184,974 results match your criteria Tooth Discoloration


A Survey on the Prevalence and Risk Indicators of Erosive Tooth Wear among Adolescents in Guangzhou, South China.

J Oral Rehabil 2018 Dec 16. Epub 2018 Dec 16.

Southern Medical University, Savaid Medical School, University of the Chinese Academy of Sciences.

Background: Erosive tooth wear (ETW) has become a crucial oral health problem over the decades in China.

Objectives: To explore the prevalence and risk indicators of ETW among adolescents in Guangzhou, south China.

Methods: A cross-sectional survey of 720 participants was conducted in Guangzhou, using an equal-sized, stratified, multistage random sampling approach. Read More

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December 2018

Profiling of 54 plasma glycoproteins by label-free targeted LC-MS/MS.

Anal Biochem 2018 Dec 13. Epub 2018 Dec 13.

Centre for Analytical Bioscience, Advanced Materials and Healthcare Technologies Division, School of Pharmacy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. Electronic address:

Glycoproteins play a central role in diverse biological processes and are linked with many serious human diseases. In this paper we present a simple, reproducible and cost-effective analytical workflow that enables the reliable quantification of clinically relevant human plasma glycoproteins using label free microflow LC-MS/MS analysis. Plasma N-glycoproteins were selectively extracted via ConA Sepharose lectin affinity chromatography then separated into two fractions using reversed-phase solid phase extraction. Read More

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December 2018

Effect of radiotherapy on the chemical composition of root dentin.

Head Neck 2018 Dec 15. Epub 2018 Dec 15.

Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Background: The radiotherapy can directly affect the bond strength of the adhesive materials, interfering in the prognosis of restorative treatments, which may be caused by chemical changes in dentin structure.

Methods: Twenty inferior homologues premolars were distributed in 2 groups (in vitro study) (n = 10): nonirradiated and irradiated. The specimens were submitted to the analysis of phosphate (ν PO ;ν PO ;ν PO ), carbonate (ν CO ), amide I, CH , amide III, and amide I/III ratio by confocal Raman spectroscopy. Read More

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December 2018

Erosive wear of the primary dentition: who is aware of it?

Authors:
G Gatt N Attard

Eur Arch Paediatr Dent 2018 Dec 14. Epub 2018 Dec 14.

Faculty of Dental Surgery, University of Malta, Msida, Malta.

Aim: To determine the influence of erosive tooth wear in the primary dentition on parental perceptions of oral health.

Methods: This cross-sectional study involved a standardised clinical examination of 775 preschool aged children and a parent-administered questionnaire. Erosive tooth wear was measured using the Basic Erosive Wear Examination Index. Read More

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December 2018

Niche Partitioning in Theropod Dinosaurs: Diet and Habitat Preference in Predators from the Uppermost Cedar Mountain Formation (Utah, U.S.A.).

Sci Rep 2018 Dec 14;8(1):17872. Epub 2018 Dec 14.

Department of Biology, University of Oklahoma, Norman, Oklahoma, 73072, USA.

We explore hypothetical ecologies to explain diversity among predatory dinosaurs in North America's medial Cretaceous, based on occurrence, tooth morphology, and stable isotope analysis. The Mussentuchit local fauna, Utah, USA, is among the best-known terrestrial vertebrate assemblages from the Cretaceous. Study samples include teeth from six microvertebrate sites, ranging in depositional setting from distal floodplain to channel lags. Read More

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December 2018

Comparison of the Photosensitivity of Biofilms of Different Genera of Cariogenic Bacteria in Tooth Slices.

Pol J Microbiol 2018 ;67(4):455-462

Department of Physics, Faculty of Science and Arts, Jordan University of Science and Technology , Irbid , Jordan.

This study compared the outcome of photosensitization on the viability of four different cariogens in planktonic form as well as biofilms in human dentine. Photodynamic therapy was carried out with a gallium aluminium arsenide laser (670 nm wavelength) using Toluidine blue O (TBO) as the photosensitizer. Cariogenic bacteria ( Streptococcus mutans , Lactobacillus casei , Streptococcus salivarius and Actinomyces viscosus ) were exposed to TBO and then to the laser for 1 minute in planktonic suspension. Read More

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January 2018

Root dentinal microcracks: a post-extraction experimental phenomenon?

Int Endod J 2018 Dec 14. Epub 2018 Dec 14.

School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.

Aim: To investigate the prevalence, location, and pattern of preexisting microcracks in non-endodontically treated teeth from fresh cadavers. Micro-computed tomography (micro-CT) technology was used as the analytical tool enabling full screening of the root dentine with the teeth retained in their original alveolar socket.

Methodology: As a pilot study and to validate the present method, a series of 4 high-resolution scans were performed on one bone-block specimen with teeth collected postmortem: (i) entire bone-block including the teeth, (ii) second molar tooth extracted atraumatically from the bone-block (iii) extracted tooth dehydrated to induce dentinal defects and (iv) entire bone-block following reinsertion of the extracted tooth into its matching alveolar socket. Read More

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December 2018
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Beliefs about managing dental problems among older people and dental professionals in Southern Brazil.

Community Dent Oral Epidemiol 2018 Dec 13. Epub 2018 Dec 13.

Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada.

Objectives: To explore the sociocultural context in which patients and dentists in urban and rural communities in Southern Brazil interpret dental problems.

Method: Beliefs and experiences related to dental problems were explored in eight focus groups involving a total of 41 older patients, and in direct interviews with two dentists and two dental assistants. The interactions were audio recorded and transcribed for thematic analysis. Read More

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December 2018

The effect of diabetes on tooth loss due to periodontal disease: A nationwide population-based cohort study in south korea.

J Periodontol 2018 Dec 13. Epub 2018 Dec 13.

Department of Prosthodontics, National Health Insurance Service Ilsan Hospital, 100 Ilsan-ro, Ilsandong-gu, Goyang-si, , Gyeonggi-do, 10444, Republic of Korea.

Background: Our purpose was to compare the risk of tooth loss due to periodontal disease between diabetic and non-diabetic individuals and to estimate the relative risk of tooth loss according to the severity and control of diabetes.

Methods: We selected 10,215 individuals who diagnosed as diabetes in the Korean National Health Insurance Service - National Sample Cohort (NHIS-NSC) database in 2003 and the same number of individuals who had never been diagnosed with diabetes during the period covered by the NHIS-NSC (2002-2013) with propensity score matching. Diabetic individuals were divided into two groups according to the treatment modality. Read More

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December 2018

Neo-Marxian social class inequalities in oral health among the South Korean population.

Community Dent Oral Epidemiol 2018 Dec 13. Epub 2018 Dec 13.

Department of Preventive and Social Dentistry, Kyung Hee University, Seoul, Korea.

Aim: The aims of this study were to examine inequalities in periodontitis and tooth loss among South Korean adults using the Wright's Neo-Marxian social class (NMSC) indicator and to assess the impact of material, psychosocial, health behavioural and workplace environmental factors in the association of social class with oral health.

Methods: This study used the data from the 4th Korea National Health and Nutrition Examination Survey with 6710 participants aged 19-54 years old. Participants were classified into 12 social class positions based on the Wright's social class map. Read More

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December 2018

Mandibular osteotomy-induced hypoxia enhances osteoclast activation and acid secretion by increasing glycolysis.

J Cell Physiol 2018 Dec 12. Epub 2018 Dec 12.

Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Tongji University, Shanghai, China.

The rapid bone remodeling after osteotomy has been reported for a long time. However, the underlying mechanism promoting the active bone reconstruction was still to be elucidated. Since not only the bone, blood vessels, and supportive tissues, but also the local microenvironment were destroyed, if the changes on the cell metabolism was contributed to the accelerated bone remodeling came into sight. Read More

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December 2018

Buccal bone thickness at dental implants in the maxillary anterior region with large bony defects at time of immediate implant placement: A 1-year cohort study.

Clin Implant Dent Relat Res 2018 Dec 11. Epub 2018 Dec 11.

Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Background: There is lack of studies regarding preservation and possible changes in BBT at dental implants.

Purpose: To assess, on cone beam computer tomograms, the presence of bone at the time of tooth extraction in the maxillary esthetic region and the mean buccal bone thickness 1 month and 1 year after final restoration placement in patients with large bony defects.

Material And Methods: In a cohort study, patients were selected presenting a failing tooth with a large bony defect (test group [n = 20]: large bony defect, immediate placed implant and delayed provisionalization). Read More

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December 2018

The carious tooth.

Authors:
J Sinclair-Cohen

Br Dent J 2018 Dec;225(11):1001

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December 2018

Tooth or dare?

Br Dent J 2018 Dec;225(11):1001

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December 2018

Employment status of tooth fairies in doubt.

Authors:

Br Dent J 2018 Dec;225(11):997

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December 2018

Has doxycycline, in combination with anti-malarial drugs, a role to play in intermittent preventive treatment of Plasmodium falciparum malaria infection in pregnant women in Africa?

Malar J 2018 Dec 14;17(1):469. Epub 2018 Dec 14.

Unité Parasitologie et Entomologie, Département Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.

According to the World Health Organization (WHO), Plasmodium falciparum malaria during pregnancy is responsible for deleterious consequences for the mother and her child. The administration of intermittent preventive treatment (IPTp) with sulfadoxine-pyrimethamine (SP) at each antenatal care visit as early as 13 weeks of gestation until the time of delivery is a strategy that is currently recommended by WHO for the prevention of malaria in pregnancy. However, the emergence and the spread of the resistance to SP in Africa raise the question of the short-term effectiveness of the strategy. Read More

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December 2018

Effect of the application of high-frequency mechanical vibration on tooth length concurrent with orthodontic treatment using clear aligners: A retrospective study.

J Orthod Sci 2018 15;7:20. Epub 2018 Nov 15.

Division of Orthodontics, School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Objectives: To evaluate the possible change in teeth lengths as an indicator of orthodontically induced tooth root resorption (OITRR) after high-frequency mechanical vibration (HFV) treatment concurrent with Invisalign Smart Track® aligners as evaluated by cone beam computed tomography (CBCT).

Materials And Methods: The sample, composed of 30 patients with an average age of 26 ± 11 years and Class I malocclusion with an initial anterior crowding ranging from 3 to 5 mm, was divided equally into two groups; Group I received adjunctive high-frequency mechanical vibration (HFV); Group II, the control, did not receive adjunctive mechanical treatment. The maxillary incisor's teeth lengths were measured using Mimics software before (T1) and after (T2) treatment. Read More

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November 2018

Tramadol hydrochloride: An alternative to conventional local anaesthetics for intraoral procedures- a preliminary study.

J Oral Biol Craniofac Res 2019 Jan-Mar;9(1):111-114. Epub 2018 Nov 30.

Dept. of Public Health Dentistry at Yogita Dental College and Hospital, Khed, Ratnagiri, Maharashtra, India.

Purpose: To evaluate and compare the soft tissue anaesthesia produced by tramadol hydrochloride on gingival tissues in maxilla.

Methods: A total of 50 ASA physical status I subjects between 18 and 35 years of age, both male and female were included in the study. Each individual received 0. Read More

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November 2018
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A case of dental hamartoma associated with unerupted primary canine in maxillary region.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):232-234

Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.

Odontomas are usually one of the most common odontogenic tumors of the jaw and are perhaps more accurately defined as a hamartoma than a true neoplasm. It is asymptomatic, nonaggressive, slow growing, and benign nature. They are considered to be the malformations of the dental tissue and can sometimes interfere with the eruption of the associated tooth leading to its impaction or delayed eruption. Read More

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December 2018
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Comparative study on alveolar bone healing in postextraction socket versus healing aided with autologous platelet-rich fibrin following surgical removal of bilateral mandibular impacted third molar tooth: A radiographic evaluation.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):140-146

Department of Oral and Maxillofacial Surgery, Sri Ramakrishna Dental College and Hospital, Coimbatore, Tamil Nadu, India.

Aim: This study was to evaluate and compare the bone regeneration potential of autologous platelet-rich fibrin (PRF) placed in one of the extracted sockets after the surgical removal of bilateral impacted mandibular third molars.

Patients And Methods: Twenty-five patients (10 females and 15 males; 18-35 years old) were taken for surgical removal of bilateral impacted mandibular third molar, performed in the same session. The autologous PRF was placed in one of the extracted sockets whereas the opposite side was taken as control side, and primary closure was done. Read More

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December 2018

Combined endodontic therapy and peri-radicular regenerative surgery in the treatment of dens invaginatus type III associated with apicomarginal defect.

J Conserv Dent 2018 Nov-Dec;21(6):696-700

Private Practice, Noida, India.

Dens invaginatus (DI) is a dental developmental abnormality, probably resulting from an infolding of the dental papilla during tooth development. The following case report presents a case of Type III DI with apicomarginal defect and peri-radicular lesion, diagnosed with cone-beam computed tomography scan and treated with combined orthograde endodontic therapy and peri-radicular regenerative surgery. Follow-up examination at 2 years revealed uneventful healing and improvement in the status of the tooth-supporting structures. Read More

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December 2018
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Report of a case of platelet-rich fibrin-mediated revascularization of immature 12 with histopathological evaluation.

J Conserv Dent 2018 Nov-Dec;21(6):691-695

Department of Conservative Dentistry and Endodontics, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India.

The procedure of regeneration has shown promising results in the treatment of nonvital teeth with immature apices. However, the tissue being regenerated can only be confirmed through histological examination. This report describes an immature nonvital 12 with apical pathology which was treated via revascularization using 3% NaOCl and 17% ethylenediaminetetraacetic acid as irrigants; Ca(OH)2 as intracanal medicament and platelet-rich fibrin (PRF) as scaffold. Read More

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December 2018

Evaluation of remineralization potential and mechanical properties of pit and fissure sealants fortified with nano-hydroxyapatite and nano-amorphous calcium phosphate fillers: An study.

J Conserv Dent 2018 Nov-Dec;21(6):681-690

Department of Prosthodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Objectives: The aim of this study was: (i) to formulate pit and fissure sealants (PFS) containing nano-hydroxyapatite (nHAP) filler; nHAP filler and silica co-filler; nHAP and nano-Amorphous Calcium Phosphate (nACP) co-filler, (ii) to evaluate physical properties; degree of conversion (DOC), curing depth (CD) and mechanical properties; microshear bond strength (MBS) of fortified PFS, and (iii) to assess remineralization potential and release of Ca and PO ions from newly synthesized sealants.

Materials And Methods: Four PFS were prepared using monomers with mixture of 35.5 wt % BisGMA, 35. Read More

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December 2018

An appraisal of properties of dental amalgam using commercially available and ayurvedically recycled mercury: Recycle and reuse.

J Conserv Dent 2018 Nov-Dec;21(6):651-656

Department of Mechanical Engineering, IIT, BHU, Varanasi, Uttar Pradesh, India.

Introduction: With the introduction of tooth-colored restoration material, the usage of amalgam has reduced over years. However, results regarding toxicity and health concerns are conflicting. Based on the concept of recycle and reuse, we previously used an ayurvedic method for purification of excess mercury obtained from dental operatory. Read More

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December 2018

Clinical and Radiographic Evaluation of Early Loaded Maxillary Anterior Implants: Three-Year Follow-up.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):123-129

The aim of this study was to evaluate clinical and radiologic results up to 3 years in patients treated with early loading of anterior implants supporting single-tooth all-ceramic restorations. Twenty-four patients were treated with 29 screw-type implants in the anterior maxilla. The implants were evaluated by clinical and radiographic parameters. Read More

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December 2018

Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Fibrin Glue for Periodontal Regeneration.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):e32-e45

Appropriate regeneration of periodontal tissues is the primary purpose of periodontal disease treatment. The present study assessed the impact of three key regenerative elements-platelet-rich plasma (PRP), canine bone marrow mesenchymal stem cells (cBM-MSCs), and fibrin glue-on periodontal regeneration. In each of the study's five dogs, Class II furcation defects were established on the buccal surface of five teeth. Read More

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December 2018
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Facial Esthetic Considerations with All-on-4: A Report on Two Cases.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):57-64

This article describes two case reports of immediate full-arch dental implant- supported prostheses using facial parameters to determine the anticipated incisal edge (AIE) position. Treatment planning the terminal dentition is driven by several facial parameters. A frontal photo is obtained to assess the facial thirds and the symmetry in the lower third. Read More

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December 2018

Randomized Controlled Clinical Trial of All-Ceramic Single-Tooth Implant Reconstructions Using Modified Zirconia Abutments: Results at 5 Years After Loading.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):17-27

The objective of this trial study was to assess whether submucosal veneering of internally connected zirconia abutments influences clinical, radiographic, and technical outcomes of single-tooth implant-borne reconstructions at 5 years after loading. A total of 20 patients with 20 single-tooth implants in the anterior or premolar area of the maxilla or mandible were included. The implants were randomly restored with fixed single-tooth reconstructions using either pink-veneered customized zirconia abutments (test group = 10) or nonveneered customized zirconia abutments (control group = 10). Read More

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December 2018

[Evaluation of supplemental and oral deglutition foods in bedridden elderly patients receiving parenteral nutrition].

Nihon Ronen Igakkai Zasshi 2018 ;55(4):594-604

Department of Physical Medicine and Rehabilitation, Yokohama City University Medical Faculty.

Background And Aim: We examined oral dyskinesia (OD), wearing artificial tooth, food test findings and conducted a video - fluoroscopic swallowing study (VFSS) in bedridden elderly patients before they were received parenteral nutrition once daily. However, the validity and properties of these deglutition foods have not been evaluated. Therefore, in this study, we clarified four deglutition foods as four aspects. Read More

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January 2018

Wear properties of esthetic dental materials against translucent zirconia.

Dent Mater J 2018 Dec 11. Epub 2018 Dec 11.

Department of Oral and Maxillofacial Implantology, Tokyo Dental College.

To clarify the influence of translucent tetragonal zirconia polycrystals (TZP) on wear properties of esthetic dental materials, twobody wear test was performed using translucent TZP as abrader specimen, and bovine tooth enamel (BTE), two resin composites including hybrid filler (CRH) and nano filler (CRN), two glass ceramics including leucite reinforced feldspar porcelain (POR) and lithium disilicate (LDC), or translucent TZP as substrate specimen. After the wear test, wear volume were determined from substrate specimen and surface roughness were measured from abrader specimen. In addition, Vickers hardness was measured and surface morphologies were observed after wear test using a scanning electron microscope. Read More

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December 2018

Effects of pastes containing ion-releasing particles on dentin remineralization.

Dent Mater J 2018 Dec 11. Epub 2018 Dec 11.

Division of Orthodontics and Dentofacial Orthopedics, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido.

We investigated the effects of the weekly application of pastes containing a surface reaction-type pre-reacted glass-ionomer (S-PRG) filler on dentin remineralization. Human dentin blocks were demineralized and polished using pastes containing S-PRG filler (0, 5, and 30%), and then immersed in remineralizing solution for 1 month. Nanoindentation testing was carried out during the immersion period, and the dentin surfaces were examined using scanning electron microscopy. Read More

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December 2018

Measurement of hepatitis B virus DNA in fresh versus processed dentin from chronically infected patients.

J Transl Med 2018 Dec 12;16(1):351. Epub 2018 Dec 12.

Dental Life Science Research Institute/Clinical Translational Research Center for Dental Science, Seoul National University Dental Hospital, 101 Daehark-ro, Jongno-gu, Seoul, 03080, South Korea.

Background: Demineralized dentin matrix (DDM) is commonly used as a bone-graft substitute. This study measured and compared human hepatitis B viruses (HBV) DNA in fresh dentin to that of dentin processed into DDM extracted during dental treatment from HBV-infected patients. The hypothesis was that the processing procedure for DDM would inactivate or eliminate HBV in the dentin matrix obtained from infected patients. Read More

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December 2018

[Mothers’ responses to teething in children in Ferlo, Senegal].

Sante Publique 2018 May June;30(3):405-410

Introduction: Tooth eruption is a process that begins in infancy and continues throughout childhood and adolescence. This complex phenomenon induces systemic disorders requiring specific management. The objective of this study was to identify the therapeutic responses to teething in children in Ferlo, Senegal. Read More

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December 2018

[Teaching tooth brushing to children with autistic spectrum disorder : A tablet-based training programme.]

Sante Publique 2018 May June;30(3):297-306

Objective: The primary objective of this exploratory study was to evaluate the short-term (four months) impact of a tooth brushing learning programme based on pictograms generated by the çATED app for iPad designed for patients with autistic spectrum disorder (ASD).

Methods: Fifty-two ASD patients, between the ages of 3 and 19 years, from seven educational centres, were included. A tooth brushing training programme was proposed in collaboration with the educational teams. Read More

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December 2018

Periodontal regeneration with autologous periodontal ligament-derived cell sheets - A safety and efficacy study in ten patients.

Regen Ther 2018 Dec 24;9:38-44. Epub 2018 Aug 24.

Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.

Background: Periodontitis results in the destruction of tooth-supporting periodontal tissues and does not have the ability to heal spontaneously. Various approaches have been introduced to regenerate periodontal tissues; however, these approaches have limited efficacy for treating severe defects. Cytotherapies combine stem cell biology and tissue engineering to form a promising approach for overcoming these limitations. Read More

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December 2018

Oral Health Impact Profile and Associated Variables in Southern Brazilian Drug Users.

Iran J Public Health 2018 Oct;47(10):1466-1475

Dept. of Dentistry, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.

Background: This study investigated the association between sociodemographic, behavioral, oral health, variables of drug consumption, and the short version of the Oral Health Impact Profile (OHIP-14), in Southern Brazilian drug users.

Methods: In this cross-sectional study, 202 drug users aged 18 or over admitted for treatment at the Institute for Research and Treatment of Alcoholism ( -IPTA) from the municipality of Campo Largo, PR, Brazil, from 2012 to 2014, were involved. They answered a questionnaire and were examined by a calibrated researcher. Read More

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October 2018
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Interleukin-18 expression in oral squamous cell carcinoma: its role in tumor cell migration and invasion, and growth of tumor cell xenografts.

FEBS Open Bio 2018 Dec 31;8(12):1953-1963. Epub 2018 Oct 31.

Department of Oral and Maxillofacial Surgery School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.

Oral squamous cell carcinoma (OSCC) is one of the most common head and neck malignancies. Advanced stages of the disease are associated with poor survival, highlighting a need for new treatment modalities. We previously showed that the proinflammatory cytokine interleukin-18 (IL-18) has a tumor suppressive role in OSCC. Read More

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December 2018

Tooth Repair and Regeneration.

Curr Oral Health Rep 2018 25;5(4):295-303. Epub 2018 Oct 25.

1Centre for Craniofacial and Regenerative Biology, Dental Institute, King's College London, London, UK.

Purpose Of Review: Current dental treatments are based on conservative approaches, using inorganic materials and appliances.This report explores and discusses the newest achievements in the field of "regenerative dentistry," based on the concept of biological repair as an alternative to the current conservative approach.

Recent Findings: The review covers and critically analyzes three main approaches of tooth repair: the re-mineralization of the enamel, the biological repair of dentin, and whole tooth engineering. Read More

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October 2018

Reparative Dentistry: Possibilities and Limitations.

Curr Oral Health Rep 2018 15;5(4):264-269. Epub 2018 Sep 15.

2Division of Dental Materials, Center for Dental and Oral Medicine, Clinic for Fixed and Removable Prosthodontics and Dental Materials Science, University of Zurich, Zurich, Switzerland.

Purpose Of Review: Defective dental restorations are amongst the most common encounters in general dental practice. Replacement of defective restorations is often costly and commonly results in the sacrifice of sound tooth structure, thereby compromising the vitality of the dental pulp, potentially resulting in the acceleration of the restoration cycle and premature loss of the restored tooth. With advances in adhesive dentistry, 'reparative dentistry' is becoming an important area of minimally invasive dentistry. Read More

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September 2018

assessment of alendronate toxic and apoptotic effects on human dental pulp stem cells.

Iran J Basic Med Sci 2018 Sep;21(9):905-910

Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Objectives: Osteonecrosis of the jaw, as an exposed necrotic bone in the oral cavity, is one of the adverse effects of bisphosphonates, which have an affinity for bone minerals. This study investigates the cytotoxic effects of alendronate (ALN) as a nitrogen-containing bisphosphonate, on human dental pulp stem cells (hDPSCs).

Materials And Methods: The mesenchymal stem cells (MSCs), obtained from third molar tooth pulps were characterized by immunophenotyping assay in order to identify surface markers to evaluate their expression. Read More

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September 2018
2 Reads

DLX3 Inhibits the Proliferation of Human Dental Pulp Cells Through Inactivation of Canonical Wnt/β-Catenin Signaling Pathway.

Front Physiol 2018 20;9:1637. Epub 2018 Nov 20.

The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.

Homeodomain gene () plays an important role during tooth development. Our previous studies indicate that DLX3 inhibits proliferation of human dental pulp cells (hDPCs). However, the mechanism of DLX3 regulating proliferation of hDPCs and maintaining the quiescence of the cells remain unknown. Read More

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November 2018

Accurate tooth segmentation with improved hybrid active contour model.

Phys Med Biol 2018 Nov 27. Epub 2018 Nov 27.

Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, CHINA.

In orthodontic diagnosis and oral treatment planning, 3D tooth model constructed by dental computed tomography (CT) images is an essential and useful assisted tool. In virtue of the higher spatial resolution and lower radiation of X-ray, cone beam computed tomography (CBCT) has been widely used in dental application. However, due to lower signal to noise ratio, vague and weak edge between tooth root and sockets as well as intensity inhomogeneity, the tooth root is easy to be under- segmented and appears false boundary. Read More

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November 2018

Prominin-1 controls stem cell activation by orchestrating ciliary dynamics.

EMBO J 2018 Dec 6. Epub 2018 Dec 6.

Peninsula Dental School, University of Plymouth, Plymouth, UK

Proper temporal and spatial activation of stem cells relies on highly coordinated cell signaling. The primary cilium is the sensory organelle that is responsible for transmitting extracellular signals into a cell. Primary cilium size, architecture, and assembly-disassembly dynamics are under rigid cell cycle-dependent control. Read More

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December 2018

Modified maxillary vestibular approach with subperiostal intranasal dissection for surgical extractions of mesiodentes impacted in the floor of the nasal cavity.

J Craniomaxillofac Surg 2018 May 18. Epub 2018 May 18.

Department of Oral and Maxillofacial Surgery (Head of Department: Dr. Daniel Hrusak, Ph.D.), University Hospital and Faculty of Medicine in Pilsen, Charles University in Prague, AlejSvobody 80, 304 60 Pilsen, Czech Republic.

Introduction: Impacted mesiodentes in the inverted position may interfere with the base of the nasal cavity or the nasal septum. They can rarely erupt into the nose as well. Traditionally they are extracted via intraoral approaches (transpalatal or vestibular). Read More

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Biomimetic transformation of polyphosphate microparticles during restoration of damaged teeth.

Dent Mater 2018 Dec 3. Epub 2018 Dec 3.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany. Electronic address:

Objective: In the present study, we investigated the fusion process between amorphous microparticles of the calcium salt of the physiological polymer comprising orthophosphate units, of inorganic polyphosphate (polyP), and enamel.

Methods: This polymer was incorporated as an ingredient into toothpaste and the fusion process was studied by electron microscopy and by synchrotron-based X-ray tomography microscopy (SRXTM) techniques.

Results: The data showed that toothpaste, supplemented with the amorphous Ca-polyP microparticles (aCa-polyP-MP), not only reseals tooth defects on enamel, like carious lesions, and dentin, including exposed dentinal tubules, but also has the potential to induce re-mineralization in the enamel and dentin regions. Read More

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December 2018
3.769 Impact Factor

[Research progress in the application of implantoplasty in the treatment of peri-implantitis].

Authors:
H Y Lai W Wang X H Gu

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Dec;53(12):854-857

Department of Prosthodontics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Peri-implantitis is a kind of serious complication after tooth implantation. The absorption of alveolar bone lead to the exposure of rough implant surface, which would result in poor long-term therapeutic effect. Implantoplasty promises a better long-term therapeutic effect than bone augmentation technique. Read More

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December 2018

[Aesthetic complications of immediate implant placement of anterior teeth].

Authors:
B Shi

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Dec;53(12):810-814

Department of Dental Implantology, School of Stomatology, Wuhan University, Wuhan 430072, China.

In the anterior tooth zone, the criteria of successful implant restoration is not only to ensure a high survival rate of implant, but also to provide long-lasting and stable aesthetic outcomes. As for the rehabilitation of anterior teeth, immediate implant placement might achieve a survival rate similar to those of delayed implant placement and significantly reduce treatment time, whereas several aesthetic complications such as gingival recession, loss of interdental papilla, exposure of implant margin could also occur. Therefore, an important issue need to be solved is that how to avoid or handle the aesthetic complications of immediate implant placement of anterior teeth. Read More

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December 2018

[Role of occlusion in complications of implant rehabilitation].

Authors:
P Gong

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Dec;53(12):800-804

Department of Dental Implantology, West China Hospital of Stomatology, Sichuan University & State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Chengdu 610041, China.

Peri-implantitis, restoration loosening and fracture, implant structural damage are common post-restorative complications in implant rehabilitation. With an increasing incidence, they may occur in implant-supported single or splinted crowns, bridges, overdenture or fixed denture. Possible causes involve not only the design of implant components structure and characteristics of restorative materials, but also the design of restoration and the occlusal function and structure of patients. Read More

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December 2018

[Risk factors, diagnosis and treatment of peri-implant diseases].

Authors:
Z Fan Z L Wang

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Dec;53(12):793-799

Department of Dental Implantology, School of Stomatology, Tongji University & Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, China.

With the wide spread of dental implantation, more and more soft and hard tissue illness related to dental implants occurred. According to a statistical analysis, about 1/4 to 1/2 patients are under the risk of suffering from peri-implant diseases. Peri-implant diseases include peri-implant mucotitis and peri-implantitis. Read More

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December 2018

Acutely infected teeth: to extract or not to extract?

Braz Oral Res 2018 Dec 6;32:e124. Epub 2018 Dec 6.

Necmettin Erbakan University, Faculty of Dentistry, Oral and Maxillofacial Surgery Department, Konya, Turkey.

Not only laymen but also dentists generally believe that extraction of acutely infected teeth should be avoided until the infection subdues by using systemic antibiotics. The aim of this study was to compare perioperative complications in routine extractions of acutely infected teeth with extractions of asymptomatic teeth. This prospective study was performed with 82 patients. Read More

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December 2018
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