Jun 2.

College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.

Arsenic is a toxic heavy metal widely found in the natural environment and has adverse effects on the health of waterfowl and human. Curcumin (CUR), a natural pigment of the golden spice turmeric, exhibits excellent anti-tumor, anti-inflammatory and anti-oxidant activities. But the effects of CUR on duck spleen exposed to arsenic remain largely unknown. Read More

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Is Arsenic Exposure a Risk Factor for Metabolic Syndrome? A Review of the Potential Mechanisms.

Front Endocrinol (Lausanne) 2022 16;13:878280. Epub 2022 May 16.

Department of Cognitive Neurosciences, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.

Exposure to arsenic in drinking water is a worldwide health problem. This pollutant is associated with increased risk of developing chronic diseases, including metabolic diseases. Metabolic syndrome (MS) is a complex pathology that results from the interaction between environmental and genetic factors. Read More

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Ethylene Suppresses Abscisic Acid, Modulates Antioxidant System to Counteract Arsenic-Inhibited Photosynthetic Performance in the Presence of Selenium in Mustard.

Front Plant Sci 2022 16;13:852704. Epub 2022 May 16.

Plant Physiology and Biochemistry Laboratory, Department of Botany, Aligarh Muslim University, Aligarh, India.

Arsenic (As) stress provokes various toxic effects in plants that disturbs its photosynthetic potential and hampers growth. Ethylene and selenium (Se) have shown regulatory interaction in plants for metal tolerance; however, their synergism in As tolerance through modification of the antioxidant enzymes and hormone biosynthesis needs further elaboration. With this in view, we investigated the impact of ethylene and Se in the protection of photosynthetic performance against As stress in mustard ( L. Read More

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Roles of humic substances redox activity on environmental remediation.

J Hazard Mater 2022 08 4;435:129070. Epub 2022 May 4.

School of Water Conservancy and Civil Engineering, Northeast Agricultural University, Harbin 150030, China; Joint Laboratory of Northeast Agricultural University and Max Planck Institute of Colloids and Interfaces (NEAU-MPICI), Harbin 150030, China. Electronic address:

Humic substances (HS) as representative natural organic matters and the most common organic compounds existing in the environment, has been applied to the treatment and remediation of environmental pollution. This review systematically introduces and summarizes the redox activity of HS for the remediation of environmental pollutants. For inorganic pollutants (such as silver, chromium, mercury, and arsenic), the redox reaction of HS can reduce their toxicity and mobilization, thereby reducing the harm of these pollutants to the environment. Read More

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Thiourea mediated ROS-metabolites reprogramming restores root system architecture under arsenic stress in rice.

J Hazard Mater 2022 08 27;435:129020. Epub 2022 Apr 27.

Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra 400085, India; Homi Bhabha National Institute, Mumbai 400094, India. Electronic address:

Arsenic (As) is a ubiquitous carcinogenic metalloid that enters into human food chain, through rice consumption. To unravel the conundrum of oxidative vs. reductive stress, the differential root-system architecture (RSA) was studied under As (a ROS producer) and thiourea (TU; a ROS scavenger) alone treatments, which indicated 0. Read More

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Understanding the Phytoremediation Mechanisms of Potentially Toxic Elements: A Proteomic Overview of Recent Advances.

Front Plant Sci 2022 6;13:881242. Epub 2022 May 6.

Center for Sustainable Development (CSD), College of Arts and Sciences, Qatar University, Doha, Qatar.

Potentially toxic elements (PTEs) such as cadmium (Cd), lead (Pb), chromium (Cr), and arsenic (As), polluting the environment, pose a significant risk and cause a wide array of adverse changes in plant physiology. Above threshold accumulation of PTEs is alarming which makes them prone to ascend along the food chain, making their environmental prevention a critical intervention. On a global scale, current initiatives to remove the PTEs are costly and might lead to more pollution. Read More

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