Search Our Scientific Publications & Authors

JBJS Essent Surg Tech 2020 Jan-Mar;10(1). Epub 2020 Mar 23.

Vienna Shoulder & Sports Clinic, Vienna, Austria.

Anterior shoulder instability is commonly associated with injuries to the labrocapsular structures of the glenohumeral joint and with osseous glenoid defects of varying degree. If the bone defect exceeds a clinically relevant threshold, mere soft-tissue repairs result in high rates of recurrent instability and the glenoid needs to be reconstructed with osseous augmentation. The most popular techniques for glenoid reconstruction include variations of coracoid transfer or bone-block procedures; however, these procedures are not free from risks and complications, which are often related to the method of fixation. Read More

Int J Spine Surg 2020 Feb 10;14(Suppl 1):3-13. Epub 2020 Feb 10.

Engineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Orthopaedics, The University of Toledo, Toledo, Ohio.

Background: The sacroiliac joints (SIJs), the largest axial joints in the body, sit in between the sacrum and pelvic bones on either side. They connect the spine to the pelvis and thus facilitate load transfer from the lumbar spine to the lower extremities. The majority of low back pain (LBP) is perceived to originate from the lumbar spine; however, another likely source of LBP that is mostly overlooked is the SIJ. Read More

Microorganisms 2019 Nov 18;7(11). Epub 2019 Nov 18.

Departamento de Anatomía Patológica del Nuevo Hospital Civil de Guadalajara, Salvador Quevedo y Zubieta 750, Independencia Oriente, Guadalajara 44340, Mexico.

Chronic infection with the intracellular parasite produces an accumulation of cysts in the brain and muscle, causing tissue damage. The cysts in the brain motor regions affect some kinematic locomotion parameters in the host. To localize the brain cysts from and study the changes in kinematic locomotion in C57BL/6 mice. Read More

J Clin Orthop Trauma 2019 Oct 14;10(Suppl 1):S231-S233. Epub 2018 Dec 14.

Department of Trauma and Emergency, AIIMS Bhubaneswar, Sijua, Patrapada, Odisha, 751019, India.

Defect in the lateral malleolus along with lateral ligamentous injury of ankle is rare. It occurs mainly due to resection of distal fibula tumors and severe trauma leading to loss of lateral malleolus. Lateral malleoli has the major contribution in weight transmission to foot and ankle stability. Read More

Arch Orthop Trauma Surg 2019 Oct 18;139(10):1417-1424. Epub 2019 Jul 18.

Department of Rheumatology and Arthroscopy, Marienkrankenhaus Düsseldorf-Kaiserswerth, An St Swidbert 17, Düsseldorf, Germany.

Aim: The subscapularis muscle is an important active stabilizer of the glenohumeral joint. For this radiological study, we investigated if its radiological integrity is affected after arthroscopic glenoid reconstruction. In the technique used, an autologous iliac crest graft is transported through the rotator interval, and the graft is fixed via an antero-inferior portal with compression screws. Read More

Arch Orthop Trauma Surg 2019 Oct 18;139(10):1435-1444. Epub 2019 Jun 18.

Department of Shoulder and Elbow Surgery, Center for Musculoskeletal Surgery (CMSC), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

Background: The coracoid transfer represents a treatment option for patients with recurrent shoulder instability. Only a few studies exist about the complication rate of the coracoid transfer as a revision surgery following failed soft tissue stabilization. The purpose of this study was to analyze the results and complication rate after coracoid transfer as a revision surgery. Read More

J Ayub Med Coll Abbottabad 2019 Apr-Jun;31(2):156-161

Department of Plastic Surgery, Shifa International Hospital, Islamabad, Pakistan.

Background: Free tissue transfer is a routine practice in adults with good success rates. Further advances in techniques and microsurgical skills have proved that free tissue transfer in paediatric population is feasible, reliable and safe.

Methods: This study is conducted to compare anastomosis duration, total general anaesthesia duration, hospital stay and outcomes of flaps (survival, partial loss, complete loss, complications) in paediatric group (age <15 years) and adult group (15-70 years age). Read More

Eur Rev Med Pharmacol Sci 2019 Apr;23(2 Suppl):12-18

Orthopedic Department, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.

Clinical management of a septic non-union of the distal humerus is challenging and is complicated by the diversity of potential treatments which are variably successful. We report a novel and very successful treatment of a 58-year-old man presenting an infected non-union of the right distal humerus, secondary to a closed fracture initially treated with two anatomic plates. After hardware removal, a two-stage reconstruction was performed. Read More

Int Orthop 2019 11 15;43(11):2601-2605. Epub 2019 Jan 15.

Paley Orthopedic and Spine Institute, St. Mary's Hospital, West Palm Beach, FL, 33407, USA.

Purpose: Stump overgrowth is the main problem of limb amputation in children. Many surgical procedures have been developed to overcome the problem, but all have shown inconsistent results. The only surgical procedure that has been successful in preventing overgrowth is capping of the amputated limb with a cartilaginous cap taken from the amputated limb, usually from the head of fibula. Read More

Cureus 2018 Oct 10;10(10):e3437. Epub 2018 Oct 10.

Otolaryngology, Aga Khan University Hospital, Karachi, PAK.

Introduction Ameloblastoma is a locally destructive tumor with a propensity for recurrence if not entirely excised. Management of ameloblastoma poses a challenge for all involved in the field of head and neck surgery because successful treatment requires not only adequate resection but also a functional and aesthetically acceptable reconstruction of the residual defect. Methods Patients who had histologically proven ameloblastoma between 1991 and 2009 were identified from the database of Aga Khan University Hospital. Read More

Spine Deform 2018 Sep - Oct;6(5):498-506

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 W. Thomas Rd., Phoenix, AZ 85013, USA. Electronic address:

Study Design: Cadaveric feasibility study and case report.

Objective: To determine if it is feasible to rotate pedicled vascularized bone graft (VBG) from L1 to S1 via a posterior approach.

Summary Of Background Data: VBG has been used to successfully augment fusion rates in various skeletal pathologies. Read More

Otolaryngol Head Neck Surg 2019 01 24;160(1):100-106. Epub 2018 Jul 24.

1 Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Objective: This study evaluated the accuracy of the Surgical Risk Calculator (SRC) of the ACS NSQIP (American College of Surgeons National Surgical Quality Improvement Program) in predicting head and neck microvascular reconstruction outcomes.

Study Design: Retrospective analysis.

Setting: Tertiary medical center. Read More

Orthop Traumatol Surg Res 2018 10 7;104(6):911-915. Epub 2018 Jun 7.

Service de chirurgie orthopédique et traumatologique, CHU de Maison-Blanche, 45, rue Cognacq-Jay, 51092 Reims cedex, France. Electronic address:

Introduction: Management of septic non-union of the tibia requires debridement and excision of all infected bone and soft tissues. Various surgical techniques have been described to fill the bone defect. The "Induced Membrane" technique, described by A. Read More

J Reconstr Microsurg 2018 Nov 12;34(9):719-728. Epub 2018 May 12.

Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Background:  The superficial circumflex iliac artery (SCIA)-based iliac bone flap has yet to be widely used. The purpose of this article is to validate the feasibility of SCIA-based iliac bone flap transfers for reconstruction of small to moderate-sized bony defects. Retrospective outcome comparisons between SCIA-based iliac bone flaps and fibula flaps were made. Read More

Aust Dent J 2018 03;63 Suppl 1:S108-S113

Royal Brisbane and Women's Hospital, University of Queensland, Herston Qld, Australia.

Prosthetic replacements in the 19th and early 20th century were superseded by pedicled flaps and obturators. These have subsequently been superseded by free tissue transfer which currently is the mainstay of reconstructive jaw surgery. Although malignant and benign processes of the jaws are the predominant cause of segmental defects, a significant proportion still occurs due to trauma, or even iatrogenic causes such as radiotherapy. Read More

Microsurgery 2018 Nov 7;38(8):882-888. Epub 2017 Dec 7.

JMS Burn and Reconstructive Center, Jackson, Mississippi.

Purpose: We present the results of a study on the anatomy of the ascending branch of the lateral circumflex femoral artery (AB-LCFA) and the use of the pedicled iliac bone flap transfer perfused by AB-LCFA combined with external fixation for the treatment of the nonunion of upper femoral shaft fractures.

Methods: The orientation, diameter, length, and distribution of the AB-LCFA from 40 lower limbs of adult cadavers were dissected and measured. From 2000 to 2012, 13 patients with nonunion of upper femoral shaft fractures underwent pedicled iliac bone flap transfer perfused by the AB-LCFA combined with external fixation. Read More

Br J Oral Maxillofac Surg 2017 Nov 21;55(9):946-951. Epub 2017 Oct 21.

Department of Oral, Maxillofacial and Facial Plastic Surgery, RWTH Aachen University Hospital, Aachen, Germany.

Donor site morbidity is the most common limitation of the deep circumflex iliac artery (DCIA) flap, so the purpose of this paper is to describe a new, minimally-invasive, approach to its harvest using virtual surgical planning and CAD/CAM technology to reduce functional and aesthetic morbidity at the donor site. Virtual surgical planning was based on preoperative computed tomographic data. A newly-designed surgical guide made using CAD/CAM technology was used to transfer the virtual surgical plan to the site of operation. Read More

Microsurgery 2017 Nov 14;37(8):896-901. Epub 2017 Aug 14.

Orthopedic Department, Affiliated Zhongshan Hospital of Dalian University, No 6 Jiefang Street, Zhongshan District, Dalian, China.

Background: Osteonecrosis of the femoral head (ONFH) often affects young active adults and leads to destruction of the hip joint and disabling arthritis. Several procedures have been developed to arrest the progress of osteonecrosis and postpone the procedure of total hip replacement especially in young patients. The aim of this multicenter study was to analyze the results of the use of the vascularized iliac bone flap transfer for management of ONFH. Read More

Tissue Eng Part C Methods 2017 12 31;23(12):889-899. Epub 2017 Aug 31.

Division of Plastic Surgery, Cincinnati Children's Hospital Medical Center , Cincinnati, Ohio.

Alveolar (gumline) clefts are the most common congenital bone defect in humans, affecting 1 in 700 live births. Treatment to repair these bony defects relies on autologous, cancellous bone transfer from the iliac crest. This harvest requires a second surgical site with increased surgical time associated with potential complications, while providing only limited cancellous bone. Read More

HSS J 2017 Jul 19;13(2):178-185. Epub 2016 Sep 19.

Orthopedic Department, Al-Demerdash Hospital, Ain Shams University, Abbassia Square, Abbassia, 11381 Cairo, Egypt.

Background: Fibular hemimelia is a congenital disorder that is characterized by the absence of the fibula that could be either partial or complete. Successful management aims to restore normal weight bearing and normal limb length. The introduction of the Ilizarov method of limb lengthening has provided an attractive alternative to amputation. Read More

Arthroscopy 2017 Sep 15;33(9):1661-1669. Epub 2017 Jun 15.

Department of Trauma and Orthopedic Surgery, Monica Hospitals, Antwerp, Belgium.

Purpose: The purpose of this cadaveric study was to compare standard and modified coracoid transfer procedures, bicortical and tricortical iliac crest autografts, and tibial plafond and glenoid allografts with respect to glenoid surface curvature restoration.

Methods: Computed tomography scans of 8 cadaveric shoulders were acquired in 9 conditions: (1) intact, (2) 25% width defect, (3) classic Latarjet, (4) modified congruent-arc Latarjet, (5) tricortical iliac crest inner table, (6) outer table, (7) bicortical iliac crest, (8) distal tibia, and (9) glenoid allograft. Outcome measures included articular surface area, width, depth, axial and coronal radius of curvature, and subchondral articular step-off, analyzed in bone and soft-tissue window. Read More

J Plast Reconstr Aesthet Surg 2017 Aug 20;70(8):1009-1016. Epub 2017 May 20.

Division of Plastic and Reconstructive Surgery, University of Florida, Gainesville, FL, USA. Electronic address:

Background: This study aimed to describe the technique and report our experience with the reconstruction of combined proximal thumb amputations at the metacarpal base level and index finger amputation at the metacarpal level with pollicization and bilateral double toe composite transfer.

Methods: The technique consists of pollicization of the remnant index ray. Then a contralateral composite medial great toe pulp and vascularized second toe proximal interphalangeal joint flap are harvested to reconstruct the metacarpophalangeal joint of the thumb. Read More

J Craniofac Surg 2017 May;28(3):659-663

Department of Plastic, Reconstructive and Aesthetic Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Reconstruction of a midfacial defect can represent a difficult challenge for the plastic surgeon. Although many midfacial deformities have traumatic or congenital origins, the vast majority of head and neck defects occur after resection of malignant head and neck neoplasms. Autogenous reconstruction is now routinely performed for larger, complex defects resulting from surgical resection or trauma. Read More

Br J Oral Maxillofac Surg 2017 Feb 5;55(2):113-126. Epub 2017 Jan 5.

Liverpool University, Regional Maxillofacial Unit, University Hospital Aintree, Liverpool L9 1AE, United Kingdom. Electronic address:

To explore the techniques for mandibular reconstruction with composite free flaps and their outcomes, we systematically reviewed reports published between 1990 and 2015. A total of 9499 mandibular defects were reconstructed with 6178 fibular, 1380 iliac crest, 1127 composite radial, 709 scapular, 63 serratus anterior and rib, 32 metatarsal, and 10 lateral arm flaps including humerus. The failure rate was higher for the iliac crest (6. Read More

J Oral Maxillofac Surg 2016 Jun 3;74(6):1285.e1-1285.e11. Epub 2016 Mar 3.

Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China. Electronic address:

Purpose: The purpose of this study was to describe a revised approach for mandibular reconstruction with vascularized iliac crest flap using virtual surgical planning and surgical navigation.

Patients And Methods: Preoperative maxillofacial and iliac non-contrast-enhanced computed tomography (CT) scans were acquired, and CT data were imported into ProPlan CMF software (Materialise, Leuven, Belgium). We performed virtual mandibulectomy and superimposed the 3-dimensional iliac image on the mandibular defect. Read More

Plast Reconstr Surg 2016 Apr;137(4):1292-305

Melbourne, Victoria, Australia From the Jack Brockhoff Reconstructive Plastic Surgery Research Unit-Taylor Laboratory, Department of Anatomy and Neuroscience, University of Melbourne.

Background: The first successful free vascularized bone flap was performed on June 1, 1974 (and reported in 1975), using the fibula. This was followed by the iliac crest based on the superficial circumflex iliac artery in 1975 and then the deep circumflex iliac artery in 1978.

Methods: A total of 384 transfers using fibula (n = 198), iliac crest (n = 180), radius (n = 4), rib (n = 1), and metatarsal (n = 1) were used between June of 1974 and June of 2014 for reconstruction of the mandible (n = 267), maxilla (n = 20), clavicle (n = 1), humerus (n = 8), radius and ulna (n = 21), carpus (n = 3), pelvis (n = 2), femur (n = 11), tibia (n = 47), and foot bones (n = 4). Read More

World J Orthop 2015 Jun 18;6(5):421-33. Epub 2015 Jun 18.

Grant H Garcia, Joseph N Liu, David M Dines, Joshua S Dines, Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY 10021, United States.

Anterior shoulder instability with bone loss can be a difficult problem to treat. It usually involves a component of either glenoid deficiency or a Hill-Sachs lesion. Recent data shows that soft tissue procedures alone are typically not adequate to provide stability to the shoulder. Read More

JBJS Essent Surg Tech 2015 May 10;5(2):e11. Epub 2015 Jun 10.

Foot Surgery and Pediatric Orthopaedics, ATOS Clinic Heidelberg, Bismarckstraße 9-15, 69115 Heidelberg, Germany.

Introduction: A successful adjusted treatment algorithm for the correction of cavovarus foot deformity requires soft-tissue balancing procedures, in particular total split posterior tibial tendon transfer (T-SPOTT), in combination with adjunctive corrective procedures depending on the degree of deformity.

Step 1 Surgical Preparation: Place the patient in a supine position and follow a standard aseptic surgical disinfection and draping protocol, allowing access to the iliac crest.

Step 2 Steindler Release Of The Plantar Aponeurosis: Use a medial approach to access and transect the plantar aponeurosis. Read More

Int J Oral Maxillofac Surg 2015 Jun 23;44(6):675-84. Epub 2015 Mar 23.

Head and Neck Oncology, Ninth People's Hospital, School of Stomatology, Shanghai Jiao Tong University School of Medicine and Shanghai Key Laboratory of Stomatology, Shanghai, China. Electronic address:

This study represents the surgical experience of 4481 microvascular free flap cases performed at the authors' institution in China, between 1979 and 2013. Four thousand four hundred and eighty-one patients underwent reconstruction with 4640 flaps: 56% radial forearm flaps, 8% iliac crest flaps, 13% fibula flaps, 10% anterolateral thigh flaps, and other flaps. In the overwhelming majority of cases, the flap transfer was required following tumour resection (97. Read More

J Biomech 2014 Nov 22;47(14):3466-74. Epub 2014 Sep 22.

Mechanical Behaviour of Materials Laboratory, School of Engineering, University of Portsmouth, UK.

Bone-cement interface has been investigated under selected loading conditions, utilising experimental techniques such as in situ mechanical testing and digital image correlation (DIC). However, the role of bone type in the overall load transfer and mechanical behaviour of the bone-cement construct is yet to be fully quantified. Moreover, microdamage accumulation at the interface and in the cement mantle has only been assessed on the exterior surfaces of the samples, where no volumetric information could be obtained. Read More

Knee Surg Sports Traumatol Arthrosc 2016 Jun 7;24(6):1884-7. Epub 2014 May 7.

Department of Orthopaedics, Aachen University Hospital, Aachen, Germany.

In severe shoulder instability, chronic glenoid bone deficiency is a challenge for arthroscopic shoulder surgeons. This paper presents a new all-arthroscopic technique of iliac crest bone graft transfer for those patients. Transportation through the rotator interval and repositioning into the glenoid defect is achieved by use of a tracking suture, while fixation of the graft is performed by biodegradable or titanium double-helix screws. Read More

Clin Oral Investig 2015 Mar 26;19(2):413-9. Epub 2014 Apr 26.

Department of Cranio-Maxillofacial Surgery, Regensburg University Medical Centre, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany,

Objectives: The reconstruction of complex facial defects should satisfy both aesthetic and functional requirements. In the midfacial area, the nasal passage should be sufficiently separated from the orbit and the oral cavity to avoid both dysphagia and articulation disorders and to allow unimpaired nasal breathing. In the case of large defects, the use of craniofacial prostheses alone is ineffective in the restoration of functional units in the majority of patients. Read More

Foot Ankle Surg 2014 Mar 7;20(1):26-9. Epub 2013 Sep 7.

Department of Paediatric Orthopaedic and Trauma Surgery, Sheffield Children's Hospital NHS Foundation Trust, Western Bank, Sheffield S10 2TH, UK. Electronic address:

Background: We report our medium term outcomes following surgery for symptomatic planovalgus malalignment in children. The technique we describe commences with lateral column lengthening and includes subsequent bony and soft tissue procedures which are carried out 'a la carte' in response to the underlying pathology and the behaviour of the foot to the lateral column lengthening.

Methods: Surgery was undertaken on twenty five symptomatic planovalgus feet in 15 patients at a mean age of 12 years and 6 months (5 years 7 months to 16 years and 3 months). Read More

Clin Anat 2014 Mar 20;27(2):234-40. Epub 2013 Aug 20.

Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, 3800, Australia.

Biomechanical models predict that recruitment of gluteus maximus (GMax) will exert a compressive force across the sacroiliac joint (SIJ), yet this muscle requires morphologic assessment. The aims of this study were to document GMax's proximal attachments and assess their capacity to generate forces including compressive force at the SIJ. In 11 embalmed cadaver limbs, attachments of GMax crossing the SIJ were dissected and their fascicle orientation, length and attachment volume documented. Read More

BMC Biotechnol 2013 Aug 8;13:65. Epub 2013 Aug 8.

Background: Common cell based strategies for the treatment of osseous defects require the isolation and expansion of autologous cells. Since this makes such approaches time-consuming and expensive, we developed a novel expedited technology creating gene activated muscle grafts. We have previously shown that large segmental bone defects in rats can be regenerated by implantation of muscle tissue fragments activated by BMP-2 gene transfer. Read More

J Oral Maxillofac Surg 2013 Dec 25;71(12):2176-88. Epub 2013 Jul 25.

Lecturer, Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan. Electronic address:

Ossifying fibromas are bone-related benign neoplasms that are characterized by well-demarcated lesions composed of fibrocellular tissue and mineralized material with varying appearances. Although small lesions are asymptomatic, they may cause enlargement of the affected jaw and rarely require reconstructive or restorative treatments for aesthetic and functional problems. In this study, we report a 35-year-old woman who underwent multidisciplinary treatment for a large ossifying fibroma of the mandible. Read More

Foot Ankle Int 2013 Oct 26;34(10):1395-402. Epub 2013 Jun 26.

University of Texas Southwestern, Dallas, TX, USA.

Background: Avascular necrosis (AVN) or persistent nonunion occurs in situations of poor vascular supply. Some specific situations that plague the foot and ankle surgeon are talus nonunion, talus AVN, navicular AVN, and failed ankle arthrodesis with bone loss. The medial femoral condyle (MFC) flap has emerged as a popular source of vascularized corticocancelous bone. Read More

Oral Maxillofac Surg Clin North Am 2013 May;25(2):241-9

Department of Oral and Maxillofacial Surgery, College of Medicine, University of Florida, Jacksonville, FL 32209, USA.

Acquired defects of the mandible resulting from trauma, infection, osteoradionecrosis, and ablative surgery of the oral cavity and lower face are particularly debilitating. Familiarity with mandibular and cervical anatomy is crucial in achieving mandibular reconstruction. The surgeon must evaluate which components of the hard and soft tissue are missing in selecting a method of reconstruction. Read More

J Plast Reconstr Aesthet Surg 2013 Nov 19;66(11):1596-9. Epub 2013 Apr 19.

Department of Plastic and Reconstructive Surgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address:

We describe a novel free vascularised iliac bone flap based on superficial circumflex iliac perforators (SCIPs). Compared with a conventional iliac bone flap, which is based on deep circumflex iliac vessels, this flap is less invasive, less bulky and can include a reliable skin island. In addition, an SCIP-deep inferior epigastric perforator (DIEP) bipedicle soft--tissue flap has been developed, which can contribute to safer transfer of larger DIEP flaps. Read More

J Craniomaxillofac Surg 2014 Jan 7;42(1):28-34. Epub 2013 Mar 7.

Cranio-Maxillofacial and Plastic Facial Surgery, (Head: Sader, Robert MD, DMD, PhD, FEBOMFS), J. W. Goethe-University of Frankfurt Medical Center, Frankfurt, Germany.

Severely deformed or absent temporomandibular joints (TMJ) benefit from total alloplastic joint replacement and large mandibular defects from revascularized free tissue transfer for reconstruction. However no cases of their combined one-stage placement with outcomes can be found in the literature. We present two cases with different indications and reconstruction. Read More

J Hand Surg Am 2013 May 27;38(5):935-940.e1. Epub 2013 Feb 27.

Department of Orthopedics, University of British Columbia, Vancouver, British Columbia, Canada.

Purpose: Wrist arthrodesis after resection of a giant cell tumor of the distal radius can be performed using a vascularized free fibular transfer (VFFT) or a nonvascularized structural iliac crest transfer (NICT). The purpose of this study was to compare the union times, functional outcomes, and complications after these procedures.

Methods: We identified 27 patients at 2 centers: 14 underwent VFFT, and 13 NICT. Read More

Am J Sports Med 2013 Mar 7;41(3):519-27. Epub 2013 Feb 7.

Orthopaedic Department, University of Basel Hospital, Basel, Switzerland.

Background: Osteochondral lesions (OCLs) of the talus are a common entity in sports orthopaedics. There are several operative techniques with a good outcome on follow-up examinations. However, limitations such as sacrificing healthy cartilage (osteochondral autograft transfer system [OATS], mosaicplasty), multiple-stage operative procedures (matrix-induced autologous chondrocyte transplantation [MACI], autologous chondrocyte implantation [ACI]), high costs (ACI, allograft), and limited availability (allograft) do remain and reflect potential drawbacks of the currently used techniques. Read More

Plast Reconstr Surg 2013 Feb;131(2):310-22

Plastic Surgery and Reconstructive Microsurgery, Hospital Quirón, Madrid, Spain.

Background: There are few references to the reconstructive possibilities of the ascending branch of the lateral circumflex femoral artery other than the tensor fasciae latae muscle flap and the so-called muscle pedicle bone grafting technique.

Methods: An anatomical study was performed to evaluate the ascending branch of the lateral circumflex femoral artery and its contribution, through direct branches, to the iliac crest and skin.

Results: In nine of 20 dissections, a small branch of the ascending branch of the lateral circumflex femoral artery was found to reach the iliac crest in the space defined by the rectus femoris, gluteal muscles, and tensor fasciae latae. Read More

J Cell Biochem 2013 Jan;114(1):134-43

Department of Comparative Biomedical Science, University of Teramo, 64100 Teramo, Italy.

Mesenchymal stem cells (MSCs) are an important cell population in the bone marrow microenvironment. MSCs have the capacity to differentiate in vitro into several mesenchymal tissues including bone, cartilage, fat, tendon, muscle, and marrow stroma. This study was designed to isolate, expand, and characterize the differentiation ability of sheep bone marrow-derived MSCs and to demonstrate the possibility to permanently express a reporter gene. Read More

Man Ther 2012 Dec 22;17(6):531-7. Epub 2012 Jun 22.

Research Institute MOVE, Faculty of Human Movement Sciences, VU University Amsterdam, Amsterdam, The Netherlands.

The Active Straight Leg Raise (ASLR) is an important test in diagnosing pelvic girdle pain (PGP). It is difficult to understand what happens normally during the ASLR, let alone why it would be impaired in PGP. In the present study, healthy subjects performed the ASLR under normal conditions, with weight added above the ankle, and while wearing a pelvic belt. Read More

J Anat 2012 Dec 15;221(6):568-76. Epub 2012 May 15.

Department of Anatomy, University of New England College of Osteopathic Medicine, Biddeford, ME 04005, USA.

Movement and stability of the lumbosacral region is contingent on the balance of forces distributed through the myofascial planes associated with the thoracolumbar fascia (TLF). This structure is located at the common intersection of several extremity muscles (e.g. Read More

Plast Reconstr Surg 2011 Apr;127(4):1553-60

Case Western Reserve Medical School and MetroHealth Medical Center, Cleveland, Ohio 44109, USA.

Background: The iliacus muscle is proposed as a new solution for coverage of small to medium defects where either a bulky flap or conspicuous donor sites are undesirable.

Methods: Dissection and Microfil studies were performed on fresh cadavers to define the gross and microvascular anatomy of the muscle. Live evaluation of the muscle was performed in combination with multiple iliac crest free tissue transfer procedures. Read More

Plast Reconstr Surg 2010 Sep;126(3):964-72

Clínica Cavadas, Valencia, Spain.

Background: Massive bone loss of the elbow in young patients is a complex injury. A series of five cases of massive loss of the elbow joint reconstructed with single or double vascularized bone transfers is reported.

Methods: Five patients with nonacute massive bone loss of the distal humerus (two cases) or distal humerus and proximal ulna (three cases) were reconstructed with a single (two cases) or double (three cases) microvascular vascularized bone transfer from the iliac crest, the fibula, or the scapula. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 Jan 29;111(1):51-7. Epub 2010 Jun 29.

Department of Oral and Maxillofacial Surgery, Technische Universität München, Klinikum Rechts der Isar, München, Germany.

Objective: Loss of all or part of the maxilla as a result of tumor ablation has both functional and aesthetic consequences. Reconstruction of the maxilla remains a challenge despite the availability of several flaps and the skills of the prosthodontist. We have analyzed a series of maxillary resections that underwent flap reconstruction to guide planning of the rehabilitation of patients with such defects. Read More

Cytotherapy 2010 Sep;12(5):593-604

Department of Surgery, Clinical Research Center, Oulu University Hospital, Oulu, Finland.

Background Aims: Congenital pseudarthrosis of the tibia (CPT) caused by neurofibromatosis type 1 (NF1) is a refractory disease occurring in childhood. We present two cases that had failed all earlier treatment attempts and, as a last treatment attempt, the patients were chosen to receive mesenchymal stromal cell (MSC) transplantation prior to amputation.

Methods: The MSC from bone marrow (BM) were harvested from the iliac crest and cultured in osteoinductive medium for 3 weeks. Read More