2,950 results match your criteria Tick-Borne Diseases Ehrlichiosis


Emerging tick-borne pathogens of public health importance: a mini-review.

J Med Microbiol 2020 Jun 1;69(6):781-791. Epub 2020 Jun 1.

Department of Entomology, Rutgers University, New Brunswick, NJ, USA.

Ticks are the most important vectors of human pathogens, leading to increased public health burdens worldwide. Tick-borne pathogens include viruses (e.g. Read More

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http://dx.doi.org/10.1099/jmm.0.001206DOI Listing

Ehrlichiosis Presenting as Hemophagocytic Lymphohistiocytosis in an Immunocompetent Adult.

IDCases 2020 12;20:e00813. Epub 2020 May 12.

University of Missouri-Columbia, Department of Medicine, Division of Infectious Diseases, 1 Hospital Dr, Columbia, MO 65201, United States.

Hemophagocytic Lymphohistiocytosis (HLH) is a fatal, immunologic syndrome characterized by dysregulated tissue inflammation. HLH can be either primary or secondary; with the latter typically resulting from an infection. Diagnosis requires five or more of the following: fever, splenomegaly, cytopenia, hypertriglyceridemia, hemophagocytosis via biopsy, low natural killer (NK) cell activity, elevated ferritin and soluble CD25 level (sCD25). Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235617PMC

Committee Opinion No. 399: Management of Tick Bites and Lyme Disease During Pregnancy.

J Obstet Gynaecol Can 2020 05;42(5):644-653

Halifax, NS.

Objective: Lyme disease is an emerging infection in Canada caused by the bacterium belonging to the Borrelia burgdorferi sensu lato species complex, which is transmitted via the bite of an infected blacklegged tick. Populations of blacklegged ticks continue to expand and are now established in different regions in Canada. It usually takes more than 24 hours of tick attachment to transfer B. Read More

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http://dx.doi.org/10.1016/j.jogc.2020.01.001DOI Listing

Predominant risk factors for tick-borne co-infections in hunting dogs from the USA.

Parasit Vectors 2020 May 13;13(1):247. Epub 2020 May 13.

Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, 52242, USA.

Background: Both incidence and geographical range of tick-borne disease has increased across the USA. Similar to people, dogs are hosts for Anaplasma spp., Babesia spp. Read More

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http://dx.doi.org/10.1186/s13071-020-04118-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218638PMC
May 2020
3.430 Impact Factor

Emerging and neglected zoonoses in transplant population.

World J Transplant 2020 Mar;10(3):47-63

Department of Virology, Croatian Institute of Public Health; School of Medicine, University of Zagreb, Zagreb 10000, Croatia.

Zoonoses represent a problem of rising importance in the transplant population. A close relationship and changes between human, animal and environmental health ("One Health" concept) significantly influence the transmission and distribution of zoonotic diseases. The aim of this manuscript is to perform a narrative review of the published literature on emerging and neglected zoonoses in the transplant population. Read More

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http://dx.doi.org/10.5500/wjt.v10.i3.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109593PMC

Tick-Borne Diseases in the United States.

Clin Chem 2020 Apr;66(4):537-548

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

Background: Tick-borne diseases are an important cause of human morbidity and mortality in the United States. The past several decades have witnessed an increase in both the number of recognized tick-borne pathogens and the number of tick-borne disease cases, whereas tick surveys have revealed substantial geographic expansions of tick populations throughout the country. Multiple laboratory testing options exist for diagnosis of tick-borne diseases, including serology, microscopy, and molecular-based methods. Read More

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http://dx.doi.org/10.1093/clinchem/hvaa040DOI Listing

Case 10-2020: An 83-Year-Old Man with Pancytopenia and Acute Renal Failure.

N Engl J Med 2020 03;382(13):1258-1266

From the Departments of Medicine (D.B.S., R.S.K.L., S.E.T.), Radiology (E.W.Z.), and Pathology (V.N., S.E.T.), Massachusetts General Hospital, and the Departments of Medicine (D.B.S., R.S.K.L., S.E.T.), Radiology (E.W.Z.), and Pathology (V.N., S.E.T.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1916250DOI Listing

Discovery of Virulence Genes of Obligatory Intracellular Bacteria by Random Mutagenesis.

Front Cell Infect Microbiol 2020 4;10. Epub 2020 Feb 4.

Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, United States.

spp. are emerging tick-borne obligatory intracellular bacteria that cause febrile and sometimes fatal diseases with abnormal blood cell counts and signs of hepatitis. HF strain provides an excellent mouse disease model of fatal human ehrlichiosis. Read More

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http://dx.doi.org/10.3389/fcimb.2020.00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010607PMC
February 2020

Increased Incidence of Infections in the United States, 2012 Through 2016.

Vector Borne Zoonotic Dis 2020 Jul 20;20(7):547-550. Epub 2020 Feb 20.

Department of Wildlife and Fisheries Sciences, Texas A&M University, College Station, Texas, USA.

Human ehrlichioses are tick-borne diseases that have been increasing in incidence in the United States during recent years. is one of the primary bacteria that cause ehrlichiosis in humans, which typically results in fever-like symptoms, but may also be fatal if left untreated. infections are reported to the Centers for Disease Control and Prevention (CDC) through the National Notifiable Diseases Surveillance System (NNDSS). Read More

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http://dx.doi.org/10.1089/vbz.2019.2595DOI Listing
July 2020
2.298 Impact Factor

Canine vector-borne disease in domestic dogs on Isla Santa Cruz, Galápagos.

Vet Parasitol Reg Stud Reports 2020 01 17;19:100373. Epub 2020 Jan 17.

Cornell University, College of Veterinary Medicine, 602 Tower Road, Ithaca, NY 14850, United States of America.

Vector-borne diseases result in significant morbidity and mortality in domestic dogs in tropical and subtropical regions and also pose a potential threat to wildlife species and humans. Ehrlichia canis, the causative agent of canine monocytic ehrlichiosis (CME), has a high reported seroprevalence in dogs on Santa Cruz in the Galápagos Islands, Ecuador. Veterinary diagnostic and treatment resources are often scarce and clinical follow-up is lacking in the Galápagos. Read More

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http://dx.doi.org/10.1016/j.vprsr.2020.100373DOI Listing
January 2020

Detection of Ehrlichia spp. and Anaplasma phagocytophilum in whole blood specimens using a duplex real-time PCR assay on the ARIES instrument.

Ticks Tick Borne Dis 2020 May 1;11(3):101387. Epub 2020 Feb 1.

University of Louisville, Department of Medicine, Division of Infectious Diseases, Infectious Diseases Laboratory, 511 S. Floyd St, Medical Dental Research Building Room 104, Louisville, KY 40292 USA. Electronic address:

Cases of tick-borne diseases are increasing in the United States, and new tick-borne pathogen species causing human illness are being discovered. The specific etiology is generally difficult to diagnose based on clinical signs and symptoms alone, because of their generalized nature and often lack of a known tick bite. For some infections, such as Lyme disease and spotted fever group rickettsioses, serology remains the most appropriate laboratory diagnostic tool, but for others such as anaplasmosis, ehrlichiosis, and babesiosis, direct detection in the blood is preferred for rapid diagnosis. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2020.101387DOI Listing

Molecular prevalence of in sheep from Iraq.

Open Vet J 2019 10 25;9(3):238-245. Epub 2019 Aug 25.

Department of Veterinary Internal and Preventive Medicine, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq.

Background: Tick-borne diseases are widely distributed among animal populations and are responsible for significant economic losses. However, little attention has been offered for screening such infections world widely. is among those neglected tick-borne pathogens, particularly in the developing countries. Read More

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http://dx.doi.org/10.4314/ovj.v9i3.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794391PMC
October 2019

Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection.

mBio 2020 01 28;11(1). Epub 2020 Jan 28.

Department of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

Diverse intracellular pathogens rely on eukaryotic cell surface disulfide reductases to invade host cells. Pharmacologic inhibition of these enzymes is cytotoxic, making it impractical for treatment. Identifying and mechanistically dissecting microbial proteins that co-opt surface reductases could reveal novel targets for disrupting this common infection strategy. Read More

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http://dx.doi.org/10.1128/mBio.03141-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989111PMC
January 2020

Ehrlichia canis TRP36 diversity in naturally infected-dogs from an urban area of Colombia.

Ticks Tick Borne Dis 2020 May 7;11(3):101367. Epub 2020 Jan 7.

Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, Sealy Institute for Vaccine Development, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0609, USA. Electronic address:

Ehrlichia canis is the etiologic agent of a highly prevalent tick-borne disease, canine monocytic ehrlichiosis (CME). Four defined E. canis genotypes based on the trp36 gene sequences have been reported, three of them identified in North or South America. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2019.101367DOI Listing

Prevalence of Infection and Co-Infection and Presence of Rickettsial Endosymbionts in (Acari: Ixodidae) in Connecticut, USA.

J Parasitol 2020 02;106(1):30-37

Department of Environmental Sciences, The Connecticut Agricultural Experiment Station, 123 Huntington Street, New Haven, Connecticut 06511.

is currently known to transmit 7 pathogens responsible for Lyme disease, anaplasmosis, babesiosis, tick-borne relapsing fever, ehrlichiosis, and Powassan encephalitis. can also be colonized by endosymbiotic bacteria including those in the genus of . We screened 459 ticks submitted to the Connecticut Agricultural Experiment Station Tick Testing Laboratory with the objectives to (1) examine differences in infection prevalence of , , , and , (2) evaluate whether prevalence of co-infections occur at the same frequency that would be expected based on single infection, and (3) determine the presence of rickettsial endosymbionts in . Read More

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February 2020

First report of human ehrlichiosis in Turkey.

Turk J Pediatr 2019 ;61(2):267-270

Department of Public Health Institution of Turkey, National High Risk Pathogens Reference Laboratory, Ankara, Turkey.

Emiroğlu M, Çelebi B. First report of human ehrlichiosis in Turkey. Turk J Pediatr 2019; 61: 267-270. Read More

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http://dx.doi.org/10.24953/turkjped.2019.02.017DOI Listing

A retrospective study of vector-borne disease prevalence in dogs with proteinuria: Southeastern United States.

J Vet Intern Med 2020 Mar 8;34(2):742-753. Epub 2020 Jan 8.

The Department of Clinical Sciences and North Carolina State University, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Background: Proteinuria is a risk factor for progressive kidney injury in dogs. Enhanced understanding of potential associations between canine vector-borne diseases (CVBD) and proteinuria is needed.

Objectives: To determine the proportion of evaluated proteinuric dogs exposed to ≥1 CVBD, including Babesia spp. Read More

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http://dx.doi.org/10.1111/jvim.15610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096618PMC

Seroprevalence of viral and vector-borne bacterial pathogens in domestic dogs (Canis familiaris) in northern Botswana.

PLoS One 2020 8;15(1):e0220593. Epub 2020 Jan 8.

Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States of America.

Background: Domestic dogs (Canis familiaris) have the potential to act as disease reservoirs for wildlife and are important sentinels for common circulating pathogens. Therefore, the infectious disease seroprevalence among domestic dogs in northern Botswana may be indicative of pathogen exposure of various wildlife species. The objective of this study was to assess the seroprevalence of Ehrlichia spp. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220593PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949005PMC

Occurrence of Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti in Ixodes ricinus ticks collected from selected areas of Opolskie Province in south-west Poland.

Ann Agric Environ Med 2019 Dec 17;26(4):544-547. Epub 2019 Jul 17.

Department of Parasitology, Medical University of Silesia, Katowice, Poland.

Introduction: Ticks (Acari: Ixodida) are vectors and/or reservoirs of many pathogens, i.e. Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti. Read More

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http://dx.doi.org/10.26444/aaem/110214DOI Listing
December 2019

Phylogenetic profiling for zoonotic Ehrlichia spp. from ixodid ticks in the Eastern Cape, South Africa.

Transbound Emerg Dis 2020 May 8;67(3):1247-1256. Epub 2020 Jan 8.

Sefako Makgatho Health Sciences University, Pretoria, South Africa.

Ticks are obligate hematophagous parasite of vertebrate that transmit a range of pathogenic microorganisms that can cause diseases in livestock and humans. The range of tick-borne disease causative agents infecting domestic animals and humans has recently increased. Several significant zoonotic tick-borne diseases such as ehrlichiosis among others are on the increase worldwide. Read More

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http://dx.doi.org/10.1111/tbed.13460DOI Listing

Determining Effects of Winter Weather Conditions on Adult (Acari: Ixodidae) Survival in Connecticut and Maine, USA.

Insects 2019 Dec 21;11(1). Epub 2019 Dec 21.

Department of Entomology, Texas A&M University, TAMU 2475, College Station, TX 77843, USA.

The lone star tick ( L.) is native to the United States, with its primary range encompassing the Southeast and portions of the Midwest. It is an aggressive ectoparasite that actively seeks out hosts through detection of carbon dioxide and vibrations and can transfer ehrlichiosis-causing bacteria as well as a carbohydrate that causes alpha-gal syndrome (red meat allergy) in humans. Read More

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http://dx.doi.org/10.3390/insects11010013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023149PMC
December 2019

[Effectivity of diagnostic methods for the detection of human and canine monocytic ehrlichiosis].

Rev Chilena Infectol 2019 Oct;36(5):650-655

Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, México.

Ehrlichiosis is a disease transmitted by tick's bite that affect dogs and humans caused by the species Ehrlichia canis and E. chaffeensis, respectively. These bacteria are obligated intracellular gram negatives, with a cocoid to pleomorph aspect and can infect monocytes and trigger symptoms such as high fever, anorexia, thrombocytopenia, hemorrhages, anemia, and some serious problems such as splenomegaly, hepatomegaly and meningitis. Read More

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http://dx.doi.org/10.4067/S0716-10182019000500650DOI Listing
October 2019

Prevention of transmission of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum by Ixodes spp. ticks to dogs treated with the Seresto® collar (imidacloprid 10% + flumethrin 4.5%).

Parasitol Res 2020 Jan 16;119(1):299-315. Epub 2019 Nov 16.

Bayer Animal Health GmbH, 51373, Leverkusen, Germany.

The capability of imidacloprid 10% + flumethrin 4.5% (Seresto®) collars to prevent transmission of Borrelia burgdorferi sensu lato (Bbsl) and Anaplasma phagocytophilum (Ap) by naturally infected ticks was evaluated in two studies with 44 dogs. In each study, one group served as non-treated control, whereas the other groups were treated with the Seresto® collar. Read More

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http://dx.doi.org/10.1007/s00436-019-06394-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942034PMC
January 2020

Liver Is a Generative Site for the B Cell Response to Ehrlichia muris.

Immunity 2019 12 12;51(6):1088-1101.e5. Epub 2019 Nov 12.

Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

The B cell response to Ehrlichia muris is dominated by plasmablasts (PBs), with few-if any-germinal centers (GCs), yet it generates protective immunoglobulin M (IgM) memory B cells (MBCs) that express the transcription factor T-bet and harbor V-region mutations. Because Ehrlichia prominently infects the liver, we investigated the nature of liver B cell response and that of the spleen. B cells within infected livers proliferated and underwent somatic hypermutation (SHM). Read More

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http://dx.doi.org/10.1016/j.immuni.2019.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955021PMC
December 2019

Isolation and Characterization of a Novel Pathogenic Strain of .

Microorganisms 2019 Nov 5;7(11). Epub 2019 Nov 5.

UMR BIPAR, INRA, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, 94700 Maisons-Alfort, France.

The genus is composed of tick-borne obligate intracellular gram-negative alphaproteobacteria of the family Anaplasmataceae. includes important pathogens affecting canids (, , and ), rodents (), and ruminants (). , an closely related to , was initially reported in Canada and Brazil. Read More

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http://dx.doi.org/10.3390/microorganisms7110528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921006PMC
November 2019

Human Case of Ehrlichia chaffeensis Infection, Taiwan.

Emerg Infect Dis 2019 11;25(11):2141-2143

In 2018, an immunosuppressed woman in southern Taiwan had onset of fever, chills, myalgia, malaise, thrombocytopenia, lymphocytopenia, and elevated hepatic transaminases. Investigation revealed infection with Ehrlichia chaffeensis. This autochthonous case of human monocytotropic ehrlichiosis was confirmed by PCR, DNA sequencing, and seroconversion. Read More

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http://dx.doi.org/10.3201/eid2511.190665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810210PMC
November 2019

Tick Bite Risk and Tick-Borne Disease Perceptions of School District Administrators in the Mid-Atlantic United States.

J Sch Health 2019 12 14;89(12):959-968. Epub 2019 Oct 14.

Northeastern IPM Center, 340 Tower Road, Cornell University, Ithaca, NY, 14853.

Background: Lyme disease is a common tick-borne disease in the northeastern and midwestern United States. School-aged children aged 5-15 years are at high risk for contracting Lyme disease. Many school campuses in the mid-Atlantic United States are in areas that are near, or border with, wooded habitat. Read More

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http://dx.doi.org/10.1111/josh.12835DOI Listing
December 2019
2 Reads

Trends in canine seroprevalence to Borrelia burgdorferi and Anaplasma spp. in the eastern USA, 2010-2017.

Parasit Vectors 2019 Oct 14;12(1):476. Epub 2019 Oct 14.

IDEXX Laboratories, Inc., Westbrook, Maine, USA.

Background: Borrelia burgdorferi and Anaplasma phagocytophilum are tick-borne infections transmitted by Ixodes scapularis in the eastern USA; both agents cause disease in dogs and people. To characterize changes in seroprevalence over time, Cochran Armitage trend tests were used to evaluate percent positive test results for antibodies to B. burgdorferi and Anaplasma spp. Read More

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http://dx.doi.org/10.1186/s13071-019-3735-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791011PMC
October 2019
1 Read

Molecular detection of Anaplasma phagocytophilum in wild carnivores in north-eastern Poland.

Parasit Vectors 2019 Oct 7;12(1):465. Epub 2019 Oct 7.

Witold Stefański Institute of Parasitology, Polish Academy of Sciences, Twarda 51/55, 00-818, Warsaw, Poland.

Background: Anaplasma phagocytophilum is an obligate parasitic intracellular bacterium. It is the causative agent of granulocytic anaplasmosis, with effects on human and animal health. In Europe, the pathogen is mainly transmitted among a wide range of vertebrate hosts by blood-sucking arthropods. Read More

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http://dx.doi.org/10.1186/s13071-019-3734-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781336PMC
October 2019

Assessing the clinical and bacteriological outcomes of vaccination with recombinant Asp14 and OmpA against A. phagocytophilum in sheep.

Vet Immunol Immunopathol 2019 Dec 11;218:109936. Epub 2019 Sep 11.

Norwegian University of Life Sciences, Faculty of Veterinary Medicine, Department of Production Animal Clinical Science, Ullevålsveien 72, 0454, Oslo, Norway.

Anaplasma phagocytophilum is a tick borne bacterium, causing disease in sheep and other mammals, including humans. The bacterium has great economic and animal welfare implications for sheep husbandry in Northern Europe. With the prospect of a warmer and more humid climate, the vector availability will likely increase, resulting in a higher prevalence of A. Read More

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http://dx.doi.org/10.1016/j.vetimm.2019.109936DOI Listing
December 2019
1.535 Impact Factor

Laboratory Blood-Based Testing for Non-Lyme Disease Tick-Borne Infections at a National Reference Laboratory.

Am J Clin Pathol 2020 01;153(1):139-145

Quest Diagnostics, Secaucus, NJ.

Objectives: We evaluated trends in non-Lyme disease tick-borne disease (NLTBI) testing at a national reference laboratory.

Methods: Testing data performed at Quest Diagnostics during 2010 to 2016 were analyzed nationally and at the state level.

Results: Testing and positivity for most NLTBIs increased dramatically from 2010 through 2016 based on testing from a large reference laboratory. Read More

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http://dx.doi.org/10.1093/ajcp/aqz139DOI Listing
January 2020
1 Read

Detection of Rickettsiae, Borreliae, and Ehrlichiae in Ticks Collected from Walker County, Texas, 2017-2018.

Insects 2019 Sep 25;10(10). Epub 2019 Sep 25.

Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0609, USA.

Cases of tick-borne diseases, including spotted fever rickettsioses, borreliosis, babesiosis, anaplasmosis and ehrlichiosis, in the United States and territories have more than doubled from 2004 to 2016 and account for 77% of all vector-borne disease reports. In an effort to inform control efforts, the presence of tick-borne pathogens and their vectors was assessed in a recreational park in Walker County, Texas. Here we report data from questing ticks collected on three dates from June 2017 to June 2018. Read More

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http://dx.doi.org/10.3390/insects10100315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836155PMC
September 2019
1 Read

Associations between clinical canine leishmaniosis and multiple vector-borne co-infections: a case-control serological study.

BMC Vet Res 2019 Sep 18;15(1):331. Epub 2019 Sep 18.

Molecular Diagnostic Unit, Diagnostic Laboratories, Bristol Veterinary School and Langford Vets, University of Bristol, Langford, UK.

Background: Dogs that have clinical leishmaniosis (ClinL), caused by the parasite Leishmania infantum, are commonly co-infected with other pathogens, especially vector-borne pathogens (VBP). A recent PCR-based study found that ClinL dogs are more likely to be additionally infected with the rickettsial bacteria Ehrlichia canis. Further information on co-infections in ClinL cases with VBP, as assessed by serology, is required. Read More

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http://dx.doi.org/10.1186/s12917-019-2083-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749678PMC
September 2019

Ehrlichia canis in dogs of Mexico: Prevalence, incidence, co-infection and factors associated.

Comp Immunol Microbiol Infect Dis 2019 Dec 5;67:101351. Epub 2019 Sep 5.

Campus de Ciencias Biológicas y Agropecuarias, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Mérida, Yucatán, México.

Rickettsial infections in dogs of Mexico were investigated. A total of 246 dogs were blood sampled and initially screened to detect Ehrlichia canis, E. chaffeensis, E. Read More

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http://dx.doi.org/10.1016/j.cimid.2019.101351DOI Listing
December 2019
1 Read

Molecular identification of vector-borne organisms in Ehrlichia seropositive Nicaraguan horses and first report of Rickettsia felis infection in the horse.

Acta Trop 2019 Dec 10;200:105170. Epub 2019 Sep 10.

Vector Borne Disease Diagnostic Laboratory, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.

Certain vector-borne organisms serve as etiological agents of equine disease. After previously identifying a new Ehrlichia species in horses from Mérida, we aimed to determine the infection frequency and screen for a wide range of vector-borne organisms from 93 tick-exposed, Ehrlichia seropositive horses in this region. PCR assays were performed to identify infection by organisms within the following genera: Anaplasma, Babesia, Bartonella, Ehrlichia, Leishmania, Mycoplasma, Neorickettsia, Rickettsia and Theileria. Read More

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http://dx.doi.org/10.1016/j.actatropica.2019.105170DOI Listing
December 2019
2.270 Impact Factor

Safety of an extended-release injectable moxidectin suspension formulation (ProHeart 12) in dogs.

Parasit Vectors 2019 Sep 6;12(1):433. Epub 2019 Sep 6.

Zoetis, Kalamazoo, MI, 49007, USA.

Background: The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Read More

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http://dx.doi.org/10.1186/s13071-019-3690-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728954PMC
September 2019

Knowledge and prevention of tickborne diseases among Hispanic and non-Hispanic residents of Maryland and Virginia.

Zoonoses Public Health 2019 11 3;66(7):805-812. Epub 2019 Sep 3.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado.

Tickborne diseases (TBDs) such as Lyme disease (LD), babesiosis, ehrlichiosis and Rocky Mountain spotted fever cause substantial morbidity and even mortality in the USA. Data indicate that Hispanic populations may be at greater risk for occupational exposure to ticks and disseminated LD; however, information on knowledge and practices of Hispanic populations regarding TBDs is limited. We surveyed 153 Hispanic and 153 non-Hispanic residents of Maryland and Virginia to assess awareness of TBDs, prevention practices and risk of tick encounters. Read More

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http://dx.doi.org/10.1111/zph.12627DOI Listing
November 2019
2 Reads

Sequence Determinants Spanning -10 Motif and Spacer Region Implicated in Unique Sigma 32-Dependent Promoter Activity of Gene.

Front Microbiol 2019 2;10:1772. Epub 2019 Aug 2.

Center of Excellence for Vector-Borne Diseases, Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.

is an obligate intracellular tick-borne bacterium that causes human monocytic ehrlichiosis. Studying gene regulation is challenge, as this and related rickettsiales lack natural plasmids and mutagenesis experiments are of a limited scope. contains only two sigma factors, σ and σ. Read More

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http://dx.doi.org/10.3389/fmicb.2019.01772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687850PMC

Prevalence of Orientia tsutsugamushi, Anaplasma phagocytophilum and Leptospira interrogans in striped field mice in Gwangju, Republic of Korea.

PLoS One 2019 16;14(8):e0215526. Epub 2019 Aug 16.

Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Republic of Korea.

This study investigated the prevalence of Orientia tsutsugamushi, Anaplasma phagocytophilum, and Leptospira interrogans in wild rodents through molecular detection using organ samples and through serological assay using blood samples of mice collected from two distinct sites in Gwangju Metropolitan City, Republic of Korea (ROK). A total of 47 wild rodents, identified as Apodemus agrarius (A. agrarius), were captured from June to August 2016. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215526PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697328PMC

[Molecular-genetic monitoring as the basis of modern epidemiological surveillance of tick-borne infections.]

Klin Lab Diagn 2019 ;64(7):424-429

Somov Institute of Epidemiology and Microbiology, 690087, Vladivostok, Russia.

Molecular genetic monitoring of natural focal of tick-borne infections in the epidemic season of 2018 revealed infectiousness of ixodid ticks causative agents of tick-borne encephalitis (0.58% of cases), Lyme disease (31% of cases), human monocytic ehrlichiosis (1.6% of cases) and granulocytic anaplasmosis (3. Read More

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http://dx.doi.org/10.18821/0869-2084-2019-64-7-424-429DOI Listing
August 2019
4 Reads

Retrospective study of canine infectious haemolytic anaemia cases reveals the importance of molecular investigation in accurate postmortal diagnostic protocols.

Comp Immunol Microbiol Infect Dis 2019 Aug 9;65:81-87. Epub 2019 May 9.

Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia. Electronic address:

Infectious haemolytic anaemia (IHA) in dogs share similar clinical signs including fever, lethargy, icterus, paleness of mucous membranes and splenomegaly. Postmortal findings are similar and, without additional diagnostic methods, an accurate aetiological diagnosis is difficult to achieve. In order to investigate causes of lethal IHA in Croatian dogs, we performed a retrospective study on archived formalin-fixed, paraffin-embedded tissue blocks (FFPEB) from dogs that died due to haemolytic crisis, using microscopic and molecular diagnostic tools to determine the aetiological cause of disease. Read More

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http://dx.doi.org/10.1016/j.cimid.2019.05.006DOI Listing
August 2019
4 Reads
2.015 Impact Factor

Molecular detection and genetic characterisation of pathogenic Theileria, Anaplasma and Ehrlichia species among apparently healthy sheep in central and western Kenya.

Onderstepoort J Vet Res 2019 Jun 13;86(1):e1-e8. Epub 2019 Jun 13.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine.

Tick-borne diseases (TBDs) caused by Theileria, Babesia, Anaplasma and Ehrlichia species are common in tropical and subtropical regions. In this study, we investigated the presence and genetic diversity of Theileria spp., Anaplasma ovis, B. Read More

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http://dx.doi.org/10.4102/ojvr.v86i1.1630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620505PMC
June 2019
8 Reads

Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro.

Acta Parasitol 2019 Dec 6;64(4):769-778. Epub 2019 Dec 6.

Department of Infectious Animal Diseases and Bee Diseases, Faculty of Veterinary Medicine, University of Belgrade, Belgrade, Serbia.

Purpose: The incidence of vector-borne zoonoses has been increasing in Europe as a result of global climate change, and rickettsioses are a significant etiologic entity among these infections. The objective of this study was to investigate the seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in dogs in Montenegro.

Methods: The seroepidemiological study covered 259 dogs, of which 155 were owned dogs suspected of infection with agents of rickettsial aetiology from the continental (Podgorica) or five coastal municipalities of Montenegro (Budva, Herceg Novi, Kotor, Ulcinj and Bar), and 104 dogs were from a public shelter in Podgorica. Read More

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http://dx.doi.org/10.2478/s11686-019-00098-wDOI Listing
December 2019

Molecular Detection of Anaplasma phagocytophilum from Larvae of Haemaphysalis longicornis in Ibaraki, Japan.

Jpn J Infect Dis 2019 Nov 28;72(6):423-425. Epub 2019 Jun 28.

United Graduate School of Veterinary Science, Gifu University.

We collected 1,084 ticks by flagging vegetation in Tsukuba and Moriya (Ibaraki, Japan), where several cases of canine granulocytic anaplasmosis were reported. The DNA of the collected ticks was molecularly examined for infection with the family Anaplasmataceae. Twenty-six positive samples of Anaplasmataceae-specific PCR of partial 16S rRNA gene were subjected to semi-nested PCR, covering the divergent regions, the gene, and sequence analysis. Read More

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http://dx.doi.org/10.7883/yoken.JJID.2019.076DOI Listing
November 2019
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Seroprevalence of spp. and infections in horses: first report from Northern Bulgaria - Short communication.

Acta Vet Hung 2019 06;67(2):197-203

Department of Infectious Diseases, IDEXX Laboratories , Ludwigsburg , Germany.

Lyme borreliosis, granulocytic anaplasmosis and monocytic ehrlichiosis are well studied in humans and dogs. In horses, these diseases are not widely investigated and limited information is available about their occurrence. The purpose of this study was to present the first ELISA-based report on the seroprevalence of spp. Read More

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https://www.akademiai.com/doi/10.1556/004.2019.021
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http://dx.doi.org/10.1556/004.2019.021DOI Listing
June 2019
5 Reads

Natural Ehrlichia ruminantium infection in two captive Arabian tahrs (Arabitragus jayakari) in Oman.

Trop Anim Health Prod 2019 Nov 19;51(8):2539-2545. Epub 2019 Jun 19.

Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.

This study was investigated the cause of death of two captive adult Arabian tahrs (Arabitragus jayakari) died within 2-3 days after onset of fever and neurologic signs in a private farm in northern Batinah Region of Oman. Blood counting revealed leukocytosis attributed to neutrophilia and serum chemistry showed hypoproteinemia, increased creatine kinase and BUN. Upon autopsy, the animals exhibited mild ascites and hydrothorax, prominent hydropericardium, with large pale-yellow clear fluid coagulum, prominent epicardial petechiation, as well as severe pulmonary edema associated with frothy fluid in airways. Read More

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http://dx.doi.org/10.1007/s11250-019-01970-7DOI Listing
November 2019
25 Reads

Seroprevalence and risk factors associated with Ehrlichia canis in a hospital canine population.

Vet Clin Pathol 2019 Jun 9;48(2):305-309. Epub 2019 Jun 9.

Companion Animal Clinic (CAC-AUTh), School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Background: Ehrlichia canis (E canis) infection has been documented in a few small canine case series in Greece. However, there is limited information on the prevalence of exposure to, or the potential risk factors associated with E canis seroreactivity in a large native canine population.

Objectives: The objectives of this study were to evaluate E canis seroprevalence in dogs admitted to a veterinary teaching hospital, and to investigate the potential association between seropositivity and signalment, health status, the serologic assays used, and selected clinical and clinicopathologic abnormalities. Read More

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http://dx.doi.org/10.1111/vcp.12736DOI Listing
June 2019
21 Reads

Molecular detection and characterization of Anaplasma platys and Ehrlichia canis in dogs from northern Colombia.

Vet Microbiol 2019 Jun 4;233:184-189. Epub 2019 May 4.

Grupo de Investigación Evolución, Sistemática y Ecología Molecular (GIESEMOL), Universidad del Magdalena, Santa Marta, Magdalena, Colombia. Electronic address:

Ehrlichia canis and Anaplasma platys are intracellular tick-transmitted bacteria that infect dogs; there is evidence for limited zoonotic potential as well. The prevalence of E. canis in Colombia has been evaluated in different regions; however little is known about the prevalence or distribution of A. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.05.002DOI Listing
June 2019
5 Reads

Genetic diversity of Ehrlichia canis in dogs from Turkey inferred by TRP36 sequence analysis and phylogeny.

Comp Immunol Microbiol Infect Dis 2019 Jun 10;64:20-24. Epub 2019 Feb 10.

Department of Parasitology, College of Veterinary Medicine, Firat University, 23119, Elazig, Turkey.

Canine monocytic ehrlichiosis, an important tick-borne disease caused by Ehrlichia canis, is cosmopolitan but particularly prevalent in tropical and subtropical regions. In Turkey, the genetic diversity of E. canis remains undefined. Read More

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http://dx.doi.org/10.1016/j.cimid.2019.02.003DOI Listing
June 2019
3 Reads

Simultaneous infection of cattle with different Anaplasma phagocytophilum variants.

Ticks Tick Borne Dis 2019 08 30;10(5):1051-1056. Epub 2019 May 30.

Department of Medical Microbiology and Hygiene, University of Mainz, Obere Zahlbacherstrasse 67, D-55131, Mainz, Germany. Electronic address:

Anaplasma phagocytophilum is a tick-transmitted Gram-negative obligate intracellular bacterium that replicates in neutrophil granulocytes. It causes tick-borne fever in cattle and sheep. We report here the case of a 5-year-old cow from Germany with clinically overt granulocytic anaplasmosis presenting with fever, lower limb oedema and drop in milk-yield. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2019.05.011DOI Listing
August 2019
1 Read