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Proc (Bayl Univ Med Cent) 2022 3;35(3):391-393. Epub 2022 Mar 3.

Department of Oral and Maxillofacial Surgery, Baylor University Medical Center and Texas A&M College of Dentistry, Dallas, Texas.

Ameloblastomas are benign, locally invasive odontogenic tumors that comprise approximately 1% of tumors within the jaws, with 66% located in the posterior mandible. If left untreated, these lesions can reach enormous size, resulting in considerable deformity and associated morbidity. Traditionally, defects >6 cm warranted a free-flap fibula transfer or iliac crest autogenous graft. Read More

Oper Orthop Traumatol 2022 Jun 29;34(3):239-252. Epub 2021 Nov 29.

Abteilung für Orthopädie und Traumatologie, Landesklinikum Baden-Mödling, Sr. M. Restituta-Gasse 12, 2340, Mödling, Österreich.

Objective: Open treatment of osteochondral defects of the knee to fully restore the bony defect and the articular surface.

Indications: Focal, symptomatic osteochondral lesions of the knee with a depth of ≥ 5 mm and a surface of ≥ 1.5 cm. Read More

Plast Reconstr Surg Glob Open 2021 Nov 22;9(11):e3881. Epub 2021 Nov 22.

Department of Plastic and Hand Surgery, Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nürnberg FAU, Germany.

This study presents a novel surgical technique for the reconstruction of highly challenging large lower back defects. In this case, a 72-year-old man initially diagnosed with renal cell carcinoma received nephrectomy followed by the dissection of an iliac crest metastasis and repeated high-dose irradiation therapy. Several years later, an osteocutaneous fistula at the right caudal posterior trunk made the reconstruction of the lower back defect necessary. Read More

Ann Plast Surg 2021 12;87(6):e129-e136

JMS Burn and Reconstruction Center, Jackson, MS.

Background: Osteonecrosis of the femoral head (ONFH) often affects young, active patients, and the femoral head's preservation is the primary goal of treatment for this disease. Vascularized iliac crest bone grafting is one of the many vascularized procedures used in treating ONHF. In some cases, we selectively performed this procedure using the musculoperiosteal iliac flap with the ascending branch of the lateral femoral circumflex artery for ONFH treatment. Read More

Microsurgery 2022 Jan 7;42(1):84-88. Epub 2021 Oct 7.

Department of Plastic Surgery, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.

Partial maxillectomy for maxillary sinus cancer treatment requires soft tissue reconstruction with enough bulk to occupy the large-volume defect. Deep inferior epigastric artery-based flaps and subscapular artery-based flaps are commonly used, but necessitate invasive muscle dissection or position change and a large recipient vessel. The aim of this report was to present a case of partial maxillectomy defect successfully reconstructed with a superficial circumflex iliac artery (SCIA) perforator (SCIP) flap, to address these drawbacks. Read More

Plast Reconstr Surg Glob Open 2021 Oct 4;9(10):e3846. Epub 2021 Oct 4.

Illawarra Shoalhaven Local Health District, Wollongong Hospital, Wollongong, New South Wales, Australia.

Information about the use and donor site morbidity of periosteal free flaps in head and neck reconstruction is limited. The aim of this study was to examine potential periosteal free flap donor sites with respect to their dimensions, tissue and pedicle characteristics, and predicted donor site morbidity in a cadaveric model. The following cadaveric periosteal specimens with a vascular pedicle were harvested using standard surgical approaches: skull, chest wall, sternum, scapula, iliac crest, femur, and humerus. Read More

Mol Pharm 2021 07 10;18(7):2556-2573. Epub 2021 Jun 10.

Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 111, Taiwan.

Cyclo-(D-Trp-Tyr) peptide nanotubes (PNTs) were reported to be potential carriers for oral gene delivery in our previous study; however, the effect of the aspect ratio (AR) of these PNTs on gene delivery could affect penetration or interception in biological environments. The aim of this study was to assess the feasibility of cyclo-(D-Trp-Tyr) PNTs with two ARs as carriers for oral pMBP-bcl-x- delivery to the spinal cord to treat spinal cord injury (SCI). We evaluated the biodistribution of oligodendrocyte (OLG)-specific myelin basic protein gene promoter-driven antiapoptotic DNA (pMBP-bcl-x) to the brain and spinal cord delivered with cyclo-(D-Trp-Tyr) PNTs with large (L) and small (S) PNTs with two ARs. Read More

J Plast Reconstr Aesthet Surg 2021 02 20;74(2):259-267. Epub 2020 Sep 20.

Assistance Publique - Hôpitaux de Paris, Service de Chirurgie Maxillo-faciale et Stomatologie, Hôpital Beaujon, Université de Paris, Paris, France.

Primary mandibular reconstruction after tumor removal or osteoradionecrosis treatment is a standard procedure. The most common reconstruction techniques are fibula, scapula, and iliac crest free flaps. Nevertheless, all patients are not eligible for microsurgery. Read More

JBJS Essent Surg Tech 2020 Jan-Mar;10(1). Epub 2020 Mar 23.

Vienna Shoulder & Sports Clinic, Vienna, Austria.

Anterior shoulder instability is commonly associated with injuries to the labrocapsular structures of the glenohumeral joint and with osseous glenoid defects of varying degree. If the bone defect exceeds a clinically relevant threshold, mere soft-tissue repairs result in high rates of recurrent instability and the glenoid needs to be reconstructed with osseous augmentation. The most popular techniques for glenoid reconstruction include variations of coracoid transfer or bone-block procedures; however, these procedures are not free from risks and complications, which are often related to the method of fixation. Read More

Ann Plast Surg 2020 05;84(5S Suppl 3):S235-S240

From the Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.

Background And Objective: The management of bone defects is still a difficult problem. Local vascularized bone grafts represent an efficient and widely used method. In this retrospective report, iliac bone flaps of the ascending branch of the lateral circumflex femoral artery were used for the management of proximal femur bone defects. Read More

Int J Spine Surg 2020 Feb 10;14(Suppl 1):3-13. Epub 2020 Feb 10.

Engineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Orthopaedics, The University of Toledo, Toledo, Ohio.

Background: The sacroiliac joints (SIJs), the largest axial joints in the body, sit in between the sacrum and pelvic bones on either side. They connect the spine to the pelvis and thus facilitate load transfer from the lumbar spine to the lower extremities. The majority of low back pain (LBP) is perceived to originate from the lumbar spine; however, another likely source of LBP that is mostly overlooked is the SIJ. Read More

Microorganisms 2019 Nov 18;7(11). Epub 2019 Nov 18.

Departamento de Anatomía Patológica del Nuevo Hospital Civil de Guadalajara, Salvador Quevedo y Zubieta 750, Independencia Oriente, Guadalajara 44340, Mexico.

Chronic infection with the intracellular parasite produces an accumulation of cysts in the brain and muscle, causing tissue damage. The cysts in the brain motor regions affect some kinematic locomotion parameters in the host. To localize the brain cysts from and study the changes in kinematic locomotion in C57BL/6 mice. Read More

J Clin Orthop Trauma 2019 Oct 14;10(Suppl 1):S231-S233. Epub 2018 Dec 14.

Department of Trauma and Emergency, AIIMS Bhubaneswar, Sijua, Patrapada, Odisha, 751019, India.

Defect in the lateral malleolus along with lateral ligamentous injury of ankle is rare. It occurs mainly due to resection of distal fibula tumors and severe trauma leading to loss of lateral malleolus. Lateral malleoli has the major contribution in weight transmission to foot and ankle stability. Read More

Arch Orthop Trauma Surg 2019 Oct 18;139(10):1417-1424. Epub 2019 Jul 18.

Department of Rheumatology and Arthroscopy, Marienkrankenhaus Düsseldorf-Kaiserswerth, An St Swidbert 17, Düsseldorf, Germany.

Aim: The subscapularis muscle is an important active stabilizer of the glenohumeral joint. For this radiological study, we investigated if its radiological integrity is affected after arthroscopic glenoid reconstruction. In the technique used, an autologous iliac crest graft is transported through the rotator interval, and the graft is fixed via an antero-inferior portal with compression screws. Read More

Arch Orthop Trauma Surg 2019 Oct 18;139(10):1435-1444. Epub 2019 Jun 18.

Department of Shoulder and Elbow Surgery, Center for Musculoskeletal Surgery (CMSC), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

Background: The coracoid transfer represents a treatment option for patients with recurrent shoulder instability. Only a few studies exist about the complication rate of the coracoid transfer as a revision surgery following failed soft tissue stabilization. The purpose of this study was to analyze the results and complication rate after coracoid transfer as a revision surgery. Read More

J Ayub Med Coll Abbottabad 2019 Apr-Jun;31(2):156-161

Department of Plastic Surgery, Shifa International Hospital, Islamabad, Pakistan.

Background: Free tissue transfer is a routine practice in adults with good success rates. Further advances in techniques and microsurgical skills have proved that free tissue transfer in paediatric population is feasible, reliable and safe.

Methods: This study is conducted to compare anastomosis duration, total general anaesthesia duration, hospital stay and outcomes of flaps (survival, partial loss, complete loss, complications) in paediatric group (age <15 years) and adult group (15-70 years age). Read More

Eur Rev Med Pharmacol Sci 2019 Apr;23(2 Suppl):12-18

Orthopedic Department, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.

Clinical management of a septic non-union of the distal humerus is challenging and is complicated by the diversity of potential treatments which are variably successful. We report a novel and very successful treatment of a 58-year-old man presenting an infected non-union of the right distal humerus, secondary to a closed fracture initially treated with two anatomic plates. After hardware removal, a two-stage reconstruction was performed. Read More

Int Orthop 2019 11 15;43(11):2601-2605. Epub 2019 Jan 15.

Paley Orthopedic and Spine Institute, St. Mary's Hospital, West Palm Beach, FL, 33407, USA.

Purpose: Stump overgrowth is the main problem of limb amputation in children. Many surgical procedures have been developed to overcome the problem, but all have shown inconsistent results. The only surgical procedure that has been successful in preventing overgrowth is capping of the amputated limb with a cartilaginous cap taken from the amputated limb, usually from the head of fibula. Read More

Cureus 2018 Oct 10;10(10):e3437. Epub 2018 Oct 10.

Otolaryngology, Aga Khan University Hospital, Karachi, PAK.

Introduction Ameloblastoma is a locally destructive tumor with a propensity for recurrence if not entirely excised. Management of ameloblastoma poses a challenge for all involved in the field of head and neck surgery because successful treatment requires not only adequate resection but also a functional and aesthetically acceptable reconstruction of the residual defect. Methods Patients who had histologically proven ameloblastoma between 1991 and 2009 were identified from the database of Aga Khan University Hospital. Read More

Spine Deform 2018 Sep - Oct;6(5):498-506

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 W. Thomas Rd., Phoenix, AZ 85013, USA. Electronic address:

Study Design: Cadaveric feasibility study and case report.

Objective: To determine if it is feasible to rotate pedicled vascularized bone graft (VBG) from L1 to S1 via a posterior approach.

Summary Of Background Data: VBG has been used to successfully augment fusion rates in various skeletal pathologies. Read More

Otolaryngol Head Neck Surg 2019 01 24;160(1):100-106. Epub 2018 Jul 24.

1 Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Objective: This study evaluated the accuracy of the Surgical Risk Calculator (SRC) of the ACS NSQIP (American College of Surgeons National Surgical Quality Improvement Program) in predicting head and neck microvascular reconstruction outcomes.

Study Design: Retrospective analysis.

Setting: Tertiary medical center. Read More

Orthop Traumatol Surg Res 2018 10 7;104(6):911-915. Epub 2018 Jun 7.

Service de chirurgie orthopédique et traumatologique, CHU de Maison-Blanche, 45, rue Cognacq-Jay, 51092 Reims cedex, France. Electronic address:

Introduction: Management of septic non-union of the tibia requires debridement and excision of all infected bone and soft tissues. Various surgical techniques have been described to fill the bone defect. The "Induced Membrane" technique, described by A. Read More

J Reconstr Microsurg 2018 Nov 12;34(9):719-728. Epub 2018 May 12.

Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Background:  The superficial circumflex iliac artery (SCIA)-based iliac bone flap has yet to be widely used. The purpose of this article is to validate the feasibility of SCIA-based iliac bone flap transfers for reconstruction of small to moderate-sized bony defects. Retrospective outcome comparisons between SCIA-based iliac bone flaps and fibula flaps were made. Read More

Aust Dent J 2018 03;63 Suppl 1:S108-S113

Royal Brisbane and Women's Hospital, University of Queensland, Herston Qld, Australia.

Prosthetic replacements in the 19th and early 20th century were superseded by pedicled flaps and obturators. These have subsequently been superseded by free tissue transfer which currently is the mainstay of reconstructive jaw surgery. Although malignant and benign processes of the jaws are the predominant cause of segmental defects, a significant proportion still occurs due to trauma, or even iatrogenic causes such as radiotherapy. Read More

Microsurgery 2018 Nov 7;38(8):882-888. Epub 2017 Dec 7.

JMS Burn and Reconstructive Center, Jackson, Mississippi.

Purpose: We present the results of a study on the anatomy of the ascending branch of the lateral circumflex femoral artery (AB-LCFA) and the use of the pedicled iliac bone flap transfer perfused by AB-LCFA combined with external fixation for the treatment of the nonunion of upper femoral shaft fractures.

Methods: The orientation, diameter, length, and distribution of the AB-LCFA from 40 lower limbs of adult cadavers were dissected and measured. From 2000 to 2012, 13 patients with nonunion of upper femoral shaft fractures underwent pedicled iliac bone flap transfer perfused by the AB-LCFA combined with external fixation. Read More

Br J Oral Maxillofac Surg 2017 Nov 21;55(9):946-951. Epub 2017 Oct 21.

Department of Oral, Maxillofacial and Facial Plastic Surgery, RWTH Aachen University Hospital, Aachen, Germany.

Donor site morbidity is the most common limitation of the deep circumflex iliac artery (DCIA) flap, so the purpose of this paper is to describe a new, minimally-invasive, approach to its harvest using virtual surgical planning and CAD/CAM technology to reduce functional and aesthetic morbidity at the donor site. Virtual surgical planning was based on preoperative computed tomographic data. A newly-designed surgical guide made using CAD/CAM technology was used to transfer the virtual surgical plan to the site of operation. Read More

Microsurgery 2017 Nov 14;37(8):896-901. Epub 2017 Aug 14.

Orthopedic Department, Affiliated Zhongshan Hospital of Dalian University, No 6 Jiefang Street, Zhongshan District, Dalian, China.

Background: Osteonecrosis of the femoral head (ONFH) often affects young active adults and leads to destruction of the hip joint and disabling arthritis. Several procedures have been developed to arrest the progress of osteonecrosis and postpone the procedure of total hip replacement especially in young patients. The aim of this multicenter study was to analyze the results of the use of the vascularized iliac bone flap transfer for management of ONFH. Read More

Tissue Eng Part C Methods 2017 12 31;23(12):889-899. Epub 2017 Aug 31.

Division of Plastic Surgery, Cincinnati Children's Hospital Medical Center , Cincinnati, Ohio.

Alveolar (gumline) clefts are the most common congenital bone defect in humans, affecting 1 in 700 live births. Treatment to repair these bony defects relies on autologous, cancellous bone transfer from the iliac crest. This harvest requires a second surgical site with increased surgical time associated with potential complications, while providing only limited cancellous bone. Read More

HSS J 2017 Jul 19;13(2):178-185. Epub 2016 Sep 19.

Orthopedic Department, Al-Demerdash Hospital, Ain Shams University, Abbassia Square, Abbassia, 11381 Cairo, Egypt.

Background: Fibular hemimelia is a congenital disorder that is characterized by the absence of the fibula that could be either partial or complete. Successful management aims to restore normal weight bearing and normal limb length. The introduction of the Ilizarov method of limb lengthening has provided an attractive alternative to amputation. Read More