135 results match your criteria Toxic Anterior Segment Syndrome


Central Toxic Keratopathy After Contact Lens Wear and Mechanical Debridement: Clinical Characteristics, and Visual and Corneal Tomographic Outcomes.

Eye Contact Lens 2019 Jan 29. Epub 2019 Jan 29.

Sunderland Eye Infirmary (D.S.J.T., S.G.), Queen Alexandra Road, Sunderland, United Kingdom; and Academic Ophthalmology (D.S.J.T.), Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

Objectives: To highlight the clinical characteristics, and visual and corneal tomographic outcomes of central toxic keratopathy (CTK) after contact lens (CL) wear and mechanical debridement.

Methods: A retrospective observational case series with literature review.

Results: Four patients (4 eyes) were included in this study; 3 (75%) females, mean age 29. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000575DOI Listing
January 2019

Toxic Anterior Segment Syndrome: A Review.

Surv Ophthalmol 2019 Jan 28. Epub 2019 Jan 28.

Prism Eye Institute, University of Toronto, Ontario, Canada.

Toxic anterior segment syndrome (TASS) is a surgical complication characterized by a non-infectious anterior chamber inflammatory reaction having multiple etiologies. The clinical signs (prominent limbus to limbus corneal edema, anterior chamber inflammation) and symptoms (decreased visual acuity, discomfort) generally occur within the first 12-48 hours after intraocular surgery. Most patients achieve good clinical and visual outcomes when there is a prompt clinical diagnosis and adequate treatment. Read More

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http://dx.doi.org/10.1016/j.survophthal.2019.01.009DOI Listing
January 2019
1 Read

Toxic anterior segment syndrome after implantation of phakic implantable collamer lens.

Int J Ophthalmol 2019 18;12(1):175-177. Epub 2019 Jan 18.

Department of Cornea and Refractive Surgery, Conde of Valenciana Foundation Institute of Ophthalmology, Mexico City 06800, Mexico.

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http://dx.doi.org/10.18240/ijo.2019.01.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326937PMC
January 2019
2 Reads

Toxic anterior segment syndrome following phakic posterior chamber IOL: a rarity.

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Implantable collamer lenses (ICL) have gained popularity for correction of myopia where kerato-refractive procedures are not indicated as in cases of high myopic refractive errors. Toxic anterior segment syndrome (TASS) is a very uncommonly reported postoperative complication following ICL implantation. A young patient developed severe corneal oedema and anterior segment inflammation on the first day after ICL implantation. Read More

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http://dx.doi.org/10.1136/bcr-2018-225806DOI Listing
December 2018

[Complications of intracameral cefuroxime in cataract surgery].

Vestn Oftalmol 2018 ;134(5):104-110

Volga District Medical Centre, Federal Medical and Biological Agency, 2 Nizhnevolgskaya Naberegnaya, Nizhny Novgorod, Russian Federation, 603001.

Intracameral injection of cefuroxime during phacoemulsification is considered effective in preventing endophthalmitis. Its widespread usage has led to the accumulation of data on local and systemic adverse reactions. The analysis of complications of cataract surgery with cefuroxime injections described in literature has allowed identifying a few different clusters of toxic and allergic reactions to intracameral cefuroxime for the first time. Read More

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http://dx.doi.org/10.17116/oftalma2018134051104DOI Listing
January 2018
4 Reads

The evolution of toxic anterior segment syndrome.

Curr Opin Ophthalmol 2019 Jan;30(1):50-55

Department of Ophthalmology, Rabin Medical Center, Petach Tikva.

Purpose Of Review: Toxic anterior segment syndrome (TASS) is a surgical complication resulting from a noninfectious inflammatory reaction to substances used during intraocular ophthalmic surgery. Continuous reporting of new information concerning risk factors and possible causes is critical for preventing this condition.

Recent Findings: The diagnosis of TASS is clinical and its main features are well known. Read More

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http://Insights.ovid.com/crossref?an=00055735-201901000-0001
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http://dx.doi.org/10.1097/ICU.0000000000000540DOI Listing
January 2019
13 Reads

Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature.

J Med Case Rep 2018 Nov 16;12(1):349. Epub 2018 Nov 16.

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, 51 N. 39th St, Philadelphia, PA, 19104, USA.

Background: Ibrutinib is a tyrosine kinase inhibitor commonly used in patients with chronic lymphocytic leukemia. Based on the published literature, it has a very sound ophthalmologic safety profile. In the following, we describe a case of anterior chamber fibrinoid syndrome in a patient on ibrutinib for B-cell chronic lymphocytic leukemia after uncomplicated cataract extraction. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1822-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238337PMC
November 2018
7 Reads

Cluster endophthalmitis due to following intravitreal bevacizumab: outcomes of patients from North India.

Br J Ophthalmol 2018 Nov 12. Epub 2018 Nov 12.

Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Purpose: To study features, management and outcomes of cluster endophthalmitis following intravitreal bevacizumab (BCZ) injection in North India.

Methods: In this retrospective study, 28 patients (23 men) (mean age of 59.07±13 years) who received intravitreal injection of BCZ were included. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3131
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http://dx.doi.org/10.1136/bjophthalmol-2018-313131DOI Listing
November 2018
7 Reads

Toxic anterior segment syndrome-an updated review.

BMC Ophthalmol 2018 Oct 25;18(1):276. Epub 2018 Oct 25.

Department of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Background: Toxic anterior segment syndrome (TASS) can be a rare complication of anterior segment surgery. Here we reviewed the most recent advances in the understanding of TASS.

Methods: English articles related to TASS were retrieved from "PubMed" using the following keywords; "toxic anterior segment syndrome" or "TASS". Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-018-0939-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203205PMC
October 2018
10 Reads

Interface fluid syndrome secondary to endothelial failure due to toxic anterior segment syndrome after cataract surgery.

Eur J Ophthalmol 2018 Sep 11:1120672118800241. Epub 2018 Sep 11.

2 Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey.

Purpose: To present a case of previous laser in situ keratomileusis with interface fluid syndrome secondary to toxic anterior segment syndrome following cataract surgery.

Case Report: A 52-year-old woman, complaining blurred vision in her right eye for 18 months after cataract surgery, was referred to our clinic. She was diagnosed with toxic anterior segment syndrome, postoperatively, which resolved in 3 days. Read More

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http://dx.doi.org/10.1177/1120672118800241DOI Listing
September 2018
2 Reads

Descemet membrane endothelial keratoplasty in multifocal pseudophakic eyes.

Arq Bras Oftalmol 2018 Jun;81(3):183-187

Departamento de Oftalmologia, Hospital Oftalmológico de Sorocaba, Banco de Olhos de Sorocaba, Sorocaba, SP, Brazil.

Purpose: This report describes the use of Descemet membrane endothelial keratoplasty for the management of endothelial decompensation after multifocal intraocular lens implantation.

Methods: In this retrospective study, we reviewed and assessed the surgical outcomes of 9 patients (9 eyes) who underwent Descemet membrane endothelial keratoplasty after multifocal intraocular lens implantation.

Results: Corneal edema occurred due to Fuchs endothelial corneal dystrophy (n=3), pseudophakic bullous keratopathy (n=3), Descemet's membrane detachment (n=2), and toxic anterior segment syndrome (n=1). Read More

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http://dx.doi.org/10.5935/0004-2749.20180039DOI Listing
June 2018
4 Reads

Guidelines for the cleaning and sterilization of intraocular surgical instruments.

J Cataract Refract Surg 2018 Jun 13;44(6):765-773. Epub 2018 Jun 13.

From the Altos Eye Physicians (Chang), Los Altos, California, and the John A. Moran Eye Center (Mamalis), University of Utah, Salt Lake City, Utah, USA.

These Guidelines for the Cleaning and Sterilization of Intraocular Surgical Instruments were written by the Ophthalmic Instrument Cleaning and Sterilization (OICS) Task Force, comprised of representatives of the American Society of Cataract and Refractive Surgery, the American Academy of Ophthalmology, and the Outpatient Ophthalmic Surgery Society. These consensus subspecialty guidelines include evidence-based recommendations regarding issues that may be unique to the cleaning and sterilization of intraocular instrumentation. A newly published OICS Task Force study supports the safety of common short-cycle instrument processing practices for sequential same-day anterior segment surgery. Read More

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http://dx.doi.org/10.1016/j.jcrs.2018.05.001DOI Listing
June 2018
10 Reads

Limbal Stem Cell Deficiency-Demography and Underlying Causes.

Am J Ophthalmol 2018 04 31;188:99-103. Epub 2018 Jan 31.

Cornea and Anterior Segment Services, Tej Kohli Cornea Institute, L V Prasad Eye Institute, Hyderabad, India. Electronic address:

Purpose: To determine the demographic features of patients affected by limbal stem cell deficiency (LSCD), and to identify the underlying causes of LSCD.

Design: Retrospective, multicenter case series.

Setting: Two large tertiary care ophthalmology hospitals. Read More

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http://dx.doi.org/10.1016/j.ajo.2018.01.020DOI Listing
April 2018
9 Reads

Prevention and management of postoperative endophthalmitis: A case-based approach.

Indian J Ophthalmol 2017 Dec;65(12):1396-1402

Centre for Sight, New Delhi, India.

Endophthalmitis following intraocular surgery is a disastrous complication and can lead to poor visual outcomes and loss of globe integrity. It should be differentiated from toxic anterior segment syndrome (TASS) where management differs drastically. This article presents basic knowledge about postoperative endophthalmitis and describes nine different real-world scenarios ranging from TASS to milder forms of endophthalmitis responding to intravitreal antibiotics alone and more complicated forms associated with corneal involvement, fungal endophthalmitis and cases requiring intraocular lens removal, radical vitrectomy with hyaloid peeling, base dissection, and silicone oil. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1058_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742968PMC
December 2017
3 Reads

Corneal edema after phacoemulsification.

Indian J Ophthalmol 2017 Dec;65(12):1381-1389

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Phacoemulsification is the most commonly performed cataract surgery in this era. With all the recent advances in investigations and management of cataract through phacoemulsification, most of the patients are able to achieve excellent visual outcome. Corneal edema after phacoemulsification in the immediate postoperative period often leads to patient dissatisfaction and worsening of outcome. Read More

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http://dx.doi.org/10.4103/ijo.IJO_871_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742966PMC
December 2017
4 Reads

Incidence of endophthalmitis and the perioperative practices of cataract surgery in Japan: Japanese Prospective Multicenter Study for Postoperative Endophthalmitis after Cataract Surgery.

Jpn J Ophthalmol 2018 Jan 1;62(1):24-30. Epub 2017 Nov 1.

Ehime University, Ehime, Japan.

Purpose: To prospectively survey the incidence of endophthalmitis following cataract surgery and investigate the current perioperative practices in Japan.

Methods: Patients who underwent cataract surgery from January 2012 to December 2013 were included. Information on perioperative practices were recorded prospectively. Read More

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http://dx.doi.org/10.1007/s10384-017-0545-6DOI Listing
January 2018
19 Reads

Generic trypan blue as possible cause of a cluster of toxic anterior segment syndrome cases after uneventful cataract surgery.

J Cataract Refract Surg 2017 Jun;43(6):848-852

From the 2nd Department of Ophthalmology, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Five of 16 patients having uneventful cataract surgery over 2 consecutive days presented on the first postoperative day with painless, unexpected blurry vision; marked limbus-to-limbus corneal edema; and severe anterior chamber inflammation with hypopyon and fibrin formation. Review of the records showed the 5 patients had received an intracameral injection of generic trypan blue solution 0.06% to facilitate the capsulorhexis. Read More

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http://dx.doi.org/10.1016/j.jcrs.2017.06.002DOI Listing
June 2017
4 Reads

Toxic Anterior Segment Syndrome Outbreak after Cataract Surgery Triggered by Viscoelastic Substance.

Middle East Afr J Ophthalmol 2017 Jan-Mar;24(1):43-47

Department of Ophthalmology, Ulucanlar Eye Research and Training Hospital, Ankara, Turkey.

Purpose: The purpose of this study is to present toxic anterior segment syndrome (TASS) outbreak at our clinic and discuss possible causes of TASS.

Materials And Methods: Thirty-four eyes of 34 patients developed TASS in a consecutive 2 weeks period were included in this study. Both anterior segment and fundus examinations were performed before and after uncomplicated cataract surgery. Read More

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http://dx.doi.org/10.4103/meajo.MEAJO_226_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433127PMC
June 2017
13 Reads

Risks of Cefuroxime Prophylaxis for Postcataract Endophthalmitis.

Middle East Afr J Ophthalmol 2017 Jan-Mar;24(1):24-29

Research Department, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saud Arabia.

Background: Endophthalmitis after cataract surgery is a rare but vision-threatening complication. Intracameral cefuroxime (ICC) has been reported to be effective at reducing the risk, but concerns regarding the risks associated with this intervention remain.

Methods: Systematic review and synthesis of the literature on ICC, with a focus on the risks of therapy. Read More

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http://dx.doi.org/10.4103/meajo.MEAJO_255_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433125PMC
June 2017
10 Reads

Failure Modes and Effects Analysis of bilateral same-day cataract surgery.

J Cataract Refract Surg 2017 Mar;43(3):318-323

From Kaiser Permanente (Shorstein, Lucido), Walnut Creek, Kaiser Permanente (Carolan), San Rafael, Division of Research (Liu, Herrinton), Kaiser Permanente, Oakland, and the California Pacific Medical Center (Slean), San Francisco, California, USA.

Purpose: To systematically analyze potential process failures related to bilateral same-day cataract surgery toward the goal of improving patient safety.

Setting: Twenty-one Kaiser Permanente surgery centers, Northern California, USA.

Design: Retrospective cohort study. Read More

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http://dx.doi.org/10.1016/j.jcrs.2016.12.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419427PMC
March 2017
5 Reads

Toxic anterior segment syndrome in a tertiary Australian healthcare institution.

Clin Exp Ophthalmol 2017 09 9;45(7):750-752. Epub 2017 May 9.

Department of Ophthalmology, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/ceo.12951DOI Listing
September 2017
9 Reads

The role of patient's systemic characteristics and plateletcrit in developing toxic anterior segment syndrome after uneventful phaco surgery: A case-control study.

Int Ophthalmol 2018 Feb 27;38(1):43-52. Epub 2017 Jan 27.

Department of Ophthalmology, Medical Faculty, Bulent Ecevit University, Zonguldak, Turkey.

Purpose: To compare the systemic and ocular characteristics and laboratory findings of patients developing toxic anterior segment syndrome (TASS) after uneventful phaco surgery with unaffected subjects undergoing the same surgery in the same session.

Design: A retrospective case-control study.

Methods: The study group consisted of 26 eyes of 26 patients who underwent uneventful phaco surgery and who went on to develop TASS, while the control group included 39 subjects who had routine phaco surgery in the same session by the same surgeon. Read More

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http://dx.doi.org/10.1007/s10792-016-0418-xDOI Listing
February 2018
9 Reads

Toxic Anterior Segment Syndrome: Inadvertent Administration of Intracameral Lidocaine 1% and Phenylephrine 2.5% Preserved With 10% Benzalkonium Chloride During Cataract Surgery.

Cornea 2017 May;36(5):621-624

University of Miami, Bascom Palmer Eye Institute, Miami, Florida.

Purpose: To report 3 patients with corneal decompensation and anterior uveitis within 24 hours of cataract surgery from a single ambulatory surgery center using intracameral lidocaine HCl 1% and phenylephrine 2.5% inadvertently preserved with 10% benzalkonium chloride.

Methods: This case series describes 3 patients who underwent traditional cataract extraction with a significant decrease in visual acuity in the immediate postoperative period resulting in secondary surgical intervention for corneal decompensation in 2 patients. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001145DOI Listing
May 2017
5 Reads

Outbreak of Subacute-Onset Toxic Anterior Segment Syndrome Associated with Single-Piece Acrylic Intraocular Lenses.

Ophthalmology 2017 04 19;124(4):519-523. Epub 2017 Jan 19.

Department of Ophthalmology, Ehime University, Graduate School of Medicine, Ehime, Japan.

Purpose: To report the results of a clinical investigation after an outbreak of subacute-onset toxic anterior segment syndrome (TASS) after implantation of single-piece acrylic intraocular lenses (IOLs), which then were recalled voluntarily from the market.

Design: Retrospective, multicenter, observational case series.

Participants: Cases reported to the manufacturer from January 2015 through March 2016 of unusual ocular inflammation after cataract surgery using AcrySof ReSTOR, ReSTOR toric, or AcrySof IQ toric SN6AT6-9 IOLs (Alcon Laboratories, Inc. Read More

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http://dx.doi.org/10.1016/j.ophtha.2016.12.010DOI Listing
April 2017
7 Reads

Toxic anterior segment syndrome following deep anterior lamellar keratoplasty.

Arq Bras Oftalmol 2016 Sep-Oct;79(5):330-332

Department of Ophthalmology, Istanbul Medeniyet University School of Medicine, Istanbul, Turkey.

We present the case of a 31-year-old patient with toxic anterior segment syndrome (TASS) that developed after undergoing deep anterior lamellar keratoplasty (DALK). She had keratoconus, and despite wearing hard contact lenses for many years in the left eye, her vision had deteriorated; therefore, DALK was performed on this eye. The preoperative visual acuity (VA) was finger counting at 3 m. Read More

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http://dx.doi.org/10.5935/0004-2749.20160094DOI Listing
July 2017
33 Reads
1 Citation
0.440 Impact Factor

Toxic anterior segment syndrome caused by autoclave reservoir wall biofilms and their residual toxins.

J Cataract Refract Surg 2016 11;42(11):1602-1614

From the Department of Ophthalmology (A.L. Sorenson), California Pacific Medical Center, San Francisco, the School of Optometry (A.L. Sorenson, Evans), University of California, Berkeley, the Alta Bates Summit Medical Center (R.L. Sorenson), Berkeley, and the College of Pharmacy (Evans), Touro University California, Vallejo, California, USA.

Purpose: To identify etiology of toxic anterior segment syndrome (TASS) after uneventful phacoemulsification.

Setting: EyeMD Laser and Surgery Center, Oakland, California.

Design: Retrospective case series. Read More

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http://dx.doi.org/10.1016/j.jcrs.2016.08.030DOI Listing
November 2016
10 Reads

Retropupillary fixation of iris-claw lens in visual rehabilitation of aphakic eyes.

Indian J Ophthalmol 2016 Oct;64(10):743-746

Department of Vitreoretina, Sankara Eye Hospital, Guntur, Andhra Pradesh, India.

Context: Surgical outcome of retropupillary fixation of iris claw lens.

Aims: To evaluate the various indications, intra and post-operative complications, and visual outcome of retropupillary fixation of iris claw lens in aphakic eyes.

Settings And Design: The study design is a retrospective study at a tertiary eye care center. Read More

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http://dx.doi.org/10.4103/0301-4738.195012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168915PMC
October 2016
8 Reads

Outcomes of Descemet Stripping Automated Endothelial Keratoplasty in Toxic Anterior Segment Syndrome After Phacoemulsification.

Cornea 2017 Jan;36(1):17-20

Cornea, Cataract and Refractive Surgery Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To evaluate the visual and anatomical outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with toxic anterior segment syndrome (TASS).

Methods: Fourteen eyes of 14 patients who underwent clear corneal DSAEK for endothelial decompensation secondary to TASS after phacoemulsification were included in this prospective study. Intraoperative surgical difficulties were noted. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001067DOI Listing
January 2017
8 Reads

Rapid detection of bacterial endotoxins in ophthalmic viscosurgical device materials by direct analysis in real time mass spectrometry.

Anal Chim Acta 2016 Nov 29;943:98-105. Epub 2016 Sep 29.

Division of Biology, Chemistry, and Materials Science, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, 20993, United States. Electronic address:

Bacterial endotoxins are lipopolysaccharides bound to the bacterial cell wall and released when bacteria rupture or disintegrate. Possible contamination of endotoxin in ophthalmic devices can cause a painful eye inflammation or result in toxic anterior segment syndrome after cataract surgery. Measurement of bacterial endotoxin in medical device materials is difficult since endotoxin binds with polymer matrix and some of the materials are very viscous and non-water soluble, where traditional enzyme-based Limulus amebocyte lysate (LAL) assay cannot be applied. Read More

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http://dx.doi.org/10.1016/j.aca.2016.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500980PMC
November 2016
7 Reads

Endophthalmitis or toxic anterior segment syndrome?

Clin Exp Optom 2017 Jan 12;100(1):94-95. Epub 2016 Aug 12.

Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/cxo.12426DOI Listing
January 2017
7 Reads

Impact of Indocyanine Green Concentration, Exposure Time, and Degree of Dissolution in Creating Toxic Anterior Segment Syndrome: Evaluation in a Rabbit Model.

J Ophthalmol 2016 12;2016:3827050. Epub 2016 Jul 12.

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Republic of Korea.

Purpose. To investigate the role of indocyanine green (ICG) dye as a causative material of toxic anterior segment syndrome (TASS) in an experimental rabbit model. Method. Read More

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http://dx.doi.org/10.1155/2016/3827050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960341PMC
August 2016
17 Reads

[Toxic anterior segment syndrome following cataract surgery].

Ophthalmologe 2016 Aug;113(8):708-11

Augenklinik der Medizinischen Fakultät "Carl Gustav Carus", Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland.

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http://dx.doi.org/10.1007/s00347-015-0179-3DOI Listing
August 2016
21 Reads

The Safety and Efficacy of Routine Administration of Intracameral Vancomycin during Cataract Surgery.

J Ophthalmol 2015 4;2015:813697. Epub 2015 Nov 4.

Panhandle Eye Group, 7400 Fleming Avenue, Amarillo, TX 79106, USA ; Texas Tech University Health Sciences Center, 1400 S. Coulter, Amarillo, TX 79106, USA ; Southwest Retina Specialists, 7411 Wallace Boulevard, Amarillo, TX 79106, USA.

Purpose. To evaluate the safety and efficacy of intracameral vancomycin during cataract surgery using a standardized dosage and delivery technique. Methods. Read More

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http://dx.doi.org/10.1155/2015/813697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649092PMC
November 2015
7 Reads

Toxic anterior segment syndrome and intracameral injection of cefuroxime axetil.

Clin Ophthalmol 2015 3;9:1865-7. Epub 2015 Oct 3.

Retina and Vitreous Section, Ophthalmology Service, Hospital Universitario de Canarias, Spain.

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http://dx.doi.org/10.2147/OPTH.S91943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599142PMC
October 2015
2 Reads

Viscoelastic substance in prefilled syringe as an etiology of Toxic Anterior Segment Syndrome.

Cutan Ocul Toxicol 2016 Sep 11;35(3):237-41. Epub 2015 Sep 11.

a Department of Ophthalmology , Taif University , Taif , Saudi Arabia.

Context: Toxic Anterior Segment Syndrome (TASS) is an acute postoperative inflammatory reaction in which a noninfectious substance enters the anterior segment and induces toxic damage to the intraocular tissues.

Objective: To present etiologic investigation of two consecutive clusters of TASS. TASS outbreak and investigation: This paper presents two consecutive clusters of TASS in 15 of the 24 uneventful surgeries and the investigation carried out to find the etiology. Read More

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http://www.tandfonline.com/doi/full/10.3109/15569527.2015.10
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http://dx.doi.org/10.3109/15569527.2015.1082579DOI Listing
September 2016
14 Reads

Evaluation of the retinal, choroidal, and nerve fiber layer thickness changes in patients with toxic anterior segment syndrome.

Graefes Arch Clin Exp Ophthalmol 2016 Mar 14;254(3):583-4. Epub 2015 Aug 14.

Department of Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1007/s00417-015-3109-9DOI Listing
March 2016
4 Reads

Toxic anterior segment syndrome - A sequel of uneventful cataract surgery.

Med J Armed Forces India 2015 Jul 3;71(Suppl 1):S205-7. Epub 2014 Apr 3.

Associate Professor, Dept of Ophthalmology, Armed Forces Medical College, Pune 411040, India.

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http://dx.doi.org/10.1016/j.mjafi.2014.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529552PMC
July 2015
3 Reads

Response to letter regarding the publication "Evaluation of the retinal, choroidal and nerve fiber layer thickness changes in patients with toxic anterior segment syndrome".

Graefes Arch Clin Exp Ophthalmol 2016 Mar 5;254(3):585-6. Epub 2015 Aug 5.

Department of Ophthalmology, Tel Aviv Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv, 6423906, Israel.

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http://link.springer.com/10.1007/s00417-015-3112-1
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http://dx.doi.org/10.1007/s00417-015-3112-1DOI Listing
March 2016
1 Read

Toxic anterior segment syndrome after uncomplicated cataract surgery possibly associated with intracamaral use of cefuroxime.

Clin Ophthalmol 2015 17;9:493-7. Epub 2015 Mar 17.

Sakarya University Education and Research Hospital, Sakarya, Turkey.

Purpose: To report toxic anterior segment syndrome (TASS) after cataract surgery possibly associated with intracameral use of cefuroxime.

Methods: We conducted a retrospective chart review and analysis on the pre- and postoperative conditions of the subjects who had developed TASS.

Results: The patient group consisted of 17 patients. Read More

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http://www.dovepress.com/toxic-anterior-segment-syndrome-aft
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http://dx.doi.org/10.2147/OPTH.S74249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370909PMC
April 2015
6 Reads

Late-onset toxic anterior segment syndrome.

J Cataract Refract Surg 2015 Mar 14;41(3):666-9. Epub 2015 Feb 14.

From the Department of Ophthalmology (G. Miyake, Zako, Iwaki), Aichi Medical University, Aichi, the Shohzankai Medical Foundation (G. Miyake, Ota, K. Miyake), Miyake Eye Hospital, Nagoya, and Hoya Corporation Medical Division (Shibuya), Tokyo, Japan.

Unlabelled: We describe 6 cases that developed intraocular inflammation between 42 days and 137 days after implantation of an acrylic foldable intraocular lens (IOL) (ISert model 251) and failed to respond to antibiotic treatment. One eye required a vitrectomy and IOL removal, 2 eyes required irrigation of the capsule, and 5 eyes required systemic administration of steroids. The healing process took 30 to 108 days after onset. Read More

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http://search.proquest.com/openview/1eb60603032f8e7d72dfaf76
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http://linkinghub.elsevier.com/retrieve/pii/S088633501500091
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http://dx.doi.org/10.1016/j.jcrs.2015.01.002DOI Listing
March 2015
3 Reads

IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement.

J Allergy Clin Immunol 2015 Jun 8;135(6):1538-45.e17. Epub 2015 Feb 8.

Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan. Electronic address:

Background: Stevens-Johnson syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes, including the ocular surface, oral cavity, and genitals. These reactions are very rare but are often associated with inciting drugs, infectious agents, or both.

Objective: We sought to identify susceptibility loci for cold medicine-related SJS/TEN (CM-SJS/TEN) with severe mucosal involvement (SMI). Read More

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http://dx.doi.org/10.1016/j.jaci.2014.12.1916DOI Listing
June 2015
20 Reads

Outbreak of late-onset toxic anterior segment syndrome after implantation of one-piece intraocular lenses.

Am J Ophthalmol 2015 May 28;159(5):934-9.e2. Epub 2015 Jan 28.

Miyata Eye Hospital, Miyazaki, Japan.

Purpose: To describe clinical findings associated with an outbreak of toxic anterior segment syndrome (TASS) after implantation of 1-piece intraocular lenses (IOLs; HOYA iSert(®) 251 and 255; HOYA Co Ltd, Tokyo, Japan) contaminated with aluminum.

Design: Multicenter observational retrospective case series.

Methods: Cases developing TASS after IOL implantation from November 2011 to February 2013 were reported to the HOYA IOL-Related Endophthalmitis Investigation Committee. Read More

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http://dx.doi.org/10.1016/j.ajo.2015.01.023DOI Listing
May 2015
17 Reads

Toxic Anterior Segment Syndrome following Phacoemulsification Secondary to Overdose of Intracameral Gentamicin.

Case Rep Med 2014 10;2014:143564. Epub 2014 Dec 10.

Kafkas University, 36100 Kars, Turkey.

Objective. To report a case of toxic anterior segment syndrome (TASS) that was caused by inadvertent anterior chamber and cornea stromal injection with high dose gentamicin following cataract surgery. Methods. Read More

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http://www.hindawi.com/journals/crim/2014/143564/
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http://dx.doi.org/10.1155/2014/143564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276686PMC
January 2015
13 Reads

Evaluation of the retinal, choroidal, and nerve fiber layer thickness changes in patients with toxic anterior segment syndrome.

Graefes Arch Clin Exp Ophthalmol 2015 Mar 3;253(3):467-75. Epub 2014 Dec 3.

Department of Ophthalmology, Tel Aviv Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv, 6423906, Israel,

Purpose: To evaluate changes in choroidal, retinal, and nerve fiber layer (NFL) thickness following toxic anterior segment syndrome (TASS).

Methods: Macular and peripapillary choroidal thickness was measured using enhanced depth imaging (EDI) optical coherence tomography (OCT) on the day of the diagnosis and on three follow-up exams (months 1 to 4). A similar OCT analysis of central retinal and NFL thickness was performed. Read More

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http://dx.doi.org/10.1007/s00417-014-2880-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345267PMC
March 2015
4 Reads

Intracameral antibiotics: Safety, efficacy, and preparation.

J Cataract Refract Surg 2014 Dec 24;40(12):2134-42. Epub 2014 Nov 24.

From the University of Toronto, Toronto, Canada (Braga-Mele); University of California, San Francisco, San Francisco, CA (Chang); Tufts University School of Medicine, Boston, MA (Henderson); Moran Eye Centre, University of Utah, Salt Lake City, UT (Mamalis); Northwest Eye Surgeons, Seattle, WA (Talley-Rostov); Raghudeep Eye Clinic, Ahmedabad, India (Vasavada).

Unlabelled: Endophthalmitis is a rare but potentially devastating complication of cataract surgery. This article presents an overview of endophthalmitis prophylaxis and the use of intracameral antibiotics. It highlights available intracameral antibiotics with respect to pharmacology, spectrum of activity, dosage and preparation, safety, and efficacy profiles, as well as toxic anterior segment syndrome risks to better define the potential use of these medications in the prevention of endophthalmitis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08863350140130
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http://dx.doi.org/10.1016/j.jcrs.2014.10.010DOI Listing
December 2014
6 Reads

Toxic anterior-segment syndrome (TASS).

Clin Ophthalmol 2014 9;8:2065-9. Epub 2014 Oct 9.

Ophthalmology Clinics, Beyhekim State Hospital, Konya, Turkey.

Purpose: To evaluate the clinical findings and courses of five patients who developed toxic anterior-segment syndrome (TASS) after cataract surgery and investigate the cause.

Materials And Methods: In May 2010, on the same day, ten patients were operated on by the same surgeon. Five of these patients developed TASS postoperatively. Read More

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http://dx.doi.org/10.2147/OPTH.S71541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199838PMC
October 2014
18 Reads

Mild toxic anterior segment syndrome mimicking delayed onset toxic anterior segment syndrome after cataract surgery.

Authors:
Su-Na Lee

Indian J Ophthalmol 2014 Aug;62(8):890-2

Department of Ophthalmology, Eulji University Hospital, Daejeon, South Korea.

Toxic anterior segment syndrome (TASS) is an acute sterile postoperative anterior segment inflammation that may occur after anterior segment surgery. I report herein a case that developed mild TASS in one eye after bilateral uneventful cataract surgery, which was masked during early postoperative period under steroid eye drop and mimicking delayed onset TASS after switching to weaker steroid eye drop. Read More

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http://dx.doi.org/10.4103/0301-4738.141067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185172PMC
August 2014
5 Reads

[Same day postoperative examination after cataract surgery under local anesthesia--huge economic impact without increased risk].

Harefuah 2014 Jul;153(7):385-8, 434

Introduction: Cataract surgery is one of the most common surgeries in medicine. Re-evaluating the regimen for followup might save thousands of visits to the clinic and many working days every year.

Purpose: To check the safety of same day postoperative follow-up as a substitute for the common practice in Israel of examination on the next day. Read More

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July 2014
4 Reads