167 results match your criteria Toxic Anterior Segment Syndrome


Cases of toxic anterior segment syndrome after primary pterygium surgery.

Int Ophthalmol 2022 May 14. Epub 2022 May 14.

Gaziantep University, Gaziantep, Turkey.

Purpose: Toxic anterior segment syndrome (TASS) is an acute, sterile, inflammatory reaction of the anterior segment after intraocular surgeries. We aimed to report an outbreak of TASS which occurred following pterygium surgeries.

Methods: A case series. Read More

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Surgical Approach in Intraocular Tumors

Turk J Ophthalmol 2022 04;52(2):125-138

Ankara University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey

Surgery in intraocular tumors is done for excision/biopsy and the management of complications secondary to the treatment of these tumors. Excision/biopsy of intraocular tumors can be done via fine-needle aspiration biopsy (FNAB), transretinal biopsy (TRB), partial lamellar sclerouvectomy (PLSU), and endoresection. FNAB, TRB, and PLSU can be used in tumors that cannot be diagnosed by clinical examination and other ancillary testing methods. Read More

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Reduced corneal endothelial cell density after toxic anterior segment syndrome (TASS) caused by inadvertent intraocular ointment migration: A case report.

Int J Surg Case Rep 2022 Apr 3;94:107029. Epub 2022 Apr 3.

Department of Ophthalmology, University Hospital and Faculty of Medicine, Autonomous University of Nuevo León (UANL), Monterrey, 64460, Mexico.

Introduction And Importance: Toxic anterior segment syndrome (TASS) is an acute sterile inflammation of the anterior segment which may occur after surgery. This case presents endothelial cell density (ECD) loss due to months of TASS caused by intraocular migration of ocular ointment. The chronicity of this case and the clinical consequences are rare in the literature. Read More

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Influence of Fine Management Combined With PDCA Cycle Method on Disinfection Qualified Rate and Performance Grade of Ophthalmic Precision Instruments.

Front Surg 2022 15;9:856312. Epub 2022 Mar 15.

Central Sterile Supply Department, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.

Objective: The aim of this study is to explore the influence of fine management combined with the plan-do-check-action (PDCA) cycle method on the management of ophthalmic precision instruments.

Methods: The ophthalmic precision instruments centralized in the disinfection supply room of our hospital were selected as the research objects and divided into groups A and B. Traditional instrument management method was adopted in group A, and fine management combined with the PDCA cycle method based on the group A was adopted in group B. Read More

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Diffuse Corneal Edema after Uneventful Pterygium Surgery: Toxic Anterior Segment Syndrome or Toxic Keratopathy?

Turk J Ophthalmol 2022 02;52(1):69-71

İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey

A 29-year-old woman was referred to our department for corneal edema after uneventful pterygium excision surgery with conjunctival autografting. She was prescribed topical dexamethasone and showed a complete response within 2 weeks of treatment. Specular microscopic examination revealed severe endothelial cell loss in the operated eye. Read More

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February 2022

Toxic anterior segment syndrome following EyePCL implantation in a hyperopic patient.

J Fr Ophtalmol 2022 Mar 25;45(3):272-276. Epub 2022 Jan 25.

Centre Ophtalmologique, Place de l'Etoile, Luxembourg; Centre Laser Monterey, Luxembourg.

Introduction: Toxic anterior segment syndrome (TASS) is a rare but serious complication of anterior segment surgery characterised by an acute sterile inflammation. The ICL implantation has gained popularity for the correction of moderate and high ametropias in cases where classical keratorefractive procedures are contraindicated.

Objective: The purpose of this case report is to present the evolution and management of toxic anterior segment syndrome after EyePCL implantation in a 19 year old hyperopic male patient. Read More

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All India Ophthalmological Society (AIOS) Task Force guidelines to prevent intraocular infections and cluster outbreaks after cataract surgery.

Indian J Ophthalmol 2022 Feb;70(2):362-368

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Infectious endophthalmitis is a serious and vision-threatening complication of commonly performed intraocular surgeries such as cataract surgery. The occurrence of endophthalmitis can result in severe damage to the uveal and other ocular tissues even among patients undergoing an uncomplicated surgical procedure. If the infections result from common factors such as surgical supplies, operative or operation theater-related risks, there can be a cluster outbreak of toxic anterior segment syndrome (TASS) or infectious endophthalmitis, leading to several patients having an undesirable outcome. Read More

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February 2022

Barium-induced toxic anterior segment syndrome.

Eur J Ophthalmol 2021 Dec 30:11206721211069223. Epub 2021 Dec 30.

Department of Ophthalmology, Graduate School of Medicine, 38637Osaka University, Osaka, Japan.

Toxic anterior segment syndrome (TASS) is a rapid-onset inflammation of the eye following uneventful ocular surgery. We report a case of TASS following Baerveldt glaucoma implant (BGI) surgery. Inductively coupled plasma-mass spectrometry (ICP-MS) identified barium in the eye and in the eluate from the bleb of the BGI. Read More

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December 2021

Immediately sequential bilateral cataract surgery (ISBCS) adapted protocol during COVID-19.

Can J Ophthalmol 2021 Nov 9. Epub 2021 Nov 9.

Department of Ophthalmology, University of Alberta, Edmonton, Alta. Electronic address:

Objective: To describe the steps, hurdles, and recommendations for implementation of the immediately sequential bilateral cataract surgery (ISBCS) evidence-based protocol at a high-volume Canadian tertiary care centre.

Design: Quality-improvement study.

Participants: A total of 406 patients who underwent ISBCS from July 2020 to December 2020. Read More

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November 2021

Lens-induced hypopyon uveitis as the presenting manifestation of posterior lens nucleus dislocation following pars-plana vitrectomy: case report.

J Ophthalmic Inflamm Infect 2021 Nov 16;11(1):42. Epub 2021 Nov 16.

Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, 1st June Street, Fattouma Bourguiba University Hospital, 5000, Monastir, Tunisia.

A 57-year-old otherwise healthy male presented to our department seven days following uneventful pars-plana vitrectomy with gas tamponade for a superior bullous retinal detachment in the left eye. Ophthalmic examination revealed anterior segment inflammation with hypopyon and fibrinous exudate. Intra-ocular pressure was 28 mmHg. Read More

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November 2021

Toxic Posterior Segment Syndrome Presenting as Occlusive Retinal Vasculitis following Vitreoretinal Surgery.

J Curr Ophthalmol 2021 Jul-Sep;33(3):345-348. Epub 2021 Oct 22.

Smt. Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To report a rare retinal manifestation of toxic posterior segment syndrome following vitreoretinal surgery.

Methods: In this case series, we report three cases of rhegmatogenous retinal detachment for which pars plana vitrectomy with silicone oil injection was done. All three patients developed an intense anterior chamber reaction along with occlusive vasculitis-like fundus picture. Read More

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October 2021

Sutureless Amniotic Membrane (ProKera®) and Intravenous Immunoglobulin in the Management of Ocular Complications of Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis Overlap.

Cureus 2021 Aug 8;13(8):e16989. Epub 2021 Aug 8.

Ophthalmology, Anterior Segment Division, Prince Sultan Military Medical City, Riyadh, SAU.

Purpose: To report a case of Stevens-Johnson syndrome-toxic epidermal necrolysis (SJS-TEN) overlap, with severe acute ocular manifestations successfully managed with sutureless Amniotic Membrane device ProKera (Bio-Tissue, Inc., Miami, FL) and topical steroids, followed by late complications that were successfully managed with intravenous immunoglobulin (IVIG) therapy.

Observations: A 24-year-old lady, known case of epilepsy, admitted to the burn unit with SJS-TEN overlap attributed to a recent change of her anti-convulsant therapy, with severe ocular manifestations, inability to open both eyes, and poor visual acuity. Read More

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Late-onset toxic anterior segment syndrome after possible aluminum-contaminated and silicon-contaminated intraocular lens implantation.

J Cataract Refract Surg 2022 Apr;48(4):443-448

From the Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium (Wijnants, Delbeke, Van Calster, Beerlandt, Nijs, Saelens); Oogartsenpraktijk Tervuren, Tervuren, Belgium (Beerlandt); Oogartsenassociatie Maasmechelen, Maasmechelen, Belgium (Nijs); John A. Moran Eye Center, University of Utah, Salt Lake City, Utah (Werner, Mamalis).

Purpose: To describe an outbreak of late-onset toxic anterior segment syndrome (TASS) after the implantation of a specific hydrophilic acrylic intraocular lens (IOL).

Setting: University Hospitals of Leuven, Belgium.

Design: Retrospective, single-center, observational study. Read More

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Immediately sequential bilateral cataract surgery: an academic teaching center's experience.

J Cataract Refract Surg 2022 Mar;48(3):310-316

From the Department of Ophthalmology, Hôpital du Saint-Sacrement, Quebec City, Canada (Qi, Hébert, You, Légaré, Mercier), the Department of Medicine, Université Laval, Quebec City, Canada (Qi, Arsenault, Hébert, You, Légaré, Mercier), and the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada (Arshinoff).

Purpose: To evaluate the safety and outcomes of immediately sequential bilateral cataract surgery (ISBCS) at a Canadian academic teaching center.

Setting: Tertiary university teaching hospital of Laval University, Quebec City, Canada.

Design: Retrospective cohort study. Read More

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Adverse events associated with femtosecond laser-assisted cataract surgery reported to the MAUDE database.

J Cataract Refract Surg 2022 Feb;48(2):168-172

From the Department of Ophthalmology, Weill Cornell Medicine, New York, New York.

Purpose: To report real-world complications associated with femtosecond laser-assisted cataract surgery (FLACS).

Setting: Deidentified database.

Design: Retrospective review. Read More

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February 2022

Toxic Anterior Segment Syndrome After an Uncomplicated Vitrectomy With Epiretinal Membrane Peeling.

Authors:
Piotr Kanclerz

Cureus 2021 Apr 13;13(4):e14464. Epub 2021 Apr 13.

Ophthalmology, Hygeia Clinic, Gdansk, POL.

Infectious endophthalmitis is the most devastating complication of eye surgery and is associated with severe inflammation of ocular tissues. This study aimed to present a similar condition, a case of toxic anterior segment syndrome (TASS) after an uncomplicated vitrectomy. A 69-year-old woman presented with epiretinal membrane and underwent 25-gauge pars plana vitrectomy with membrane peeling in her left eye. Read More

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Report of a Cluster of Cases of Toxic Anterior-segment Syndrome After Implantation of a Specific Intraocular Lens Model.

Am J Ophthalmol 2021 08 5;228:1-7. Epub 2021 Apr 5.

From the Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo.

Purpose: To report a cluster of cases of toxic anterior-segment syndrome (TASS) in eyes implanted with a specific foldable acrylic intraocular lens (IOL) model.

Design: Retrospective case series.

Methods: The medical records were reviewed for 7 eyes of 4 patients diagnosed with TASS after cataract surgery at Shimane University and Matsue Red Cross Hospital between July and November 2020. Read More

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Severe Intraocular Inflammation following Hydrophilic Acrylic Phakic Intraocular Lens Implantation in A Case with Concealed History of COVID-19: A Case Report and Literature Review.

Ocul Immunol Inflamm 2021 May 1;29(4):662-665. Epub 2021 Apr 1.

Department of Ophthalmology, Faculty of Medicine, Pamukkale University, Kinikli, Turkey.

: To firstly present management of toxic anterior segment syndrome (TASS) and possible postoperative endophthalmitis (POE) after implantation of a new hydrophilic-acrylic posterior chamber (PC) phakic intraocular lens (pIOL) in a case with undeclared history of COVID-19. A 21-year-old male without known disease represented severe anterior chamber inflammation (hypopyon), poor vision and corneal edema without vitreous involvement (TASS) at 24-hours after PC-pIOL implantation for unilateral high myopia (amblyopic). Preoperative best-corrected visual acuity (BCVA) was 0. Read More

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Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature.

Case Rep Ophthalmol Med 2021 2;2021:5526097. Epub 2021 Mar 2.

Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, USA.

A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after oral and topical fluoroquinolone exposure. Additionally, we review the literature on safety, efficacy, and appropriate dosing of intracameral antibiotics with a focus on moxifloxacin. Read More

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Intracameral r-tPA for the management of severe fibrinous reactions in TASS after cataract surgery.

Eur J Ophthalmol 2022 Jan 15;32(1):200-204. Epub 2021 Mar 15.

Ophthalmology Department, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Background: To describe the use of intracameral recombinant tissue plasminogen activator (r-tPA) in the treatment of severe fibrinous reactions in toxic anterior segment syndrome (TASS) after cataract surgery.

Methods: A case series of 59 eyes of 59 patients with severe fibrinous anterior chamber reaction following cataract surgery who received intracameral r-tPA (25 µg/0.1 ml). Read More

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January 2022

Early Complications With Preloaded Descemet Membrane Endothelial Keratoplasty Are Not Dependent on Optisol-GS Washout or Trypan Blue Restaining.

Cornea 2021 Nov;40(11):1402-1405

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR.

Purpose: To describe the intraoperative and early postoperative complications using preloaded Descemet membrane endothelial keratoplasty (DMEK) grafts with intraocular injection of the graft in Optisol-GS and omission of trypan blue restaining.

Methods: This is a retrospective case series of 132 consecutive eyes with Fuchs endothelial dystrophy or endothelial failure who underwent DMEK using preloaded donor tissue prepared as previously described. The graft was not restained with trypan blue by the surgeon, and Optisol-GS was injected with the graft into the eye instead of being rinsed from the injector. Read More

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November 2021

Postoperative Endophthalmitis and Toxic Anterior Segment Syndrome Prophylaxis: 2020 Update.

Ann Transl Med 2020 Nov;8(22):1548

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Improved surgical techniques have led to an increase in the number of outpatient ophthalmic procedures. In spite of decreased surgical times and overall improved outcomes, endophthalmitis remains one of the most severe complications of ophthalmic surgery. Although there are well known risk factors for postoperative endophthalmitis, some prophylaxis strategies remain controversial. Read More

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November 2020

Occlusion of AquaPORT Flow in a Case of Toxic Anterior Segment Syndrome Following Implantable Collamer Lens Surgery Causing Severe Pupillary Block.

J Refract Surg 2020 Dec;36(12):856-859

Purpose: To present a case where following Implantable Collamer Lens (ICL) implantation the patient developed toxic anterior segment syndrome (TASS) with a subsequent pupillary block as a consequence of the occlusion of the AquaPORT (STAAR Surgical) flow hole.

Methods: Case report and literature review.

Results: A V4c toric ICL (STAAR Surgical) was implanted in the left eye of a 32-year-old woman. Read More

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December 2020

Unilateral Toxic Anterior Segment Syndrome Resulting in Cataract and Urrets-Zavalia Syndrome after Sequential Uneventful Implantation of a Posterior Chamber Phakic Toric Intraocular Lens at Two Different Surgical Facilities: A Series of Unfortunate Events.

Case Rep Ophthalmol Med 2020 3;2020:1216578. Epub 2020 Nov 3.

Department of Clinical Research, Black Mammoth Surgical, Medellín, Colombia.

Background: Phakic Intraocular Lens (P-IOL) implantation is a safe, easy, predictable intervention designed to manage moderate to high refractive errors. Complications are relatively uncommon and include mainly cataract and intraocular pressure spikes. Toxic Anterior Segment Syndrome (TASS) is a rather unusual sterile anterior segment inflammation after uneventful intraocular surgery, extremely rarely reported after P-IOL implantation. Read More

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November 2020

Descemet Membrane Endothelial Keratoplasty in Toxic Anterior Segment Syndrome: A Case Series.

Cornea 2021 Aug;40(8):1007-1010

Department of Ophthalmology, Meram School of Medicine, Necmettin Erbakan University, Konya, Turkey.

Purpose: To evaluate the outcomes of Descemet membrane endothelial keratoplasty (DMEK) in patients with toxic anterior segment syndrome (TASS).

Methods: Thirteen eyes of 13 patients who underwent DMEK for endothelial decompensation secondary to TASS were retrospectively reviewed. A comprehensive ocular examination including best-corrected visual acuity (BCVA), slitlamp biomicroscopy, intraocular pressure measurement, fundus evaluation, and measurement of central corneal thickness were performed in all patients at preoperatively and postoperatively. Read More

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The association between toxic anterior segment syndrome and intraocular pressure.

Graefes Arch Clin Exp Ophthalmol 2021 Feb 11;259(2):425-430. Epub 2020 Sep 11.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Purpose: To investigate the association between toxic anterior segment syndrome (TASS) and intraocular pressure (IOP).

Methods: This is a retrospective, controlled, single-site study. Patients who developed TASS following a clear corneal incision cataract surgery in Rabin Medical Center (Petah Tikva, Israel), between the years 2010-2018, were enrolled. Read More

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February 2021

Pure phaco: phacoemulsification without ophthalmic viscosurgical devices.

J Cataract Refract Surg 2020 02;46(2):174-178

From the Chandraprabha Eye Hospital, Jorhat, Assam, India.

The ophthalmic viscosurgical device (OVD) is an essential part of modern phacoemulsification surgery. Many times, OVDs are blamed for intraocular pressure spikes, toxic anterior segment syndrome, and capsular bag distension syndrome. To avoid these complications, we developed a technique in which phacoemulsification can be done without using OVDs. Read More

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February 2020

Diffuse lamellar keratitis associated with tabletop autoclave biofilms: case series and review.

J Cataract Refract Surg 2020 Mar;46(3):340-349

From the Department of Ophthalmology (Sorenson), Alta Bates Summit Medical Center, and School of Optometry (Sorenson, Tran, Evans, Lin), University of California, Berkeley, California, USA; Department of Ophthalmology (Holland), University of British Columbia, British Columbia, Vancouver, Canada; College of Pharmacy (Evans), Touro University California, Vallejo, Vision Science Graduate Group (Lin), University of California, Berkeley, California, and Moran Eye Center (Mamalis), University of Utah Medical Center, Salt Lake City, Utah, and Altos Eye Physicians (Chang), Los Altos, California, USA.

Purpose: To report a diffuse lamellar keratitis (DLK) cluster attributed to autoclave reservoir biofilm and to review the risk and prevention of DLK and toxic anterior segment syndrome (TASS) caused by such biofilms.

Setting: Refractive Surgery Center, University of California, Berkeley.

Design: Observational case-control study and review of literature. Read More

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Corneal higher-order aberrations in Stevens-Johnson syndrome and toxic epidermal necrolysis.

Ocul Surf 2019 10 17;17(4):722-728. Epub 2019 Jul 17.

Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. Electronic address:

Purpose: To characterize the topography patterns and quantify corneal higher-order aberrations (HOAs) in the chronic phase of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

Methods: This retrospective, consecutive case series included 84 eyes of 49 patients in the chronic phase of SJS/TEN. HOAs of the total cornea, and of the anterior and posterior surfaces were measured using anterior segment optical coherence tomography (AS-OCT). Read More

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October 2019