445 results match your criteria Tinea Cruris

Checkerboard analysis to evaluate synergistic combinations of existing antifungal drug and PGMC in isolates from recalcitrant tinea corporis and cruris harboring SQLE gene mutation.

Antimicrob Agents Chemother 2021 Jun 7:AAC0032121. Epub 2021 Jun 7.

Vyome Therapeutics Limited, New Delhi, India.

Recalcitrant dermatophytic infections of the glabrous skin (tinea corporis/cruris/faciei) pose a huge challenge to healthcare systems. Combinations of oral and topical drugs may potentially improve cure rates but the same has never been objectively assessed for this condition in laboratory or clinical studies.The presentstudy was undertaken with an aim of identifying synergistic combinations of oral and topical antifungals by testing clinical isolates obtained from patients with recalcitrant tinea corporis/cruris. Read More

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Prevalence of superficial-cutaneous fungal infections in Shiraz, Iran: A five-year retrospective study (2015-2019).

J Clin Lab Anal 2021 May 24:e23850. Epub 2021 May 24.

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Superficial and cutaneous fungal infections are common in tropical areas. The aim of this study was to provide a basic database of superficial and cutaneous mycoses and the most common etiological agents among patients.

Methods: Between 2015 and 2019, a total of 1807 patients suspected of superficial and cutaneous mycosis referring to the mycology laboratory of Shiraz medical school, Fars, Iran were evaluated. Read More

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Iatrogenic Cushing's Syndrome in Patients with Superficial Dermatophytosis.

Indian Dermatol Online J 2021 Mar-Apr;12(2):237-243. Epub 2021 Mar 2.

Department of Endocrinology and Metabolism University College of Medical Sciences and GTB Hospital (University of Delhi), Delhi, India.

Background: The epidemic-like scenario of superficial fungal infections in India has been complicated by the prescription of systemic and topical potent steroids. As a result, alarming number of patients are presenting with exogenous Cushing's syndrome.

Methods: This cross-sectional study involved 23 patients of superficial dermatophytosis on steroids who presented with clinical features like that of Cushing's syndrome. Read More

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Secondary syphilis mimicking tinea cruris in an HIV infected patient: a case report.

Pan Afr Med J 2021 5;38:133. Epub 2021 Feb 5.

Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

Syphilis is known as the great imitator with various clinical presentations which often lead to confusion and misdiagnosis. A 28-year-old male presented with non-pruritic and painless erythematous patches around the anus and scrotum. Initial differential diagnosis with tinea cruris. Read More

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The unprecedented epidemic-like scenario of dermatophytosis in India: I. Epidemiology, risk factors and clinical features.

Indian J Dermatol Venereol Leprol 2021 Mar-Apr;87(2):154-175

Bhojani Clinic, Mumbai, Maharashtra, India.

Dermatophytosis has attained unprecedented dimensions in recent years in India. Its clinical presentation is now multifarious, often with atypical morphology, severe forms and unusually extensive disease in all age groups. We hesitate to call it an epidemic owing to the lack of population-based prevalence surveys. Read More

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Epidemiological study of terbinafine-resistant dermatophytes isolated from Japanese patients.

J Dermatol 2021 Apr 13;48(4):564-567. Epub 2021 Jan 13.

Department of Veterinary Dermatology, Nihon University College of Bioresource Sciences, Fujisawa, Kanagawa, Japan.

Terbinafine (TRF) has been used in the treatment of fungal infections for more than 20 years. Recently, TRF-resistant Trichophyton interdigitale and T. rubrum strains have been isolated from human patients worldwide. Read More

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Terbinafine resistance in dermatophytes: Time to revisit alternate antifungal therapy.

J Mycol Med 2021 Mar 19;31(1):101087. Epub 2020 Nov 19.

Department of Microbiology, University College of Medical Sciences, Delhi 110095, India. Electronic address:

Resistant superficial dermatophytic infections of the skin and its appendages have emerged as a major health problem in India. Mutations in Squalene epoxidase gene have led to increasing incidence of resistance to terbinafine in dermatophytic isolates. We examined six patients with recalcitrant dermatophytosis attending Dermatology OPD at a tertiary care hospital and demonstrated terbinafine resistance by molecular method. Read More

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Topical clotrimazole cream for the treatment of tinea cruris: A retrospective study.

Medicine (Baltimore) 2020 Nov;99(47):e23189

Department of Dermatology.

This retrospective study assessed the efficacy and safety of 1% topical clotrimazole cream for the treatment of patients with tinea cruris (TC).We included 86 patients with confirmed TC for the presence of fungal hyphae. Of those, 43 patients received 1% topical clotrimazole cream for a total of 4 consecutive weeks, and were assigned to an experimental group. Read More

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November 2020

Analysis on the pathogenic fungi in patients with superficial mycosis in the Northeastern China during 10 years.

Exp Ther Med 2020 Dec 27;20(6):281. Epub 2020 Oct 27.

Department of Dermatology, The First Affiliated Hospital of Qiqihar Medical University, Qiqihar, Heilongjiang 161041, P.R. China.

This study analyzed the infection of superficial mycosis and the relationship between the distribution characteristics of pathogenic fungi and age, time and sex in Northeast China in the past 10 years. We would like to provide a theoretical basis for the diagnosis and treatment of related diseases. From December 2008 to December 2018, 5,374 superficial mycoses from Northeast China were selected. Read More

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December 2020

Dermatophytosis caused by Nannizzia nana.

J Mycol Med 2021 Jun 6;31(2):101047. Epub 2020 Oct 6.

Psychodermatology task force of the Ibero-Latin American College of Dermatology (CILAD), Buenos Aires, Argentina; European Women's Dermatologic and Venereologic Society (EWDVS), Tui, Spain; Efficiency, Quality, and Costs in Health Services Research Group (EFISALUD), Health Research Institute, SERGAS-UVIGO, Vigo, Spain; Dermatology Department, Hospital do Meixoeiro and University of Vigo, 36200 Vigo, Spain. Electronic address:

Purpose: In this paper, we reported three distinct cases of tinea, including tenia ungulum, tenia pedis, and tenia cruris caused by the infection of Nannizzia nana in the immunocompetent patients who were also the residents of Guatemala. Dermatophytes were identified phenotypically and genotypically. Thereafter, DNA was extracted from the fungal isolates and a fragment of the ITS1-5. Read More

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A rare case of coexistence of autoimmune polyglandular syndrome type 3 with growth hormone deficiency and hyperthyroidism in a patient with pseudo-Turner's syndrome.

J Int Med Res 2020 Oct;48(10):300060520961684

Department of Emergency, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Autoimmune polyglandular syndrome (APS) is a rare disease that is characterized by autoimmune reactions to multiple endocrine and non-endocrine organs, which can be divided into four main types. The principal manifestations of APS-3 are autoimmune thyroid disease and other autoimmune diseases, such as type 1 diabetes, atrophic gastritis, pernicious anemia, vitiligo, alopecia, and myasthenia gravis, but not Addison's disease or hypoparathyroidism. Here we report a case demonstrating the rare coexistence of growth hormone deficiency and hyperthyroidism with sexual dysgenesis, secondary amenorrhea, cardiomegaly, splenomegaly, hypoproteinemia, pleural effusion, seroperitoneum, pericardial effusion, anasarca, osteoporosis, vitamin D deficiency, iron-deficiency anemia, poor blood coagulation, leucocytopenia, peripheral neuropathy, hyperuricemia, ichthyosis, tinea cruris, and onychomycosis. Read More

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October 2020

Terbinafine-induced lichenoid drug eruption: case report and review of terbinafine-associated cutaneous adverse events.

Dermatol Online J 2020 Jul 15;26(7). Epub 2020 Jul 15.

San Diego Family Dermatology, National City, CA, Touro University California College of Osteopathic Medicine, Vallejo, CA Scripps Family Medicine Residency, Scripps Mercy Hospital Chula Vista, Chula Vista, CA Family Medicine Residency, Family Health Centers of San Diego, San Diego, CA.

Terbinafine is an antifungal agent used in the treatment of hair, nail, and skin dermatophyte infections. Skin side effects to terbinafine are not common. Lichenoid drug eruption is a medication-related adverse cutaneous event; the lesion morphology and pathology mimic lichen planus. Read More

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Skin Barrier Function Defect - A Marker of Recalcitrant Tinea Infections.

Indian Dermatol Online J 2020 Jul-Aug;11(4):566-569. Epub 2020 Jul 13.

Department of Dermatology, Sawai Mansingh Medical College, Jaipur, Rajasthan, India.

Context: Recently, there has been an increase in the number of chronic, recurrent, and recalcitrant dermatophytosis. Many factors implicated are barrier defects, aberrant host immune response, application of steroids or other irrational combination creams, transmission within family, occlusive clothing, poor hygienic conditions, poor compliance, drug resistance and virulence of the infecting strain. Transepidermal water loss (TEWL) is an important index in accessing the barrier function of skin. Read More

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Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) Task Force against Recalcitrant Tinea (ITART) Consensus on the Management of Glabrous Tinea (INTACT).

Indian Dermatol Online J 2020 Jul-Aug;11(4):502-519. Epub 2020 Jul 13.

Consultant Dermatologist, Dr. Kaushal's Skin Clinic, Agra, Uttar Pradesh, India.

Background And Aims: Dermatophytosis has always been a common superficial mycosis in India. However, the past 6-7 years have seen an unprecedented increase in the number of patients affected by recurrent, chronic, recalcitrant and steroid modified dermatophytosis involving the glabrous skin (tinea corporis, tinea cruris and tinea faciei). Importantly, there has been a notable decrease in clinical responsiveness to commonly used antifungals given in conventional doses and durations resulting in difficult-to-treat infections. Read More

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A curious observation of passive transfer of steroid antifungal combination creams to the scrotum in patients of tinea cruris-Is this forme fruste of red scrotum syndrome?

Dermatol Ther 2020 11 7;33(6):e14212. Epub 2020 Sep 7.

Department of Dermatology, KPC Medical college and Hospital, Kolkata, West Bengal, India.

We report 16 patients of tinea cruris who presented with an asymptomatic red scrotum due to fixed dose combination creams containing antifungal agents and topical steroids applied to the thighs as a treatment of tinea cruris. The erythema resolved upon starting appropriate treatment with single molecule antifungal creams and oral antifungal drugs in about six weeks' time in majority of cases. We propose that this clinical presentation may be akin to red scrotum syndrome (RSS). Read More

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November 2020

Psychosocial and Financial Impact of Disease among Patients of Dermatophytosis, a Questionnaire-Based Observational Study.

Indian Dermatol Online J 2020 May-Jun;11(3):373-377. Epub 2020 May 10.

Department of Dermatology, Venereology and Leprosy, Gujarat Cancer Society Medical College, Hospital and Research Centre, Ahmedabad, Gujarat, India.

Introduction: In the present epidemic of chronic, recalcitrant, and widespread dermatophytosis, impact of disease on quality of life (QoL) can be severe. Similarly, financial impact due to treatment cost and loss of wages needs consideration too.

Aims And Objectives: Our primary aim was to evaluate the impact of dermatophytosis on QoL and the financial burden on individual and family. Read More

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Limited effectiveness of four oral antifungal drugs (fluconazole, griseofulvin, itraconazole and terbinafine) in the current epidemic of altered dermatophytosis in India: results of a randomized pragmatic trial.

Br J Dermatol 2020 11 15;183(5):840-846. Epub 2020 Jun 15.

Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Background: Dermatophytic infections have undergone unprecedented changes in India in the recent past. Clinical trials to find out the effectiveness of the four main oral antifungal drugs are lacking.

Objectives: We tested the effectiveness of oral fluconazole, griseofulvin, itraconazole and terbinafine in chronic and chronic relapsing tinea corporis, tinea cruris and tinea faciei in an investigator-initiated, randomized, pragmatic trial. Read More

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November 2020

A prospective study on patterns of topical steroids self-use in dermatophytoses and determinants predictive of cutaneous side effects.

Dermatol Ther 2020 07 23;33(4):e13633. Epub 2020 Jun 23.

Department of Pharmacology, Dr Ram Manohar Lohia Hospital and PGIMER, New Delhi, India.

Nonprescription use of topical corticosteroids (TCS) is a significant concern. This can lead to cutaneous adverse effects, altered morphology of skin disorders and chronicity of cutaneous infections. To record and analyze the patterns of TCS use in patients with tinea corporis/cruris and analyze factors determining the development of cutaneous side effects. Read More

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Photodynamic therapy treatment of superficial fungal infections: A systematic review.

Photodiagnosis Photodyn Ther 2020 Sep 25;31:101774. Epub 2020 Apr 25.

Department of Dermatology, Zealand University Hospital, Sygehusvej 5, DK-4000, Roskilde, Denmark; Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, DK-2200, Copenhagen, Denmark; Unit of Mycology, Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Artillerivej 5, DK-2300, Copenhagen, Denmark. Electronic address:

Background: Fungal infections in skin, hair and nails affect up to 25 % of the global population. Conventional antifungal treatment is effective but due to resistance, treatment failure, drug interactions, and treatment related toxicity, there is a need for alternative treatments. Photodynamic therapy (PDT) has shown antimicrobial properties and is used increasingly for fungal infections. Read More

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September 2020

Epidemiological survey of 42 403 dermatophytosis cases examined at Nagasaki University Hospital from 1966 to 2015.

J Dermatol 2020 Jun 15;47(6):615-621. Epub 2020 Apr 15.

Nagasaki Ekisaikai Hospital, Nagasaki, Japan.

The causative species of a total of 42 403 dermatophytosis cases that occurred during 1966-2015 were surveyed. The most prevalent clinical type was tinea pedis, followed by tinea unguium, corporis, cruris, manus, faciei and capitis. The prevalence of tinea faciei and capitis has increased since the late 1990s and the late 2000s, respectively. Read More

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Clinicomycological Study of Dermatophytosis in a Tertiary Care Hospital in Eastern India: A Cross-sectional Study.

Indian Dermatol Online J 2020 Jan-Feb;11(1):46-50. Epub 2019 Sep 26.

Department of Dermatology, IMS and SUM Hospital, K8 Kalinga Nagar, Shampur, Bhubaneswar, Odisha, India.

Introduction: Dermatophytosis is a fungal infection of the skin, hair, and nails. In the past several years, it has emerged as a general public health problem in our country. Studies from different regions reveal varying patterns of etiological distribution of the disease. Read More

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September 2019

Skin Infections and Outpatient Burn Management: Fungal and Viral Skin Infections.

FP Essent 2020 Feb;489:16-20

Maine-Dartmouth Family Medicine Residency, 15 East Chestnut St, Augusta, ME 04330.

Fungal and viral skin infections are common and typically are managed by family physicians. The fungal skin infections commonly seen in family practice include the various forms of tinea: tinea corporis, tinea gladiatorum, tinea cruris, tinea pedis, tinea capitis, and tinea unguium (eg, onychomycosis). Common viral skin infections include herpes simplex virus infection, herpes zoster, cutaneous and genital warts, and molluscum contagiosum. Read More

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February 2020

Primary extramammary Paget's disease: a clinicopathological study of 28 cases.

Int J Clin Exp Pathol 2019 1;12(9):3426-3432. Epub 2019 Sep 1.

Department of Surgical Oncology, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui, P. R. China.

To analyze the clinical and histopathological manifestations, immunohistochemistry, treatment, and prognostic factors of primary, extramammary Paget's disease (EMPD), we systematically reviewed the clinical presentations, histopathology and follow-up courses of 28 patients with primary EMPD. Clinically, their symptoms and morphology mimicked various types of dermatoses, such as seborrheic dermatitis, eczema, candidiasis, tinea cruris and erythrasma, so the initial diagnosis of EMPD was often delayed or missed. Histopathology showed invasive EMPD, and the tumor cells were mostly solid nests or had a glandular structure. Read More

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September 2019

Dermoscopy - a simple and rapid in vivo diagnostic technique for tinea incognito.

An Bras Dermatol 2019 Sep - Oct;94(5):612-614. Epub 2019 Sep 30.

Department of Dermatology & STD, Patna Medical College & Hospital, Patna, India.

Tinea incognito resulting from corticosteroid abuse is becoming very common in the tropics. Its diagnosis is tricky owing to its confusing morphology, as well as practical and technical issues associated with mycological tests. Dermoscopy has now evolved as a novel diagnostic tool for diagnosing tinea incognito in such challenging situations, since the typical hair changes such as Morse-code hairs, deformable hairs, translucent hairs, comma and cork screw hairs, and perifollicular scaling may be seen despite steroid use, irrespective of mycological results. Read More

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December 2019

Can Dermoscopy Serve as a Diagnostic Tool in Dermatophytosis? A Pilot Study.

Indian Dermatol Online J 2019 Sep-Oct;10(5):530-535. Epub 2019 Aug 28.

Department of Dermatology, STD and Leprosy, Government Medical College, Srinagar, University of Kashmir, Jammu and Kashmir, India.

Background: Dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders.

Aim: The purpose of the study was to describe the dermoscopic findings in various dermatophytosis.

Materials And Methods: This cross-sectional study included 100 clinically diagnosed tinea infections of skin, hair, and nails, which were evaluated using a dermoscope (Dermlite 3 gen DL3N, California USA, 10x). Read More

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A Cross-Sectional Study on the Dermatoses in Postmenopausal Patients at a Rural-Based Tertiary Health Care Center.

Indian J Dermatol 2019 Sep-Oct;64(5):360-365

Department of Dermatology and Venereology, Pramukhswami Medical College, Karamsad, Gujarat, India.

Context: There is still a dearth of knowledge regarding the types of dermatoses occurring in postmenopausal women. The common disorders occurring in postmenopausal women and the probable effects of hormonal fluctuations on the skin have to be considered while treating postmenopausal women.

Aims: To study clinical patterns of dermatosis in menopausal women. Read More

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September 2019

A unique multidrug-resistant clonal Trichophyton population distinct from Trichophyton mentagrophytes/Trichophyton interdigitale complex causing an ongoing alarming dermatophytosis outbreak in India: Genomic insights and resistance profile.

Fungal Genet Biol 2019 12 3;133:103266. Epub 2019 Sep 3.

Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India. Electronic address:

There has been a considerable upsurge of extensive, treatment recalcitrant, dermatophytosis presenting as tinea corporis and tinea cruris in India since the past few years. Genome analysis of Trichophytonspecies causing severe superficial dermatophytosis in North India confirmed a unique clade related to the T.mentagrophytes/interdigitale complex, seeming to belong to an early diverging clade of the complex. Read More

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December 2019

2016 Epidemiological Survey of Dermatomycoses in Japan.

Med Mycol J 2019 ;60(3):75-82

Department of Dermatology, Teikyo University Mizonokuchi Hospital.

We report here the results of the 2016 epidemiological survey of dermatomycosis in Japan. In total, 6,776 cases were analyzed as follows: dermatophytosis, 5,772 cases (85.2%); candidiasis, 757 cases (11. Read More

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February 2020

Trichophyton mentagrophytes and T interdigitale genotypes are associated with particular geographic areas and clinical manifestations.

Mycoses 2019 Nov 9;62(11):1084-1091. Epub 2019 Sep 9.

Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

The fungi Trichophyton mentagrophytes and T interdigitale account for significant amount of dermatophytosis cases worldwide. These two dermatophytes form a species complex and have a number of ribosomal internal transcribed spacer (ITS) region genotypes, allowing simultaneous species identification and strain typing. Our aim was to describe the geographic distribution of T mentagrophytes/T interdigitale ITS region genotypes and find an association between the genotypes and clinical presentations of respective infections. Read More

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November 2019