Search Our Scientific Publications & Authors

J Bras Nefrol 2019 Mar 18. Epub 2019 Mar 18.

Serviço de Nefrologia e Transplantação Renal do Centro Hospitalar do Porto, Porto, Portugal.

The occurrence of ascites after Renal Transplant (RT) is infrequent, and may be a consequence of surgical or medical complications. Case report: 61 year-old, male, history of arterial hypertension, tongue carcinoma and alcoholic habits 12-20g/day. He had chronic kidney disease secondary to autosomal dominant polycystic kidney disease, without hepatic polycystic disease. Read More

Ir Med J 2019 Feb 14(2):878. Epub 2019 Feb 14.

King’s College Hospital NHS Foundation Trust, London, UK

Aesthetic Plast Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of Otorhinolaryngology, Baskent University Faculty of Medicine, 06490, Bahcelievler, Ankara, Turkey.

Background: A good understanding of nasal tip support mechanisms is essential for achieving successful and functional rhinoplasty results. The loss of nasal tip support resulting from different maneuvers adopted during rhinoplasty and how this loss is affected by reconstructive applications should be known. This study evaluated and compared changes in nasal tip support perioperatively after different techniques were used during septorhinoplasty. Read More

J Dent Sci 2018 Dec 29;13(4):374-377. Epub 2018 Aug 29.

Department of Oral and Maxillofacial Radiology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Background/purpose: In dentistry, panoramic radiography is an important examination technique. The Faculty of Dentistry at Tokushima University educates students about panoramic radiographic anatomical landmarks. The purpose of this study was to investigate differences in the understanding of each panoramic anatomical landmark among students. Read More

J Dent Sci 2018 Sep 19;13(3):182-183. Epub 2018 Jul 19.

Department of Clinical Specialistic and Dental Sciences, Marche Polytechnic University, Ancona, Italy.

J Dent Sci 2018 Mar 28;13(1):75-79. Epub 2013 Jun 28.

Oral Pathology Department, Faculty of Dentistry, Universidad Andrés Bello, Viña del Mar, Chile.

Alveolar soft-part sarcomas are clinically and morphologically distinct soft-tissue sarcomas, with an unknown histogenesis. When the tumors affect the region of the head and neck, they are often located in the orbit and tongue. We report a case of an alveolar soft-part sarcoma in the left masseter of a 28-year-old female. Read More

J Oral Facial Pain Headache 2019 Mar 20. Epub 2019 Mar 20.

Aims: To compare somatosensory function profiles and psychologic factors in patients with primary burning mouth syndrome (BMS) and healthy controls and to evaluate correlations of subjective pain ratings with somatosensory and psychologic parameters.

Methods: A quantitative sensory testing (QST) protocol-including cold detection threshold (CDT), warmth detection threshold (WDT), thermal sensory limen (TSL), paradoxical heat sensation (PHS), cold pain threshold (CPT), heat pain threshold (HPT), mechanical pain threshold (MPT), wind-up ratio (WUR), and pressure pain threshold (PPT)-was performed at the oral mucosa of the tongue, buccal, and palatal sites in 30 Chinese patients (25 women and 5 men, mean age 50.9 ± 9. Read More

J Oral Rehabil 2019 Mar 20. Epub 2019 Mar 20.

Department of Dentistry and Oral Health, Section for Orofacial Pain and Jaw Function, Arhus University.

Burning mouth syndrome (BMS) is a chronic orofacial pain disorder of unknown cause. It is more common in peri- and postmenopausal women, and sex hormone dysregulation is believed to be an important causative factor. Psychosocial events often trigger or exacerbate symptoms, and persons with BMS appear to be predisposed toward anxiety and depression. Read More

Animal Model Exp Med 2018 Jun 28;1(2):143-151. Epub 2018 Jul 28.

Department of Laboratory Animal Science Shanghai Public Health Clinical Center Fudan University Shanghai China.

Background: Lingual epithelia in the tongue tip are among the most rapidly regenerating tissues, but the mechanism of cell genesis in this tissue is still unknown. Previous study has suggested the existence of multiple stem cell pools in lingual epithelia and papillae. Like K14+ and Sox2+ cells, NTPDase2+ cells have characteristics of stem cells. Read More

Int J Parasitol Parasites Wildl 2019 Apr 23;8:188-191. Epub 2019 Feb 23.

College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, PR China.

has been found to infect almost all warm-blooded animals; however, some hosts lack direct evidence of infection. The red panda () is an endangered species that mainly lives in temperate forests of South Asia. Here, infection in red pandas from zoos in China were reported. Read More

Cureus 2018 Dec 11;10(12):e3720. Epub 2018 Dec 11.

Cardiology, Saint Vincent Hospital, Worcester, USA.

Dual antiplatelet therapy (DAPT) is widely recognized as the mainstay of treatment after percutaneous coronary intervention (PCI). Premature discontinuation may pose a risk of in-stent thrombosis, acute myocardial infarction, and death. With the increased usage of antiplatelet agents, increased attention has been drawn to their potential allergic reactions. Read More

Front Neurol 2019 5;10:170. Epub 2019 Mar 5.

School of Dentistry, University of Siena, Siena, Italy.

The aim is to describe the process of translating the smartphone application into Polish within the context of an ongoing multicenter project on awake bruxism (AB) epidemiology. An ongoing cooperation involving 11 universities is based on the adoption of the smartphone-based EMA protocol to collect real time report of AB behaviors in the natural environment. The English version of is adopted as a template for the multi-language translation, according to a step-by-step procedure led by mother-tongue experts in the field. Read More

Sensors (Basel) 2019 Mar 18;19(6). Epub 2019 Mar 18.

Institute of Chemistry, Saint-Petersburg State University, Universitetskaya emb., 7-9-11, 199304 Saint-Petersburg, Russia.

Currently, there are no established procedures for limit of detection (LOD) evaluation in multisensor system studies, which complicates their correct comparison with other analytical techniques and hinders further development of the method. In this study we propose a simple and visually comprehensible approach for LOD estimation in multisensor analysis. The suggested approach is based on the assessment of evolution of mean relative error values in calibration series with growing analyte concentration. Read More

Laryngoscope 2019 Mar 19. Epub 2019 Mar 19.

Department of Neurology, Jose R. Reyes Memorial Medical Center, Manila, Philippines.

Objectives: To systematically characterize and describe voice and swallowing manifestations in patients with X-linked dystonia parkinsonism (XDP) and correlate with quality-of-life (QOL) measures.

Methods: Thirty-four patients with XDP with communication and swallowing difficulties underwent neurological examination, head and neck examination, nasopharyngoscopy, QOL surveys (Swallowing Quality of Life questionnaire [SWAL-QOL] and Voice Handicap Index [VHI]), and functional endoscopic evaluation of swallowing (FEES) to assess the extent of dysfunction.

Results: All patients showed high rates of lingual, oromandibular, and laryngeal dysfunction, as well as severe QOL changes in swallowing and communication ability. Read More

Clin Toxicol (Phila) 2019 Mar 19:1-3. Epub 2019 Mar 19.

c Clinical Toxicology and Environmental Biomonitoring Lab, University of California, San Francisco , San Francisco , CA, USA.

Context: Fentanyl analogs are synthetic opioids that bind to mu receptors with high potency. We report two cases where users developed apnea and required naloxone reversal after exposure to small quantities of the fentanyl analogs, furanylfentanyl and ß-hydroxyfentanyl.

Case Details: A 19 year-old woman reported insufflating a small number of granules of "fentanyl" powder and developed apnea. Read More

Analyst 2019 Mar 19. Epub 2019 Mar 19.

São Carlos Institute of Physics, University of São Paulo, CP 369, 13560-970, São Carlos, Brazil.

This work reports on a low cost microfluidic electronic tongue (e-tongue) made with carbon interdigitated electrodes, printed on paper, and coated with boronic acid-containing hydrogels. Using capacitance measurements, the e-tongue was capable of distinguishing between different types of sugars (e.g. Read More

Eur Arch Otorhinolaryngol 2019 Mar 18. Epub 2019 Mar 18.

Department Otorhinolaryngology-Head and Neck Surgery, Busan Saint Mary's Hospital, 538-41 Yongho-dong, Nam-gu, Busan, South Korea.

Purpose: An ideal, drug-induced sleep endoscopy (DISE) classification system should cover all the upper airways, be simple and practical, and quantify the severity of any obstruction. Excellent validity and reliability are essential. We explored the inter-rater reliability of Koo's DISE classification system in the hands of experienced and inexperienced otolaryngologists. Read More

J Cutan Aesthet Surg 2018 Oct-Dec;11(4):245-247

Department of Dermatology, Mazandaran University of Medical Sciences, Sari, Iran.

A young otherwise healthy male presented with asymptomatic pinkish-red nodule over postero-lateral tongue with the suspicion of having developed oral cancer. Biopsy from the lesion showed multiple circumscribed nodules in the lamina propria comprised of numerous oval and spindle-shaped cells. Abundant lymphatic tissue with germinal centres were also observed. Read More

Clin Cancer Res 2019 Mar 18. Epub 2019 Mar 18.

Sun Yst-sen Memorial Hospital, Sun Yat-sen University

Purpose: The overall biological roles and clinical significance of most long noncoding RNAs(lncRNAs) in chemosensitivity are not fully understood. We investigated the biological function, mechanism and clinical significance of lncRNA NR_034085, which we termed miRNA processing related lncRNA(MPRL), in tongue squamous cell carcinoma(TSCC).

Experimental Design: LncRNA expression in TSCC cell lines with cisplatin treatment was measured by lncRNA microarray and confirmed in TSCC tissues. Read More

Oral Oncol 2019 Mar 15. Epub 2019 Mar 15.

Department of Otolaryngology, Loyola University Medical Center, Maywood, IL, United States.

Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder characterized by mutations of mismatch repair genes leading to the early development of multiple malignancies. The most common malignancy is colorectal cancer but there is a strong association with malignancies of the ovary, endometrium, small intestine, stomach, skin, brain, and pancreas. We report a case of a 35-year-old female with a history of known HNPCC who presented with adenocarcinoma of the small intestine as well as a synchronous oral tongue squamous cell carcinoma. Read More

Clin Ther 2019 Mar 15. Epub 2019 Mar 15.

ALK Abelló A/S, Hørsholm, Denmark. Electronic address:

Purpose: Efficient delivery of allergens to the sublingual mucosa is a prerequisite for successful sublingual immunotherapy (SLIT) for allergy, and in order to become available to immune-competent cells embedded in the sublingual mucosa, allergens need to be delivered in a soluble form. Delivery of solubilized allergens poses a particular challenge for tablet-based allergy immunotherapy, in which allergens are administered under the tongue in the form of dry tablets and need to be dissolved rapidly in a small volume of saliva, with little or no agitation. The purposes of this article were to compare the properties of 2 different pharmaceutical SLIT-tablet formulations, freeze-dried and compressed, and to examine how the tablet formulation affects the efficiency with which allergen is delivered from the dry state of the tablet into soluble form. Read More

Int J Mol Sci 2019 Mar 16;20(6). Epub 2019 Mar 16.

Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA.

The Hedgehog (Hh) pathway has regulatory roles in maintaining and restoring lingual taste organs, the papillae and taste buds, and taste sensation. Taste buds and taste nerve responses are eliminated if Hh signaling is genetically suppressed or pharmacologically inhibited, but regeneration can occur if signaling is reactivated within the lingual epithelium. Whereas Hh pathway disruption alters taste sensation, tactile and cold responses remain intact, indicating that Hh signaling is modality-specific in regulation of tongue sensation. Read More

PLoS One 2019 18;14(3):e0213851. Epub 2019 Mar 18.

Department of Linguistics and Research Focus Cognitive Sciences, University of Potsdam, Potsdam, Brandenburg, Germany.

The speed-curvature power law is a celebrated law of motor control expressing a relation between the kinematic property of speed and the geometric property of curvature. We aimed to assess whether speech movements obey this law just as movements from other domains do. We describe a metronome-driven speech elicitation paradigm designed to cover a wide range of speeds. Read More

J Craniofac Surg 2019 Mar 12. Epub 2019 Mar 12.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung.

A thyroglossal duct cyst (TGDC) is a common embryological remnant that typically presents as an anterior neck mass; however, this malformation can occur in any adjacent area, including the tongue base (lingual type), along the migration path of the thyroid during embryonic development. Lingual TGDC is often quiescent until infection occurs. Supraglottitis or inflammation of the supraglottis, is a potentially life-threatening disease. Read More

Front Cell Infect Microbiol 2019 1;9:39. Epub 2019 Mar 1.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.

The oral microbiome has the potential to provide an important symbiotic function in human blood pressure physiology by contributing to the generation of nitric oxide (NO), an essential cardiovascular signaling molecule. NO is produced by the human body via conversion of arginine to NO by endogenous nitric oxide synthase (eNOS) but eNOS activity varies by subject. Oral microbial communities are proposed to supplement host NO production by reducing dietary nitrate to nitrite via bacterial nitrate reductases. Read More

Plast Reconstr Surg Glob Open 2018 Nov 7;6(11):e1973. Epub 2018 Nov 7.

Division of Plastic and Reconstructive Surgery, Children's National Medical Center, Washington, D.C.

Background: Robin sequence is defined by the clinical triad of micrognathia, glossoptosis, and upper airway obstruction, and is frequently associated with cleft palate and failure to thrive. Though the efficacy of certain surgical interventions to relieve airway obstruction has been well established, algorithms dictating decision making and perioperative protocols are poorly defined.

Methods: A 22-question survey was sent via e-mail to members of the American Cleft Palate-Craniofacial Association and International Society of Craniofacial Surgeons. Read More

Plast Reconstr Surg Glob Open 2018 Nov 13;6(11):e1937. Epub 2018 Nov 13.

Division of Plastic & Reconstructive Surgery, Stanford University. Stanford, CA.

Tessier #30 clefts (median mandibular clefts) represent a spectrum of deformities ranging from a minor cleft in the lower lip to complete clefts of the mandible involving the tongue, lower lip, hyoid bone, thyroid cartilages, and manubrium. Various techniques have been used to address these problems; the most common procedure involving 2 stages: an initial correction of the soft tissue followed by closure of the mandibular cleft at a later date using bone grafting. This approach was subsequently reduced to a single operation, but still required harvesting of autologous bone graft. Read More

Ther Clin Risk Manag 2019 25;15:309-313. Epub 2019 Feb 25.

ENT Department, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania,

Background: The rigid tube for laryngoscopy is an instrument used in ENT, for inspecting the larynx and its vicinity. We used it to facilitate intubation, in ENT patients.

Methods: Twenty patients attending for surgery were included for study. Read More

Acta Orthop Belg 2018 Dec;84(4):469-478

Displaced calcaneus fracture often results in severe permanent sequelae and considerably limits the activities of daily living. In this prospective cohort study we present the outcomes of surgical treatment of 137 displaced intra-articular calcaneal fractures, over 8y period. Follow-up data were obtained up to 3 years post-operatively. Read More

Integr Cancer Ther 2019 Jan-Dec;18:1534735419833795

1 Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.

5-Fluorouracil (5-FU) is used in the treatment of head and neck cancer patients. However, adverse effects experienced such as mucositis and poor appetite may lead to interruption in chemotherapy. The aim of this study is to evaluate the efficacy of GMI, one fungal immunomodulatory protein found in Ganoderma microsporum, for mucositis induced by 5-FU in a mouse model. Read More

Amyotroph Lateral Scler Frontotemporal Degener 2019 Mar 18:1-3. Epub 2019 Mar 18.

a Department of Neurology , Greater Manchester Neurosciences Centre, Salford Royal Foundation Trust , Salford , UK.

Fused in sarcoma-related amyotrophic lateral sclerosis (FUS-ALS) accounts for 4% of all familial motor neurone disease, but has a much higher incidence in juvenile ALS. We present a case of a 17-year-old British man with rapidly progressive bulbar and respiratory failure. On examination he had weak periocular muscles, neck flexion weakness, and a wasted, fasciculating and weak tongue. Read More

Hell J Nucl Med 2019 Jan-Apr;22 Suppl:133-146

1st Otolaryngology Dept, Medical School, Aristotle University of Thessaloniki, Aristotle University Campus, 54124, Thessaloniki, Greece.

Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease that belongs to the group of motor neuron diseases. Motor deficits like reduce in tongue strength, may coexist with cognitive deficits compatible with frontotemporal dementia (FTD), also known as frontotemporal lobar degeneration (FTLD). FTD is a neurodegenerative syndrome with two main clinical variants: behavioral (bvFTD) and language or Primary Progressive Aphasia (PPA). Read More

Int J Oral Maxillofac Surg 2019 Mar 12. Epub 2019 Mar 12.

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.

The lingual lymph nodes (LLNs) can only be detected with difficulty in early-stage tongue squamous cell carcinomas owing to the small size. Recurrence or metastasis could occur in the floor of the mouth as a result of neglecting the LLNs. The injection of carbon nanoparticles to track occult LLNs in early-stage tongue squamous cell carcinoma is presented and discussed. Read More

Int J Oral Maxillofac Surg 2019 Mar 12. Epub 2019 Mar 12.

Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Nuclear protein of the testis (NUT) midline carcinomas (NMC) are malignant epithelial tumours that have chromosomal rearrangements of the gene encoding NUT at 15q14. NMC is typically an aggressive fatal cancer, clinically overlaps with other carcinomas, and differential diagnosis is difficult. The purpose of this study was to investigate NMC in poorly differentiated oral squamous cell carcinoma (OSCC) with a retrospective analysis based on anti-C52B1 immunohistochemical staining. Read More

J Voice 2019 Mar 12. Epub 2019 Mar 12.

Department of Otorhinolaryngology/Phoniatrics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.

Introduction: Laryngeal and pharyngeal activity during inner singing is discussed in the context of vocal hygiene. Inner singing is defined as imagined singing, reading music silently, and listening to vocal music. When vocal rest is prescribed, doctors, speech therapists, and voice pedagogues recommend avoiding listening to music or reading music silently, since it is suggested that inner singing unconsciously influences the glottis, and thus moves the vocal folds involuntarily. Read More

Neoplasia 2019 Mar 12;21(4):376-388. Epub 2019 Mar 12.

Department of Oral Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263; Department of Dentistry and Maxillofacial Prosthetics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263. Electronic address:

The anticancer activity of 1,25-dihydroxyvitamin D3 (1,25(OH)D or calcitriol) has been widely reported in preclinical models. However, systematic investigation into the chemopreventive potential of calcitriol against the spectrum of oral carcinogenesis has not been performed. To address this gap in knowledge, we conducted a preclinical prevention trial of calcitriol in the 4-nitroquinoline-1-oxide (4NQO) oral carcinogenesis model. Read More

J Oral Implantol 2019 Mar 15. Epub 2019 Mar 15.

3 Long Island Jewish Medical Center Dental medicine Kings County Hospital Center. Currently Long Island Jewish Medical Center.

The tongue flap is a hardy flap that is routinely utilized by oral and maxillofacial surgeons to cover intraoral defects. It has not been described as a method for keratinized soft tissue coverage in conjunction with dental implant placement. In this article, we use the tongue flap in the closure of a chronic anterior maxillary dehiscence and to provide keratinized soft tissue coverage for anterior dental implants. Read More

HNO 2019 Mar 14. Epub 2019 Mar 14.

Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Klinikum rechts der Isar, der Technischen Universität München, Ismaninger Str. 22, 81675, München, Deutschland.

Upper airway stimulation plays an increasingly important role in the treatment of obstructive sleep apnea (OSA). The target of stimulation is the hypoglossal nerve (N. XII), which-as a pure motor nerve-innervates the intrinsic and extrinsic tongue muscles. Read More

Hautarzt 2019 Mar 12. Epub 2019 Mar 12.

Hautklinik, Städtisches Klinikum Karlsruhe, Akademisches Lehrkrankenhaus der Universität Freiburg, Moltkestr. 120 (Gebäude V), 76133, Karlsruhe, Deutschland.

Am Fam Physician 2019 Mar;99(6):385-386

U.S. Naval Hospital, Tutuhan, Guam.

J Anim Sci 2019 Mar 15. Epub 2019 Mar 15.

School of Psychology, Cardiff University, Cardiff, UK.

Despite the importance of hedonic reactions in pig's intake, feed palatability has been typically inferred from preference or acceptance measures. However, these measures are influenced by factors beyond palatability, such as energy density and hunger. The aim of this study was to evaluate palatability responses in pigs to sweet and umami taste at different inclusions levels. Read More

World J Plast Surg 2019 Jan;8(1):103-107

Department of Oral- Maxillo-Facial Surgery, Plastic Operations, Dietrich-Bonhoeffer-Klinikum Neubrandenburg, Germany.

Head and neck squamous cell carcinoma (HNSCC) is the most frequent carcinoma of the head and neck region. For coverage of an entire resected mandible with floor of the mouth, 3/4 of the tongue and soft tissue of cheeks and neck bony reconstruction of the mandible and soft tissue reconstruction of tongue, cheeks and a neck large flap are needed. A patient with a superinfected T4 HNSCC was presented to our outpatient clinic. Read More

Sci Rep 2019 Mar 14;9(1):4574. Epub 2019 Mar 14.

Department of Endodontics, University of Texas Health at San Antonio, San Antonio, TX, USA.

Considerable gap in knowledge exists about the mechanisms by which oral tumors regulate peripheral sensory fibers to produce pain and altered sensations. To address this gap, we used a murine model of oral squamous cell carcinoma (OSCC) of the tongue to investigate changes in response properties of trigeminal afferent neurons. Using this model, we developed an ex vivo method for single neuron recordings of the lingual nerve from isolated tongue tissue. Read More

Neurobiol Dis 2019 Mar 12;127:242-252. Epub 2019 Mar 12.

School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK. Electronic address:

Niemann-Pick type C disease (NPCD) is a neurodegenerative disease associated with increases in cellular cholesterol and glycolipids and most commonly caused by defective NPC1, a late endosomal protein. Using ratiometric probes we find that NPCD cells show increased endolysosomal pH. In addition U18666A, an inhibitor of NPC1, was found to increase endolysosomal pH, and the number, size and heterogeneity of endolysosomal vesicles. Read More

Neurosci Biobehav Rev 2019 Mar 11;100:211-223. Epub 2019 Mar 11.

University of Helsinki, Helsinki Collegium for Advanced Studies, P.O. Box 4 (Fabianinkatu 24), FIN 00014, Finland; Perception, Action & Cognition Research Group, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00014, Finland; Phonetics and Speech Synthesis Research Group, Department of Digital Humanities, University of Helsinki, Unioninkatu 40, 00014, Finland. Electronic address:

Mounting evidence shows interaction between manipulative hand movements and movements of tongue, lips and mouth in a vocal and non-vocal context. The current article reviews this evidence and discusses its contribution to perspectives of development and evolution of speech. In particular, the article aims to present novel insight on how processes controlling the two primary grasp components of manipulative hand movements, the precision and power grip, might be systematically connected to motor processes involved in producing certain articulatory gestures. Read More

J Dent Child (Chic) 2018 Sep;85(3):147-150

Assistant professor, Department of Oral Pathology, in the Centre for Dental Education and Research, at the India Institute of Medical Sciences, New Delhi, India.

The tongue is a muscular organ with a rich blood supply and acts as an immune defence mechanism. The occurrence of a tongue abscess without immune deficiency is rare. The purpose of this report is to present the case of an eight-year-old boy with a spherical, pinkish-yellow, fluctuant, nontender swelling measuring two cm in diameter on the right anterolateral border of the tongue, causing difficulty in swallowing and speaking. Read More

J Histochem Cytochem 2019 Mar 14:22155419836433. Epub 2019 Mar 14.

Division of Life Science, Meiji University, Kanagawa, Japan.

Neuronatin ( Nnat) is expressed in the pituitary, pancreas, and other tissues; however, the function of NNAT is still unclear. Recent studies have demonstrated that NNAT is localized in the sex-determining region Y-box 2-positive stem/progenitor cells in the developing rat pituitary primordium and is downregulated during differentiation into mature hormone-producing cells. Moreover, NNAT is widely localized in subcellular organelles, excluding the Golgi. Read More

J Oral Rehabil 2019 Mar 14. Epub 2019 Mar 14.

Department of Gerodontology, Division of Gerontology and Gerodontology, Tokyo Medical and Dental University, Tokyo, Japan.

Background: The tongue plays an important role during the oropharyngeal phase of swallowing. Each part of the tongue has a different function during swallowing. Aging causes changes in muscle quantity and quality. Read More

Zhongguo Zhong Yao Za Zhi 2019 Jan;44(1):112-118

Institute of Basic Medical Sciences,Xiyuan Hospital,China Academy of Chinese Medical Sciences Beijing 100091,China.

This research was aimed to evaluate the protective effect and potential mechanism of Yiqi Tongluo Particles(YQTLs).Firstly,an animal model of multiple cerebral infarction(MCI) with Qi deficiency and blood stasis was established.Rats were randomly divided into six groups:SHAM group,Vehicle group,Buyang Huanwu decoction original group(BYHWO),EGb761 group,high and low dose of YQTLs group. Read More

Am J Med Genet A 2019 Mar 13. Epub 2019 Mar 13.

Department of Pediatrics and Medical Genetics, Medical University, Plovdiv, Bulgaria.

Andermann syndrome (AS) is caused by mutation of SLC12A6 gene. It comprises severe progressive sensory and motor neuropathy with early onset, varying degree of agenesis of corpus callosum (ACC) and mental retardation. AS occurs occasionally among population outside the northeastern Quebec-Saguenay-Lac- St-Jean and Charlevoix regions, inhabited by French Canadians. Read More