1,942,289 results match your criteria Total Joint Replacement Rehabilitation


Hypercortisolism in Newly Diagnosed Type 2 Diabetes: A Prospective Study of 384 Newly Diagnosed Patients.

Horm Metab Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

Cross-sectional studies in small and selected populations report a high prevalence of hypercortisolism in patients with type 2 diabetes (T2D), which could have therapeutic implications, if confirmed. We therefore estimated the prevalence of hypercortisolism in a large and unselected cohort of recently diagnosed T2D patients. Consecutive patients with recently diagnosed T2D first underwent an overnight dexamethasone (1 mg) suppression test (OD). Read More

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December 2018
1 Read

Impact of Hybrid Therapy Comprising Peritoneal Dialysis and Hemodialysis on Acute Cardiovascular Events.

Blood Purif 2018 Dec 6:1-7. Epub 2018 Dec 6.

Background: The impact of hybrid therapy comprising peritoneal dialysis (PD) and hemodialysis on cardiovascular events in PD patients remains unclear.

Objective: We aimed to evaluate the effect of hybrid therapy on cardiovascular events.

Methods: A total of 93 PD patients undergoing hybrid therapy for ≥3 years were divided into 2 groups according to left ventricular ejection fraction (LVEF): lower ejection fraction (LEF [n = 29], LVEF < 60%) and normal ejection fraction (NEF [n = 64], LVEF ≥60%). Read More

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December 2018
2 Reads

Developing a Process for Returning Medically Actionable Genomic Variants to Latino Patients in a Federally Qualified Health Center.

Public Health Genomics 2018 Dec 6:1-8. Epub 2018 Dec 6.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

Aim: To develop a process for returning medically actionable genomic variants to Latino patients receiving care in a Federally Qualified Health Center.

Methods: Prior to recruitment, researchers met with primary care providers to (1) orient clinicians to the project, (2) establish a process for returning actionable and nonactionable results to participants and providers through the electronic health record, and (3) develop a process for offering clinical decision support for follow-up education and care. A Community Advisory Board was engaged to provide input on recruitment strategies and materials for conveying results to participants. Read More

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December 2018
2 Reads

β-Elemene Inhibits Human Sperm Function by Affecting Sperm Vitality and Intracellular Calcium.

Cell Physiol Biochem 2018 Dec 6;51(5):2019-2029. Epub 2018 Dec 6.

State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou,

Background/aims: β-Elemene is a bioactive sesquiterpene compound that exhibits a potent anti-tumor effect and is used in various clinical applications. However, little is known about its effect on the male reproductive system. The objective of this study was to investigate the in vitro actions of β-elemene on human sperm function and elucidate the underlying mechanism. Read More

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December 2018
3 Reads

The legacy of colonial fire management policies on traditional livelihoods and ecological sustainability in savannas: Impacts, consequences, new directions.

J Environ Manage 2018 Dec 3;232:600-606. Epub 2018 Dec 3.

Darwin Centre for Bushfire Research, Charles Darwin University, Darwin, Australia. Electronic address:

Land occupation and management systems have defined fire regimes and landscapes for millennia. The savanna biome is responsible for 86% of all fire events, contributes to 10% of the total carbon emissions annually and is home to 10% of the human population. European colonization has been associated with the implementation of fire suppression policies in many tropical savanna regions, markedly disrupting traditional fire management practices and transforming ecosystems. Read More

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December 2018
2 Reads

Online behavior of people visiting a scientific website on epilepsy.

Epilepsy Behav 2018 Dec 3;90:79-83. Epub 2018 Dec 3.

'Sapienza' University of Rome, Human Neuroscience Department, Rome, Italy.

We investigated the online behavior of Internet users consulting the website of the Italian Chapter of the International League Against Epilepsy (Lega Italiana Contro l'Epilessia [LICE]). We obtained the visualization statistics of the LICE website using AWStats (https://awstats.sourceforge. Read More

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December 2018
1 Read

Patient readiness for hospital discharge and its relationship to discharge preparation and structural factors: A cross-sectional study.

Int J Nurs Stud 2018 Nov 19;90:13-20. Epub 2018 Nov 19.

Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056 Basel, Switzerland; Inselspital Bern University Hospital, Nursing Research Unit, 3010 Bern, Switzerland.

Background: Nursing discharge preparation is vital to successful hospital-to-home transitions. However, despite a wealth of evidence on its effectiveness, little is known of the structure- and process-related factors that facilitate or impede its use in clinical practice. Specifically, the associations between unit size and type, leadership support, skill mix, staffing, nurse and patient characteristics, discharge teaching and patient readiness for discharge have rarely been studied. Read More

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November 2018
6 Reads

Microbubble aeration enhances performance of vacuum membrane distillation desalination by alleviating membrane scaling.

Water Res 2018 Nov 20;149:588-595. Epub 2018 Nov 20.

School of Environmental Science and Engineering, State Key Laboratory of Control and Resource Reuse, Tongji University, 1239, Siping Road, Shanghai, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China. Electronic address:

Membrane fouling, especially inorganic fouling due to salt crystal formation and deposition on the membrane surface, is still a major technical issue in membrane distillation (MD) applications. In this study, microbubble aeration (MBA) was included in a laboratory-scale vacuum membrane distillation (VMD) rig and its effect on a desalination process was examined. Without MBA, serious membrane scaling occurred during desalination of simulated high-salinity sea water (100 g. Read More

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November 2018
2 Reads

Incidence of future arrests in adults involved in the criminal justice system with opioid use disorder receiving extended release naltrexone compared to treatment as usual.

Drug Alcohol Depend 2018 Dec 3;194:482-486. Epub 2018 Dec 3.

Department of Academic Affairs, Baystate Medical Center, 3601 Main St., Springfield, MA 01199, United States. Electronic address:

Background: Criminal justice involved (CJS) populations with opioid use disorder (OUD) have high rates of relapse, future arrests, and death upon release. While medication for OUD (MOUD) reduces opioid relapse, concerns regarding diversion and stigma limit treatment in CJS populations. Extended release naltrexone (XR-NTX), as an opioid antagonist, may be more acceptable to CJS administrators. Read More

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December 2018
1 Read

The prevalence and prognostic value of myelin oligodendrocyte glycoprotein antibody in adult optic neuritis.

J Neurol Sci 2018 Nov 28;396:225-231. Epub 2018 Nov 28.

Department of Ophthalmology, Military General Hospital of Beijing PLA, Beijing, China. Electronic address:

Background And Objective: Adult demyelinating optic neuritis (ON) with positive myelin-oligodendrocyte glycoprotein antibody (MOG-Ab) has distinct clinical features. This study aimed to investigate the point prevalence, relationship with steroid dependency and prognosis value of MOG-Ab in adult ON.

Methods: Clinical data analysis was undertaken in adults with ON admitted between December 2014 and January 2016. Read More

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November 2018
1 Read

Does exclusive breastfeeding relate to the longer duration of breastfeeding? A prospective cohort study.

Midwifery 2018 Nov 19;69:163-171. Epub 2018 Nov 19.

Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA. Electronic address:

Objectives: Suboptimal breastfeeding contributes to morbidity and mortality in children. Studies in high-income countries (HICs) show that exclusive-breastfeeding (EBF) is associated with longer breastfeeding duration. The aim of this study was to determine whether maternal reports of EBF at six months are associated with longer duration of breastfeeding during the first two years of life in a low and middle-income country (LMIC) setting, and to identify determinants of breastfeeding duration. Read More

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November 2018

Effects of ofloxacin on nitrogen removal and microbial community structure in constructed wetland.

Sci Total Environ 2018 Nov 27;656:503-511. Epub 2018 Nov 27.

Department of Civil and Environmental Engineering, National University of Singapore, 1 Engineering Drive 2, E1A 07-03, Singapore117576, Singapore.

Constructed wetlands (CWs) have emerged as a promising technology for the purification of micro-polluted water. However, their nitrogen removal performance can be significantly degraded by design, operational, and environmental factors. The present study investigates the effects of ofloxacin (OFL: 0. Read More

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November 2018
1 Read

Viability-based quantification of antibiotic resistance genes and human fecal markers in wastewater effluent and receiving waters.

Sci Total Environ 2018 Nov 22;656:495-502. Epub 2018 Nov 22.

Department of Civil and Environmental Engineering, Rutgers, The State University of New Jersey, 500 Bartholomew Dr, Piscataway, NJ 08854, United States. Electronic address:

Antibiotic resistance is a public health issue with links to environmental sources of antibiotic resistance genes (ARGs). ARGs from nonviable sources may pose a hazard given the potential for transformation whereas ARGs in viable sources may proliferate during host growth or conjugation. In this study, ARGs in the effluent from three municipal wastewater treatment plants (WWTPs) and the receiving surface waters were investigated using a viability-based qPCR technique (vPCR) with propidium monoazide (PMA). Read More

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November 2018
1 Read

An environmental flow determination method for integrating multiple-scale ecohydrological and complex ecosystem processes in estuaries.

Sci Total Environ 2018 Nov 22;656:482-494. Epub 2018 Nov 22.

Nelson Mandela University, PO Box 77000, Port Elizabeth 6031, South Africa. Electronic address:

This paper presents an environmental flow methodology that was developed to accommodate shallow, highly dynamic micro-tidal estuaries found along the wave-dominated coast of South Arica. This method differs to most other approaches that primarily focus on larger permanently open systems having unrestricted inlets. Following an adaptive, design science research approach, the 7-step method adopted both ecohydrological and ecosystem-based concepts, encapsulating key hydrologicalhydrodynamic-biogeochemical processes, as well as biotic responses. Read More

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November 2018
2 Reads

Temporal fluctuations in young-of-the-year yellow perch mercury bioaccumulation in lakes of northeastern Minnesota.

Sci Total Environ 2018 Nov 22;656:475-481. Epub 2018 Nov 22.

USDA Forest Service, Superior National Forest, 8901 Grand Ave Place, Duluth, MN 55808, USA. Electronic address:

Identifying what determines fish mercury (Hg) bioaccumulation remains a key scientific challenge. While there has been substantial research on spatial variation in fish Hg bioaccumulation, the factors that influence temporal fluctuations in fish Hg have received less attention to date. In this study, we built upon a growing body of research investigating young-of-the-year (YOY) yellow perch Hg bioaccumulation and investigated annual fluctuations in YOY yellow perch Hg in six lakes in northeastern Minnesota over eight years. Read More

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November 2018
2 Reads

Methane emissions from anaerobic sludge digesters in Mexico: On-site determination vs. IPCC Tier 1 method.

Sci Total Environ 2018 Nov 26;656:468-474. Epub 2018 Nov 26.

Instituto de Ingeniería, Universidad Nacional Autónoma de México, Av. Universidad 3000, 04510 México D.F., México. Electronic address:

Wastewater treatment is an important source of methane (CH) emissions. In most large-size aerobic treatment plants, the excess sludge is digested in anaerobic reactors (AD), with the concomitant CH emissions. The guidelines of the Intergovernmental Panel on Climate Change (IPCC) have been adopted worldwide for quantifying the national emission inventories, which include wastewater treatment plants (WWTP) as a key category. Read More

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November 2018
1 Read

Quantifying streamflow response to climate variability, wastewater inflow, and sprawling urbanization in a heavily modified river basin.

Sci Total Environ 2018 Nov 23;656:458-467. Epub 2018 Nov 23.

Department of Hydrology, Faculty of Geography and Regional Studies, University of Warsaw, Krakowskie Przedmieście 30, 00-927 Warsaw, Poland. Electronic address:

Considering the growing recognition that human activity and climate variability are critical stressors influencing river regimes, there is an urgent need to identify the contribution of these fundamental factors. Here we examine the runoff changes of a wastewater-effluent dominated river flowing in a heavily modified urban environment. The study concerns the Utrata River basin (727 km), central Poland, a challenging human-natural system for investigating changes in hydrological processes. Read More

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November 2018

On-line measurement of fluorescent aerosols near an industrial zone in the Yangtze River Delta region using a wideband integrated bioaerosol spectrometer.

Sci Total Environ 2018 Nov 26;656:447-457. Epub 2018 Nov 26.

Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China. Electronic address:

In this work, we present on-line fluorescent aerosol measurements by the wideband integrated bioaerosol spectrometer (WIBS-4A) near an industrial zone in Nanjing, a megacity in the Yangtze-River-Delta (YRD) region. The fieldwork was conducted from April 1 to May 8, 2014. A TSI. Read More

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November 2018
1 Read

The impact of dam flushing event on dissolved trace elements concentrations: Coupling integrative passive sampling and discrete monitoring.

Sci Total Environ 2018 Nov 22;656:433-446. Epub 2018 Nov 22.

Irstea, UR RiverLy, centre de Lyon-Villeurbanne, 5 rue de la Doua, CS 20244, F-69625, Villeurbanne Cedex, France.

Sediments accumulation in reservoirs induces water storage capacities reduction and flood risks increases rendering dam flushing or dredging events compulsory for security reasons. Short transient events like dam flushing monitoring is still a great challenge because the suspended sediments and contaminants concentrations increases could occur over only few hours/days and cover tens of kilometres. Since 1942, 21 dam flushing events have been performed on the Upper Rhône River (from Lake Geneva in Switzerland to Lyon in France) in order to evacuate accumulated sediments behind the Verbois dam (Switzerland). Read More

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November 2018

Neuromuscular activation of the knee and hip extensor muscles during high-intensity interval and moderate-intensity constant cycling.

J Electromyogr Kinesiol 2018 Nov 28;44:64-69. Epub 2018 Nov 28.

Research Center of Health, Physical Fitness & Sports, Nagoya University, Nagoya, Japan; Graduate School of Education and Human Development, Nagoya University, Nagoya, Japan.

We aimed to test the hypothesis that the magnitude of differences in muscle activation of the knee and hip extensor muscles between high-intensity interval exercise (HIE) and moderate-intensity constant exercise (CE) would be greater for the gluteus maximus than for the quadriceps femoris muscle. Participants were 11 male middle- or long-distance runners. The HIE (4 sets, 4-min induration, performed at 80-85%VO and followed by a 3-min period of cycling at < 30%VO) and CE (28-min, performed at or near 60%VO) were completed on different days, with the total exercise duration and work being identical for both protocols. Read More

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November 2018
2 Reads

Developing crash prediction models using parametric and nonparametric approaches for rural mountainous freeways: A case study on Wyoming Interstate 80.

Accid Anal Prev 2018 Dec 3;123:176-189. Epub 2018 Dec 3.

Department of Mathematics and Statistics, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA. Electronic address:

Interstate 80 in Wyoming is one of the busiest freight corridors that is characterized with harsh winter conditions and challenging mountainous roadway sections. The fatality rates in Wyoming are always typically higher than the national level. The 402-mile I-80 corridor in Wyoming was selected by the USDOT FHWA for piloting connected vehicle technology to improve the safety and mobility of heavy trucks. Read More

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December 2018

Metabolic syndrome, depression and anhedonia among young adults.

Psychiatry Res 2018 Aug 7;271:306-310. Epub 2018 Aug 7.

Translational Science on Brain Disorders, Department of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, Brazil; Department of Epidemiology, Federal University of Pelotas, Pelotas, RS, Brazil.

The aim of this study was to assess the association between anhedonia and metabolic syndrome (MetS) in a well-characterized community sample of individuals with a current depressive episode. This is a cross-sectional study with young adults aged 24-30 years old. Depressive episode and the presence of anhedonia was assessed using the Mini International Neuropsychiatric Interview - Plus version (MINI Plus). Read More

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August 2018
1 Read

Gastric wall fat halo sign in patients without intestinal disease.

Clin Imaging 2018 Nov 30;54:31-36. Epub 2018 Nov 30.

Trabzon Kanuni Education and Research Hospital, Department of Radiology, 61080 Trabzon, Turkey.

Purpose: To investigate the relationship between gastric wall fat halo sign and visceral obesity with potentially associated diseases.

Materials And Methods: Between September 2015 and April 2017, 90 patients with gastric wall fat halo signs and 130 controls were prospectively evaluated. Patient height, weight, body mass index (BMI), sex, age, subcutaneous fat area (SFA), visceral fat area (VFA), total fat area (TFA), percentage of visceral fat (VF%) and the presence of colic or ileal fat halo signs, hepatic steatosis and aortic calcified plaques were recorded for the two groups. Read More

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November 2018
4 Reads

Computational study of new 1,2,3-triazole derivative of lithocholic acid: Structural aspects, non-linear optical properties and molecular docking studies as potential PTP 1B enzyme inhibitor.

Comput Biol Chem 2018 Nov 22;78:144-152. Epub 2018 Nov 22.

Department of Chemistry, University of Delhi, Delhi, 110007, India. Electronic address:

We have reported synthesis of a novel 1,2,3-triazole conjugate of lithocholic acid by 1,3-dipolar cycloaddition reaction. The molecular properties such as geometry, conformations, bond lengths and dihedral angles were investigated theoretically. The bond order analysis was performed using Wiberg bond order (WBO), Fuzzy bond order (FBO) and Laplacian bond order (MBO) method. Read More

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November 2018
1 Read

Genus Psoralea A review of the traditional and modern uses, phytochemistry and pharmacology.

J Ethnopharmacol 2018 Dec 3. Epub 2018 Dec 3.

CSIR-National Botanical Research Institute, Plant Transgenic Laboratory, P.O. Box 436, Rana Pratap Marg,Lucknow-226 001, U.P., India. Electronic address:

Ethnopharmacological Relevance: The genus Psoralea (Fabaceae) harbours 105 accepted species that are extensively used by local peoples and medicinal practitioners of China, India, and other countries for treatment of tooth decay, psoriasis, leucoderma, leprosy, kidney problems, tuberculosis, indigestion, constipation and impotence. Presently, pharmacological research reports are available on only few species namely Bituminaria bituminosa (Syn: P. bituminosa), P. Read More

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December 2018
3 Reads

First ethnobotanical inventory and phytochemical analysis of plant species used by indigenous people living in the Maromizaha forest, Madagascar.

J Ethnopharmacol 2018 Dec 3. Epub 2018 Dec 3.

Department of Agriculture, Forestry and Food Science, University of Torino, Torino, Italy.

Ethnopharmacological Relevance: Characterized by one of the highest rates of endemism and biodiversity in the world, Madagascar provides a wide variety of medicinal plants, that could represent a potential source of new drugs. The main aim of this study was to investigate the potential medicinal properties of the plant species used by indigenous people in Maromizaha forest and to provide the first ethnobotanical inventory of the area.

Materials And Methods: Data were collected through open semi-structured interviews with local informants, the reported plants were collected and identified to create a specimen herbarium. Read More

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December 2018
3 Reads

Enrichment of common carp (Cyprinus carpio) fingerlings diet with Psidium guajava: The effects on cutaneous mucosal and serum immune parameters and immune related genes expression.

Fish Shellfish Immunol 2018 Dec 3. Epub 2018 Dec 3.

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand. Electronic address:

The present study aimed at evaluation of possible effects of Psidium guajava as immunostimulant on mucosal and serum immunity, as well as related genes expression in common carp (Cyprinus carpio) fingerlings. In an eight weeks feeding trial, fish were fed with experimental diets containing guava leaf powder [GLP] (0, 0.25, 0. Read More

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December 2018
4 Reads

Prediction of neutrophil-to-lymphocyte ratio in the diagnosis and progression of autoimmune encephalitis.

Neurosci Lett 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, Jing Wu Road, Huaiyin District, Jinan, 250021, Shandong, China. Electronic address:

Objective: Autoimmune encephalitis (AIE) is a group of inflammatory disorders of the brain. The severity of AIE vary among individuals and it is always a challenge to predict. In this study, we measured the neutrophil-to-lymphocyte ratio (NLR), a novel potential biomarker of inflammatory status in other inflammatory diseases, in AIE patients and evaluated NLR as a biomarker for monitoring AIE progression. Read More

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December 2018
1 Read

Identifying critical process steps to protein stability during spray drying using a vibrating mesh or a two-fluid nozzle.

Eur J Pharm Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, the Netherlands. Electronic address:

The aim of this study was to identify critical steps to protein stability during spray drying using two different nozzle types: a vibrating mesh nozzle and a standard two-fluid nozzle in a Büchi B-90 spray dryer. l-Lactic dehydrogenase was used as a model protein as it is a heat and shear stress sensitive protein. Trehalose was used as excipient because of its excellent stabilizing capacities. Read More

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December 2018

Ecological niche modeling as a tool for prediction of the potential geographic distribution of Bacillus anthracis spores in Tanzania.

Int J Infect Dis 2018 Dec 3. Epub 2018 Dec 3.

Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.

Introduction: Anthrax is caused by the spore-forming, Gram-positive bacterium Bacillus anthracis. The aim of the study was to predict the potential distribution of B. anthracis in Tanzania and produce epidemiological evidence for management of anthrax outbreaks in the country. Read More

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December 2018
1 Read
2.330 Impact Factor

Exploring potential new galactomannan source of Retama reatam seeds for food, cosmetic and pharmaceuticals: Characterization and physical, emulsifying and antidiabetic properties.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Department of Industrial Engineering, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, SA, Italy.

In this study, physicochemical, interfacial and emulsifying properties of Retama reatam and guar galactomannans were comparatively investigated. The results showed that Retama reatam galactomannan is mainly composed of total carbohydrates (95.52%) and lower protein contents (0. Read More

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December 2018

One-pot carbonization of chitosan/P123/PdCl blend hydrogel membranes to N-doped carbon supported Pd catalytic composites for Ullmann reactions.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Zhejiang Key Laboratory of Alternative Technologies for Fine Chemicals Process, Shaoxing University, Shaoxing 312000, China. Electronic address:

Novel porous nitrogen-doped carbon supported Pd (Pd@N-C) catalytic composites were prepared by one-pot thermal carbonization of chitosan/poly(ethylene glycol)‑block‑poly(propylene glycol)‑block‑poly(ethylene glycol)/PdCl (CS/P123/PdCl) blend hydrogel membranes at different temperature in N atmosphere. The porous structure of the Pd@N-C catalytic composite was governed by both the addition of P123 and the carbonization temperature. At highest carbonization temperature of 900 °C, the prepared Pd@N-C catalytic composite from CS/P123/PdCl blend membrane showed the highest specific area (S) of 293. Read More

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December 2018

Draft genome analysis of lignocellulolytic enzymes producing Aspergillus terreus with structural insight of β-glucosidases through molecular docking approach.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Department of Animal Biotechnology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388110, Gujarat, India.

Members of the genus Aspergillus are extensively studied ascomycetes because of their ability to synthesize high value-added compounds and enzymes of industrial interest. Precise whole genome assembly and gene annotation are significant for gene functional analyses. Here, we report the draft genome sequencing, assembly and whole genome analysis of Aspergillus terreus P14_T3, isolated from rumen sample of cattle fed with coconut-coir. Read More

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December 2018

Physicochemical responses and microbiological changes of bream (Megalobrama ambycephala) to pectin based coatings enriched with clove essential oil during refrigeration.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710062, PR China. Electronic address:

The effectiveness of pectin coatings enriched with clove essential oil (CEO), as new edible coatings were investigated to preserve bream (Megalobrama ambycephala) fillets during refrigeration over a period of 15 days. All samples were analyzed for physicochemical (pH, PV, TBA and TVB-N), microbiological (Total viable count, Psychrophilic bacteria, Lactic acid bacteria, Enterobacteriaceae, Pseudomonas spp., HS producing bacteria) and organoleptic attributes. Read More

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December 2018

Gene polymorphisms of angiotensin-converting enzyme and angiotensinogen and risk of idiopathic ischemic stroke.

Gene 2018 Dec 3. Epub 2018 Dec 3.

Unidad de Investigación Médica en Trombosis, Hemostasia y Aterogénesis, H.G.R. No 1. Dr. "Carlos Mac Gregor Sánchez Navarro" Instituto Mexicano del Seguro Social, Gabriel Mancera No. 222, Colonia Del Valle, CP 03100 Ciudad de México, Mexico.

Objective: The renin-angiotensin system (RAS) is a hormonal signaling mechanism implicated in the atherosclerosis and regulation of blood pressure. Angiotensin-converting enzyme (ACE) a key enzyme in the RAS, plays important roles in vascular remodeling atherosclerosis, and ischemic stroke. The aim of this study was to examine the possible contribution of the I/D in the ACE gene, M235T and T174M in the angiotensinogen (AGT) gene polymorphisms with ischemic stroke in young Mexican population. Read More

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December 2018
1 Read

Electro-acupuncture attenuates the mice premature ovarian failure via mediating PI3K/AKT/mTOR pathway.

Life Sci 2018 Dec 3. Epub 2018 Dec 3.

College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:

Aims: Electro-acupuncture (EA) is frequently recommended as a complementary therapy for premature ovarian failure (POF) in the clinical. However, little information exists about its potential treatment mechanisms. The study was designed to observe the effect of EA to ovarian function and fertility in POF mice model, and investigated its potential mechanisms on PI3K/AKT/mTOR signaling pathway. Read More

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December 2018

Development and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity.

Neurobiol Dis 2018 Dec 3. Epub 2018 Dec 3.

Laboratory of Functional Neurochemistry, IRCCS Mondino Foundation, Pavia, Italy. Electronic address:

GBA1 gene encode for the lysosomal membrane protein glucocerebrosidase (GCase). GBA1 heterozygous mutations profoundly impair GCase activity and are currently recognized as an important risk factor for the development of Parkinson's disease (PD). Deficits in lysosomal degradation pathways may contribute to pathological α-synuclein accumulation, thereby favoring dopaminergic neuron degeneration and associated microglial activation. Read More

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December 2018

Economic cost of malaria at household in high and low transmission areas of central India.

Authors:
Mrigendra Singh

Acta Trop 2018 Dec 3. Epub 2018 Dec 3.

ICMR-National Institute of Malaria Research Field Unit Jablpur, Epidemiology, ICMR-NIRTH Campus, Nagpur Road, 482003, Jabalpur, Madhya Pradesh, India. Electronic address:

The cost burden of malaria at the household level, resulting from complex social, economic, and epidemiological factors, is enormous. This study was carried out to estimate the economic burden of malaria at the household level in low and high malaria transmission areas of central India. We conducted surveys with households in which at least one member had suffered from malaria in the three months preceding the survey. Read More

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December 2018
1 Read

Does Maternal Age at Retrieval Influence the Implantation Potential of Euploid Blastocysts?

Am J Obstet Gynecol 2018 Dec 3. Epub 2018 Dec 3.

The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY 10021.

Background: Age-related decline in reproductive potential is mainly due to the increased incidence of aneuploidy. Furthermore, two recent studies have shown that euploid embryos of older women may have a lower implantation potential compared to those of younger women, suggesting that aging might compromise embryos beyond their ploidy status. However, the inherent limitations of these studies preclude solid conclusions. Read More

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December 2018
2 Reads

Extent of Lymphadenectomy and Postoperative Major Complications Among Women with Endometrial Cancer Treated with Minimally Invasive Surgery.

Am J Obstet Gynecol 2018 Dec 3. Epub 2018 Dec 3.

Northwestern University, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chicago, IL, USA; Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Center for Healthcare Studies, Institute for Public Health in Medicine, Chicago, IL.

Background: In patients with endometrial cancer sentinel lymphadenectomy is used to accurately prognosticate extent of disease and has been proposed as a method to decrease the incidence of medical and surgical complications associated with more extensive lymphadenectomy. It is unknown if patients who undergo traditional lymphadenectomy experience major postoperative complications at the same rates as those who undergo sentinel lymphadenectomy or those who do not undergo lymphadenectomy.

Objective: To compare the incidence of major postoperative complications among endometrial cancer patients undergoing total laparoscopic hysterectomy with traditional lymphadenectomy versus sentinel or no lymphadenectomy. Read More

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December 2018
2 Reads

Is physical activity associated with resting heart rate in boys and girls? A representative study controlled for confounders.

J Pediatr (Rio J) 2018 Dec 3. Epub 2018 Dec 3.

Universidade Estadual Paulista, Departamento de Educação Física, Presidente Prudente, SP, Brazil. Electronic address:

Objective: Investigate the relationship between different domains of physical activity and resting heart rate (RHR) in boys and girls.

Method: The sample included 1011 adolescents, aged between 10 and 17 years. RHR was measured by a heart rate monitor and physical activity was assessed in total and in three different domains (school, occupational, and sports practice) by a questionnaire. Read More

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December 2018

Shining Sunlight on Industry Payments in Oral and Maxillofacial Surgery: The Sunshine Act.

J Oral Maxillofac Surg 2018 Nov 12. Epub 2018 Nov 12.

Assistant Professor, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA.

Purpose: To characterize industry payments to oral and maxillofacial surgeons (OMSs) and to determine the accuracy of the Centers for Medicare and Medicaid Services (CMS) Open Payments Databases.

Materials And Methods: This was a cross-sectional study of the CMS General and Research Payments Databases in 2016 for clinicians categorized as OMSs. General payments include consulting fees, honoraria, gifts, entertainment, food and beverage, travel and education, and others. Read More

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November 2018
1 Read

Myocardial Injury in Critically Ill Patients with Community-acquired Pneumonia: A Cohort Study.

Ann Am Thorac Soc 2018 Dec 6. Epub 2018 Dec 6.

University Medical CenterUtrecht, Utrecht, Netherlands.

Rationale: Myocardial injury, as reflected by elevated cardiac troponin levels in plasma, is common in patients with community-acquired pneumonia (CAP), but its temporal dynamics and etiology remain unknown.

Objectives: Our aim was to determine the incidence of troponin release in patients with CAP and identify risk factors which may point to underlying etiologic mechanisms.

Methods: We included consecutive patients admitted with severe CAP to two intensive care units in the Netherlands between 2011 and 2015. Read More

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December 2018
1 Read

Cost of medical attention in patients with Chronic Obstructive Pulmonary Disease

Rev Med Inst Mex Seguro Soc 2018 11 30;56(4):371-378. Epub 2018 Nov 30.

Instituto Mexicano del Seguro Social, Unidad de Investigación Epidemiológica y en Servicios de Salud. Querétaro, Querétaro, México

Background: The chronic obstructive pulmonary disease is a preventable entity, when it develops the patient suffers severe complications, with a high economic impact for the patient and for health services.

Objetive: To determine the cost of medical care in patients with chronic obstructive pulmonary disease (COPD).

Methods: Using a cost design, the files of patients with COPD who attended the pulmonology clinic were analyzed. Read More

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November 2018

[Interlocking femoral nail and total knee Arthroplasty in one stage for a patient with a femoral diaphyseal stress fracture].

Acta Ortop Mex 2018 May-Jun;32(3):163-166

Servicio de Cirugía Ortopédica y Traumatología, Hospital de Sabadell. Institut Universitari Parc Taulí Universitat Autònoma de Barcelona, España.

We present the case of an 81-year-old woman who was followed up by the Rheumatology Service for osteoporosis and treated with bisphosphonates for more than five years. She reported a fracture of the distal third of the contralateral femur by a low energy mechanism, treated with retrograde intramedullary nailing the previous year. She presented a clinic of cruralgia and left gonalgia, without previous trauma. Read More

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December 2018

[Continuous vs. intermitent intravenous analgesia for primary total knee replacement: analysis of the quality of the pain control, hospital stay and costs].

Acta Ortop Mex 2018 May-Jun;32(3):134-139

Instituto Allende de Cirugía Reconstructiva de los Miembros, Córdoba-Argentina.

Background: The International Association for the Study of Pain (IASP) defines pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Total knee arthroplasty is one of the orthopedic surgeries that manifests more pain in the first 24-48 hours, needing a multimodal analgesic therapy. The objective of this work is to compare two different intravenous analgesic modes applied to patients undergoing a primary total knee arthroplasty, analyzing the quality of pain control, hospital stay and costs. Read More

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December 2018
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[Prevalence of osteoporosis and osteopenia in patients occupationally active].

Acta Ortop Mex 2018 May-Jun;32(3):131-133

Clínica de Detección y Diagnóstico Automatizado, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Ciudad de México.

Background: Osteoporosis is a public health problem worldwide, affecting more than 200 million people. It is estimated that 30 to 50% of postmenopausal women suffer from it. According to the International Osteoporosis Foundation (IOF), osteoporosis is a disease characterized by a decrease in the density and quality of bones. Read More

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December 2018
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