1,291 results match your criteria Tick-Borne Diseases Relapsing Fever


Prevalence of Bacterial and Protozoan Pathogens in Ticks Collected from Birds in the Republic of Moldova.

Microorganisms 2022 May 27;10(6). Epub 2022 May 27.

Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany.

Epidemiological knowledge on pathogens in ticks feeding on birds in Moldova is scarce. To reduce this gap of information, a total of 640 migrating and native birds of 40 species were caught from 2012 to 2015 and examined for the presence of ticks in the Republic of Moldova. Altogether, 262 ticks belonging to five tick species ( n = 245, n = 12, n = 2, n = 2 (only males), n = 1) were collected from 93 birds. Read More

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Bacteria and protozoa with pathogenic potential in Ixodes ricinus ticks in Viennese recreational areas.

Wien Klin Wochenschr 2022 Jun 10. Epub 2022 Jun 10.

Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, 1090, Vienna, Austria.

Ixodes ricinus is the most relevant vector for tick-borne diseases in Austria and responsible for the transmission of Borrelia burgdorferi sensu lato (s. l.), which causes Lyme borreliosis in humans; however, also other bacteria and protozoa can be found in ticks and have the potential of infecting people and animals. Read More

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Historical overview and update on relapsing fever group Borrelia in Latin America.

Parasit Vectors 2022 Jun 8;15(1):196. Epub 2022 Jun 8.

Latin American Group for the Study of Ornithodoros-borne Borrelioses (Grupo Latinoamericano Para el Estudio de Borreliosis Transmitidas Por Ornithodoros [GLEBTO]), Bogotá, Colombia.

Relapsing fever group Borrelia (RFGB) are motile spirochetes transmitted to mammalian or avian hosts through the bite of hematophagous arthropods, such as soft ticks (Argasidae), hard ticks (Ixodidae) and the human clothing lice. RFGB can infect pets such as dogs and cats, as well as birds, cattle and humans. Borrelia recurrentis, B. Read More

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Comparative genomics of the Western Hemisphere soft tick-borne relapsing fever borreliae highlights extensive plasmid diversity.

BMC Genomics 2022 May 31;23(1):410. Epub 2022 May 31.

Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

Background: Tick-borne relapsing fever (TBRF) is a globally prevalent, yet under-studied vector-borne disease transmitted by soft and hard bodied ticks. While soft TBRF (sTBRF) spirochetes have been described for over a century, our understanding of the molecular mechanisms facilitating vector and host adaptation is poorly understood. This is due to the complexity of their small (~ 1. Read More

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Suppressive effects of Ixodes persulcatus sialostatin L2 against Borrelia miyamotoi-stimulated immunity.

Ticks Tick Borne Dis 2022 Jul 29;13(4):101963. Epub 2022 Apr 29.

Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan; Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.

Borrelia miyamotoi infection is an emerging tick-borne disease that causes hard tick-borne relapsing fever. B. miyamotoi is transmitted through the bite of ticks, including Ixodes persulcatus. Read More

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Infection and seroprevalence of Borrelia persica in domestic cats and dogs in Israel.

Parasit Vectors 2022 May 10;15(1):102. Epub 2022 May 10.

The Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, P.O. Box 12, 761001, Rehovot, Israel.

Background: Relapsing fever borreliosis is an infectious disease caused by bacteria of the genus Borrelia, inflicting recurrent episodes of fever and spirochetemia in humans. Borrelia persica, the causative agent of relapsing fever in Israel, is prevalent over a broad geographic area that extends from India to Egypt. It is transmitted by the soft tick Ornithodoros tholozani and causes disease in humans as well as domestic cats and dogs. Read More

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Detection of Borrelia miyamotoi in Ixodes ricinus ticks in Southern Moravia - risk for public health.

Epidemiol Mikrobiol Imunol 2022 ;71(1):57-59

Borrelia miyamotoi is an emerging tick-borne pathogen. The vector is ticks of the Ixodes ricinus complex, causing relapsing fever- like disease and widespread in the temperate zone of the Northern Hemisphere. The present study documents the prevalence of B. Read More

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A Comparative Study of Body Lice and Bed Bugs Reveals Factors Potentially Involved in Differential Vector Competence for the Relapsing Fever Spirochete Borrelia recurrentis.

Infect Immun 2022 May 6;90(5):e0068321. Epub 2022 Apr 6.

University of South Dakotagrid.267169.d, Sanford School of Medicine, Division of Basic Biomedical Sciences, Vermillion, South Dakota, USA.

Borrelia recurrentis is the causative agent of louse-borne relapsing fever and the only species transmitted by an insect rather than a tick vector. While bed bugs (Cimex lectularius L.) are not established vectors of any human pathogens, a recent study reported that they may be competent vectors of B. Read More

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The influence of local environmental factors in southwestern Poland on the abundance of Ixodes ricinus and prevalence of infection with Borrelia burgdorferi s.l. and B. miyamotoi.

Parasitol Res 2022 Jun 26;121(6):1575-1585. Epub 2022 Mar 26.

Department of Bioinformatics and Genomics, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.

Ticks are important ectoparasites and vectors of pathogens that cause disease in humans and animals. The natural habitat of Ixodes ricinus ticks is forests, which are convenient habitats to search for hosts, including reservoir hosts, and therefore can be an important habitat source of tick-borne pathogens. The aim of the study was to assess the usefulness of detailed forest habitat-type maps to estimate the tick-borne risk at a local scale (Lower Silesia, SW Poland). Read More

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Early Transcriptional Changes in the Midgut of after Feeding and Infection with .

Microorganisms 2022 Feb 28;10(3). Epub 2022 Feb 28.

Institute of Infectology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.

Studies on tick-pathogen-host interactions are helping to identify candidates for vaccines against ticks and tick-borne diseases and to discover potent bioactive tick molecules. The tick midgut is the main tissue involved in blood feeding and, moreover, the first organ to have contact with pathogens ingested through the blood meal. As little is known about the molecular biology of feeding and tick defence mechanisms against microorganisms, but important for understanding vector-pathogen interactions, we explored the early transcriptional changes in the midgut of after feeding and in response to challenge with the relapsing-fever spirochete using the Ion S5XL platform. Read More

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February 2022

Mechanism of Borrelia immune evasion by FhbA-related proteins.

PLoS Pathog 2022 03 18;18(3):e1010338. Epub 2022 Mar 18.

Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.

Immune evasion facilitates survival of Borrelia, leading to infections like relapsing fever and Lyme disease. Important mechanism for complement evasion is acquisition of the main host complement inhibitor, factor H (FH). By determining the 2. Read More

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The arginine deaminase system plays distinct roles in Borrelia burgdorferi and Borrelia hermsii.

PLoS Pathog 2022 03 14;18(3):e1010370. Epub 2022 Mar 14.

Laboratory of Bacteriology, Gene Regulation Section, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.

Borrelia species are amino acid auxotrophs that utilize di- and tri- peptides obtained through their oligopeptide transport system to supply amino acids for replicative growth during their enzootic cycles. However, Borrelia species from both the Lyme disease (LD) and relapsing fever (RF) groups harbor an amino acid transport and catabolism system, the Arginine Deiminase System (ADI), that could potentially augment intracellular L-arginine required for growth. RF spirochetes contain a "complete", four gene ADI (arcA, B, D, and C) while LD spirochetes harbor arcA, B, and sometimes D but lack arcC (encoding carbamate kinase). Read More

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Tick borne relapsing fever - a systematic review and analysis of the literature.

PLoS Negl Trop Dis 2022 02 16;16(2):e0010212. Epub 2022 Feb 16.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

Tick borne relapsing fever (TBRF) is a zoonosis caused by various Borrelia species transmitted to humans by both soft-bodied and (more recently recognized) hard-bodied ticks. In recent years, molecular diagnostic techniques have allowed to extend our knowledge on the global epidemiological picture of this neglected disease. Nevertheless, due to the patchy occurrence of the disease and the lack of large clinical studies, the knowledge on several clinical aspects of the disease remains limited. Read More

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February 2022

[Borreliosis and relapsing fever].

Rev Prat 2021 12;71(10):1113-1117

CRMVT, Région Sud, IHU-Méditerranée Infection, Marseille, Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.

BORRELIOSIS AND RELAPSING feverrelapsing fevers borreliosis (RFB) are caused by bacteria of the genus Borrelia, within the spirochete's family, transmitted to Humans by arthropods (lice Pediculus humanus, soft ticks of the genus Ornithodoros, or hard ticks for one of them). The RFB transmitted by body lice is cosmopolitan and occurs during epidemics in the context of major crises (promiscuity, precarious hygiene conditions, food crises, etc.). Read More

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December 2021

Biodiversity Indices and Medically Importance of Ticks in North Khorasan Province, Northeast of Iran.

J Arthropod Borne Dis 2021 Jun 30;15(2):187-195. Epub 2021 Jun 30.

Department of Medical Entomology and Vector Control School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Ticks are considered as the main vectors for the transmission of various pathogens such as relapsing fever and CCHF to humans. This study was investigated the biodiversity indices and medically importance of ticks in North Khorasan Province, Northeast of Iran during 2015-2019.

Methods: Specimens were captured from infested ruminants including cows, sheep, and goats. Read More

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Diversity of Hard Tick Populations and Their Geographical Variations in Northwestern Iran.

J Arthropod Borne Dis 2021 Jun 30;15(2):179-186. Epub 2021 Jun 30.

Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Ticks are forced vertebrate ectoparasites, including humans, and are vectors of serious diseases such as Crimean Congo Hemorrhagic Fever, Relapsing Fever, and various forms of encephalitis. Spatial assessment of the prevalence of ticks and detection of high risk areas for tick-borne disease transmission and evaluation of ecological measures are key aims of this research.

Methods: Ticks were collected using standard methods from 27 villages in the region of Sarab County in north-eastern Iran during the four seasons of 2018-2019 and identified using valid keys. Read More

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Prevalence of relapsing fever spirochete Borrelia miyamotoi in Ixodes ricinus ticks from eastern Slovakia.

Zoonoses Public Health 2022 05 29;69(3):242-247. Epub 2022 Jan 29.

Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic.

Borrelia miyamotoi, recurrent fever borrelia, pathogenic to humans, has been found recently in Ixodes ricinus ticks. There is still little information about its circulation in nature and potential local impact on human health as well as the occurrence in natural localities. In our study, a total of 1609 ticks (745 nymphs, 358 females and 506 males) collected from different localities in eastern Slovakia were analysed using a polymerase chain reaction targeting a gene encoding glycerophosphodiester phosphodiesterase (glpQ), which is specific to the Borrelia species in the relapsing fever group. Read More

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A proteomics informed by transcriptomics insight into the proteome of Ornithodoros erraticus adult tick saliva.

Parasit Vectors 2022 Jan 3;15(1). Epub 2022 Jan 3.

Proteomics Section, Central Service for Experimental Research, University of Valencia, Carrer del Dr. Moliner, 50, 46100, Burjassot, Spain.

Background: The argasid tick Ornithodoros erraticus is the main vector of tick-borne human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin. The prevention and control of these diseases would greatly benefit from the elimination of O. erraticus populations, and anti-tick vaccines are envisaged as an effective and sustainable alternative to chemical acaricide usage for tick control. Read More

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January 2022

The bacterial biome of ticks and their wildlife hosts at the urban-wildland interface.

Microb Genom 2021 12;7(12)

Harry Butler Institute, Murdoch University, Murdoch, Western Australia, 6150, Australia.

Advances in sequencing technologies have revealed the complex and diverse microbial communities present in ticks (Ixodida). As obligate blood-feeding arthropods, ticks are responsible for a number of infectious diseases that can affect humans, livestock, domestic animals and wildlife. While cases of human tick-borne diseases continue to increase in the northern hemisphere, there has been relatively little recognition of zoonotic tick-borne pathogens in Australia. Read More

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December 2021

Vaccines Against Vector-Borne Diseases.

Methods Mol Biol 2022 ;2411:269-286

Department of Veterinary Medicine, University of Maryland, College Park and Virginia-Maryland Regional College of Veterinary Medicine, College Park, MD, USA.

Arthropod vectors account for a number of animal and human diseases, posing substantial threats to health and safety on a global scale. Ticks are considered as one of the most prominent vectors, as they can parasitize almost any vertebrate class and transmit a multitude of infectious diseases, particularly ones that affect humans and domestic animals. While various tick species elicit different tick-borne infections in specific geographic regions, single species can have widespread effects, such as blacklegged ticks, which are widely distributed across the eastern United States and can transmit a variety of infections, including Lyme borreliosis, anaplasmosis, relapsing fever disease, ehrlichiosis, babesiosis, and Powassan virus disease. Read More

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January 2022

Diversity and distribution of the tick-borne relapsing fever spirochete Borrelia turicatae.

PLoS Negl Trop Dis 2021 11 23;15(11):e0009868. Epub 2021 Nov 23.

Department of Pediatrics and the National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

Borrelia turicatae is a causative agent of tick-borne relapsing fever (TBRF) in the subtropics and tropics of the United States and Latin America. Historically, B. turicatae was thought to be maintained in enzootic cycles in rural areas. Read More

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November 2021

An immunosuppressed woman in her seventies with night sweats and weight loss.

Tidsskr Nor Laegeforen 2021 11 22;141(17). Epub 2021 Nov 22.

Background: Candidatus Neoehrlichia mikurensis is an emerging tick-borne pathogen with widespread distribution in Ixodes ricinus ticks in Europe and Asia. It has been found to cause chronic infections, particularly in immunosuppressed individuals. Common symptoms include relapsing fever, night sweats and thromboembolic episodes, likely due to endovascular infection. Read More

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November 2021

Borrelioses in Brazil: Is it time to consider tick-borne relapsing fever a neglected disease in Brazil?

Rev Soc Bras Med Trop 2021 12;54:e0443. Epub 2021 Nov 12.

Universidade Estadual de Campinas, Hospital de Clínicas, Seção de Epidemiologia Hospitalar, Campinas, SP, Brasil.

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November 2021

Causing Thrombosis and Relapsing Fever in a Lymphoma Patient Receiving Rituximab.

Microorganisms 2021 Oct 12;9(10). Epub 2021 Oct 12.

Department of Clinical Microbiology, Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden.

, an intracellular tick-borne bacterium not detected by routine blood culture, is prevalent in ticks in Scandinavia, Central Europe and Northern Asia, and may cause long-standing fever, nightly sweats, migrating pain, skin rashes and thromboembolism, especially in patients treated with rituximab. The multiple symptoms may raise suspicion of both infection, inflammation and malignancy, and lead in most cases to extensive medical investigations across many medical specialist areas and a delay of diagnosis. We describe a complex, albeit typical, case of neoehrlichiosis in a middle-aged splenectomised male patient with a malignant lymphoma, receiving treatment with rituximab. Read More

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October 2021

Modification of the multiplex plasmid PCR assay for Borrelia miyamotoi strain LB-2001 based on the complete genome sequence reflecting genomic rearrangements differing from strain CT13-2396.

Ticks Tick Borne Dis 2022 01 11;13(1):101843. Epub 2021 Oct 11.

Bacterial Diseases Branch, Division of Vector Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO United States.

The genome of Borrelia spp. consists of an approximate 1 megabase chromosome and multiple linear and circular plasmids. We previously described a multiplex PCR assay to detect plasmids in the North American Borrelia miyamotoi strains LB-2001 and CT13-2396. Read More

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January 2022

Surveillance and Molecular Identification of Borrelia Species in Ticks Collected at U.S. Army Garrison Humphreys, Republic of Korea, 2018-2019.

J Med Entomol 2022 01;59(1):363-371

Department of Microbiology, College of Medicine, Korea University, Seoul, Republic of Korea.

Tick-borne pathogens are contributing factors for the increased incidence of vector-borne diseases throughout the world, including Lyme borreliosis, one of the most prevalent spirochetes belonging to the Borrelia burgdorferi sensu lato group. The present study focused on the detection of Borrelia species from hard ticks collected at U.S. Read More

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January 2022

Laboratory Methods for Detection of Infectious Agents and Serological Response in Humans With Tick-Borne Infections: A Systematic Review of Evaluations Based on Clinical Patient Samples.

Front Public Health 2021 20;9:580102. Epub 2021 Sep 20.

Division of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

For the most important and well-known infections spread by ticks, Lyme borreliosis (LB) and tick-borne encephalitis (TBE), there are recommendations for diagnosis and management available from several health authorities and professional medical networks. However, other tick-borne microorganisms with potential to cause human disease are less known and clear recommendations on diagnosis and management are scarce. Therefore, we performed a systematic review of published studies and reviews focusing on evaluation of laboratory methods for clinical diagnosis of human tick-borne diseases (TBDs), other than acute LB and TBE. Read More

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October 2021

Citizen Science Provides an Efficient Method for Broad-Scale Tick-Borne Pathogen Surveillance of Ixodes pacificus and Ixodes scapularis across the United States.

mSphere 2021 10 29;6(5):e0068221. Epub 2021 Sep 29.

Colorado State Universitygrid.47894.36, Fort Collins, Colorado, USA.

Tick-borne diseases have expanded over the last 2 decades as a result of shifts in tick and pathogen distributions. These shifts have significantly increased the need for accurate portrayal of real-time pathogen distributions and prevalence in hopes of stemming increases in human morbidity. Traditionally, pathogen distribution and prevalence have been monitored through case reports or scientific collections of ticks or reservoir hosts, both of which have challenges that impact the extent, availability, and accuracy of these data. Read More

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October 2021

Transovarial Transmission of by Its Tick Vector and Reservoir Host .

Microorganisms 2021 Sep 17;9(9). Epub 2021 Sep 17.

Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA.

Transovarial passage of relapsing fever spirochetes ( species) by infected female argasid ticks to their progeny is a widespread phenomenon. Yet this form of vertical inheritance has been considered rare for the North American tick infected with . A laboratory colony of was established from a single infected female and two infected males that produced a population of ticks with a high prevalence of transovarial transmission based on infection assays of single and pooled ticks feeding on mice and immunofluorescence microscopy of eggs and larvae. Read More

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September 2021

Ticks and their epidemiological role in Slovakia: from the past till present.

Biologia (Bratisl) 2022 17;77(6):1575-1610. Epub 2021 Sep 17.

Institute of Zoology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 06 Bratislava, Slovakia.

In Slovakia, 22 tick species have been found to occur to date. Among them, and marginally and have been identified as the species of public health relevance. Ticks in Slovakia were found to harbour and transmit zoonotic and/or potentially zoonotic agents such as tick-borne encephalitis virus (TBEV), spirochaetes of the sensu lato (s. Read More

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September 2021