636 results match your criteria Thyrotoxicosis Imaging


Hypercalcaemic Crisis Due to Primary Hyperparathyroidism: Report of Two Cases.

J Crit Care Med (Targu Mures) 2019 Jan 4;5(1):34-39. Epub 2019 Feb 4.

University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureş, Romania.

Introduction: A hypercalcaemic crisis, also called para thyrotoxicosis, hyper parathyroid crisis or parathyroid storm, is a complication of primary hyperparathyroidism (PHPT) and an endocrinology emergency that can have dramatic or even fatal consequences if it is not recognised and treated in time.

Case Presentation: Two cases presented in the emergency department with critical hypercalcaemic symptoms and severe elevation of serum calcium and parathyroid hormone levels, consistent with a hypercalcaemic crisis. The first case, a 16-year-old female patient, had imaging data that highlighted a single right inferior parathyroid adenoma and a targeted surgical approach was used. Read More

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http://dx.doi.org/10.2478/jccm-2019-0004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369571PMC
January 2019

Plurihormonal Pituitary Tumor of Pit-1 and SF-1 Lineages, with Synchronous Collision Corticotroph Tumor: a Possible Stem Cell Phenomenon.

Endocr Pathol 2019 Jan 4. Epub 2019 Jan 4.

Department of Pathology, Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.

Thyrotropin (TSH)-secreting pituitary tumors are the rarest functioning pituitary tumors. Nonetheless, they are not infrequently plurihormonal, as they may express/secrete hormones made by other pituitary cells derived from the Pit-1 lineage such as growth hormone (GH), prolactin (PRL), and α-subunit (αSU). However, adrenocorticotropin (ACTH) or gonadotropin secretion by such a tumor is exceptional. Read More

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http://dx.doi.org/10.1007/s12022-018-9562-3DOI Listing
January 2019
1 Read

[An enlarged thymus associated with Graves' disease].

Ned Tijdschr Geneeskd 2018 Jul 20;162. Epub 2018 Jul 20.

Scheper Ziekenhuis, afd. Endocrinologie, Emmen.

Background: Thyrotoxicosis and orbitopathy are the best-known expressions of Graves' disease. There are also rarer and less-known phenomena, such as thymic hyperplasia. Identification of these is important in order to avoid potentially unnecessary invasive interventions. Read More

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July 2018
3 Reads

Amiodarone-Induced Thyrotoxicosis: Differential Diagnosis Using 99mTc-SestaMIBI and Target-to-Background Ratio (TBR).

Clin Nucl Med 2018 Sep;43(9):655-662

From the Department of Medicine (DIMED), Endocrinology Unit, and.

Purpose Of The Report: Distinguishing between amiodarone-induced thyrotoxicosis (AIT) caused by excessive hormone synthesis (AIT-1) or by a destructive process (AIT-2) has important therapeutic implications, but is still difficult and debated. Tc-sestaMIBI thyroid scintigraphy (99m-STS) has been proposed as a tool for classifying the two forms.

Material And Methods: 30 AIT patients (11 females and 19 males) who underwent 99m-STS were retrospectively assessed for the present study. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002207DOI Listing
September 2018
12 Reads

Unexpected cause of fever in a patient with untreated HIV.

BMJ Case Rep 2018 Jul 3;2018. Epub 2018 Jul 3.

Department of Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

We report a case of a 27-year-old man with a history of untreated HIV who presented with fever, rash and leg cramps. Initial suspicion was high for an infectious process; however, after an exhaustive evaluation, thyrotoxicosis was revealed as the aetiology of his symptoms. Recent intravenous contrast administration complicated his workup to determine the exact cause of hyperthyroidism. Read More

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http://dx.doi.org/10.1136/bcr-2018-225087DOI Listing
July 2018
21 Reads

Radioiodine (I) therapies performed in a paediatric hospital: facilities and procedures.

Australas Phys Eng Sci Med 2018 Sep 25;41(3):747-756. Epub 2018 Jun 25.

Nuclear Medicine, SA Medical Imaging, Women's and Children's Hospital, 72 King William Road, North Adelaide, SA, 5006, Australia.

Radioiodine (I) therapies on younger children with thyroid cancer and neuroblastoma can be challenging as they are required to be isolated for a period of time due to radiation safety concerns. At our hospital these therapies are performed in a purpose-built child-friendly therapy room. Nursing staff are able to provide personal care during the isolation period with minimum radiation exposure. Read More

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http://dx.doi.org/10.1007/s13246-018-0658-3DOI Listing
September 2018
2 Reads

Transient Hyperthyroidism Induced by Thyroid Ultrasound.

Ann Otol Rhinol Laryngol 2018 Aug 17;127(8):558-562. Epub 2018 Jun 17.

1 Section of Endocrinology and Metabolism, Department of Internal Medicine, Louisiana State University Health Sciences Center in Shreveport, Shreveport, Louisiana, USA.

Objectives: Transient hyperthyroidism has been documented following surgical manipulation or direct trauma to the normal thyroid gland. This has best been studied in patients following parathyroidectomy and also reported following trauma to the neck, strangulation, and vigorous palpation of the thyroid gland. It has not previously been reported following a thyroid ultrasound. Read More

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http://dx.doi.org/10.1177/0003489418781169DOI Listing
August 2018
21 Reads

Case report of recurrent atrial fibrillation induced by thyrotropin-secreting pituitary adenoma with Graves' disease.

Medicine (Baltimore) 2018 Jun;97(24):e11047

Department of Endocrinology and Metabolism.

Rationale: Thyrotropin-secreting adenoma (TSHoma) is rare. Even though the thyrotoxicosis is mild in patients with TSHoma, it is still a rare cause of arrhythmia, ignore of mild disfunction of thyroid function of TSHoma can lead to the delayed diagnosis of pituitary tumor or leading to recurring of complications. Graves' disease is an auto-immue endocrinological disorder. Read More

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http://dx.doi.org/10.1097/MD.0000000000011047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023673PMC
June 2018
3 Reads

Management of thyroid gland abscess.

Acta Otorrinolaringol Esp 2018 Jun 8. Epub 2018 Jun 8.

Servicio de Otorrinolaringología, Hospital Clínico Universitario de Valencia, Valencia, España.

Background: Thyroid abscess or acute suppurative thyroiditis is an unusual clinical condition. We present our experience with cases attended over 41 years.

Materials And Methods: A retrospective study was performed on these patients reviewing their epidemiological characteristics and the diagnostic and therapeutic manoeuvres chosen for them all, as well as their clinical outcome. Read More

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http://dx.doi.org/10.1016/j.otorri.2018.01.005DOI Listing
June 2018
16 Reads

Unusual case of anti-N-methyl-D-aspartic acid-receptor (NMDA-R) encephalitis and autoimmune polyglandular syndrome (APS).

BMJ Case Rep 2018 May 2;2018. Epub 2018 May 2.

Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland Medical Center, Baltimore, Maryland, USA.

Anti-N-methyl-D-aspartic acid-receptor (NMDA-R) encephalitis is a novel disease discovered within the past 10 years. It is an autoimmune disease (AD) that has been associated with other ADs, such as Graves' disease. However, association with autoimmune polyglandular syndromes (APS) has not been previously described. Read More

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http://dx.doi.org/10.1136/bcr-2018-224821DOI Listing
May 2018
15 Reads

A case of TSH-secreting pituitary adenoma with cyclic fluctuations in serum TSH levels.

Endocr J 2018 Jul 26;65(7):737-746. Epub 2018 Apr 26.

Department of Molecular Endocrinology and Metabolism, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.

A 29-year-old man was referred to our department due to adrenal insufficiency with the inappropriate secretion of TSH (SITSH). Magnetic resonance imaging revealed a pituitary tumor. A weak TSH response in the TRH test, elevated sex hormone binding globulin (SHBG) levels, and the absence of a family medical history of SITSH or TRβ gene mutations supported the diagnosis of TSH-secreting pituitary adenoma (TSHoma). Read More

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http://dx.doi.org/10.1507/endocrj.EJ18-0006DOI Listing
July 2018
8 Reads

Role of Diffusion-Weighted Magnetic Resonance (MR) Imaging in Differentiation Between Graves' Disease and Painless Thyroiditis.

Pol J Radiol 2017 15;82:536-541. Epub 2017 Sep 15.

Department of Internal Medicine, Mansoura Faculty of Medicine, Mansoura, Egypt.

Background: To assess the role of diffusion-weighted MR imaging in differentiation between Graves' disease and painless thyroiditis.

Material/methods: A prospective study was conducted among 37 consecutive patients with untreated thyrotoxicosis (25 female and 12 male; mean age of 44 years) and 15 ageand sex-matched controls. Diffusion-weighted MR imaging of the thyroid gland was performed in patients and controls. Read More

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http://dx.doi.org/10.12659/PJR.902416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894041PMC
September 2017
2 Reads

Amiodarone-Induced Thyroid Dysfunction: A Clinical Update.

Exp Clin Endocrinol Diabetes 2018 Jun 20;126(6):333-341. Epub 2018 Mar 20.

Department of Endocrinology, Diabetes & Metabolism, University Hospitals of Morecambe Bay NHS Foundation Trust, United Kingdom, LA1 4RP.

Amiodarone is one of the most commonly prescribed antiarrhythmic agents in clinical practice owing to its efficacy, even with high toxicity profile. The high iodine content and the prolonged biological half-life of the drug can result in thyroid dysfunction in a high proportion of patients treated with amiodarone even after cessation of amiodarone. Both hypothyroidism and hyperthyroidism are common side effects that mandate regular monitoring of patients with thyroid function tests. Read More

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http://dx.doi.org/10.1055/a-0577-7574DOI Listing
June 2018
3 Reads

Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm.

Intern Med 2018 Jul 28;57(13):1939-1942. Epub 2018 Feb 28.

Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan.

We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves' disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine and a decreased plasma vasopressin level. Read More

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http://dx.doi.org/10.2169/internalmedicine.0063-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064704PMC
July 2018
11 Reads

Thyrotoxicosis and Adrenocortical Hormone Deficiency During Immune-checkpoint Inhibitor Treatment for Malignant Melanoma.

In Vivo 2018 Mar-Apr;32(2):345-351

The First Department of Medicine, Wakayama Medical University, Wakayama, Japan.

Background: Immune-checkpoint inhibitors (ICIs) are novel promising agents for the treatment of malignant tumors. However, critical endocrine immune-related adverse events (irAEs) by ICIs often occur.

Case Report: A 63-year-old woman with advanced malignant melanoma had received anti-PD-1 antibody (nivolumab, 2 mg/kg every 3 weeks) for 8 cycles (from day 0 to day 147). Read More

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http://dx.doi.org/10.21873/invivo.11244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905204PMC
August 2018
6 Reads

Asymptomatic thyroiditis presenting as pyrexia of unknown origin: a case report.

Authors:
Chamara Dalugama

J Med Case Rep 2018 Feb 23;12(1):51. Epub 2018 Feb 23.

Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

Background: Pyrexia of unknown origin is a difficult and challenging problem for the physician. Endocrine disorders, such as subacute thyroiditis, rarely present with pyrexia of unknown origin. Subacute thyroiditis can have a broad spectrum of clinical presentations including fever and biochemical thyrotoxicosis without overt signs or symptoms. Read More

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http://dx.doi.org/10.1186/s13256-018-1590-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824559PMC
February 2018
6 Reads

A thyroid storm patient with protracted disturbance of consciousness and reversible lesion in the splenium of corpus callosum: A case report.

Medicine (Baltimore) 2018 Feb;97(7):e9949

Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Johnan-cho, Hitachi, Ibaraki, Japan.

Rationale: Various neurological manifestations are observed in thyroid storm patients but protracted disturbance of consciousness is rare.

Patient Concerns: A 58-year-old male was admitted to our hospital after a traffic accident.

Diagnoses: Although awake on arrival, he fell into coma after admission. Read More

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http://dx.doi.org/10.1097/MD.0000000000009949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839822PMC
February 2018
10 Reads

Ectopic thyrotropin secreting pituitary adenoma concomitant with papillary thyroid carcinoma: Case report.

Medicine (Baltimore) 2017 Dec;96(50):e8912

Department of Endocrinology.

Rationale: Ectopic thyrotropin (TSH)-secreting pituitary adenomas are exceedingly rare. To date, there are only 6 cases reported. Here, we describe an even rarer ectopic TSH-secreting pituitary adenoma (TSH-oma) concomitant with papillary thyroid carcinoma. Read More

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http://Insights.ovid.com/crossref?an=00005792-201712150-0002
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000008912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815691PMC
December 2017
4 Reads

Thyrotoxic Neuropathy: A rare cause of acute flaccid paraplegia.

Sultan Qaboos Univ Med J 2017 Nov 10;17(4):e460-e463. Epub 2018 Jan 10.

Department of Neurology, Royal Hospital, Muscat, Oman.

Acute polyneuropathy is a rare manifestation of severe hyperthyroidism. We report a 22-year-old Omani male who presented to the Sohar Hospital, Sohar, Oman, in 2016 with acute-onset rapidly progressive flaccid areflexic paraplegia as the presenting manifestation of thyrotoxicosis. Nerve conduction studies revealed mixed axonal and demyelinating polyneuropathy in both the motor and sensory nerves. Read More

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http://dx.doi.org/10.18295/squmj.2017.17.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766304PMC
November 2017
6 Reads

Anaplastic thyroid carcinoma with rapid thyrotoxicosis - a case report and the literature review.

Endokrynol Pol 2018 10;69(1):28-31. Epub 2018 Jan 10.

Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University.

Introduction: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies and constitutes approximately 1.6-5% of the malignant neoplasms of the thyroid gland. ATC usually manifests itself with the local symptoms due to a rapidly enlarging thyroid mass, and as other thyroid cancers, has only seldom been reported to cause thyrotoxicosis. Read More

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http://dx.doi.org/10.5603/EP.a2018.0010DOI Listing
July 2018
13 Reads

Stroke in a Young Man Secondary to Paroxysmal Atrial Fibrillation and Thyrotoxicosis: A Case Report.

Case Rep Neurol 2017 Sep-Dec;9(3):228-233. Epub 2017 Oct 16.

Department of Internal Medicine, Botucatu School of Medicine, Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil.

We report a case of a male patient with stroke caused by atrial fibrillation (AF) due to thyrotoxicosis. At hospital admission, he presented hypertension and AF. Magnetic resonance imaging confirmed a right-side ischemic area. Read More

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http://dx.doi.org/10.1159/000479730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731184PMC
October 2017
4 Reads

Puzzling thyroid function test.

BMJ Case Rep 2017 Nov 27;2017. Epub 2017 Nov 27.

Institute of Metabolic Science, University of Cambridge, Cambridge, UK.

A 13-½-year-old boy was referred to the Department of Endocrinology as a case of thyrotoxicosis for initiation of antithyroid medication. His chief complaint was a swelling in front of the neck, which was incidentally noted by his mother 2 weeks prior to presentation. He denied any history of symptoms suggestive of hyperthyroidism or ophthalmological involvement. Read More

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http://dx.doi.org/10.1136/bcr-2017-222712DOI Listing
November 2017
7 Reads

Iodinated Contrast Administration Resulting in Cardiogenic Shock in Patient with Uncontrolled Graves Disease.

J Emerg Med 2017 Dec 6;53(6):e125-e128. Epub 2017 Nov 6.

Virginia Tech Carilion Emergency Medicine Residency, Department of Emergency Medicine, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.

Background: Thyroid storm (also known as thyroid or thyrotoxic crisis) is part of the spectrum of thyrotoxicosis and represents the extreme end of that spectrum. The condition is quite rare, yet mortality rates are high and may approach 10-30%.

Case Report: A 34-year-old-man who had a history of Graves disease presented in atrial fibrillation with rapid ventricular response and mild congestive heart failure. Read More

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http://dx.doi.org/10.1016/j.jemermed.2017.08.096DOI Listing
December 2017
7 Reads

Bone marrow failure and extramedullary hematopoiesis in McCune-Albright syndrome.

Osteoporos Int 2018 01 25;29(1):237-241. Epub 2017 Oct 25.

Section on Skeletal Disorders and Mineral Homeostasis, Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

In fibrous dysplasia/McCune-Albright syndrome (FD/MAS), bone and bone marrow are, to varying degrees, replaced by fibro-osseous tissue typically devoid of hematopoietic marrow. Despite the extensive marrow replacement in severely affected patients, bone marrow failure is not commonly associated with FD/MAS. We present a 14-year-old girl with FD/MAS, who developed pancytopenia and extramedullary hematopoiesis (EMH) with no identified cause, in the setting of iatrogenic thyrotoxicosis and hyperparathyroidism. Read More

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http://dx.doi.org/10.1007/s00198-017-4217-7DOI Listing
January 2018
4 Reads

Clinical characteristics of hypertensive encephalopathy in pediatric patients.

Korean J Pediatr 2017 Aug 14;60(8):266-271. Epub 2017 Aug 14.

Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea.

Purpose: The aim of this study was to assess the clinical characteristics of hypertensive encephalopathy according to the underlying etiologies in children.

Methods: We retrospectively evaluated 33 pediatric patients who were diagnosed as having hypertensive encephalopathy in Chonbuk National University Children's Hospital. Among the patients, 18 were excluded because of incomplete data or because brain magnetic resonance imaging (MRI) was not performed. Read More

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http://dx.doi.org/10.3345/kjp.2017.60.8.266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638725PMC
August 2017
14 Reads

Molecular radiotheragnostics in thyroid disease.

Clin Med (Lond) 2017 Oct;17(5):453-457

Kings College London, London, UK.

Molecular radiotheragnostics directly links nuclear medicine diagnostic imaging to therapy. The imaging study is used to detect a specific molecular target associated with a disease process. A radiotherapeutic molecule with a similar biodistribution to the diagnostic agent can then be used to deliver targeted therapy. Read More

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http://dx.doi.org/10.7861/clinmedicine.17-5-453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301936PMC
October 2017
20 Reads

Recurrent Graves' hyperthyroidism after prolonged radioiodine-induced hypothyroidism.

Ther Adv Endocrinol Metab 2017 Jul 12;8(7):111-115. Epub 2017 Sep 12.

Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 920 Madison Ave, Suite 300A, Memphis TN 38163, USA.

Background: Radioactive iodine (RAI) is the most cost effective therapy for Graves' disease (GD). Patients with GD who have become hypothyroid after therapeutic RAI, rarely develop recurrence of disease. Herein we describe a case of recurrence of thyrotoxicosis after 2 years of hypothyroidism. Read More

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http://dx.doi.org/10.1177/2042018817730278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602214PMC
July 2017
22 Reads

Exogenous T3 toxicosis following consumption of a contaminated weight loss supplement.

Endocrinol Diabetes Metab Case Rep 2017 29;2017. Epub 2017 Aug 29.

Regional Centre for Endocrinology, Royal Victoria Hospital, BelfastUK.

A 42-year-old male presented with a one-week history of palpitations and sweating episodes. The only significant history was of longstanding idiopathic dilated cardiomyopathy. Initial ECG demonstrated a sinus tachycardia. Read More

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http://dx.doi.org/10.1530/EDM-17-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581371PMC
August 2017
9 Reads

Hickam's dictum: Myasthenia Gravis presenting concurrently with Graves' disease.

BMJ Case Rep 2017 Sep 7;2017. Epub 2017 Sep 7.

Department of Endocrinology, Waikato Hospital, Hamilton, New Zealand.

We present two patients with Graves' disease and concurrent myasthenia gravis. The impact of the dual diagnosis on the clinical course and the potential for a delayed diagnosis of myasthenia gravis is discussed. Patient 1, a 28-year-old man was diagnosed with Graves' disease following his second respiratory arrest. Read More

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http://dx.doi.org/10.1136/bcr-2017-220153DOI Listing
September 2017

The Role of Radiopharmaceuticals in Amiodarone-Induced Thyroid Pathology.

Curr Radiopharm 2017 Nov;10(3):146-154

Ion Chiricuta Institute of Oncology, Cluj-Napoca, Romania.

Background And Objective: The use of amiodarone for the treatment of ventricular and supraventricular dysrhythmias brings in organism an increased amount of iodine, interfering with thyroid function. If the treatment needs to be interrupted, iodine remains at abnormal levels for months or even years. The aim of the study was to review the literature regarding the optimal tests for early diagnostic and to analyze the role of nuclear medicine tests in the differential and correct assessment of the amiodarone-induced thyroid pathology. Read More

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http://dx.doi.org/10.2174/1874471010666170816125402DOI Listing
November 2017
13 Reads

Convexity Subarachnoid Hemorrhage Due to Cardioembolic Stroke in a Woman with Thyrotoxicosis: Α Case Report.

J Stroke Cerebrovasc Dis 2017 Oct 2;26(10):e195-e196. Epub 2017 Aug 2.

First Department of Neurology, Eginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Background: Non-traumatic convexity subarachnoid hemorrhage (cSAH) is a rarely reported condition with a wide spectrum of etiologies. Cerebral ischemia secondary to extracranial or intracranial atherosclerotic disease has been identified as a relatively uncommon cause of cSAH.

Case Report: We report a case of cSAH caused by cardioembolic stroke. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.06.045DOI Listing
October 2017
10 Reads

Thyrotoxicosis Presenting as Unilateral Drop Foot.

Intern Med 2017 1;56(15):2053-2056. Epub 2017 Aug 1.

Department of Neurology, Akita Red Cross Hospital, Japan.

Neuromuscular disorders associated with hyperthyroidism have several variations in their clinical phenotype, such as ophthalmopathy, periodic paralysis, and thyrotoxic myopathy. We herein report an unusual case of thyrotoxic myopathy presenting as unilateral drop foot. Histopathological examinations of the left tibialis anterior muscle showed marked variation in the fiber size, mild inflammatory cell infiltration, and necrotic and regenerated muscle fibers with predominantly type 1 fiber atrophy. Read More

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http://dx.doi.org/10.2169/internalmedicine.56.8374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577086PMC
February 2018
1 Read

Serum 25-hydroxyvitamin D might be an independent prognostic factor for Graves disease recurrence.

Medicine (Baltimore) 2017 Aug;96(31):e7700

Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

Graves disease is the most common cause of thyrotoxicosis. Although medical intervention with antithyroid drugs (ATDs) is commonly the first choice of treatment in Korea, the remission rate associated with this approach is not satisfactory. During ATD therapy, low or undetectable serum levels of thyroid-stimulating hormone (TSH) receptor antibodies (TRAbs) have been reported to affect the incidence of Graves disease remission. Read More

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http://dx.doi.org/10.1097/MD.0000000000007700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626158PMC
August 2017
11 Reads

18F-FDG PET/CT imaging of atypical subacute thyroiditis in thyrotoxicosis: A case report.

Medicine (Baltimore) 2017 Jul;96(30):e7535

aPET Imaging Center, Asahi General Hospital bDepartment of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba cDepartment of Diagnostic Radiology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo dDepartment of Radiology, Asahi General Hospital, Chiba, Japan.

Background: In addition to its established role in oncologic imaging, F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) is useful for the assessment of inflammatory activity. However, subacute thyroiditis (SAT) in thyrotoxicosis is rarely detected during these scans.

Case: A 66-year-old man with SAT in thyrotoxicosis demonstrated symptoms of transient fatigue, headache, and fever, without typical neck pain. Read More

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http://dx.doi.org/10.1097/MD.0000000000007535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627825PMC
July 2017
15 Reads

Severe neurological abnormalities in a young boy with impaired thyroid hormone sensitivity due to a novel mutation in the MCT8 gene.

Hormones (Athens) 2017 Apr;16(2):194-199

Pediatric Neurological, Clinical University Hospital of Santiago de Compostela, Santiago, Spain.

Monocarboxylate transporter 8 (MCT8) is an active and specific thyroid hormone transporter into neurons. MCT8 mutations cause an X-linked condition known as Allan-Herndon-Dudley syndrome and are characterized by impaired psychomotor development and typical abnormal thyroid function. We describe a 10-year-old boy with severe cognitive disability, axial hypotonia, spastic quadriplegia and sporadic dyskinetic episodes. Read More

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http://dx.doi.org/10.14310/horm.2002.1733DOI Listing
April 2017
16 Reads

Tricuspid regurgitation and abnormal aortic isthmic flow: prenatal manifestations of hyperthyroidism.

Ultrasound Obstet Gynecol 2017 07;50(1):132-134

Department of Paediatrics, Sainte-Justine University Hospital Center, University of Montreal, 3175 Chemin de la Côte Sainte Catherine, Montreal, Quebec, H3T 1C5, Canada.

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http://dx.doi.org/10.1002/uog.17359DOI Listing

Periodic Paralysis and Encephalopathy as Initial Manifestations of Graves' Disease: Case Report and Review of the Literature.

Neurologist 2017 Jul;22(4):134-137

*Neurology Department, Papageorgiou General Hospital ‡Department of Medicine, Second Medical Clinic, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece †Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Background: Thyrotoxic periodic paralysis (TPP) is an uncommon complication of Graves' disease, characterized by the triad of acute hypokalemia without total body potassium deficit, episodic muscle paralysis, and thyrotoxicosis. Graves' encephalopathy is an extremely rare form of encephalopathy associated with autoimmune thyroid disease (EAATD), characterized by neuropsychiatric symptoms, increased antithyroid antibodies and cerebrospinal fluid protein concentration, nonspecific electroencephalogram abnormalities, and cortico-responsiveness. Coexistence of both these complications in the same patient has not been reported before. Read More

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http://dx.doi.org/10.1097/NRL.0000000000000125DOI Listing
July 2017
10 Reads

Thyrotoxic and pheochromocytoma multisystem crisis: a case report.

J Med Case Rep 2017 Jun 23;11(1):173. Epub 2017 Jun 23.

Department of Emergency and Disaster Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.

Background: Thyrotoxic crisis and pheochromocytoma multisystem crisis are rare, life-threatening, emergency endocrine diseases with various clinical manifestations. Here we report a case of a patient who simultaneously developed thyrotoxic crisis and pheochromocytoma multisystem crisis and required intensive cardiovascular management.

Case Presentation: A 60-year-old Asian man experienced nausea and vomiting, and subsequently developed dyspnea and cold sweats while farming. Read More

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http://dx.doi.org/10.1186/s13256-017-1299-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481964PMC
June 2017
25 Reads

Rapid Improvement of thyroid storm-related hemodynamic collapse by aggressive anti-thyroid therapy including steroid pulse: A case report.

Medicine (Baltimore) 2017 Jun;96(22):e7053

aDepartment of Cardiovascular Medicine bDepartment of Therapeutic Strategy for Heart Failure cDepartment of Endocrinology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Rationale: Heart failure is relatively common in patients with hyperthyroidism, but thyrotoxic cardiomyopathy with poor left ventricular (LV) systolic function is very rare.

Patient Concerns: We experienced a representative case of a patient who presented with severe LV dysfunction related to thyroid storm and needed extracorporeal membrane oxygenation (ECMO) temporally.

Diagnosis: Thyrotoxic cardiomyopathy. Read More

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http://dx.doi.org/10.1097/MD.0000000000007053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459733PMC
June 2017
32 Reads
5.723 Impact Factor

Struma Ovarii With Hyperthyroidism.

Clin Nucl Med 2017 Jun;42(6):475-477

From the *Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, †Nuclear Medicine, Department of Radiology, and ‡Department of Pathology, University of Michigan, Ann Arbor, MI.

We report the case of a 61-year-old woman with persistent thyrotoxicosis for 7 years despite low thyroidal radioiodine uptake and methimazole treatment. Her initial I whole-body scan (WBS) was read as negative. Upon evaluation in our institution, she remained hyperthyroid after discontinuation of methimazole. Read More

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http://dx.doi.org/10.1097/RLU.0000000000001667DOI Listing
June 2017
4 Reads

Acute symptomatic hypocalcemia from immune checkpoint therapy-induced hypoparathyroidism.

Am J Emerg Med 2017 Jul 27;35(7):1039.e5-1039.e7. Epub 2017 Feb 27.

Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

Background: Ipilimumab (a monoclonal antibody against CTLA-4) and nivolumab (a humanized antibody against PD-1) target these immune checkpoint pathways and are used for treatment of melanoma and an increasing number of other cancers. However, they may cause immune-related adverse effects (IRAEs). Although many endocrinopathies are known to be IRAEs, primary hypoparathyroidism with severe hypocalcemia has never been reported. Read More

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http://dx.doi.org/10.1016/j.ajem.2017.02.048DOI Listing
July 2017
6 Reads
1 Citation
1.152 Impact Factor

Unilateral facial swelling in a thyrotoxic patient.

BMJ 2017 Feb 9;356:j534. Epub 2017 Feb 9.

Mater Misericordiae Health Services Brisbane Ltd, Queensland Diabetes and Endocrine Centre, South Brisbane, Queensland, Australia

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http://dx.doi.org/10.1136/bmj.j534DOI Listing
February 2017
3 Reads

Lesson of the month 1: Subacute thyroiditis: a rare cause of fever of unknown origin.

Clin Med (Lond) 2017 Feb;17(1):86-87

Sultan Qaboos University Hospital, Al Khod, Muscat, Oman.

Fever of unknown origin (FUO) is sometimes a diagnostic dilemma for clinicians. Endocrine causes reported in the literature include subacute thyroiditis, thyrotoxicosis, adrenal insufficiency and pheochromocytoma. Among these, subacute thyroiditis is often overlooked as it can occasionally lack typical symptoms. Read More

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http://dx.doi.org/10.7861/clinmedicine.17-1-86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297584PMC
February 2017
14 Reads

Evaluation of Tc-MIBI in thyroid gland imaging for the diagnosis of amiodarone-induced thyrotoxicosis.

Br J Radiol 2017 Mar 20;90(1071):20160836. Epub 2017 Jan 20.

Department of Nuclear Medicine, Tianjin First Central Hospital, Tianjin, China.

Objective: Amiodarone-induced thyrotoxicosis (AIT) is caused by amiodarone as a side effect of cardiovascular disease treatment. Based on the differences in their pathological and physiological mechanisms, many methods have been developed so far to differentiate AIT subtypes such as colour flow Doppler sonography (CFDS) and 24-h radioiodine uptake (RAIU). However, these methods suffer from inadequate accuracy in distinguishing different types of AITs and sometimes lead to misdiagnosis and delayed treatments. Read More

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http://dx.doi.org/10.1259/bjr.20160836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601526PMC
March 2017
6 Reads

Thyrotropin-producing pituitary adenoma simultaneously existing with Graves' disease: a case report.

J Med Case Rep 2017 Jan 6;11(1). Epub 2017 Jan 6.

Department of Neurosurgery, Saiseikai Yokohamashi, Tobu Hospital, Yokohama, Japan.

Background: Thyrotropin-producing pituitary tumor is relatively rare. In particular, concurrent cases associated with Graves' disease are extremely rare and only nine cases have been reported so far. We describe a case of a thyrotropin-producing pituitary adenoma concomitant with Graves' disease, which was successfully treated. Read More

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http://dx.doi.org/10.1186/s13256-016-1172-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217335PMC
January 2017
13 Reads

Infiltrative thyrotoxicosis: an unusual case of diffuse large B cell lymphoma.

Oxf Med Case Reports 2016 Nov 4;2016(11):omw082. Epub 2016 Nov 4.

Consultant Medical Oncologist, University Hospital Limerick , Limerick , Ireland.

Thyrotoxicosis is most commonly caused by Graves' disease, toxic multinodular goitre, a functioning thyroid adenoma, or thyroiditis. Extrinsic infiltrative conditions affecting the thyroid gland are typically destructive, and associated with thyroid hypofunction. We describe the case of a 61-year-old woman who presented to our hospital with symptoms of thyrotoxicosis, neck swelling and thyroid function tests consistent with hyperthyroidism. Read More

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https://academic.oup.com/omcr/article-lookup/doi/10.1093/omc
Publisher Site
http://dx.doi.org/10.1093/omcr/omw082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184839PMC
November 2016
10 Reads

Hyperdynamic Right Heart Function in Graves' Hyperthyroidism Measured by Echocardiography Normalises on Restoration of Euthyroidism.

Heart Lung Circ 2017 Jun 19;26(6):580-585. Epub 2016 Nov 19.

School of Medicine, University of Queensland, Brisbane, Qld, Australia; Nambour General Hospital, Nambour, Qld, Australia.

Background: Graves' hyperthyroidism commonly causes tachycardia and may result in pulmonary hypertension and high output cardiac failure. There is limited information regarding the effect of treatment on cardiac function measured using modern echocardiographic techniques.

Methods: Eight individuals with Graves' hyperthyroidism, aged 22-64 years, underwent comprehensive transthoracic echocardiography at three time points: before treatment, two weeks after commencement of carbimazole, and at six months or more when euthyroid. Read More

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http://dx.doi.org/10.1016/j.hlc.2016.10.007DOI Listing
June 2017
7 Reads

A case of hypercalcaemic crisis secondary to coexistence of primary hyperparathyroidism and Graves' disease.

Endocr Regul 2016 Oct;50(4):225-228

A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation, palpitations and somnolence. Laboratory evaluation revealed a severe hypercalcaemia and overt hyperthyroidism. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Read More

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http://dx.doi.org/10.1515/enr-2016-0024DOI Listing
October 2016
15 Reads

Mild Thyrotoxicosis Leads to Brain Perfusion Changes: An Arterial Spin Labelling Study.

J Neuroendocrinol 2017 01;29(1)

Department of Neurology, University of Lübeck, Lübeck, Germany.

Hypo- and hyperthyroidism have effects on brain structure and function, as well as cognitive processes, including memory. However, little is known about the influence of thyroid hormones on brain perfusion and the relationship of such perfusion changes with cognition. The present study aimed to demonstrate the effect of short-term experimental hyperthyroidism on brain perfusion in healthy volunteers and to assess whether perfusion changes, if present, are related to cognitive performance. Read More

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http://dx.doi.org/10.1111/jne.12446DOI Listing
January 2017
8 Reads