J Fr Ophtalmol 2022 May 13;45(5):495-503. Epub 2022 Apr 13.
Service d'ophtalmologie, CRMR Ophtara, hôpital universitaire Necker-Enfants-Malades, hôpitaux Paris Centre, AP-HP, Paris, France; Faculté de médecine, université de Paris, Paris, France; Centre Borelli, UMR 9010 CNRS-ENS Paris Saclay, SSA, Université de Paris, Gif sur Yvette, France.
While treatment of pulmonary infections by Mycobacterium tuberculosis is currently only rarely the cause of iatrogenic complications, treatment of atypical mycobacterial infections often requires prolonged treatment duration, which can lead to toxic optic neuropathies. This review summarizes the indications for such prolonged treatment and risk factors for toxic optic neuropathies when using ethambutol, isoniazid and/or linezolid and proposes customized screening recommendations. Read More