1,456 results match your criteria Thyroiditis Subacute

New aspects in the pathogenesis and management of subacute thyroiditis.

Rev Endocr Metab Disord 2021 May 5. Epub 2021 May 5.

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital, Research Institute, 281/289 Rzgowska St, 93-338, Lodz, Poland.

Subacute thyroiditis (SAT) is a thyroid inflammatory disease, whose pathogenesis and determinants of the clinical course were unclear for many decades. The last few years have brought many clinically significant new data on the epidemiology, pathogenesis and management of SAT. Several human leukocyte antigen (HLA) alleles were demonstrated not only to increase the risk of SAT, but also to correlate with SAT clinical course and determine the risk of recurrence. Read More

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The Association of Subacute Thyroiditis with COVID-19: a Systematic Review.

SN Compr Clin Med 2021 Apr 29:1-13. Epub 2021 Apr 29.

King Edward Medical University, Lahore, 54000 Pakistan.

The multisystem effects of SARS-CoV-2 encompass the thyroid gland as well. Emerging evidence suggests that SARS-CoV-2 can act as a trigger for subacute thyroiditis (SAT). We conducted a systematic literature search using PubMed/Medline and Google Scholar to identify cases of subacute thyroiditis associated with COVID-19 and evaluated patient-level demographics, major clinical features, laboratory findings and outcomes. Read More

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Subacute Thyroiditis and Heart Failure in a Patient Presenting With COVID-19.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211009412

Malcom Randall Veteran Hospital, Gainesville, FL, USA.

A 67-year-old male was admitted with shortness of breath and diarrhea. His COVID-19 polymerase chain reaction test was positive, and he was found to be in acute heart failure. Troponin levels were elevated, echocardiogram showed ejection fraction of 24%, and his electrocardiogram was normal. Read More

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Management of thyroid disorders during the COVID-19 outbreak: a position statement from the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism (SBEM).

Arch Endocrinol Metab 2021 Apr 12. Epub 2021 Apr 12.

Departamento de Tireoide, Sociedade Brasileira de Endocrinologia e Metabologia, Rio de Janeiro, RJ, Brasil.

This position statement was prepared to guide endocrinologists on the best approach to managing thyroid disorders during the coronavirus disease (COVID-19) pandemic. The most frequent thyroid hormonal findings in patients with COVID-19, particularly in individuals with severe disease, are similar to those present in the non-thyroidal illness syndrome and require no intervention. Subacute thyroiditis has also been reported during COVID-19 infection. Read More

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Thyroid sequelae of COVID-19: a systematic review of reviews.

Rev Endocr Metab Disord 2021 06 11;22(2):485-491. Epub 2021 Apr 11.

Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to cause multi-organ effects including endocrine disorders. The impact of COVID-19 on the thyroid gland has been described but several aspects have to be clarified. The systematic review was conceived to achieve more solid information about: 1) which thyroid disease or dysfunction should be expected in COVID-19 patients; 2) whether thyroid patients have a higher risk of SARS-CoV-2 infection; 3) whether the management has to be adapted in thyroid patient when infected. Read More

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Subacute Thyroiditis during the COVID-19 Pandemic: Searching for a Clinical Association with SARS-CoV-2.

Int J Endocrinol 2021 26;2021:5588592. Epub 2021 Mar 26.

Ente Ospedaliero Cantonale, Locarno Regional Hospital, Locarno, Switzerland.

Purpose: To search for a clinical potential link between subacute thyroiditis (SAT) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a series of patients diagnosed with SAT during the COVID-19 pandemic, by retrospective evaluation of (1) clinical symptoms and (2) contact tracing.

Methods: SAT  patients diagnosed from March to December 2020 were enrolled. The presence of typical clinical presentation of SARS-CoV-2, diagnostic tests for SARS-CoV-2, and contact with other individuals proven to be positive for SARS-CoV-2 were searched. Read More

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Primary squamous cell carcinoma of the thyroid: a case report.

J Int Med Res 2021 Apr;49(4):3000605211004702

Department of Endocrinology, Peking University International Hospital, Beijing, China.

Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare and rapidly progressive malignancy that carries a poor prognosis. PSCCT is easily misdiagnosed as acute thyroiditis or as another thyroid malignancy. We have reported a 76-year-old woman who presented with progressive neck pain for 1 month. Read More

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Georgian Med News 2021 Feb(311):98-103

2I.M. Sechenov First Moscow State Medical University (Sechenov University), Russian Federation, Department of Faculty Surgery N2, Russian Federation.

The COVID-19 pandemia has shown that there is not enough knowledge today to fully control it. Along with severe respiratory syndrome, attention has recently been paid to extrapulmonary lesions, including endocrinopathies. The aim of the study was to summarize the current literature data about the effects of the SARS-CoV-2 coronavirus on the thyroid gland. Read More

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February 2021

Antithyroid arthritis syndrome in a case of post-COVID-19 subacute thyroiditis.

Diabetes Metab Syndr 2021 Mar 25;15(3):683-686. Epub 2021 Mar 25.

Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address:

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The utility of liver transplantation to treat acute liver failure caused by adult-onset Still's disease: case reports.

Clin J Gastroenterol 2021 Apr 1. Epub 2021 Apr 1.

Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Purpose: Adult-onset Still's disease (AOSD) is an inflammatory condition commonly complicated by mild liver dysfunction. However, severe liver failure is rarely reported. We report three cases of severe acute hepatic failure (ALF) associated with AOSD. Read More

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A 33-year-old man with COVID-19 presented with subacute thyroiditis: A rare case report and literature review.

New Microbes New Infect 2021 May 22;41:100871. Epub 2021 Mar 22.

Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

We report the first case of the novel coronavirus disease 2019 (COVID-19) presenting with subacute thyroiditis in Ghaemshar, Mazandaran Province, Iran. In our patient, with the initiation of corticosteroid therapy, the symptoms of subacute thyroiditis gradually disappeared with a slow increase in thyroid-stimulating hormone (TSH) and the gradual elimination of thyrotoxicosis. This case shows that decreased TSH and persistent thyrotoxicosis may make the patient's condition worse. Read More

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Thyroiditis and SARS-CoV-2 pandemic: a review.

Philippe Caron

Endocrine 2021 Mar 27. Epub 2021 Mar 27.

Department of Endocrinology and Metabolic diseases, Cardiovascular and Metabolic Unit CHU-Larrey, Toulouse, France.

The world is dealing with the Covid-19 pandemic due to the coronavirus SARS-CoV-2. Amongst the extra-pulmonary manifestations presented by Covid-19 patients, thyroiditis form part of the spectrum of visceral involvement linked to SARS-CoV-2. In this review, we will describe the various documented clinical forms of thyroiditis (inflammatory thyroiditis, subacute or de Quervain's thyroiditis, chronic lymphocytic thyroiditis or Hashimoto's disease, painless (silent) postpartum thyroiditis) to facilitate their diagnosis in more or less symptomatic Covid-19 patients and to provide guidance for patient treatment. Read More

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Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects.

J Endocrinol Invest 2021 Mar 25. Epub 2021 Mar 25.

Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari "Aldo Moro", Bari, Apulia, Italy.

Background: Thyroid dysfunction has been observed in patients with COVID-19, and endocrinologists are requested to understand this clinical issue. Pandemic-related restrictions and reorganization of healthcare services may affect thyroid disease management.

Objective And Methods: To analyze and discuss the relationship between COVID-19 and thyroid diseases from several perspectives. Read More

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Subacute Thyroiditis from COVID-19 Infection: A Case Report and Review of Literature.

Eur Thyroid J 2021 Feb 5;9(6):324-328. Epub 2020 Nov 5.

Division of Infectious Diseases, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, New York, USA.

Introduction: The novel severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) virus has led to the ongoing Coronavirus disease 2019 (COVID-19) disease pandemic. There are increasing reports of extrapulmonary clinical features of COVID-19, either as initial presentations or sequelae of disease. We report a patient diagnosed with subacute thyroiditis precipitated by COVID-19 infection, as well as review the literature of similar cases. Read More

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February 2021

Subacute Thyroiditis in COVID-19 Patients.

Eur Thyroid J 2021 Feb 30;9(6):321-323. Epub 2020 Oct 30.

Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: Since December 2019, novel coronavirus (COVID-19) infection has been identified as the cause of an outbreak of respiratory illness in Wuhan, China. The classic presentation of COVID-19 infection was described as fever, myalgia, cough, and fatigue. Whether coronavirus can directly attack the endocrine glands is unclear. Read More

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February 2021

Anaplastic Thyroid Carcinoma with Initial Ultrasonography Features Mimicking Subacute Thyroiditis.

Endocrinol Metab (Seoul) 2021 Feb 24;36(1):201-202. Epub 2021 Feb 24.

Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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February 2021

COVID-19-related thyroiditis: A novel disease entity?

Clin Endocrinol (Oxf) 2021 Mar 2. Epub 2021 Mar 2.

Centre for Endocrinology, Barts, London School of Medicine, Queen Mary University of London, London, UK.

The literature on COVID-19-related thyroid complications has accumulated over the past year or so as the pandemic has accelerated throughout the world. In particular, several recent case reports have been published describing a possible correlation between COVID-19 disease and subacute thyroiditis (SAT). In this review, we briefly present one of our own patients and review the current published literature in this area up to January 2021, including analyses of major series of thyroid function tests in patients with significant COVID-19 infection. Read More

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The Role of Nuclear Medicine in the Clinical Management of Benign Thyroid Disorders. Part 2. Nodular Goiter, Hypothyroidism, and Subacute Thyroiditis.

J Nucl Med 2021 Feb 12. Epub 2021 Feb 12.

Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, United States.

Goiter, an enlargement of the thyroid gland, is a common endocrine abnormality. Constitutional factors, genetic abnormalities, and/or dietary and environmental factors may contribute to the development of nodular goiter. Most patients with non-toxic nodular goiter are asymptomatic or have only mild mechanical symptoms ("globus pharyngis"). Read More

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February 2021

The cytokine storm and thyroid hormone changes in COVID-19.

J Endocrinol Invest 2021 May 9;44(5):891-904. Epub 2021 Feb 9.

Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.

Background: COVID-19 is now a worldwide pandemic. Among the many extra-pulmonary manifestations of COVID-19, recent evidence suggested a possible occurrence of thyroid dysfunction.

Purpose: The Aim of the present review is to summarize available studies regarding thyroid function alterations in patients with COVID-19 and to overview the possible physio-pathological explanations. Read More

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Suppurative thyroiditis: Systematic review and clinical guidance.

Clin Endocrinol (Oxf) 2021 Feb 9. Epub 2021 Feb 9.

Endocrinology and Diabetes Department, Eastern Health, Melbourne, Vic., Australia.

Objective: Acute suppurative thyroiditis (AST) is a rare but potentially fatal condition which can initially be difficult to distinguish from the more common subacute thyroiditis (SAT). We aim to update understanding of this medical emergency.

Design: A systematic review over the past 20 years was performed on the epidemiology, clinical features, investigations, management and outcomes of AST. Read More

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February 2021

Potential Interaction Between SARS-CoV-2 and Thyroid: A Review.

Endocrinology 2021 03;162(3)

Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

The novel coronavirus disease 2019 (COVID-19) produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sweeping the world in a very short time. Although much has been learned about the clinical course, prognostic inflammatory markers, and disease complications of COVID-19, the potential interaction between SARS-CoV-2 and the thyroid is poorly understood. In contrast to SARS-CoV-1, limited available evidence indicates there is no pathological evidence of thyroid injury caused by SARS-CoV-2. Read More

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A Case of Post-COVID-19 Subacute Thyroiditis.

Cureus 2020 Dec 26;12(12):e12301. Epub 2020 Dec 26.

Internal Medicine, Faisalabad Medical University, Faisalabad, PAK.

Subacute thyroiditis is usually a self-limiting inflammatory condition. The clinical presentation varies from person to person, but usually includes neck pain or discomfort and a painful diffuse goiter. There is at times a transient episode of hyperthyroidism followed by euthyroidism and sometimes hypothyroidism. Read More

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December 2020

Endocrine Involvement in COVID-19: Mechanisms, Clinical Features, and Implications for Care.

Indian J Endocrinol Metab 2020 Sep-Oct;24(5):381-386. Epub 2020 Nov 9.

Director and Chief Executive Officer, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Coronavirus 2019 (COVID -19) has rapidly emerged as a global pandemic with multi-system involvement. Involvement of the endocrine system is expected in COVID-19 as the interplay between severe acute respiratory syndrome corona virus-2 (SARS CoV-2) and the endocrine system occurs at multiple levels. The widespread presence of ACE-2 receptors on various tissues suggests scope for direct viral infection. Read More

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November 2020

Thyroid complications of SARS and coronavirus disease 2019 (COVID-19).

Endocr J 2021 Feb 19;68(2):129-136. Epub 2021 Jan 19.

Department of Orthopaedics, Municipal Clinic Biatorbágy, H-2051, Biatorbágy, Hungary.

We have reviewed the available literature on thyroid diseases and coronavirus disease 2019 (COVID-19), and data from the previous coronavirus pandemic, the severe acute respiratory syndrome (SARS) epidemic. We learned that both SARS and COVID-19 patients had thyroid abnormalities. In the limited number of SARS cases, where it was examined, decreased serum T3, T4 and TSH levels were detected. Read More

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February 2021

The Importance of Vitamin D Level in Subacute Thyroiditis Disease and the Effect of Vitamin D on Disease Prognosis.

Endocr Pract 2020 Oct;26(10):1062-1069

Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Objective: Subacute thyroiditis (SAT) is an inflammatory thyroid disease that manifests with severe pain. The presence of the vitamin D receptor in immune system cells shows that vitamin D deficiency can trigger inflammatory diseases. The aim of the present study was to determine the prevalence of vitamin D deficiency in SAT patients, and the relationship between vitamin D level and permanent hypothyroidism and recurrence rate. Read More

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October 2020

Platelet-Lymphocyte Ratio as a Novel Surrogate Marker to Differentiate Thyrotoxic Patients with Graves Disease from Subacute Thyroiditis: a Cross-Sectional Study from South India.

Endocr Pract 2020 Sep;26(9):939-944

Department of Endocrinology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India.

Objective: Graves disease (GD) and the toxic phase of subacute thyroiditis (SAT) have similar clinical and biochemical presentations, and differentiating them requires sophisticated investigations. Since thyroid hormones have been noted to affect all hematologic cell lines, we have used the platelet lymphocyte ratio (PLR)-an index usually utilized in inflammatory or malignant disorders-to compare patients with and without thyrotoxicosis and to analyze its use in distinguishing between patients with GD and SAT prior to therapy.

Methods: This was a cross-sectional study conducted in the Department of Endocrinology, Christian Medical College, Vellore, India. Read More

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September 2020

Short-Term Versus 6-Week Prednisone In The Treatment Of Subacute Thyroiditis: A Randomized Controlled Trial.

Endocr Pract 2020 Aug;26(8):900-908

the Department of Endocrinology, The Second Affiliated Hospital of Third Military Medical University, Chongqing, China.

Objective: Moderate-to-severe subacute thyroiditis is clinically managed with 6 to 8 weeks of glucocorticoid therapy. However, no studies have evaluated short-term prednisone treatment for subacute thyroiditis.

Methods: This 24-week, prospective, single-blind, randomized controlled study enrolled patients (aged 18 to 70 years) with subacute thyroiditis who were hospitalized between August, 2013, and December, 2014. Read More

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Evaluation of interleukin-29 in autoimmune and inflammatory thyroid diseases.

Clin Endocrinol (Oxf) 2021 Jan 15. Epub 2021 Jan 15.

Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.

Objective: Interleukins play an important role in the development of autoimmune disorders. The aim of this study was to compare the concentration of interleukin-29 (IL-29) between healthy controls (CS) and patients with selected thyroid disorders: Graves' disease (GD), Hashimoto's thyroiditis (HT) and subacute thyroiditis (SAT).

Design And Methods: The following parameters were examined in the group of 95 individuals (45 with GD, 22 with HT, 28 with SAT) and 72 CS: thyroid hormones and autoantibodies, inflammatory markers and the concentration of IL-29 in serum. Read More

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January 2021

Subacute thyroiditis presenting with creeping in a 6-year-old boy.

Clin Pediatr Endocrinol 2021 5;30(1):75-78. Epub 2021 Jan 5.

Department of Pediatrics, Tanegashima Medical Center, Nishinoomote-city, Japan.

Among the types of acute thyroiditis, subacute thyroiditis (SAT) is rare in children, and there is limited knowledge regarding its characteristics in pediatric cases. We present a case of SAT in a 6-yr-old boy who was brought to our hospital with high fever and pain in the front portion of the neck. Acute suppurative thyroiditis (AST), which is common in children, was suspected initially. Read More

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January 2021

Deep learning for intelligent diagnosis in thyroid scintigraphy.

J Int Med Res 2021 Jan;49(1):300060520982842

Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Objective: To construct deep learning (DL) models to improve the accuracy and efficiency of thyroid disease diagnosis by thyroid scintigraphy.

Methods: We constructed DL models with AlexNet, VGGNet, and ResNet. The models were trained separately with transfer learning. Read More

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January 2021