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Oral Oncol 2022 Jun 22;132:105981. Epub 2022 Jun 22.

Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 Lingyuanxi Road, Guangzhou 510055, Guangdong, China; Guangdong Provincial Key Laboratory of Stomatology, No. 74, 2nd Zhongshan Road, Guangzhou 510080, Guangdong, China. Electronic address:

Objectives: To investigate the recovery process of swallowing function and ascertain swallowing pattern in patients undergoing total glossectomy (TG).

Materials And Methods: A cohort study was conducted in consecutive patients with tongue squamous cell carcinoma who received TG/hemiglossectomy (HG) from May 2017 to December 2019. Exposure factors included tongue resection range (HG and TG) and postoperative radiotherapy (PRT and non-PRT). Read More

Food Chem 2022 Jun 16;394:133504. Epub 2022 Jun 16.

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315211, Zhejiang, China. Electronic address:

The existing technology used for screening umami peptides is time-consuming and labor-intensive, making it difficult to meet the requirements of rapid screening of peptides. In this study, a high-throughput screening method for umami peptides was established based on peptidomics and virtual screening including the mass spectrometry, iUmami-SCM, PeptideRanker, and T1R1/T1R3 receptor. Subsequently, they were characterized and validated using sensory evaluation and electronic tongue. Read More

Clin Exp Dent Res 2022 Jun 24. Epub 2022 Jun 24.

Division of General Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

Background: Sarcopenia is prevalent in patients with chronic kidney disease (CKD), which is defined as a low estimated glomerular filtration rate (eGFR). It has been reported that oral hypofunction characterized by decreased tongue pressure is related to sarcopenia. Although there are several previous reports regarding the association of renal dysfunction with oral hypofunction characterized by low tongue pressure, the association between tongue pressure and renal function is not fully understood. Read More

Elife 2022 Jun 24;11. Epub 2022 Jun 24.

Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany.

The tongue is a unique muscular organ situated in the oral cavity where it is involved in taste sensation, mastication, and articulation. As a barrier organ, which is constantly exposed to environmental pathogens, the tongue is expected to host an immune cell network ensuring local immune defence. However, the composition and the transcriptional landscape of the tongue immune system are currently not completely defined. Read More

Rocz Panstw Zakl Hig 2022 ;73(2):231-237

Department of Oral Medicine and Radiology, Sharavathi Dental College and Hospital, Shivamogga, Karnataka, India.

Background: Just mere brushing of teeth is not enough for maintaining good oral health. Regular cleaning of tongue is equally important for maintaining good oral hygiene and to escape social embarrassment and personal discomfort, which could arise as a result of halitosis.

Objective: To test the variables of Theory of Reasoned Action to explain the behavior of tongue cleaning among college going students of Udaipur city, Rajasthan, India. Read More

Physiol Rep 2022 Jun;10(12):e15360

University of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.

There is a need for alternatives to positive airway pressure for the treatment of obstructive sleep apnea and snoring. Improving upper airway dilator function might alleviate upper airway obstruction. We hypothesized that transoral neuromuscular stimulation would reduce upper airway collapse in concert with improvement in genioglossal muscle function. Read More

Cureus 2022 May 21;14(5):e25179. Epub 2022 May 21.

Department of Neuroscience, University of the East Ramon Magsaysay Memorial Medical Center, Quezon City, PHL.

Multifocal motor neuropathy (MMN) is a progressive, multifocal weakness, which typically begins and predominates in the upper extremities with the absence of a sensory deficit and a hallmark electrophysiologic finding of conduction block. We describe a case of an adult male with MMN who developed both cranial nerve involvement and vocal cord paralysis. The patient presented with left shoulder weakness without sensory loss followed by hoarseness of voice and later developed tongue deviation and wasting of the left sternocleidomastoid and left trapezius muscle. Read More

Am J Case Rep 2022 Jun 24;23:e936142. Epub 2022 Jun 24.

Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.

BACKGROUND Long arm (q) deletion syndrome of chromosome 18 is a congenital chromosomal disorder. The specialist dental management of patients with 18q deletion is a challenge, as these individuals fall into the category of patients with special needs. The aim of this work was to describe the surgical and dental management in hospital of a patient with long arm deletion syndrome of chromosome 18 (18q). Read More

Pathogens 2022 May 24;11(6). Epub 2022 May 24.

Oral Medicine and Periodontology Department, Faculty of Dentistry, The University of the Western Cape, Cape Town 7530, South Africa.

Syphilis is an infectious disease caused by Syphilis can present with an array of oral manifestations at different stages of disease progression. This article reports on four cases of syphilis with oral manifestations diagnosed by oral health professionals. Case 1: 18-year-old female presented with multiple ulcerations and patches involving the hard palate, uvula, retromolar area, and papillary nodules on the tongue. Read More

Molecules 2022 Jun 17;27(12). Epub 2022 Jun 17.

National Institutes for Food and Drug Control, Beijing 100050, China.

Rehd. et Wils. and Rehd. Read More

Medicina (Kaunas) 2022 May 28;58(6). Epub 2022 May 28.

Department of Public Oral Health, Program of Oral Health Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.

can be detected in subgingival sites of patients with periodontitis. However, the association between oral and periodontitis has not been fully elucidated in Japanese adults. The aim of this study is to clarify the relationship between oral infection/co-infection of oral and and periodontitis among middle-aged and older Japanese people. Read More

Foods 2022 Jun 15;11(12). Epub 2022 Jun 15.

Sichuan Tianwei Food Group Co., Ltd., Chengdu 610207, China.

Kinetic models and accelerated shelf-life testing were employed to estimate the shelf-life of Sichuan sauerkraut. The texture, color, total acid, microbe, near-infrared analysis, volatile components, taste, and sensory evaluation of Sichuan sauerkraut stored at 25, 35, and 45 °C were determined. Principal component analysis (PCA) and Fisher discriminant analysis (FDA) were used to analyze the e-tongue data. Read More

Biology (Basel) 2022 Jun 16;11(6). Epub 2022 Jun 16.

Department of Cell Biology, Histology and Embryology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.

The mammalian tongue plays a fundamental role in various physiological and behavioral activities. Significant morphological variations have been recorded in the tongue of several species. This study aims to obtain detailed histological and morphometric information about the filiform papillae on the surface of rat tongue. Read More

Cells 2022 Jun 11;11(12). Epub 2022 Jun 11.

Department of Animal Physiology, Biochemistry and Biostructure, Faculty of Veterinary Medicine and Animal Science, Poznan University of Life Sciences, Wołyńska 35, 60-637 Poznan, Poland.

The lingual mucosa in birds is covered with two specific types of multilayered epithelia, i.e., the para- and orthokeratinized epithelium, that differ structurally and functionally. Read More

Antibiotics (Basel) 2022 Jun 19;11(6). Epub 2022 Jun 19.

Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.

This study evaluates the effectiveness and safety of a microscale mist unit (MSM-UNIT) that sprays high-speed fine water droplets to remove dental plaque adhering to the oral mucosa (tongue and palate) and tooth surface. Fifteen patients who had difficulty self-managing sufficient oral care were included in this study. Effectiveness was evaluated for at least five patients' tongues, palate mucosas, and tooth surfaces, and safety evaluation was conducted at all three sites for all patients. Read More

Antibiotics (Basel) 2022 Jun 14;11(6). Epub 2022 Jun 14.

Department of Microbiology and Immunology, School of Dental Medicine, University of Belgrade, Dr Subotica 1, 11000 Belgrade, Serbia.

The subgingival biofilm, as the most complex microbial community, has been proven to be reservoir of spp. The main concept of this study was to investigate if there is a difference between the sensitivity of () isolated from tongue and subgingival areas of periodontitis patients to antifungal agents. The aim of the study was to determine: (1) the distribution of different species in the tongue and subgingival samples of periodontitis patients; (2) the susceptibility of strains from tongue and subgingival biofilm to the effects of commonly used antifungal agents: fluconazole, amphotericin B and itraconazole; (3) the correlation between the susceptibility of and clinical periodontal parameters. Read More

Antibiotics (Basel) 2022 May 31;11(6). Epub 2022 May 31.

Department of Urology and General Medicine, Faculty of Medicine, Medical University of Plovdiv, 15-A "Vasil Aprilov" Blvd, 4002 Plovdiv, Bulgaria.

Among the local factors for oral candidiasis, the piercing of the tongue is recognized by some authors as a risk factor for the colonization of . There are few case reports in which spp. colonization and infection are associated with tongue piercing but only one microbiological study supports this hypothesis in general. Read More

Animals (Basel) 2022 Jun 17;12(12). Epub 2022 Jun 17.

Zebrafish Neuromorphology Lab, Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.

A morphological study of the alimentary tract, from the oropharyngeal cavity to the rectum, including the attached glands, of African bony-tongue, (Cuvier, 1829) was carried out by gross anatomy, and light microscope analysis. This study aimed to give a deeper knowledge of the alimentary tract morphological features of this species of commercial interest. is distinguished by individual morphological characteristics showing a digestive tract similar to that of reptiles and birds. Read More

Food Chem 2022 Jun 14;394:133487. Epub 2022 Jun 14.

Beijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University (BTBU), Beijing 100048, China.

Currently, the effect of different pretreatments (i.e., radio frequency (RF), explosion puffing (EP), microwave (MW) and oven heating (OH)) on the flavor characteristics of peanut butter is unclear. Read More

Nano Lett 2022 Jun 23. Epub 2022 Jun 23.

School of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.

A novel biomimicked neuromorphic sensor for an energy efficient and highly scalable electronic tongue (E-tongue) is demonstrated with a metal-oxide-semiconductor field-effect transistor (MOSFET). By mimicking a biological gustatory neuron, the proposed E-tongue can simultaneously detect ion concentrations of chemicals on an extended gate and encode spike signals on the MOSFET, which acts as an input neuron in a spiking neural network (SNN). Such in-sensor neuromorphic functioning can reduce the energy and area consumption of the conventional E-tongue hardware. Read More

ACS Appl Mater Interfaces 2022 Jun 23. Epub 2022 Jun 23.

Chinese Academy of Sciences Key Laboratory of Bio-inspired Materials and Interface Sciences, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.

The key problem that hinders the water transportation performance and application of microchannels is the annoying gaslock. Realizing liquid transport without the gaslock requires a specially designed pump and a channel system, as well as the reduction of gas concentration in liquids. In nature, to eat viscous nectar with high efficiency, hummingbirds use their open geometric tongue for nectar-sucking. Read More

J Sleep Res 2022 Jun 22:e13673. Epub 2022 Jun 22.

Faculty of Medicine and health Sciences, University of Antwerp, Wilrijk, Belgium.

Mandibular advancement device (MAD) treatment outcome for obstructive sleep apnea (OSA) is variable and patient dependent. A global, clinically applicable predictive model is lacking. Our aim was to combine characteristics obtained during drug-induced sleep endoscopy (DISE), awake nasendoscopy, and computed tomography scan-based computational fluid dynamic (CFD) measurements in one multifactorial model, to explain MAD treatment outcome. Read More

Front Neurol 2022 6;13:900520. Epub 2022 Jun 6.

Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Motor dysfunction is common in patients with stroke. Acupuncture has become an acceptable alternative method for stroke rehabilitation. Previous studies have shown various functional connectivity changes activated by acupuncture. Read More

J Prosthodont Res 2022 Jun 22. Epub 2022 Jun 22.

Department of Dysphagia Rehabilitation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Purpose: This study aimed to investigate the relationship between tongue factors (tongue strength and tongue volume), systemic factors (grip strength and walking speed), and the extracellular water/total body water ratio.

Methods: This cross-sectional study included community-dwelling adults. Body water composition and skeletal muscle mass index were measured using bioelectrical impedance analysis. Read More

J Speech Lang Hear Res 2022 Jun 22:1-13. Epub 2022 Jun 22.

Swallowing Rehabilitation Research Laboratory, KITE, Toronto Rehabilitation Institute, University Health Network, Ontario, Canada.

Purpose: Patients with poststroke dysphagia may experience inefficient bolus clearance or inadequate airway protection. Following a stroke, impairments in lingual pressure generation capacity are thought to contribute to oropharyngeal dysphagia. The goal of our study was to determine whether similar profiles of swallowing impairment would be seen across a cohort of patients with reduced tongue strength within 3 months after cerebral ischemic stroke. Read More

MMW Fortschr Med 2022 Jun;164(12):26-27

Springer Medizin Verlag GmbH, Aschauer Str. 30, 81549, München, Deutschland.

Eur Arch Otorhinolaryngol 2022 Jun 22. Epub 2022 Jun 22.

Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), Paris, France.

Objective: The objective of this study was to investigate feasibility, surgical, oncological, and functional outcomes of transoral robotic cordectomy (TORS-Co) and whether TORS-Co reported comparable outcomes of transoral laser microsurgery (TLM).

Methods: PubMed, Scopus, and Cochrane Library were searched by three laryngologists for studies investigating feasibility, surgical, oncological, and functional outcomes of patients benefiting from TORS-Co. The following outcomes were investigated according to the PRISMA statements: age; cT stage; types of cordectomy; surgical settings; complications; and functional and feasibility features. Read More

Microb Genom 2022 Jun;8(6)

Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, Guangzhou, PR China.

Although characterization of the baseline oral microbiota has been discussed, the current literature seems insufficient to draw a definitive conclusion on the interactions between the microbes themselves or with the host. This study focuses on the spatial and temporal characteristics of the oral microbial ecosystem in a mouse model and its crosstalk with host immune cells in homeostasis. The V3V4 regions of the 16S rRNA gene of 20 samples from four niches (tongue, buccal mucosa, keratinized gingiva and hard palate) and 10 samples from two life stages (adult and old) were analysed. Read More

Sci Rep 2022 Jun 21;12(1):10438. Epub 2022 Jun 21.

Department of Family Medicine, Hsinchu MacKay Memorial Hospital, 690, Section 2, Guangfu Road, East District, Hsinchu City, 30071, Taiwan, ROC.

Tongue strengthening exercise (TSE) has been proposed as an intervention to increase tongue strength and improve swallowing. However, clinical evidence of its effectiveness is lacking. In this review, seven databases were searched from inception to September 30, 2021 for randomized controlled trials that compared tongue strengths between the TSE intervention and control groups, obtained from maximal tongue elevation peak force in kilopascals (kPa). Read More

Int J Oral Maxillofac Surg 2022 Jun 18. Epub 2022 Jun 18.

Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Tokyo, Japan.

The control of enclosed oral epithelial dysplasia is important for the control of oral cancer. Fluorescence visualization and iodine solution are able to detect oral epithelial dysplasia and surrounding oral cancer. The purpose of this study was to clarify the effectiveness of combining fluorescence visualization and iodine solution-guided surgery for early tongue cancer. Read More