1,456 results match your criteria Tick-Borne Diseases Rocky Mountain Spotted Fever


New Jersey-Wide Survey of (Proteobacteria: Rickettsiaceae) in and (Acari: Ixodida: Ixodidae).

Am J Trop Med Hyg 2020 Jun 22. Epub 2020 Jun 22.

Department of Entomology, Center for Vector Biology, Rutgers University, New Brunswick, New Jersey.

For the last decade, the New Jersey (NJ) Department of Health has reported between 42 and 144 new cases each year of "spotted fever group rickettsiosis" (SFGR), a statistic that reflects uncertainty regarding which rickettsial agents (Proteobacteria: Rickettsiaceae: ) are infecting NJ residents. To identify the circulating in NJ ticks, we used a combination of conventional and qPCR approaches to screen 560 Say and 245 L. obtained from a 1-day state-wide surveillance in May 2018 and an additional 394 collected across NJ in 2013-2018. Read More

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http://dx.doi.org/10.4269/ajtmh.20-0145DOI Listing

Committee Opinion No. 399: Management of Tick Bites and Lyme Disease During Pregnancy.

J Obstet Gynaecol Can 2020 05;42(5):644-653

Halifax, NS.

Objective: Lyme disease is an emerging infection in Canada caused by the bacterium belonging to the Borrelia burgdorferi sensu lato species complex, which is transmitted via the bite of an infected blacklegged tick. Populations of blacklegged ticks continue to expand and are now established in different regions in Canada. It usually takes more than 24 hours of tick attachment to transfer B. Read More

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http://dx.doi.org/10.1016/j.jogc.2020.01.001DOI Listing

The Ability of the Invasive Asian Longhorned Tick Haemaphysalis longicornis (Acari: Ixodidae) to Acquire and Transmit Rickettsia rickettsii (Rickettsiales: Rickettsiaceae), the Agent of Rocky Mountain Spotted Fever, Under Laboratory Conditions.

J Med Entomol 2020 Apr 27. Epub 2020 Apr 27.

Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA.

The invasive Asian longhorned tick, Haemaphysalis longicornis Neumann, was first detected in the United States in 2017. It has since been found in 12 states, and there is concern that the tick's parthenogenetic ability and wide variety of host species may allow for broader dissemination. Of the tick-borne diseases endemic to the United States, Rocky Mountain spotted fever (RMSF), a rapidly progressive and potentially fatal disease caused by Rickettsia rickettsii, is the most severe. Read More

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http://dx.doi.org/10.1093/jme/tjaa076DOI Listing

Molecular detection of Rickettsia species in ticks collected in the Mexico-USA transboundary region.

Exp Appl Acarol 2020 Apr 5;80(4):559-567. Epub 2020 Apr 5.

Centro Nacional de Investigación Disciplinaria en Parasitología Veterinaria, INIFAP. AP 2016, Civac, CP 62550, Jiutepec, MOR, Mexico.

Zoonotic tick-borne diseases, including those caused by Rickettsia species, continue to have serious consequences for public health worldwide. One such disease that has emerged as a major problem in several countries of the American continent is the Rocky Mountain Spotted Fever (RMSF) caused by the bacterium Rickettsia rickettsii. Several tick species are capable of transmitting R. Read More

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http://dx.doi.org/10.1007/s10493-020-00483-5DOI Listing

Needlestick-Associated Rocky Mountain Spotted Fever, Brazil.

Emerg Infect Dis 2020 ;26(4):815-816

We report a fatal case of Rocky Mountain spotted fever (RMSF) in a man in Brazil without recent history of tick bites or environmental exposure. He received an accidental needlestick while working as a nurse. The nurse and his patient died. Read More

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http://dx.doi.org/10.3201/eid2604.191251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101093PMC
January 2020

Community-based prevention of epidemic Rocky Mountain spotted fever among minority populations in Sonora, Mexico, using a One Health approach.

Trans R Soc Trop Med Hyg 2020 Apr;114(4):293-300

Ministry of Public Health Sonora, General Directorate for Health Promotion and Disease Prevention, Paseo del Canal y Comonfort, Col. Centro, C.P. 83000, Hermosillo,Mexico.

Background: Rocky Mountain spotted fever (RMSF) is a significant public health problem in Sonora, Mexico, resulting in thousands of cases and hundreds of deaths. Outbreaks of RMSF are perpetuated by heavy brown dog tick infestations in and around homes. During 2009-2015, there were 61 RMSF cases and 23 deaths in a single community of Sonora (Community A). Read More

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http://dx.doi.org/10.1093/trstmh/trz114DOI Listing

Integrated tick control on a farm with the presence of capybaras in a Brazilian spotted fever endemic region.

Rev Bras Parasitol Vet 2019 Oct-Dec;28(4):671-676

Laboratório de Parasitologia Animal, Instituto Biológico, São Paulo, SP, Brasil.

Ticks of the Amblyomma cajennense complex present high infestation rates. These ticks transmit the bacterium Rickettsia rickettsii, which causes Brazilian Spotted Fever. For this reason, an integrated tick control system was adopted on a farm in the municipality of Itu, state of São Paulo. Read More

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http://dx.doi.org/10.1590/S1984-29612019096DOI Listing
January 2020

Spotted fever group rickettsiae canine serosurveillance near the US-Mexico border in California.

Zoonoses Public Health 2020 03 26;67(2):148-155. Epub 2019 Nov 26.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA.

Background: Dogs are vulnerable to pathogens transmitted by brown dog ticks. An epidemic of Rocky Mountain spotted fever (RMSF) is underway in Mexicali, a Mexican city bordering California affecting people and dogs; several human cases have been reported in California residents who travelled to Mexico. To evaluate risks of RMSF, we conducted seroprevalence surveys in Imperial County in 2016 and 2017 using dogs as sentinels. Read More

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http://dx.doi.org/10.1111/zph.12666DOI Listing

Fatal Brazilian Spotted Fever Associated with Dogs and Amblyomma aureolatum Ticks, Brazil, 2013.

Emerg Infect Dis 2019 12;25(12):2322-2323

In São Paulo metropolitan area, Brazil, Amblyomma aureolatum ticks are the main vector of Rickettsia rickettsii, which causes Brazilian spotted fever. In 2013, a boy in São Paulo died of Brazilian spotted fever associated with household dogs and A. aureolatum ticks. Read More

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http://dx.doi.org/10.3201/eid2512.191146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874244PMC
December 2019

Serosurvey of Rickettsia spp. in cats from a Brazilian spotted fever-endemic area.

Rev Bras Parasitol Vet 2019 Oct-Dec;28(4):713-721

Departamento de Biologia Celular e Molecular, Universidade Federal do Paraná - UFPR, Curitiba, PR, Brasil.

Rickettsia spp. bacteria are responsible for tick-borne diseases worldwide, mostly maintained by rickettsial amplifiers capybaras in Brazilian endemic areas. The campus of the University of São Paulo, in southeastern Brazil, is an area endemic for Brazilian spotted fever (BSF), with high density of capybaras and Amblyomma spp. Read More

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http://dx.doi.org/10.1590/S1984-29612019092DOI Listing
January 2020

Expanding Recognition of Rickettsiosis in Southern Arizona, 2016-2017.

Vector Borne Zoonotic Dis 2020 02 22;20(2):82-87. Epub 2019 Oct 22.

Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.

rickettsiosis is an emerging, tick-borne disease in the United States (US), transmitted by the bite of group ticks. Clinical manifestations include fever, headache, myalgia, maculopapular rash, and a characteristic eschar that forms at the site of the tick bite. Arizona's index case of rickettsiosis was reported in 2014. Read More

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http://dx.doi.org/10.1089/vbz.2019.2491DOI Listing
February 2020
1 Read

A human case of spotted fever caused by Rickettsia parkeri strain Atlantic rainforest and its association to the tick Amblyomma ovale.

Parasit Vectors 2019 Oct 11;12(1):471. Epub 2019 Oct 11.

Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Rickettsia parkeri strain Atlantic rainforest has emerged in Brazil during the last 10 years, with three laboratory-confirmed human cases. While these cases were epidemiologically associated with the tick Amblyomma ovale, in none of them the tick specimens that bit the patients could be identified.

Results: We report a clinical case of spotted fever rickettsiosis that was acquired in an Atlantic forest area in Bahia state, northeast Brazil. Read More

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http://dx.doi.org/10.1186/s13071-019-3730-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790035PMC
October 2019
5 Reads

Brazilian Spotted Fever Prevention through a Nonlethal Capybara Population Control Strategy.

Rev Soc Bras Med Trop 2019 3;52:e20190156. Epub 2019 Oct 3.

Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Programa de Pós-Graduação em Reprodução Animal, São Paulo, SP, Brasil.

Introduction: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.

Methods: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. Read More

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http://dx.doi.org/10.1590/0037-8682-0156-2019DOI Listing
October 2019
2 Reads

Laboratory Blood-Based Testing for Non-Lyme Disease Tick-Borne Infections at a National Reference Laboratory.

Am J Clin Pathol 2020 01;153(1):139-145

Quest Diagnostics, Secaucus, NJ.

Objectives: We evaluated trends in non-Lyme disease tick-borne disease (NLTBI) testing at a national reference laboratory.

Methods: Testing data performed at Quest Diagnostics during 2010 to 2016 were analyzed nationally and at the state level.

Results: Testing and positivity for most NLTBIs increased dramatically from 2010 through 2016 based on testing from a large reference laboratory. Read More

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http://dx.doi.org/10.1093/ajcp/aqz139DOI Listing
January 2020
1 Read

Molecular Detection of Spotted Fever Group Rickettsiae (Rickettsiales: Rickettsiaceae) in Dermacentor variabilis (Acari: Ixodidae) Collected Along the Platte River in South Central Nebraska.

J Med Entomol 2020 Feb;57(2):519-523

Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE.

Dermacentor variabilis is the predominant tick species in Nebraska and is presumed to be the primary vector of Rickettsia rickettsii associated with cases of Rocky Mountain spotted fever (RMSF). Interestingly, RMSF cases in Nebraska have increased on a year-to-year basis, yet the prevalence of R. rickettsii in D. Read More

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http://dx.doi.org/10.1093/jme/tjz167DOI Listing
February 2020
2 Reads

Susceptibility of to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever.

Am J Trop Med Hyg 2019 11;101(5):1091-1095

Department of Pathology, University of Texas Medical Branch, Galveston, Texas.

Rocky Mountain spotted fever (RMSF), caused by , is a severe tick-borne infection endemic to the Americas. Oral doxycycline is effective, but during severe life-threatening disease, intravenous therapy is recommended. Unfortunately, intravenous formulations of doxycycline are not always available. Read More

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http://dx.doi.org/10.4269/ajtmh.19-0445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838591PMC
November 2019
1 Read

Epidemiology of capybara-associated Brazilian spotted fever.

PLoS Negl Trop Dis 2019 09 6;13(9):e0007734. Epub 2019 Sep 6.

Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Brazilian spotted fever (BSF), caused by the bacterium Rickettsia rickettsii, has been associated with the transmission by the tick Amblyomma sculptum, and one of its main hosts, the capybara (Hydrochoerus hydrochaeris).

Methods: During 2015-2019, we captured capybaras and ticks in seven highly anthropic areas of São Paulo state (three endemic and four nonendemic for BSF) and in two natural areas of the Pantanal biome, all with established populations of capybaras.

Results: The BSF-endemic areas were characterized by much higher tick burdens on both capybaras and in the environment, when compared to the BSF-nonendemic areas. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750615PMC
September 2019
1 Read

Painless purple streaks on the arms and chest.

Cutis 2019 Jul;104(1):E8-E9

Department of Dermatology, Division of Pediatric Dermatology, Johns Hopkins University School of Medicine, Baltimore, USA.

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Knowledge and prevention of tickborne diseases among Hispanic and non-Hispanic residents of Maryland and Virginia.

Zoonoses Public Health 2019 11 3;66(7):805-812. Epub 2019 Sep 3.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado.

Tickborne diseases (TBDs) such as Lyme disease (LD), babesiosis, ehrlichiosis and Rocky Mountain spotted fever cause substantial morbidity and even mortality in the USA. Data indicate that Hispanic populations may be at greater risk for occupational exposure to ticks and disseminated LD; however, information on knowledge and practices of Hispanic populations regarding TBDs is limited. We surveyed 153 Hispanic and 153 non-Hispanic residents of Maryland and Virginia to assess awareness of TBDs, prevention practices and risk of tick encounters. Read More

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http://dx.doi.org/10.1111/zph.12627DOI Listing
November 2019
2 Reads

Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil.

Transfus Med 2019 Oct 30;29(5):358-363. Epub 2019 Aug 30.

Blood Center of Ribeirão Preto, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.

Objective: The objective of this study was to examine the Borrelia seroprevalence among blood donors in Southeast Brazil.

Background: There is evidence that Borrelia spirochetes are circulating in Brazil; however, there are no studies that characterise these bacteria and investigate their seroprevalence in the Brazilian population. Such a situation, combined with a recent outbreak of tick-borne Rocky Mountain spotted fever in the São Paulo state demonstrates the increasing role of ticks as arthropod vectors in Brazil. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/tme.12627
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http://dx.doi.org/10.1111/tme.12627DOI Listing
October 2019
2 Reads

Rickettsial infections of the central nervous system.

PLoS Negl Trop Dis 2019 08 29;13(8):e0007469. Epub 2019 Aug 29.

Aix-Marseille Univ, IRD, AP-HM, SSA, VITROME, IHU Mediterranée-Infection, Marseille, France.

As a result of migrations and globalization, people may face a possible increase in the incidence of central nervous system rickettsial infections (CNS R). These diseases, caused by Rickettsia species and transmitted to humans by arthropod bites, are putatively lethal. However, the diagnosis of CNS R is challenging and often delayed due to their nonspecific clinical presentation and the strict intracellular nature of rickettsiae. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715168PMC
August 2019
1 Read

Seroprevalence of spotted fever group rickettsiae in canines along the United States-Mexico border.

Zoonoses Public Health 2019 12 23;66(8):918-926. Epub 2019 Aug 23.

US-Mexico Unit, Division of Global Migration and Quarantine, NCEZID, CDC, Atlanta, Georgia.

Portions of northern Mexico are experiencing a re-emergence of Rocky Mountain spotted fever (RMSF), a tickborne disease caused by Rickettsia rickettsii, a member of the spotted fever group of rickettsiae (SFGR). Infection with R. rickettsii can result in serious and life-threatening illness in people and dogs. Read More

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http://dx.doi.org/10.1111/zph.12642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042707PMC
December 2019
3 Reads

Meningoencephalitis due to Spotted Fever Rickettsioses, Including Rocky Mountain Spotted Fever.

Clin Infect Dis 2020 Jun;71(1):188-195

Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: The spotted fever rickettsioses (SFR), including Rocky Mountain spotted fever, are tick-borne infections with frequent neurologic involvement. High morbidity and mortality make early recognition and empiric treatment critical. Most literature on SFR meningoencephalitis predates widespread magnetic resonance imaging (MRI) utilization. Read More

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http://dx.doi.org/10.1093/cid/ciz776DOI Listing
June 2020
2 Reads

Reported County-Level Distribution of the American Dog Tick (Acari: Ixodidae) in the Contiguous United States.

J Med Entomol 2020 01;57(1):131-155

Bacterial Diseases Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO.

In the United States, tick-borne diseases are increasing in incidence and cases are reported over an expanding geographical area. Avoiding tick bites is a key strategy in tick-borne disease prevention, and this requires current and accurate information on where humans are at risk for exposure to ticks. Based on a review of published literature and records in the U. Read More

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http://dx.doi.org/10.1093/jme/tjz119DOI Listing
January 2020
2 Reads

Antibody Titers Reactive With Rickettsia rickettsii in Blood Donors and Implications for Surveillance of Spotted Fever Rickettsiosis in the United States.

J Infect Dis 2020 Mar;221(8):1371-1378

Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta.

Background: Since 2000, the reported prevalence of tick-borne spotted fever rickettsiosis has increased considerably. We compared the level of antibody reactivity among healthy blood donors from 2 widely separated regions of the United States and evaluated the impact of antibody prevalence on public health surveillance in one of these regions.

Methods: Donor serum samples were evaluated by indirect immunofluorescence antibody assay to identify immunoglobulin G (IgG) antibodies reactive with Rickettsia rickettsii. Read More

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http://dx.doi.org/10.1093/infdis/jiz316DOI Listing
March 2020
5 Reads

A Suspected Case of Rocky Mountain Spotted Fever in an Adult Horse in the Southeastern United States.

J Equine Vet Sci 2019 Jul 11;78:134-137. Epub 2019 May 11.

Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC. Electronic address:

A 20-year-old Paint gelding was evaluated for fever of unknown origin. History and clinical signs were consistent with potential tick-borne disease. Samples were collected and submitted for tick-borne disease panel, herpes virus, complete blood count, and serum biochemistry. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07370806193005
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http://dx.doi.org/10.1016/j.jevs.2019.05.003DOI Listing
July 2019
12 Reads

A Cluster of Cases of Rocky Mountain Spotted Fever in an Area Of Colombia Not Known to be Endemic for This Disease.

Am J Trop Med Hyg 2019 08;101(2):336-342

Universidad de Antioquia, Medellín, Antioquia, Colombia.

Rocky Mountain spotted fever (RMSF) has been reported in Colombia since 1937. Most recent outbreaks were in 2006-2008, followed by the absence of recognized cases. This report describes new clinical cases of RMSF and epidemiologic investigations. Read More

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http://dx.doi.org/10.4269/ajtmh.18-1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685563PMC
August 2019
14 Reads

Fatal Rickettsia rickettsii infection in a child, Northwestern Colombia, 2017.

Ticks Tick Borne Dis 2019 08 24;10(5):995-996. Epub 2019 May 24.

Grupo Epidemiología, Facultad Nacional de Salud Pública, Universidad de Antioquia, Medellín, Colombia.

This report describes a new lethal case of Rickettsia rickettsii infection in a child from Northwestern Colombia, after ten years of the last outbreaks in the same region. Colombian public-health authorities should consider to include this severe rickettsiosis in the compulsory-reporting diseases, with the aim of knowing its burden in the country. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2019.05.009DOI Listing
August 2019
13 Reads

HLA-B27 spondyloarthritis and spotted fever rickettsiosis: case-based review.

Rheumatol Int 2019 Sep 27;39(9):1643-1650. Epub 2019 May 27.

Division of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.

Rickettsia rickettsii, a tick borne disease, is the pathogen responsible for inducing Rocky Mountain Spotted Fever (RMSF), an illness that can progress to fulminant multiorgan failure and death. We present a case where R. rickettsii, acquired on a camping trip, precipitated a flare of peripheral arthritis and episcleritis in an HLA-B27 positive patient. Read More

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http://link.springer.com/10.1007/s00296-019-04330-8
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http://dx.doi.org/10.1007/s00296-019-04330-8DOI Listing
September 2019
28 Reads

The Transcriptome of the Salivary Glands of Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Infection.

Front Physiol 2019 3;10:529. Epub 2019 May 3.

Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.

The salivary glands (SG) of ixodid ticks play a pivotal role in blood feeding, producing both the cement and the saliva. The cement is an adhesive substance that helps the attachment of the tick to the host skin, while the saliva contains a rich mixture of antihemostatic, anti-inflammatory, and immunomodulatory substances that allow ticks to properly acquire the blood meal. The tick saliva is also a vehicle used by several pathogens to be transmitted to the vertebrate host, including various bacterial species from the genus . Read More

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http://dx.doi.org/10.3389/fphys.2019.00529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509419PMC
May 2019
5 Reads

Long term neurologic sequelae in a Mexican rocky mountain spotted fever case.

Braz J Infect Dis 2019 Mar - Apr;23(2):121-123. Epub 2019 May 16.

Universidade Federal do Espírito Santo, Health Science Center, Postgraduate Program in Infectious Diseases, Vitória, ES, Brazil.

During the second half of the twentieth century, neurologic sequelae associated with central nervous system impairment caused by Rickettsia rickettsii were studied widely and exclusively in the United States. We present the case of a Mexican pediatric patient with neurologic sequelae 10 years after an acute infection by R. rickettsii. Read More

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http://dx.doi.org/10.1016/j.bjid.2019.04.006DOI Listing
July 2019
7 Reads

Unbiased Assessment of Abundance of sensu lato Ticks, Canine Exposure to Spotted Fever Group , and Risk Factors in Mexicali, México.

Am J Trop Med Hyg 2019 07;101(1):22-32

Dirección de Enseñanza y Vinculación, Instituto de Servicios de Salud Pública del Estado de Baja California, Mexicali, México.

An epidemic of Rocky Mountain spotted fever (RMSF) is ongoing in Mexicali, México. We visited 100 neighborhoods with diagnosed human cases and 100 control neighborhoods to evaluate knowledge of the epidemic; obtain data on the spatial distribution of dogs, canine seroprevalence and active infection, tick infestations, and presence of rickettsial DNA in ticks; and evaluate risk factors for human cases, seropositivity, and tick infestation within an unbiased study design. The majority (80%) of residents had heard of RMSF, but only 48% used acaricides in the home or on dogs. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609199PMC
July 2019
7 Reads
2.699 Impact Factor

The rash with maculopapules and fever in adults.

Clin Dermatol 2019 Mar - Apr;37(2):109-118. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

There is a broad differential diagnosis for the presentation of fever and maculopapular rash in an adult. Although some causative conditions are benign, others are medical emergencies that require prompt diagnosis. We describe various conditions that result in a fever and maculopapular rash in adults. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2018.12.004DOI Listing
September 2019
17 Reads

National Surveillance Data Show Increase in Spotted Fever Rickettsiosis: United States, 2016-2017.

Am J Public Health 2019 05;109(5):719-721

All of the authors are with the National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.

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https://ajph.aphapublications.org/doi/10.2105/AJPH.2019.3050
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http://dx.doi.org/10.2105/AJPH.2019.305038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459631PMC
May 2019
26 Reads

Multistate Survey of American Dog Ticks () for Species.

Vector Borne Zoonotic Dis 2019 09 3;19(9):652-657. Epub 2019 Apr 3.

Rickettsial Zoonoses Branch, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, Georgia.

, a common human-biting tick found throughout the eastern half and along the west coast of the United States, is a vector of multiple bacterial pathogens. Historically, has been considered a primary vector of , the causative agent of Rocky Mountain spotted fever. A total of 883 adult , collected between 2012 and 2017 from various locations in 12 states across the United States, were screened for rickettsial DNA. Read More

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http://dx.doi.org/10.1089/vbz.2018.2415DOI Listing
September 2019
13 Reads

Fiebre manchada de las montañas rocosas en un hospital pediátrico en el noreste de México.

Bol Med Hosp Infant Mex 2019 ;76(2):104-105

Departamento de Enseñanza e Investigación, Hospital Infantil del Estado de Sonora, Hermosillo, Sonora, México.

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http://dx.doi.org/10.24875/BMHIM.19000178DOI Listing
February 2020

Clinical Determination of Brain Death in Children Supported by Extracorporeal Membrane Oxygenation.

Neurocrit Care 2019 10;31(2):304-311

Division of Neurology, Children's National Medical Center, 111 Michigan Avenue NW, Washington, DC, 20010, USA.

Background/objective: Children supported by extracorporeal membrane oxygenation (ECMO) are at risk of catastrophic neurologic injury and brain death. Timely determination of brain death is important for minimizing psychological distress for families, resource allocation, and organ donation. Reports of successful determination of brain death in pediatric patients supported by ECMO are limited. Read More

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http://dx.doi.org/10.1007/s12028-019-00700-zDOI Listing
October 2019
6 Reads

Diagnostic Methods Used to Classify Confirmed and Probable Cases of Spotted Fever Rickettsioses - United States, 2010-2015.

MMWR Morb Mortal Wkly Rep 2019 Mar 15;68(10):243-246. Epub 2019 Mar 15.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC.

Spotted fever rickettsioses (SFR), including Rocky Mountain spotted fever (RMSF), are nationally notifiable diseases in the United States caused by spotted fever group Rickettsia. The annual incidence of SFR increased from 1.7 cases per 1 million persons in 2000 to 13. Read More

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http://dx.doi.org/10.15585/mmwr.mm6810a3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421962PMC
March 2019
8 Reads

Circulation of spotted fever group rickettsiae among dogs seropositive for Leishmania spp. in an urban area of Brazil.

Rev Soc Bras Med Trop 2019 Feb 21;52:e20180133. Epub 2019 Feb 21.

Departamento de Patologia e Clínica Veterinária, Universidade Federal Fluminense, Niterói, RJ, Brasil.

Introduction: Dogs play an epidemiological role in several vector-borne diseases that affect human and animal health worldwide. We aimed to identify rickettsial circulation among dogs with canine visceral leishmaniasis (CVL) from a region endemic for both diseases.

Methods: CVL-seropositive dogs were screened for spotted fever group rickettsiae using an indirect immunofluorescence assay. Read More

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http://dx.doi.org/10.1590/0037-8682-0133-2018DOI Listing
February 2019
11 Reads

Salivary PGE Modulates the Dendritic Cell- Interactions and .

Front Immunol 2019 4;10:118. Epub 2019 Feb 4.

Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

is an important vector of , causative agent of Rocky Mountain spotted fever and the most lethal tick-borne pathogen affecting humans. To feed on the vertebrate host's blood, secretes a salivary mixture, which may interact with skin resident dendritic cells (DCs) and modulate their function. The present work was aimed at depicting the saliva-host DC network and the biochemical nature of the immunomodulatory component(s) involved in this interface. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369204PMC
December 2019
12 Reads

The Rickettsioses: A Practical Update.

Authors:
Lucas S Blanton

Infect Dis Clin North Am 2019 03;33(1):213-229

Department of Internal Medicine, Division of Infectious Diseases, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0435, USA. Electronic address:

Rickettsia are small, obligately intracellular, gram-negative bacilli. They are distributed among a variety of hematophagous arthropod vectors and cause illness throughout the world. Rickettsioses present as an acute undifferentiated febrile illness and are often accompanied by headache, myalgias, and malaise. Read More

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http://dx.doi.org/10.1016/j.idc.2018.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364315PMC
March 2019
48 Reads

Repellency effect of flumethrin pour-on formulation against vectors of Crimean-Congo haemorrhagic fever.

East Mediterr Health J 2019 Jan 23;24(11):1082-1087. Epub 2019 Jan 23.

Department of Medical Entomology and Vector Control, School of Public Health and National Institute of Health Research, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.

Background: Ticks are able to transmit important diseases to humans, including Rocky Mountain spotted fever, Q fever, Crimean-Congo haemorrhagic fever, summer Russian encephalitis, and relapsing fever.

Aims: To determine the repellency effect of 1% flumethrin pour-on formulation against hard ticks.

Methods: The concentration of flumethrin pour-on formulation was 1 mg/10 kg body weight and was administered on the dorsal midline from the head to the base of the tail. Read More

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http://dx.doi.org/10.26719/emhj.18.004DOI Listing
January 2019
13 Reads

Hosts mobility and spatial spread of Rickettsia rickettsii.

PLoS Comput Biol 2018 12 26;14(12):e1006636. Epub 2018 Dec 26.

Robert Koch-Institute, Berlin, Germany.

There are a huge number of pathogens with multi-component transmission cycles, involving amplifier hosts, vectors or complex pathogen life cycles. These complex systems present challenges in terms of modeling and policy development. A lethal tick-borne infectious disease, the Brazilian Spotted Fever (BSF), is a relevant example of that. Read More

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http://dx.doi.org/10.1371/journal.pcbi.1006636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324817PMC
December 2018
8 Reads

Rickettsia rickettsii Whole-Cell Antigens Offer Protection against Rocky Mountain Spotted Fever in the Canine Host.

Infect Immun 2019 02 24;87(2). Epub 2019 Jan 24.

Center of Excellence for Vector-Borne Diseases, Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University (CVM-KSU), Manhattan, Kansas, USA

Rocky Mountain spotted fever (RMSF) is a potentially fatal tick-borne disease in people and dogs. RMSF is reported in the United States and several countries in North, Central, and South America. The causative agent of this disease, , is transmitted by several species of ticks, including , , and RMSF clinical signs generally include fever, headache, nausea, vomiting, muscle pain, lack of appetite, and rash. Read More

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http://iai.asm.org/lookup/doi/10.1128/IAI.00628-18
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http://dx.doi.org/10.1128/IAI.00628-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346123PMC
February 2019
47 Reads

Fatal case of co-infected of rickettiosis and dengue virus in Mexico

Rev Med Inst Mex Seguro Soc 2018 Oct 25;56(3):320-322. Epub 2018 Oct 25.

Universidad de Sonora, Departamento de Medicina y Ciencias de la Salud. Hermosillo, Sonora, México

Background: Rocky Mountain spotted fever (RMSF) is a disease spread by an infected tick and it is lethal if patient is not treated on time. Symptom similarities with other exanthematous diseases may delay the diagnosis, which leads to its mortality.

Clinical Case: We show the lethal case of a patient with medical record of high blood pressure and no history of travel, who lived in Sonora, Mexico. Read More

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October 2018
12 Reads

Rickettsia rickettsii Co-feeding Transmission among Amblyomma aureolatum Ticks.

Emerg Infect Dis 2018 11;24(11):2041-2048

Amblyomma aureolatum ticks are vectors of Rickettsia rickettsii, the etiologic agent of Rocky Mountain spotted fever in Brazil. Maintenance of R. rickettsii in nature depends on horizontal transmission along tick generations. Read More

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http://dx.doi.org/10.3201/eid2411.180451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200015PMC
November 2018
13 Reads

[Fiebre manchada de montañas rocosas: experiencia en 5 años de vigilancia activa en un hospital pediátrico de segundo nivel en el noreste de México].

Bol Med Hosp Infant Mex 2018 ;75(5):303-308

Unidad de Investigación Medicina Basada en Evidencias, Hospital Infantil de México Federico Gómez, Ciudad de México. México.

Introducción: La fiebre manchada de las montañas rocosas (FMMR) es causada por Rickettsia rickettsii. En Coahuila, la región de la Comarca Lagunera se considera una zona endémica. No se han reportado casos en la zona sur del estado, específicamente en la ciudad de Saltillo. Read More

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http://dx.doi.org/10.24875/BMHIM.M18000034DOI Listing
October 2019
9 Reads

Exposure to Ticks and their Pathogens in Northeast Missouri.

Authors:
Deborah A Hudman

Mo Med 2018 Jul-Aug;115(4):374-379

Deborah A. Hudman, MS, is in the Department of Microbiology/Immunology, A.T. Still University Kirksville College of Osteopathic Medicine.

While the prevalence of human pathogens has been quantified in ticks in Adair County, Missouri, the prevalence of residents acquiring tick-borne diseases and seeking medical treatment has not. A public survey (n=109) revealed that 96% of respondents reported finding attached ticks on their person; of these, 38% developed symptoms post tick bite; of these, 55% reported consultation with a health care provider. Overall, 89% of practitioners surveyed had treated at least one patient for tick-borne disease. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140261PMC
August 2019
15 Reads

Basic reproduction number for the Brazilian Spotted Fever.

J Theor Biol 2018 12 15;458:119-124. Epub 2018 Sep 15.

Laboratory of Epidemiology and Biostatistics, Department of Preventive Veterinary Medicine and Animal Health, University of São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo 05508-270 Brazil.

Brazilian Spotted Fever (BSF) is an emerging and lethal disease in South America which basic reproduction number (R) is unknown. Calculating R for this disease is crucial to design control interventions and prevent human deaths. BSF endemic areas are related to the presence of capybaras Hydrochoerus hydrochaeris, amplifier hosts of Rickettsia rickettsii and primary hosts of the tick Amblyomma sculptum, main vector of the agent in this area. Read More

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http://dx.doi.org/10.1016/j.jtbi.2018.09.011DOI Listing
December 2018

Progressive Rash Involving the Hands and Feet.

Am Fam Physician 2018 06;97(12):815-817

Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

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June 2018
7 Reads