11,799 results match your criteria Tick-Borne Diseases Lyme


Impact of four local anaesthetics on growth and viability of in vitro cultured Borrelia burgdorferi sensu stricto, Borrelia bavariensis and Borrelia afzelii.

Ticks Tick Borne Dis 2021 May 3;12(5):101735. Epub 2021 May 3.

Chair for Bacteriology and Mycology, Institute for Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU Munich, Munich, Germany. Electronic address:

Many local anaesthetics, including lidocaine, procaine and ropivacaine inhibit bacterial growth. This study investigates potential effects of these local anaesthetics on growth of Borrelia burgdorferi sensu stricto (Bbss), Borrelia bavariensis (Bbav) and Borrelia afzelii (Ba). For this purpose, Borrelia spp. Read More

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Endogenous and Borrowed Proteolytic Activity in the .

Microbiol Mol Biol Rev 2021 May 12;85(2). Epub 2021 May 12.

Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York, USA

SUMMARYThe spp. are tick-borne pathogenic spirochetes that include the agents of Lyme disease and relapsing fever. As part of their life cycle, the spirochetes traffic between the tick vector and the vertebrate host, which requires significant physiological changes and remodeling of their outer membranes and proteome. Read More

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A seroepidemiological investigation of Lyme disease in Qiongzhong County, Hainan Province in 2019-2020.

Ann Palliat Med 2021 Apr;10(4):4721-4727

Department of Internal Medicine, Shanghai Jiao Tong University Affiliated Tongren Hospital Hainan Branch/Qiongzhong Li and Miao Autonomous County People's Hospital, Qiongzhong, China.

Background: The incidence and prevalence of Lyme disease are expanding and rising, respectively, which constitutes a worldwide public health problem. The present study aimed to investigate the prevalence of Lyme disease (LD) in Qiongzhong County, Hainan, and to determine the LD infection level in the local population, so as to provide evidence for further local LD surveillance as well as effective prevention and treatment measures.

Methods: A total of 252 serum samples were collected from cases with suspected LD in Qiongzhong County, including 159 and 93 cases with joint and neurological symptoms, respectively. Read More

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Grappling with the tick microbiome.

Trends Parasitol 2021 May 4. Epub 2021 May 4.

Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06420, USA.

Ixodes scapularis and Ixodes pacificus are the predominant vectors of multiple human pathogens, including Borrelia burgdorferi, one of the causative agents of Lyme disease in North America. Differences in the habitats and host preferences of these closely related tick species present an opportunity to examine key aspects of the tick microbiome. While advances in sequencing technologies have accelerated a descriptive understanding of the tick microbiome, molecular and mechanistic insights into the tick microbiome are only beginning to emerge. Read More

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Recurrent bilateral chorioretinitis with positive Lyme serology: a case report.

J Med Case Rep 2021 May 4;15(1):253. Epub 2021 May 4.

Associated Retina Consultants, 1750 E. Glendale Ave, Phoenix, AZ, USA.

Background: It has been disputed whether Lyme is a true causative agent in posterior uveitis or an incidental finding.

Case Presentation: This report presents a case of a 33-year-old Caucasian female with a remote history of Lyme disease who presented with blurry vision in the right eye. Exam and imaging revealed a right active chorioretinitis and positive Lyme serology. Read More

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The Population Structure of Is Reflected by a Population Division of Its Vector.

Microorganisms 2021 Apr 27;9(5). Epub 2021 Apr 27.

National Reference Center for Borrelia, Bavarian Health and Food Safety Authority, 85764 Oberschleissheim, Germany.

Populations of vector-borne pathogens are shaped by the distribution and movement of vector and reservoir hosts. To study what impact host and vector association have on tick-borne pathogens, we investigated the population structure of using multilocus sequence typing (MLST). Novel sequences were acquired from questing ticks collected in multiple North African and European locations and were supplemented by publicly available sequences at the Borrelia Pubmlst database (accessed on 11 February 2020). Read More

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[CME/Answers: Musculoskeletal Manifestations of Lyme Disease].

Praxis (Bern 1994) 2021 Apr;110(6):299-300

Innere Medizin, Kantonsspital Graubünden, Chur.

Lyme disease is the most common vector-borne illness in Switzerland and Lyme arthritis the most prevalent manifestation of late-stage Lyme disease. It presents as a monoarthitis or oligoarthritis in large joints, often involving the knee. Such a clinical presentation, together with positive Lyme serologies or polymerase chain reactions from synovial fluid/tissue, is considered diagnostic. Read More

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Examining prevalence and diversity of tick-borne pathogens in questing ticks in California.

Appl Environ Microbiol 2021 Apr 23. Epub 2021 Apr 23.

Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86001, United States of America.

Tick-borne diseases in California include Lyme disease (caused by ), infections with , and human granulocytic anaplasmosis (caused by ). We surveyed multiple sites and habitats (woodland, grassland, coastal chaparral) in California to describe spatial patterns of tick-borne pathogen prevalence in western black-legged ticks (). We found that several species of and - were observed in habitats such as coastal chaparral that does not harbor obvious reservoir host candidates. Read More

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Monitoring of pathogenic Borrelia burgdorferi sensu lato in the Almaty oblast, Kazakhstan.

Ticks Tick Borne Dis 2021 Apr 9;12(4):101725. Epub 2021 Apr 9.

Almaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan; M.A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, 86 Dosmukhamedov St., Almaty, 050012, Kazakhstan. Electronic address:

Lyme borreliosis (LB) is one of the most common vector-borne diseases transmitted by ticks. It is caused by the Borrelia burgdorferi sensu lato (s.l. Read More

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One man, three tick-borne illnesses.

BMJ Case Rep 2021 Apr 16;14(4). Epub 2021 Apr 16.

Department of Internal Medicine, Providence Health and Services Oregon and Southwest Washington, Portland, Oregon, USA.

A 70-year-old man presented to the emergency department with fevers, ankle edema and nausea following a presumed insect bite on his ankle 1 month prior. On examination, he was febrile and had left leg pain with passive range of motion. Laboratory studies revealed anemia, thrombocytopenia, acute kidney injury and elevated aminotransaminases. Read More

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[CME: Musculoskeletal Manifestations of Lyme Disease].

Praxis (Bern 1994) 2021 Apr;110(5):231-236

Innere Medizin, Kantonsspital Graubünden, Chur.

CME: Musculoskeletal Manifestations of Lyme Disease Lyme disease is the most common vector-borne illness in Switzerland and Lyme arthritis the most prevalent manifestation of late-stage Lyme disease. It presents as a monoarthitis or oligoarthritis in large joints, often involving the knee. Such a clinical presentation, together with positive Lyme serologies or polymerase chain reactions from synovial fluid/tissue, is considered diagnostic. Read More

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Passive Tick Surveillance and Detection of Species in Ticks from British Columbia, Canada: 2002-2018.

Vector Borne Zoonotic Dis 2021 Apr 7. Epub 2021 Apr 7.

Communicable Diseases & Immunization Service, BC Centre for Disease Control, Vancouver, Canada.

Lyme disease, caused by (s.l.) complex, is the most common vector-borne disease in North America. Read More

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The prevalence of Borrelia in Ixodes persulcatus in southeastern Kazakhstan.

Ticks Tick Borne Dis 2021 Mar 23;12(4):101716. Epub 2021 Mar 23.

Almaty Branch of the National Center for Biotechnology, Committee of Science, Ministry of Education and Science of the Republic of Kazakhstan, 14 Zhahanger St., Almaty, 050054, Kazakhstan.

Borreliosis is one of the most common vector-borne zoonotic diseases in the world. Limited data are available regarding Borrelia spp. and their genotypes in Kazakhstan. Read More

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Seroepidemiologic Survey of Lyme Disease among Forestry Workers in National Park Offices in South Korea.

Int J Environ Res Public Health 2021 03 12;18(6). Epub 2021 Mar 12.

Department of Preventive Medicine, College of Medicine, Dongguk University, Gyeongju 38066, Korea.

Limited data are available on the current status of Lyme disease in South Korea. The aim of this study was to investigate the seroprevalence and risk factors associated with Lyme disease infection among forestry workers in National Park Offices in South Korea. We enrolled National Park Office forestry workers (NPOFWs) who had worked for ≥1 year. Read More

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Likely Geographic Distributional Shifts among Medically Important Tick Species and Tick-Associated Diseases under Climate Change in North America: A Review.

Insects 2021 Mar 5;12(3). Epub 2021 Mar 5.

Biodiversity Institute, University of Kansas, Lawrence, KS 66045, USA.

Ticks rank high among arthropod vectors in terms of numbers of infectious agents that they transmit to humans, including Lyme disease, Rocky Mountain spotted fever, Colorado tick fever, human monocytic ehrlichiosis, tularemia, and human granulocytic anaplasmosis. Increasing temperature is suspected to affect tick biting rates and pathogen developmental rates, thereby potentially increasing risk for disease incidence. Tick distributions respond to climate change, but how their geographic ranges will shift in future decades and how those shifts may translate into changes in disease incidence remain unclear. Read More

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Tick-Borne Encephalitis Virus Seropositivity among Tick Infested Individuals in Serbia.

Pathogens 2021 Mar 5;10(3). Epub 2021 Mar 5.

Anses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, F-94700 Maisons-Alfort, France.

Tick-borne encephalitis (TBE), caused by the TBE virus (TBEV), is a life-threatening disease with clinical symptoms ranging from non-specific to severe inflammation of the central nervous system. Despite TBE is a notifiable disease in Serbia since 2004, there is no active TBE surveillance program for the serologic or molecular screening of TBEV infection in humans in the country. This prospective cohort study aimed to assess the TBEV exposure among tick-infested individuals in Serbia during the year 2020. Read More

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The Impact of Tick-Borne Diseases on the Bone.

Microorganisms 2021 Mar 23;9(3). Epub 2021 Mar 23.

Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.

Tick-borne infectious diseases can affect many tissues and organs including bone, one of the most multifunctional structures in the human body. There is a scarcity of data regarding the impact of tick-borne pathogens on bone. The aim of this review was to survey existing research literature on this topic. Read More

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Shared Odds of and Rabies Virus Exposure in Serbia.

Pathogens 2021 Mar 28;10(4). Epub 2021 Mar 28.

Anses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, F-94700 Maisons-Alfort, France.

Lyme borreliosis (LB) is the most common tick-borne disease in Serbia and other European countries. Rabies is a fatal zoonosis distributed worldwide and is caused by the rabies virus. Professionals at risk of rabies-including veterinarians, hunters, communal service workers, and forestry workers-overlap with some professions at a higher risk of exposure to tick bites and tick-borne pathogen infections. Read More

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Projecting the potential distribution of ticks in China under climate and land use change.

Int J Parasitol 2021 Mar 31. Epub 2021 Mar 31.

College of Environment Science and Engineering, Huazhong University of Science and Technology, Wuhan 430070, China; UK Centre for Ecology & Hydrology, Wallingford OX10 8BB, UK; Environmental Change Institute, University of Oxford, Oxford OX1 3QY, UK. Electronic address:

Ticks are known as vectors of several pathogens causing various human and animal diseases including Lyme borreliosis, tick-borne encephalitis, and Crimean-Congo hemorrhagic fever. While China is known to have more than 100 tick species well distributed over the country, our knowledge on the likely distribution of ticks in the future remains very limited, which hinders the prevention and control of the risk of tick-borne diseases. In this study, we selected four representative tick species which have different regional distribution foci in mainland China. Read More

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Update on prevalence and distribution pattern of tick-borne diseases among humans in India: a review.

Parasitol Res 2021 May 2;120(5):1523-1539. Epub 2021 Apr 2.

School of Environment and Natural Resources, Doon University, Dehradun, Uttarakhand, 248 012, India.

In the present scenario, tick-borne diseases (TBDs) are well known for their negative impacts on humans as well as animal health in India. The reason lies in their increased incidences due to global warming, environmental and ecological changes, and availability of suitable habitats. On a global basis, they are now considered a serious threat to human as well as livestock health. Read More

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[The state of mental health in people with a diagnosis of neuroborreliosis].

Authors:
Kaja Staszewska

Med Pr 2021 Mar 18. Epub 2021 Mar 18.

Instytut Medycyny Pracy im. prof. J. Nofera / Nofer Institute of Occupational Medicine, Łódź, Poland (Zakład Psychologii Zdrowia i Pracy / Department of Health and Work Psychology).

Background: In recent years, the number of recorded cases of infections causing Lyme borreliosis has been on a steady rise in Poland. A wide spectrum of disorders in the peripheral and central nervous system is observed in the course of such infections. Symptoms which are not clear-cut are reported by approx. Read More

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Public perceptions of Lyme disease and climate change in southern Manitoba, Canada: making a case for strategic decoupling of climate and health messages.

BMC Public Health 2021 Mar 30;21(1):617. Epub 2021 Mar 30.

Prairie Climate Centre, University of Winnipeg, 515 Portage Ave, Winnipeg, Manitoba, R3B 2E9, Canada.

Background: Despite scientific evidence that climate change has profound and far reaching implications for public health, translating this knowledge in a manner that supports citizen engagement, applied decision-making, and behavioural change can be challenging. This is especially true for complex vector-borne zoonotic diseases such as Lyme disease, a tick-borne disease which is increasing in range and impact across Canada and internationally in large part due to climate change. This exploratory research aims to better understand public risk perceptions of climate change and Lyme disease in order to increase engagement and motivate behavioural change. Read More

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Experience and knowledge of Lyme disease: A scoping review of patient-provider communication.

Ticks Tick Borne Dis 2021 Mar 23;12(4):101714. Epub 2021 Mar 23.

Northeast Regional Center for Excellence in Vector-Borne Diseases, 3138 Comstock Hall, Department of Entomology, Cornell University, Ithaca, NY 14853, USA. Electronic address:

There has been limited research on patient-provider communication dynamics regarding Lyme disease (LD) diagnosis and treatment. Evidence suggests communication in the clinical encounter improves when both patient and healthcare provider (HCP) have concordant orientations (or beliefs) on discussed topics, resulting in higher patient satisfaction and care outcomes. The purpose of this scoping review was to characterize and summarize current research findings on patient and provider knowledge and experiences regarding LD - two factors that may influence the orientation of both patients and providers toward LD in the clinical setting. Read More

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Survey on tick distribution and tick-borne pathogens in Daejeon and adjacent areas in South Korea.

Ticks Tick Borne Dis 2021 Mar 15;12(4):101711. Epub 2021 Mar 15.

Daejeon Metropolitan City Institute of Health and Environment, 407 Daehak-ro, Yuseong-gu, Daejeon, 34142, Republic of Korea.

Ticks (Ixodidae, also known as hard ticks) as principal vectors of zoonotic diseases such as severe fever with thrombocytopenia syndrome (SFTS), Lyme borreliosis, relapsing fever, anaplasmosis, ehrlichiosis, babesiosis, coxiellosis (Q fever), and tularemia pose a major public health threat. This study was conducted to identify the distribution profile of ticks and tick-borne pathogens in Daejeon and the adjacent areas in South Korea, where no such epidemiological study has been conducted. From April to October 2019, 16,765 ticks were collected from three genera and four species: Haemaphysalis longicornis (n = 14,949; 89. Read More

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Predicting Lyme Disease From Patients' Peripheral Blood Mononuclear Cells Profiled With RNA-Sequencing.

Front Immunol 2021 8;12:636289. Epub 2021 Mar 8.

Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Although widely prevalent, Lyme disease is still under-diagnosed and misunderstood. Here we followed 73 acute Lyme disease patients and uninfected controls over a period of a year. At each visit, RNA-sequencing was applied to profile patients' peripheral blood mononuclear cells in addition to extensive clinical phenotyping. Read More

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Survey to detect tick-borne encephalitis virus from human-feeding ticks in Hokkaido, Japan.

J Dermatol 2021 Mar 23. Epub 2021 Mar 23.

National Research Center for the Control and Prevention of Infectious Diseases (CCPID, Nagasaki University, Nagasaki, Japan.

A tick infestation is one of the most common arthropod-related skin diseases in Hokkaido, the northernmost island of Japan. Ticks also act as an infectious disease vector for humans. Tick-borne encephalitis (TBE), a highly mortal central nervous system infection caused by TBE virus (TBEV), has sporadically occurred there recently. Read More

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Masting by beech trees predicts the risk of Lyme disease.

Parasit Vectors 2021 Mar 20;14(1):168. Epub 2021 Mar 20.

Laboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.

Background: The incidence of Lyme borreliosis and other tick-borne diseases is increasing in Europe and North America. There is currently much interest in identifying the ecological factors that determine the density of infected ticks as this variable determines the risk of Lyme borreliosis to vertebrate hosts, including humans. Lyme borreliosis is caused by the bacterium Borrelia burgdorferi sensu lato (s. Read More

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43-Year-Old Female With Fever and Bullous Skin Lesion.

Clin Infect Dis 2020 12;71(10):2763-2764

Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

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December 2020

A comprehensive clinical and laboratory evaluation of 224 patients with persistent symptoms attributed to presumed tick-bite exposure.

PLoS One 2021 18;16(3):e0247384. Epub 2021 Mar 18.

Department of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden.

Background: Persistent symptoms attributed to presumed tick-bite exposure constitute an unresolved medical controversy. We evaluated whether Swedish adults who met the criteria for post-treatment Lyme disease syndrome (PTLDS) exhibited characteristics distinguishable from adults who did not, but who displayed similar symptoms and disease course after suspected previous tick-bite infection (TBI).

Methods And Findings: During 2015-2018, 255 patients-referred to the Centre for Vector-borne Infections, Uppsala University Hospital, Sweden with symptoms lasting longer than six months-were recruited. Read More

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