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    Pulpal and Periodontal Tissues Changes Associated with Le Fort I and Sagittal Split Ramus Osteotomies: A review.
    Open Dent J 2018 29;12:24-31. Epub 2018 Jan 29.
    Department of Orthodontics, Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
    Introduction: Le Fort I and sagittal split ramus osteotomies are the most commonly performed orthognathic surgery procedures on the maxilla and mandible, respectively.

    Techniques: Despite progress in the techniques, these procedures may still be associated with morbidity, expressed as inflammation, inadequate bony union, periodontal damages or in extreme cases even total bone loss.

    Discussion: Through a comprehensive review of the literature, the influences of maxillary and mandibular surgery on Pulpal Blood Flow (PBF), pulp sensitivity and pulp vitality are examined. Read More

    Single-Tooth Replacement Using Dental Implants Supporting All-Ceramic and Metal-Based Reconstructions: Results at 18 Months of Loading.
    Int J Periodontics Restorative Dent 2018 Mar/Apr;38(2):173-179
    The aim of this study was to compare customized zirconia and titanium abutments with respect to survival rates and technical, biologic, and esthetic outcomes. A total of 28 patients with single implants were randomly assigned to 12 customized zirconia (test, AC) and 16 customized titanium (control, MC) abutments. Technical, biologic, and esthetic outcomes were assessed after a mean follow-up time of 18 months. Read More

    Effect of ultrasonic activation of photosensitizer dye temoporfin (Foscan) on antimicrobial photodynamic therapy: Anstudy.
    J Conserv Dent 2017 Nov-Dec;20(6):419-423
    Department of Conservative and Endodontics, St. Joseph Dental College, Eluru, Andhra Pradesh, India.
    Aim: The aim of this study is to evaluate the effectiveness of ultrasonic activation of photosensitizer (PS) drug Foscan in the elimination of endodontic pathogen from root canal system.

    Materials And Methods: The minimal bactericidal concentration of "Foscan" was determined using disc diffusion and broth dilution method. Forty-eight extracted single-rooted premolars with periapical pathology were used for the study. Read More

    Effect of incorporation of a new antimicrobial nanomaterial on the physical-chemical properties of endodontic sealers.
    J Conserv Dent 2017 Nov-Dec;20(6):392-397
    Department of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, São Paulo, Brazil.
    Objectives: The objective of the study is to incorporate the nanostructured silver vanadate (AgVO) decorated with silver nanoparticles at endodontic sealers AH Plus, Sealapex, Sealer 26, and Endofill, at concentrations of 2.5%, 5%, and 10%, and to evaluate physical-chemical properties.

    Materials And Methods: The study was to evaluate the radiopacity using digital radiography (= 5), the tooth color change in 48 incisors (= 3) for 7, 30, 90, and 180 days in a spectrophotometer, and the topographic distribution in a confocal laser (= 5). Read More

    The Discoloration effect of White Mineral Trioxide Aggregate (WMTA), Calcium Enriched Mixture (CEM), and Portland Cement (PC) on Human Teeth.
    J Clin Exp Dent 2017 Dec 1;9(12):e1397-e1401. Epub 2017 Dec 1.
    Associate Professor of Biostatistics, Department of Statistics and Epidemiology, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran.
    Background: The aim of this study was to evaluate the discoloration induced by CEM cement, Portland cement (PC) and MTA mixed with propylene glycol (MTA-PG) in comparison to White MTA.

    Material And Methods: Ninety extracted premolar and canine teeth were resected 2 mm below the CEJ. The coronal part of crown was prepared with peeso reamer and Gates-Glidden drills, and the specimens were randomly divided into 4 experimental (n=20) and one control (n=10) groups. Read More

    Outcomes of Direct Pulp Capping by Using Either ProRoot Mineral Trioxide Aggregate or Biodentine in Permanent Teeth with Carious Pulp Exposure in 6- to 18-Year-Old Patients: A Randomized Controlled Trial.
    J Endod 2017 Dec 21. Epub 2017 Dec 21.
    Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand. Electronic address:
    Introduction: This study aimed to compare the success rates of direct pulp capping (DPC) by using either ProRoot Mineral Trioxide Aggregate (MTA) or Biodentine in the cariously exposed permanent teeth of 6- to 18-year-old patients. Gray discoloration was also evaluated.

    Methods: Fifty-nine cariously exposed permanent teeth, including teeth with diagnosis of normal pulp, reversible pulpitis, or irreversible pulpitis, early periapical involvement, and exposure size of up to 2. Read More

    Spectrophotometric analysis of coronal discoloration induced by white mineral trioxide aggregate and Biodentine: Anstudy.
    J Conserv Dent 2017 Jul-Aug;20(4):237-240
    Department of Conservative Dentistry and Endodontics, KMCT Dental College, Kozhikode, Kerala, India.
    Aims: The aim of this study was to evaluate the specific chromatic alterations in tooth crowns induced by two different endodontic restorative materials.

    Settings And Design: Thisstudy was conducted at the Department of Conservative Dentistry, KMCT Dental College, Kozhikode, Kerala.

    Subjects And Methods: Forty-five freshly extracted, fully developed, single-rooted teeth were prepared and randomly assigned to two experimental groups (= 15 each) and one negative control group (= 15). Read More

    Genotoxicity, Bioactivity and Clinical Properties of Calcium Silicate Based Sealers: A Literature Review.
    Iran Endod J 2017 ;12(4):407-413
    Department of Operative Dentistry, Dental School, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
    An ideal endodontic sealer should have many properties such as excellent seal after setting, dimensional stability, slow setting time to ensure sufficient working time, insolubility to tissue fluids, adequate adhesion with canal walls and biocompatibility. Genotoxicity is one of the important factors that influence biocompatibility of an endodontic sealer. This literature review was conducted to survey the genotoxicity, bioactivity and clinical perspectives of calcium silicate based sealers. Read More

    Spectrophotometric Evaluation of Crown Fragment a Year After Reattachment Using Fiber-Reinforced Post: A Case Report.
    Ethiop J Health Sci 2017 Sep;27(5):565-569
    Department of Prosthodontics, Faculty of Dentistry, Ordu University, Ordu, Turkey.
    Background: Crown fracture is the most common type of fracture and frequently affects the anterior teeth. Crown fractures have been treated in several ways depending on the location and kind of fracture. This case emphasizes reattachment of fractured fragments using fiber-reinforced post. Read More

    Effect of different resin luting cements on the marginal fit of lithium disilicate pressed crowns.
    J Prosthet Dent 2017 Nov 15. Epub 2017 Nov 15.
    Research Associate, Institute of Dentistry and Oral Sciences, Palacky University, Olomouc, Czech Republic. Electronic address:
    Statement Of Problem: The vertical marginal discrepancy of restorations can increase upon cementation, and poor marginal fit can lead to cement dissolution, marginal discoloration, microleakage, and secondary caries. The amount of increase is related to the type of luting cement used, but how lithium disilicate pressed crowns are affected by different resin cements is unclear.

    Purpose: The purpose of this in vitro study was to compare the effect of using different resin luting cements on the vertical marginal discrepancy of lithium disilicate pressed crowns. Read More

    Effectiveness and Impact of the Walking Bleach Technique on Esthetic Self-perception and Psychosocial Factors: A Randomized Double-blind Clinical Trial.
    Oper Dent 2017 Nov/Dec;42(6):596-605
    Objective: This trial evaluates the impact of psychosocial and esthetic self-perceptions of patients undergoing nonvital tooth bleaching using the walking bleach technique. We also assessed the clinical effectiveness of bleaching tooth discoloration.

    Methods: Fifty volunteers with nonvital tooth discoloration were enrolled. Read More

    Risk Factors Associated with Black Tooth Stain
    Acta Clin Croat 2017 03;56(1):28-35
    Žaja Private Dental Practice, Zagreb, Croatia
    The aim of the study was to show whether there is any influence of food, drink or drug intake on the formation of tooth discoloration. A total of 500 patients aged 15-25 years were examined to take part in the study. Of these, 60 patients were selected and divided into two groups of 30 patients each. Read More

    Prevention of coronal discoloration induced by regenerative endodontic treatment in an ex vivo model.
    Clin Oral Investig 2017 Oct 31. Epub 2017 Oct 31.
    School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, 5 Mill Pool Way, Edgbaston, Birmingham, B5 7EG, UK.
    Objectives: The aim of this study was to assess the effect of sealing the pulp chamber walls with a dentin-bonding agent (DBA) on prevention of discoloration induced by regenerative endodontic procedures (REPs) in an ex vivo model.

    Materials And Methods: Ninety-six bovine incisors were prepared and randomly divided into two groups. In one group, the pulp chamber walls were sealed with DBA before placement of triple antibiotic paste (TAP) containing minocycline inside the root canals, but in the other group, DBA was not applied. Read More

    Bleaching of a Discolored Tooth with Retrieval of Remnants after Successful Regenerative Endodontics.
    J Endod 2018 Jan 24;44(1):93-97. Epub 2017 Oct 24.
    Melbourne Dental School, University of Melbourne, Melbourne, Victoria, Australia. Electronic address:
    Introduction: This report presents the retrieval of remnants from a discolored mandibular right second premolar (tooth #29) of a 17-year-old female after a successful regenerative endodontic procedure (REP).

    Methods: The REP was performed in October 2011. Coronal discoloration became of great concern to the patient at a review visit in 2016. Read More

    Stain removal and whitening by baking soda dentifrice: A review of literature.
    J Am Dent Assoc 2017 Nov;148(11S):S20-S26
    Background: Tooth discoloration may be caused by intrinsic or extrinsic stains or a combination of both. There are 2 major approaches to removing the stains, including the chemical mechanism using peroxides for tooth bleaching and the mechanical mechanism using abrasives in prophylactic pastes and dentifrices to remove stains, resulting in a whitening effect. Attempts have also been made to add a low concentration of peroxides to dentifrices to enhance their abrasive cleaning to remove tooth stains. Read More

    [Medicaments and oral healthcare 5. Adverse effects of -medications and over-the-counter drugs on teeth].
    Ned Tijdschr Tandheelkd 2017 Oct;124(10):485-491
    Intrinsic tooth discoloration may occur as an adverse effect of fluoride and tetracyclines. Extrinsic tooth discoloration may occur as superficial staining or as discoloration of the superficial pellicle and/or biofilm due to chlorhexidine, liquid iron salts, essential oils, some antibiotics and stannous fluoride. Inhibition of orthodontic tooth movement has been reported due to the use of prostaglandin synthetase inhibitors. Read More

    The micromorphological characterization of adhesive bond in dentin different locations.
    Microsc Res Tech 2018 Jan 7;81(1):33-37. Epub 2017 Oct 7.
    Faculty of Medicine, Department of Dentistry, University of Novi Sad, Novi Sad, Serbia.
    The aim of this study was to analyse the interfacial micromorphology of total-etch adhesives and dentin structures different locations by using SEM. Standardized cylindrical cavities (3mm in diameter, 2mm deep) with all margins in dentin were prepared on occlusal and buccal surfaces of twenty extracted human third molars. A total-etch dentin adhesive system and a light-cure flowable composite (Filtek Ultimate Flowable, 3M ESPE, St. Read More

    Pulp Calcification in Traumatized Primary Teeth - Classification, Clinical And Radiographic Aspects.
    J Clin Pediatr Dent 2017;41(6):467-471. Epub 2017 Sep 22.
    Objective: The aim of this study was to standardize the nomenclature of pulp alteration to pulp calcification (PC) and to classify it according to type, quantity and location, as well as relate it to clinical and radiographic features.

    Study Design: The dental records of 946 patients from the Research and Clinical Center for Dental Trauma in Primary Teeth were studied. Two hundred and fifty PC-traumatized upper deciduous incisors were detected. Read More

    Retrospective clinical evaluation of ceramic onlays placed by dental students.
    J Prosthet Dent 2017 Sep 16. Epub 2017 Sep 16.
    Associate Professor, Department of Restorative Dentistry, Schulich Medicine and Dentistry, Western University, London, Ontario, Canada. Electronic address:
    Statement Of Problem: Indirect restorations with partial or complete occlusal surface coverage have been recommended to restore teeth with weakened walls in order to prevent cusp fracture. The success of these restorations when performed by dental students is unknown.

    Purpose: The purpose of this retrospective study was to evaluate the clinical performance of adhesively bonded ceramic onlay restorations placed by third- and fourth-year dental students. Read More

    Tooth Discoloration Induced by Different Calcium Silicate-based Cements: A Systematic Review of In Vitro Studies.
    J Endod 2017 Oct 30;43(10):1593-1601. Epub 2017 Aug 30.
    Department of Conservative Dentistry and Endodontics, Pomeranian Medical University in Szczecin, Szczecin, Poland.
    Introduction: On the basis of many clinical observations, some calcium silicate-based cements have a high potential for staining tooth tissue. This feature greatly limits the use of those cements, particularly for anterior teeth. This review aimed to provide a systematic evaluation of published in vitro studies to determine the effect of different calcium silicate-based cements on dental tissue discoloration. Read More

    Lakartidningen 2017 Aug 23;114. Epub 2017 Aug 23.
    Drotting Silvias Barn- och Ungdomssjukhus - Barnmedicin Göteborg, Sweden -.
    Doxycycline can be given to children without risk of staining of teeth In Sweden, several hundred children are treated for Lyme neuroborreliosis annually, the majority of which are treated with intravenous ceftriaxone. Older tetracycline class antibiotics can cause permanent staining of the teeth. For doxycycline this has never been shown. Read More

    Spectrophotometric analysis of crown discoloration following the use of silver nanoparticles combined with calcium hydroxide as intracanal medicament.
    J Clin Exp Dent 2017 Jul 1;9(7):e842-e847. Epub 2017 Jul 1.
    PhD, Color Imaging and Color Image Processing Department, Institute for Color Science and Technology (ICST), Tehran, Iran.
    Background: Optimal antibacterial efficacy of intracanal medicaments containing silver nanoparticles (Ag-NPs) has been well documented. However, concerns remain regarding the effect of Ag-NPs on tooth color. This study aimed to assess the effects of calcium hydroxide (CH) mixed with Ag-NPs as intracanal medicaments on tooth color. Read More

    Oral health literacy and oral health outcomes in an adult population in Brazil.
    BMC Public Health 2017 07 26;18(1):60. Epub 2017 Jul 26.
    Department of Community Dentistry, Piracicaba Dental School, University of Campinas, Brazil, Avenida Limeira 901, P.O. Box 52, Piracicaba, SP, 13414-018, Brazil.
    Background: To investigate the association between critical and communicative oral health literacy (OHL) and oral health outcomes (status, oral health-related quality of life and practices) in adults.

    Methods: This cross-sectional study examined a household probability sample of 248 adults, representing 149,635 residents (20-64 years old) in Piracicaba-SP, Brazil. Clinical oral health and socioeconomic and demographic data, as well as data on oral health-related quality of life (OHIP-14) and health practices were collected. Read More

    Ten-Year Follow-Up of a Fragment Reattachment to an Anterior Tooth: A Conservative Approach.
    Case Rep Dent 2017 27;2017:2106245. Epub 2017 Jun 27.
    Department of Prosthetic Dentistry, Federal Fluminense University, Health Institute of Nova Friburgo, School of Dentistry, Rua Doutor Silvio Henrique Braune 22, 28625-650 Nova Friburgo, RJ, Brazil.
    This report describes the 10-year follow-up data of a patient who underwent fragment reattachment to the maxillary central incisor after coronal fracture with pulp exposure as well as the procedures followed for functional and esthetic adjustments. A 9-year-old female patient presented at the clinic of dentistry at the State University of Rio de Janeiro with a coronal fracture and pulp exposure of the right maxillary central incisor that had occurred immediately after an accident. The intact tooth fragment was recovered at the accident site and stored in milk. Read More

    Attitudes of Greek dentists towards repair of conservative restorations. An online survey.
    Int Dent J 2017 Dec 23;67(6):351-359. Epub 2017 Jul 23.
    Department of Operative Dentistry, Dental School, National and Kapodistrian University of Athens, Athens, Greece.
    Objectives: Repair versus replacement of a defective direct restoration is one important step for conserving tooth structure. This study was designed to collect information on the attitudes of Greek dentists towards repairing direct restorations.

    Methods: An electronic questionnaire with 16 multiple-choice and rank-ordering questions was created online and its URL address was randomly emailed to 800 dentists in the area of Athens, Greece. Read More

    Long-term in-vivo effect of various restorative materials on enamel and dentin of primary molars.
    Quintessence Int 2017 ;48(8):633-638
    Objective: To explore the long-term in-vivo effect of different dental restorative materials on the surrounding enamel and dentin, in primary molars.

    Method And Materials: Sixteen naturally exfoliated primary molars restored with amalgam, compomer, and glass-ionomer cement were collected after 2 to 5 years of function in the mouth. Four intact molars served as control. Read More

    Thirty-Six-Month Clinical Comparison of Bulk Fill and Nanofill Composite Restorations.
    Oper Dent 2017 Sep/Oct;42(5):478-485. Epub 2017 Jun 5.
    Objectives: The aim of this study was to evaluate the clinical performance of a nanofill and a bulk fill resin composite in class II restorations.

    Methods And Materials: In accordance with a split-mouth design, 50 patients received at least one pair of restorations, restored with a nanofill resin composite (Filtek Ultimate [FU]) and with a bulk fill resin composite (Tetric EvoCeram Bulk Fill [TB]). Each restorative resin was used with its respective adhesive system according to the manufacturers' instructions. Read More

    Whitening dentifrice and tooth surface discoloration-a systematic review and meta-analysis.
    Int J Dent Hyg 2018 Feb 2;16(1):24-35. Epub 2017 Jun 2.
    Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
    Objective: The aim of this systematic review was to assess the effect of a whitening dentifrice (WDF) relative to a regular dentifrice (RDF) on the reduction of natural extrinsic tooth surface discoloration (ETD).

    Materials And Methods: The MEDLINE-PubMed, Cochrane-CENTRAL and EBSCO-Dentistry and Oral Sciences databases were searched, up to April 2017. The inclusion criteria were as follows:(randomized)controlled clinical trials, healthy subjects ≥18 years of age, studies comparing WDF with RDF, a follow-up period of at least 6 weeks and studies scoring ETD as the stain area/extent, stain intensity or a composite score. Read More

    Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis.
    N Engl J Med 2017 06;376(22):2122-2133
    From the Cumming School of Medicine and the Hotchkiss Brain Institute, Calgary, AB (L.M.M., G.C., J.G., M.Y., M.D.H., V.W.Y.), the University of British Columbia, Vancouver (D.K.B.L., A.L.T., A.R.), the University of Montreal, Montreal (P.D.), Western University, London, ON (M.K.), Fraser Health MS Clinic, Burnaby, BC (G.V.), the University of Ottawa and the Ottawa Hospital Research Institute, Ottawa (M.S.F.), Dalhousie University, Halifax, NS (V.B.), the University of Alberta, Edmonton (G.B.), the University of Manitoba, Winnipeg (J.J.M.), Clinique Neuro Rive-Sud, Greenfield Park, QC (F.G.), the University of Toronto, Toronto (L.L.), and CHA-Hôpital Enfant-Jésus, Quebec, QC (M.T.) - all in Canada; and Tufts University, Boston (M.E.).
    Background: On the basis of encouraging preliminary results, we conducted a randomized, controlled trial to determine whether minocycline reduces the risk of conversion from a first demyelinating event (also known as a clinically isolated syndrome) to multiple sclerosis.

    Methods: During the period from January 2009 through July 2013, we randomly assigned participants who had had their first demyelinating symptoms within the previous 180 days to receive either 100 mg of minocycline, administered orally twice daily, or placebo. Administration of minocycline or placebo was continued until a diagnosis of multiple sclerosis was established or until 24 months after randomization, whichever came first. Read More

    The effect of a tooth/tongue gel and mouthwash regimen on morning oral malodour: A 3-week single-blind randomized clinical trial.
    Int J Dent Hyg 2018 Feb 24;16(1):92-102. Epub 2017 May 24.
    Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands.
    Aim: To compare the effects of a regimen consisting of a tooth/tongue gel, tongue cleaner and mouthwash with the effects of using standard fluoride dentifrice on the organoleptic oral malodour score (ORG) and volatile sulphur compounds (VSCs).

    Materials And Methods: A total, 66 non-dental students participated in a 3-week parallel, single-blind, randomized, controlled clinical trial. The test group used a tongue cleaner, a tooth/tongue gel and mouthwash containing amine fluoride/stannous fluoride and zinc lactate as oral malodour counteractive. Read More

    Self-repaired Process of a Traumatized Maxillary Central Incisor with Pulp Infarct after Horizontal Root Fracture Monitored by Laser Doppler Flowmetry Combined with Tissue Oxygen Monitor.
    J Endod 2017 Jul 17;43(7):1218-1222. Epub 2017 May 17.
    State Key Laboratory of Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
    Achieving a precise diagnosis of the pulp status of traumatized teeth is difficult. The time to interfere through endodontic treatment for these teeth is greatly dependent on the doctor's experience. A 24-year-old male patient suffered a traumatic injury to tooth #9 that resulted in an apical root horizontal fracture 3 days before he came to the hospital. Read More

    An Evidence-based Review of the Efficacy of Treatment Approaches for Immature Permanent Teeth with Pulp Necrosis.
    J Endod 2017 Jul 13;43(7):1052-1057. Epub 2017 May 13.
    Department of Endodontics, New York University College of Dentistry, New York, New York.
    Introduction: Two fundamental assumptions for teeth treated with regenerative endodontic procedures (REPs) are (1) that the clinical outcome is comparable with the traditional techniques of calcium hydroxide apexification and mineral trioxide aggregate apical barrier techniques and (2) that REPs will result in further root maturation.

    Methods: A systematic review of the electronic databases (Scopus, PubMed, and Web of Science) involved a search for studies that used quantitative assessments of root maturation. The search terms were "dental pulp," "regenerative endodontic therapy," "revascularization," and "revitalization. Read More

    Bovine Tooth Discoloration Induced by Endodontic Filling Materials for Primary Teeth.
    Int J Dent 2017 5;2017:7401962. Epub 2017 Apr 5.
    Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil.
    This study evaluated the discoloration potential of endodontic materials used in primary teeth.Dentine-enamel blocks were prepared from 75 bovine teeth, assorted in five experimental groups (= 15). The tested materials included an MTA-based material; zinc oxide and eugenol cement (ZOE); Vitapex; and calcium hydroxide thickened with zinc oxide (Calen + ZO). Read More

    Functional and esthetic rehabilitation of a child with amelogenesis imperfecta: a case report.
    Gen Dent 2017 May-Jun;65(3):e18-e20
    Amelogenesis imperfecta (AI) is a tooth disorder characterized by the abnormal development of the enamel in response to mutations in the genes involved in amelogenesis. The objective of this article is to present the clinical case of a child with AI in the primary dentition phase. A 4-year-old boy was presented to a clinic by his mother, who complained that her son's smile esthetics were compromised by "weak and yellow teeth. Read More

    Rare sequelae in the permanent successor due to trauma in the primary incisor: a case report.
    Gen Dent 2017 May-Jun;65(3):62-64
    Severe dental trauma-such as intrusion or avulsion-to the primary dentition in infants and toddlers may cause developmental disturbances in the permanent successor. In this case, a 9-year-old boy was referred for treatment due to the absence of his permanent maxillary right central incisor. The mother reported avulsion of the corresponding primary tooth when the patient was 2 years old. Read More

    [Comparison of clinical effects of Co-Cr alloy cast post-core and everStick fiber post in restoration of labially or lingually inclined maxillary central incisor].
    Shanghai Kou Qiang Yi Xue 2017 Feb;26(1):89-93
    Department of Prosthodontics, Shanghai Stomatological Disease Center, Shanghai Stomatological Hospital. Shanghai 200031, China.
    Purpose: To compare the clinical effect of Co-Cr alloy cast post-core and everStick fiber post in restoration of maxillary central incisor with labial or lingual inclination, and provide theoretical basis for clinical application.

    Methods: Ninety-seven labially or lingually inclined maxillary central incisors were treated in our hospital from March 2012 to March 2014. The patients were randomly divided into group A (n=49) and group B (n=48), and received post -core and crown restoration. Read More

    Analyses ofMissense Mutations in Two Families with Hypomaturation Amelogenesis Imperfecta.
    Front Physiol 2017 20;8:229. Epub 2017 Apr 20.
    Department of Molecular Genetics and Dental Research Institute, School of Dentistry, Seoul National UniversitySeoul, Korea.
    Amelogenesis imperfecta is a group of rare inherited disorders that affect tooth enamel formation, quantitatively and/or qualitatively. The aim of this study was to identify the genetic etiologies of two families presenting with hypomaturation amelogenesis imperfecta. DNA was isolated from peripheral blood samples obtained from participating family members. Read More

    Effects of clarithromycin treatment in scrub typhus in children: comparison with chloramphenicol and azithromycin.
    Korean J Pediatr 2017 Apr 25;60(4):124-127. Epub 2017 Apr 25.
    Department of Pediatrics, Chonbuk National University Children's Hospital, Jeonju, Korea.
    Purpose: Chloramphenicol and tetracycline are not recommended for treating scrub typhus in pediatric patients because of potential side effects, such as aplastic anemia or tooth discoloration. While clarithromycin has recently been used in adults, few reports have been published on its effects in pediatric patients. We report the clinical profiles of pediatric scrub typhus and the effects of clarithromycin on scrub typhus in children. Read More

    Correction of a Single Discolored Anterior Tooth Due to Internal Resorption: A Clinical Report.
    Compend Contin Educ Dent 2017 May;38(5):e13-e16
    Assistant Professor, Oral Rehabilitation Department, Dental College of Georgia at Augusta University, Augusta, Georgia.
    For patients with a single discolored tooth who desire to have it lightened, a thorough examination and radiographic analysis need to be performed prior to initiating any bleaching treatment so that the cause of the discoloration can be determined. Underlying pathology, such as internal resorption, is often asymptomatic and difficult to diagnose and if left untreated could result in tooth loss. This article describes a case of a patient with a discolored maxillary central incisor resulting from internal resorption and the subsequent endodontic and bleaching therapy performed to resolve the pathology and achieve an acceptable esthetic result. Read More

    Provider Perceptions of Treatment Options for Immature Permanent Teeth.
    J Endod 2017 Jun 27;43(6):910-915. Epub 2017 Apr 27.
    Department of Endodontics, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina. Electronic address:
    Introduction: Current treatment options for immature permanent teeth with pulpal necrosis include both apexification and regenerative endodontics. The purpose of this study was to survey endodontists on the use of these 2 treatment options.

    Methods: Surveys were created by using Qualtrics and Teleform software and distributed by using the Salant and Dillman method. Read More

    Spectrophotometric analysis of fluorescent zirconia abutments compared to "conventional" zirconia abutments: A within subject controlled clinical trial.
    Clin Implant Dent Relat Res 2017 Aug 24;19(4):760-766. Epub 2017 Apr 24.
    Division of Fixed Prosthodontics and Biomaterials, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.
    Background: Zirconia abutments are frequently used for implant-supported single crowns. Even though demonstrating esthetic benefits compared to metal abutments, zirconia abutments lead to an increased brightness of the peri-implant mucosa compared to natural teeth and are not ideal from an esthetic point of view.

    Purpose: To test whether or not a fluorescent hybrid zirconia abutment offers superior esthetics compared to a non-fluorescent one-piece zirconia abutment based on spectrophotometric analysis. Read More

    Minocycline-Induced Hyperpigmentation in a Patient Treated with Erlotinib for Non-Small Cell Lung Adenocarcinoma.
    Case Rep Oncol 2017 Jan-Apr;10(1):156-160. Epub 2017 Feb 15.
    Walter Reed National Military Medical Center, Bethesda, MD, USA.
    Introduction: While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxycycline.

    Case: We present a case of an 87-year-old man who developed a severe papulopustular skin eruption secondary to erlotinib therapy for NSCLC. Control of the eruption with 100 mg of minocycline twice daily for 8 months eventually led to blue-gray skin hyperpigmentation. Read More

    The end of a dogma: the safety of doxycycline use in young children for malaria treatment.
    Malar J 2017 Apr 13;16(1):148. Epub 2017 Apr 13.
    Unité de Parasitologie et d'Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, HIA Laveran, Boulevard Laveran, 13013, Marseille, France.
    Anti-malarial drug resistance to chloroquine and sulfadoxine-pyrimethamine has spread from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to artemisinin-based combination therapy (ACT) in Southeast Asia highlights the need to identify new anti-malarial drugs. Doxycycline is recommended for malaria chemoprophylaxis for travel in endemic areas, or in combination with the use of quinine for malaria treatment when ACT is unavailable or when the treatment of severe malaria with artesunate fails. Read More

    Crown discoloration promoted by materials used in regenerative endodontic procedures and effect of dental bleaching: spectrophotometric analysis.
    J Appl Oral Sci 2017 Mar-Apr;25(2):234-242
    Universidade Federal de Santa Catarina, Departamento de Odontologia, Florianópolis, Santa Catarina, Brasil.
    Objectives: To assess tooth crown's color after intracanal treatment with triple antibiotic paste (TAP) or calcium hydroxide (CH); cervical sealing with glass ionomer cement (GIC) or mineral trioxide aggregate (MTA); and bleaching with carbamide peroxide.

    Material And Methods: After pulp removal and color spectrophotometer measurement, 50 bovine incisors were divided into 4 experimental groups and one control (untreated). Experiments were performed in phases (Ph). Read More

    Color stability of ceramic laminate veneers cemented with light-polymerizing and dual-polymerizing luting agent: A split-mouth randomized clinical trial.
    J Prosthet Dent 2017 Nov 3;118(5):604-610. Epub 2017 Apr 3.
    Adjunct Professor, Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Santa Maria, Rio Grande do Sul, Brazil.
    Statement Of Problem: The color stability of luting agents influences the esthetics of ceramic laminate veneers. Clinical studies that have evaluated the color changes of veneers cemented to enamel with light- and dual-polymerizing resin cement are lacking.

    Purpose: The purpose of this split-mouth randomized clinical trial was to evaluate the color change and marginal discoloration of dual- and light-polymerizing cement used for cementation of ceramic laminate veneers. Read More

    Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.
    Cochrane Database Syst Rev 2017 03 31;3:CD008676. Epub 2017 Mar 31.
    Cochrane Oral Health, Division of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, JR Moore Building, Oxford Road, Manchester, UK, M13 9PL.
    Background: Dental plaque associated gingivitis is a reversible inflammatory condition caused by accumulation and persistence of microbial biofilms (dental plaque) on the teeth. It is characterised by redness and swelling of the gingivae (gums) and a tendency for the gingivae to bleed easily. In susceptible individuals, gingivitis may lead to periodontitis and loss of the soft tissue and bony support for the tooth. Read More

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