90,580 results match your criteria Tibial Plateau Fracture Imagings


Structure and biomechanics of the antennal grooming mechanism in the southern green stink bug Nezara viridula.

J Insect Physiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Functional Morphology and Biomechanics, Kiel University, Germany.

Insects devote a high amount of time to self-groom to remove foreign material, especially from their sensory appendages. Using various microscopy techniques and behavioural experiments on intact and ablated insects, the present study investigates the antennal grooming of the green stinkbug Nezara viridula, which represents a serious pest of different crops in most areas of the world. The antennal grooming behaviour encompass an action of scraping involving the tibial comb complex (tibial comb + fossula) of both forelegs, generally followed by the tibial comb complex grooming of one leg using the tarsal hairy pad of the opposite leg (rubbing). Read More

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December 2018

[Postoperative functional angular anatomy in patients with anterior cruciate ligament with autologous graft].

Acta Ortop Mex 2018 May-Jun;32(3):157-162

Servicio de Cirugía Articular, Hospital Juárez de México, Ciudad de México.

Background: Reconstruction of the anterior cruciate ligament (ACL) aims to restore the original anatomy. The clinical outcome could be imperfect when graft placement is not in an anatomical position; moreover, the conventional transtibial reconstruction of the ACL often locates the graft away from the anatomical site, leading to abnormal biomechanical behavior and kinematics of the knee. The objective of this work was to assess the importance of the angular reconstruction of the anterior cruciate ligament during arthroscopic replacement and to compare the postoperative functional results. Read More

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December 2018

A laminin-derived functional peptide, PPFEGCIWN, promotes bone formation on sandblasted, large-grit, acid-etched titanium implant surfaces.

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

Purpose: This study aimed to investigate the in vitro and in vivo bone-forming potential of a sandblasted, large-grit, acid-etched (SLA) titanium (Ti) surface treated with a laminin-derived functional peptide, PPFEGCIWN (DN3).

Materials And Methods: Human osteoblast-like MG63 cells were cultured with SLA Ti discs untreated or treated with DN3 or a control scrambled peptide (SP). Cell adhesion, spreading, and viability on the discs were tested. Read More

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December 2018

Regenerated Bone Pattern Around Exposed Implants with Various Designs.

Int J Oral Maxillofac Implants 2018 Dec 5. Epub 2018 Dec 5.

Purpose: The design and surface features of dental implants substantially affect the healing and remodeling of adjacent bones. This study aimed to investigate the impact of design and surface on bone regeneration using implants of two different pitches, each with three different surface features.

Materials And Methods: Custom-manufactured titanium implants (length, 10 mm; diameter, 3. Read More

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December 2018
1 Read

Diffuse Tibiofemoral Cartilage Change Prior to the Development of Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative.

Clin Anat 2018 Dec 6. Epub 2018 Dec 6.

Division of Rheumatology, Allergy, and Immunology, Tufts Medical Center, Boston, MA, USA.

Introduction: We compared the spatial distribution of tibiofemoral cartilage change between individuals who will develop accelerated knee osteoarthritis (KOA) versus typical onset of KOA prior to the development of radiographic KOA.

Materials And Methods: We conducted a longitudinal case-control analysis of 129 individuals from the Osteoarthritis Initiative. We assessed the percent change in tibiofemoral cartilage on magnetic resonance images at 36 informative locations from two to one year prior to the development of accelerated (n=44) versus typical KOA (n=40). Read More

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December 2018

Effect of preservation methods on tensile properties of human femur-ACL-tibial complex (FATC) - a cadaveric study on male subjects.

Acta Bioeng Biomech 2018 ;20(4):31-42

Centre for Biomedical Engineering, Indian Institute of Technology (IIT) Delhi, New Delhi, India.

Purpose: Deep freezing and storing in formalin are some of the common techniques of human tissue preservation. However, the preservation modes affect the biomechanical properties of the tissues. In this work, the effects of the above-stated preservation tech- niques are compared with that of fresh cadaveric samples. Read More

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January 2018

Preliminary experience of the use of high-resolution skin ultrasound for the evaluation of extrathyroideal manifestations of Graves' disease and response to UVA-1 phototherapy.

Photodermatol Photoimmunol Photomed 2018 Dec 6. Epub 2018 Dec 6.

Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy.

Graves' orbitopathy (GO) and pre-tibial mixedema (PTM) are autoimmune manifestation sharing the same etiology and histopathology, a chronic course and a frustrating treatment. Current management include topical and systemic corticosteroid as first line therapy, whereas cyclosporine, surgery and orbital radiotherapy are indicated for severe GO with variable results and mostly temporary remissions. In particular, keratopath and photophobia, due to exophthalmos and eyelid retraction, impaired eye mobility and diplopia due to the compression of optic nerve and extra-ocular muscles are usually minimally modified, as well as leg plaques/nodules and lymphoedema. Read More

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December 2018
2 Reads

Microsurgical reconstruction with vascularized fibula and massive bone allograft for bone tumors.

Eur J Orthop Surg Traumatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Orthopaedic Surgery, IRCCS Istituto Ortopedico Rizzoli, via Pupilli n1, 40136, Bologna, Italy.

Introduction: Combining massive bone allograft and vascularized fibula in intercalary reconstruction following resection of bone tumors represents a complex reconstructive procedure that requires specialists in microvascular surgery as well as orthopedic surgery. The purpose of our study was to examine the outcomes using this surgical technique in patients with bone tumors in terms of oncologic results, complications related to surgery, Musculoskeletal Tumor Society (MSTS) scores and duration of surgery.

Materials And Methods: We analyzed 81 patients with femoral or tibial sarcomas who underwent intercalary resection and microsurgical reconstruction with massive bone allograft and vascularized fibula. Read More

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December 2018

Pressure Overload Impairs Cardiac Function in Long-Chain Fatty Acid Transporter CD36-Knockout Mice.

Int Heart J 2018 Dec 5. Epub 2018 Dec 5.

Rinku General Medical Center.

CD36 is one of the important transporters of long-chain fatty acids (LCFAs) in the myocardium. We previously reported that CD36-deficient patients demonstrate a marked reduction of myocardial uptake of LCFA, while myocardial glucose uptake shows a compensatory increase, and are often accompanied by cardiomyopathy. However, the molecular mechanisms and functional role of CD36 in the myocardium remain unknown. Read More

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December 2018
2 Reads

Intercalary allograft reconstruction in a patient with large tibial defect: Case report.

Injury 2018 Oct 16. Epub 2018 Oct 16.

Orthopaedic and Traumatology Division, Department of Medicine and Science of Aging, University of Study "G. d'Annunzio" Chieti-Pescara, Italy.

A fit 26 year-old-man presented to our Department with an open fracture of the left tibial shaft (AO 42-C3). The fracture was initially treated with an External Fixator, which was replaced by an intramedullary Grosse Kempf nail after 4 months. In the following year he developed an atrophic non-union and we witnessed the increasing bone resorption at the fracture site which led to the nail breakage. Read More

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October 2018
1 Read

Comparative study of the circumferential and volumetric analysis between conventional casting and three-dimensional scanning methods for transtibial socket: A preliminary study.

Proc Inst Mech Eng H 2018 Dec 6:954411918816124. Epub 2018 Dec 6.

1 Centre for Applied Biomechanics, Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.

Transtibial prosthetic sockets can be fabricated either by the conventional way, which involve using plaster of Paris bandages for casting. This will include modifications through hand, scanning and digital imaging of software. The aim of this study is to determine the circumferential profiles and conduct a volumetric analysis of a conventional socket that has fabrication using biosculptor technology. Read More

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December 2018

Mineral homeostasis in murine fetuses is sensitive to maternal calcitriol, but not to absence of fetal calcitriol.

J Bone Miner Res 2018 Dec 3. Epub 2018 Dec 3.

Faculty of Medicine - Endocrinology, Memorial University of Newfoundland, St. John's, NL, Canada.

Vitamin D receptor (VDR) null fetuses have normal serum minerals, PTH, skeletal morphology and mineralization, but increased serum calcitriol, placental calcium transport, and placental expression of Pthrp, Trpv6, and (as reported in this study) Pdia3. We examined Cyp27b1 null fetal mice, which do not make calcitriol, to determine if loss of calcitriol has the same consequences as loss of VDR. Cyp27b1 null and WT females were mated to Cyp27b1 males, which generated Cyp27b1 null and Cyp27b1 fetuses from Cyp27b1 null mothers, and Cyp27b1 and WT fetuses from WT mothers. Read More

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December 2018
1 Read

The utility of infrared thermography for evaluating lameness attributable to bacterial chondronecrosis with osteomyelitis.

Poult Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA.

Bacterial chondronecrosis with osteomyelitis (BCO) is a leading cause of lameness in broilers. Infrared thermography (IRT) is a noninvasive technique for measuring infrared radiation from an object and can be used to evaluate clinical health. Two replicated studies compared the effect of light intensity on broilers grown on a wire flooring model that experimentally increased their susceptibility to and incidence of BCO lameness. Read More

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December 2018

A Mouse Distraction Osteogenesis Model.

J Vis Exp 2018 Nov 14(141). Epub 2018 Nov 14.

Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine.

Distraction osteogenesis (DO) is a surgical procedure that involves skeletal tissue regeneration without cell transplantation. A DO model consists of the following three phases: the latency phase after osteotomy and placement of the external distractor; the distraction phase, wherein the separated bone ends are gradually and continuously distracted; and the consolidation phase. This custom-made distractor used for DO is comprised of two incomplete acrylic resin rings and an expansion screw. Read More

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November 2018

Data on a rat infection model to assess porous titanium implant coatings.

Data Brief 2018 Dec 2;21:1642-1648. Epub 2018 Nov 2.

Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands.

A model is needed to study the effectiveness of different anti-bacterial coatings on complex metal implants in a bone environment. This article shares data on the design of porous titanium implants for intramedullary implantation in the proximal rat tibia. The implant length, diameter and porosity were optimized after testing on cadaveric specimens. Read More

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December 2018

Feasibility of using a novel non-invasive ambulatory tibial nerve stimulation device for the home-based treatment of overactive bladder symptoms.

Transl Androl Urol 2018 Dec;7(6):912-919

Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology, London, UK.

Background: To evaluate safety, acceptability and pilot efficacy of transcutaneous low-frequency tibial nerve stimulation (TNS) using a novel device as home-based neuromodulation.

Methods: In this single-centre pilot study, 48 patients with overactive bladder (OAB) (24 with neurogenic and 24 with idiopathic OAB) were randomized to use a self-applicating ambulatory skin-adhering device stimulating transcutaneously the tibial nerve at 1 Hz for 30 minutes, either once daily or once weekly, for 12 weeks. Changes in OAB symptoms and QoL were measured at baseline, weeks 4, 8, and 12 using validated scoring instruments (ICIQ-OAB and ICIQ-LUTSqol), 3-day bladder diary and a Global Response Assessment (GRA) at week 12. Read More

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December 2018

No Difference between Extraction Drilling and Serial Dilation for Tibial Tunnel Preparation in Anterior Cruciate Ligament Reconstruction: A Systematic Review.

J ISAKOS 2018 May 25;3(3). Epub 2018 Jun 25.

University of Pittsburgh Medical Center, Center for Sports Medicine (Pittsburgh).

Importance: This review highlights a lack of consensus and need for further study regarding optimal tibial tunnel preparation method in anterior cruciate ligament reconstruction (ACLR).

Objective: This review examines existing clinical and biomechanical outcomes of both extraction drilling (ED) and serial dilation (SD) as a technique for tibial tunnel preparation in ACLR.

Evidence Review: In accordance with PRISMA guidelines, three electronic databases (MEDLINE, EMBASE, and PubMed) were searched and systematically screened in duplicate from database inception to September 6, 2017 for English-language, human studies, of all levels of evidence that examined ED and/or SD for tibial tunnel preparation in ACLR. Read More

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May 2018
1 Read

Factors Affecting Tibial Tuberosity-Trochlear Groove Distance in Recurrent Patellar Dislocation.

Clin Orthop Surg 2018 Dec 21;10(4):420-426. Epub 2018 Nov 21.

Center for Joint Disease, Chonnam National University Hwasun Hospital, Hwasun, Korea.

Background: The tibial tuberosity-trochlear groove (TT-TG) distance is used to determine the necessity of tibial tubercle osteotomy. We conducted this study to determine the extent to which each of the tibial tuberosity lateralization, trochlear groove medialization, and knee rotation angle affects the TT-TG distance in both normal and patella dislocated patients and thereby scrutinize the rationale for tuberosity transfer based on the TT-TG distance.

Methods: Retrospective analysis of rotational profile computed tomography was done for patella dislocated and control group patients. Read More

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December 2018
1 Read

Factors Affecting the Extent of Graft Tendon Synovialization after Double-Bundle Anterior Cruciate Ligament Reconstruction: Based on Second-Look Arthroscopic Findings.

Clin Orthop Surg 2018 Dec 21;10(4):413-419. Epub 2018 Nov 21.

Department of Orthopaedic Surgery, Pohang St. Mary's Hospital, Pohang, Korea.

Background: We aimed to examine the factors that influence synovialization of the grafted tendon after double-bundle anterior cruciate ligament (ACL) reconstruction based on second-look arthroscopic findings.

Methods: Out of 205 knees that were treated between August 2008 and May 2016 with double-bundle ACL reconstruction using bio-absorbable cross-pins and Endobuttons for femoral tunnel fixation, we enrolled 65 knees (64 patients) that underwent second-look arthroscopy with hardware removal at 1 year postoperatively. Measured clinical outcomes included the Lysholm score and Tegner activity score that were evaluated preoperatively and during the final follow-up. Read More

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December 2018

How to Avoid Graft-Tunnel Length Mismatch in Modified Transtibial Technique for Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Graft.

Clin Orthop Surg 2018 Dec 21;10(4):407-412. Epub 2018 Nov 21.

Department of Orthopedic Surgery, Yonsei Sarang Hospital, Seoul, Korea.

Background: We conducted this study to determine the optimal length of patellar and tibial bone blocks for the modified transtibial (TT) technique in anterior cruciate ligament (ACL) reconstruction using the bone-patellar tendon-bone (BPTB) graft.

Methods: The current single-center, retrospective study was conducted in a total of 64 patients with an ACL tear who underwent surgery at our medical institution between March 2015 and February 2016. After harvesting the BPTB graft, we measured its length and that of the patellar tendon, patellar bone block, and tibial bone block using the arthroscopic ruler and double-checked measurements using a length gauge. Read More

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December 2018

Using Tibia Proximal Cut Autograft in Advanced Varus Knee Deformity in Total Knee Arthroplasty; Outcomes Compared to the Control Group.

Authors:
Aydin Arslan

Open Orthop J 2018 24;12:405-410. Epub 2018 Oct 24.

Elit Istanbul Medical Center, Orthopaedics and Traumatology, Istanbul Gelisim university, Istanbul, Turkey.

Background: The purpose of this study was to compare the outcomes of Total Knee Arthroplasty (TKA) performed for advanced varus knee deformity, which is performed by using tibia proximal cut bone for the reconstruction of the tibia proximal medial bone defects, with a control group consisting of TKAs which did not need reconstruction.

Methods: Patients in the present study underwent total knee arthroplasty between 2009 and 2015. 12 patients with advanced varus deformity who had undergone reconstruction with tibia proximal cut autograft and 15 patients who were randomly selected from patients who did not need reconstruction, were compared clinically and radiographically. Read More

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October 2018
3 Reads

Adipofascial perforator flaps: Its role in reconstruction of soft-tissue defects of lower leg and ankle.

Indian J Plast Surg 2018 May-Aug;51(2):216-221

Department of Burns, Plastic and Maxillofacial Surgery, Safdarjung Hospital and VMMC, New Delhi, India.

Background: Despite advances in surgical skills, adipofascial flaps are still less preferred option for coverage of leg defect. We evaluate the use of perforator-based adipofascial flap in small-to-medium-sized soft-tissue defects in the lower limb.

Patients And Methods: After localisation of perforators along the major axial vessels in the lower limb using handheld Doppler, adipofascial flap based on the nearest best perforator of anterior tibial artery, posterior tibial artery and peroneal artery was raised to cover soft-tissue defect in 21 patients. Read More

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December 2018

Comparison of bone texture between normal individuals and patients with Kashin-Beck disease from plain radiographs in knee.

Sci Rep 2018 Nov 30;8(1):17510. Epub 2018 Nov 30.

Department of Integrative Molecular Biology, Umeå University, 90187, Umeå, Sweden.

To compare tibial bone texture between Kashin-Beck disease (KBD) patients and normal individuals from plain radiographs using an advanced image analysis. Plain knee radiographs were obtained from KBD patients (n = 49) and age-matched healthy controls (n = 98). KBD were graded with diagnostic criteria WS/T 207-2010. Read More

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November 2018
2 Reads

Progressive Sublesional Bone Loss Extends into the Second Decade After Spinal Cord Injury.

J Clin Densitom 2018 Oct 31. Epub 2018 Oct 31.

Department of Veterans Affairs Rehabilitation Research & Development Service National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA; Departments of Medicine and Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Objective: The rate of areal bone mineral density (aBMD) loss at the knee (distal femur (DF) and proximal tibia ) and hip (femoral neck (FN) and total hip (TH)) was determined in persons with traumatic spinal cord injury (SCI) who were stratified into subgroups based on time since injury (TSI).

Design: Cross-sectional retrospective review.

Setting: Department of Veterans Affairs Medical Center and Private Rehabilitation Hospital. Read More

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October 2018
1 Read

Complications Associated With Medial Opening-Wedge High Tibial Osteotomy Using a Locking Plate: A Multicenter Study.

J Arthroplasty 2018 Nov 14. Epub 2018 Nov 14.

Department of Orthopaedic Surgery, Korea University Anam Hospital, Korea University School of Medicine, Seoul, South Korea.

Background: The aim of this study is to investigate complications following medial opening-wedge high tibial osteotomy using a locking plate. In addition, we aimed to compare postoperative outcomes between the complicated and the uncomplicated group.

Methods: This study enrolled 209 patients who underwent medial opening-wedge high tibial osteotomy between 2010 and 2015. Read More

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November 2018

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study.

Lancet Diabetes Endocrinol 2018 Nov 28. Epub 2018 Nov 28.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Orthopedic Surgery, Harvard Medical School, Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Background: Although areal bone mineral density (aBMD) assessed by dual-energy x-ray absorptiometry (DXA) is the clinical standard for determining fracture risk, most older adults who sustain a fracture have T scores greater than -2·5 and thus do not meet the clinical criteria for osteoporosis. Importantly, bone fragility is due to low BMD and deterioration in bone structure. We assessed whether indices of high-resolution peripheral quantitative CT (HR-pQCT) were associated with fracture risk independently of femoral neck aBMD and the Fracture Risk Assessment Tool (FRAX) score. Read More

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November 2018

Radiographic Assessment of the Popliteal Lymph Node to Aid the Differentiation of Canine Stifle Osteosarcoma From Moderate to Severe Stifle Degenerative Joint Disease.

Top Companion Anim Med 2018 Dec 20;33(4):136-140. Epub 2018 Aug 20.

Department of Veterinary Clinical Sciences, Ohio State University College of Veterinary Medicine, Columbus, OH, USA. Electronic address:

Degenerative joint disease of the stifle is a common canine osseous pathology. Early degenerative changes may show mild mineral proliferation of periarticular margins with soft tissue, resulting in joint distension. If the joint is chronically unstable, osseous changes become more complex. Read More

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December 2018

Interrelationship of cartilage composition and chondrocyte mechanics after a partial meniscectomy in the rabbit knee joint - Experimental and numerical analysis.

J Biomech 2018 Nov 19. Epub 2018 Nov 19.

Department of Applied Physics, University of Eastern Finland, Kuopio FI-70211, Finland.

Site-specific and depth-dependent properties of cartilage were implemented within a finite element (FE) model to determine if compositional or structural changes in the tissue could explain site-specific alterations of chondrocyte deformations due to cartilage loading in rabbit knee joints 3 days after a partial meniscectomy (PM). Depth-dependent proteoglycan (PG) content, collagen content and collagen orientation in the cartilage extracellular matrix (ECM), and PG content in the pericellular matrix (PCM) were assessed with microscopic and spectroscopic methods. Patellar, femoral groove and samples from both the lateral and medial compartments of the femoral condyle and tibial plateau were extracted from healthy controls and from the partial meniscectomy group. Read More

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November 2018

IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice.

J Neuroinflammation 2018 Nov 30;15(1):332. Epub 2018 Nov 30.

Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu, 210029, People's Republic of China.

Background: Perioperative neurocognitive disorders (PND) occur frequently after surgery, especially in aged patients. Surgery-induced neuroinflammation and blood-brain barrier (BBB) dysfunction play a crucial role in the pathogenesis of PND. Interleukin-17A (IL-17A) increases after surgical stress and will be involved in BBB dysfunction. Read More

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November 2018

The diagnosis and treatment of tibial intercondylar chondroblastoma.

Clinics (Sao Paulo) 2018 Nov 29;73:e540. Epub 2018 Nov 29.

Emergency Department, Second Affiliated Hospital of the Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310090.

Objectives: To investigate the diagnosis and treatment of tibial intercondylar chondroblastoma.

Methods: We retrospectively analyzed the diagnosis and treatment of 12 patients with tibial intercondylar chondroblastoma admitted to the orthopedics department from May 2011 to February 2016; among them were 4 males and 3 females aged 10-19 years, with an average age of 15.7 years. Read More

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November 2018
2 Reads

Cranio-caudal and medio-lateral navicular translation are representative surrogate measures of foot function in asymptomatic adults during walking.

PLoS One 2018 5;13(12):e0208175. Epub 2018 Dec 5.

Bern University of Applied Sciences, Department of Health Professions, Division of Physiotherapy, Bern, Switzerland.

Introduction: The translation of the navicular bone is thought to be a representative surrogate measure to assess foot pronation and hence foot function; however, it is not known how it is related to multi-segment foot kinematics.

Methods: Cranio-caudal (NCC) and medio-lateral (NML) navicular translation and multi-segment foot kinematics from the Oxford Foot Model (OFM) were simultaneously assessed during the stance phase of walking in 20 healthy adults. Relationships to forefoot to hindfoot (FFtoHF), hindfoot to tibia (HFtoTBA) and global hindfoot (HFL) motion were explored by cross-correlations at zero phase shift. Read More

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December 2018
1 Read

Three-dimensional kinematic corridors of the head, spine, and pelvis for small female driver seat occupants in near- and far-side oblique frontal impacts.

Traffic Inj Prev 2018 Dec 5:1-6. Epub 2018 Dec 5.

a Department of Neurosurgery , Medical College of Wisconsin , Milwaukee , Wisconsin.

Objectives: Analyses of recent automotive accident data indicate an increased risk of injury for small female occupants compared to males in similar accidents. Females have been shown to be more susceptible to spinal injuries than males. To protect this more vulnerable population, advanced anthropomorphic test devices (ATDs) and computer human body models are being developed and require biofidelity curves for validation. Read More

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December 2018
2 Reads

Is tranexamic acid safe and reliable during tibial intramedullary nailing?

Ulus Travma Acil Cerrahi Derg 2018 Nov;24(6):575-580

Department of Orthopedics and Traumatology, Health Sciences University Ümraniye and Training and Research Hospital, İstanbul-Turkey.

Background: The aim of this study was to determine if the use of tranexamic acid (TXA) during intramedullary reaming treatment for tibial diaphyseal fractures was safe, reduced blood loss, or affected cost effectiveness.

Methods: A total of 70 patients with a tibia diaphysis fracture were randomized into 2 groups and prospectively followed for data on blood loss, thrombosis, and fracture healing. Preoperative TXA was administered intravenously to Group A, and Group B served as the control group. Read More

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November 2018

[Autogenous distal tibial cancellous bone graft with periosteum for the treatment of cartilage injury of talus with Hepple III-IV type].

Zhongguo Gu Shang 2018 Nov;31(11):1061-1064

Department of Orthopaedics, Luannan County Hospital, Tangshan 063000, Hebei, China;

Objective: To analyze the operative methods and clinical effects of autologous distal tibial cancellous bone graft with periosteum in treating cartilage injury of talus with Hepple III-IV type.

Methods: From June 2014 to August 2017, 25 patients (25 feet) with Hepple III to IV cartilage injury of talus were treated with autogenous ipsilateral distal tibial cancellous bone graft. Including 14 males and 11 females, aged from 18 to 52 years with an average of (38. Read More

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November 2018

Surgery for urinary incontinence in women: Report from the 6th international consultation on incontinence.

Neurourol Urodyn 2018 Dec 4. Epub 2018 Dec 4.

Department of Urology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.

Urinary incontinence is a prevalent condition worldwide and causes a tremendous impact on a woman's quality of life. While conservative and non-surgical therapies are options for treatment, surgery for stress urinary incontinence (SUI) is common. Options include colposuspension, slings (pubovaginal and midurethral), and periurethral bulking. Read More

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December 2018
1 Read

Upward running is more beneficial than level surface or downslope running in reverting tibia bone degeneration in ovariectomized rats.

J Musculoskelet Neuronal Interact 2018 Dec;18(4):493-500

Department of Physical Therapy, Niigata University of Health and Welfare, Japan.

Objective: We investigated the effects of upslope, level surface, and downslope running on indices of tibia and femur bone recovery in ovariectomized (OVX) rats.

Methods: Rats were randomly divided into five groups: one sham-operated (SHAM) group and four OVX groups. One OVX group was a non-running control (OVX-Cont) and the others performed upslope running (OVX-Up), level surface running (OVX-Level), or downslope running (OVX-Down) on a treadmill after ovariectomy. Read More

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December 2018

Torsion - an underestimated form shaping entity in bone adaptation?

J Musculoskelet Neuronal Interact 2018 Dec;18(4):407-418

German Aerospace Center, Institute for Aerospace Medicine, Germany.

Objectives: There is ample agreement that the specific shape of a bone is related to the loads it has to carry. It is also believed that bones mechano-adapt in order to 'find' this shape. The open question is which signals constitute the determinants of this adapation. Read More

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December 2018

Cost-effectiveness of overactive bladder treatments: from the US payer perspective.

J Comp Eff Res 2018 Dec 4. Epub 2018 Dec 4.

Department of Urology, Mount Sinai Hospital, 625 Madison Avenue, New York, NY, 10022, USA.

Aim: To assess the cost-effectiveness of onabotulinumtoxinA (onabotA), implantable sacral nerve stimulation devices, percutaneous tibial nerve stimulation, anticholinergic medications and mirabegron compared with best supportive care (BSC) for management of refractory overactive bladder (OAB).

Methods: A Markov model was developed to compare the cost-effectiveness of treatment options with BSC over a 10-year time horizon. Resource utilization, discontinuation rates and costs were derived from unpublished and published sources. Read More

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December 2018

The Role of Circular Frames in the Management of Tibial Fractures.

Cureus 2018 Sep 25;10(9):e3356. Epub 2018 Sep 25.

Orthopaedics, University Hospital Galway, Galway, IRL.

Introduction The purpose of this study is to evaluate the factors that impact the clinical and radiographic outcomes in a patient cohort undergoing external fixation for tibial fractures. We also aim to investigate the use of autograft, allograft, and synthetic bone graft in varying combinations in the setting of tibial bone loss with respect to optimal times to union. Methods This was a retrospective study, including 46 patients treated with a circular external fixator for the management of acute tibial fractures. Read More

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September 2018
2 Reads

Predictive factors for satisfaction after contemporary unicompartmental knee arthroplasty and high tibial osteotomy in isolated medial femorotibial osteoarthritis.

Orthop Traumatol Surg Res 2018 Nov 30. Epub 2018 Nov 30.

Department of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, 06591 Seoul, Republic of Korea; Department of Orthopaedic Surgery, Seoul St. Mary's Hospital, 06591 Seoul, Republic of Korea. Electronic address:

Introduction: Both high tibial osteotomy (HTO) and unicompartmental knee arthroplasty (UKA) are viable treatment options for early osteoarthritis (OA). Although a substantial proportion of the patient selection criteria for HTO and UKA are now shared, the factors related to satisfaction following each procedure remain unclear.

Hypothesis: We hypothesized that patient factors associated with satisfaction following contemporary HTO and UKA would be different. Read More

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November 2018

Editorial Commentary: Lateral Hinge Fracture After Opening Wedge High Tibial Osteotomy With Long Locking Plate Use.

Authors:
Jae Gyoon Kim

Arthroscopy 2018 Dec;34(12):3256-3257

Korea University College of Medicine.

Lateral hinge fracture (LHF) is a common complication after opening wedge high tibial osteotomy. Such a fracture can be caused by many factors such as osteotomy level, amount of opening, hinge position, and kind of plate. In particular, long locking plates have superior biomechanical stability in cases of LHF compared with short plates. Read More

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December 2018

3-D wound scanner: A novel, effective, reliable, and convenient tool for measuring scar area.

Burns 2018 Dec 25;44(8):1930-1939. Epub 2018 Oct 25.

Department of Burn Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China. Electronic address:

This study aimed to investigate whether a three-dimensional (3-D) wound scanner could be used to measure the area of scars. Scar models were constructed using flesh-colored, brown-colored (simulating hyperpigmented scars), orange-colored (simulating scars with obvious vascularization), and white-colored (simulating hypopigmented scars) plastic. Each colored plastic was used to construct scar models with regular and irregular base surfaces (four each). Read More

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December 2018
4 Reads

Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouse.

J Neuroinflammation 2018 Dec 3;15(1):335. Epub 2018 Dec 3.

János Szentágothai Research Centre, Molecular Pharmacology Research Team and Centre for Neuroscience, University of Pécs, Pécs, Hungary.

Objective: The regulatory role of capsaicin-sensitive peptidergic sensory nerves has been shown in acute inflammation, but little is known about their involvement in T/B-cell driven autoimmune arthritis. This study integratively characterized the function of these nerve endings in the proteoglycan-induced chronic arthritis (PGIA), a translational model of rheumatoid arthritis.

Methods: Peptidergic afferents were defunctionalized by resiniferatoxin (RTX) pretreatment in BALB/c mice, PGIA was induced by repeated antigen challenges. Read More

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December 2018
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Improvement of bone microarchitecture parameters after 12 months of treatment with asfotase alfa in adult patient with hypophosphatasia: Case report.

Medicine (Baltimore) 2018 Nov;97(48):e13210

Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Rationale: Hypophosphatasia is an inborn error of metabolism that can appear any time in life, mainly with bone manifestations due to low alkaline phosphatase activity. Asfotase alfa is a specific enzyme reposition treatment that has shown promising results in children; however, there are few reports about the outcomes in adult patients.

Patient Concerns: A 36-year-old male presented with an early history of craniosynostosis, short stature, and multiple fractures since the age of 13 years-which needed numerous surgical corrections. Read More

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November 2018
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The mechanical performance of cementless total knee replacements: it's not all about the maximum loads.

J Orthop Res 2018 Nov 30. Epub 2018 Nov 30.

Hospital for Special Surgery, New York, NY, USA.

Finite element (FE) models are frequently used to assess mechanical interactions between orthopaedic implants and surrounding bone. However, FE studies are often limited by: the small number of bones that are modeled; the use of normal bones that do not reflect the altered bone density distributions that result from osteoarthritis (OA); and the application of simplified load cases usually based on peak forces and without consideration of tibiofemoral kinematics. To overcome these limitations, we undertook an integrated approach to determine the most critical scenario for the interaction between an uncemented tibial component and surrounding proximal tibial bone. Read More

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November 2018

Tibial Nerve Palsy After Lateralizing Calcaneal Osteotomy.

Foot Ankle Spec 2018 Nov 30:1938640018816363. Epub 2018 Nov 30.

Section for Foot and Ankle Surgery, Division of Orthopaedic Surgery, Oslo University Hospital, Oslo, Norway.

Background: Lateralizing calcaneal osteotomy (LCO) is a common procedure used to correct hindfoot varus. Several complications have been described in the literature, but only a few articles describe tibial nerve palsy after this procedure. Our hypothesis was that tibial nerve palsy is a common complication after LCO. Read More

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November 2018
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The assessment of the stability of the tibial component of a novel knee arthroplasty system using radiostereometric analysis.

Bone Joint J 2018 Dec;100-B(12):1579-1584

Division of Orthopaedics, Department of Surgery, QEII Health Sciences Centre, Halifax, Canada; Dalhousie University, Halifax, Canada.

Aims: The introduction of a novel design of total knee arthroplasty (TKA) must achieve outcomes at least as good as existing designs. A novel design of TKA with a reducing radius of the femoral component and a modified cam-post articulation has been released and requires assessment of the fixation to bone. Radiostereometric analysis (RSA) of the components within the first two postoperative years has been shown to be predictive of medium- to long-term fixation. Read More

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December 2018