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    Management of mycoses in daily practice.
    G Ital Dermatol Venereol 2017 Dec;152(6):642-650
    Department of Pathophysiology and Transplantation, Università degli Studi di Milano, IRCCS Foundation, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy -
    The guideline recommendations, albeit founded on thorough reviews of clinically relevant literature data, are often not immediately adaptable to everyday life. Considering the marked heterogeneity of superficial mycoses, each of them requires specific management in a real life context; in all cases diagnostic confirmation is required with microscopic and culture examination. In tinea capitis oral therapy is necessary (minimum six weeks) and should be continued until clinical and, above all, mycological healing. Read More

    Molecular and Phenotypic Identification and Speciation of Malassezia Yeasts Isolated from Egyptian Patients with Pityriasis Versicolor.
    J Clin Diagn Res 2017 Aug 1;11(8):DC12-DC17. Epub 2017 Aug 1.
    Lecturer, Department of Dermatology, Andrology and Sexually Transmitted Diseases, Faculty of Medicine, Mansoura University, Mansoura, El-Dakhelia, Egypt.
    Introduction: Pityriasis Versicolor (PV) is a common health problem caused by genus Malassezia, a lipophilic fungi found as a part of the normal flora of skin. Although PV is common in Egypt, there is little information regarding the Malassezia species distribution in PV patients to date.

    Aim: To spot a light on the distribution and clinico-epidemiological features of the Malassezia species in PV patients and healthy individuals that were established by conventional phenotypic and molecular techniques. Read More

    Epidemiology of dermatomycoses in Kerman province, southeast of Iran: A 10-years retrospective study (2004-2014).
    Microb Pathog 2017 Sep 27;110:561-567. Epub 2017 Jul 27.
    School of Medicine, Bam University of Medical Sciences, Bam, Iran.
    Objectives: Superficial and cutaneous fungal infections (SCFIs) are an important public health problem and are common in tropical and subtropical countries. Pityriasis versicolor, dermatophytosis, erythrasma, onychomycosis, and otomycosis are the major diseases associated with SCFIs. The aim of this study was to evaluate the prevalence and causative agents of dermatomycoses over a period of 10 years in Kerman province, southeast of Iran. Read More

    Acquired epidermodysplasia verruciformis occurring in a renal transplant recipient.
    Cutis 2017 May;99(5):E9-E12
    Department of Dermatology, Geisinger Medical Center, Danville, Pennsylvania, USA.
    Acquired epidermodysplasia verruciformis (EDV) is a rare condition occurring in patients with depressed cellular immunity, particularly individuals with human immunodeficiency virus (HIV). Acquired EDV is less commonly reported in recipients of stem cell or solid organ transplantation. This condition typically manifests within 5 years of initial immunosuppression and can present as multiple hypopigmented to red, tinea versicolor-like macules or as multiple verrucous, flat-topped papules distributed over the trunk, arms, and legs. Read More

    [Pityriasis versicolor in infants: unusual clinical presentation and role of corticosteroids used as depigmenting agent for cosmetic purposes in the mother].
    Pan Afr Med J 2017 23;26:31. Epub 2017 Jan 23.
    UFR des Sciences de la Santé, Université de Thiès, Sénégal.
    We report two cases of Pityriasis versicolor (PV) in infants aged 12 and 18 months. The latter were brought to medical attention because of hypochromic and achromic, round macules involving the limbs and the face. Physical examination of their mothers showed voluntary depigmentation for cosmetic purposes due to the use of corticosteroids and hydroquinone, on average, over a 5-year period. Read More

    Folliculocentric tinea versicolor.
    Dermatol Online J 2017 02 15;23(2). Epub 2017 Feb 15.
    Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock.
    Tinea versicolor (TV) is typically an asymptomatic fungal infection of the stratum corneum owing to Malassezia overgrowth. It presents as hypo or hyperpigmented macules with fine scale that coalesce into patches on the trunk, neck, and/or arms. Presented in this report is a 34-year-old man with an interesting case of folliculocentric tinea versicolor manifesting as perifollicular hypopigmented macules on the lower back. Read More

    Presentations, Signs of Activity, and Differential Diagnosis of Vitiligo.
    Dermatol Clin 2017 Apr;35(2):135-144
    Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9069, USA. Electronic address:
    Vitiligo has a variety of presentations, including focal, acrofacial, segmental, and generalized forms. Thorough knowledge of these presentations is important to make the correct diagnosis. Signs of activity are important to recognize so that treatment is optimized. Read More

    Confluent and Reticulated Papillomatosis With Linear Pseudo-striae: A Description of 20 Cases.
    Actas Dermosifiliogr 2017 Mar 2. Epub 2017 Mar 2.
    E.S.E Centro Dermatológico Federico Lleras Acosta, Bogotá D.C., Colombia; Fundación Universitaria Sanitas, Bogotá D.C., Colombia.
    Confluent and reticulated papillomatosis, also known as Gougerot-Carteaud Syndrome, is a rare chronic disease typically affecting young adults. Of unknown etiology, the condition is characterised by oval grayish-brown or erythematous papules that coalesce to form a reticular pattern, usually on the trunk, especially in the intermammary or interscapular region and on the neck. Diagnosis is primarily clinical, based on the appearance of the lesions, the areas affected, and the response to treatment with minocycline. Read More

    Marine and Other Aquatic Dermatoses.
    Indian J Dermatol 2017 Jan-Feb;62(1):66-78
    Diving School, Naval Base, Kochi, Kerala, India.
    Occupational and recreational aquatic activity predisposes our population to a wide variety of dermatoses. Sunburn, urticaria, jellyfish stings, and contact dermatitis to rubber equipment are common allergies that are encountered in the aquatic environment. Among the infections, tinea versicolor, intertrigo, and verruca vulgaris are widespread. Read More

    Distribution of Malassezia Species in Patients with Different Dermatological Disorders and Healthy Individuals.
    Acta Dermatovenerol Croat 2016 Dec;24(4):274-281
    Professor Asja Prohić, MD, PhD, Department of Dermatovenerology, University Clinical Center of Sarajevo, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina;
    There are differences with respect to the commonly isolated Malassezia species, not only between healthy individuals and the patients with various skin diseases, but also between different countries. We investigated the species composition of Malassezia microflora on the skin of patients with Malassezia-associated diseases and of healthy subjects (HS). Two hundred and fifty skin scrapings from patients with pityriasis versicolor (PV), seborrheic dermatitis (SD), atopic dermatitis (AD), psoriasis (PS), and healthy subjects (HS), fifty each, were inoculated into Sabouraud dextrose agar and into modified Dixon agar and identified using conventional culture-based methods. Read More

    Atrophic pityriasis versicolor occurring in a patient with Sjögren's syndrome.
    BMJ Case Rep 2017 Jan 18;2017. Epub 2017 Jan 18.
    Unit of Dermatology, University of Padua, Padua, Italy.
    Pityriasis versicolor is one of the most frequent epidermal mycotic infections in the world, but its atrophic variant is rarely described. The aetiology of the atrophy is still unknown, and two main hypotheses have been formulated, one suggesting a correlation with long-term use of topical steroids and the other a delayed type hypersensitivity to epicutaneous antigens derived from components of the fungus. Atrophic pityriasis versicolor is a benign disease, but needs to be distinguished from other more severe skin diseases manifesting with cutaneous atrophy. Read More

    Itraconazole-induced thrombocytopenia.
    Cutan Ocul Toxicol 2017 Sep 21;36(3):305-306. Epub 2016 Dec 21.
    a Bahcesehir University, Faculty of Medicine, Department of Dermatology , Istanbul , Turkey , and.
    Itraconazole is one of the systemic treatment options for extensive tinea versicolor. A male patient who developed thrombocytopenia during the treatment of tinea versicolor by itraconazole is reported in this manuscript. He was diagnosed to develop thrombocytopenia on the third day of treatment. Read More

    A clinical study of cutaneous changes in pregnancy.
    J Epidemiol Glob Health 2017 Mar 19;7(1):63-70. Epub 2016 Nov 19.
    Department of Dermatology, Government Medical College, Alappuzha, Kerala, India.
    Background/objective: Pregnant women experience a myriad of physiological and metabolic changes that affect different organ systems in the body. Cutaneous and appendageal alterations that manifest during pregnancy are largely modulated by hormonal, immunologic, and metabolic factors. Detailed reports encompassing physiological changes and specific dermatoses of pregnancy and effects of various dermatoses on pregnant women are scanty in literature. Read More

    Atrophying pityriasis versicolor as an idiosyncratic T cell-mediated response to Malassezia: A case series.
    J Am Acad Dermatol 2017 Apr 2;76(4):730-735. Epub 2016 Nov 2.
    Weill Cornell Medical College, Manhattan, New York. Electronic address:
    Background: Atrophying pityriasis versicolor (PV), first described in 1971, is a rare variant in which lesions appear atrophic.

    Objective: We sought to determine the pathophysiology of atrophying PV.

    Methods: A retrospective chart review identified 6 cases of atrophying PV. Read More

    A survey of herbal weeds for treating skin disorders from Southern Thailand: Songkhla and Krabi Province.
    J Ethnopharmacol 2016 Dec 28;193:574-585. Epub 2016 Sep 28.
    Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
    Ethnopharmacological Relevance: Skin diseases are common health problems which affecting to all ages. In Thailand, the number of patients diagnosed with skin diseases is increasing every year. Nowadays, The Ministry of Public Health is supporting and promoting herbs for treating various disorders, including disorders of the skin to reduce the problem of antibiotic resistance and adverse drug reactions. Read More

    Dermoscopy in General Dermatology: A Practical Overview.
    Dermatol Ther (Heidelb) 2016 Dec 9;6(4):471-507. Epub 2016 Sep 9.
    Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.
    Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. Read More

    Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan.
    Med Mycol J 2016 ;57(3):E63-6
    Department of Dermatology, Teikyo University Hospital.
    Topical or systemic antifungal therapy was administered to patients diagnosed with Malassezia folliculitis during the 5-year period between March 2007 and October 2013. The diagnosis of Malassezia folliculitis was established on the basis of characteristic clinical features and direct microscopic findings (10 or more yeast-like fungi per follicle). Treatment consisted of topical application of 2% ketoconazole cream or 100 mg oral itraconazole based on symptom severity and patients' preferences. Read More

    Comparative clinical trial: fluconazole alone or associated with topical ketoconazole in the treatment of pityriasis versicolor.
    Tunis Med 2016 Feb;94(2):107-11
    Background: The efficacy of ketoconazole and fluconazole in pityriasis versicolor had been proved.

    Aim: To compare the efficacy and the safety of two doses of fluconazole given 1 week apart alone or associated to ketoconazole shampoo.

    Methods: Our study included all patients with pityriasis versicolor who attended in dermatology department of Habib Thameur Hospital, Tunis (over a 21-month period). Read More

    The evaluation of local oxidative/nitrosative stress in patients with pityriasis versicolor: a preliminary study.
    Mycoses 2016 Nov;59(11):720-725
    Department of Dermatology, Faculty of Medicine, Sutcu Imam University, Kahramanmaras, Turkey.
    Yeast of Malassezia, members of the microbiologic flora of the skin, cause pityriasis versicolor and have also been implicated in the pathogenesis of other superficial dermatoses. The mechanisms by which the yeast cause these dermatoses, however, are not yet clear, and there have been no studies on the interaction between fungi and keratinocytes, especially the effects of fungi on the production of reactive oxygen/nitrogen species by human keratinocytes. This is the first study we aimed to evaluate the role of oxidative/nitrosative stress in affected skin areas in patients with pityriasis versicolor. Read More

    Oral Antifungal Drugs in the Treatment of Dermatomycosis.
    Med Mycol J 2016 ;57(2):J71-5
    Department of Dermatology, Tokyo Women's Medical University.
    Oral antifungal drugs are used primarily to treat tinea unguium; however, they are also useful for other types of tinea. For example, a combination of topical and oral antifungal drugs is effective in hyperkeratotic tinea pedis that is unresponsive to topical monotherapy. In cases of tinea facialis adjacent to the eyes, ears, or mouth, or widespread tinea corporis, or tinea cruris involving the complex skin folds of the external genitalia, it is difficult to apply topical drugs to all the lesions; therefore, oral antifungal drugs are necessary. Read More

    Clinicomycological profile of pityriasis versicolor in Assam.
    Indian J Pathol Microbiol 2016 Apr-Jun;59(2):159-65
    Department of Microbiology, Gauhati Medical College, Guwahati, Assam, India.
    Background: Geographical variation in the distribution of Malassezia species associated with pityriasis versicolor (PV) has led to the necessity of studying epidemiological, mycological, and clinical characteristics of PV.

    Aims: To study the epidemiological, mycological, and clinical characteristics of PV in a tertiary care hospital.

    Settings And Design: The study was carried out with a cross-sectional design. Read More

    Confluent and Reticulated Papillomatosis of Gougerot-Carteaud on Black Skin: Two Observations.
    Case Rep Dermatol Med 2016 5;2016:2507542. Epub 2016 Apr 5.
    Department of Dermatology and Venerology, Teaching Hospital of Treichville, BP 3, Abidjan, Côte d'Ivoire.
    Confluent and reticulated papillomatosis of Goujerot-Carteaud is a rare and benign skin disease characterized by flat papules taking a reticulated appearance. It is a skin disease of unknown etiology and nosology that is always discussed. This disease preferentially involves the chest and interscapular regions. Read More

    Mycological Considerations in the Topical Treatment of Superficial Fungal Infections.
    J Drugs Dermatol 2016 Feb;15(2 Suppl):s49-55
    Trichophyton rubrum remains the most common pathogenic dermatophyte in the United States, Europe, and industrialized Asia, although other species are predminant elsewhere. Candida albicans is the most common pathogenic yeast, with other species occasionally encountered. Just a few of the 14 described species of Malassezia cause pityriasis versicolor worldwide. Read More

    Dermatological Complaints of the Elderly Attending a Dermatology Outpatient Clinic in Turkey: A Prospective Study over a One-year Period.
    Acta Dermatovenerol Croat 2015 ;23(4):277-81
    Assoc. Prof. Muhterem Polat, MD, Gazi University School of Medicine, Department of Dermatology, Ankara, Turkey;
    The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Read More

    Malassezia species in healthy skin and in dermatological conditions.
    Int J Dermatol 2016 May 29;55(5):494-504. Epub 2015 Dec 29.
    Institute of Pathology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
    The genus Malassezia comprises lipophilic species, the natural habitat of which is the skin of humans and other warm-blooded animals. However, these species have been associated with a diversity of dermatological disorders and even systemic infections. Pityriasis versicolor is the only cutaneous disease etiologically connected to Malassezia yeasts. Read More

    [2011 Epidemiological Survey of Dermatomycoses in Japan].
    Med Mycol J 2015 ;56(4):J129-35
    Epidemiological Investigation Committee for Human Mycoses in the Japanese Society for Medical Mycology, Chairman and Reporter.
    An epidemiological survey of dermatomycoses and their causative fungus flora in Japan for 2011 was conducted in accordance with methods and criteria of the past four surveys. The survey covered a total number of 36,052 outpatients who visited 12 dermatological clinics throughout Japan. The results were as follows. Read More

    Superficial Fungal Infections.
    Prim Care 2015 Dec;42(4):501-16
    Division of Primary Care, Family Medicine, Mayo Clinic Health System, 1921 Alice Street, Waycross, GA 31501, USA.
    Superficial fungal infections grow in dark and moist areas and invade various parts of the body. These infections are easily treatable in immunocompetent individuals. In immunosuppressed individuals, the presentation can be quite severe, requiring use of more potent antifungal agents. Read More

    The effects of the El Niño Southern Oscillation on skin and skin-related diseases: a message from the International Society of Dermatology Climate Change Task Force.
    Int J Dermatol 2015 Dec 15;54(12):1343-51. Epub 2015 Oct 15.
    Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.
    The El Niño Southern Oscillation (ENSO) is a complex climate phenomenon occurring in the Pacific Ocean at intervals of 2-7 years. The term refers to fluctuations in ocean temperatures in the tropical eastern Pacific Ocean (El Niño [the warm phase of ENSO] and La Niña [the cool phase of ENSO]) and in atmospheric pressure across the Pacific basin (Southern Oscillation). This weather pattern is attributed with causing climate change in certain parts of the world and is associated with disease outbreaks. Read More

    SIXTEEN YEARS OF PITYRIASIS VERSICOLOR IN METROPOLITAN AREA OF PORTO ALEGRE, SOUTHERN BRAZIL.
    Rev Inst Med Trop Sao Paulo 2015 Jul-Aug;57(4):277-80
    Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BR.
    Pityriasis versicolor is the most common of the diseases caused by Malassezia yeasts. The aim of this study is to determine the prevalence of pityriasis versicolor and its etiological aspects in the metropolitan area of Porto Alegre, Brazil. A retrospective cross-sectional study with data from patients of a reference hospital from 1996 to 2011 was performed. Read More

    A randomized double-blind, non-inferiority Phase II trial, comparing dapaconazole tosylate 2% cream with ketoconazole 2% cream in the treatment of Pityriasis versicolor.
    Expert Opin Investig Drugs 2015 30;24(11):1399-407. Epub 2015 Sep 30.
    a 1 State University of Campinas (UNICAMP), Faculty of Medical Sciences, Department of Pharmacology , Campinas, SP, Brazil.
    Objectives: The objective of this research was to evaluate the efficacy of a new antifungal imidazole, dapaconazole tosylate, in the treatment of Pityriasis versicolor (PV).

    Design And Methods: Sixty patients with clinical and mycological diagnosis of PV were randomly assigned to receive either 1 g dapaconazole tosylate 2% cream or 1 g ketoconazole 2% cream. Treatments were applied once a day for 28 days. Read More

    Dermatophytes and other associated fungi in patients attending to some hospitals in Egypt.
    Braz J Microbiol 2015 Jul-Sep;46(3):799-805. Epub 2015 Jul 1.
    Dermatology Department, Faculty of Medicine, Cairo University, Giza, Egypt .
    Dermatophytes are keratinophilic fungi that infect keratinized tissues causing diseases known as dermatophytoses. Dermatophytes are classified in three genera, Epidermophyton, Microsporum, and Trichophyton. This investigation was performed to study the prevalence of dermatomycosis among 640 patients being evaluated at the dermatology clinics at Kasr elainy, El-Husein and Said Galal hospitals in Cairo and Giza between January 2005 and December 2006. Read More

    Malassezia Pneumonia: A Rare Complication of Parenteral Nutrition Therapy.
    JPEN J Parenter Enteral Nutr 2016 Nov 6;40(8):1194-1196. Epub 2015 Jul 6.
    Indiana University School of Medicine, Indianapolis, Indiana.
    Malassezia species (formerly known as Pityrosporum) are part of normal human skin flora and have been associated with benign dermatologic conditions, such as seborrheic dermatitis and tinea versicolor. In rare cases, however, Malassezia has been associated with systemic disease in immunocompromised patients and infants in the neonatal intensive care unit. Malassezia species require long-chain fatty acids for growth and therefore have a known predilection for individuals receiving lipid containing intravenous parenteral nutrition (PN). Read More

    Could nanovesicles containing a penetration enhancer clinically improve the therapeutic outcome in skin fungal diseases?
    Nanomedicine (Lond) 2015 2;10(13):2017-31. Epub 2015 Jul 2.
    Department of Pharmaceutics, Faculty of Pharmacy, October 6 University, Giza Governorate, Egypt.
    Aim: To study whether the formulation of an antifungal drug in nanovesicular form containing skin penetration enhancer would clinically modulate its therapeutic effectiveness.

    Materials & Methods: Nanovesicles containing different skin penetration enhancers 'PEVs' were prepared and loaded with sertaconazole. Penetration-enhancer vesicles were characterized for entrapment efficiency, particle size, zeta potential, elasticity, viscosity, morphology and ex vivo skin deposition. Read More

    Burden of serious fungal infections in the Dominican Republic.
    J Infect Public Health 2016 Jan-Feb;9(1):7-12. Epub 2015 May 28.
    The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; The University Hospital of South Manchester, National Aspergillosis Centre (NAC), Manchester, UK.
    The Dominican Republic (DR) is the second largest Caribbean nation and, with Haiti, the DR accounts for nearly three-quarters of the cases of human immunodeficiency virus (HIV) infection in the Caribbean region and the highest rates of TB in the Americas. The present study estimated the burden of serious fungal infections and some other mycoses in the DR. The data were extracted from the World Health Organization Stop Tuberculosis (WHO STOP TB) program, the Joint United Nations Program on HIV/AIDS (UNAIDS), and searches for relevant literature via MEDLINE, PubMed, MedFacts, and so on. Read More

    [Cutaneous Malassezia infections and Malassezia associated dermatoses: An update].
    Hautarzt 2015 Jun;66(6):465-84; quiz 485-6
    Labor für medizinische Mikrobiologie, Partnerschaft Prof. Dr. med. Pietro Nenoff & Dr. med. Constanze Krüger, Straße des Friedens 8, 04579, Mölbis, Deutschland,
    The lipophilic yeast fungus Malassezia (M.) spp. is the only fungal genus or species which is part of the physiological human microbiome. Read More

    Mycology - an update Part 3: Dermatomycoses: topical and systemic therapy.
    J Dtsch Dermatol Ges 2015 May;13(5):387-410; quiz 411
    Medical Microbiology Laboratory, Mölbis, Germany.
    Treatment of dermatophyte infections is based on the clinical picture and mycological detection of the causative pathogen. Based on the appropriate indication, onychomycosis can be treated topically using an antimycotic nail lacquer. Atraumatic nail abrasion with 40 % urea ointment has a beneficial effect on healing. Read More

    The Rise and Fall of Oral Ketoconazole.
    J Cutan Med Surg 2015 Jul-Aug;19(4):352-7. Epub 2015 Mar 5.
    Mediprobe Research Inc., London, Ontario, Canada.
    Background: Ketoconazole was the first broad-spectrum oral antifungal agent available to treat systemic and superficial mycoses. Evidence of hepatotoxicity associated with its use emerged within the first few years of its approval. Growing evidence of serious side effects including endocrine dysregulation, several drug interactions, and death led to the review of oral ketoconazole in 2011. Read More

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