3,834 results match your criteria Toxicity Ammonia


Effect of ozone pretreatment on biogranulation with partial nitritation - Anammox two stages for nitrogen removal from mature landfill leachate.

J Environ Manage 2022 Sep 3;317:115470. Epub 2022 Jun 3.

Engelbart (Beijing) Eco-Tech Co., Ltd., Beijing, 101300, China.

Due to the extremely low C/N ratio, high concentration of ammonia nitrogen and refractory organic matter of mature landfill leachate (MLL), appropriate processes should be selected to effectively remove nitrogen and reduce disposal costs. Partial nitritation (PN) and anaerobic ammonia oxidation (AMX) have been used as the main nitrogen removal processes for MLL, and the sludge granulation in PN and AMX processes could contribute to high biological activity, good sedimentation performance, and stable resistance to toxicity. In this study, the O-PN-AMX biogranules process was selected to effectively remove nitrogen from MLL without carbon addition and pH adjustment. Read More

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September 2022

Toxic Metabolites and Inborn Errors of Amino Acid Metabolism: What One Informs about the Other.

Metabolites 2022 Jun 8;12(6). Epub 2022 Jun 8.

Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

In inborn errors of metabolism, such as amino acid breakdown disorders, loss of function mutations in metabolic enzymes within the catabolism pathway lead to an accumulation of the catabolic intermediate that is the substrate of the mutated enzyme. In patients of such disorders, dietarily restricting the amino acid(s) to prevent the formation of these catabolic intermediates has a therapeutic or even entirely preventative effect. This demonstrates that the pathology is due to a toxic accumulation of enzyme substrates rather than the loss of downstream products. Read More

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Exogenous Hemin alleviates cadmium stress in maize by enhancing sucrose and nitrogen metabolism and regulating endogenous hormones.

Int J Phytoremediation 2022 Jun 22:1-13. Epub 2022 Jun 22.

College of Agriculture, Northeast Agricultural University, Harbin, China.

Cadmium (Cd) stress restricts maize growth and productivity severely. We aimed to investigate the effects of Hemin on the metabolism of sucrose and nitrogen and endogenous hormones in maize under cadmium stress. Maize varieties 'Tiannong 9' (cadmium tolerant) and 'Fenghe 6' (cadmium sensitive) were grown in nutrient solutions to study the effects of Hemin on maize physiological and ecological mechanisms under cadmium stress. Read More

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Improved mineralization and total nitrogen reduction by combination of electro-reduction and electro-oxidation for nitrophenol removal.

Chemosphere 2022 Jun 18;305:135400. Epub 2022 Jun 18.

State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing, 210023, PR China; Nanjing Innovation Center for Environmental Protection Industry Co., Ltd., Nanjing, 211102, PR China.

In this work, p-Nitrophenol (p-NP) was electro-chemically removed by using a prepared CoO/Ti cathode and a BDD anode to achieve the simultaneous reduction of total organic carbon (TOC), total nitrogen (TN) and toxicity. The prepared CoO/Ti cathode showed higher electro-activity than the Ti cathode towards p-NP reduction with the removal rate higher than 90.6% but without mineralization. Read More

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Gas- and Particle-Phase Amide Emissions from Cooking: Mechanisms and Air Quality Impacts.

Environ Sci Technol 2022 Jun 7. Epub 2022 Jun 7.

Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON M5S 3E5, Canada.

The high-temperature cooking of protein-rich foods represents an important but poorly constrained source of nitrogen-containing gases and particles to indoor and outdoor atmospheres. For example, panfrying meat may form and emit these nitrogen-containing compounds through complex chemistry occurring between heated proteins and cooking oils. Here, we simulate this cooking process by heating amino acids together with triglycerides. Read More

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Metabolomic Profiling Analysis of Physiological Responses to Acute Hypoxia and Reoxygenation in Juvenile Qingtian Paddy Field Carp .

Front Physiol 2022 20;13:853850. Epub 2022 May 20.

Centre for Research on Environmental Ecology and Fish Nutrition of the Ministry of Agriculture, Shanghai Ocean University, Shanghai, China.

The Qingtian paddy field carp () is a local carp cultivated in the rice field of Qingtian county, Zhejiang province, China. The paddy field environment is distinct from the pond environment. Due to the inability to artificially increase oxygen, the dissolved oxygen greatly changes during the day. Read More

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Foxtail millet [Setaria italica (L.) Beauv.] over-accumulates ammonium under low nitrogen supply.

Plant Physiol Biochem 2022 May 27;185:35-44. Epub 2022 May 27.

MOE Key Laboratory of Plant-Soil Interactions, Department of Plant Nutrition, China Agricultural University, Beijing, 100193, China. Electronic address:

Nitrogen (N) deficiency is a primary limiting factor for crop production worldwide. Previously, we reported root system architectural modifications of hydroponically cultured foxtail millet [Setaria italica (L.) Beauv. Read More

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Ammonia level influences the assembly of dissimilatory nitrate reduction to ammonia bacterial community in soils under different heavy metal remediation treatments.

Sci Total Environ 2022 Sep 31;838(Pt 3):156393. Epub 2022 May 31.

State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Arable Land Conservation (Middle and Lower Reaches of Yangtze River), Ministry of Agriculture and Rural Affairs, College of Resources and Environment, Huazhong Agricultural University, Wuhan 430070, China.

Heavy metal remediation treatments might influence functional microbial community assembly. Dissimilatory nitrate reduction to ammonia (DNRA) contributes to the nitrogen retention processes in soil ecosystems. We assumed that remediation might reduce heavy metal toxicity and increase some available nutrients for the DNRA microbes, thus balancing the deterministic and stochastic process for DNRA community assembly. Read More

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September 2022

Liver transcriptome analysis reveals biological pathways and transcription factors in response to high ammonia exposure.

Inhal Toxicol 2022 1;34(7-8):219-229. Epub 2022 Jun 1.

Key Laboratory of Smart Animal Farming Technology, Ministry of Agriculture, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.

Ammonia is a toxic gas that not only causes environmental pollution, but also is harmful to human health after inhalation. Liver is an important detoxification organ that can convert external or metabolized toxic substances into nontoxic substances. However, the toxic effects of ammonia exposure on livers have not been well studied. Read More

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Nattokinase attenuates bisphenol A or gamma irradiation-mediated hepatic and neural toxicity by activation of Nrf2 and suppression of inflammatory mediators in rats.

Environ Sci Pollut Res Int 2022 Jun 1. Epub 2022 Jun 1.

Radiation Biology Research, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, Nasr City, Cairo, 11787, Egypt.

Nattokinase (NK), a protease enzyme produced by Bacillus subtilis, has various biological effects such as lipid-lowering activity, antihypertensive, antiplatelet/anticoagulant, and neuroprotective effects. Exposure to environmental toxicants such as bisphenol A (BPA) or γ-radiation (IR) causes multi-organ toxicity through several mechanisms such as impairment of oxidative status, signaling pathways, and hepatic and neuronal functions as well as disruption of the inflammatory responses. Therefore, this study is designed to evaluate the ameliorative effect of NK against BPA- or IR-induced liver and brain damage in rats. Read More

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Water toxicants: a comprehension on their health concerns, detection, and remediation.

Environ Sci Pollut Res Int 2022 May 27. Epub 2022 May 27.

Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, 142 001, Punjab, India.

Water is an essential moiety for the human use since a long time. Availability of good-quality water is very essential, as it is used in almost all the industrial, agricultural, and household activities. However, several factors such as increased urbanization and industrialization, extensive use of chemicals, natural weathering of rocks, and human ignorance led to incorporation of enormous toxicants into the water. Read More

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Evaluation of Growth Performance, Nitrogen Balance and Blood Metabolites of Mutton Sheep Fed an Ammonia-Treated Aflatoxin B1-Contaminated Diet.

Toxins (Basel) 2022 05 23;14(5). Epub 2022 May 23.

College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.

Experiments were conducted to evaluate the effects of an aflatoxin B1 (AFB1)-contaminated diet treated with ammonia on the diet detoxification and growth performance, nutrient digestibility, nitrogen utilization, and blood metabolites in sheep. Twenty-four female mutton sheep with an initial body weight of 50 ± 2.5 kg were randomly assigned to one of three groups: (1) control diet (C); (2) aflatoxin diet (T; control diet supplemented with 75 μg of AFB1/kg of dry matter); and (3) ammoniated diet (AT; ammoniated aflatoxin diet). Read More

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The inhibitory effects and underlying mechanism of high ammonia stress on sulfide-driven denitrification process.

Chemosphere 2022 Sep 23;303(Pt 2):135093. Epub 2022 May 23.

College of Chemical and Biological Engineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Zhejiang University, Hangzhou, 310027, China; Institute of Zhejiang University-Quzhou, Quzhou, 324000, China. Electronic address:

Sulfide-driven denitrification (SD) process has been widely studied for treating wastewater containing sulfate and ammonia in recent years. But influence of high ammonia stress on the SD process and microbial community remained unclear. In this work, a series of tests were conducted to investigate effects of different ammonia stress (200-3000 mg-total ammonia nitrogen (TAN)/L) on denitrification efficiency, byproduct accumulation and microbial community of the SD process. Read More

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September 2022

Acute exposure to polystyrene nanoplastics impairs skin cells and ion regulation in zebrafish embryos.

Aquat Toxicol 2022 Jul 19;248:106203. Epub 2022 May 19.

Department of Life Science, School of Life Science, National Taiwan Normal University, Taipei, Taiwan; Biodiversity Program, Taiwan International Graduate Program, Biodiversity Research Center, Academia Sinica and National Taiwan Normal University, Taipei, Taiwan. Electronic address:

The presence of nanoplastics in aquatic environments is a global problem. Accumulating evidence shows that nanoplastics can accumulate in fish and influence internal organs. However, it is still unknown if nanoplastics can impair skin cells (keratinocytes and ionocytes), which play critical roles in maintaining body fluid homeostasis. Read More

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Protective effects of dietary supplementation of probiotic Bacillus licheniformis Dahb1 against ammonia induced immunotoxicity and oxidative stress in Oreochromis mossambicus.

Comp Biochem Physiol C Toxicol Pharmacol 2022 May 21:109379. Epub 2022 May 21.

Biomaterials and Biotechnology in Animal Health Lab, Department of Animal Health and Management, Science Campus 6(th) Floor, Alagappa University, Karaikudi 630004,Tamil Nadu, India. Electronic address:

The goal of this study was to assess the efficacy of probiotics in mitigating ammonia-induced toxicity in fish. Fish were divided into four groups: control, only probiotic, only ammonia, and combined ammonia + probiotic. For 8 weeks, the Oreochromis mossambicus were exposed to waterborne ammonia at 1. Read More

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Mercury stress tolerance in wheat and maize is achieved by lignin accumulation controlled by nitric oxide.

Environ Pollut 2022 Aug 18;307:119488. Epub 2022 May 18.

National Key Laboratory of Wheat and Maize Crop Science, Key Laboratory of Regulating and Controlling Crop Growth and Development Ministry of Education, Henan Agricultural University, Zhengzhou, Henan, 450046, China. Electronic address:

Nitric oxide (NO) is an important phytohormone for plant adaptation to mercury (Hg) stress. The effect of Hg on lignin synthesis, NO production in leaf, sheath and root and their relationship were investigated in two members of the grass family - wheat and maize. Hg stress decreased growth and lignin contents, significantly affected phenylpropanoid and monolignol pathways (PAL, phenylalanine ammonia-lyase; 4-coumarate: CoA ligase, 4CL; cinnamyl alcohol dehydrogenase, CAD), with maize identified to be more sensitive to Hg stress than wheat. Read More

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The effects of ammonia acclimation on biogas recovery and the microbial population in continuous anaerobic digestion of swine manure.

Environ Res 2022 Sep 16;212(Pt D):113483. Epub 2022 May 16.

School of Civil and Environmental Engineering, Yonsei University, Seoul 03722, Republic of Korea. Electronic address:

This study investigated the ammonia toxicity and the acclimation of anaerobic microbiome in continuous anaerobic digestion of swine manure using unacclimated inoculum. When the total ammonia nitrogen concentration (TAN) reached 2.5 g N/L, the methane yield decreased from 254. Read More

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September 2022

Thymol ameliorated neurotoxicity and cognitive deterioration in a thioacetamide-induced hepatic encephalopathy rat model; involvement of the BDNF/CREB signaling pathway.

Food Funct 2022 Jun 6;13(11):6180-6194. Epub 2022 Jun 6.

Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

In the present study, we aimed to delineate the neuroprotective potential of thymol (THY) against neurotoxicity and cognitive deterioration induced by thioacetamide (TAA) in an experimental model of hepatic encephalopathy (HE). Rats received TAA (100 mg kg, intraperitoneally injected, three times per week) for two weeks. THY (30 and 60 mg kg), and Vit E (100 mg k) were administered daily by oral gavage for 30 days after HE induction. Read More

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Effect of Stability of Two-Dimensional (2D) Aminoethyl Methacrylate Perovskite Using Lead-Based Materials for Ammonia Gas Sensor Application.

Polymers (Basel) 2022 Apr 30;14(9). Epub 2022 Apr 30.

Institute for Artificial Intelligence and Big Data, Universiti Malaysia Kelantan, City Campus, Kota Bharu 16100, Malaysia.

Changes in physical properties of (HC=C(CH)COCHCHNH)PbICl and (HC=C(CH)COCHCHNH)Pb(NO)Cl (2D) perovskite materials from iodide-based (-AMP) and nitrate-based (-AMP) leads were investigated at different durations (days) for various storage conditions. UV-Vis spectra of both samples showed an absorption band of around 420 nm due to the transition of to π* of ethylene (C=C) and amine (NH). XRD perovskite peaks could be observed at approximately 25. Read More

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A review on MXene and its nanocomposites for the detection of toxic inorganic gases.

Chemosphere 2022 Sep 10;302:134933. Epub 2022 May 10.

Universidad Autónoma de Chile, Chile.

In the search of the viable candidate for the sensing of pollutant gases, two-dimensional (2D) material transition metal carbides (MXenes) have attracted immense attention due to their outstanding physical and chemical properties for sensing purposes. The formation of unique 2D layered structure with high conductivity, large mechanical strength, and high adsorption properties furnish their strong interactions with gaseous molecules, which holds a promising place for developing ideal gas sensing devices. This review looks at recent achievements in diversified MXenes, with a focus gaining on in-depth understanding of MXene-based materials in room temperature inorganic gas sensors through both theoretical and experimental studies. Read More

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September 2022

[Toxicity mechanism of Rhododendri Mollis Flos: based on serum metabolomics and network toxicology].

Zhongguo Zhong Yao Za Zhi 2022 Apr;47(7):1932-1941

State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China.

This study aims to explore the toxicity mechanism of Rhododendri Mollis Flos(RMF) based on serum metabolomics and network toxicology. The toxic effect of RMF on normal rats was evaluated according to the symptoms, serum biochemical indexes, and histopathology. Serum metabolomics was combined with multivariate statistical analysis to search endogenous differential metabolites and related metabolic pathways. Read More

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Application of proteomics and metabolomics to assess ammonia stress response and tolerance mechanisms of juvenile ornate rock lobster Panulirus ornatus.

Sci Total Environ 2022 Sep 6;837:155751. Epub 2022 May 6.

Key Laboratory for Sustainable Utilization of Marine Fisheries Resources, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, PR China; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, PR China. Electronic address:

Ammonia is a common pollutant in the aquatic ecosystem and closed aquaculture systems. It may pose a threat to the lobster growth, reproduction and survival. However, there is lack of research of the mechanisms on the toxic effects ammonia at molecular levels. Read More

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September 2022

Current technologies and future perspectives for the treatment of complex petroleum refinery wastewater: A review.

Bioresour Technol 2022 Jul 5;355:127263. Epub 2022 May 5.

Department of Chemical Engineering, Institute of Chemical Technology, Mumbai-Indian Oil Odisha Campus, Bhubaneswar, Odisha 751013, India; Department of Chemical Engineering, Indian Institute of Petroleum and Energy (IIPE), Visakhapatnam, Andhra Pradesh 530003, India. Electronic address:

Petroleum refinery wastewater (PRW) is a complex mixture of hydrocarbons, sulphides, ammonia, oils, suspended and dissolved solids, and heavy metals. As these pollutants are toxic and recalcitrant, it is essential to address the above issue with efficient, economical, and eco-friendly technologies. In this review, initially, an overview of the characteristics of wastewater discharged from different petroleum refinery units is discussed. Read More

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Comparison of inhibitory roles on nitrite-oxidizing bacteria by hydroxylamine and hydrazine during the establishment of partial nitrification.

Bioresour Technol 2022 Jul 5;355:127271. Epub 2022 May 5.

School of Water and Environment, Chang'an University, Xi'an 710064, Shaanxi, China; Key Laboratory of Subsurface Hydrology and Ecological Effect in Arid Region (Chang'an University), Ministry of Education, Xi'an 710064, Shaanxi, China. Electronic address:

The inhibitory roles of hydroxylamine (NHOH) and hydrazine (NH) on nitrite-oxidizing bacteria were investigated in a comparative study. The results showed that nitrite accumulation was achieved by adding 5 mg-N/L NHOH or NH to two parallel sequencing batch reactors, with nitrite accumulation rate reaching 95.83% and 86. Read More

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Electrochemical oxidation of landfill leachate using boron-doped diamond anodes: pollution degradation rate, energy efficiency and toxicity assessment.

Environ Sci Pollut Res Int 2022 Apr 30. Epub 2022 Apr 30.

Faculty of Civil and Environmental Engineering, Gdansk University of Technology, 11/12 Narutowicza St, 80-233, Gdansk, Poland.

Electrochemical oxidation (EO), due to high efficiency and small carbon footprint, is regarded as an attractive option for on-site treatment of highly contaminated wastewater. This work shows the effectiveness of EO using three boron-doped diamond electrodes (BDDs) in sustainable management of landfill leachate (LL). The effect of the applied current density (25-100 mA cm) and boron doping concentration (B/C ratio: 500 ppm, 10,000 ppm and 15,000 ppm) on the performance of EO was investigated. Read More

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Understanding the slight inhibition of high As(III) stress on nitritation process: Insights from arsenic speciation and microbial community analyses.

J Hazard Mater 2022 08 18;435:128957. Epub 2022 Apr 18.

Institute of Environmental Engineering, School of Metallurgy and Environment, Central South University, Changsha 410083, China; Chinese National Engineering Research Center for Control & Treatment of Heavy Metal Pollution, Changsha 410083, China; Water Pollution Control Technology Key Lab of Hunan Province, Changsha 410004, China. Electronic address:

Nitritation process with ammonia-oxidizing bacteria frequently suffers inhibition from heavy metals in industrial wastewater treatment. However, As(III), one of the most toxic metalloids, showed slight inhibition though the arsenic accumulation content in the sludge reached 91.8 mg L in this study. Read More

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Toxicity of Wildland Fire-Fighting Chemicals in Pulsed Exposures to Rainbow Trout and Fathead Minnows.

Environ Toxicol Chem 2022 Jul 27;41(7):1711-1720. Epub 2022 May 27.

Columbia Environmental Research Center, US Geological Survey, Columbia, Missouri, USA.

Intrusions of fire-fighting chemicals in streams can result from containment and suppression of wildfires and may be harmful to native biota. We investigated the toxicity of seven current-use fire-fighting chemicals to juvenile rainbow trout (Oncorhynchus mykiss) and fathead minnows (Pimephales promelas) by simulating chemical intrusions under variable field conditions to provide insights into the potential damage these chemicals may cause in waterways. In three separate attenuated exsposure assays in which chemical concentration decreased throughout the 96-h exposure period, we varied water flow rate, water hardness, and initial concentration of test chemical. Read More

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Ammonia exposure by intratracheal instillation causes severe and deteriorating lung injury and vascular effects in mice.

Inhal Toxicol 2022 22;34(5-6):145-158. Epub 2022 Apr 22.

Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.

Objective: Ammonia (NH) is a corrosive alkaline gas that can cause life-threatening injuries by inhalation. The aim was to establish a disease model for NH-induced injuries similar to acute lung injury (ALI) described in exposed humans and investigate the progression of lung damage, respiratory dysfunction and evaluate biomarkers for ALI and inflammation over time.

Methods: Female BALB/c mice were exposed to an NH dose of 91. Read More

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Effects of acute ammonia nitrogen exposure on metabolic and immunological responses in the Hong Kong oyster Crassostrea hongkongensis.

Ecotoxicol Environ Saf 2022 Jun 18;237:113518. Epub 2022 Apr 18.

Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, China. Electronic address:

Ammonia nitrogen, a major oxygen-consuming pollutant in the environment, can adversely affect aquatic organisms such as fish, bivalves, and crustaceans. We investigated the toxic effects of ammonia nitrogen on the Hong Kong oyster, Crassostrea hongkongensis, using flow cytometry and H nuclear magnetic resonance metabolomics. Exposure to ammonia nitrogen caused time- and concentration-dependent alterations in various immune parameters in hemocytes and impaired the metabolic profiles of the gills. Read More

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Interaction of TiO nanoparticles with soil: Effect on microbiological and chemical traits.

Chemosphere 2022 Aug 18;301:134629. Epub 2022 Apr 18.

School of Agricultural Biotechnology, College of Agriculture, Punjab Agricultural University, Ludhiana, 141004, India.

Titanium dioxide (TiO) nanoparticles (NPs) are the most widely used nanomaterials and their expanding use raises concerns about their impacts on soil ecosystems and functioning. The present study evaluates the potential impacts of TiO NPs applied at low doses (0, 1.0, 2. Read More

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