10,523 results match your criteria Tick-Borne Diseases Lyme


Learning to live with ticks? The role of exposure and risk perceptions in protective behaviour against tick-borne diseases.

PLoS One 2018 20;13(6):e0198286. Epub 2018 Jun 20.

Department of Economics, University of Gothenburg, Gothenburg, Sweden.

The purpose of this study is to analyse the role of risk perceptions and exposure for protective behaviour against tick bites and the related diseases Lyme borreliosis (LB) and tick-borne encephalitis (TBE), both of which are growing health concerns. We use data from a national survey in Sweden with respondents in geographical areas with substantial differences in both abundance of ticks and incidence of LB and TBE. We find that the share of respondents who frequently use protective clothing (64%), perform tick checks (63%) or avoid tall grass while in areas with ticks (48%) is relatively high. Read More

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A Community Study of Antibodies among Individuals with Prior Lyme Disease in Endemic Areas.

Healthcare (Basel) 2018 Jun 19;6(2). Epub 2018 Jun 19.

Department of Psychiatry, Lyme and Tick-Borne Diseases Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.

The objective was to examine the prevalence of antibodies among symptomatic individuals with recent and past Lyme disease in endemic communities using standard assays and novel assays employing next-generation antigenic substrates. Single- and two-tiered algorithms included different anti- ELISAs and immunoblots. Antibody prevalence was examined in sera from 32 individuals with recent erythema migrans (EM), 335 individuals with persistent symptoms following treatment for Lyme disease (PTLS), and 41 community controls without a history of Lyme disease. Read More

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Immune Responses Against Lyme Disease Pathogens.

Front Cell Infect Microbiol 2018 29;8:176. Epub 2018 May 29.

Department of Veterinary Medicine and Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD, United States.

Although and other related tick species are considered prolific vectors for a number of important human diseases, many aspects of their biology, microbial interactions, and immunity are largely unknown; in particular, how these ancient vectors recognize invading pathogens like and influence their persistence. The analysis of the genome and a limited set of transcriptomic data have established that ticks encode many components of classical immune pathways; yet at the same time, they lack many key orthologs of these recognition networks. Therefore, whether a given immune pathway is active in ticks and how precisely they exert its microbicidal functions are only incompletely delineated. Read More

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Higher sensitivity of Line Borrelia IgG Immunoblot Kit compared with Standard Lyme IgG Immunoblot Following CDC Testing Criteria.

J Clin Microbiol 2018 Jun 6. Epub 2018 Jun 6.

Cadham Provincial Laboratory, Winnipeg, MB, Canada.

Lyme disease (LD), caused by , is the most common tick-borne disease in the United States (US) and Canada.…. Read More

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June 2018
2 Reads

Integrated control of juvenile Ixodes scapularis parasitizing Peromyscus leucopus in residential settings in Connecticut, United States.

Ticks Tick Borne Dis 2018 May 28. Epub 2018 May 28.

Center for Vector Biology & Zoonotic Diseases, The Connecticut Agricultural Experiment Station, P.O. Box 1106, 123 Huntington Street, New Haven, CT 06504, USA. Electronic address:

Lyme disease continues to be the most common vector-borne disease in the United States with an estimated 330,000 human cases annually. In the eastern United States, the blacklegged tick, Ixodes scapularis, is the primary vector of the Lyme disease spirochete, Borrelia burgdorferi, and the white-footed mouse, Peromyscus leucopus, is a primary reservoir host. In four residential neighborhoods in Connecticut over three years, we tested the effectiveness of different low-toxicity integrated tick management approaches to control larval and nymphal I. Read More

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May 2018
3 Reads

Blood cell disruption to significantly improve the Borrelia PCR detection sensitivity in borreliosis in humans.

Med Hypotheses 2018 Jul 15;116:1-3. Epub 2018 Apr 15.

Infectious Diseases Unit, University Hospital Raymond Poincaré, APHP, Versailles Saint Quentin University, Garches, France. Electronic address:

Lyme disease is the most frequently reported zoonotic tick-borne disease worldwide, and the number of infected humans is increasing. Lyme disease (or Lyme borreliosis) is an affection caused by the spirochete Borrelia burgdorferi, sensu lato. Lyme disease is also reported as a variety of misleading clinical symptomatologies. Read More

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July 2018
1 Read

Serologic Evidence of Tick-Borne Encephalitis Virus Infection in a Patient with Suspected Lyme Disease in Japan.

Am J Trop Med Hyg 2018 May 29. Epub 2018 May 29.

Department of Bacteriology-I, National Institute of Infectious Diseases, Tokyo, Japan.

Tick-borne encephalitis (TBE) is widely prevalent on the Eurasian continent, including Japan, but four cases of TBE have been reported in Japan. To inspect unconfirmed TBE cases in Japan, we conducted a retrospective seroepidemiological study of a total of 158 samples from 81 meningoencephalitis patients suspected as Lyme disease. Two serum samples from one patient showed neutralizing antibodies against TBE virus. Read More

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May 2018
1 Read

Forecasting next season's Ixodes ricinus nymphal density: the example of southern Germany 2018.

Exp Appl Acarol 2018 May 30. Epub 2018 May 30.

Institute for Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210, Vienna, Austria.

The castor bean tick, Ixodes ricinus (L.) (Ixodida: Ixodidae), is the principal vector of pathogens causing tick-borne encephalitis or Lyme borreliosis in Europe. It is therefore of general interest to make an estimate of the density of I. Read More

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May 2018
1 Read

Tick bites and tick-transmitted diseases.

Vet Rec 2018 05;182(21):609

The Moredun Research, Institute Bush Loan, Penicuik EH26 0PZ.

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May 2018
1 Read

Update on Tick-Borne Bacterial Diseases in Travelers.

Curr Infect Dis Rep 2018 May 22;20(7):17. Epub 2018 May 22.

Aix Marseille University, IRD, AP-HM, SSA, Vecteurs-Infections Tropicales et Méditerranéennes (VITROME), IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.

Purpose Of Review: Ticks are the second most important vectors of infectious diseases after mosquitoes worldwide. The growth of international tourism including in rural and remote places increasingly exposes travelers to tick bite. Our aim was to review the main tick-borne infectious diseases reported in travelers in the past 5 years. Read More

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May 2018
1 Read

Tick abundance, pathogen prevalence, and disease incidence in two contrasting regions at the northern distribution range of Europe.

Parasit Vectors 2018 05 22;11(1):309. Epub 2018 May 22.

Centre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, P.O. Box 1066 Blindern, NO-0316, Oslo, Norway.

Background: Emergence of tick-borne diseases is impacting humans and livestock across the Northern Hemisphere. There are, however, large regional variations in number of cases of tick-borne diseases. Some areas have surprisingly few cases of disease compared to other regions. Read More

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May 2018
3 Reads

Molecular identification of tick-borne pathogens in asymptomatic individuals with human immunodeficiency virus type 1 (HIV-1) infection: a retrospective study.

BMC Infect Dis 2018 May 18;18(1):227. Epub 2018 May 18.

Department of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 3C Pawińskiego Street, 02-106, Warsaw, Poland.

Background: The studies on the occurrence and diversity of tick-borne infections in HIV-infected individuals have been few, and the subject has been relatively neglected when compared with other common infections associated with HIV. In HIV-positive patients in whom a serological diagnostics is complicated due to reduced positive predictive value, a method where the microorganism is detected directly is of great value. Therefore, we performed a molecular study to ascertain the prevalence and incidence of tick-borne infections in HIV-infected persons in Poland, an endemic area for Ixodes ricinus ticks. Read More

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May 2018
4 Reads

Shifts in Borrelia burgdorferi (s.l.) geno-species infections in Ixodes ricinus over a 10-year surveillance period in the city of Hanover (Germany) and Borrelia miyamotoi-specific Reverse Line Blot detection.

Parasit Vectors 2018 05 18;11(1):304. Epub 2018 May 18.

Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559, Hanover, Germany.

Background: Lyme borreliosis caused by spirochetes of the Borrelia burgdorferi (sensu lato) complex is still the most common tick-borne disease in Europe, posing a considerable threat to public health. The predominant vector in Europe is the widespread hard tick Ixodes ricinus, which also transmits the relapsing fever spirochete B. miyamotoi as well as pathogenic Rickettsiales (Anaplasma phagocytophilum, Rickettsia spp. Read More

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May 2018
2 Reads

Human Babesiosis Caused by Has Widespread Distribution across Canada.

Healthcare (Basel) 2018 May 17;6(2). Epub 2018 May 17.

International Lyme and Associated Diseases Society, Bethesda, MD 20827, USA.

Human babesiosis caused by is an emerging infectious disease in Canada. This malaria-like illness is brought about by a protozoan parasite infecting red blood cells. Currently, controversy surrounds which tick species are vectors of Since the availability of a serological or molecular test in Canada for has been limited, we conducted a seven-year surveillance study (2011⁻2017) to ascertain the occurrence and geographic distribution of infection country-wide. Read More

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May 2018
2 Reads

Surveillance for Lyme disease in Canada: 2009-2015.

Can Commun Dis Rep 2017 Oct 5;43(10):194-199. Epub 2017 Oct 5.

Centre for Food-borne, Environmental and Zoonotic Infectious Diseases, Public Health Agency of Canada, Saint-Hyacinthe, QC.

Objective: To summarize seven years of surveillance data for Lyme disease cases reported in Canada from 2009 to 2015.

Methods: We describe the incidence over time, seasonal and geographic distribution, demographic and clinical characteristics of reported Lyme disease cases. Logistic regression was used to explore differences between age groups, sex and year to better understand potential demographic risk factors for the occurrence of Lyme disease. Read More

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October 2017
1 Read

What's eating you? Ixodes tick and related diseases, part 2: diagnosis and treatment of regional tick-borne diseases.

Cutis 2018 Apr;101(4):266;268;305

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.

The tick is an important arthropod vector in the transmission of human disease. Although Lyme disease is the most prevalent zoonosis transmitted by Ixodes ticks, other less common diseases may be encountered, including human granulocytic anaplasmosis, babesiosis, Powassan virus infection, tick-borne encephalitis, disease, and tick paralysis. In part 2 of this review, disease presentation, diagnosis, and treatment of these less commonly encountered tick-borne diseases are discussed. Read More

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April 2018
2 Reads

Efficient detection of symptomatic and asymptomatic patient samples for Babesia microti and Borrelia burgdorferi infection by multiplex qPCR.

PLoS One 2018 10;13(5):e0196748. Epub 2018 May 10.

Department of Microbiology, Biochemistry and molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey, United States of America.

Background: Tick-borne infections have been increasing steadily over the years, with co-infections with Borrelia burgdorferi and Babesia microti/divergens emerging as a serious health problem. B. burgdorferi is a spirochetal bacterium that causes Lyme disease while protozoan pathogens belonging to Babesia species are responsible for babesiosis. Read More

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May 2018
4 Reads

Influence of climatic factors on Ixodes ricinus nymph abundance and phenology over a long-term monthly observation in Switzerland (2000-2014).

Parasit Vectors 2018 05 8;11(1):289. Epub 2018 May 8.

Institute of Biology, University of Neuchâtel, Emile Argand 11, 2000, Neuchâtel, Switzerland.

Background: One of the major public health challenges in the field of communicable diseases consists of being able to predict where and when a population is at risk of being infected by a pathogen. In the case of vector-borne diseases, such predictions often require strong ecological knowledge of the vector life-cycle and the environmental conditions promoting or preventing its establishment and maintenance. In this study, we analyse how climatic factors influence the abundance and phenology of the Lyme borreliosis vector Ixodes ricinus in a Swiss temperate forest, based on a long-term monthly observation over a period of 15 years (2000 and 2014). Read More

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Tick-borne disease risk in a forest food web.

Ecology 2018 May 8. Epub 2018 May 8.

Cary Institute of Ecosystem Studies, Millbrook, New York, 12545, USA.

Changes to the community ecology of hosts for zoonotic pathogens, particularly rodents, are likely to influence the emergence and prevalence of zoonotic diseases worldwide. However, the complex interactions between abiotic factors, pathogens, vectors, hosts, and both food resources and predators of hosts are difficult to disentangle. Here we (1) use 19 yr of data from six large field plots in southeastern New York to compare the effects of hypothesized drivers of interannual variation in Lyme disease risk, including the abundance of acorns, rodents, and deer, as well as a series of climate variables; and (2) employ landscape epidemiology to explore how variation in predator community structure and forest cover influences spatial variation in the infection prevalence of ticks for the Lyme disease bacterium, Borrelia burgdorferi, and two other important tick-borne pathogens, Anaplasma phagocytophilum and Babesia microti. Read More

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May 2018
2 Reads

Vital Signs: Trends in Reported Vectorborne Disease Cases - United States and Territories, 2004-2016.

MMWR Morb Mortal Wkly Rep 2018 May 4;67(17):496-501. Epub 2018 May 4.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Fort Collins, Colorado.

Introduction: Vectorborne diseases are major causes of death and illness worldwide. In the United States, the most common vectorborne pathogens are transmitted by ticks or mosquitoes, including those causing Lyme disease; Rocky Mountain spotted fever; and West Nile, dengue, and Zika virus diseases. This report examines trends in occurrence of nationally reportable vectorborne diseases during 2004-2016. Read More

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May 2018
7 Reads

Effects of a zoonotic pathogen, , on the behavior of a key reservoir host.

Ecol Evol 2018 Apr 26;8(8):4074-4083. Epub 2018 Mar 26.

Bard College Annandale-on-Hudson NY USA.

Most emerging infectious diseases of humans are transmitted to humans from other animals. The transmission of these "zoonotic" pathogens is affected by the abundance and behavior of their wildlife hosts. However, the effects of infection with zoonotic pathogens on behavior of wildlife hosts, particularly those that might propagate through ecological communities, are not well understood. Read More

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April 2018
2 Reads

What's eating you? Ixodes tick and related diseases, part 1: life cycle, local reactions, and lyme disease.

Cutis 2018 Mar;101(3):187-190

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.

The tick is an important arthropod vector in the transmission of human disease. This 3-part review highlights the biology of the tick and manifestations of related diseases. Part 1 addresses the tick biology and life cycle; local reactions; and Lyme disease, the most prevalent of associated diseases. Read More

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March 2018
1 Read

Low probability of a dilution effect for Lyme borreliosis in Belgian forests.

Ticks Tick Borne Dis 2018 Apr 22. Epub 2018 Apr 22.

Forest & Nature Lab, Department of Environment, Ghent University, Geraardsbergsesteenweg 267, 9090, Melle-Gontrode, Belgium. Electronic address:

An increasing number of studies have investigated the consequences of biodiversity loss for the occurrence of vector-borne diseases such as Lyme borreliosis, the most common tick-borne disease in the northern hemisphere. As host species differ in their ability to transmit the Lyme borreliosis bacteria Borrelia burgdorferi s.l. Read More

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Seroprevalence of Borrelia burgdorferi in Belgian forestry workers and associated risk factors.

Parasit Vectors 2018 05 2;11(1):277. Epub 2018 May 2.

Earth and Life Institute (ELI), Georges Lemaitre Center for Earth and Climate Research, Université catholique de Louvain (UCL), Louvain-la-Neuve, Belgique.

Background: As forest is the preferred environment for ticks, forestry workers are exposed to tick bites and tick-borne diseases. We assessed the seroprevalence of anti-Borrelia burgdorferi (Bb) antibodies and investigated, using an integrated landscape approach, the individual and environmental factors associated with the seroprevalence of Bb in Belgian forestry workers, a high-risk group in Belgium.

Methods: A group of 310 Belgian forest workers was examined to assess the seroprevalence of anti-Borrelia IgG antibodies. Read More

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May 2018
1 Read

CXCL13 concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other neurological disorders determined by Luminex and ELISA.

Ticks Tick Borne Dis 2018 Apr 20. Epub 2018 Apr 20.

Institute for Hygiene and Applied Immunology, Medical University of Vienna, Austria.

The aims of the study were to determine and compare the concentration of CXCL13 in cerebrospinal fluid (CSF) of patients with Lyme neuroborreliosis (LNB) and various other neurological disorders applying a Luminex based assay and ELISA, and to find factors associated with CXCL13 concentration. CSF samples obtained from four clinically well-defined groups of patients (proven LNB, suspected LNB, tick-borne encephalitis (TBE), and aseptic meningitis/meningoencephalitis other than TBE) - 25 samples per group - were analyzed. The performance of the Luminex recomBead CXCL13 assay (Microgen, Neuried, Germany) and ELISA (Euroimmun, Lübeck, Germany) was assessed by receiver operating characteristics. Read More

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Modeling Climate Suitability of the Western Blacklegged Tick in California.

J Med Entomol 2018 Apr 25. Epub 2018 Apr 25.

Department of Environmental Science, Policy and Management, University of California, Berkeley, CA.

Ixodes pacificus Cooley & Kohls (Acari: Ixodidae), the primary vector of Lyme disease spirochetes to humans in the far-western United States, is broadly distributed across Pacific Coast states, but its distribution is not uniform within this large, ecologically diverse region. To identify areas of suitable habitat, we assembled records of locations throughout California where two or more I. pacificus were collected from vegetation from 1980 to 2014. Read More

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April 2018
4 Reads

Relapsing Fevers: Neglected Tick-Borne Diseases.

Front Cell Infect Microbiol 2018 4;8:98. Epub 2018 Apr 4.

Early Bacterial Virulence: Borrelia Group, Université de Strasbourg, Facultés de Médecine et de Pharmacie, CHRU Strasbourg, Fédération de Médecine Translationnelle de Strasbourg, VBB EA 7290, Strasbourg, France.

Relapsing fever still remains a neglected disease and little is known on its reservoir, tick vector and physiopathology in the vertebrate host. The disease occurs in temperate as well as tropical countries. Relapsing fever borreliae are spirochaetes, members of the family which also contain Lyme disease spirochaetes. Read More

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April 2018
1 Read

Identification of Lyme borreliae proteins promoting vertebrate host blood-specific spirochete survival in Ixodes scapularis nymphs using artificial feeding chambers.

Ticks Tick Borne Dis 2018 Apr 4. Epub 2018 Apr 4.

Department of Biomedical Sciences, State University of New York at Albany, NY, USA; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA. Electronic address:

Lyme borreliosis, the most common vector-borne illness in Europe and the United States, is caused by spirochetes of the Borrelia burgdorferi sensu lato complex and transmitted by Ixodes ticks. In humans, the spirochetes disseminate from the tick bite site to multiple tissues, leading to serious clinical manifestations. The ability of spirochetes to survive in ticks during blood feeding is thought to be essential for Lyme borreliae to be transmitted to different vertebrate hosts. Read More

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Infection history of the blood-meal host dictates pathogenic potential of the Lyme disease spirochete within the feeding tick vector.

PLoS Pathog 2018 04 5;14(4):e1006959. Epub 2018 Apr 5.

Laboratory of Bacteriology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT United States of America.

Lyme disease in humans is caused by several genospecies of the Borrelia burgdorferi sensu lato (s.l.) complex of spirochetal bacteria, including B. Read More

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Prevalence of Borrelia burgdorferi in ticks removed from skin of people and circumstances of being bitten - research from the area of Poland, 2012-2014.

Ann Agric Environ Med 2018 Mar 11;25(1):31-35. Epub 2017 Feb 11.

Institute of Health, State Higher Vocational School of Technology and Economic in Jaroslaw, Jaroslaw, Poland.

Introduction: During feeding, the tick sucks blood from the host along with the pathogens that are in the blood, simultaneously exchanging its own pathogens with the host. Humans can also be a host. It is important to understand the most typical circumstances in which people might become infected with Borrelia burgdorferi. Read More

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March 2018
1 Read

Detection of Borrelia in Ixodes scapularis ticks by silver stain, immunohistochemical and direct immunofluorescent methods.

J Cutan Pathol 2018 Jul 30;45(7):473-477. Epub 2018 Apr 30.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

Background: Lyme disease (LD) is one of the most common tick-borne diseases caused by several Borrelia species of spirochetes. Ixodes scapularis is responsible for the transmission of LD in the northeastern United States. The rate of infection varies with the duration of tick attachment to the host; however, this information may be unknown. Read More

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July 2018
3 Reads

High-Resolution Ecological Niche Modeling of Ixodes scapularis Ticks Based on Passive Surveillance Data at the Northern Frontier of Lyme Disease Emergence in North America.

Vector Borne Zoonotic Dis 2018 05 22;18(5):235-242. Epub 2018 Mar 22.

2 School of Epidemiology and Public Health, University of Ottawa , Ottawa, Canada .

Background: Lyme disease (LD) is a bacterial infection transmitted by the black-legged tick (Ixodes scapularis) in eastern North America. It is an emerging disease in Canada due to the expanding range of its tick vector. Environmental risk maps for LD, based on the distribution of the black-legged tick, have focused on coarse determinants such as climate. Read More

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Crimean-Congo Hemorrhagic Fever Virus and sensu lato in Ticks from Kosovo and Albania.

Front Vet Sci 2018 6;5:38. Epub 2018 Mar 6.

Department of Pathobiology, Institute of Parasitology, University of Veterinary Medicine Vienna, Vienna, Austria.

Tick-borne diseases pose a serious threat to human health in South-Eastern Europe, including Kosovo. While Crimean-Congo hemorrhagic fever (CCHF) is a well-known emerging infection in this area, there are no accurate data on Lyme borreliosis and tick-borne encephalitis (TBE). Therefore, we sampled and tested 795 ticks. Read More

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Assessment of HMGB-1 concentration in tick-borne encephalitis and neuroborreliosis.

Int J Infect Dis 2018 May 17;70:131-136. Epub 2018 Mar 17.

Department of Infectious Diseases and Neuroinfections, Medical University in Białystok, Białystok, Poland.

Background: The aim of this study was to determine the concentration of HMGB-1 (high mobility group box 1) in the serum and cerebrospinal fluid (CSF) of patients suffering from tick-borne encephalitis (TBE) and neuroborreliosis (NB). Focus was placed on HMGB-1 measurement in the CSF or serum in order to establish whether this could help to differentiate between NB and TBE.

Methods: Eighty patients with meningitis and meningoencephalitis were enrolled in the study. Read More

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May 2018
2 Reads

The Tick Project: Testing Environmental Methods of Preventing Tick-borne Diseases.

Trends Parasitol 2018 Jun 13;34(6):447-450. Epub 2018 Mar 13.

Cary Institute of Ecosystem Studies, Millbrook, NY 12545, USA.

Prevention of tick-borne diseases in humans is challenging. To date, no prevention strategies have been shown to be consistently effective. Here, we describe the design of a new large-scale study, involving hundreds of households in Dutchess County, New York, testing whether environmental interventions, applied intensively and over 4 years, can prevent human cases. Read More

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CE: Lyme Disease: Diagnosis, Treatment, and Prevention.

Am J Nurs 2018 Apr;118(4):38-45

Susan Kane Patton is an assistant professor in the Department of Nursing at the University of Arkansas in Fayetteville. Bailey Phillips is an RN in the Department of Neurology and Neurosurgery at Le Bonheur Children's Hospital in Memphis, TN. Contact author: Susan Kane Patton, The authors and planners have disclosed no potential conflicts of interest, financial or otherwise.

: Lyme disease is recognized as the most common vector-borne disease in the United States. Surveillance data indicate both increasing numbers of Lyme disease cases and geographic expansion of areas where the causative spirochete, Borrelia burgdorferi, can be found. With prompt diagnosis and appropriate treatment in the acute stage, most patients will recover fully. Read More

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April 2018
1 Read

Otolaryngological symptoms in patients treated for tick-borne diseases.

Otolaryngol Pol 2018 Feb;72(1):30-34

Otolaryngology Clinic, Jagiellonian University Collegium Medicu, Krakow, Poland; Head Department: Jacek Składzień, PH, MD.

infections are borreliosis (Lyme disease) and tick-borne encephalitis (TBE). Lately there is growing incidence of Bartonella, Babesia, Anaplasma and Brucella co-infections. The similarity between the symptoms of tick-borne diseases and other pathologies causes serious diagnostic issues. Read More

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February 2018
10 Reads

Control of Lyme borreliosis and other Ixodes ricinus-borne diseases.

Parasit Vectors 2018 03 6;11(1):145. Epub 2018 Mar 6.

Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.

Lyme borreliosis (LB) and other Ixodes ricinus-borne diseases (TBDs) are diseases that emerge from interactions of humans and domestic animals with infected ticks in nature. Nature, environmental and health policies at (inter)national and local levels affect the risk, disease burden and costs of TBDs. Knowledge on ticks, their pathogens and the diseases they cause have been increasing, and resulted in the discovery of a diversity of control options, which often are not highly effective on their own. Read More

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Comparison of phenoxymethylpenicillin, amoxicillin, and doxycycline for erythema migrans in general practice. A randomized controlled trial with a 1-year follow-up.

Clin Microbiol Infect 2018 Mar 2. Epub 2018 Mar 2.

Antibiotic Centre for Primary Care (ASP), Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.

Objectives: To compare the three most commonly used antibiotics for erythema migrans (EM) in Norwegian primary care.

Methods: A randomized, parallel, controlled trial was carried out. Treatments were open to the patients, but blinded for the GPs and investigators. Read More

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Widespread distribution of ticks and selected tick-borne pathogens in Kentucky (USA).

Ticks Tick Borne Dis 2018 Mar 2;9(3):738-741. Epub 2018 Mar 2.

Warnell School of Forestry and Natural Resources, University of Georgia, Athens, GA 30602, USA; Southeastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA. Electronic address:

The geographical distribution of Ixodes scapularis and Amblyomma maculatum ticks is poorly understood in Kentucky. We conducted a convenience survey of wildlife species (white-tailed deer (Odocoileus virginianus), elk (Cervus canadensis) and black bears (Ursus americanus)) for ticks from October 2015 to January 2017. We detected four tick species including Amblyomma americanum, Dermacentor albipictus, I. Read More

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March 2018
3 Reads

Citizen Science and Community Engagement in Tick Surveillance-A Canadian Case Study.

Healthcare (Basel) 2018 Mar 2;6(1). Epub 2018 Mar 2.

Department. Biology, Mount Allison University, Sackville, NB E4L 1G7, Canada.

Lyme disease is the most common tick-borne disease in North America and Europe, and on-going surveillance is required to monitor the spread of the tick vectors as their populations expand under the influence of climate change. Active surveillance involves teams of researchers collecting ticks from field locations with the potential to be sites of establishing tick populations. This process is labor- and time-intensive, limiting the number of sites monitored and the frequency of monitoring. Read More

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A field-based indicator for determining the likelihood of Ixodes scapularis establishment at sites in Ontario, Canada.

PLoS One 2018 27;13(2):e0193524. Epub 2018 Feb 27.

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

The emergence of the vector Ixodes scapularis in Ontario, Canada poses a significant public health risk. Both passive and active surveillance approaches have been employed by public health professionals (i.e. Read More

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May 2018
2 Reads

The Complement Binding and Inhibitory Protein CbiA of Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen).

Front Cell Infect Microbiol 2018 2;8:23. Epub 2018 Feb 2.

Institute of Medical Microbiology and Infection Control, University Hospital of Frankfurt, Frankfurt, Germany.

The emerging relapsing fever spirochete (.) is transmitted by ixodid ticks and causes the so-called hard tick-borne relapsing fever or disease (BMD). More recently, we identified a surface-exposed molecule, CbiA exhibiting complement binding and inhibitory capacity and rendering spirochetes resistant to complement-mediated lysis. Read More

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February 2018
2 Reads

A multiplex serologic platform for diagnosis of tick-borne diseases.

Sci Rep 2018 02 16;8(1):3158. Epub 2018 Feb 16.

Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.

Tick-borne diseases are the most common vector-borne diseases in the United States, with serology being the primary method of diagnosis. We developed the first multiplex, array-based assay for serodiagnosis of tick-borne diseases called the TBD-Serochip. The TBD-Serochip was designed to discriminate antibody responses to 8 major tick-borne pathogens present in the United States, including Anaplasma phagocytophilum, Babesia microti, Borrelia burgdorferi, Borrelia miyamotoi, Ehrlichia chaffeensis, Rickettsia rickettsii, Heartland virus and Powassan virus. Read More

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February 2018
1 Read

Data-driven predictions and novel hypotheses about zoonotic tick vectors from the genus Ixodes.

BMC Ecol 2018 Feb 15;18(1). Epub 2018 Feb 15.

Cary Institute of Ecosystem Studies, Box AB, Millbrook, NY, 12545, USA.

Background: With the resurgence of tick-borne diseases such as Lyme disease and the emergence of new tick-borne pathogens such as Powassan virus, understanding what distinguishes vectors from non-vectors, and predicting undiscovered tick vectors is a crucial step towards mitigating disease risk in humans. We aimed to identify intrinsic traits that predict which Ixodes tick species are confirmed or strongly suspected to be vectors of zoonotic pathogens.

Methods: We focused on the well-studied tick genus Ixodes from which many species are known to transmit zoonotic diseases to humans. Read More

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February 2018
3 Reads

Lyme disease surveillance in the United States: Looking for ways to cut the Gordian knot.

Zoonoses Public Health 2018 03;65(2):227-229

Division of Vector-borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.

Current surveillance methods have been useful to document geographic expansion of Lyme disease in the United States and to monitor the increasing incidence of this major public health problem. Nevertheless, these approaches are resource-intensive, generate results that are difficult to compare across jurisdictions, and measure less than the total burden of disease. By adopting more efficient methods, resources could be diverted instead to education of at-risk populations and new approaches to prevention. Read More

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March 2018
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Knowledge and preventive behaviors towards tick-borne diseases in Delaware.

Ticks Tick Borne Dis 2018 Mar 3;9(3):615-622. Epub 2018 Feb 3.

Delaware State University, Student Research Team, USA.

Delaware is among the top 10 states in the United States with the highest incidence for Lyme disease. The Delaware Division of Public Health (DPH) therefore has been working diligently to prevent and control tick-borne diseases through a variety of interventions including awareness campaigns and educational programs. To assess if tick-borne disease related information is reaching Delawareans through these programs, DPH in collaboration with Delaware State University administered an anonymous survey to 1755 participants in all three of Delaware counties during May 2017. Read More

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March 2018
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Lyme disease in Poland in 2015

Przegl Epidemiol 2017 ;71(4):513-517

National Institute of Public Health –National Institute of Hygiene in Warsaw Department of Epidemiology

Introduction: Lyme disease is the most common tick-borne disease in Poland. Borrelia burgdorferi spirochete can occur in the whole country, which, according to ECDC, should be considered as an endemic area. Borrelia strains are transmitted to humans and certain other animals by Ixodes (1). Read More

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January 2017
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Exploring an alternative approach to Lyme disease surveillance in Maryland.

Zoonoses Public Health 2018 03 6;65(2):254-259. Epub 2018 Feb 6.

Emerging Infections Program, Maryland Department of Health, Baltimore, MD, USA.

In Maryland, Lyme disease (LD) is a reportable disease and all laboratories and healthcare providers are required to report to the local health department. Given the volume of LD reports and effort required for investigation, surveillance for LD is burdensome and subject to underreporting. We explored the utility of International Classification of Diseases, 9th Revision, Clinical Modification (administrative) codes for use with LD surveillance. Read More

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March 2018
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Transient influence of blood meal and natural environment on blacklegged tick bacterial communities.

Ticks Tick Borne Dis 2018 Mar 31;9(3):563-572. Epub 2018 Jan 31.

Department of Biological Sciences, Fordham University, Bronx, NY, USA; Department of Epidemiology and Biostatistics, School of Public Health, SUNY Downstate Medical Center, Brooklyn, NY, USA. Electronic address:

Blacklegged ticks (Ixodes scapularis) spend the majority of their life cycle off host, typically in woodland habitat, but require a blood meal at each of three life stages (larva, nymph, adult) to reach maturity and reproduce. Blood feeding usually lasts for several days each time and as blood is imbibed, a range of known pathogens from the host may also be acquired. Using next generation sequencing of 16S rRNA gene amplicons, we examined the influence of host blood meal on the internal bacterial community within nymphal blacklegged ticks across host-seeking, feeding, blood meal digestion, and after molting into the adult stage. Read More

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March 2018
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