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    Itraconazole-induced thrombocytopenia.
    Cutan Ocul Toxicol 2016 Dec 21:1-2. Epub 2016 Dec 21.
    a Bahcesehir University, Faculty of Medicine, Department of Dermatology , Istanbul , Turkey , and.
    Itraconazole is one of the systemic treatment options for extensive tinea versicolor. A male patient who developed thrombocytopenia during the treatment of tinea versicolor by itraconazole is reported in this manuscript. He was diagnosed to develop thrombocytopenia on the third day of treatment. Read More

    A clinical study of cutaneous changes in pregnancy.
    J Epidemiol Glob Health 2017 Mar 19;7(1):63-70. Epub 2016 Nov 19.
    Department of Dermatology, Government Medical College, Alappuzha, Kerala, India.
    Background/objective: Pregnant women experience a myriad of physiological and metabolic changes that affect different organ systems in the body. Cutaneous and appendageal alterations that manifest during pregnancy are largely modulated by hormonal, immunologic, and metabolic factors. Detailed reports encompassing physiological changes and specific dermatoses of pregnancy and effects of various dermatoses on pregnant women are scanty in literature. Read More

    A survey of herbal weeds for treating skin disorders from Southern Thailand: Songkhla and Krabi Province.
    J Ethnopharmacol 2016 Dec 28;193:574-585. Epub 2016 Sep 28.
    Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
    Ethnopharmacological Relevance: Skin diseases are common health problems which affecting to all ages. In Thailand, the number of patients diagnosed with skin diseases is increasing every year. Nowadays, The Ministry of Public Health is supporting and promoting herbs for treating various disorders, including disorders of the skin to reduce the problem of antibiotic resistance and adverse drug reactions. Read More

    Dermoscopy in General Dermatology: A Practical Overview.
    Dermatol Ther (Heidelb) 2016 Dec 9;6(4):471-507. Epub 2016 Sep 9.
    Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.
    Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. Read More

    Comparative clinical trial: fluconazole alone or associated with topical ketoconazole in the treatment of pityriasis versicolor.
    Tunis Med 2016 Feb;94(2):107-11
    Background: The efficacy of ketoconazole and fluconazole in pityriasis versicolor had been proved.

    Aim: To compare the efficacy and the safety of two doses of fluconazole given 1 week apart alone or associated to ketoconazole shampoo.

    Methods: Our study included all patients with pityriasis versicolor who attended in dermatology department of Habib Thameur Hospital, Tunis (over a 21-month period). Read More

    Oral Antifungal Drugs in the Treatment of Dermatomycosis.
    Med Mycol J 2016 ;57(2):J71-5
    Department of Dermatology, Tokyo Women's Medical University.
    Oral antifungal drugs are used primarily to treat tinea unguium; however, they are also useful for other types of tinea. For example, a combination of topical and oral antifungal drugs is effective in hyperkeratotic tinea pedis that is unresponsive to topical monotherapy. In cases of tinea facialis adjacent to the eyes, ears, or mouth, or widespread tinea corporis, or tinea cruris involving the complex skin folds of the external genitalia, it is difficult to apply topical drugs to all the lesions; therefore, oral antifungal drugs are necessary. Read More

    Confluent and Reticulated Papillomatosis of Gougerot-Carteaud on Black Skin: Two Observations.
    Case Rep Dermatol Med 2016 5;2016:2507542. Epub 2016 Apr 5.
    Department of Dermatology and Venerology, Teaching Hospital of Treichville, BP 3, Abidjan, Côte d'Ivoire.
    Confluent and reticulated papillomatosis of Goujerot-Carteaud is a rare and benign skin disease characterized by flat papules taking a reticulated appearance. It is a skin disease of unknown etiology and nosology that is always discussed. This disease preferentially involves the chest and interscapular regions. Read More

    Mycological Considerations in the Topical Treatment of Superficial Fungal Infections.
    J Drugs Dermatol 2016 Feb;15(2 Suppl):s49-55
    Trichophyton rubrum remains the most common pathogenic dermatophyte in the United States, Europe, and industrialized Asia, although other species are predminant elsewhere. Candida albicans is the most common pathogenic yeast, with other species occasionally encountered. Just a few of the 14 described species of Malassezia cause pityriasis versicolor worldwide. Read More

    Dermatological Complaints of the Elderly Attending a Dermatology Outpatient Clinic in Turkey: A Prospective Study over a One-year Period.
    Acta Dermatovenerol Croat 2015 ;23(4):277-81
    Assoc. Prof. Muhterem Polat, MD, Gazi University School of Medicine, Department of Dermatology, Ankara, Turkey;
    The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Read More

    Malassezia species in healthy skin and in dermatological conditions.
    Int J Dermatol 2016 May 29;55(5):494-504. Epub 2015 Dec 29.
    Institute of Pathology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
    The genus Malassezia comprises lipophilic species, the natural habitat of which is the skin of humans and other warm-blooded animals. However, these species have been associated with a diversity of dermatological disorders and even systemic infections. Pityriasis versicolor is the only cutaneous disease etiologically connected to Malassezia yeasts. Read More

    [2011 Epidemiological Survey of Dermatomycoses in Japan].
    Med Mycol J 2015 ;56(4):J129-35
    Epidemiological Investigation Committee for Human Mycoses in the Japanese Society for Medical Mycology, Chairman and Reporter.
    An epidemiological survey of dermatomycoses and their causative fungus flora in Japan for 2011 was conducted in accordance with methods and criteria of the past four surveys. The survey covered a total number of 36,052 outpatients who visited 12 dermatological clinics throughout Japan. The results were as follows. Read More

    Superficial Fungal Infections.
    Prim Care 2015 Dec;42(4):501-16
    Division of Primary Care, Family Medicine, Mayo Clinic Health System, 1921 Alice Street, Waycross, GA 31501, USA.
    Superficial fungal infections grow in dark and moist areas and invade various parts of the body. These infections are easily treatable in immunocompetent individuals. In immunosuppressed individuals, the presentation can be quite severe, requiring use of more potent antifungal agents. Read More

    The effects of the El Niño Southern Oscillation on skin and skin-related diseases: a message from the International Society of Dermatology Climate Change Task Force.
    Int J Dermatol 2015 Dec 15;54(12):1343-51. Epub 2015 Oct 15.
    Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.
    The El Niño Southern Oscillation (ENSO) is a complex climate phenomenon occurring in the Pacific Ocean at intervals of 2-7 years. The term refers to fluctuations in ocean temperatures in the tropical eastern Pacific Ocean (El Niño [the warm phase of ENSO] and La Niña [the cool phase of ENSO]) and in atmospheric pressure across the Pacific basin (Southern Oscillation). This weather pattern is attributed with causing climate change in certain parts of the world and is associated with disease outbreaks. Read More

    SIXTEEN YEARS OF PITYRIASIS VERSICOLOR IN METROPOLITAN AREA OF PORTO ALEGRE, SOUTHERN BRAZIL.
    Rev Inst Med Trop Sao Paulo 2015 Jul-Aug;57(4):277-80
    Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BR.
    Pityriasis versicolor is the most common of the diseases caused by Malassezia yeasts. The aim of this study is to determine the prevalence of pityriasis versicolor and its etiological aspects in the metropolitan area of Porto Alegre, Brazil. A retrospective cross-sectional study with data from patients of a reference hospital from 1996 to 2011 was performed. Read More

    A randomized double-blind, non-inferiority Phase II trial, comparing dapaconazole tosylate 2% cream with ketoconazole 2% cream in the treatment of Pityriasis versicolor.
    Expert Opin Investig Drugs 2015 30;24(11):1399-407. Epub 2015 Sep 30.
    a 1 State University of Campinas (UNICAMP), Faculty of Medical Sciences, Department of Pharmacology , Campinas, SP, Brazil.
    Objectives: The objective of this research was to evaluate the efficacy of a new antifungal imidazole, dapaconazole tosylate, in the treatment of Pityriasis versicolor (PV).

    Design And Methods: Sixty patients with clinical and mycological diagnosis of PV were randomly assigned to receive either 1 g dapaconazole tosylate 2% cream or 1 g ketoconazole 2% cream. Treatments were applied once a day for 28 days. Read More

    Dermatophytes and other associated fungi in patients attending to some hospitals in Egypt.
    Braz J Microbiol 2015 Jul-Sep;46(3):799-805. Epub 2015 Jul 1.
    Dermatology Department, Faculty of Medicine, Cairo University, Giza, Egypt .
    Dermatophytes are keratinophilic fungi that infect keratinized tissues causing diseases known as dermatophytoses. Dermatophytes are classified in three genera, Epidermophyton, Microsporum, and Trichophyton. This investigation was performed to study the prevalence of dermatomycosis among 640 patients being evaluated at the dermatology clinics at Kasr elainy, El-Husein and Said Galal hospitals in Cairo and Giza between January 2005 and December 2006. Read More

    Malassezia Pneumonia: A Rare Complication of Parenteral Nutrition Therapy.
    JPEN J Parenter Enteral Nutr 2016 Nov 6;40(8):1194-1196. Epub 2015 Jul 6.
    Indiana University School of Medicine, Indianapolis, Indiana.
    Malassezia species (formerly known as Pityrosporum) are part of normal human skin flora and have been associated with benign dermatologic conditions, such as seborrheic dermatitis and tinea versicolor. In rare cases, however, Malassezia has been associated with systemic disease in immunocompromised patients and infants in the neonatal intensive care unit. Malassezia species require long-chain fatty acids for growth and therefore have a known predilection for individuals receiving lipid containing intravenous parenteral nutrition (PN). Read More

    Could nanovesicles containing a penetration enhancer clinically improve the therapeutic outcome in skin fungal diseases?
    Nanomedicine (Lond) 2015 2;10(13):2017-31. Epub 2015 Jul 2.
    Department of Pharmaceutics, Faculty of Pharmacy, October 6 University, Giza Governorate, Egypt.
    Aim: To study whether the formulation of an antifungal drug in nanovesicular form containing skin penetration enhancer would clinically modulate its therapeutic effectiveness.

    Materials & Methods: Nanovesicles containing different skin penetration enhancers 'PEVs' were prepared and loaded with sertaconazole. Penetration-enhancer vesicles were characterized for entrapment efficiency, particle size, zeta potential, elasticity, viscosity, morphology and ex vivo skin deposition. Read More

    Burden of serious fungal infections in the Dominican Republic.
    J Infect Public Health 2016 Jan-Feb;9(1):7-12. Epub 2015 May 28.
    The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; The University Hospital of South Manchester, National Aspergillosis Centre (NAC), Manchester, UK.
    The Dominican Republic (DR) is the second largest Caribbean nation and, with Haiti, the DR accounts for nearly three-quarters of the cases of human immunodeficiency virus (HIV) infection in the Caribbean region and the highest rates of TB in the Americas. The present study estimated the burden of serious fungal infections and some other mycoses in the DR. The data were extracted from the World Health Organization Stop Tuberculosis (WHO STOP TB) program, the Joint United Nations Program on HIV/AIDS (UNAIDS), and searches for relevant literature via MEDLINE, PubMed, MedFacts, and so on. Read More

    [Cutaneous Malassezia infections and Malassezia associated dermatoses: An update].
    Hautarzt 2015 Jun;66(6):465-84; quiz 485-6
    Labor für medizinische Mikrobiologie, Partnerschaft Prof. Dr. med. Pietro Nenoff & Dr. med. Constanze Krüger, Straße des Friedens 8, 04579, Mölbis, Deutschland,
    The lipophilic yeast fungus Malassezia (M.) spp. is the only fungal genus or species which is part of the physiological human microbiome. Read More

    Mycology - an update Part 3: Dermatomycoses: topical and systemic therapy.
    J Dtsch Dermatol Ges 2015 May;13(5):387-410; quiz 411
    Medical Microbiology Laboratory, Mölbis, Germany.
    Treatment of dermatophyte infections is based on the clinical picture and mycological detection of the causative pathogen. Based on the appropriate indication, onychomycosis can be treated topically using an antimycotic nail lacquer. Atraumatic nail abrasion with 40 % urea ointment has a beneficial effect on healing. Read More

    The Rise and Fall of Oral Ketoconazole.
    J Cutan Med Surg 2015 Jul-Aug;19(4):352-7. Epub 2015 Mar 5.
    Mediprobe Research Inc., London, Ontario, Canada.
    Background: Ketoconazole was the first broad-spectrum oral antifungal agent available to treat systemic and superficial mycoses. Evidence of hepatotoxicity associated with its use emerged within the first few years of its approval. Growing evidence of serious side effects including endocrine dysregulation, several drug interactions, and death led to the review of oral ketoconazole in 2011. Read More

    Malassezia species and their associated skin diseases.
    J Dermatol 2015 Mar;42(3):250-7
    Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
    Malassezia spp. are lipophilic fungi that occur on all skin surfaces of humans and animals as commensal and pathogenic organisms. In the 2000s, several new species were added to the Malassezia genus by Japanese researchers. Read More

    The spectrum of Malassezia species isolated from students with pityriasis vesicolor in Nigeria.
    Mycoses 2015 Apr 20;58(4):203-8. Epub 2015 Feb 20.
    Dermatology unit, Department of Internal Medicine, University of Abuja Teaching Hospital, Gwagwalada, Nigeria; Center for International Health, Ludwig Maximilian University, Munich, Germany.
    Pityriasis versicolor (PV) is a common superficial fungal infection of the skin caused by Malassezia. Initially M. furfur was suggested as its main aetiological agent; however, more recent studies suggest M. Read More

    Perpetually perplexing pediatric patients: it's complicated: part 2.
    Pediatr Ann 2015 Jan;44(1):12-7
    Many pediatric patients that you encounter will challenge your diagnostic and therapeutic skills. As the following cases will illustrate, some will perplex you with their esoteric or convoluted illnesses despite your best attempts. Although their initial presentation may often be mundane, thorough history taking and physical examination, and a keen "clinical intuition" will be invaluable. Read More

    The Prevalence and Pattern of Superficial Fungal Infections among School Children in Ile-Ife, South-Western Nigeria.
    Dermatol Res Pract 2014 10;2014:842917. Epub 2014 Dec 10.
    Department of Dermatology & Venereology, Obafemi Awolowo University, Ile-Ife, Nigeria.
    Fungal infections of the skin and nails are common global problems with attendant morbidity among affected individuals. Children are mostly affected due to predisposing factors such as overcrowding and low socioeconomic factors. The aim of this study was to determine the prevalence and the clinical patterns of superficial fungal infections among primary school children in Ile-Ife. Read More

    Cutaneous fungal infection in a renal transplantation patient due to a rare fungus belonging to order Pleosporales.
    Indian J Med Microbiol 2015 Jan-Mar;33(1):165-7
    Department of Microbiology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
    Fungal infections are being increasingly reported from immuno-compromised as well as immuno-competent patients. Transplant patients are on long term immunosuppressive therapy which makes them highly vulnerable to opportunistic fungal infections .These infections can be cutaneous or systemic. Read More

    [Superficial mycoses in patients from Anzoátegui state, Venezuela, period 2002-2012].
    Invest Clin 2014 Dec;55(4):311-20
    Universidad de Oriente, Barcelona, Venezuela.
    Superficial fungal diseases that affect the skin and its appendages are frequently seen in basic triage and in dermatology services. These diseases are distributed in Venezuela with an incidence of 92.9%. Read More

    Molecular identification and prevalence of malassezia species in pityriasis versicolor patients from kashan, iran.
    Jundishapur J Microbiol 2014 Aug 1;7(8):e11561. Epub 2014 Aug 1.
    Medical Parasitology and Mycology Department, Kashan University of Medical Sciences, Kashan, IR Iran.
    Background: Malassezia species are lipophilic yeasts found on the skin surface of humans and other warm-blooded vertebrates. It is associated with various human diseases, especially pityriasis versicolor, which is a chronic superficial skin disorder.

    Objectives: The aim of the present study was to identify Malassezia species isolated from patients' samples affected by pityriasis versicolor, using molecular methods in Kashan, Iran. Read More

    An analysis of the Malassezia species distribution in the skin of patients with pityriasis versicolor in Chengdu, China.
    ScientificWorldJournal 2014 10;2014:182596. Epub 2014 Aug 10.
    Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China.
    Pityriasis versicolor (PV) is a common clinical problem associated with Malassezia species (Malassezia spp.). Controversies remain regarding the specific species involved in the development of PV. Read More

    Mycology - an update part 2: dermatomycoses: clinical picture and diagnostics.
    J Dtsch Dermatol Ges 2014 Sep;12(9):749-77
    Laboratory for Medical Microbiology, Mölbis, Germany.
    Most fungal infections of the skin are caused by dermatophytes, both in Germany and globally. Tinea pedis is the most frequent fungal infection in Western industrial countries. Tinea pedis frequently leads to tinea unguium, while in the elderly, both may then spread causing tinea corporis. Read More

    Uncommon presentations of tinea versicolor.
    Dermatol Pract Concept 2014 Jul 31;4(3):93-6. Epub 2014 Jul 31.
    Tufts Medical Center, Department of Dermatology, Boston, MA, USA.
    Tinea versicolor (TV) is a common cutaneous fungal infection characterized by superficial scaling and a mild disturbance of skin pigmentation. It typically affects the chest, upper back, and shoulders. However, involvement of more unusual regions of the body such as the face and scalp, arms and legs, intertriginous sites, genitalia, areolae, and palms and soles has been reported. Read More

    Prevalence of skin diseases in civilian and military population in a Turkish military hospital in the central Black Sea region.
    J R Army Med Corps 2015 Jun 4;161(2):112-5. Epub 2014 Aug 4.
    Merzifon Military Hospital, Clinic of Internal Medicine, Amasya, Turkey.
    Objectives: There are no epidemiological studies comparing the prevalence of skin diseases between civilian and military populations. We sought to determine and compare the prevalence of skin conditions between civilian and military populations.

    Methods: A total of 3382 male patients (1148 military and 2234 civilian) were retrospectively and consecutively evaluated at Merzifon Military Hospital in the central Black Sea Region of Turkey. Read More

    Fungi on the skin: dermatophytes and Malassezia.
    Cold Spring Harb Perspect Med 2014 Aug 1;4(8). Epub 2014 Aug 1.
    Procter & Gamble Company, Mason, Ohio 45040.
    Several human skin diseases and disorders are associated with two groups of fungi, the dermatophytes and Malassezia. Although these skin-related problems are not generally life threatening, they are among the most common diseases and disorders of mankind. These fungi are phylogenetically divergent, with the dermatophytes within the Ascomycota and Malassezia within Basidiomycota. Read More

    Can pityriasis versicolor be treated with 2% ketoconazole foam?
    J Drugs Dermatol 2014 Jul;13(7):855-9
    Background: Pityriasis (tinea) versicolor is a superficial fungal infection of the stratum corneum caused by Malassezia species. The diagnosis is made clinically by its classic appearance of round or oval macules with fine scale that may be hyperpigmented or hypopigmented. Diagnosis may also be confirmed with microscopic evaluation of skin scrapings that reveal both short, stubby hyphae, and spores under KOH preparation. Read More

    Pityriasis versicolor: an update on pharmacological treatment options.
    Expert Opin Pharmacother 2014 Aug 3;15(12):1707-13. Epub 2014 Jul 3.
    University of Toronto, Department of Medicine , Toronto , Canada.
    Introduction: Pityriasis versicolor (PV) is a superficial fungal infection caused by Malassezia species; a yeast that naturally colonizes on the skins surface. High efficacy rates are generally obtained with both topical and systemic treatments. However, recurrence rates following successful treatment remain high and there are no dosage guidelines available for administration of systemic antifungal agents that carry risks of adverse events. Read More

    Dermatologic conditions in teenage adolescents in Nigeria.
    Adolesc Health Med Ther 2014 27;5:79-87. Epub 2014 May 27.
    Department of Pediatrics, University of Calabar, Calabar, Cross River State, Nigeria.
    Background: Skin disorders are common in adolescents, and the impact on quality of life can be enormous, particularly when viewed against the backdrop of the visibility of skin diseases and the psychologically vulnerable period of adolescence. However, few studies have documented the magnitude of skin disorders in this subset of individuals. We therefore estimated the point prevalence and pattern of dermatologic conditions in adolescents attending various secondary schools in Calabar, Southern Nigeria. Read More

    Infective skin conditions in an adult sea-going population.
    J R Nav Med Serv 2014 ;100(1):47-55
    Infective skin conditions represent a significant element of the caseload for sea-going and shore-side clinicians. They are common within the wider military setting due to the frequent requirement to live in close proximity to others in conditions which favour the spread of skin and soft tissue infections (SSTI). Within the UK civilian population, 24% of individuals see their family doctor for skin conditions each year, accounting for 13 million primary care consultations annually. Read More

    Fungemia and interstitial lung compromise caused by Malassezia sympodialis in a pediatric patient.
    Rev Iberoam Micol 2015 Apr-Jun;32(2):118-21. Epub 2014 May 24.
    Instituto de Medicina Regional, Facultad de Medicina, Universidad Nacional del Nordeste, Resistencia, Argentina. Electronic address:
    A case of fungemia with interstitial lung compromise caused by Malassezia sympodialis is reported in an obese pediatric patient on long-term treatment with inhaled corticosteroids for asthma. The patient was hospitalized due to a post-surgical complication of appendicitis. The patient was treated with amphotericin B for 3 weeks, with good clinical evolution and subsequent negative cultures. Read More

    [Trichophyton rubrum onychomycosis with secondary Aspergillus versicolor infection in a 12-year-old girl: successful topical therapy with terbinafine-urea ointment].
    Hautarzt 2014 Jul;65(7):628-32
    Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gaffkystr. 14, 35385, Gießen, Deutschland,
    Case Report: A 12-year-old with a functional circulatory disturbance had toe nail onychomycosis caused by Trichophyton rubrum. There were no other underlying diseases.

    Therapy And Outcome: Oral therapy with terbinafine 125 mg once weekly in addition to ciclopirox nail lacquer was ineffective. Read More

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