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    Dermatitis of the Foot: Epidemiologic and Clinical Features in 389 Children.
    Pediatr Dermatol 2017 Jul 21. Epub 2017 Jul 21.
    Dermatology Department, Valencia University General Hospital, Valencia, Spain.
    Background/objectives: Footwear dermatitis is a form of contact dermatitis resulting from exposure to shoes. There have been only small studies regarding foot contact dermatitis in children. The present study was undertaken to define the prevalence and epidemiologic and clinical features of shoe dermatitis in children. Read More

    Epidemiological survey of dermatophytosis in Damascus, Syria, from 2008 to 2016.
    Curr Med Mycol 2016 Sep;2(3):32-36
    Department of Microbiology, Faculty of pharmacy, Arab international university (AIU), Ghabaghib, Daraa Governorate, Syria.
    Background And Purpose: It is important to follow annually the probable changes in distribution pattern of dermatophytosis and its etiological agents in different communities. In this study, we determined the prevalence of dermatophytosis and its causative agents in Damascus, Syria, between 2008 and 2016.

    Materials And Methods: A total of 4080 outpatients who visited the dermatological clinics in Damascus, were evaluated. Read More

    Analysis on curative effects and safety of 2% liranaftate ointment in treating tinea pedis and tinea corporis & cruris.
    Pak J Pharm Sci 2017 May;30(3(Special)):1103-1106
    Xinjiang Medical University, Wulumuqi, China.
    The paper is intended to analyze and evaluate the specific curative effect and safety of 2% liranaftate ointment in treating patients with tinea pedis and tinea cruris. 1,100 cases of patients with tinea pedis and tinea corporis & cruris were selected as research objects and were divided into two groups according to the random number table method. They were treated with different methods: 550 cases of patients were treated with 2% liranaftate ointment for external use in the observation group and the rest 550 cases of patients were treated with 1% bifonazole cream in the control group. Read More

    Dermatophyte Antigen Kit.
    Med Mycol J 2017 ;58(2):J51-J54
    Department of Dermatology, Tokyo Women's Medical University.
    The dermatophyte antigen kit uses monoclonal antibodies that react with polysaccharides present in the dermatophyte cell wall to detect dermatophyte antigens in specimens based on the principle of immunochromatography. Clinical studies showed that the kit was very useful in the diagnosis of tinea unguium but not tinea pedis. The kit was therefore further developed as an in vitro diagnostic tool for tinea unguium and was approved by the Pharmaceuticals and Medical Devices Agency of Japan. Read More

    Treatment of Tinea Pedis in Elderly Patients Using External Preparations.
    Med Mycol J 2017 ;58(2):J35-J41
    Division of Hospital Pharmacy, Kyoundo Hospital.
    Infection rate of tinea pedis is high in the elderly, wherein treatment by a dermatologist should be considered to prevent infecting their family members. About 90 percent of cases with tinea pedis is treated only using external preparations. In treating the elderly with tinea pedis using external preparation, we should take into consideration that the elderly have thinner and weaker skin compared to younger people. Read More

    Antimicrobial activity of puffball(Bovistella radicata) and separation of bioactive compounds.
    AMB Express 2017 Dec 19;7(1):99. Epub 2017 May 19.
    School of Food Science and Engineering, Hefei University of Technology, 124 ShenHua Building, 193rd TunXi Road, Hefei, 230009, Anhui, China.
    Background: To test the antimicrobial activity of different extracts and fermentation broth from puffball(Bovistella radicata), the different extracts and fermentation broth of puffball were prepared, the active fraction was investigated by UPLC-UV-MS and semi-preparative chromatograph.

    Results: Through zones of inhibition (ZOI) and minimum inhibitory concentrations (MIC) tests, the supernatant of fermentation possessed best antimicrobial activity in all extracts whose MIC value is 31.2 μg/ml against T. Read More

    The survey of tinea capitis and scalp dermatophyte carriage in nursing home residents.
    Med Mycol 2017 May 18. Epub 2017 May 18.
    Department of Dermatology, Chang Gung Memorial Hospital, Linkou and Taipei, Taiwan.
    Tinea capitis is a contagious dermatophyte infection of scalp and associated hairs. On the other hand, asymptomatic carriage is a status of positive dermatophyte scalp culture, but without signs or symptoms of tinea capitis, and no evidence of hair shaft invasion confirmed by direct microscopy. Tinea capitis and asymptomatic carriage mostly occur in children, but adult females are becoming another population in recent decades. Read More

    Interdigital melanoma simultaneously affecting two neighboring interdigital spaces : First description in the medical literature.
    Wien Med Wochenschr 2017 Apr 24. Epub 2017 Apr 24.
    Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Friedrichstrasse 41, 01067, Dresden, Germany.
    Background: Interdigital melanoma, as a subtype of acral lentiginous melanoma, is relatively uncommon in the Caucasian population. It frequently goes unrecognized for a prolonged period of time prior to diagnosis, due to its asymptomatic nature and variable clinical appearance.

    Methods: We report the case of a 67-year-old Caucasian woman who presented with interdigital malignant melanoma affecting two neighboring interdigital spaces. Read More

    High prevalence of superficial white onychomycosis by Trichophyton interdigitale in a Japanese nursing home with a geriatric hospital.
    Mycoses 2017 Apr 24. Epub 2017 Apr 24.
    Department of Dermatology, Kanazawa Medical University, Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa, Japan.
    A mycological survey on feet was performed in a nursing home with a geriatric hospital to ascertain the prevalence of tinea lesions. Of 100 subjects, comprising 62 in the nursing home and 38 in the geriatric wing, 70 were diagnosed with tinea pedis, tinea unguium (onychomycosis) or both of which 54 had onychomycosis alone, nine tinea pedis alone and seven had co-existing onychomycosis and tinea pedis. The most common clinical type of onychomycosis was distal lateral subungual onychomycosis (DLSO) at 30 cases, followed by superficial white onychomycosis (SWO) at 23 cases. Read More

    Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene.
    Antimicrob Agents Chemother 2017 Jul 27;61(7). Epub 2017 Jun 27.
    Service de Dermatologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Terbinafine is one of the allylamine antifungal agents whose target is squalene epoxidase (SQLE). This agent has been extensively used in the therapy of dermatophyte infections. The incidence of patients with tinea pedis or unguium tolerant to terbinafine treatment prompted us to screen the terbinafine resistance of all Trichophyton clinical isolates from the laboratory of the Centre Hospitalier Universitaire Vaudois collected over a 3-year period and to identify their mechanism of resistance. Read More

    Dermatological comorbidity in psoriasis: results from a large-scale cohort of employees.
    Arch Dermatol Res 2017 Jul 12;309(5):349-356. Epub 2017 Apr 12.
    German Center for Health Services Research in Dermatology (CVderm), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    The field of dermatological comorbidity in psoriasis is only passively explored with contradictory results. Objective of this study was to further investigate the complex field of psoriasis and associated skin diseases by identifying skin comorbidity patterns in an extensive cohort of employees in Germany. Retrospective analysis of data deriving from occupational skin cancer screenings was conducted. Read More

    Examining the accuracy of visual diagnosis of tinea pedis and tinea unguium in aged care facilities.
    J Wound Care 2017 Apr;26(4):179-183
    Professor, Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
    Objective: The aim of this study was to examine the accuracy of visual diagnosis of tinea pedis (Athlete's foot) and tinea unguium (fungal nail infection), as well as to provide information on skin abnormalities that could help identify these diseases in aged care facilities (long-term care facilities (LTCFs) and nursing homes).

    Method: A multicentre, cross-sectional observational study was conducted in a LTCF and two nursing homes. A dermatologist observed the skin abnormalities in the participants' interdigital and plantar areas, to screen for tinea pedis, and in the participants' toenails, to screen for tinea unguium. Read More

    Prescribing Pattern of Antifungal Medications at a Tertiary Care Hospital in Oman.
    J Clin Diagn Res 2016 Dec 1;10(12):FC27-FC30. Epub 2016 Dec 1.
    Biomedical Scientist, Department of Pathology, Sultan Qaboos University , Al Khodh, Oman .
    Introduction: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs.

    Aim: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman. Read More

    Single-nucleotide polymorphism in a local population of Trichophyton rubrum.
    Med Mycol 2017 Feb 16. Epub 2017 Feb 16.
    Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.
    Trichophyton rubrum is an important causative agent of superficial mycoses worldwide. To uncover a genetic composition of a local population of this fungus, we sequenced A7C99_6411 and A7C99_6714 loci, coding for hypothetical proteins and revealed two complex genotypes, differing by a single missense mutation in each locus. One of the two A7C99_6411/6714 genotypes was not found in tinea pedis cases and demonstrated mostly longer TRS-1 elements when compared to another genotype. Read More

    Incidence and biodiversity of yeasts, dermatophytes and non-dermatophytes in superficial skin infections in Assiut, Egypt.
    J Mycol Med 2017 Jun 7;27(2):166-179. Epub 2017 Feb 7.
    Department of Botany and Microbiology, Faculty of Science, Assiut University Mycological Centre, Assiut University, Assiut, Egypt.
    Objective: The aim was to identify the incidence of the causal agents from dermatophytes, non-dermatophytes and yeasts in Assiut Governorate employing, beside the morphological and physiological techniques, the genotypic ones.

    Patients: Samples from infected nails, skin and hair were taken from 125 patients.

    Materials And Methods: Patients who presented with onychomycosis, tinea capitis, tinea corporis, tinea cruris and tinea pedis during the period from February 2012 to October 2015 were clinically examined and diagnosed by dermatologists and were guided to Assiut University Mycological Centre for direct microscopic examination, culturing and identification. Read More

    Computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes.
    Bioinformation 2016 15;12(3):197-201. Epub 2016 Jun 15.
    Biotechnology Branch, University Institute of Engineering and Technology (U.I.E.T), Punjab University, Chandigarh 160014, India.
    Dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. The infection known as dermatophytosis, caused by members of the genera Microsporum, Trichophyton, and Epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea corporis), nail (tinea unguium), and hand (tinea manuum). The identification of evolutionary relationship between these three genera of dermatophyte is epidemiologically important to understand their pathogenicity. Read More

    Relationship Between Phenotypic and Genotypic Characteristics of Trichophyton mentagrophytes Strains Isolated from Patients with Dermatophytosis.
    Mycopathologia 2017 Jun 18;182(5-6):487-493. Epub 2017 Jan 18.
    Parasitology-Mycology Laboratory, Faculty of Medicine, Farhat Hached University Hospital, Mohamed El Karoui Street, 4002, Sousse, Tunisia.
    According to epidemiological, clinical and mycological criteria, it has long been admitted that the Trichophyton mentagrophytes species includes two varieties: a zoophilic variety (var. mentagrophytes) and an anthropophilic variety (var. interdigitale) that involve the upper and the lower part of the body, respectively. Read More

    Trichophyton rubrum Infection Characterized by Majocchi's Granuloma and Deeper Dermatophytosis: Case Report and Review of Published Literature.
    Mycopathologia 2017 Jun 21;182(5-6):549-554. Epub 2016 Dec 21.
    Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
    Infections caused by Trichophyton rubrum are very common in dermatological disease. It most often appears as superficial cutaneous mycosis, such as tinea manuum, tinea pedis, and tinea corporis. However, deep infection caused by T. Read More

    Acral manifestations of fungal infections.
    Clin Dermatol 2017 Jan - Feb;35(1):28-39. Epub 2016 Sep 10.
    Cerrahpaşa Medical Faculty, Department of Dermatology, İstanbul University, Fatih, Istanbul 34098, Turkey.
    Fungal infections, which are named according to the body site involved, can affect any skin area, the fingernails, or the toenails. Numerous fungal agents are responsible for both superficial and deep fungal diseases. Dermatophytes and Candida spp are the most common causative organisms on the surface of the hands, feet, and nails of patients with superficial fungal diseases; however, although deep fungal infections of the skin are less common compared with superficial fungal diseases, their incidence is increasing worldwide due to cross-border travel. Read More

    Foot Conditions among Homeless Persons: A Systematic Review.
    PLoS One 2016 9;11(12):e0167463. Epub 2016 Dec 9.
    Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
    Introduction: Foot problems are common among homeless persons, but are often overlooked. The objectives of this systematic review are to summarize what is known about foot conditions and associated interventions among homeless persons.

    Methods: A literature search was conducted on MEDLINE (1966-2016), EMBASE (1947-2016), and CINAHL (1982-2016) and complemented by manual searches of reference lists. Read More

    Epidemiology of Dermatophytoses in Crete, Greece.
    Med Mycol J 2016 ;57(4):E69-E75
    Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine.
    Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. Read More

    Risk factors for nonpurulent leg cellulitis: a systematic review and meta-analysis.
    Br J Dermatol 2016 Nov 18. Epub 2016 Nov 18.
    Emergency Care Research Unit (ECRU), Division of Population Health Sciences (PHS), Royal College of Surgeons in Ireland (RCSI), 123 St Stephens Green, Dublin 2, Ireland.
    Nonpurulent cellulitis is an acute bacterial infection of the dermal and subdermal tissues that is not associated with purulent drainage, discharge or abscess. The objectives of this systematic review and meta-analysis were to identify and appraise all controlled observational studies that have examined risk factors for the development of nonpurulent cellulitis of the leg (NPLC). A systematic literature search of electronic databases and grey literature sources was performed in July 2015. Read More

    Sprint Start Kinetics of Amputee and Non-Amputee Sprinters.
    PLoS One 2016 15;11(11):e0166219. Epub 2016 Nov 15.
    Institute of Biomechanics and Orthopaedics, German Sport University Cologne, Cologne, Germany.
    The purpose of this study was to explore the relationship between the forces applied to the starting blocks and the start performances (SPs) of amputee sprinters (ASs) and non-amputee sprinters (NASs). SPs of 154 male and female NASs (100-m personal records [PRs], 9.58-14. Read More

    Onychomycosis: Practical Approaches to Minimize Relapse and Recurrence.
    Skin Appendage Disord 2016 Sep 14;2(1-2):83-87. Epub 2016 Sep 14.
    Department of Dermatology, University of Alabama at Birmingham School of Medicine, Birmingham, Ala., USA.
    Introduction: Toenail onychomycosis is a common disease in which treatment options are limited and treatment failures and disease recurrence are frequently encountered. It usually requires many months of treatment, and recurrence may occur in more than half of the patients within 1 year or more after the infection has been eradicated. Data on long-term treatment, follow-up and recurrence are limited. Read More

    Enhancement of the topical tolnaftate delivery for the treatment of tinea pedis via provesicular gel systems.
    J Liposome Res 2016 Oct 19:1-11. Epub 2016 Oct 19.
    a Department of Pharmaceutical Technology , National Research Center , Cairo , Egypt.
    Tolnaftate is a thiocarbamate antifungal drug which is therapeutically active against dermatophytes that cause various forms of tinea. Due to the small amount of tolnaftate released from ordinary ointment bases and insufficient penetration through the infected skin layers the need to incorporate the drug in a more suitable pharmaceutical form has evolved. A provesicular system is one such form that can solve these problems. Read More

    Prevalence and epidemiology of tinea pedis and toenail onychomycosis and antifungal susceptibility of the causative agents in patients with type 2 diabetes in Turkey.
    Int J Dermatol 2017 Jan 26;56(1):68-74. Epub 2016 Sep 26.
    Department of Dermatology, Eskisehir State Hospital, Eskisehir, Turkey.
    Background: Diabetes patients are particularly susceptible to fungal infections because their vascular and immunological systems are compromised.

    Objectives: The present study aimed to determine prevalences of tinea pedis and onychomycosis, factors predisposing to their development, and antifungal susceptibilities of causative fungal species against fluconazole, itraconazole, and terbinafine in patients with type 2 diabetes mellitus (DM).

    Methods: Study groups were defined according to hemoglobin A1C rates of ≥6. Read More

    Tinea pedis and onychomycosis frequency in diabetes mellitus patients and diabetic foot ulcers. A cross sectional - observational study.
    Pak J Med Sci 2016 Jul-Aug;32(4):891-5
    Prof. Dr. Tamer Tetiker, M.D. Specialist in Internal Medicine and Endocrinology, Department of Internal Medicine, Division of Endocrinology, Cukurova University Medical Faculty, 01330 Adana, Turkey.
    Objective: Impaired cellular immunity and reduced phagocytic function of polymorphonuclear leukocytes facilitate the development of skin fungal and bacterial infections due to uncontrolled hyperglycemia in diabetic patients. In our study, we aimed to assess onychomycosis and/or tinea pedis frequency in diabetic patients, and effects on the development of chronic complications, particularly foot ulcer.

    Methods: We included 227 diabetic patients in the study. Read More

    Econazole Nitrate Foam 1% Improves the Itch of Tinea Pedis.
    J Drugs Dermatol 2016 Sep;15(9):1111-4
    Econazole nitrate topical foam, 1%, is indicated for the treatment of interdigital tinea pedis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum in patients 12 years of age and older. The symptom of itch or pruritus was evaluated in two randomized, double-blind, parallel-group, vehicle-controlled, multicenter Phase III studies in which econazole foam was compared with foam vehicle in subjects with interdigital tinea pedis. A thin, uniform layer of study treatment was applied once daily to all clinically affected interdigital regions of both feet for four weeks. Read More

    [Causative agents of superficial mycoses isolated in Dakar, Senegal: Retrospective study from 2011 to 2015].
    J Mycol Med 2016 Dec 31;26(4):368-376. Epub 2016 Aug 31.
    Laboratoire de parasitologie-mycologie, CHU Aristide Le Dantec, BP 5005, Dakar, Sénégal; Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontologie, université Cheikh Anta Diop, BP 16477, Dakar, Sénégal.
    Introduction: Superficial fungal infections, particularly of the skin, scalp and nails are very common and have been reported worldwide. The most common causative agents of these mycoses are dermatophytes, yeasts and molds. However, these agents vary with time and depend on many factors including the geography. Read More

    Tinea and Onychomycosis.
    Semin Cutan Med Surg 2016 Jun;35(6 Suppl):S110-3
    Professor of Dermatology Baylor College of Medicine Houston, Texas.
    Onychomycosis and tinea pedis are common fungal infections affecting the nails and feet, respectively. Two newly approved topical agents for onychomycosis are efinaconazole and tavaborole, both of which have demonstrated respectable cure rates in clinical studies. For tinea pedis, naftifine 2% and luliconazole 1% are new agents, both administered for relatively short courses, that may foster greater adherence Semin Cutan Med Surg 35(supp6):S110-S113. Read More

    Epidemiological trends of dermatophytosis in Tehran, Iran: A five-year retrospective study.
    J Mycol Med 2016 Dec 9;26(4):351-358. Epub 2016 Aug 9.
    Department of Medical Mycology, Pasteur Institute of Iran, Tehran 13164, Iran. Electronic address:
    Objective: Dermatophytosis is the most frequent fungal infection all over the world and its frequency is constantly increasing. The aim of this study was to evaluate clinical features and epidemiological trends of dermatophytosis over the years 2010 to 2014 in Tehran, Iran.

    Patients And Methods: A total of 13,312 patients clinically suspected of cutaneous fungal infections were examined. Read More

    Isolation, Identification, and In Vitro Antifungal Susceptibility Testing of Dermatophytes from Clinical Samples at Sohag University Hospital in Egypt.
    Electron Physician 2016 Jun 25;8(6):2557-67. Epub 2016 Jun 25.
    Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Egypt.
    Aim: The objective of this study was to isolate, identify, and explore the in-vitro antifungal susceptibility pattern of dermatophytes isolated from clinically suspected cases of dermatophytosis (tinea infections) attending the Dermatology Outpatient Clinic.

    Methods: This study was conducted at Sohag University Hospital from December 2014 to December 2015. Clinical samples (e. Read More

    Genetic Predictors of Susceptibility to Dermatophytoses.
    Mycopathologia 2017 Feb 8;182(1-2):67-76. Epub 2016 Aug 8.
    UMKC School of Medicine, Kansas City, MO, USA.
    Countless observational studies conducted over the last century reveal that dermatophytes infect humans of every age, race, gender, and socioeconomic status with strikingly high rates. The curious disparity in dermatophyte infection patterns observed within and between populations has led countless investigators to explore whether genetics underlie a susceptibility to, or confer protection against, dermatophyte infections. This paper examines the data that offer a link between genetics and dermatophytoses and discusses the underlying mechanisms that support these observations. Read More

    New Antifungal Agents and New Formulations Against Dermatophytes.
    Mycopathologia 2017 Feb 8;182(1-2):127-141. Epub 2016 Aug 8.
    Mediprobe Research Inc., 645 Windermere Road, London, ON, Canada.
    A variety of oral and topical antifungal agents are available for the treatment of superficial fungal infections caused by dermatophytes. This review builds on the antifungal therapy update published in this journal for the first special issue on Dermatophytosis (Gupta and Cooper 2008;166:353-67). Since 2008, there have not been additions to the oral antifungal armamentarium, with terbinafine, itraconazole, and fluconazole still in widespread use, albeit for generally more severe or recalcitrant infections. Read More

    Characterization of clinically important dermatophytes in North of Iran using PCR-RFLP on ITS region.
    J Mycol Med 2016 Dec 3;26(4):345-350. Epub 2016 Aug 3.
    Department of Biotechnology and Molecular Medicine, Arak University of Medical Sciences, Arak, Iran.
    Objective: Dermatophytosis is considered as one of the major public health problems in the world. Accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. In this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. Read More

    [Tinea in the genital area : A diagnostic and therapeutic challenge].
    Hautarzt 2016 Sep;67(9):689-99
    Department of Dermatology and Venerology, Medical University of Graz, Auenbruggerplatz 8, 8036, Graz, Österreich.
    Pubogenital tinea or tinea genitalis represents a rare type of dermatophytosis which, however, is increasingly being diagnosed. The mons pubis is affected, but also the outer regions to the penis shaft and the labia together with the groins. Pubogenital tinea is a more superficial erythrosquamous type, but strong inflammatory dermatomycoses of the genital area as tinea genitalis profunda ranging to kerion celsi are observed. Read More

    Tavaborole, Efinaconazole, and Luliconazole: Three New Antimycotic Agents for the Treatment of Dermatophytic Fungi.
    J Pharm Pract 2016 Aug 3. Epub 2016 Aug 3.
    College of Pharmacy, Ferris State University, Big Rapids, MI, USA
    Fungal diseases of the nail bed (onychomycosis) and epidermis are recurrent illnesses in the elderly and immunocompromised patients, which have few efficacious treatment options. Current treatment options for onychomycosis are limited to topical agents, laser treatment, and oral antifungals. Previous generations of topical agents were not efficacious, owing to poor penetration of the nail bed. Read More

    Epidemiology of onychomycosis in Serbia: a laboratory-based survey and risk factor identification.
    Mycoses 2017 Jan 29;60(1):25-32. Epub 2016 Jul 29.
    Faculty of Medicine, Institute of Microbiology and Immunology, University of Belgrade, Belgrade, Serbia.
    Onychomycosis is a fungal infection of the fingernails and/or toenails caused by dermatophytes, yeasts and non-dermatophyte moulds. The epidemiology of onychomycosis in Serbia is yet to be fully established. This epidemiological study was aimed at evaluating the epidemiology of onychomycosis in a sample of the Serbian patients at risk of onychomycosis, to determine the fungal aetiological agents and to identify the possible risk factors. Read More

    Skin disorders in peritoneal dialysis patients: An underdiagnosed subject.
    World J Nephrol 2016 Jul;5(4):372-7
    Meltem Gursu, Lamiye Yucel, Rumeyza Kazancioglu, Department of Nephrology, Bezmialem Vakif University Medical Faculty, 34093 Istanbul, Turkey.
    Aim: To examine all skin changes in peritoneal dialysis (PD) patients followed up in our unit.

    Methods: Patients on PD program for at least three months without any known chronic skin disease were included in the study. Patients with already diagnosed skin disease, those who have systemic diseases that may cause skin lesions, patients with malignancies and those who did not give informed consent were excluded from the study. Read More

    Increased Risk of Tinea Pedis and Onychomycosis Among Swimming Pool Employees in Netanya Area, Israel.
    Mycopathologia 2016 Dec 19;181(11-12):851-856. Epub 2016 Jul 19.
    Mediprobe Research Inc., 645 Windermere Road, London, ON, Canada.
    Tinea pedis and onychomycosis often co-occur in individuals. A relationship between swimming pools and tinea pedis exists; however, little research has investigated the relationship between onychomycosis, tinea pedis, and swimming pools. This study sought to examine the prevalence of tinea pedis and onychomycosis among swimming pool employees, a population that may be at risk of tinea infections. Read More

    Discovery of antifungal constituents from the Miao medicinal plant Isodon flavidus.
    J Ethnopharmacol 2016 Sep 20;191:372-378. Epub 2016 Jun 20.
    School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Kowloon, Hong Kong, China. Electronic address:
    Ethnopharmacological Relevance: Leigong Mountain is an area in the Southwest of China where there is a high incidence rate of athlete's foot, but the Miao people, a Chinese minority who reside in this mountainous area have suffered less from this disease due to their use of the herbal medicine Isodon flavidus (Hand.-Mazz.) H. Read More

    Oxygenated monoterpenes-rich volatile oils as potential antifungal agents for dermatophytes.
    Nat Prod Res 2017 Feb 16;31(4):460-464. Epub 2016 Jun 16.
    b CESPU - Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde , Gandra , Portugal.
    Essential oils (EOs) extracted from Lavandula luisieri and Cymbopogon citratus were tested for their antifungal activity against ten clinical isolates of dermatophytes isolated from cases of tinea pedis. Inhibition of conidial germination and antifungal drug/EO combination assay were tested on two ATCC reference strains of Trichophyton rubrum and Trichophyton mentagrophytes. EOs were characterised by high amount of oxygenated monoterpenes in their composition. Read More

    Oral Antifungal Drugs in the Treatment of Dermatomycosis.
    Med Mycol J 2016 ;57(2):J71-5
    Department of Dermatology, Tokyo Women's Medical University.
    Oral antifungal drugs are used primarily to treat tinea unguium; however, they are also useful for other types of tinea. For example, a combination of topical and oral antifungal drugs is effective in hyperkeratotic tinea pedis that is unresponsive to topical monotherapy. In cases of tinea facialis adjacent to the eyes, ears, or mouth, or widespread tinea corporis, or tinea cruris involving the complex skin folds of the external genitalia, it is difficult to apply topical drugs to all the lesions; therefore, oral antifungal drugs are necessary. Read More

    Polyclonality of Trichophyton rubrum Isolates in aDermatophytosis Patient with Multiple Lesions.
    Med Mycol J 2016 ;57(2):E17-20
    Department of Dermatology, Kanazawa Medical University.
    We cultured 15 isolates of Trichophyton rubrum and one isolate of Trichophyton mentagrophytes from an 82-year-old male tinea patient with multiple lesions. To determine whether feet lesions were the source of dermatophytes of other tinea lesions, we extracted total cellular DNA from the T. rubrum isolates(13 from feet, two from right waist and buttock). Read More

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