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    Is Antifungal Resistance a Cause for Treatment Failure in Dermatophytosis: A Study Focused on Tinea Corporis and Cruris from a Tertiary Centre?
    Indian Dermatol Online J 2018 Mar-Apr;9(2):90-95
    Department of Dermatology, Maulana Azad Medical College, New Delhi, India.
    Background: Dermatophytoses are one of the most common skin diseases that have been largely simple to treat. However, in recent years, these infections have become recalcitrant to treatment which can possibly be due to antifungal resistance.

    Aim: To analyze the resistance pattern of patients with recalcitrant dermatophytoses. Read More

    Epidemiology of dermatophytoses in 31 municipalities of the province of Buenos Aires, Argentina: A 6-year study.
    Rev Iberoam Micol 2018 Mar 29. Epub 2018 Mar 29.
    Mycology Department, INEI, ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires, Argentina.
    Background: No reliable data are available in the province of Buenos Aires regarding the frequency of dermatophytoses and other fungal diseases. The distribution of the clinical forms and the species involved are also unknown.

    Aims: To present the data collected by the laboratories participating in the Mycology Network of the province of Buenos Aires (MNPBA) from a retrospective epidemiological survey on dermatophytoses. Read More

    High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the Squalene epoxidase (SQLE) gene.
    Mycoses 2018 Mar 25. Epub 2018 Mar 25.
    Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
    In the last few years infections caused by dermatophytes along with a concomitant increase in the number of difficult to treat cases has increasingly been recognized indicating that dermatophytosis remains a challenging public health problem. The majority of infections are caused by Trichophyton rubrum and T. mentagrophytes complex. Read More

    Novel in vivo observations of scrotal Nannizzia gypsea infection.
    Br J Dermatol 2018 Feb 25. Epub 2018 Feb 25.
    Department of Dermatology, Affiliated Third Hospital of Hangzhou, Anhui Medical University.
    Tinea cruris is a common dermatophytosis, which usually firstly involved the intertriginous fold near the scrotum. Although dermatophytes may colonize the scrotum, they typically do not infect scrotal skin. However, tinea of scrotum is seldom reported as a specific type of Microsporum gypseum infection, presenting as white-paint-dot appearance, scutular-like or pseudomembranous-like lesions in immunocompromised or immunocompetent patients . Read More

    Current Trends of Using Systemic Antifungal Drugs and their Comparative Efficacy in Tinea Corporis and Tinea Cruris in Outpatient Department of Dermatology in a Tertiary Level Hospital.
    Mymensingh Med J 2018 Jan;27(1):52-56
    Dr Taslima Sultana, M. Phil (Thesis Part), Department of Pharmacology & Therapeutics, Mymensingh Medical College (MMC), Mymensingh, Bangladesh.
    Tinea corporis & cruris are one of the earliest known fungal infection and are very common throughout the world. Although tinea corporis and tinea cruris does not cause mortality but causes morbidity and poses a major health problem. This study was conducted to evaluate the Comparative Efficacy of Terbinafine and Fluconazole in the Treatment of Tinea corporis and Tinea cruris. Read More

    Characterizing the clinical isolates of dermatophytes in Hamadan city, Central west of Iran, using PCR-RLFP method.
    J Mycol Med 2018 Mar 11;28(1):101-105. Epub 2018 Feb 11.
    Infectious Diseases Research Center (IDRC), Department of Medical Parasitology and Mycology, Arak University of Medical Sciences, Arak, Iran. Electronic address:
    Objective: Dermatophytosis is one of the most common mycotic infections, which considered as a public health problem in the major of countries. This study evaluated the molecular epidemiology of dermatophytosis in patients referred to Farshchian hospital in Hamadan city with PCR-RFLP method.

    Materials And Methods: Four hundred and five specimens from clinically suspected patients of dermatophytosis were collected and analyzed by direct microscopic and culture. Read More

    A Comparative Study of Polymerase Chain Reaction-Restriction Fragment Length Polymorphism and Fungal Culture for the Evaluation of Fungal Species in Patients with .
    Open Access Maced J Med Sci 2017 Dec 21;5(7):844-847. Epub 2017 Nov 21.
    Universitas Sumatera Utara, Fakultas Kedokteran, Dermatology and Venereology, Medan, Indonesia.
    Background: Tinea cruris is the second most common dermatophytosis in the world and the most common in Indonesia. The conventional laboratory tests for dermatophyte infection are slow and less specific. Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) is a PCR method with the addition of enzyme after amplification, therefore enabling for more specific results. Read More

    Epidemiological status of dermatophytosis in Guilan, north of Iran.
    Curr Med Mycol 2017 Mar;3(1):20-24
    Division of Molecular Biology, Department of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background And Purpose: The epidemiological features of dermatophytoses have been characterized in many geographical locations of Iran, but not in Guilan, North of Iran. This study was carried out to determine the distribution pattern of dermatophytoses and their relevant agents in Guilan, North of Iran, over a period of one year, from April 2010 to April 2011.

    Materials And Methods: The clinical samples of skin, hair, and nail from 889 outpatients (317 men vs. Read More

    Management of mycoses in daily practice.
    G Ital Dermatol Venereol 2017 Dec;152(6):642-650
    Department of Pathophysiology and Transplantation, Università degli Studi di Milano, IRCCS Foundation, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy -
    The guideline recommendations, albeit founded on thorough reviews of clinically relevant literature data, are often not immediately adaptable to everyday life. Considering the marked heterogeneity of superficial mycoses, each of them requires specific management in a real life context; in all cases diagnostic confirmation is required with microscopic and culture examination. In tinea capitis oral therapy is necessary (minimum six weeks) and should be continued until clinical and, above all, mycological healing. Read More

    Analysis on curative effects and safety of 2% liranaftate ointment in treating tinea pedis and tinea corporis & cruris.
    Pak J Pharm Sci 2017 May;30(3(Special)):1103-1106
    Xinjiang Medical University, Wulumuqi, China.
    The paper is intended to analyze and evaluate the specific curative effect and safety of 2% liranaftate ointment in treating patients with tinea pedis and tinea cruris. 1,100 cases of patients with tinea pedis and tinea corporis & cruris were selected as research objects and were divided into two groups according to the random number table method. They were treated with different methods: 550 cases of patients were treated with 2% liranaftate ointment for external use in the observation group and the rest 550 cases of patients were treated with 1% bifonazole cream in the control group. Read More

    Clinico-mycological study of dermatophytic infections and their sensitivity to antifungal drugs in a tertiary care center.
    Indian J Dermatol Venereol Leprol 2017 Jul-Aug;83(4):436-440
    Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
    Background: Worldwide, dermatophytic infections are running a chronic course either due to ineffective treatment or emerging drug resistance. In the past three decades, there has been an increase in incidence and non-responsiveness to conventional antifungals, which suggests that there is a need of antifungal sensitivity testing.

    Aims: This study was aimed at identifying clinico-mycological pattern of dermatophytic infections in patients attending thedermatology outpatient department of a tertiary care hospital, and to obtain the sensitivity pattern of isolates against six commonly used oral antifungals (fluconazole, terbinafine, itraconazole, ketoconazole, griseofulvin and voriconazole). Read More

    Incidence and biodiversity of yeasts, dermatophytes and non-dermatophytes in superficial skin infections in Assiut, Egypt.
    J Mycol Med 2017 Jun 7;27(2):166-179. Epub 2017 Feb 7.
    Department of Botany and Microbiology, Faculty of Science, Assiut University Mycological Centre, Assiut University, Assiut, Egypt.
    Objective: The aim was to identify the incidence of the causal agents from dermatophytes, non-dermatophytes and yeasts in Assiut Governorate employing, beside the morphological and physiological techniques, the genotypic ones.

    Patients: Samples from infected nails, skin and hair were taken from 125 patients.

    Materials And Methods: Patients who presented with onychomycosis, tinea capitis, tinea corporis, tinea cruris and tinea pedis during the period from February 2012 to October 2015 were clinically examined and diagnosed by dermatologists and were guided to Assiut University Mycological Centre for direct microscopic examination, culturing and identification. Read More

    Computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes.
    Bioinformation 2016 15;12(3):197-201. Epub 2016 Jun 15.
    Biotechnology Branch, University Institute of Engineering and Technology (U.I.E.T), Punjab University, Chandigarh 160014, India.
    Dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. The infection known as dermatophytosis, caused by members of the genera Microsporum, Trichophyton, and Epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea corporis), nail (tinea unguium), and hand (tinea manuum). The identification of evolutionary relationship between these three genera of dermatophyte is epidemiologically important to understand their pathogenicity. Read More

    Efficacy and tolerability of topical sertaconazole versus topical terbinafine in localized dermatophytosis: A randomized, observer-blind, parallel group study.
    Indian J Pharmacol 2016 Nov-Dec;48(6):659-664
    Department of Pharmacology, Venerology and Leprosy, R. G. Kar Medical College and Hospital, Kolkata, West Bengal, India.
    Objective: Epidermal dermatophyte infections most commonly manifest as tinea corporis or tinea cruris. Topical azole antifungals are commonly used in their treatment but literature suggests that most require twice-daily application and provide lower cure rates than the allylamine antifungal terbinafine. We conducted a head-to-head comparison of the effectiveness of the once-daily topical azole, sertaconazole, with terbinafine in these infections. Read More

    Epidemiology of Dermatophytoses in Crete, Greece.
    Med Mycol J 2016 ;57(4):E69-E75
    Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine.
    Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. Read More

    Risk-Factors and Awareness of HPV in Turkish people with Anogenital Warts in Bagcilar district: a Cross-Sectional Study.
    Arch Iran Med 2016 Oct;19(10):715-719
    Erciyes University Faculty of Medicine, Department of Public Health, Kayseri, Turkey.
    Background: Anogenital warts (AGWs) are epithelial tumors which develop as a result of human papilloma virus (HPV) infection. We aimed to assess the sociodemographic, sexual and other possible risk-factors, and awareness of the HPV infection among Turkish people with AGW in the Bagcilar district of Istanbul.

    Methods: A cross-sectional study was conducted on 273 patients (183 men, 90 women) with AGW between October 2014 - March 2015. Read More

    Relapse after Oral Terbinafine Therapy in Dermatophytosis: A Clinical and Mycological Study.
    Indian J Dermatol 2016 Sep-Oct;61(5):529-33
    Department of Microbiology, Government Medical College, Srinagar, Jammu and Kashmir, India.
    Background: The incidence of recurrent tinea infections after oral terbinafine therapy is on the rise.

    Aim: This study aims to identify the appearance of incomplete cure and relapse after 2-week oral terbinafine therapy in tinea corporis and/or tinea cruris.

    Materials And Methods: A total of 100 consecutive patients clinically and mycologically diagnosed to have tinea corporis and/or tinea cruris were included in the study. Read More

    Epidemiological trends of dermatophytosis in Tehran, Iran: A five-year retrospective study.
    J Mycol Med 2016 Dec 9;26(4):351-358. Epub 2016 Aug 9.
    Department of Medical Mycology, Pasteur Institute of Iran, Tehran 13164, Iran. Electronic address:
    Objective: Dermatophytosis is the most frequent fungal infection all over the world and its frequency is constantly increasing. The aim of this study was to evaluate clinical features and epidemiological trends of dermatophytosis over the years 2010 to 2014 in Tehran, Iran.

    Patients And Methods: A total of 13,312 patients clinically suspected of cutaneous fungal infections were examined. Read More

    Isolation, Identification, and In Vitro Antifungal Susceptibility Testing of Dermatophytes from Clinical Samples at Sohag University Hospital in Egypt.
    Electron Physician 2016 Jun 25;8(6):2557-67. Epub 2016 Jun 25.
    Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Egypt.
    Aim: The objective of this study was to isolate, identify, and explore the in-vitro antifungal susceptibility pattern of dermatophytes isolated from clinically suspected cases of dermatophytosis (tinea infections) attending the Dermatology Outpatient Clinic.

    Methods: This study was conducted at Sohag University Hospital from December 2014 to December 2015. Clinical samples (e. Read More

    New Antifungal Agents and New Formulations Against Dermatophytes.
    Mycopathologia 2017 Feb 8;182(1-2):127-141. Epub 2016 Aug 8.
    Mediprobe Research Inc., 645 Windermere Road, London, ON, Canada.
    A variety of oral and topical antifungal agents are available for the treatment of superficial fungal infections caused by dermatophytes. This review builds on the antifungal therapy update published in this journal for the first special issue on Dermatophytosis (Gupta and Cooper 2008;166:353-67). Since 2008, there have not been additions to the oral antifungal armamentarium, with terbinafine, itraconazole, and fluconazole still in widespread use, albeit for generally more severe or recalcitrant infections. Read More

    Characterization of clinically important dermatophytes in North of Iran using PCR-RFLP on ITS region.
    J Mycol Med 2016 Dec 3;26(4):345-350. Epub 2016 Aug 3.
    Department of Biotechnology and Molecular Medicine, Arak University of Medical Sciences, Arak, Iran.
    Objective: Dermatophytosis is considered as one of the major public health problems in the world. Accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. In this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. Read More

    Tavaborole, Efinaconazole, and Luliconazole: Three New Antimycotic Agents for the Treatment of Dermatophytic Fungi.
    J Pharm Pract 2017 Dec 3;30(6):621-630. Epub 2016 Aug 3.
    1 College of Pharmacy, Ferris State University, Big Rapids, MI, USA.
    Fungal diseases of the nail bed (onychomycosis) and epidermis are recurrent illnesses in the elderly and immunocompromised patients, which have few efficacious treatment options. Current treatment options for onychomycosis are limited to topical agents, laser treatment, and oral antifungals. Previous generations of topical agents were not efficacious, owing to poor penetration of the nail bed. Read More

    [Clinical problems in medical mycology: Problem number 50].
    Rev Iberoam Micol 2017 Jan - Mar;34(1):53-55. Epub 2016 Jul 19.
    Unidad Micología, Hospital de Infecciosas Francisco Javier Muñiz, Buenos Aires, Argentina. Electronic address:
    We present the case of a 34 year-old man, HIV-positive, who had suffered a disseminated histoplasmosis treated with amphotericin B one year before his admission. He was admitted at the Infectious Diseases Muñiz Hospital with a non-lithiasic chlolecystitis. During the clinical examination perigenital skin lesions compatible with tinea cruris, as well as proximal subungual onychomycoses of toenails, were observed. Read More

    Oral Antifungal Drugs in the Treatment of Dermatomycosis.
    Med Mycol J 2016 ;57(2):J71-5
    Department of Dermatology, Tokyo Women's Medical University.
    Oral antifungal drugs are used primarily to treat tinea unguium; however, they are also useful for other types of tinea. For example, a combination of topical and oral antifungal drugs is effective in hyperkeratotic tinea pedis that is unresponsive to topical monotherapy. In cases of tinea facialis adjacent to the eyes, ears, or mouth, or widespread tinea corporis, or tinea cruris involving the complex skin folds of the external genitalia, it is difficult to apply topical drugs to all the lesions; therefore, oral antifungal drugs are necessary. Read More

    Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review.
    Indian Dermatol Online J 2016 Mar-Apr;7(2):77-86
    Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    The prevalence of superficial mycotic infection worldwide is 20-25% of which dermatophytes are the most common agents. Recent developments in understanding the pathophysiology of dermatophytosis have confirmed the central role of cell-mediated immunity in countering these infections. Hence, a lack of delayed hypersensitivity reaction in presence of a positive immediate hypersensitivity (IH) response to trichophytin antigen points toward the chronicity of disease. Read More

    Male genital dermatophytosis - clinical features and the effects of the misuse of topical steroids and steroid combinations - an alarming problem in India.
    Mycoses 2016 Oct 30;59(10):606-14. Epub 2016 Mar 30.
    Consultant Dermatologist, Anand Polyclinic, Mumbai, India.
    Genital dermatophytosis has been considered rare by most Western authorities. However, to the contrary, Indian reports have shown a higher prevalence of genital dermatophytosis due to warm and humid climate, overcrowding and lack of hygiene. A review is presented for 24 cases of male genital dermatophytosis occurring in patients suffering from tinea cruris in India who have been randomly applying various broad-spectrum steroid antifungal and antibacterial creams containing one or more antifungal and antibiotic in addition to potent corticosteroids, mainly clobetasol propionate. Read More

    Dermatophytic Infections among the Patients Attending Di Skin Hospital and Research Center at Maharajgunj Kathmandu.
    J Nepal Health Res Counc 2015 Sep-Dec;13(31):226-32
    Department of Microbiology, National College, Nayabazar, Kathmandu, Nepal.
    Background: Dermatophytosis is the common and most significant superficial fungal infections because of their widespread involvement among the people all over the world. The clinical presentation, though very typical of ringworm infection, is often confused with other skin disorders, making laboratory diagnosis and confirmation necessary. The aim of this research is to study different clinical variants of dermatophytosis and its associated risk factor among the patients attending Di Skin Hospital and Research Center. Read More

    Epidemiological Aspects of Dermatophytosis in Khuzestan, southwestern Iran, an Update.
    Mycopathologia 2016 Aug 17;181(7-8):547-53. Epub 2016 Feb 17.
    Abadan School of Medical sciences, Abadan, Iran.
    Dermatophytosis is among the most common superficial mycoses in Iran. The purpose of this report was to update the clinical and mycological features of human dermatophytosis in the Khuzestan, southwestern Iran. In the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. Read More

    Epidemiology of Superficial Fungal Infections in Guangdong, Southern China: A Retrospective Study from 2004 to 2014.
    Mycopathologia 2016 Jun 16;181(5-6):387-95. Epub 2016 Feb 16.
    Department of Parasitology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
    Superficial fungal infections are common worldwide; however, the distribution of pathogenic species varies among geographical areas and changes over time. This study aimed to determine the epidemiologic profile of superficial fungal infections during 2004-2014 in Guangzhou, Southern China. Data regarding the superficial mycoses from outpatients and inpatients in our hospital were recorded and analyzed. Read More

    A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections.
    Infect Drug Resist 2016 18;9:1-6. Epub 2016 Jan 18.
    Dermatology, Mediprobe Research Inc., London, ON, Canada.
    Luliconazole is a novel imidazole derivative, which has demonstrated in vitro efficacy against dermatophytes and Candida. The results from Phase III trials show that luliconazole 1% cream applied once daily for 2 weeks successfully resolved the clinical signs and symptoms as well as eradicated the pathologic fungi, which cause tinea pedis. A 1-week treatment with luliconazole 1% cream also produced favorable clinical and mycological results in clinical trials for tinea corporis and tinea cruris. Read More

    Diagnosis directs treatment in fungal infections of the skin.
    Practitioner 2015 Oct;259(1786):25-9, 3
    Dermatophyte fungi are confined to the keratin layer of the epidermis and include three genera: Microsporum, Epidermophyton and Trichophyton. These infections can be transmitted by human contact (anthropophilic), from the soil (geophilic) and by animal (zoophilic) spread. Dermatophyte infections usually present as an erythematous, scaly eruption, which may or may not be itchy. Read More

    Griseofulvin and/or Terbinafine Induced Toxic Epidermal Necrolysis in an Adult Female Patient - A Case Report.
    Curr Drug Saf 2016 ;11(2):192-4
    Department of Pharmacology, Government Medical College and Sir Takhtsinhji General Hospital, Bhavnagar-364001, Gujarat, India.
    An 18 years old female patient, who was taking treatment for tinea cruris developed Toxic Epidermal Necrolysis (TEN) due to therapeutic dose of griseofulvin with concomitant use of terbinafine. Both the drugs were stopped; patient's condition was gradually improved after starting the treatment. As per WHO-UMC causality assessment criteria, association between reaction and drug was possible (for both griseofulvin and terbinafine). Read More

    [2011 Epidemiological Survey of Dermatomycoses in Japan].
    Med Mycol J 2015 ;56(4):J129-35
    Epidemiological Investigation Committee for Human Mycoses in the Japanese Society for Medical Mycology, Chairman and Reporter.
    An epidemiological survey of dermatomycoses and their causative fungus flora in Japan for 2011 was conducted in accordance with methods and criteria of the past four surveys. The survey covered a total number of 36,052 outpatients who visited 12 dermatological clinics throughout Japan. The results were as follows. Read More

    A study on etiologic agents and clinical manifestations of dermatophytosis in Yazd, Iran.
    Curr Med Mycol 2015 Dec;1(4):20-25
    Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background And Purpose: Dermatophytosis is one of the most common infections of skin, hair, and nails, caused by a group of keratinophilic fungi known as dermatophytes. Species identification of these fungi is of great significance from epidemiological and therapeutic points of view. The objective of the present study was to investigate dermatophytosis and its causative agents in patients, referring to the Central Mycology Laboratory of Yazd University of Medical Sciences, Yazd, Iran. Read More

    Dermatophytes and other associated fungi in patients attending to some hospitals in Egypt.
    Braz J Microbiol 2015 Jul-Sep;46(3):799-805. Epub 2015 Jul 1.
    Dermatology Department, Faculty of Medicine, Cairo University, Giza, Egypt .
    Dermatophytes are keratinophilic fungi that infect keratinized tissues causing diseases known as dermatophytoses. Dermatophytes are classified in three genera, Epidermophyton, Microsporum, and Trichophyton. This investigation was performed to study the prevalence of dermatomycosis among 640 patients being evaluated at the dermatology clinics at Kasr elainy, El-Husein and Said Galal hospitals in Cairo and Giza between January 2005 and December 2006. Read More

    Molecular Characterization and In Vitro Antifungal Susceptibility of 316 Clinical Isolates of Dermatophytes in Iran.
    Mycopathologia 2016 Feb 14;181(1-2):89-95. Epub 2015 Sep 14.
    Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Km 18 Khazarabad Road, P.O. Box 48175-1665, Sari, Iran.
    Dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. Various species of dermatophytes show significant differences in susceptibility to antifungals. Here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of Iran. Read More

    Dermatophytosis in patients with human immunodeficiency virus infection: clinical aspects and etiologic agents.
    Acta Trop 2015 Oct 19;150:111-5. Epub 2015 Jul 19.
    Division of Virology, Laboratory of Immunopathology Keizo Asami (LIKA), Department of Physiology and Pharmacology, Center of Biological Sciences, Federal University of Pernambuco, Brazil. Electronic address:
    Dermatophytosis in individuals with human immunodeficiency virus infection seems to manifest with atypical, multiple, or extensive lesions more frequently. In addition, there are reports of presentations with little inflammation, called anergics. Less common etiologic agents have been isolated in these individuals, such as Microsporum species. Read More

    The Immunologic Response to in Lower Extremity Fungal Infections.
    J Fungi (Basel) 2015 Jul 17;1(2):130-137. Epub 2015 Jul 17.
    Temple University School of Podiatric Medicine, 148 N. 8th St., Philadelphia, PA 19107, USA.
    Manifestations of infestations, such as tinea pedis, tinea cruris, and tinea corporis, are among the most common human skin diseases seen throughout the world. About 80% of patients presenting with acute dermatophytosis respond well to topical antifungal treatment. However, the remaining 20% of patients progress into a chronic state of dermatophytosis, which is resistant to antifungal treatment. Read More

    Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature.
    J Cutan Med Surg 2015 Mar-Apr;19(2):171-6. Epub 2015 Mar 11.
    SKINNOCENCE: The Skin Clinic & Research Centre, Haryana, IndiaDepartments of Dermatology and STD and Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.
    Background: Tinea indecisiva is characterized by concentric scaly rings simulating tinea imbricata but caused by dermatophytes other than Trichophyton concentricum.

    Objective: Tinea indecisiva has been rarely reported. We report a unique case and review of the previously reported cases, pathogenesis, and management. Read More

    Onychomycosis: epidemiology, diagnosis, and treatment in a changing landscape.
    J Drugs Dermatol 2015 Mar;14(3):223-33
    Onychomycosis is an often overlooked and/or undertreated disease. This may be in part due to an under appreciation among both physicians and patients of its impact on quality of life and the potential for significant complications, from tinea corporis and cruris, to bacterial superinfection. Some health care providers are unaware of the effective low-risk treatments currently available. Read More

    Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India.
    Springerplus 2014 9;3:134. Epub 2014 Mar 9.
    Superannuated as Professor Microbiology, Veterinary Microbiology, Haryana Agricultural University, Hisar, Haryana India.
    Dermatophytes are among the common fungal agents implicated in superficial skin infections worldwide. They include species of Trichophyton, Microsporum and Epidermophyton. In hot and humid climates of tropical and subtropical regions, the incidence of these pathogens is higher. Read More

    Diagnosis and management of tinea infections.
    Am Fam Physician 2014 Nov;90(10):702-10
    University of Iowa Carver College of Medicine, Iowa City, IA, USA.
    Tinea infections are caused by dermatophytes and are classified by the involved site. The most common infections in prepubertal children are tinea corporis and tinea capitis, whereas adolescents and adults are more likely to develop tinea cruris, tinea pedis, and tinea unguium (onychomycosis). The clinical diagnosis can be unreliable because tinea infections have many mimics, which can manifest identical lesions. Read More

    Evidence-based topical treatments for tinea cruris and tinea corporis: a summary of a Cochrane systematic review.
    Br J Dermatol 2015 Mar 9;172(3):616-41. Epub 2015 Feb 9.
    Department of Dermatology, B1-Q, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands.
    Tinea cruris and tinea corporis are common fungal infections. Most can be treated with a variety of topical antifungals. This review aimed to assess the evidence for the effectiveness and safety of topical treatments for tinea cruris and tinea corporis. Read More

    Luliconazole for the treatment of fungal infections: an evidence-based review.
    Core Evid 2014 24;9:113-24. Epub 2014 Sep 24.
    Department of Dermatology, Chacha Nehru Bal Chikitsalaya (Childrens Hospital), Delhi, India.
    Luliconazole is an imidazole antifungal agent with a unique structure, as the imidazole moiety is incorporated into the ketene dithioacetate structure. Luliconazole is the R-enantiomer, and has more potent antifungal activity than lanoconazole, which is a racemic mixture. In this review, we summarize the in vitro data, animal studies, and clinical trial data relating to the use of topical luliconazole. Read More

    Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature.
    J Cutan Med Surg 2014 Oct;18(5):1-6
    Background: Tinea indecisiva is characterized by concentric scaly rings simulating tinea imbricata but caused by dermatophytes other than Trichophyton concentricum.

    Objective: Tinea indecisiva has been rarely reported. We report a unique case and review of the previously reported cases, pathogenesis, and management. Read More

    Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis.
    J Invest Dermatol 2015 Mar 1;135(3):750-758. Epub 2014 Sep 1.
    Department of Dermatology, Jena University Hospital, Jena, Germany.
    Dermatophytes initiate dermatophytosis, but susceptibility to infection is dictated by host genetic factors, although the role of some of these-such as human beta-defensin 2 (hBD-2) genomic (DEFB4) copy number (CN) variation and its induction by IL-22-remains unclear. This was investigated in this cross-sectional study in 442 unrelated Caucasian subjects, including 195 healthy controls and 247 dermatophytosis patients who were divided into five subgroups according to clinical presentation. DNA samples were evaluated for DEFB4 CN variation by relative quantification using the comparative CT method, and serum hBD-2 and IL-22 levels were determined by ELISA. Read More

    Topical antifungal treatments for tinea cruris and tinea corporis.
    Cochrane Database Syst Rev 2014 Aug 4(8):CD009992. Epub 2014 Aug 4.
    Primary Care and Population Sciences, Faculty of Medicine, Aldermoor Health Centre, University of Southampton, Aldermoor Close, Southampton, UK, SO16 5ST.
    Background: Tinea infections are fungal infections of the skin caused by dermatophytes. It is estimated that 10% to 20% of the world population is affected by fungal skin infections. Sites of infection vary according to geographical location, the organism involved, and environmental and cultural differences. Read More

    A clinical and mycological study of dermatophytic infections.
    Indian J Dermatol 2014 May;59(3):262-7
    Department of Dermatology, Father Muller Medical College, Mangalore, Karnataka, India.
    Background: Dermatophytoses refer to superficial fungal infection of keratinized tissues caused by keratinophilic dermatophytes. According to observations worldwide, dermatophytoses are the most common of the superficial fungal infections. It is common in tropics and may present in epidemic proportions in areas with high rates of humidity. Read More

    Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris.
    Indian Dermatol Online J 2014 Apr;5(2):128-31
    Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India.
    Aims: To study and compare the efficacy and safety of topical terbinafine hydrochloride 1% cream and eberconazole nitrate 1% cream in localized tinea corporis and cruris.

    Methods And Materials: Patients were randomized after considering various inclusion and exclusion criteria into two groups. Group A (treated with terbinafine 1% cream for 3 weeks) and group B (treated with eberconazole 1% cream for 3 weeks). Read More

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