Search Our Scientific Publications & Authors

Antimicrob Agents Chemother 2021 Jun 7:AAC0032121. Epub 2021 Jun 7.

Vyome Therapeutics Limited, New Delhi, India.

Recalcitrant dermatophytic infections of the glabrous skin (tinea corporis/cruris/faciei) pose a huge challenge to healthcare systems. Combinations of oral and topical drugs may potentially improve cure rates but the same has never been objectively assessed for this condition in laboratory or clinical studies.The presentstudy was undertaken with an aim of identifying synergistic combinations of oral and topical antifungals by testing clinical isolates obtained from patients with recalcitrant tinea corporis/cruris. Read More

J Dtsch Dermatol Ges 2021 May 10. Epub 2021 May 10.

Department of Dermatology, Venereology, and Allergology, University Medical Center Göttingen, Göttingen, Germany.

Background And Objective: Dermatophyte infections of the skin and nails are common worldwide and vary between geographical areas and over time. The aim of this study was to determine the epidemiological profile of dermatophytes in Germany with a focus on comparing children with adults.

Patients And Methods: In this retrospective multicenter study, mycological dermatophyte culture results in the period 01/2014 to 12/2016 were analyzed according to identified pathogen, age and gender of patients, and type of disease. Read More

Folia Med (Plovdiv) 2021 Apr;63(2):292-296

Medical University of Plovdiv, Plovdiv, Bulgaria.

Tinea barbae profunda is a rare mycotic infection of the beard, caused by dermatophytic fungi. Patients with suppressed immune systems and severe comorbidities, such as diabetes mellitus, are more prone to this disease, but it could also be seen in agricultural workers and stockbreeders. The most frequent etiological agents of this infection are the zoophilic dermatophytes. Read More

J Cutan Aesthet Surg 2020 Oct-Dec;13(4):357-360

Department of DVL, GSL Medical College, Rajahmahendravaram, Andhra Pradesh, India.

Background: Cosmetic procedures are on the rise and practiced by all age groups, especially by teenagers. These procedures enhance the individual appearance and confidence levels, but they are not without side effects.

Aims And Objectives: The aim of this study was to evaluate the side effects occurring after various parlor procedures such as facials, threading, waxing, and laser hair reduction. Read More

Rev Argent Microbiol 2021 Apr 7. Epub 2021 Apr 7.

Microbiología, Laboratorio Central, Hospital Alemán, Ciudad Autónoma de Buenos Aires, Argentina.

Trichophyton benhamiae is a zoonotic dermatophyte that can cause tinea corporis, tinea faciei and tinea capitis, producing inflammatory lesions, especially in children. In this publication, we describe 7clinical cases of pediatric patients that occurred in our institution between July 2019 and January 2020. All patients underwent a conventional mycological study. Read More

Dermatol Online J 2021 Feb 15;27(2). Epub 2021 Feb 15.

Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka.

Indian J Dermatol Venereol Leprol 2021 Mar-Apr;87(2):154-175

Bhojani Clinic, Mumbai, Maharashtra, India.

Dermatophytosis has attained unprecedented dimensions in recent years in India. Its clinical presentation is now multifarious, often with atypical morphology, severe forms and unusually extensive disease in all age groups. We hesitate to call it an epidemic owing to the lack of population-based prevalence surveys. Read More

Med Mycol J 2021 ;62(1):1-4

Medical Mycology Research Center, Chiba University.

We present a 76-year-old Japanese male with tinea faciei, tinea corporis, and tinea unguium with dermatophytoma. We performed fungal culture and confirmed the causative fungus to be Trichophyton rubrum. We treated the patient using oral fosravuconazole l-lysine ethanolate (F-RVCZ). Read More

J Dermatol 2021 Apr 13;48(4):564-567. Epub 2021 Jan 13.

Department of Veterinary Dermatology, Nihon University College of Bioresource Sciences, Fujisawa, Kanagawa, Japan.

Terbinafine (TRF) has been used in the treatment of fungal infections for more than 20 years. Recently, TRF-resistant Trichophyton interdigitale and T. rubrum strains have been isolated from human patients worldwide. Read More

Mycopathologia 2021 Mar 4;186(1):119-125. Epub 2021 Jan 4.

Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Trichophyton benhamiae is a zoophilic dermatophyte mainly transmitted to humans from guinea pigs. This zoophilic species can also cause dermatophytosis as reported by human contact with other animals, such as rabbit, cat, and fox. Here, we report the tinea faciei and tinea corporis cases: a 12-year-old girl and her 53-year-old father, with no history of immunodeficiency and underlying disease, caused by T. Read More

Pediatr Dermatol 2021 Mar 18;38(2):520-521. Epub 2020 Dec 18.

Division of Pediatric Infectious Diseases, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.

Tinea faciei is a common pediatric skin disease, most often caused by fungi of the genus Trichophyton. T benhamiae has been recently reclassified as a distinct species and is recognized as an emerging zoonotic dermatophyte with a wide range of possible infectious reservoirs worldwide. We present a previously healthy 7-year-old child presenting with unusual inflammatory facial plaques due to T benhamiae, confirmed by mass spectroscopy. Read More

Clin Exp Dermatol 2021 Jan 12;46(1):190-193. Epub 2020 Nov 12.

Department of Microbiology, Bhagirathi Neotia Woman and Child Care Centre, Kolkata, India.

Rev Iberoam Micol 2020 Jul - Oct;37(3-4):94-96. Epub 2020 Sep 26.

Microbiology Department, Laboratori Clínic Metropolitana Nord, Hospital Germans Trias i Pujol, Department of Genetics and Microbiology, Autonomous University of Barcelona, Badalona, Spain; CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain.

Background: Dermatophytoses in children are common pathologies worldwide caused mainly by Trichophyton rubrum. However, due to the globalization and the atypical pets that people nowadays own, some zoonotic species are also involved in these lesions.

Case Report: We present two cases of tinea faciei caused by the zoonotic mould Trichophyton erinacei in two children that owned a guinea pig and a hedgehog, respectively. Read More

Indian Dermatol Online J 2020 Jul-Aug;11(4):502-519. Epub 2020 Jul 13.

Consultant Dermatologist, Dr. Kaushal's Skin Clinic, Agra, Uttar Pradesh, India.

Background And Aims: Dermatophytosis has always been a common superficial mycosis in India. However, the past 6-7 years have seen an unprecedented increase in the number of patients affected by recurrent, chronic, recalcitrant and steroid modified dermatophytosis involving the glabrous skin (tinea corporis, tinea cruris and tinea faciei). Importantly, there has been a notable decrease in clinical responsiveness to commonly used antifungals given in conventional doses and durations resulting in difficult-to-treat infections. Read More

Mycopathologia 2020 Aug 27;185(4):699-703. Epub 2020 Jul 27.

Department of Dermatology, Teikyo University Mizonokuchi Hospital, 5-1-1 Futako, Takatsu, Kawasaki, Kanagawa, Japan.

Nannizzia gypsea is a geophilic dermatophyte, previously known as Microsporum gypseum before renaming under the new taxonomy. This organism is distributed all over the world and is considered to be involved in keratin degradation in the soil. Generally, human infection involves direct contact with fertile soil. Read More

Mycoses 2020 Sep 15;63(9):970-978. Epub 2020 Jul 15.

Institute of Bacteriology and Mycology, Centre of Infectious Diseases, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.

Background: Dermatophytoses rank among the most frequent communicable diseases in humans, and the zoonotic transmission is increasing. The zoophilic dermatophyte Trichophyton (T.) benhamiae is nowadays one of the main causes of tinea faciei et corporis in children. Read More

J Cutan Med Surg 2020 Jun 22:1203475420936657. Epub 2020 Jun 22.

936657 Department of Dermatology, Hospital Regional Universitario de Málaga, Spain.

Br J Dermatol 2020 11 15;183(5):840-846. Epub 2020 Jun 15.

Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Background: Dermatophytic infections have undergone unprecedented changes in India in the recent past. Clinical trials to find out the effectiveness of the four main oral antifungal drugs are lacking.

Objectives: We tested the effectiveness of oral fluconazole, griseofulvin, itraconazole and terbinafine in chronic and chronic relapsing tinea corporis, tinea cruris and tinea faciei in an investigator-initiated, randomized, pragmatic trial. Read More

Indian J Dermatol Venereol Leprol 2020 Jun 8. Epub 2020 Jun 8.

Laboratory for Medical Microbiology, Partnership Prof. Pietro Nenoff and Dr. Constanze Krüger, Mölbis, Germany.

Nannizzia (N.) incurvata (formerly Microsporum incurvatum) represents a geophilic dermatophyte which has been previously classified as belonging to the species complex of N. gypsea (formerly Microsporum gypseum). Read More

J Dermatol 2020 Jun 15;47(6):615-621. Epub 2020 Apr 15.

Nagasaki Ekisaikai Hospital, Nagasaki, Japan.

The causative species of a total of 42 403 dermatophytosis cases that occurred during 1966-2015 were surveyed. The most prevalent clinical type was tinea pedis, followed by tinea unguium, corporis, cruris, manus, faciei and capitis. The prevalence of tinea faciei and capitis has increased since the late 1990s and the late 2000s, respectively. Read More

J Pediatr 2020 06 11;221:255-256. Epub 2020 Mar 11.

Department of Dermatology, Nationwide Children's Hospital, Columbus, Ohio.

BMC Infect Dis 2020 Feb 22;20(1):171. Epub 2020 Feb 22.

Department of Dermatology, Shanghai Changzheng Hospital, Second Affiliated Hospital of Naval Military Medical University, Shanghai, 200003, China.

Background: Trichophyton benhamiae is a zoophilic dermatophyte that can cause tinea in humans and animals. Lesions caused by T. benhamiae tend to be highly inflammatory, and patients are often infected by animals or other patients infected with T. Read More

An Bras Dermatol 2019 07 29;94(3):372-374. Epub 2019 Jul 29.

Dermatology Department, Clinical Hospital, School of Medicine, University of the Republic, Montevideo, Uruguay.

Curr Med Mycol 2019 Jun;5(2):16-21

Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.

Background And Purpose: Dermatophytes as the causative agents of dermatophytosis (ringworm) are widely spread around the world. Accurate identification of dermatophytes in one area can be particularly important for epidemiological studies. Regarding this, the aim of the present study was to describe the species spectrum of dermatophytes, isolated from patients in Mashhad city, Iran, using the molecular-based method. Read More

Arch Dis Child 2020 Sep 29;105(9):836. Epub 2019 Jun 29.

Department of Surgery and Translational Medicine, Division of Dermatology, University of Florence, Florence, Italy.

Indian Pediatr 2019 05;56(5):433

Department of Dermatology, Farhat Hached Hospital, Tunisia.

J Dermatolog Treat 2020 Nov 16;31(7):749-753. Epub 2019 May 16.

Department of Microbiology, Government Medical College and Hospital, Chandigarh, India.

There has been an alarming increase in recalcitrant dermatophytosis in recent years. The standard treatment guidelines no longer seem effective in achieving clearance and results in high failure rates. To evaluate the efficacy and safety of oral terbinafine and itraconazole combination therapy in the management of dermatophytosis. Read More

Cent Eur J Public Health 2018 Dec;26 Suppl:S72-S75

Department of Public Health and Hygiene, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Kosice, Slovak Republic.

Objective: A three-year retrospective study of fungi isolated from samples of patients with suspected fungal skin infections in Eastern Slovakia is presented.

Methods: A total of 11,989 samples were collected and investigated with direct microscopic examination using 20% KOH and cultivated in Sabouraud and Mycosel medium. Identification was based on macroscopic and microscopic characteristics. Read More

Iran J Public Health 2018 Dec;47(12):1930-1936

School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.

Background: Dermatophytosis is known as one of the most frequent cutaneous infections that lead to public health problems to human and animals. The purpose of this study was to determine the prevalence of human dermatophytosis due to zoophilic species in Tehran, Iran from 2014 to 2015.

Methods: Overall, 3989 patients with clinically suspected fungal infections were studied. Read More