Search Our Scientific Publications & Authors

Scand J Urol 2020 Jun 5:1-7. Epub 2020 Jun 5.

Department of Urology, University Hospital of Würzburg, Eberhard-Karls University, Tuebingen, Germany.

To examine whether previous tonsillectomy (TE) impacts on survival after radical cystectomy (RC) for bladder cancer (BC). A total of 320 patients were staged cM0 and underwent RC for BC between 2002 and 2013. We retrospectively investigated whether patients had undergone TE prior to RC. Read More

Cureus 2020 May 3;12(5):e7945. Epub 2020 May 3.

Otolaryngology, King Abdulaziz University Hospital, Jeddah, SAU.

Background Adenoidectomy is the most commonly performed pediatric operation worldwide and one of the most frequent otorhinolaryngological procedures. It is a safe procedure with a low risk of complications. However, after a successful adenoidectomy, few patients experience symptoms of nasal obstruction, suggestive of adenoid regrowth. Read More

Transpl Infect Dis 2020 Jun 4:e13347. Epub 2020 Jun 4.

Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA, USA.

Kaposi sarcoma (KS) is a vascular neoplasm caused by human herpesvirus-8 (HHV-8) infection. KS is most often seen in individuals with acquired immunodeficiency syndrome but can occur in patients who are on immunosuppressive therapy. While the skin and oral mucosa are the typical site for KS, lesions of the tonsil are quite rare with only a few reported cases. Read More

Cureus 2020 Apr 26;12(4):e7842. Epub 2020 Apr 26.

Anesthesiology, Shiraz Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, IRN.

Introduction Coughing is commonly observed during emergence from general anesthesia. In children, smooth emergence from anesthesia, especially after tonsillectomy, is crucial. In this study, we compared the effect of low-dose ketamine or propofol on emergence coughing in children undergoing tonsillectomy. Read More

Vestn Otorinolaringol 2020 ;85(2):26-30

Saint Petersburg Research Institute of Ear, Throat, Nose and Speech of the Ministry of Health of Russia, Saint Petersburg, Russia.

The Objective: Of the work was to describe the basics of a meta-analysis with features for evaluating models with fixed and random effects, to present principles for interpreting the graphical results of a meta-analysis (forest plot or blobogram) of comparative reviews of randomized clinical trials (RCTs).

Material And Methods: To illustrate the possibility of efficient use of the R software environment for meta-analysis, we used the results of RCTs of various tonsillectomy methods already published in the Cochrane Database review.

Results: The article provides explanations for the calculation of effect size, heterogeneity statistic, and other meta-analysis statistics and their interpretation for evaluating RCTs and recommendations for choosing a model depending on the on the general research concept. Read More

Am J Otolaryngol 2020 May 16;41(4):102546. Epub 2020 May 16.

The Center for Pediatric ENT - Head & Neck Surgery, 10150 Hagen Ranch Rd, Suite B-900, Boynton Beach, FL 33437, United States; Florida Atlantic University Charles E. Schmidt College of Medicine, 777 Glades Road, BC-71, Boca Raton, FL 33431, United States. Electronic address:

Purpose: The primary purpose of this study was to assess the overall rate of postoperative complications after adenotonsillectomy in children under 24 months old relative to children 24-36 months old. Our secondary goal focused on quantifying specific preoperative risk factors that predispose children to postoperative complications.

Methods: We retrospectively reviewed 248 patients who underwent adenotonsillectomy at our ENT office from 2006 to 2011. Read More

J Ayub Med Coll Abbottabad 2020 Jan- Mar;32(1):94-98

Army Burn Hall College (For Girls), Abbottabad, Pakistan.

Background: This study aims toward establishing the impact of prophylactic pre-operative antimicrobial therapy on tonsillectomy related haemorrhage.

Methods: In this randomized controlled trial conducted at Combined Military Hospital, Abbottabad from January 2017 till August 2019, 121 children and adult patients who had consented and had undergone tonsillectomy were evaluated for procedure related haemorrhage.

Results: Incidence rate of secondary posttonsillectomy haemorrhage and need for re-hospitalization was significantly less in patients who had completed pre-operative prophylactic antibiotics. Read More

J Pediatr Pharmacol Ther 2020 ;25(4):303-308

Objective: Postoperative nausea and vomiting (PONV) is an extremely common side effect of general anesthesia that is difficult to manage. We tested a hypothesis that an aggressive prophylactic intervention with additional antiemetic drugs will reduce the incidence of PONV in a high-risk pediatric population undergoing adenotonsillectomy.

Methods: In this retrospective study, pediatric patients undergoing adenotonsillectomy were screened for their risk factors for PONV. Read More

Eur Arch Otorhinolaryngol 2020 May 25. Epub 2020 May 25.

Department of Otorhinolaryngology, Plastic Head and Neck Surgery, Kliniken Maria Hilf, Viersener Str. 450, 41063, Mönchengladbach, Germany.

Purpose: To evaluate, whether the regional variability of tonsil surgery in terms of the 16 Federal States of Germany was mirrored by a comparable variability of bleeding complications in male and female patients.

Methods: A longitudinal population-based inpatient cohort study was performed including all patients who had undergone tonsil surgery between 2005 and 2018. The database was provided by the Federal Statistical Office of Germany and included all inpatient cases after tonsillectomy (with or without adenoidectomy), tonsillotomy, abscess-tonsillectomy and secondary tonsillectomy. Read More

Eur Arch Otorhinolaryngol 2020 May 25. Epub 2020 May 25.

Otolaryngology Department, Pedro Hispano Hospital, Matosinhos, Oporto, Portugal.

Purpose: Tonsillectomy is one of the most common surgical procedures in otorhinolaryngology. Hemorrhage in the postoperative period has an incidence of up to 20% and is a potentially fatal complication. We aim to assess the incidence of hemorrhage after tonsillectomy in our institution, and to evaluate and identify the possible associated risk factors. Read More

Otolaryngol Head Neck Surg 2020 May 26:194599820917394. Epub 2020 May 26.

Department of Otolaryngology Head and Neck Surgery, University of West Virginia, Morgantown, West Virginia, USA.

Objectives: To assess the exposure of surgical personnel to known carcinogens during pediatric tonsillectomy and adenoidectomy (T&A) and compare the efficacy of surgical smoke evacuation systems during T&A.

Study Design: Prospective, case series.

Setting: Tertiary children's hospital. Read More

Otolaryngol Head Neck Surg 2020 May 26:194599820922155. Epub 2020 May 26.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Objective: Clinical practice guidelines synthesize and disseminate the best available evidence to guide clinical decisions and increase high-quality care. Since 2004, the American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) has published 16 guidelines. The objective of this review was to evaluate clinicians' adherence to these guidelines' recommendations as measured in the literature. Read More

J Clin Sleep Med 2020 May 22. Epub 2020 May 22.

Department of Otolaryngology-Head and Neck Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Study Objectives: To investigate the fiber type distribution in palatopharyngeal muscle via adenosine triphosphatase (ATPase) and Quantitative Real-time Polymerase Chain Reaction (qRT-PCR) in children with severe obstructive sleep apnea (OSA).

Methods: There were 12 severe childhood OSA undergoing tonsillectomy, while 15 simple snoring as control group. Both groups were diagnosed by polysomnography (PSG). Read More

Pain Rep 2020 Mar-Apr;5(2):e819. Epub 2020 Mar 6.

Department of Pain Medicine, Palliative Care and Integrative Medicine, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN, USA.

Pediatric tonsillectomy involves an often painful and lengthy recovery period, yet the extended recovery process is largely unknown. This article describes postoperative recovery outcomes for 121 children aged 4 to 15 (mean 6.6 years, SD = 2. Read More

Acta Otolaryngol 2020 May 21:1-8. Epub 2020 May 21.

Department of Otorhinolaryngology, Region Jönköping County, Jönköping, Sweden.

To assure a high quality in tonsil surgery, it is necessary to monitor trends in clinical practice, complications and outcome. To describe rates and trends regarding indications, methods, techniques, complications, and outcome of tonsil surgery. 98 979 surgeries from the National Tonsil Surgery Register 2009-2018. Read More

BMC Infect Dis 2020 May 20;20(1):358. Epub 2020 May 20.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Globally, in 2012, about 1.2 million estimated cases were reported with ~ 135,000 deaths annually. In Ethiopia, specifically in our study area, limited information is found on the oropharyngeal carriage, antimicrobial resistance pattern, and associated risk factors for N. Read More

Eur Arch Otorhinolaryngol 2020 May 19. Epub 2020 May 19.

Department of Corporate Education in Nursing of Hospital da Criança Santo Antônio/Postgraduate Program in Pediatrics, Irmandade da Santa Casa de Misericórdia de Porto Alegre/Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.

Purpose: Nausea and vomiting occur in up to 70% of children after adenotonsillectomy, ingested blood during procedure being one of the reasons for emesis. Hypopharyngeal packing (HP) is a common practice among otolaryngologists to prevent blood from being swallowed, but studies in nasal surgeries in adults failed to show efficacy of this technique in reducing postoperative nausea and vomiting (PONV). There are no studies evaluating the effect of HP in adenotonsillectomy in children. Read More

Otolaryngol Head Neck Surg 2020 May 19:194599820926456. Epub 2020 May 19.

Department of Otolaryngology/Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon, USA.

Objective: To assess the impact of the 2011 American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guideline on practice patterns in obtaining preadenotonsillectomy (AT) polysomnography (PSG) for pediatric sleep-disordered breathing (SDB).

Study Design: Retrospective cohort study.

Setting: Tertiary children's hospital. Read More

Otolaryngol Head Neck Surg 2020 May 19:194599820923625. Epub 2020 May 19.

Department of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Objective: To evaluate whether plasma ablation tonsillectomy is superior to other hot techniques in reducing postoperative morbidity.

Data Sources: The databases of PubMed, EMBASE, and Web of Science were used to search the literature, from inception to January 2, 2020. Randomized controlled trials (RCTs) that compared plasma ablation tonsillectomy with any other hot techniques were eligible. Read More

Int J Pediatr Otorhinolaryngol 2020 May 11;135:110106. Epub 2020 May 11.

UCI Center on Stress & Health, School of Medicine, University of California-Irvine, Irvine, CA, 505 S Main Street, Suite 940, Orange, CA, 92868, USA; Department of Anesthesiology and Perioperative Care, University of California-Irvine, 333 City Blvd West, Orange, CA, 92868, USA; Sue & Bill Gross School of Nursing, University of California-Irvine, 802 W Peltason Drive, Irvine, CA, 92697, USA; Department of Pediatric Psychology, CHOC Children's, Orange, CA, 1201 West La Veta Ave, Orange, CA, 92868, USA. Electronic address:

Objectives: Using multiple well-validated measures and a large sample size, the goal of this paper was to describe the immediate clinical and behavioral recovery of children following tonsillectomy with or without an adenoidectomy (T&A) during the first two weeks following surgery.

Study Design: Observational, longitudinal study.

Setting: Four major pediatric hospitals in the U. Read More

Adv Health Sci Educ Theory Pract 2020 May 16. Epub 2020 May 16.

Centre for Education Research and Innovation, Schulich School of Medicine and Dentistry, Western University, London, Canada.

Surgeons practice their own variations on a procedure. Residents experience shifting thresholds between variations that one surgeon holds firmly as principle and another takes more lightly as preference. Such variability has implications for surgical education, but the impact is not well understood. Read More

Eur Arch Otorhinolaryngol 2020 May 16. Epub 2020 May 16.

Department of Clinical Science, Intervention and Technology, CLINTEC, Karolinska Institutet, Stockholm, Sweden.

Purpose: In our previous randomized controlled trial (RCT), comparing adenotonsillectomy (ATE) with adenopharyngoplasty (APP) in children with severe obstructive sleep apnea (OSA), there were no differences in respiratory sleep parameters or quality of life. The purpose of the present report was to evaluate postoperative morbidity from this RCT.

Methods: The study was a blinded RCT in 83 children (ATE = 47; APP = 36), 2-4 years of age, with an obstructive apnea-hypopnea index of ≥ 10. Read More

Mult Scler Relat Disord 2020 Apr 28;42:102131. Epub 2020 Apr 28.

Jacobs MS Center for Treatment and Research, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA. Electronic address:

Background: Previous studies have shown an effect of tonsillectomy and greater risk for future autoimmune diseases. Currently there are only few outdated analyses of tonsillectomy and multiple sclerosis (MS) risk.

Objective: To investigate the prevalence of tonsillectomy in MS patients and healthy controls (HCs). Read More

Int J Pediatr Otorhinolaryngol 2020 Apr 30;134:110077. Epub 2020 Apr 30.

Department of Otorhinolaryngology/Head and Neck Surgery, Oslo University Hospital, Oslo, Norway; University of Oslo, Institute of Clinical Medicine, Oslo, Norway.

Objectives: Obstructive sleep apnea (OSA) can have a negative impact on quality of life in children. The OSA-18 is a disease-specific quality of life questionnaire for children. The questionnaire has been found to be a poor predictor of OSA diagnosed with polysomnography (PSG), yet OSA-18 scores do markedly improve after adenotonsillectomy. Read More

Sleep Breath 2020 May 12. Epub 2020 May 12.

Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Purpose: Left untreated, obstructive sleep-disordered breathing (OSDB) are associated with adverse effects on growth and development. History and physical examination alone are used for diagnosing children with OSDB, as polysomnography is not always feasible. Our objective was to develop and validate a Hebrew version of the Pediatric Sleep Questionnaire (PSQ) to help to diagnose and follow-up children before and after adenotonsillectomy surgery for OSDB. Read More

Eur Arch Otorhinolaryngol 2020 May 9. Epub 2020 May 9.

Department of ENT, Kayseri City Training and Research Hospital, Şeker Mah. Muhsinyazıcıoğlu Bulvarı No:77 Kocasinan, 38080, Kayseri, Turkey.

Purpose: To assess the validity of simplified pain scales, including the Simplified Faces Pain Scale (S-FPS) and Simplified Concrete Ordinal Scale (S-COS) in preschool-age children who underwent adenotonsillectomy (T&A) by comparing the values of simplified pain scales with the Faces Pain Scale-Revised (FPS-R) and the Faces, Legs, Activity, Cry, Consolability (FLACC) observational pain scale.

Methods: The present study consisted of 100 pediatric patients between the ages of 3 and 6 years old who had T&A. A two-step pain assessment approach with S-FPS and S-COS and FPS-R and FLACC pain scales was performed with children with the help of their parents or caregivers at the 1st, 6th and 12th hours, and over the 7 days after surgery. Read More

Int J Pediatr Otorhinolaryngol 2020 Apr 27;134:110072. Epub 2020 Apr 27.

Department of Otolaryngology Clinic, Mardin Public Hospital, Mardin, Turkey.

Introduction: Adenoidectomy and adenotonsillectomy are very common operations in childhood. It is important to clarify their effects on this age group; in this study, we aimed to investigate the effects of the causative agent on children's mental health by using scales that help to screen for indications of mental disorders in children, who have had adenoidectomy or adenotonsillectomy, both before and after surgery. In this way, we aimed to investigate the effects of this factor on children's mental health. Read More

Clin Otolaryngol 2020 May 9. Epub 2020 May 9.

University of Kansas-School of Medicine, Kansas City, Kansas, USA.

Objectives: To determine the standardised body mass index (BMIz) trajectory before and after adenotonsillectomy/tonsillectomy between children in different weight classifications in a larger sample than has been studied previously, and to identify which patient factors would explain the difference in these outcomes.

Design: We used a retrospective chart review and leveraged data of weight status pre- and post-adenotonsillectomy/tonsillectomy from a cohort of paediatric patients seen between May 2004 and April 2017.

Setting: Data were collected from an electronic medical record at a single Midwest paediatric health system. Read More

Pediatr Res 2020 May 9. Epub 2020 May 9.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.

Background: Approximately 500,000 children undergo tonsillectomy and adenoidectomy (T&A) annually for treatment of obstructive sleep disordered breathing (oSDB). Although polysomnography is beneficial for preoperative risk stratification in these children, its expanded use is limited by the associated costs and resources needed. Therefore, we used machine learning and data from potentially wearable sensors to identify children needing postoperative overnight monitoring based on the polysomnographic severity of oSDB. Read More

Anaesthesist 2020 May 6. Epub 2020 May 6.

Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.

Crouzon syndrome (CS) is a rare autosomal dominant inherited disorder caused by mutations in the fibroblast growth factor receptor 2 (FGFR2) gene. The disease is characterized by premature fusion of the coronal and sagittal sutures of the skull, resulting in clinical manifestations of midfacial hypoplasia, shallow orbit, maxillary dysplasia, and occasional upper respiratory obstruction. This article presents the case of a child aged 2 years and 7 months with CS scheduled for bilateral tonsillectomy and adenoidectomy. Read More

Acta Chir Belg 2020 May 19:1-3. Epub 2020 May 19.

Department of Radiology, University Hospitals Leuven, Leuven, Belgium.

Postoperative lingual artery pseudoaneurysm associated with hemorrhage is a rare entity mainly found after tonsillectomy or laryngectomy. In this report, a symptomatic, lingual artery pseudoaneurysm after repeated base of tongue surgery was identified on computed tomography and successfully managed with catheter-directed glue-embolization. Read More

ORL J Otorhinolaryngol Relat Spec 2020 May 6:1-8. Epub 2020 May 6.

Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Azienda USL della Romagna, Forlì, Italy.

Background: A new transoral tongue base surgical procedure for the treatment of snoring and obstructive sleep apnea (OSA) is described. It is named "Robo-Cob" technique because it is similar to transoral robotic surgery (TORS) but it is performed by means of coblation technology in order to resect the tongue base in countries where TORS is not an available option for such benign conditions.

Methods: In this prospective, randomized, controlled trial, the new Robo-Cob technique was carried out in 25 adult OSA patients with confirmed tongue base hypertrophy at preoperative drug-induced sedation endoscopy. Read More

J Craniofac Surg 2020 May 4. Epub 2020 May 4.

Ear, Nose, and Throat Department, Başkent University, Ankara Hospital, Ankara, Turkey.

Elongation of the stylohyoid process or calcification of the stylohyoid ligament is known as the Eagle syndrome. Mostly, it is seen incidentally on imaging or with extreme suspicion and usually patients are asymptomatic.Surgery is the preferred method in symptomatic patients. Read More

Int J Pediatr Otorhinolaryngol 2020 Apr 27;134:110073. Epub 2020 Apr 27.

Boston University School of Medicine, 72 E Concord St, Boston, MA, 02118, USA; Boston University Medical Center, Department of Otolaryngology, 800 Harrison Ave, BCD Building, 5th Floor, Boston, MA, 02118, USA. Electronic address:

Objective: Assessment of adenoid hypertrophy can be completed through various methods including flexible endoscopy and intraoperative mirror exam. The objective of this study was to compare the effect of adenoid size on the accuracy of these techniques.

Methods: Patients younger than 18 years old who underwent adenoidectomy at Boston Medical Center from October 2012 to December 2018 and had documented preoperative and intraoperative adenoid sizes were included. Read More

Clin Otolaryngol 2020 May 5. Epub 2020 May 5.

IWK Health Centre, Halifax, NS, Canada.

Objectives: Physician and patient/parent communication is of utmost importance in consultations to improve the shared decision-making (SDM) processes. This study investigated SDM-related outcomes through turn analysis and an assessment of patient-centred dialogue.

Design: Multi-centre prospective cohort study analysing audio- and video-recorded patient/parent-physician interactions. Read More

Otolaryngol Head Neck Surg 2020 May 5:194599820921392. Epub 2020 May 5.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Objective: To better characterize associations between and tonsillolith versus nontonsillolith tonsillectomy specimens.

Study Design: Bi-institutional retrospective case-case study.

Setting: University and county hospital. Read More

Int J Pediatr Otorhinolaryngol 2020 Apr 24;134:110066. Epub 2020 Apr 24.

Department Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO, USA. Electronic address:

Tonsillectomy is a common procedure in the pediatric population, with subsequent microscopic examination of the specimen for cancer and other rare diagnoses occurring routinely. A 17 year-old female with a history of autoimmune vasculitis underwent adenotonsillectomy for severe obstructive sleep apnea. Pathology demonstrated small, medium and large lymphocytes and plasma cells obscuring the lymphoid follicles and germinal centers, with few Epstein-Barr virus positive lymphocytes. Read More

Medicine (Baltimore) 2020 May;99(18):e19793

Department of Otorhinolaryngology - Head and Neck Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, South Korea.

Rationale: Many previous studies have investigated the necessity of routine histopathological analysis of tonsillectomy specimen, and most recent studies have suggested that such an analysis is not justified in asymptomatic patients or those with no risk factors for malignancy.

Patient Concerns: A 59-year-old man diagnosed with obstructive sleep apnea underwent surgery, including tonsillectomy; a tonsil specimen was sent to the department of pathology.

Diagnosis: Although the patient did not exhibit any tonsil-related signs or symptoms, nor did the appearance of the tonsil appear to be pathological, the right tonsil specimen was diagnosed with squamous cell carcinoma, with detection of human papilloma virus 16. Read More

Cochrane Database Syst Rev 2020 05 1;5:CD008268. Epub 2020 May 1.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: Sore throat is a common condition associated with a high rate of antibiotic prescriptions, despite limited evidence for the effectiveness of antibiotics. Corticosteroids may improve symptoms of sore throat by reducing inflammation of the upper respiratory tract. This review is an update to our review published in 2012. Read More

Am Fam Physician 2020 May;101(9):521

J Pediatr Intensive Care 2020 Jun 14;9(2):149-150. Epub 2020 Jan 14.

Department of Anaesthesiology, MITERA Infirmary, Athens, Greece.

Case Rep Hematol 2020 14;2020:2765012. Epub 2020 Apr 14.

Department of Haematology, Oslo University Hospital, Oslo, Norway.

Patients with sickle cell disease (SCD) suffer from anemia and painful vaso-occlusive crisis (VOC) and sometimes need blood transfusions. Delayed hemolytic transfusion reaction (DHTR) is a rare life-threatening complication observed in SCD and mimics VOC. We describe a female SCD patient undergoing three surgical procedures during which DHTR developed following the first two. Read More

Cochrane Database Syst Rev 2020 04 29;4:CD011365. Epub 2020 Apr 29.

evidENT, Ear Institute, University College London, London, UK.

Background: Obstructive sleep-disordered breathing (oSDB) is a condition encompassing breathing problems when asleep due to upper airway obstruction. In children, hypertrophy of the tonsils and/or adenoids is thought to be the commonest cause. As such, (adeno)tonsillectomy has long been the treatment of choice. Read More

Ann R Coll Surg Engl 2020 Apr 29:1-9. Epub 2020 Apr 29.

St George's University Hospitals NHS Foundation Trust, Tooting, London, UK.

Introduction: Head and neck carcinoma of unknown primary represents 1-5% of all head and neck cancers and presents a diagnostic and therapeutic dilemma. In approximately 40% of cases, a primary tumour location remains unknown despite investigation. With advancements in our understanding of the role of high-risk human papilloma virus in head and neck cancer, transoral robotic surgery presents an option for diagnosis and therapy. Read More

Paediatr Drugs 2020 Jun;22(3):243-250

Unité Romande d'immuno-rhumatologie Pédiatrique, CHUV, University of Lausanne, Lausanne, and HUG, Geneva, Switzerland.

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is characterized by recurrent fever flares accompanied by symptoms and signs forming the disease acronym and alternating with asymptomatic periods. Despite the disease having a generally favorable outcome, with spontaneous remission after a few years, it does have a major impact on the quality of life of the child and his or her relatives. Beside symptomatic medications during fever flares, the most used treatment consists of a single dose of corticosteroids at flare onset to interrupt the attack; fever resolves usually within a few hours, but often with a shorter interval between the attacks. Read More

Laryngoscope Investig Otolaryngol 2020 Apr 11;5(2):210-216. Epub 2020 Feb 11.

Department of Radiation Oncology Washington University School of Medicine in St. Louis St. Louis Missouri.

Objectives: We investigated how tonsillectomy during childhood may influence the distribution of human papillomavirus (HPV) positive cancer of the tonsils in adult life using p16 as a surrogate marker for HPV infection.

Study Design: Retrospective observational study.

Methods: A total of 280 patients diagnosed with oropharyngeal squamous cell carcinoma (OPSCC) and known p16 status were eligible for this study. Read More

J Otolaryngol Head Neck Surg 2020 Apr 23;49(1):21. Epub 2020 Apr 23.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of British Columbia, 2775 Laurel Street, 4th floor, Vancouver, BC, V5Z 1M9, Canada.

Background: Obstructive sleep apnea is an expected competency for Otolaryngology - Head and Neck surgery residents and tested on the Royal College of Physicians and Surgeons examination. Our objective was to evaluate the knowledge, attitudes and confidence of Canadian Otolaryngology - Head and Neck surgery residents in managing Obstructive Sleep Apnea (OSA) patients.

Methods: An anonymous, online, cross-sectional survey was distributed to all current Canadian Otolaryngology-Head and Neck surgery residents according to the Dillman Tailored Design Method in English and French. Read More

Pediatr Int 2020 Apr 21. Epub 2020 Apr 21.

Department of Pediatrics, Kindai University, Faculty of Medicine, Osaka-Sayama, Japan.

Background: Early multiple-drug therapy for severe childhood IgA nephropathy prevents the progression of nephritis and improves long-term prognosis. Recent studies have focused on the relationship between the pathophysiology of IgA nephropathy and tonsillar focal infection, and the efficacy of tonsillectomy with methylprednisolone pulse therapy in children has been demonstrated. However, no study has reported on the relationship between the period from diagnosis to tonsillectomy and the long-term prognosis of IgA nephropathy. Read More

Turk Arch Otorhinolaryngol 2020 Mar 5;58(1):30-34. Epub 2019 Oct 5.

Department of Otorhinolaryngology, Van Yüzüncü Yıl University School of Medicine, Van, Turkey.

Objective: This study was conducted to compare two different surgical methods; partial tonsil resection using the bipolar technique, tonsillotomy (TT), and total tonsillectomy (TE) (blunt dissection) for recurrent tonsillitis in children. The frequency of recurrent throat infections was determined during postoperative follow-up.

Methods: A total of 393 patients were included in this study. Read More

J Laryngol Otol 2020 Apr 20:1-5. Epub 2020 Apr 20.

Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Objective: Post-surgical bleeding after tonsillectomy occurs in 2-7 per cent of cases. This study examined whether heart rate and haematocrit changes are associated with the amount of bleeding.

Method: In this retrospective analytical study, data were collected from the medical charts of patients admitted with post-surgical bleeding. Read More