Search our Database of Scientific Publications and Authors

I’m looking for a

    380 results match your criteria Tinea Cruris

    1 OF 8

    Clinico-mycological study of dermatophytic infections and their sensitivity to antifungal drugs in a tertiary care center.
    Indian J Dermatol Venereol Leprol 2017 Jul-Aug;83(4):436-440
    Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
    Background: Worldwide, dermatophytic infections are running a chronic course either due to ineffective treatment or emerging drug resistance. In the past three decades, there has been an increase in incidence and non-responsiveness to conventional antifungals, which suggests that there is a need of antifungal sensitivity testing.

    Aims: This study was aimed at identifying clinico-mycological pattern of dermatophytic infections in patients attending thedermatology outpatient department of a tertiary care hospital, and to obtain the sensitivity pattern of isolates against six commonly used oral antifungals (fluconazole, terbinafine, itraconazole, ketoconazole, griseofulvin and voriconazole). Read More

    Incidence and biodiversity of yeasts, dermatophytes and non-dermatophytes in superficial skin infections in Assiut, Egypt.
    J Mycol Med 2017 Jun 7;27(2):166-179. Epub 2017 Feb 7.
    Department of Botany and Microbiology, Faculty of Science, Assiut University Mycological Centre, Assiut University, Assiut, Egypt.
    Objective: The aim was to identify the incidence of the causal agents from dermatophytes, non-dermatophytes and yeasts in Assiut Governorate employing, beside the morphological and physiological techniques, the genotypic ones.

    Patients: Samples from infected nails, skin and hair were taken from 125 patients.

    Materials And Methods: Patients who presented with onychomycosis, tinea capitis, tinea corporis, tinea cruris and tinea pedis during the period from February 2012 to October 2015 were clinically examined and diagnosed by dermatologists and were guided to Assiut University Mycological Centre for direct microscopic examination, culturing and identification. Read More

    Computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes.
    Bioinformation 2016 15;12(3):197-201. Epub 2016 Jun 15.
    Biotechnology Branch, University Institute of Engineering and Technology (U.I.E.T), Punjab University, Chandigarh 160014, India.
    Dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. The infection known as dermatophytosis, caused by members of the genera Microsporum, Trichophyton, and Epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea corporis), nail (tinea unguium), and hand (tinea manuum). The identification of evolutionary relationship between these three genera of dermatophyte is epidemiologically important to understand their pathogenicity. Read More

    Efficacy and tolerability of topical sertaconazole versus topical terbinafine in localized dermatophytosis: A randomized, observer-blind, parallel group study.
    Indian J Pharmacol 2016 Nov-Dec;48(6):659-664
    Department of Pharmacology, Venerology and Leprosy, R. G. Kar Medical College and Hospital, Kolkata, West Bengal, India.
    Objective: Epidermal dermatophyte infections most commonly manifest as tinea corporis or tinea cruris. Topical azole antifungals are commonly used in their treatment but literature suggests that most require twice-daily application and provide lower cure rates than the allylamine antifungal terbinafine. We conducted a head-to-head comparison of the effectiveness of the once-daily topical azole, sertaconazole, with terbinafine in these infections. Read More

    Epidemiology of Dermatophytoses in Crete, Greece.
    Med Mycol J 2016 ;57(4):E69-E75
    Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine.
    Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. Read More

    Risk-Factors and Awareness of HPV in Turkish people with Anogenital Warts in Bagcilar district: a Cross-Sectional Study.
    Arch Iran Med 2016 Oct;19(10):715-719
    Erciyes University Faculty of Medicine, Department of Public Health, Kayseri, Turkey.
    Background: Anogenital warts (AGWs) are epithelial tumors which develop as a result of human papilloma virus (HPV) infection. We aimed to assess the sociodemographic, sexual and other possible risk-factors, and awareness of the HPV infection among Turkish people with AGW in the Bagcilar district of Istanbul.

    Methods: A cross-sectional study was conducted on 273 patients (183 men, 90 women) with AGW between October 2014 - March 2015. Read More

    Relapse after Oral Terbinafine Therapy in Dermatophytosis: A Clinical and Mycological Study.
    Indian J Dermatol 2016 Sep-Oct;61(5):529-33
    Department of Microbiology, Government Medical College, Srinagar, Jammu and Kashmir, India.
    Background: The incidence of recurrent tinea infections after oral terbinafine therapy is on the rise.

    Aim: This study aims to identify the appearance of incomplete cure and relapse after 2-week oral terbinafine therapy in tinea corporis and/or tinea cruris.

    Materials And Methods: A total of 100 consecutive patients clinically and mycologically diagnosed to have tinea corporis and/or tinea cruris were included in the study. Read More

    Epidemiological trends of dermatophytosis in Tehran, Iran: A five-year retrospective study.
    J Mycol Med 2016 Dec 9;26(4):351-358. Epub 2016 Aug 9.
    Department of Medical Mycology, Pasteur Institute of Iran, Tehran 13164, Iran. Electronic address:
    Objective: Dermatophytosis is the most frequent fungal infection all over the world and its frequency is constantly increasing. The aim of this study was to evaluate clinical features and epidemiological trends of dermatophytosis over the years 2010 to 2014 in Tehran, Iran.

    Patients And Methods: A total of 13,312 patients clinically suspected of cutaneous fungal infections were examined. Read More

    Isolation, Identification, and In Vitro Antifungal Susceptibility Testing of Dermatophytes from Clinical Samples at Sohag University Hospital in Egypt.
    Electron Physician 2016 Jun 25;8(6):2557-67. Epub 2016 Jun 25.
    Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Egypt.
    Aim: The objective of this study was to isolate, identify, and explore the in-vitro antifungal susceptibility pattern of dermatophytes isolated from clinically suspected cases of dermatophytosis (tinea infections) attending the Dermatology Outpatient Clinic.

    Methods: This study was conducted at Sohag University Hospital from December 2014 to December 2015. Clinical samples (e. Read More

    New Antifungal Agents and New Formulations Against Dermatophytes.
    Mycopathologia 2017 Feb 8;182(1-2):127-141. Epub 2016 Aug 8.
    Mediprobe Research Inc., 645 Windermere Road, London, ON, Canada.
    A variety of oral and topical antifungal agents are available for the treatment of superficial fungal infections caused by dermatophytes. This review builds on the antifungal therapy update published in this journal for the first special issue on Dermatophytosis (Gupta and Cooper 2008;166:353-67). Since 2008, there have not been additions to the oral antifungal armamentarium, with terbinafine, itraconazole, and fluconazole still in widespread use, albeit for generally more severe or recalcitrant infections. Read More

    Characterization of clinically important dermatophytes in North of Iran using PCR-RFLP on ITS region.
    J Mycol Med 2016 Dec 3;26(4):345-350. Epub 2016 Aug 3.
    Department of Biotechnology and Molecular Medicine, Arak University of Medical Sciences, Arak, Iran.
    Objective: Dermatophytosis is considered as one of the major public health problems in the world. Accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. In this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. Read More

    Tavaborole, Efinaconazole, and Luliconazole: Three New Antimycotic Agents for the Treatment of Dermatophytic Fungi.
    J Pharm Pract 2016 Aug 3. Epub 2016 Aug 3.
    College of Pharmacy, Ferris State University, Big Rapids, MI, USA
    Fungal diseases of the nail bed (onychomycosis) and epidermis are recurrent illnesses in the elderly and immunocompromised patients, which have few efficacious treatment options. Current treatment options for onychomycosis are limited to topical agents, laser treatment, and oral antifungals. Previous generations of topical agents were not efficacious, owing to poor penetration of the nail bed. Read More

    [Clinical problems in medical mycology: Problem number 50].
    Rev Iberoam Micol 2017 Jan - Mar;34(1):53-55. Epub 2016 Jul 19.
    Unidad Micología, Hospital de Infecciosas Francisco Javier Muñiz, Buenos Aires, Argentina. Electronic address:
    We present the case of a 34 year-old man, HIV-positive, who had suffered a disseminated histoplasmosis treated with amphotericin B one year before his admission. He was admitted at the Infectious Diseases Muñiz Hospital with a non-lithiasic chlolecystitis. During the clinical examination perigenital skin lesions compatible with tinea cruris, as well as proximal subungual onychomycoses of toenails, were observed. Read More

    Oral Antifungal Drugs in the Treatment of Dermatomycosis.
    Med Mycol J 2016 ;57(2):J71-5
    Department of Dermatology, Tokyo Women's Medical University.
    Oral antifungal drugs are used primarily to treat tinea unguium; however, they are also useful for other types of tinea. For example, a combination of topical and oral antifungal drugs is effective in hyperkeratotic tinea pedis that is unresponsive to topical monotherapy. In cases of tinea facialis adjacent to the eyes, ears, or mouth, or widespread tinea corporis, or tinea cruris involving the complex skin folds of the external genitalia, it is difficult to apply topical drugs to all the lesions; therefore, oral antifungal drugs are necessary. Read More

    Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review.
    Indian Dermatol Online J 2016 Mar-Apr;7(2):77-86
    Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    The prevalence of superficial mycotic infection worldwide is 20-25% of which dermatophytes are the most common agents. Recent developments in understanding the pathophysiology of dermatophytosis have confirmed the central role of cell-mediated immunity in countering these infections. Hence, a lack of delayed hypersensitivity reaction in presence of a positive immediate hypersensitivity (IH) response to trichophytin antigen points toward the chronicity of disease. Read More

    Male genital dermatophytosis - clinical features and the effects of the misuse of topical steroids and steroid combinations - an alarming problem in India.
    Mycoses 2016 Oct 30;59(10):606-14. Epub 2016 Mar 30.
    Consultant Dermatologist, Anand Polyclinic, Mumbai, India.
    Genital dermatophytosis has been considered rare by most Western authorities. However, to the contrary, Indian reports have shown a higher prevalence of genital dermatophytosis due to warm and humid climate, overcrowding and lack of hygiene. A review is presented for 24 cases of male genital dermatophytosis occurring in patients suffering from tinea cruris in India who have been randomly applying various broad-spectrum steroid antifungal and antibacterial creams containing one or more antifungal and antibiotic in addition to potent corticosteroids, mainly clobetasol propionate. Read More

    Dermatophytic Infections among the Patients Attending Di Skin Hospital and Research Center at Maharajgunj Kathmandu.
    J Nepal Health Res Counc 2015 Sep-Dec;13(31):226-32
    Department of Microbiology, National College, Nayabazar, Kathmandu, Nepal.
    Background: Dermatophytosis is the common and most significant superficial fungal infections because of their widespread involvement among the people all over the world. The clinical presentation, though very typical of ringworm infection, is often confused with other skin disorders, making laboratory diagnosis and confirmation necessary. The aim of this research is to study different clinical variants of dermatophytosis and its associated risk factor among the patients attending Di Skin Hospital and Research Center. Read More

    Epidemiological Aspects of Dermatophytosis in Khuzestan, southwestern Iran, an Update.
    Mycopathologia 2016 Aug 17;181(7-8):547-53. Epub 2016 Feb 17.
    Abadan School of Medical sciences, Abadan, Iran.
    Dermatophytosis is among the most common superficial mycoses in Iran. The purpose of this report was to update the clinical and mycological features of human dermatophytosis in the Khuzestan, southwestern Iran. In the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. Read More

    Epidemiology of Superficial Fungal Infections in Guangdong, Southern China: A Retrospective Study from 2004 to 2014.
    Mycopathologia 2016 Jun 16;181(5-6):387-95. Epub 2016 Feb 16.
    Department of Parasitology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
    Superficial fungal infections are common worldwide; however, the distribution of pathogenic species varies among geographical areas and changes over time. This study aimed to determine the epidemiologic profile of superficial fungal infections during 2004-2014 in Guangzhou, Southern China. Data regarding the superficial mycoses from outpatients and inpatients in our hospital were recorded and analyzed. Read More

    A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections.
    Infect Drug Resist 2016 18;9:1-6. Epub 2016 Jan 18.
    Dermatology, Mediprobe Research Inc., London, ON, Canada.
    Luliconazole is a novel imidazole derivative, which has demonstrated in vitro efficacy against dermatophytes and Candida. The results from Phase III trials show that luliconazole 1% cream applied once daily for 2 weeks successfully resolved the clinical signs and symptoms as well as eradicated the pathologic fungi, which cause tinea pedis. A 1-week treatment with luliconazole 1% cream also produced favorable clinical and mycological results in clinical trials for tinea corporis and tinea cruris. Read More

    Diagnosis directs treatment in fungal infections of the skin.
    Practitioner 2015 Oct;259(1786):25-9, 3
    Dermatophyte fungi are confined to the keratin layer of the epidermis and include three genera: Microsporum, Epidermophyton and Trichophyton. These infections can be transmitted by human contact (anthropophilic), from the soil (geophilic) and by animal (zoophilic) spread. Dermatophyte infections usually present as an erythematous, scaly eruption, which may or may not be itchy. Read More

    Griseofulvin and/or Terbinafine Induced Toxic Epidermal Necrolysis in an Adult Female Patient - A Case Report.
    Curr Drug Saf 2016 ;11(2):192-4
    Department of Pharmacology, Government Medical College and Sir Takhtsinhji General Hospital, Bhavnagar-364001, Gujarat, India.
    An 18 years old female patient, who was taking treatment for tinea cruris developed Toxic Epidermal Necrolysis (TEN) due to therapeutic dose of griseofulvin with concomitant use of terbinafine. Both the drugs were stopped; patient's condition was gradually improved after starting the treatment. As per WHO-UMC causality assessment criteria, association between reaction and drug was possible (for both griseofulvin and terbinafine). Read More

    [2011 Epidemiological Survey of Dermatomycoses in Japan].
    Med Mycol J 2015 ;56(4):J129-35
    Epidemiological Investigation Committee for Human Mycoses in the Japanese Society for Medical Mycology, Chairman and Reporter.
    An epidemiological survey of dermatomycoses and their causative fungus flora in Japan for 2011 was conducted in accordance with methods and criteria of the past four surveys. The survey covered a total number of 36,052 outpatients who visited 12 dermatological clinics throughout Japan. The results were as follows. Read More

    Dermatophytes and other associated fungi in patients attending to some hospitals in Egypt.
    Braz J Microbiol 2015 Jul-Sep;46(3):799-805. Epub 2015 Jul 1.
    Dermatology Department, Faculty of Medicine, Cairo University, Giza, Egypt .
    Dermatophytes are keratinophilic fungi that infect keratinized tissues causing diseases known as dermatophytoses. Dermatophytes are classified in three genera, Epidermophyton, Microsporum, and Trichophyton. This investigation was performed to study the prevalence of dermatomycosis among 640 patients being evaluated at the dermatology clinics at Kasr elainy, El-Husein and Said Galal hospitals in Cairo and Giza between January 2005 and December 2006. Read More

    Molecular Characterization and In Vitro Antifungal Susceptibility of 316 Clinical Isolates of Dermatophytes in Iran.
    Mycopathologia 2016 Feb 14;181(1-2):89-95. Epub 2015 Sep 14.
    Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Km 18 Khazarabad Road, P.O. Box 48175-1665, Sari, Iran.
    Dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. Various species of dermatophytes show significant differences in susceptibility to antifungals. Here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of Iran. Read More

    Dermatophytosis in patients with human immunodeficiency virus infection: clinical aspects and etiologic agents.
    Acta Trop 2015 Oct 19;150:111-5. Epub 2015 Jul 19.
    Division of Virology, Laboratory of Immunopathology Keizo Asami (LIKA), Department of Physiology and Pharmacology, Center of Biological Sciences, Federal University of Pernambuco, Brazil. Electronic address:
    Dermatophytosis in individuals with human immunodeficiency virus infection seems to manifest with atypical, multiple, or extensive lesions more frequently. In addition, there are reports of presentations with little inflammation, called anergics. Less common etiologic agents have been isolated in these individuals, such as Microsporum species. Read More

    Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature.
    J Cutan Med Surg 2015 Mar-Apr;19(2):171-6. Epub 2015 Mar 11.
    SKINNOCENCE: The Skin Clinic & Research Centre, Haryana, IndiaDepartments of Dermatology and STD and Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.
    Background: Tinea indecisiva is characterized by concentric scaly rings simulating tinea imbricata but caused by dermatophytes other than Trichophyton concentricum.

    Objective: Tinea indecisiva has been rarely reported. We report a unique case and review of the previously reported cases, pathogenesis, and management. Read More

    Onychomycosis: epidemiology, diagnosis, and treatment in a changing landscape.
    J Drugs Dermatol 2015 Mar;14(3):223-33
    Onychomycosis is an often overlooked and/or undertreated disease. This may be in part due to an under appreciation among both physicians and patients of its impact on quality of life and the potential for significant complications, from tinea corporis and cruris, to bacterial superinfection. Some health care providers are unaware of the effective low-risk treatments currently available. Read More

    Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India.
    Springerplus 2014 9;3:134. Epub 2014 Mar 9.
    Superannuated as Professor Microbiology, Veterinary Microbiology, Haryana Agricultural University, Hisar, Haryana India.
    Dermatophytes are among the common fungal agents implicated in superficial skin infections worldwide. They include species of Trichophyton, Microsporum and Epidermophyton. In hot and humid climates of tropical and subtropical regions, the incidence of these pathogens is higher. Read More

    Diagnosis and management of tinea infections.
    Am Fam Physician 2014 Nov;90(10):702-10
    University of Iowa Carver College of Medicine, Iowa City, IA, USA.
    Tinea infections are caused by dermatophytes and are classified by the involved site. The most common infections in prepubertal children are tinea corporis and tinea capitis, whereas adolescents and adults are more likely to develop tinea cruris, tinea pedis, and tinea unguium (onychomycosis). The clinical diagnosis can be unreliable because tinea infections have many mimics, which can manifest identical lesions. Read More

    Evidence-based topical treatments for tinea cruris and tinea corporis: a summary of a Cochrane systematic review.
    Br J Dermatol 2015 Mar 9;172(3):616-41. Epub 2015 Feb 9.
    Department of Dermatology, B1-Q, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands.
    Tinea cruris and tinea corporis are common fungal infections. Most can be treated with a variety of topical antifungals. This review aimed to assess the evidence for the effectiveness and safety of topical treatments for tinea cruris and tinea corporis. Read More

    Luliconazole for the treatment of fungal infections: an evidence-based review.
    Core Evid 2014 24;9:113-24. Epub 2014 Sep 24.
    Department of Dermatology, Chacha Nehru Bal Chikitsalaya (Childrens Hospital), Delhi, India.
    Luliconazole is an imidazole antifungal agent with a unique structure, as the imidazole moiety is incorporated into the ketene dithioacetate structure. Luliconazole is the R-enantiomer, and has more potent antifungal activity than lanoconazole, which is a racemic mixture. In this review, we summarize the in vitro data, animal studies, and clinical trial data relating to the use of topical luliconazole. Read More

    Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature.
    J Cutan Med Surg 2014 Oct;18(5):1-6
    Background: Tinea indecisiva is characterized by concentric scaly rings simulating tinea imbricata but caused by dermatophytes other than Trichophyton concentricum.

    Objective: Tinea indecisiva has been rarely reported. We report a unique case and review of the previously reported cases, pathogenesis, and management. Read More

    Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis.
    J Invest Dermatol 2015 Mar 1;135(3):750-8. Epub 2014 Sep 1.
    Department of Dermatology, Jena University Hospital, Jena, Germany.
    Dermatophytes initiate dermatophytosis, but susceptibility to infection is dictated by host genetic factors, although the role of some of these-such as human beta-defensin 2 (hBD-2) genomic (DEFB4) copy number (CN) variation and its induction by IL-22-remains unclear. This was investigated in this cross-sectional study in 442 unrelated Caucasian subjects, including 195 healthy controls and 247 dermatophytosis patients who were divided into five subgroups according to clinical presentation. DNA samples were evaluated for DEFB4 CN variation by relative quantification using the comparative CT method, and serum hBD-2 and IL-22 levels were determined by ELISA. Read More

    Topical antifungal treatments for tinea cruris and tinea corporis.
    Cochrane Database Syst Rev 2014 Aug 4(8):CD009992. Epub 2014 Aug 4.
    Primary Care and Population Sciences, Faculty of Medicine, Aldermoor Health Centre, University of Southampton, Aldermoor Close, Southampton, UK, SO16 5ST.
    Background: Tinea infections are fungal infections of the skin caused by dermatophytes. It is estimated that 10% to 20% of the world population is affected by fungal skin infections. Sites of infection vary according to geographical location, the organism involved, and environmental and cultural differences. Read More

    A clinical and mycological study of dermatophytic infections.
    Indian J Dermatol 2014 May;59(3):262-7
    Department of Dermatology, Father Muller Medical College, Mangalore, Karnataka, India.
    Background: Dermatophytoses refer to superficial fungal infection of keratinized tissues caused by keratinophilic dermatophytes. According to observations worldwide, dermatophytoses are the most common of the superficial fungal infections. It is common in tropics and may present in epidemic proportions in areas with high rates of humidity. Read More

    Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris.
    Indian Dermatol Online J 2014 Apr;5(2):128-31
    Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India.
    Aims: To study and compare the efficacy and safety of topical terbinafine hydrochloride 1% cream and eberconazole nitrate 1% cream in localized tinea corporis and cruris.

    Methods And Materials: Patients were randomized after considering various inclusion and exclusion criteria into two groups. Group A (treated with terbinafine 1% cream for 3 weeks) and group B (treated with eberconazole 1% cream for 3 weeks). Read More

    Prevalence and risk factors for scrotal lesions/anomalies in a cohort of Brazilian men ≥ 40 years of age.
    Sao Paulo Med J 2014 ;132(2):73-9
    Department of Surgery, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
    Objective: To estimate the prevalence of and risk factors for cutaneous lesions of the scrotum and intrascrotal lesions/anomalies among men included in a prostatic cancer screening program in a Brazilian metropolitan city.

    Design And Setting: Cross-sectional study, private outpatient healthcare service.

    Methods: 1731 men aged 40 years or over, participating in a prostate cancer screening program conducted by the municipal public employees' healthcare system, underwent systematic urological assessment by a single examiner. Read More

    A randomized, multicenter, double-blind, vehicle-controlled study evaluating the efficacy and safety of luliconazole cream 1% once daily for 7 days in patients aged ≥ 12 years with tinea cruris.
    J Drugs Dermatol 2014 Jan;13(1):32-8
    Background: Tinea cruris, a pruritic superficial fungal infection of the groin, is the second most common clinical presentation for dermatophytosis.

    Objective: This phase 3 study evaluated the safety and efficacy of topical luliconazole cream 1% in patients with tinea cruris.

    Methods: 483 patients were enrolled and 256 male and female patients aged ≥12 years with clinically evident tinea cruris and eligible for modified intent-to-treat analysis were randomized 2:1 to receive luliconazole cream 1% (n=165) or vehicle (n=91) once daily for 7 days. Read More

    Efficacy and Safety of Terbinafine Hydrochloride 1% Cream vs. Sertaconazole Nitrate 2% Cream in Tinea Corporis and Tinea Cruris: A Comparative Therapeutic Trial.
    Indian J Dermatol 2013 Nov;58(6):457-60
    Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India.
    Context: To the best of our knowledge, till date no study comparing the efficacy and safety of terbinafine hydrochloride 1% cream and sertaconazole nitrate 2% cream has been done in localized tinea corporis and tinea cruris.

    Aims: This clinical trial was carried out to study and compare the efficacy of topical terbinafine hydrochloride 1% cream and sertaconazole nitrate 2% cream in localized tinea corporis and tinea cruris and to know the adverse effects of these antifungal creams.

    Settings And Design: In this prospective, single blind, randomized control trial with two arms, patient were randomized into two groups Group A (treatment with terbinafine cream) and Group B (treatment with sertaconazole cream). Read More

    Detection and relevance of naftifine hydrochloride in the stratum corneum up to four weeks following the last application of naftifine cream and gel, 2%.
    J Drugs Dermatol 2013 Sep;12(9):1004-8
    Background: Two-week treatment using naftifine cream or gel, 2% has been shown to be efficacious in subjects with Tinea pedis and/or Tinea cruris, and in most cases, continued improvement has been observed following cessation of treatment for up to four weeks. One possible explanation for continuous post-treatment improvement is drug-levels remaining in the stratum corneum (SC) as a function of time.

    Objective: The objective is to use tape stripping methodology to assess the amount of drug available in the SC over a 28 day period following the last dose. Read More

    A Molecular Epidemiological Survey of Clinically Important Dermatophytes in Iran Based on Specific RFLP Profiles of Beta-tubulin Gene.
    Iran J Public Health 2013 Sep;42(9):1049-57
    1. Dept. of Medical Parasitology and Mycology, School of Public Health; National Institute of Health Research, Tehran University of Medical Sciences , Tehran, Iran.
    Background: Surveillance of dermatophytosis is essential to determine the likely changes in etiological trends and distribution profile of this infection. In this study beta tubulin gene (BT2), was used as the first time in a PCR-RFLP format to clarify the distribution of dermatophytosis agents in some parts of Iran.

    Methods: A total of 603 clinical isolates was obtained from 500 patients in Tehran, Isfahan, Mazandaran and Guilan provinces. Read More

    Surveillance of dermatophytosis in northeast of Iran (Mashhad) and review of published studies.
    Mycopathologia 2013 Oct 14;176(3-4):247-53. Epub 2013 Aug 14.
    Department of Medical Mycology and Parasitology, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran,
    Dermatophytoses are considered to be one of the major public health problems in the world and are among the most commonly diagnosed skin diseases in Iran. In spite of improved personal hygiene and living environment, dermatophytosis continues to spread and persist. To determine the prevalence of dermatophytosis and their etiologic agents in Mashhad (Iran), five hundred and sixty patients suspected to have fungal infection were studied. Read More

    Comparative assessment of the efficacy and safety of sertaconazole (2%) cream versus terbinafine cream (1%) versus luliconazole (1%) cream in patients with dermatophytoses: a pilot study.
    Indian J Dermatol 2013 Jan;58(1):34-8
    Department of Dermatology, LTMM College and LTMG Hospital, Sion, Mumbai, India.
    Background: Sertaconazole is a new, broad spectrum, fungicidal and fungistatic imidazole with added antipruritic and anti-inflammatory activity that would provide greater symptomatic relief and hence would be beneficial in improving the quality of life for the patient with dermatophytoses.

    Aims And Objectives: To compare efficacy and safety of sertaconazole, terbinafine and luliconazole in patients with dermatophytoses.

    Materials And Methods: 83 patients with tinea corporis and tinea cruris infections were enrolled in this multicentre, randomized, open label parallel study. Read More

    Dermatophytes isolated from superficial fungal infections in Krakow, Poland, between 1995 and 2010.
    Mycoses 2013 Jul 24;56(4):422-8. Epub 2013 Jan 24.
    Department of Pharmaceutical Microbiology, Jagiellonian University Medical College, Kraków, Poland.
    Superficial fungal infections due to dermatophytes are common over the world and their frequency is constantly increasing. The aim of our study was to discuss fungal infections with frequency of occurrence, clinical stages and aetiology in patients admitted to dermatological ward and microbiological laboratory of the specialist hospital in Krakow. Investigations performed between 1995 and 2010 included the group of 5333 individuals. Read More

    Comparison of superficial mycosis treatment using Butenafine and Bifonazole nitrate clinical efficacy.
    Glob J Health Sci 2012 Nov 11;5(1):150-4. Epub 2012 Nov 11.
    Mohammed A Abdul Bari Baghdad Collage of Pharmacy, Bahgdad, Iraq.
    Superficial fungal infections are commonly encountered by the physician. And the continuously changing epidemiology of invasive fungal infections results in the need for an expanded armamentarium of antifungal therapies. This study was designed to evaluate the safety and efficacy of Butenafine (BTF) versus Bifonazole (BFZ) in the treatment of superficial mycosis in a randomized, double-blind, parallel-group trial. Read More

    [2006 Epidemiological survey of dermatomycoses in Japan].
    Med Mycol J 2012 ;53(3):185-92
    Epidemiological Investigation Committee for Human Mycoses in the Japanese Society for Medical Mycology, Japan.
    An epidemiological survey of dermatomycoses and the causative fungus flora of dermatomycoses in Japan for 2006 was made on a total number of 63,029 outpatients who visited 16 dermatological clinics throughout Japan. The results were as follows. 1) Dermatophytosis was the most prevalent cutaneus fungal infection (7,582 cases) seen in these clinics, followed by candidiasis (842 cases) and then Malassezia infections (283 cases). Read More

    1 OF 8