418 results match your criteria Tick-Borne Diseases Introduction


Evaluation of NSE and S100B in patients with tick-borne encephalitis.

Brain Behav 2018 Nov 22:e01160. Epub 2018 Nov 22.

Department of Infectious Diseases and Neuroinfections, Medical University of Białystok, Białystok, Poland.

Introduction: The aim of this study was the assessment of neuron-specific enolase (NSE) and S-100 concentration in serum and cerebrospinal fluid (CSF) in patients with different clinical forms of tick-borne encephalitis (TBE).

Material And Methods: The serum and CFS concentrations of S100B and NSE of 43 patients with TBE were measured with ELISA method using commercial kits: NSE and S100B Elisa Kit (DRG, Germany). Subjects were divided into: Group I-patients with meningoencephalitis (n = 17) and Group II-patients with meningitis (n = 26). Read More

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http://dx.doi.org/10.1002/brb3.1160DOI Listing
November 2018
4 Reads

The Many Faces of a Dynamic Virion: Implications of Viral Breathing on Flavivirus Biology and Immunogenicity.

Annu Rev Virol 2018 Sep;5(1):185-207

Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA; email: ,

Flaviviruses are arthropod-borne RNA viruses that are a significant threat to global health due to their widespread distribution, ability to cause severe disease in humans, and capacity for explosive spread following introduction into new regions. Members of this genus include dengue, tick-borne encephalitis, yellow fever, and Zika viruses. Vaccination has been a highly successful means to control flaviviruses, and neutralizing antibodies are an important component of a protective immune response. Read More

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https://www.annualreviews.org/doi/10.1146/annurev-virology-0
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http://dx.doi.org/10.1146/annurev-virology-092917-043300DOI Listing
September 2018
11 Reads

Active surveillance of African swine fever in domestic swine herds in Georgia, 2014.

Rev Sci Tech 2017 Dec;36(3):879-887

Since its introduction to the Republic of Georgia in 2007, African swine fever virus (ASFV) has spread across the Caucasus region, the Russian Federation, and some Eastern European countries. It is assumed that large populations of naïve, domestic, free-ranging and wild pigs are vital to the transmission of the disease. Since its epidemic emergence in the region in 2007, ASFV has continued to circulate, which suggests that an endemic cycle has been established and is maintained by contact between free-ranging domestic pigs, wild pigs, and possibly native Ornithodoros ticks, the most likely reservoirs for the virus. Read More

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http://dx.doi.org/10.20506/rst.36.3.2721DOI Listing
December 2017

Interactomics and tick vaccine development: new directions for the control of tick-borne diseases.

Expert Rev Proteomics 2018 Aug 3;15(8):627-635. Epub 2018 Aug 3.

a SaBio. Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM , Ciudad Real , Spain.

Introduction: Ticks are obligate hematophagous arthropod ectoparasites that transmit pathogens responsible for a growing number of tick-borne diseases (TBDs) throughout the world. Vaccines have been shown to be the most efficient, cost-effective, and environmentally friendly approach for the control of ticks and the prevention of TBDs. Although at its infancy, interactomics has shown the possibilities that the knowledge of the interactome offers in understanding tick biology and the molecular mechanisms involved in pathogen infection and transmission. Read More

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http://dx.doi.org/10.1080/14789450.2018.1506701DOI Listing
August 2018
3 Reads

Viral metagenomics, genetic and evolutionary characteristics of Crimean-Congo hemorrhagic fever orthonairovirus in humans, Kosovo.

Infect Genet Evol 2018 Nov 11;65:6-11. Epub 2018 Jul 11.

Department of Arbovirology, Bernhard Nocht Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Hemorrhagic Fever Reference and Research, Hamburg, Germany; German Centre for Infection Research (DZIF), Hamburg, Germany.

Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV) is a tick-borne virus which causes severe disease in humans with fatality cases up to 30%. We investigated the genetic and evolutionary characteristics of CCHFV in Kosovo, in particular in humans and found that different virus variants of genotype V circulate, with Turkey as a possible origin for the progenitor of southern European CCHF outbreaks. Phylogenetic analyses also revealed a single introduction event and in situ evolution of CCHFV in this country. Read More

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http://dx.doi.org/10.1016/j.meegid.2018.07.010DOI Listing
November 2018
6 Reads

Molecular Characterization and Phylogenetic Analysis of Theileria spp. and Babesia spp. Isolated from Various Ticks in Southeastern and Northwestern Regions of Iran.

Vector Borne Zoonotic Dis 2018 11 9;18(11):595-600. Epub 2018 Jul 9.

1 Department of Medical Entomology and Vector Control, School of Public Health , Tehran, Iran .

Introduction: Piroplasms are hemoprotozoa comprising heterogeneous tick-borne parasites, which are differentiated into three genera, namely Babesia, Theileria, and Cytauxzoon. The aim of this study was to determine the prevalence, molecular identification, and phylogenetic relationship of both Theileria spp. and Babesia spp. Read More

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http://dx.doi.org/10.1089/vbz.2018.2271DOI Listing
November 2018
4 Reads

High throughput discovery and characterization of tick and pathogen vaccine protective antigens using vaccinomics with intelligent Big Data analytic techniques.

Expert Rev Vaccines 2018 Jul 12;17(7):569-576. Epub 2018 Jul 12.

d Technologies and Information Systems Institute UCLM , Ciudad Real , Spain.

Introduction: The incidence of tick-borne diseases (TBDs) is growing worldwide, and vaccines appear as the most effective and environmentally sound intervention for the prevention and control of TBDs. Areas covered: The vaccinomics approach combines omics technologies and bioinformatics for the characterization of tick-host-pathogen molecular interactions and the development of next-generation vaccines. The two main challenges of the vaccinomics approach are the integration and analysis of omics datasets, and the development of screening platforms for the identification of candidate protective antigens. Read More

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http://dx.doi.org/10.1080/14760584.2018.1493928DOI Listing
July 2018
11 Reads

Pilot study of Ixodes ricinus ticks preference for human ABO blood groups using a simple in vitro method.

Ann Agric Environ Med 2018 Jun 21;25(2):326-328. Epub 2018 Mar 21.

Department of Animal Physiology and Immunology, Faculty of Science, Masaryk University, Brno, Czech Republic.

Introduction And Objectives: The existence of a blood group preference for ticks is a problem widely discussed among the lay public but often neglected by the scientific community. The Ixodes ricinus tick transmits serious zoonotic diseases such as Lyme borreliosis, tick encephalitis, or anaplasmosis. The preventive strategies include vaccination (if available) and individual measures including the use of repellents and avoidance of risk areas. Read More

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http://dx.doi.org/10.26444/aaem/85167DOI Listing
June 2018
1 Read

Tick distribution along animal tracks: implication for preventative medicine.

Ann Agric Environ Med 2018 Jun 17;25(2):360-363. Epub 2018 May 17.

Institute of Zoology, Poznań University of Life Sciences, Poznań, Poland.

Introduction: Tick abundance and the prevalence of the pathogens they carry have been increasing worldwide in the last decades, and is projected to increase even further. Despite the fact that problem is global, there still remain many gaps in the diagnosis and treatment of tick-borne diseases. The best protection from tick-borne pathogens, therefore, is prevention and avoidance of bites. Read More

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http://dx.doi.org/10.26444/aaem/89919DOI Listing

Sensitivity of African swine fever virus (ASFV) to heat, alkalinity and peroxide treatment in presence or absence of porcine plasma.

Vet Microbiol 2018 Jun 19;219:144-149. Epub 2018 Apr 19.

Department of Virology, Veterinary and Agrochemical Research Centre (CODA-CERVA), Groeselenberg 99, B-1180 Brussels, Belgium.

African swine fever virus (ASFV) is a highly resistant viraemic virus with devastating socio-economic impact. Its present epidemiology in Eastern Europe and Russia warrants increased biosecurity measures in Western Europe. This includes proactive precautions on traffic of pork products within and between areas that are officially free from ASF. Read More

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http://dx.doi.org/10.1016/j.vetmic.2018.04.025DOI Listing
June 2018
1 Read

Vital Signs: Trends in Reported Vectorborne Disease Cases - United States and Territories, 2004-2016.

MMWR Morb Mortal Wkly Rep 2018 May 4;67(17):496-501. Epub 2018 May 4.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Fort Collins, Colorado.

Introduction: Vectorborne diseases are major causes of death and illness worldwide. In the United States, the most common vectorborne pathogens are transmitted by ticks or mosquitoes, including those causing Lyme disease; Rocky Mountain spotted fever; and West Nile, dengue, and Zika virus diseases. This report examines trends in occurrence of nationally reportable vectorborne diseases during 2004-2016. Read More

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http://www.cdc.gov/mmwr/volumes/67/wr/mm6717e1.htm?s_cid=mm6
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http://dx.doi.org/10.15585/mmwr.mm6717e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933869PMC
May 2018
52 Reads

[A fatal case series of Rocky Mountain spotted fever in Sonora, México].

Biomedica 2018 Mar 15;38(1):69-76. Epub 2018 Mar 15.

Departamento de Medicina y Ciencias de la Salud, Universidad de Sonora, Hermosillo, México.

Introduction: Rocky Mountain spotted fever is a highly lethal infectious disease, particularly if specific treatment with doxycycline is given belatedly.

Objective: To describe the clinical profile of fatal Rocky Mountain spotted fever cases in hospitalized patients in the state of Sonora, México.

Materials And Methods: We conducted a cross-sectional study on a series of 47 deaths caused by Rickettsia rickettsii from 2013 to 2016. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.3507DOI Listing
March 2018
3 Reads

Artificial blood feeders for mosquito and ticks-Where from, where to?

Acta Trop 2018 Jul 3;183:43-56. Epub 2018 Apr 3.

The BioRobotics Institute, Sant'Anna School of Advanced Studies, viale Rinaldo Piaggio 34, 56025 Pontedera, Pisa, Italy; Department of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa, Italy. Electronic address:

Mosquito and tick feeding activity represent a key threat for humans, livestock, pets and wildlife worldwide. Rearing these vectors in laboratory conditions is extremely important to investigate basic facets of their biology, vector competence, new control strategies, as well as mechanisms of pesticide resistance. However, the use of animals or humans to provide blood for hematophagous arthropod feeding poses a strict limit to these researches, due to the accidental transmission of diseases, ethical problems concerning animal welfare, as well as expensive and time-consuming animal rearing procedures. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.04.009DOI Listing
July 2018
14 Reads

CXCL9 concentrations in cerebrospinal fluid and serum of patients with tick-borne encephalitis.

Arch Med Sci 2018 Mar 22;14(2):313-320. Epub 2016 Mar 22.

Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Bialystok, Poland.

Introduction: The aim of our current study was to evaluate cerebrospinal fluid (CSF) and serum CXCL9 concentrations and diagnostic usefulness of this molecule in tick-borne encephalitis (TBE). The study included TBE patients in the acute phase (TBE I) and after 2 weeks of follow-up (TBE II). The control group consisted of patients investigated for suspected central nervous system (CNS) infection, but with normal CSF findings. Read More

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http://dx.doi.org/10.5114/aoms.2016.58667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868655PMC
March 2018
4 Reads

Molecular Characterization and Phylogenetic Analysis of Anaplasma spp. and Ehrlichia spp. Isolated from Various Ticks in Southeastern and Northwestern Regions of Iran.

Vector Borne Zoonotic Dis 2018 05 20;18(5):252-257. Epub 2018 Mar 20.

9 Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences , Tehran, Iran .

Introduction: Anaplasma/Ehrlichia species are tick-transmitted pathogens that cause infections in humans and numerous domestic and wild animal species. There is no information available on the molecular characteristics and phylogenetic position of Anaplasma/Ehrlichia spp. isolated from tick species from different geographic locations in Iran. Read More

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http://dx.doi.org/10.1089/vbz.2017.2219DOI Listing
May 2018
6 Reads

Prevalence of Borrelia burgdorferi in ticks removed from skin of people and circumstances of being bitten - research from the area of Poland, 2012-2014.

Ann Agric Environ Med 2018 Mar 11;25(1):31-35. Epub 2017 Feb 11.

Institute of Health, State Higher Vocational School of Technology and Economic in Jaroslaw, Jaroslaw, Poland.

Introduction: During feeding, the tick sucks blood from the host along with the pathogens that are in the blood, simultaneously exchanging its own pathogens with the host. Humans can also be a host. It is important to understand the most typical circumstances in which people might become infected with Borrelia burgdorferi. Read More

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http://dx.doi.org/10.5604/12321966.1233906DOI Listing
March 2018
1 Read

Introduction to disease vectors.

Authors:
Robin B McFee

Dis Mon 2018 May 9;64(5):170-174. Epub 2018 Mar 9.

Debusk College of Osteopathic Medicine, Lincoln Memorial University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.disamonth.2018.01.003DOI Listing
May 2018
1 Read

The protective effect and diagnostic performance of NOX-5 in Crimean-Congo haemorrhagic fever patients.

J Med Microbiol 2018 Apr 6;67(4):543-548. Epub 2018 Mar 6.

1​Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey.

Introduction: Crimean-Congo haemorrhagic fever (CCHF) is an acute viral haemorrhagic disease. Reactive oxygen species that are mainly generated by the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) enzyme family have a pivotal role in the pathophysiology of many diseases. The serum levels of NOX isoforms in patients with CCHF have yet to be assessed. Read More

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http://dx.doi.org/10.1099/jmm.0.000712DOI Listing
April 2018
6 Reads

Short time window for transmissibility of African swine fever virus from a contaminated environment.

Transbound Emerg Dis 2018 Aug 19;65(4):1024-1032. Epub 2018 Feb 19.

DTU National Veterinary Institute, Technical University of Denmark, Lindholm, Kalvehave, Denmark.

Since the introduction of African swine fever virus (ASFV) into the Baltic states and Poland in 2014, the disease has continued to spread within these regions. In 2017, the virus spread further west and the first cases of disease were reported in the Czech Republic and Romania, in wild boar and domestic pigs, respectively. To control further spread, knowledge of different modes of transmission, including indirect transmission via a contaminated environment, is crucial. Read More

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http://dx.doi.org/10.1111/tbed.12837DOI Listing
August 2018
2 Reads

In vitro growth inhibition of Theileria equi by bumped kinase inhibitors.

Vet Parasitol 2018 Feb 1;251:90-94. Epub 2018 Jan 1.

Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA, 99164, USA.

Introduction: Theileria equi, an etiologic agent of equine piroplasmosis, is a tick-transmitted hemoprotozoan of the phylum Apicomplexa. Recent outbreaks of piroplasmosis in the United States have renewed interest in safe and effective treatment options. Although imidocarb dipropionate (IMD) is the drug of choice for clearance of T. Read More

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http://dx.doi.org/10.1016/j.vetpar.2017.12.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959018PMC
February 2018
1 Read

What mother know about vaccine preventable diseases?

Przegl Epidemiol 2017 ;71(4):595-602

Chair of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, Krakow

Introduction And Objective: The improving epidemiological situation of the most of communicable diseases causes, that the real and potential risks attributable to them have been forgotten. The aim of study was to determine the mothers knowledge about vaccine preventable diseases

Materials And Methods: A survey was conducted among 177 randomly selected mothers. The interviews with mothers hospitalized after childbearing in two hospitals in Krakow and Myslenice were conducted at the end of 2014 and in 2015

Results: The assessment of risk to develop an infectious diseases in unvaccinated children significantly varied among mothers. Read More

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January 2017
1 Read

Lyme disease in Poland in 2015

Przegl Epidemiol 2017 ;71(4):513-517

National Institute of Public Health –National Institute of Hygiene in Warsaw Department of Epidemiology

Introduction: Lyme disease is the most common tick-borne disease in Poland. Borrelia burgdorferi spirochete can occur in the whole country, which, according to ECDC, should be considered as an endemic area. Borrelia strains are transmitted to humans and certain other animals by Ixodes (1). Read More

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January 2017
3 Reads

Kyasanur Forest Disease Prevalence in Western Ghats Proven and Confirmed by Recent Outbreak in Maharashtra, India, 2016.

Vector Borne Zoonotic Dis 2018 03 16;18(3):164-172. Epub 2018 Jan 16.

1 Microbial Containment Complex, National Institute of Virology, Pune, India .

Introduction: Kyasanur forest disease (KFD) outbreak was confirmed in Dodamarg Taluka, Sindhudurga district (Maharashtra) in India during the year 2016. The rise in suspected KFD cases was reported in January 2016, peaked during March, and then declined gradually from April 2016. The outbreak was thoroughly investigated considering different socio-clinical parameters. Read More

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http://dx.doi.org/10.1089/vbz.2017.2129DOI Listing
March 2018
9 Reads
2.300 Impact Factor

Monitoring for the possible introduction of Crimean-Congo haemorrhagic fever virus in Italy based on tick sampling on migratory birds and serological survey of sheep flocks.

Prev Vet Med 2018 Jan 1;149:47-52. Epub 2017 Nov 1.

Istituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", Via Appia Nuova 1411, 00178 Rome, Italy.

Crimean-Congo haemorrhagic fever (CCHF), endemic in Africa, Asia, Eastern Europe and the Middle East, is caused by a tibovirus (CCHFV) transmitted in particular by the Hyalomma genus of the Ixodidae family that can remain attached to the host for up to 26days, which in case of migratory birds allows long distance carriage. Although CCHF in domestic ruminants is usually subclinical, they may become reservoirs and act as sentinels for the introduction and/or circulation of CCHFV. In this study, possible CCHFV introduction and circulation in Italy were monitored by tick sampling on migratory birds and by a serosurvey conducted on sheep. Read More

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http://dx.doi.org/10.1016/j.prevetmed.2017.10.014DOI Listing
January 2018
8 Reads

Design, construction and evaluation of multi-epitope antigens for diagnosis of Lyme disease.

Ann Agric Environ Med 2017 Dec 18;24(4):696-701. Epub 2017 Dec 18.

Laboratory of Biomedical Microbiology and Immunology, Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy, 041 81 Kosice, Slovakia.

Introduction: Introduction and objective. Lyme disease (LD) is the most common vector-borne disease in the temperate zone of the Northern Hemisphere. Diagnosis of LD is mainly based on clinical symptoms supported with serology (detection of anti-Borrelia antibodies) and is often misdiagnosed in areas of endemicity. Read More

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http://dx.doi.org/10.26444/aaem/80699DOI Listing
December 2017
8 Reads

Diagnosis and management of Lyme neuroborreliosis.

Authors:
John J Halperin

Expert Rev Anti Infect Ther 2018 01 26;16(1):5-11. Epub 2017 Dec 26.

a Department of Neurosciences , Overlook Medical Center , Summit , NJ , USA.

Introduction: The nervous system is involved in 10-15% of patients infected with B. burgdorferi, B. afzelii and B. Read More

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http://dx.doi.org/10.1080/14787210.2018.1417836DOI Listing
January 2018
11 Reads

Serological and molecular surveys of Babesia bovis and Babesia bigemina among native cattle and cattle imported from Thailand in Hue, Vietnam.

J Vet Med Sci 2018 Mar 15;80(2):333-336. Epub 2017 Dec 15.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan.

Serum and DNA from blood samples collected from Vietnamese yellow cattle (n=101) and cattle imported from Thailand (n=54) at a Vietnamese slaughter house were screened for Babesia bovis and Babesia bigemina infections by enzyme-linked immunosorbent assay (ELISA) and PCR. The positive rates determined by ELISA (B. bovis and B. Read More

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http://dx.doi.org/10.1292/jvms.17-0549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836773PMC
March 2018
0.780 Impact Factor

Borrelia miyamotoi: Should this pathogen be considered for the diagnosis of tick-borne infectious diseases in Spain?

Enferm Infecc Microbiol Clin 2018 11 26;36(9):568-571. Epub 2017 Nov 26.

Centro de Rickettsiosis y Enfermedades Transmitidas por Artrópodos Vectores, Departamento de Enfermedades Infecciosas, Hospital San Pedro-CIBIR, Logroño (La Rioja), Spain. Electronic address:

Introduction: Borrelia miyamotoi is a tick-borne pathogen belonging to the relapsing fever group. It had not been reported from Spain, but its wide distribution and the presence of the tick-vector (Ixodes ricinus) made us suspect its circulation. The aim of this study was to investigate the presence of Borrelia spp. Read More

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http://dx.doi.org/10.1016/j.eimc.2017.10.020DOI Listing
November 2018
9 Reads

Transmission of African swine fever virus from infected pigs by direct contact and aerosol routes.

Vet Microbiol 2017 Nov 4;211:92-102. Epub 2017 Oct 4.

DTU National Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark. Electronic address:

In 2014, African swine fever virus (ASFV) was introduced into the Baltic states and Poland. Since then, the disease has continued to spread within these regions, and recently, cases were reported in the Czech Republic and Romania. Currently, there is an increasing risk of ASFV introduction into Western Europe. Read More

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http://dx.doi.org/10.1016/j.vetmic.2017.10.004DOI Listing
November 2017
12 Reads

Artificial Infection of Ticks with Borrelia burgdorferi Using a Microinjection Method and Their Detection In Vivo Using Quantitative PCR Targeting flaB RNA.

Methods Mol Biol 2018 ;1690:105-114

Department of Veterinary Medicine, University of Maryland, College Park, MD, USA.

Borrelia burgdorferi is maintained in nature by a tick-rodent infection cycle where it traverses and colonizes a variety of host and vector tissues. A tick-borne murine model has been developed to study Lyme disease in the laboratory, which has a substantial impact in advancing our knowledge of spirochete infectivity and pathogenesis. Here, we detail a microinjection-based method for rapid and efficient infection of ticks with B. Read More

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http://dx.doi.org/10.1007/978-1-4939-7383-5_9DOI Listing
June 2018
2 Reads

Why is African swine fever still present in Sardinia?

Transbound Emerg Dis 2018 Apr 12;65(2):557-566. Epub 2017 Oct 12.

VISAVET Health Surveillance Centre and Animal Health Department, Veterinary School, Complutense University of Madrid, Madrid, Spain.

African swine fever (ASF) is an infectious disease of swine that has been present in Sardinia since 1978. Soon after introduction of the disease, several control and eradication programmes were established with limited success. Some researchers attributed the persistence of the disease in central and eastern areas to certain socio-economic factors, the existence of some local and traditional farming practices (i. Read More

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http://dx.doi.org/10.1111/tbed.12740DOI Listing
April 2018
20 Reads

Cerebral vasculitis and intracranial multiple aneurysms in a child with Lyme neuroborreliosis.

JMM Case Rep 2017 Apr 21;4(4):e005090. Epub 2017 Apr 21.

Department of Infectious Diseases, Division of Medicine, Faculty of Medicine, University of Turku, Turku University Hospital, P.O. Box 52, 20521 Turku, Finland.

Lyme borreliosis is a multisystem tick-borne disease caused by . Neurological manifestations are reported in up to 15 % of adult patients with Lyme disease, while the frequency among children is higher. The most common manifestations are painful radiculopathy, facial nerve paresis and lymphocytic meningitis. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630958PMC
April 2017
6 Reads

A glycosylated recombinant subunit candidate vaccine consisting of Ehrlichia ruminantium major antigenic protein1 induces specific humoral and Th1 type cell responses in sheep.

PLoS One 2017 28;12(9):e0185495. Epub 2017 Sep 28.

Utrecht Centre for Tick-Borne Diseases, FAO Reference Centre for Ticks and Tick-Borne Diseases, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, Utrecht, The Netherlands.

Heartwater, or cowdriosis, is a tick-borne disease of domestic and wild ruminants that is endemic in the Caribbean and sub-Saharan Africa. The disease is caused by an intracellular pathogen, Ehrlichia ruminantium and may be fatal within days of the onset of clinical signs with mortality rates of up to 90% in susceptible hosts. Due to the presence of competent tick vectors in North America, there is substantial risk of introduction of heartwater with potentially devastating consequences to the domestic livestock industry. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185495PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619772PMC
October 2017
2 Reads

Molecular detection of Borrelia burgdorferi sensu lato - An analytical comparison of real-time PCR protocols from five different Scandinavian laboratories.

PLoS One 2017 22;12(9):e0185434. Epub 2017 Sep 22.

Clinical Microbiology, Laboratory Medicine, Region Jönköping County, Sweden.

Introduction: Lyme borreliosis (LB) is the most common tick transmitted disease in Europe. The diagnosis of LB today is based on the patient´s medical history, clinical presentation and laboratory findings. The laboratory diagnostics are mainly based on antibody detection, but in certain conditions molecular detection by polymerase chain reaction (PCR) may serve as a complement. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185434PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609768PMC
October 2017
23 Reads

Simplifying sampling for African swine fever surveillance: Assessment of antibody and pathogen detection from blood swabs.

Transbound Emerg Dis 2018 Feb 17;65(1):e165-e172. Epub 2017 Sep 17.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald - Insel Riems, Germany.

African swine fever (ASF) is a notifiable disease with serious socio-economic consequences that has been present in wild boar in the Baltic States and Poland since 2014. An introduction of ASF is usually accompanied by increased mortality, making fallen wild boar and hunted animals with signs of disease the main target for early warning and passive surveillance. It is difficult, however, to encourage hunters and foresters to report and take samples from these cases. Read More

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http://dx.doi.org/10.1111/tbed.12706DOI Listing
February 2018
4 Reads

Diagnostic specificity of the African swine fever virus antibody detection enzyme-linked immunosorbent assay in feral and domestic pigs in the United States.

Transbound Emerg Dis 2017 Dec 18;64(6):1665-1668. Epub 2017 Sep 18.

Foreign Animal Disease Diagnostic Laboratory, Animal and Plant Health Inspection Services, United States Department of Agriculture, Greenport, NY, USA.

African swine fever (ASF) is a highly contagious haemorrhagic disease of pigs that has the potential to cause mortality nearing 100% in naïve animals. While an outbreak of ASF in the United States' pig population (domestic and feral) has never been reported, an introduction of the disease has the potential to cause devastation to the pork industry and food security. During the recovery phase of an outbreak, an antibody detection diagnostic assay would be required to prove freedom of disease within the previously infected zone and eventually nationwide. Read More

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http://dx.doi.org/10.1111/tbed.12717DOI Listing
December 2017
4 Reads

Analysis of the relationship between single nucleotide polymorphism of the CD209, IL-10, IL-28 and CCR5 D32 genes with the human predisposition to developing tick-borne encephalitis.

Postepy Hig Med Dosw (Online) 2017 Jan;71(1):788-796

Department of Infectious Diseases and Neuroinfections, Medical University in Białystok, Poland.

<b>Introduction: </b>It is known that in the pathogenesis of tick-borne encephalitis (TBE) various molecules play a significant role. The most prominent factors include IL-10, IL-28B, CD-209 and CCR5. It is reasonable to search for genetic predispositions to the development of various clinical forms of TBE related to the genetic variation of IL-10, IL-28B, CD-209 and CCR5. Read More

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January 2017
33 Reads

Molecular, epidemiological, haematological and biochemical evaluation in asymptomatic Theileria annulata infected cattle from an endemic region in Spain.

Ticks Tick Borne Dis 2017 10 25;8(6):936-941. Epub 2017 Aug 25.

Department of Animal Medicine and Surgery, College of Veterinary Medicine, Complutense University of Madrid, Avda. Puerta de Hierro s/n, 28040, Madrid, Spain.

Mediterranean theileriosis is one of the most fatal theilerioses, with considerable economic impact on livestock production. The potential consequences of asymptomatic infection on the animal's health and on the epidemiology in endemic regions are still unclear. The objectives of this study were to determine the molecular prevalence of T. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2017.08.006DOI Listing
October 2017
2 Reads

Identifying Attenuating Mutations: Tools for a New Vaccine Design against Flaviviruses.

Intervirology 2017 5;60(1-2):8-18. Epub 2017 Sep 5.

Arbovirus Group, Environment and Infectious Risks Unit, Institut Pasteur, Paris, France.

Emerging Flaviviruses pose an increasing threat to global human health. To date, human vaccines against yellow fever virus (YFV), Japanese encephalitis virus (JEV), dengue virus (DV), and tick-borne encephalitis virus (TBEV) exist. However, there is no human vaccine against other Flaviviruses such as Zika virus (ZIKV) and West Nile virus (WNV). Read More

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http://dx.doi.org/10.1159/000479966DOI Listing
May 2018
2 Reads

Infection of Ixodes ricinus by Borrelia burgdorferi sensu lato in peri-urban forests of France.

PLoS One 2017 28;12(8):e0183543. Epub 2017 Aug 28.

Centre National de Référence des Borrelia, Institut Pasteur, Paris, France.

Lyme borreliosis is the most common tick-borne disease in the northern hemisphere. In Europe, it is transmitted by Ixodes ticks that carry bacteria belonging to the Borrelia burgdorferi sensu lato complex. The objective of this work was to explore eco-epidemiological factors of Lyme borreliosis in peri-urban forests of France (Sénart, Notre-Dame and Rambouillet). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183543PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573218PMC
October 2017
13 Reads

Prevalence and distribution of Borrelia and Babesia species in ticks feeding on dogs in the U.K.

Med Vet Entomol 2018 03 28;32(1):14-22. Epub 2017 Aug 28.

Veterinary Parasitology and Ecology Group, School of Biological Sciences, University of Bristol, Bristol, U.K.

Ticks were collected during March-July 2015 from dogs by veterinarians throughout the U.K. and used to estimate current prevalences and distributions of pathogens. Read More

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http://dx.doi.org/10.1111/mve.12257DOI Listing
March 2018
1 Read

Quantitative approach for the risk assessment of African swine fever and Classical swine fever introduction into the United States through legal imports of pigs and swine products.

PLoS One 2017 10;12(8):e0182850. Epub 2017 Aug 10.

Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States of America.

The US livestock safety strongly depends on its capacity to prevent the introduction of Transboundary Animal Diseases (TADs). Therefore, accurate and updated information on the location and origin of those potential TADs risks is essential, so preventive measures as market restrictions can be put on place. The objective of the present study was to evaluate the current risk of African swine fever (ASF) and Classical swine fever (CSF) introduction into the US through the legal importations of live pigs and swine products using a quantitative approach that could be later applied to other risks. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182850PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552331PMC
October 2017
2 Reads

[Amoxicillin-induced skin rash sparing a plaque of erythema migrans: Renbök phenomenon: Case report and literature review].

Ann Dermatol Venereol 2018 Jan 3;145(1):43-47. Epub 2017 Aug 3.

Service de dermatologie, centre hospitalier René-Dubos, 6, avenue de l'île-de-France, 95300 Pontoise, France.

Introduction: Renbök phenomenon describes the inhibition of a lesion when a different one appears. We describe the first case of Renbök phenomenon occurring in a context of erythema migrans (EM) spared by an amoxicillin-induced skin rash and we also present a literature review.

Case Report: A 60-year-old patient was treated with amoxicillin for EM on the right knee and subsequently developed generalized erythema as a result of an antibiotic-induced skin rash, with sparing of the area previously affected by EM. Read More

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http://dx.doi.org/10.1016/j.annder.2017.06.013DOI Listing
January 2018

Systematic literature review comparing rapid 3-dose administration of the GSK tick-borne encephalitis vaccine with other primary immunization schedules.

Expert Rev Vaccines 2017 09 4;16(9):919-932. Epub 2017 Aug 4.

d GSK , Wavre , Belgium.

Introduction: Tick-borne encephalitis (TBE), which is endemic across large regions of Europe and Asia, is most effectively prevented through vaccination. Three-dose primary TBE vaccination schedules are either rapid (0,7,21-days) or conventional (0,28-84-days, 9-12-months). The second dose can also be administered at 14 days for faster priming and sero-protection). Read More

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http://dx.doi.org/10.1080/14760584.2017.1358620DOI Listing
September 2017
5 Reads

Estimation of the transmission dynamics of African swine fever virus within a swine house.

Epidemiol Infect 2017 10 3;145(13):2787-2796. Epub 2017 Aug 3.

Dynamical Systems, Department of Applied Mathematics and Computer Sciences,Technical University of Denmark,Lyngby,Denmark.

The spread of African swine fever virus (ASFV) threatens to reach further parts of Europe. In countries with a large swine production, an outbreak of ASF may result in devastating economic consequences for the swine industry. Simulation models can assist decision makers setting up contingency plans. Read More

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http://dx.doi.org/10.1017/S0950268817001613DOI Listing
October 2017
1 Read

Pig empire under infectious threat: risk of African swine fever introduction into the People's Republic of China.

Vet Rec 2017 Jul;181(5):117

Animal, Health, Territories, Risks and Ecosystems, CIRAD, Montpellier, France.

Pig production and pork consumption are very important to the People's Republic of China for both economic and cultural reasons. The incursion and spread of a disease such as African swine fever (ASF), which emerged in Eastern Europe in 2007, could have devastating socioeconomic consequences for both the Chinese and the global pig industry. The Chinese government consequently attributes a very high priority to ASF and is actively seeking to improve its preparedness. Read More

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http://dx.doi.org/10.1136/vr.103950DOI Listing
July 2017
37 Reads

The impact of illegal waste sites on a transmission of zoonotic viruses.

Virol J 2017 07 20;14(1):134. Epub 2017 Jul 20.

Department of Biodiversity, Faculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Glagoljaška 8, 6000, Koper, Slovenia.

Background: Illegal waste disposal impacts public health and causes aesthetic and environmental pollution. Waste disposed in places without permitted and controlled facilities can provide a ready source of nutrition and shelter for rodents and thus promote the spread of their ecto- and endoparasites. The presence of two distinct zoonotic viruses, lymphocytic choriomeningitis virus (LCMV) and tick-borne encephalitis virus (TBEV), was searched at illegal waste sites. Read More

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http://dx.doi.org/10.1186/s12985-017-0798-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520353PMC
July 2017
2 Reads

Serosurvey for Crimean-Congo hemorrhagic fever virus infections in ruminants in Katanga province, Democratic Republic of the Congo.

Ticks Tick Borne Dis 2017 10 3;8(6):858-861. Epub 2017 Jul 3.

Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald - Isle of Riems, Germany. Electronic address:

Crimean-Congo hemorrhagic fever virus (CCHFV) has been detected in many African countries. Unfortunately, little is known about the current CCHFV situation in most of those countries including the Democratic Republic of the Congo (DRC). In over 50 years, three human CCHF cases have been detected in DRC but no seroepidemiological investigation was performed so far. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2017.07.001DOI Listing
October 2017
6 Reads

Seropositivity for Rickettsia spp. and Ehrlichia spp. in the human population of Mato Grosso, Central-Western Brazil.

Rev Soc Bras Med Trop 2017 May-Jun;50(3):399-403

Programa de Pós-Graduação em Ciências da Saúde, Laboratório de Virologia, Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil.

Introduction: The epidemiology of Rickettsia and Ehrlichia species infection is underestimated in Mato Grosso State.

Methods: : Serum samples obtained during a Dengue outbreak in 2011-2012 were tested via indirect immunofluorescence and/or ELISA.

Results: : Samples from 19/506 (3. Read More

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http://dx.doi.org/10.1590/0037-8682-0318-2016DOI Listing
July 2017
13 Reads