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    Long-term in-vivo effect of various restorative materials on enamel and dentin of primary molars.
    Quintessence Int 2017 Jul 4:1-6. Epub 2017 Jul 4.
    Objective: To explore the long-term in-vivo effect of different dental restorative materials on the surrounding enamel and dentin, in primary molars.

    Method And Materials: Sixteen naturally exfoliated primary molars restored with amalgam, compomer, and glass-ionomer cement were collected after 2 to 5 years of function in the mouth. Four intact molars served as control. Read More

    Thirty-Six-Month Clinical Comparison of Bulk Fill and Nanofill Composite Restorations.
    Oper Dent 2017 Jun 5. Epub 2017 Jun 5.
    Objectives: The aim of this study was to evaluate the clinical performance of a nanofill and a bulk fill resin composite in class II restorations.

    Methods And Materials: In accordance with a split-mouth design, 50 patients received at least one pair of restorations, restored with a nanofill resin composite (Filtek Ultimate [FU]) and with a bulk fill resin composite (Tetric EvoCeram Bulk Fill [TB]). Each restorative resin was used with its respective adhesive system according to the manufacturers' instructions. Read More

    Whitening dentifrice and tooth surface discoloration-a systematic review and meta-analysis.
    Int J Dent Hyg 2017 Jun 2. Epub 2017 Jun 2.
    Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
    Objective: The aim of this systematic review was to assess the effect of a whitening dentifrice (WDF) relative to a regular dentifrice (RDF) on the reduction of natural extrinsic tooth surface discoloration (ETD).

    Materials And Methods: The MEDLINE-PubMed, Cochrane-CENTRAL and EBSCO-Dentistry and Oral Sciences databases were searched, up to April 2017. The inclusion criteria were as follows:(randomized)controlled clinical trials, healthy subjects ≥18 years of age, studies comparing WDF with RDF, a follow-up period of at least 6 weeks and studies scoring ETD as the stain area/extent, stain intensity or a composite score. Read More

    Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis.
    N Engl J Med 2017 06;376(22):2122-2133
    From the Cumming School of Medicine and the Hotchkiss Brain Institute, Calgary, AB (L.M.M., G.C., J.G., M.Y., M.D.H., V.W.Y.), the University of British Columbia, Vancouver (D.K.B.L., A.L.T., A.R.), the University of Montreal, Montreal (P.D.), Western University, London, ON (M.K.), Fraser Health MS Clinic, Burnaby, BC (G.V.), the University of Ottawa and the Ottawa Hospital Research Institute, Ottawa (M.S.F.), Dalhousie University, Halifax, NS (V.B.), the University of Alberta, Edmonton (G.B.), the University of Manitoba, Winnipeg (J.J.M.), Clinique Neuro Rive-Sud, Greenfield Park, QC (F.G.), the University of Toronto, Toronto (L.L.), and CHA-Hôpital Enfant-Jésus, Quebec, QC (M.T.) - all in Canada; and Tufts University, Boston (M.E.).
    Background: On the basis of encouraging preliminary results, we conducted a randomized, controlled trial to determine whether minocycline reduces the risk of conversion from a first demyelinating event (also known as a clinically isolated syndrome) to multiple sclerosis.

    Methods: During the period from January 2009 through July 2013, we randomly assigned participants who had had their first demyelinating symptoms within the previous 180 days to receive either 100 mg of minocycline, administered orally twice daily, or placebo. Administration of minocycline or placebo was continued until a diagnosis of multiple sclerosis was established or until 24 months after randomization, whichever came first. Read More

    The effect of a tooth/tongue gel and mouthwash regimen on morning oral malodour: A 3-week single-blind randomized clinical trial.
    Int J Dent Hyg 2017 May 24. Epub 2017 May 24.
    Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands.
    Aim: To compare the effects of a regimen consisting of a tooth/tongue gel, tongue cleaner and mouthwash with the effects of using standard fluoride dentifrice on the organoleptic oral malodour score (ORG) and volatile sulphur compounds (VSCs).

    Materials And Methods: A total, 66 non-dental students participated in a 3-week parallel, single-blind, randomized, controlled clinical trial. The test group used a tongue cleaner, a tooth/tongue gel and mouthwash containing amine fluoride/stannous fluoride and zinc lactate as oral malodour counteractive. Read More

    Self-repaired Process of a Traumatized Maxillary Central Incisor with Pulp Infarct after Horizontal Root Fracture Monitored by Laser Doppler Flowmetry Combined with Tissue Oxygen Monitor.
    J Endod 2017 Jul 17;43(7):1218-1222. Epub 2017 May 17.
    State Key Laboratory of Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
    Achieving a precise diagnosis of the pulp status of traumatized teeth is difficult. The time to interfere through endodontic treatment for these teeth is greatly dependent on the doctor's experience. A 24-year-old male patient suffered a traumatic injury to tooth #9 that resulted in an apical root horizontal fracture 3 days before he came to the hospital. Read More

    An Evidence-based Review of the Efficacy of Treatment Approaches for Immature Permanent Teeth with Pulp Necrosis.
    J Endod 2017 Jul 13;43(7):1052-1057. Epub 2017 May 13.
    Department of Endodontics, New York University College of Dentistry, New York, New York.
    Introduction: Two fundamental assumptions for teeth treated with regenerative endodontic procedures (REPs) are (1) that the clinical outcome is comparable with the traditional techniques of calcium hydroxide apexification and mineral trioxide aggregate apical barrier techniques and (2) that REPs will result in further root maturation.

    Methods: A systematic review of the electronic databases (Scopus, PubMed, and Web of Science) involved a search for studies that used quantitative assessments of root maturation. The search terms were "dental pulp," "regenerative endodontic therapy," "revascularization," and "revitalization. Read More

    Bovine Tooth Discoloration Induced by Endodontic Filling Materials for Primary Teeth.
    Int J Dent 2017 5;2017:7401962. Epub 2017 Apr 5.
    Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil.
    Objective. This study evaluated the discoloration potential of endodontic materials used in primary teeth. Material and Methods. Read More

    Functional and esthetic rehabilitation of a child with amelogenesis imperfecta: a case report.
    Gen Dent 2017 May-Jun;65(3):e18-e20
    Amelogenesis imperfecta (AI) is a tooth disorder characterized by the abnormal development of the enamel in response to mutations in the genes involved in amelogenesis. The objective of this article is to present the clinical case of a child with AI in the primary dentition phase. A 4-year-old boy was presented to a clinic by his mother, who complained that her son's smile esthetics were compromised by "weak and yellow teeth. Read More

    Rare sequelae in the permanent successor due to trauma in the primary incisor: a case report.
    Gen Dent 2017 May-Jun;65(3):62-64
    Severe dental trauma-such as intrusion or avulsion-to the primary dentition in infants and toddlers may cause developmental disturbances in the permanent successor. In this case, a 9-year-old boy was referred for treatment due to the absence of his permanent maxillary right central incisor. The mother reported avulsion of the corresponding primary tooth when the patient was 2 years old. Read More

    [Comparison of clinical effects of Co-Cr alloy cast post-core and everStick fiber post in restoration of labially or lingually inclined maxillary central incisor].
    Shanghai Kou Qiang Yi Xue 2017 Feb;26(1):89-93
    Department of Prosthodontics, Shanghai Stomatological Disease Center, Shanghai Stomatological Hospital. Shanghai 200031, China.
    Purpose: To compare the clinical effect of Co-Cr alloy cast post-core and everStick fiber post in restoration of maxillary central incisor with labial or lingual inclination, and provide theoretical basis for clinical application.

    Methods: Ninety-seven labially or lingually inclined maxillary central incisors were treated in our hospital from March 2012 to March 2014. The patients were randomly divided into group A (n=49) and group B (n=48), and received post -core and crown restoration. Read More

    Analyses of MMP20 Missense Mutations in Two Families with Hypomaturation Amelogenesis Imperfecta.
    Front Physiol 2017 20;8:229. Epub 2017 Apr 20.
    Department of Molecular Genetics and Dental Research Institute, School of Dentistry, Seoul National UniversitySeoul, Korea.
    Amelogenesis imperfecta is a group of rare inherited disorders that affect tooth enamel formation, quantitatively and/or qualitatively. The aim of this study was to identify the genetic etiologies of two families presenting with hypomaturation amelogenesis imperfecta. DNA was isolated from peripheral blood samples obtained from participating family members. Read More

    Effects of clarithromycin treatment in scrub typhus in children: comparison with chloramphenicol and azithromycin.
    Korean J Pediatr 2017 Apr 25;60(4):124-127. Epub 2017 Apr 25.
    Department of Pediatrics, Chonbuk National University Children's Hospital, Jeonju, Korea.
    Purpose: Chloramphenicol and tetracycline are not recommended for treating scrub typhus in pediatric patients because of potential side effects, such as aplastic anemia or tooth discoloration. While clarithromycin has recently been used in adults, few reports have been published on its effects in pediatric patients. We report the clinical profiles of pediatric scrub typhus and the effects of clarithromycin on scrub typhus in children. Read More

    Correction of a Single Discolored Anterior Tooth Due to Internal Resorption: A Clinical Report.
    Compend Contin Educ Dent 2017 May;38(5):e13-e16
    Assistant Professor, Oral Rehabilitation Department, Dental College of Georgia at Augusta University, Augusta, Georgia.
    For patients with a single discolored tooth who desire to have it lightened, a thorough examination and radiographic analysis need to be performed prior to initiating any bleaching treatment so that the cause of the discoloration can be determined. Underlying pathology, such as internal resorption, is often asymptomatic and difficult to diagnose and if left untreated could result in tooth loss. This article describes a case of a patient with a discolored maxillary central incisor resulting from internal resorption and the subsequent endodontic and bleaching therapy performed to resolve the pathology and achieve an acceptable esthetic result. Read More

    Provider Perceptions of Treatment Options for Immature Permanent Teeth.
    J Endod 2017 Jun 27;43(6):910-915. Epub 2017 Apr 27.
    Department of Endodontics, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina. Electronic address:
    Introduction: Current treatment options for immature permanent teeth with pulpal necrosis include both apexification and regenerative endodontics. The purpose of this study was to survey endodontists on the use of these 2 treatment options.

    Methods: Surveys were created by using Qualtrics and Teleform software and distributed by using the Salant and Dillman method. Read More

    Spectrophotometric analysis of fluorescent zirconia abutments compared to "conventional" zirconia abutments: A within subject controlled clinical trial.
    Clin Implant Dent Relat Res 2017 Apr 24. Epub 2017 Apr 24.
    Division of Fixed Prosthodontics and Biomaterials, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.
    Background: Zirconia abutments are frequently used for implant-supported single crowns. Even though demonstrating esthetic benefits compared to metal abutments, zirconia abutments lead to an increased brightness of the peri-implant mucosa compared to natural teeth and are not ideal from an esthetic point of view.

    Purpose: To test whether or not a fluorescent hybrid zirconia abutment offers superior esthetics compared to a non-fluorescent one-piece zirconia abutment based on spectrophotometric analysis. Read More

    Minocycline-Induced Hyperpigmentation in a Patient Treated with Erlotinib for Non-Small Cell Lung Adenocarcinoma.
    Case Rep Oncol 2017 Jan-Apr;10(1):156-160. Epub 2017 Feb 15.
    Walter Reed National Military Medical Center, Bethesda, MD, USA.
    Introduction: While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxycycline.

    Case: We present a case of an 87-year-old man who developed a severe papulopustular skin eruption secondary to erlotinib therapy for NSCLC. Control of the eruption with 100 mg of minocycline twice daily for 8 months eventually led to blue-gray skin hyperpigmentation. Read More

    The end of a dogma: the safety of doxycycline use in young children for malaria treatment.
    Malar J 2017 Apr 13;16(1):148. Epub 2017 Apr 13.
    Unité de Parasitologie et d'Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, HIA Laveran, Boulevard Laveran, 13013, Marseille, France.
    Anti-malarial drug resistance to chloroquine and sulfadoxine-pyrimethamine has spread from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to artemisinin-based combination therapy (ACT) in Southeast Asia highlights the need to identify new anti-malarial drugs. Doxycycline is recommended for malaria chemoprophylaxis for travel in endemic areas, or in combination with the use of quinine for malaria treatment when ACT is unavailable or when the treatment of severe malaria with artesunate fails. Read More

    Crown discoloration promoted by materials used in regenerative endodontic procedures and effect of dental bleaching: spectrophotometric analysis.
    J Appl Oral Sci 2017 Mar-Apr;25(2):234-242
    Universidade Federal de Santa Catarina, Departamento de Odontologia, Florianópolis, Santa Catarina, Brasil.
    Objectives: To assess tooth crown's color after intracanal treatment with triple antibiotic paste (TAP) or calcium hydroxide (CH); cervical sealing with glass ionomer cement (GIC) or mineral trioxide aggregate (MTA); and bleaching with carbamide peroxide.

    Material And Methods: After pulp removal and color spectrophotometer measurement, 50 bovine incisors were divided into 4 experimental groups and one control (untreated). Experiments were performed in phases (Ph). Read More

    Color stability of ceramic laminate veneers cemented with light-polymerizing and dual-polymerizing luting agent: A split-mouth randomized clinical trial.
    J Prosthet Dent 2017 Apr 3. Epub 2017 Apr 3.
    Adjunct Professor, Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Santa Maria, Rio Grande do Sul, Brazil.
    Statement Of Problem: The color stability of luting agents influences the esthetics of ceramic laminate veneers. Clinical studies that have evaluated the color changes of veneers cemented to enamel with light- and dual-polymerizing resin cement are lacking.

    Purpose: The purpose of this split-mouth randomized clinical trial was to evaluate the color change and marginal discoloration of dual- and light-polymerizing cement used for cementation of ceramic laminate veneers. Read More

    An in vitro analysis model for investigating the staining effect of various chlorhexidine-based mouthwashes.
    J Clin Exp Dent 2017 Mar 1;9(3):e410-e416. Epub 2017 Mar 1.
    Prof, PhD, UFR d'odontologie. 1, Place A. Ricordeau, 44082, Nantes cedex2.
    Background: There are different mouthwashes containing chlorhexidine in different concentrations, as well as various excipients. Chlorhexidine induce stains or discoloration in teeth and mucous membranes. The aim of this work was to design a model to reproduce in vitro staining associated with the use of different mouthwashes containing chlorhexidine. Read More

    A Case Report of Dilacerated Crown of a Permanent Mandibular Central Incisor.
    J Dent (Tehran) 2016 Nov;13(6):448-452
    Assistant Professor, Department of Endodontics, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran.
    Trauma to primary teeth can lead to devastating sequels in development of permanent successors. The disturbance may range from enamel hypoplasia and/or hypo-calcification to arrest of dental bud development. Crown dilaceration of permanent teeth is one of the consequences of trauma to deciduous teeth mainly due to intrusion or avulsion. Read More

    Tooth Discoloration Resulting from a Nano Zinc Oxide-Eugenol Sealer.
    Iran Endod J 2017 ;12(1):74-77
    Student Research Committee (SRC), Mashhad University of Medical Sciences, Mashhad, Iran.
    Introduction: A desirable quality of any endodontic sealer is its ability to be tooth color friendly. Therefore the aim of the present study was to evaluate the tooth discoloration potential of a nano zinc oxide-eugenol (NZOE) sealer.

    Methods And Materials: In order to evaluate tooth discoloration, the pulp chamber of 60 human maxillary central and lateral incisors were filled with one of the sealers, naming AH-26 (resin-based sealer), Pulpdent sealer (ZOE-based) and a NZOE experimental sealer. Read More

    Effect of Silver Diamine Fluoride and Potassium Iodide Treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration.
    Int J Mol Sci 2017 Feb 6;18(2). Epub 2017 Feb 6.
    Faculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.
    This study investigated the effect of silver diamine fluoride (SDF) and potassium iodide (KI) treatment on secondary caries prevention and tooth discolouration in glass ionomer cement (GIC) restoration. Cervical GIC restorations were done on 30 premolars with: Group 1, SDF + KI; Group 2, SDF (positive control); Group 3, no treatment (negative control). After cariogenic biofilm challenge, the demineralisation of dentine adjacent to the restoration was evaluated using micro-computed tomography (micro-CT) and Fourier transform infrared (FTIR) spectroscopy. Read More

    Clinical evaluation of fiber-reinforced composite crowns in pulp-treated primary molars: 12-month results.
    Eur J Dent 2016 Oct-Dec;10(4):522-528
    Dental Material Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
    Objective: The aim of this study was to evaluate the clinical performance of tooth-colored fiber-reinforced composite (FRC) crowns in pulp-treated second primary mandibular teeth.

    Materials And Methods: This split-mouth randomized, clinical trial performed on 67 children between 3 and 6 years with two primary mandibular second molars requiring pulp treatment. After pulp therapy, the teeth were randomly assigned to stainless steel crown (SSC) or FRC crown groups. Read More

    Evaluation of pit-and-fissure sealants placed with four different bonding protocols: a randomized clinical trial.
    Int J Paediatr Dent 2016 Dec 26. Epub 2016 Dec 26.
    Department of Paedodontics and Preventive Dentistry, Manipal College of Dental Sciences, Manipal University, Mangalore, India.
    Background: Application of adhesive after acid etching may increase the retention of pit-and-fissure sealants and improve clinical effectiveness.

    Aims: To clinically evaluate the retention, marginal discoloration and caries incidence of pit-and-fissure sealants applied using four bonding protocols: conventional acid etching, etch-and-rinse adhesive, multimode universal adhesive and self-etch adhesive used after acid etching.

    Design: In this split-mouth design study, the four adhesive protocols were randomly assigned to the four erupted, non-carious first permanent molars and involved 52 patients between 6 and 10 years of age. Read More

    Diagnostic guide enabling distinction between taphonomic stains and enamel hypomineralisation in an archaeological context.
    Arch Oral Biol 2017 Feb 10;74:28-36. Epub 2016 Nov 10.
    Université de Bordeaux, UFR des Sciences Odontologiques, Bordeaux, France; Université de Bordeaux, PACEA, UMR 5199, Pessac, France.
    Objective: Molar Incisor Hypomineralisation (MIH) is a structural anomaly that affects the quality of tooth enamel and has important consequences for oral health. The developmentally hypomineralised enamel has normal thickness and can range in colour from white to yellow or brown with or without surface breakdown. The possibility of finding MIH in 'ancient populations' could downplay several current aetiological hypotheses (e. Read More

    Dental Treatment Needs among Children and Adolescents Residing in an Ugandan Orphanage.
    J Clin Pediatr Dent 2016;40(6):486-489
    Background: Previous studies focused on the dental caries status of East African children and not on their overall dental needs. Urban children consume more sugar-rich foods.

    Objectives: To assess overall dental treatment needs of children living in an orphanage in Uganda. Read More

    Is resin infiltration an effective esthetic treatment for enamel development defects and white spot lesions? A systematic review.
    J Dent 2017 Jan 25;56:11-18. Epub 2016 Oct 25.
    Department of Pediatric Dentistry and Orthodontic, Federal University of Rio de Janeiro - UFRJ, Postal code: 68066, Cidade Universitária, CCS, CEP 21941-971, Rio de Janeiro, RJ, Brazil.
    Objectives: To determine if resin infiltration is an effective treatment for improving the esthetic appearance of tooth discoloration resulting from development defects of enamel (EDD) and white spot lesions (WSL) by means of a systematic review.

    Data Sources: A comprehensive search was performed in PubMed, Scopus, Web of Science, LILACS, BBO Library, Cochrane Library, and SIGLE, as well as in the abstracts of IADR conference, and in the clinical trials registry.

    Study Selection: Clinical studies in patients with whitish tooth discoloration, in which the resin infiltration technique was applied, were included. Read More

    The Use of Resin Composite Layering Technique to Mask Discolored Background: A CIELAB/CIEDE2000 Analysis.
    Oper Dent 2017 Mar/Apr;42(2):165-174. Epub 2016 Nov 1.
    The purpose of this study was to evaluate the ability of three resin composite systems to mask a severely discolored background by the application of a layering technique through CIELAB and CIEDE2000 analysis. Ninety 1.5-mm-thick disc specimens were produced from three different resin composite restoration systems: IPS Empress Direct (Ivoclar Vivadent), Charisma Diamond (Heraeus Kulzer), and Filtek Z350 XT (3M-ESPE). Read More

    Discoloration Potential of Endodontic Sealers: A Brief Review.
    Iran Endod J 2016 ;11(4):250-254
    Department of Endodontics, Dental Branch, Islamic Azad University of Medical Sciences, Tehran, Iran;; Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Tooth discoloration induced by endodontic sealers, is a common finding that impairs aesthetic outcome of endodontic treatment. The aim of the present mini literature review, was to summarize the existing data on discoloration potential of different endodontic sealers. The research covered the article published in PubMed and Google Scholar from 2000 to 2015. Read More

    Comparison of the Potential Discoloration Effect of Bioaggregate, Biodentine, and White Mineral Trioxide Aggregate on Bovine Teeth: In Vitro Research.
    J Endod 2016 Dec 21;42(12):1815-1818. Epub 2016 Oct 21.
    Department of Pediatric Dentistry, Gazi University Faculty of Dentistry, Emek, Ankara, Turkey.
    Introduction: Tricalcium silicate cements can be used for pulp capping, pulpotomies, apical barrier formation in teeth with open apices, repair of root perforations, regenerative endodontics, and root canal filling. The aim of this study was to evaluate and compare the discoloration potential of 3 different tricalcium cements using a bovine tooth model.

    Methods: Forty bovine anterior teeth have been used for the study. Read More

    Color stability of mineral trioxide aggregate and calcium enriched mixture cement.
    J Investig Clin Dent 2016 Nov 14;7(4):341-346. Epub 2015 Jul 14.
    Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Aim: To assess the effect of light irradiation and different immersion media on discoloration of white mineral trioxide aggregate (WMTA) and calcium enriched mixture (CEM) cement at different time intervals.

    Methods: Enamel sections of 12 teeth were removed and six cavities were prepared in each tooth. The cavities were filled randomly either with WMTA or CEM and covered with transparent sealant. Read More

    Prospective cohort clinical study assessing the 5-year survival and success of anterior maxillary zirconia-based crowns with customized zirconia copings.
    J Prosthet Dent 2017 Feb 17;117(2):226-232. Epub 2016 Oct 17.
    Research Associate Professor, Department of Dental Public Health Sciences, University of Washington, Seattle, Wash.
    Statement Of Problem: Studies evaluating anterior zirconia-based crowns are limited.

    Purpose: The purpose of this prospective cohort clinical study was to assess the efficacy of zirconia-based anterior maxillary crowns with 0.3-mm customized copings at the cervical third and anatomical design elsewhere for up to 5 years of service. Read More

    Do parents and children perceive molar-incisor hypomineralization as an oral health problem?
    Int J Paediatr Dent 2016 Oct 17. Epub 2016 Oct 17.
    School of Health Sciences, University of Brasília, Brasilia, Brazil.
    Background: Very little is known about how patients perceive molar-incisor hypomineralization (MIH).

    Aim: The aim of this study was to identify whether parents and children perceive opacities associated with MIH as an oral health problem.

    Design: A case-control study was designed in which 131 children diagnosed with MIH were matched by age, sex, and school to 131 children without MIH. Read More

    Influence of Enamel Thickness on Bleaching Efficacy: An In-Depth Color Analysis.
    Open Dent J 2016 31;10:438-445. Epub 2016 Aug 31.
    Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, Av. Limeira, 901, Areião, 13414-903, Piracicaba, SP, Brazil.
    This study evaluated the influence of different enamel thicknesses and bleaching agents on treatment efficacy in-depth by spectrophotometry color analysis. Eighty bovine dental fragments were previously stained in black tea solution and randomly assigned into eight groups (n=10), 1.75mm dentin thickness and different enamel thicknesses as follows: 0. Read More

    Efficacy of E-Learning via the Website of Tehran University of Medical Sciences for Diagnosing Tooth Discolorations and Treatment Planning by Senior Dental Students.
    Acta Med Iran 2016 Aug;54(8):536-541
    Department of Operative Dentistry, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
    The efficacy of methods like e-learning as a supplement to traditional face-to-face instruction needs to be evaluated in dental courses. This study aimed to assess the efficacy of posting case presentations on one of the educational websites of  the virtual school of Tehran University of Medical Sciences called "SARMAD" to enhance the ability of senior dental students to diagnose tooth discolorations and offer treatment plans. This experimental study had a pre-test/post-test control group design and was conducted on 63 senior dental students. Read More

    Tooth replacements in young adults with severe hypodontia: Orthodontic space closure, dental implants, and tooth-supported fixed dental prostheses. A follow-up study.
    Am J Orthod Dentofacial Orthop 2016 Oct;150(4):620-626
    Associate professor, Department of Orthodontics, Faculty of Dentistry, University of Oslo, Oslo, Norway.
    Introduction: Children with severe hypodontia have a substantial impairment of their dental health starting early in life. The purpose of this study was to describe types and locations of substitutes for missing teeth in patients with severe hypodontia and to compare the crown and soft tissue morphologies of orthodontic space closure, dental implants, and tooth-supported fixed dental prostheses for replacing teeth in the anterior region.

    Methods: Fifty patients missing 6 or more teeth and aged 18 years or older (mean age, 25. Read More

    Four year Evaluation of Proximal Resin Infiltration in Adolescents.
    Acta Stomatol Croat 2015 Dec;49(4):304-8
    University of Tirana, School of Dentistry, Tirana, Albania.
    Aim: Resin infiltration of proximal lesions is a new approach to stopping caries progression. Therefore, the aim of the present study was to evaluate four-year efficacy of proximal infiltrates in adolescents.

    Materials And Methods: In ten adolescents, a total of 21 proximal infiltrates (ICON® (DMG, Germany) were applied to initial proximal lesions of permanent incisors and premolars according to the manufacturer's instruction. Read More

    A comparative evaluation of dental caries status among hearing-impaired and normal children of Malda, West Bengal, evaluated with the Caries Assessment Spectrum and Treatment.
    J Indian Soc Pedod Prev Dent 2016 Oct-Dec;34(4):306-9
    Department of Pedodontics and Preventive Dentistry, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India.
    Context: Dental caries is one of the major modern-day diseases of dental hard tissue. It may affect both normal and hearing-impaired children.

    Aims: This study is aimed to evaluate and compare the prevalence of dental caries in hearing-impaired and normal children of Malda, West Bengal, utilizing the Caries Assessment Spectrum and Treatment (CAST). Read More

    Prognosis of Indirect Composite Resin Cuspal Coverage on Endodontically Treated Premolars and Molars: An In Vivo Prospective Study.
    J Prosthodont 2016 Sep 23. Epub 2016 Sep 23.
    Full Professor and Chairman of the Implantology Department, Lisbon University, School of Dental Medicine, Lisbon, Portugal.
    Purpose: This prospective clinical study evaluated the success rate of indirect composite resin cuspal coverage on endodontically treated molars and premolars and the survival rate of the restored teeth.

    Materials And Methods: One hundred fifty endodontically treated teeth were restored with total resin cuspal coverage and randomly selected for the study. Patients were recalled after 2 to 5 years for clinical evaluation. Read More

    A Comparison of the Discoloration Potential for EndoSequence Bioceramic Root Repair Material Fast Set Putty and ProRoot MTA in Human Teeth: An In Vitro Study.
    J Esthet Restor Dent 2017 Feb 17;29(1):59-67. Epub 2016 Sep 17.
    Dental intern, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
    Objective: To compare the discoloration potential of Endosequence Bioceramic Root Repair Material fast set putty (ERRMF) and ProRoot MTA (PMTA) when placed coronally in human extracted teeth over a 4-month period.

    Methodology: Forty-eight premolars were sectioned 2 mm below the cementoenamel junction. The pulp chambers were cleaned chemo-mechanically. Read More

    Regenerative Endodontic Treatment versus Apical Plug in Immature Teeth: Three-Year Follow-Up.
    J Clin Pediatr Dent 2016;40(5):356-60
    This report compares and evaluates the treatment outcomes of regenerative endodontic treatment and apical plug as two accepted treatment protocols in a pair of necrotic immature maxillary central incisors of a 12-year old female. The patient was referred complaining of a dull pain and swelling in her upper lip area. She had a history of trauma to the anterior maxilla two years earlier. Read More

    Surface Properties and Color Stability of Resin-Infiltrated Enamel Lesions.
    Oper Dent 2016 Nov/Dec;41(6):617-626. Epub 2016 Sep 2.
    Objectives: To examine the surface topographies, microhardness, and color stability of resin-infiltrated enamel lesions before and after aging challenges in vitro using three-dimensional laser scanning profilometry, surface microhardness testing, spectrophotometry, and scanning electron microscopy.

    Methods: Forty human third molars were embedded in epoxy resin, and each tooth was prepared to have two white spot lesions and one sound enamel area. One white spot lesion received resin infiltration and the other was untreated. Read More

    Management of coronal discolouration following a regenerative endodontic procedure in a maxillary incisor.
    Aust Dent J 2017 Mar 6;62(1):111-116. Epub 2017 Feb 6.
    The Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia.
    Pulpal necrosis and infection in an immature anterior tooth subsequent to traumatic injury is a challenging situation. Regenerative endodontics, resulting in continued development of the tooth, provides a biological response to this clinical challenge. Regenerative endodontic procedures require disinfection of the infected root canal and sealing of the pulp canal space. Read More

    An application of microscopic investigation on extracted premolar with dyschromia, related to the components of endodontic sealer.
    Rom J Morphol Embryol 2016 ;57(2):461-6
    Department of Endodontics, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania;
    The aim of this study was an assessment of the overall optical characteristics changes in volume of the dentin, after the diffusion of the chemical components included in the sealer throughout the endodontic space, in order to demonstrate the discoloration effect of the endodontic sealer on tooth crown of a recently extracted maxillary premolar. Thin sections were studied using the polarized transmitted light microscopy and under a stereomicroscope, operating in transmitted light and reflected light. There were performed serial images of magnitude 40×. Read More

    Effects of Preheated Composite on Micro leakage-An in-vitro Study.
    J Clin Diagn Res 2016 Jun 1;10(6):ZC36-8. Epub 2016 Jun 1.
    Reader, Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals , Chennai, India .
    Introduction: Resin composites have been the pinnacle of direct esthetic restorations ever since its discovery. However, it comes with its own disadvantages. Post-operative sensitivity and marginal discoloration frequently occur due to polymerization shrinkage and micro leakage, which is the major cause of failure in resin composite restorations. Read More

    1-year In Vitro Evaluation of Tooth Discoloration Induced by 2 Calcium Silicate-based Cements.
    J Endod 2016 Sep 3;42(9):1403-7. Epub 2016 Aug 3.
    Dentistry Department, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
    Introduction: The purpose of this study was to compare tooth discoloration that occurs in teeth filled with ProRoot MTA (DENTSPLY Tulsa Dental Specialties, Tulsa, OK) or Biodentine (Septodont, Saint Maur des Fossés, France) over the course of 1 year.

    Methods: Twenty-eight intact premolars were resected 2 mm apical to the cementoenamel junction and the pulp tissues extirpated via the cervical cut. After the preparation of occlusal access to the pulp chamber, specimens were assigned into 4 groups according to a stratified randomization sampling process: group 1, negative control (dry sterile cotton pellet); group 2, positive control (blood-moistened cotton pellet); group 3, ProRoot WMTA (DENTSPLY Tulsa Dental Specialties); and group 4, Biodentine. Read More

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