490 results match your criteria Thyroid Substernal Goiter

Morbidity Associated With Surgical Removal of Substernal Thyroid Goiters.

J Surg Res 2022 Apr 30;277:254-260. Epub 2022 Apr 30.

Division of Endocrine Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.

Introduction: Surgical excision of substernal thyroid goiters (STG) can be challenging while minimizing postoperative morbidity. Postoperative complication rates associated with transcervical and transthoracic approaches (i.e. Read More

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Navigating the Debate on Managing Large (≥4 cm) Thyroid Nodules.

Int J Endocrinol 2022 16;2022:6246150. Epub 2022 Apr 16.

University of Vermont Medical Center, Burlington, VT, USA.

Purpose: Discordant practice guidelines for managing large thyroid nodules may result in unnecessary surgeries and costs. Recent data suggest similar false-negative rates in fine needle aspiration (FNA) biopsies between small (<4 cm) and large (≥4 cm) nodules, indicating that monitoring rather than surgery may be appropriate for large biopsy-negative nodules. We investigated the management of thyroid nodules ≥4 cm to determine the proportion of surgeries not necessary for diagnostic purposes and examined for potential predictors. Read More

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Minimally invasive combined approach robotic thymectomy and transcervical total thyroidectomy.

BMJ Case Rep 2022 Apr 22;15(4). Epub 2022 Apr 22.

Cardiothoracic Surgery, Cooper University Health Care, Camden, New Jersey, USA.

Myasthenia gravis (MG) is the most common autoimmune disorder affecting the neuromuscular junction in the USA. It is not uncommon for these patients to have concomitant autoimmune diseases including autoimmune thyroid disease. We describe here our method of performing a reproducible robotically assisted one-stage thymectomy and thyroidectomy. Read More

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Evaluation of multinodular goiter and primary hyperparathyroidism leads to a diagnosis of AL amyloidosis.

Thyroid Res 2022 Apr 20;15(1). Epub 2022 Apr 20.

Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, USA.

Background: Amyloid goiter, defined as excess amyloid within the thyroid gland in such quantities that it produces a clinically apparent goiter, is a very rare manifestation of systemic amyloidosis with cases commonly seen in the setting of Amyloid A (AA) amyloidosis. Amyloid goiter as the primary clinical manifestation secondary to Amyloid light chain (AL) amyloidosis is very rare. We present a case of AL amyloidosis with initial manifestation as goiter with amyloid deposition in the thyroid and the parathyroid gland. Read More

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Large non-functioning substernal parathyroid cyst: A case report and review of the literature.

Int J Surg Case Rep 2022 Apr 29;93:106989. Epub 2022 Mar 29.

Department of Surgery, Section of Otolaryngology, University of Chicago Medicine, Chicago, IL, USA. Electronic address:

Objectives: Parathyroid cysts are rare benign lesions of the head and neck that account for less than 1% of cystic neck masses. We present a rare case of a large 6 cm substernal parathyroid cyst.

Presentation Of Case: An otherwise healthy 65 year-old female presented to the otolaryngology clinic for evaluation of an anterior, midline neck mass. Read More

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Retrosternal Goitre: Anatomical Aspects and Technical Notes.

Medicina (Kaunas) 2022 Feb 25;58(3). Epub 2022 Feb 25.

Endocrine Surgery Unit, Department of Surgery, Veneto Institute of Oncology, IOV-IRCCS, Via Gattamelata 64, 35128 Padua, Italy.

surgery for substernal goitre is still debated in the literature, due to the wide range of surgical options. This article outlines the findings of our extensive experiences, which include 264 cases of patients with "goitre plongeant", and compares postoperative complications, despite surgical approaches. : preoperative planning and anatomical landmarks are described to determine the potential need of a combined approach. Read More

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February 2022

Intrathoracic Goiter Visualized on iodine-123 and technetium-99m Single-Photon Emission Computed Tomography/Computed Tomography.

World J Nucl Med 2021 Oct-Dec;20(4):377-378. Epub 2021 Nov 1.

Department of Internal Medicine, Clinic for Endocrinology and Diabetes, Viborg Regional Hospital, Viborg, Denmark.

Goiter with an intrathoracic component is relatively common; however, it is less common to see extent outside the anterior or posterior mediastinum. We present a case of intrathoracic goiter of significant size and abnormal placement which is examined using both Tc-pertechnetate and iodine-123 single-photon emission computed tomography/computed tomography. Read More

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November 2021

Laryngeal varices: an atypical cause of globus.

BMJ Case Rep 2021 Dec 30;14(12). Epub 2021 Dec 30.

Otolaryngology, Portsmouth Hospitals University NHS Trust, Portsmouth, UK

Laryngeal varices are rare and are usually associated with vocal cord trauma secondary to excessive use of voice. This report is the first documented case of laryngeal varices secondary to thyroid goitre. This is a report of an 83-year-old woman with a known retrosternal goitre chiefly with symptoms of globus. Read More

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December 2021

[Retrosternal goiter in thoracic surgical practice].

Khirurgiia (Mosk) 2021 (12):20-26

Harefield Hospital of the Royal Brompton and Harefield Hospital NHS Foundation Trust, Harefield, UK.

Objective: To evaluate and optimize surgical approaches to the management of retrosternal goiter.

Material And Methods: A cohort retrospective single-center study included 56 patients aged 68.3±9. Read More

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December 2021

Substernal goitre presenting with upper and lower extremity oedema.

BMJ Case Rep 2021 Nov 1;14(11). Epub 2021 Nov 1.

Department of Otolaryngology/HNS, LSUHSC-S, Shreveport, Louisiana, USA.

Substernal goitre is characterised by compressive symptoms of the airway and oesophagus. Chronic, progressive symptoms usually result in surgical removal. We report a rare presentation of substernal goitre in a male in his early 70s who suffered from severe bilateral lower extremity (LE) lymphoedema, resulting in immobility and nursing home placement, and left upper extremity lymphoedema. Read More

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November 2021

Preoperative Evaluation of Substernal Goiter by Computed Tomography in the Extended Neck Position.

Case Rep Oncol 2021 Sep-Dec;14(3):1353-1358. Epub 2021 Sep 20.

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.

Sternotomy is indicated when a goiter cannot be resected via a cervical incision, such as in the case of a substernal goiter extending beyond the aortic arch. In this article, we report a case of a large substernal goiter that was successfully removed using the cervical approach only. This is a case of a 68-year-old woman, diagnosed with goiter 20 years ago, who complained of a neck mass enlargement with associated cough. Read More

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September 2021

Risk Factors and Outcomes of Postoperative Neck Hematomas: An Analysis of 5,900 Thyroidectomies Performed at a Cancer Center.

Int Arch Otorhinolaryngol 2021 Jul 30;25(3):e421-e427. Epub 2020 Sep 30.

AC Camargo Cancer Center, São Paulo, SP, Brazil.

 Postoperative neck hematoma (PNH) is an uncommon but potentially-lethal complication of thyroid surgery.  To identify the risk factors for postthyroidectomy hematoma requiring reoperation, the timing, the source of the bleeding, the related respiratory distress requiring tracheotomy, and the late outcomes.  We retrospectively analyzed the records of 5,900 consecutive patients submitted to surgery for thyroid diseases at a single institution. Read More

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Sutureless Thyroidectomy With Intraoperative Neuromonitoring and Energy-Based Device Without Sternotomy for Symptomatic Substernal Goiter Harboring Thyroiditis of Gland Parenchyma.

Cureus 2021 Jul 8;13(7):e16258. Epub 2021 Jul 8.

General Surgery, Giresun University Faculty of Medicine, Giresun, TUR.

Since substernal goiter first being described by Haller in 1749, a consensus on the definition of this entity has not been ensured, yet. Despite substernal goiter or retrosternal goiter is delineated as an enlarged thyroid gland with a component extending into the mediastinum, at least 10 definitions have described being able to depict the most accurate definition for substernal goiter. Of note, no consensus still has been declared on the therapeutic management of asymptomatic substernal goiter. Read More

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Estimation of Chest Wall Attenuation of I Emissions in Substernal Goiter: A Phantom Study.

J Nucl Med Technol 2021 Sep 9;49(3):232-234. Epub 2021 Jul 9.

Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

In patients with substernal goiter, the generally accepted theory is that thyroid uptake measurements with iodine isotopes are underestimated because of attenuation by the chest wall. The extent of this underestimation is not well known. In this study, we calculated the attenuation of I emissions using a cadaver chest wall with a thyroid probe to better understand the potential severity of this underestimation. Read More

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September 2021

Efficacy and safety of single-session radiofrequency ablation for intrathoracic goiter: preliminary results and short-term evaluation.

Int J Hyperthermia 2021 ;38(1):976-984

Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: An intrathoracic goiter (ITG) is defined as a thyroid extension below the sternal notch. Compared to cervical goiters, surgery for ITG is more challenging, with a higher risk of an extracervical approach. Ultrasound (US)-guided radiofrequency ablation (RFA) is a minimally invasive treatment modality. Read More

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Airway Management in Substernal Goiter Surgery.

Ann Otol Rhinol Laryngol 2021 May 25:34894211014794. Epub 2021 May 25.

Department of Otolaryngology-Head & Neck Surgery, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.

Objective(s): To review the experience of 3 hospitals with airway management during surgery for substernal goiter and identify preoperative factors that predict the need for advanced airway management techniques.

Methods: A retrospective chart review between 2009 and 2017 of patients with substernal goiter treated surgically at 1 of 3 hospitals was performed.

Results: Of the 179 patients included in the study, 114 (63. Read More

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Anatomical and developmental aspects of iatrogenic injury to the right recurrent laryngeal nerve in surgical resections of substernal goiter.

Anat Rec (Hoboken) 2021 06 9;304(6):1242-1254. Epub 2021 Apr 9.

Hospital Universitario Gaffree e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.

Thyroid surgery is the primary treatment for substernal goiters, and iatrogenic injury to the recurrent laryngeal nerve (RNL) is always a risk. The literature suggests that iatrogenic lesions of the RNL post resection of substernal goiter are not equally distributed, being more frequent on the right recurrent laryngeal nerve (R-RLN) in comparison to the left recurrent laryngeal nerve (L-RLN). The relative paucity of basic anatomical and clinical reportages on R-RLN iatrogenic injuries and on the developmental factors that may help explain its higher incidence justifies this study's undertaking. Read More

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Combined cervicosternotomy and cervicotomy for true retrosternal goiters: a surgical cohort study.

Updates Surg 2021 Aug 29;73(4):1-10. Epub 2021 Mar 29.

Department of Head and Skin, University Hospital Ghent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.

Objective: Intrathoracic goiters are a heterogeneous group characterized by limited or extensive substernal extension. Whereas the former can be treated through cervicotomy, the latter sometimes requires a cervicosternotomy. Whether cervicosternotomy leads to more morbidity remains unclear. Read More

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Cervical approach to cervico-mediastinal goiters: Experience of a Moroccan ENT tertiary center - Case series.

Ann Med Surg (Lond) 2021 Feb 26;62:353-357. Epub 2021 Jan 26.

ENT Head and Neck Surgery Department, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Background: The purpose of the study was to analyze and discuss the demographic, clinical, radiological, therapeutic and postoperative findings of the Cervico-mediastinal goiters (CMG) treated through a cervical approach admitted in the ENT department of Ibn Rochd university hospital, Casablanca, Morocco between January 2014 and January 2020.

Materiels And Methods: Over a period of 6 years, 116 patients underwent surgical treatment for CMG. It was defined as a goiter extending below the plane of superior thoracic aperture on CT scan. Read More

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February 2021

Sutureless Total Thyroidectomy for Substernal Goiter: Amending Versus Unnecessary.

Cureus 2021 Jan 15;13(1):e12720. Epub 2021 Jan 15.

Pathology, Giresun University Faculty of Medicine, Giresun, TUR.

Substernal goiter is an enlarged thyroid gland, harboring a component extending into the mediastinum. Surgical management requires genuine and rigorous preoperative planning as physicians could encounter the prospect of the gland coming into close quarters with the vital intrathoracic structures. The neck and chest multiplanar cross-sectional imaging provide essentialness of an extracervical approach for the procedure. Read More

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January 2021

Retrosternal goiter.

Rozhl Chir 2020 ;99(11):492-496

Introduction: Retrosternal goiter is an enlarged thyroid mass of which more than 50% is located in the mediastinum. Indications for surgery of retrosternal goiter include ineffective pharmacological treatment, mechanical syndrome, suspicion of malignancy and thyrotoxicosis. Computed tomography is the gold standard in the diagnosis of retrosternal goiter. Read More

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January 2021

A Cohort Study Assessing the Association Between Body Composition Parameters and Symptomatic Hypocalcemia After Total Thyroidectomy.

Am Surg 2021 Aug 19;87(8):1305-1312. Epub 2020 Dec 19.

Department of General Surgery, 63990Ankara University School of Medicine, Turkey.

Background: Postoperative hypocalcemia is one of the major concerns following thyroidectomy and the most frequent cause of prolonged hospital stay. The aim of this study was to evaluate the relationship between body composition parameters and symptomatic hypocalcemia following total thyroidectomy. In addition, the effects of disease- and patient-related factors on hypocalcemia were investigated. Read More

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fT3:fT4 ratio in Graves' disease - correlation with TRAb level, goiter size and age of onset.

Folia Med Cracov 2020 09;60(2):15-27

Department of Endocrinology Jagiellonian University Medical College.

Introduction: Graves' Disease (GD) is an autoimmune hyperthyroidism occurring mostly in young women. The main pathogenic role of the disease is attributed to TSH receptor antibodies (TRAb), which stimulate the thyroid gland to increase production of the most active thyroid hormone- triiodothyronine (T3). High level of TRAb and a large goiter size are commonly known as poor prognostic factors for the disease and are used to predict relapse. Read More

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September 2020

An overview of retrosternal goiter.

M Knobel

J Endocrinol Invest 2021 Apr 11;44(4):679-691. Epub 2020 Aug 11.

Thyroid Unit, Division of Endocrinology and Metabolism, Hospital das Clínicas, School of Medicine, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 155, 8th floor, bl 3, PAMb, São Paulo, 05403-900, Brazil.

Goiters tend to grow slowly and steadily over many years, occasionally reaching the mediastinum and extending through the thoracic inlet into the visceral compartment. In most cases, retrosternal goiters originate from the cervical portion of the thyroid. The incidence of retrosternal goiters varies considerably, ranging from 0. Read More

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Peculiar anatomic variation of recurrent laryngeal nerve and EMG change in a patient with right substernal goiter and pre-operative vocal cord palsy-case report.

Gland Surg 2020 Jun;9(3):802-805

School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.

We report a patient with right substernal goiter and preoperative vocal cord palsy (VCP). During dissection, an anatomic variation of the recurrent laryngeal nerve (RLN) and a prolonged EMG were detected by intraoperative neuromonitoring (IONM). Symmetrical vocal cord movement was recorded one month after surgery. Read More

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Substernal Goiter: a case to remember.

Rev Assoc Med Bras (1992) 2020 May;66(2):109-111

. Department of Internal Medicine. Hospital Trofa Saúde Vila Real. Vila Real, Portugal.

Goiter is a localized or generalized thyroid hypertrophy. It can remain within the cervical region or grow down until it invades the mediastinum. The signs and symptoms depend on the size and location of the goiter. Read More

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Surgery for retrosternal goiter: cervical approach.

Gland Surg 2020 Apr;9(2):392-400

Department of Head and Neck Surgery, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China.

Background: Retrosternal goiter refers to when the thyroid gland extends from the neck to the substernal portion, descending below the thoracic inlet into the mediastinum. It is typically accompanied by compressive symptoms, and most patients need to undergo surgery. This retrospective study set out to analyze the surgical approach to retrosternal goiter and to evaluate perioperative complications, with the aim of recommending best surgical technique. Read More

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