4,356 results match your criteria Thyroid Nodule Imaging


Georgian Med News 2021 Apr(313):79-84

1Tyumen State Medical University; Russia.

To search for effective and safe methods aimed at reducing the frequency of surgical treatment for nodular thyroid pathology. 1999-2019 literature review conducted using NLM databases. There is more and more evidence in the literature on the efficacy and safety of minimally invasive treatments for thyroid nodular disease. Read More

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Well-Differentiated Thyroid Cancer Invading the Trachea in a Pediatric Patient.

AACE Clin Case Rep 2021 May-Jun;7(3):207-210. Epub 2021 Mar 23.

University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, Michigan.

Objectives: Pediatric thyroid cancer is rare. Most cases are well-differentiated thyroid cancers (WDTCs). However, gross laryngotracheal invasion of WDTCs is unusual. Read More

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A Preliminary Study of Quantitative Ultrasound for Cancer-Risk Assessment of Thyroid Nodules.

Front Endocrinol (Lausanne) 2021 19;12:627698. Epub 2021 May 19.

Section of Endocrinology, Diabetes and Nutrition, Boston Medical Center, Boston University School of Medicine, Boston, MA, United States.

Background: Gray-scale, B-mode ultrasound (US) imaging is part of the standard clinical procedure for evaluating thyroid nodules (TNs). It is limited by its instrument- and operator-dependence and inter-observer variability. In addition, the accepted high-risk B-mode US TN features are more specific for detecting classic papillary thyroid cancer rather than the follicular variant of papillary thyroid cancer or follicular thyroid cancer. Read More

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American Association of Clinical Endocrinology And Associazione Medici Endocrinologi Thyroid Nodule Algorithmic Tool.

Endocr Pract 2021 Jun 2. Epub 2021 Jun 2.

Mayo Clinic College of Medicine, Rochester, Minnesota.

Objective: The first edition of the American Association of Clinical Endocrinology/American College of Endocrinology/Associazione Medici Endocrinologi Guidelines for the Diagnosis and Management of Thyroid Nodules was published in 2006 and updated in 2010 and 2016. The American Association of Clinical Endocrinology/American College of Endocrinology/Associazione Medici Endocrinologi multidisciplinary thyroid nodules task force was charged with developing a novel interactive electronic algorithmic tool to evaluate thyroid nodules.

Methods: The Thyroid Nodule App (termed TNAPP) was based on the updated 2016 clinical practice guideline recommendations while incorporating recent scientific evidence and avoiding unnecessary diagnostic procedures and surgical overtreatment. Read More

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Ultrasound Image Classification of Thyroid Nodules Using Machine Learning Techniques.

Medicina (Kaunas) 2021 May 24;57(6). Epub 2021 May 24.

School of Medicine, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland.

: Thyroid nodules are lumps of solid or liquid-filled tumors that form inside the thyroid gland, which can be malignant or benign. Our aim was to test whether the described features of the Thyroid Imaging Reporting and Data System (TI-RADS) could improve radiologists' decision making when integrated into a computer system. In this study, we developed a computer-aided diagnosis system integrated into multiple-instance learning (MIL) that would focus on benign-malignant classification. Read More

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Incidental Thyroid Nodules on Imaging: Relevance and Management.

Radiol Clin North Am 2021 Jul;59(4):525-533

Department of Radiology, University of Alabama at Birmingham, 619 19th Street South, GSB 409, Birmingham, AL 35249, USA.

Incidental thyroid nodules (ITNs) are commonly detected on imaging examinations performed for other reasons, particularly computed tomography (CT) (and now PET-CT and even PET-MR imaging), MR imaging, and sonography, primarily a consequence of the increasing sensitivity of these diagnostic modalities. Appropriate management of ITNs is crucial to avoid the cost and medical consequences of unnecessary workups. Read More

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Symptomatic aseptic necrosis of benign thyroid lesions after microwave ablation: risk factors and clinical significance.

Int J Hyperthermia 2021 ;38(1):815-822

Department of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, China.

Background: Symptomatic aseptic necrosis (SAN) followed by nodule rupture is a kind of severe complications after thermal ablation for benign thyroid nodules (BTN). No studies are available to evaluate its pathologic process, clinical manifestations, risk factors and effectiveness of therapies after microwave ablation (MWA).

Methods: From 2012 to 2019, 398 patients who received MWA for BTN were retrospectively reviewed. Read More

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January 2021

Role of elastography strain ratio and TIRADS score in predicting malignant thyroid nodule.

Arch Endocrinol Metab 2021 May;64(6):735-742

Kasr Al-Aini Hospitals, Cairo University, Cairo, Egypt,

Objective: Ultrasonography (US) is the most accurate and cost-effective imaging method in diagnosis of thyroid nodules. A practical thyroid imaging reporting and data system (TIRADS) for thyroid nodules has been proposed to classify nodules of the thyroid gland to solve the problem of nodule selection for fine needle aspiration cytology (FNAC). Real-time elastography and strain ratio (SR) is a method used to assess the stiffness and predict the malignancy of thyroid nodules. Read More

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Papillary thyroid microcarcinoma: is active surveillance always enough?

Clin Endocrinol (Oxf) 2021 May 21. Epub 2021 May 21.

Department of Endocrinology and Diabetes, Royal North Shore Hospital Sydney, Australia.

The incidence of papillary thyroid carcinoma (PTC) has increased over recent decades. This apparent epidemic has been attributed to the overdiagnosis of small PTC ≤ 10mm in diameter (PTMC) incidentally detected on imaging for unrelated presentations. While most PTMC follow an indolent disease course, there is a small but significant proportion of cases that display more biologically aggressive features such as early metastasis and lymph node involvement. Read More

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Primary hyperparathyroidism presenting as a brown tumor with hypercalcemia crisis in a second-trimester pregnant woman: A case report.

Yun Xu Yingying Yu

Medicine (Baltimore) 2021 May;100(20):e25968

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.

Introduction: Primary hyperparathyroidism (PHPT) in pregnancy is rare and unrecognized because the maternal physiological adaptations blurs the symptoms. There is no standard treatment strategy for maternal PHPT. Early diagnosis and interventions can prevent catastrophic consequences to the mother and fetus. Read More

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Thyroid "claw sign" a useful diagnostic marker in the outsized lesions of isthmus: A large colloid cyst.

Radiol Case Rep 2021 Jul 30;16(7):1688-1694. Epub 2021 Apr 30.

Department of Orthopedics, Jarir Medical Centre, Riyadh, Saudi Arabia.

Thyroid isthmus lesions are generally small sized and can be solid or cystic. Discerning isthmic origin of a large nodule, especially if purely cystic, can become a diagnostic challenge because of thin thyroid tissue in it. We report a case of a 68-year-old male patient who had 6 weeks history of non- inflammatory central neck swelling associated with recent dysphagia, for which he underwent ultrasound and computed tomography (CT) scan examinations. Read More

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Painful Subacute Thyroiditis is Commonly Misdiagnosed as Suspicious Thyroid Nodular Disease.

Mayo Clin Proc Innov Qual Outcomes 2021 Apr 3;5(2):330-337. Epub 2021 Feb 3.

Thyroid Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Objective: To investigate and characterize the clinical and radiologic features of 10 patients with painful subacute thyroiditis with ultrasound findings considered suspicious for malignancy or for whom biopsy of a suspicious area was recommended by an attending radiologist.

Patients And Methods: Ten patients with painful subacute thyroiditis were seen from June 1, 2016, through January 1, 2019. All 10 patients presented to an endocrine or thyroid clinic with a neck ultrasound report stating findings suspicious for malignancy or nodular disease. Read More

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Risk Stratification in Patients With Follicular Neoplasm on Cytology: Use of Quantitative Characteristics and Sonographic Patterns.

Front Endocrinol (Lausanne) 2021 30;12:614630. Epub 2021 Apr 30.

Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.

Objectives: Differentiating thyroid nodules with a cytological diagnosis of follicular neoplasm remains an issue. The goal of this study was to determine whether ultrasonographic (US) findings obtained preoperatively from the computer-aided detection (CAD) system are sufficient to further stratify the risk of malignancy for this diagnostic cytological category.

Methods: From September 2016 to September 2018 in our hospital, patients diagnosed with Bethesda category IV (follicular neoplasm or suspicion of follicular neoplasm) thyroid nodules and underwent surgical excisions were include in the study. Read More

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Comparison of British Thyroid Association, American College of Radiology TIRADS and Artificial Intelligence TIRADS with histological correlation: diagnostic performance for predicting thyroid malignancy and unnecessary fine needle aspiration rate.

Br J Radiol 2021 Jun 9:20201444. Epub 2021 Jun 9.

Department of Radiology, Glasgow Royal Infirmary, NHS GG&C, Glasgow, UK.

Objectives: To compare diagnostic performance of British Thyroid Association (BTA), American College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS) and Artificial Intelligence TIRADS (AI-TIRADS) for thyroid nodule malignancy. To determine comparative unnecessary fine needle aspiration (FNA) rates.

Methods: 218 thyroid nodules with definitive histology obtained during 2017 were included. Read More

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Non-functioning oxyphilic parathyroid carcinoma: a case report.

Surg Case Rep 2021 May 12;7(1):119. Epub 2021 May 12.

Department of Pathology, Showa University Northern Yokohama Hospital, 35-1 Chigasakichuo, Tsuzuki-ku, Yokohama-shi, Kanagawa, Tokyo, 224-8503, Japan.

Background: Non-functioning parathyroid carcinoma is an extremely rare malignancy among endocrine tumors. We report a case in which non-functional oxyphilic parathyroid carcinoma was diagnosed from clinical symptoms and pathological diagnosis.

Case Presentation: The patient was a 42-year-old man with no medical or family history of note. Read More

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[Cervical Abscess after Surgery for Subglottic Granuloma due to Suture Thread Used at Thyroplasty with Arytenoid Adduction].

Kyobu Geka 2021 Feb;74(2):116-119

Department of Thoracic Surgery, Eiju General Hospital, Tokyo, Japan.

A 83-year-old man underwent thyroplasty with arytenoid adduction for right recurrent laryngeal nerve palsy 1 year ago. He had been suffering from hemosputum and cough for last 2 months, and was referred to our hospital for medical examination. Laryngoscopy and neck computed tomography showed subglottic nodule. Read More

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February 2021

Testing telediagnostic thyroid ultrasound in Peru: a new horizon in expanding access to imaging in rural and underserved areas.

J Endocrinol Invest 2021 May 10. Epub 2021 May 10.

Pontifica Universidad Catolica del Peru, Av. Universitaria 1801, 15088, San Miguel, Peru.

Purpose: Thyroid ultrasound is a key tool in the evaluation of the thyroid, but billions of people around the world lack access to ultrasound imaging. In this study, we tested an asynchronous telediagnostic ultrasound system operated by individuals without prior ultrasound training which may be used to effectively evaluate the thyroid and improve access to imaging worldwide.

Methods: The telediagnostic system in this study utilizes volume sweep imaging (VSI), an imaging technique in which the operator scans the target region with simple sweeps of the ultrasound probe based on external body landmarks. Read More

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Effects of Implementing a Higher Threshold for Recommending Thyroid Biopsies on Malignancy Rates.

Perm J 2021 May;25

Hawaii Permanente Medical Group, Honolulu, HI.

Introduction: We implemented a new thyroid nodule classification system in which a biopsy was recommended for thyroid lesions ≥ 1 cm with at least 2 or more suspicious features.

Methods: Three consecutive years of thyroid biopsies using the new classification system were reviewed for patient demographics, biopsy recommendation based on nodule size and imaging characteristics, and pathology results. The primary outcome was malignancy rates for thyroid biopsies. Read More

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Differences in the ultrasonographic appearance of thyroid nodules after radiofrequency ablation.

Clin Endocrinol (Oxf) 2021 May 3. Epub 2021 May 3.

Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.

Context: Radiofrequency ablation (RFA) is a well-tolerated approach to treating benign thyroid nodules (TNs), but no index can predict its success. Other than size decrease, little is known about TN appearance on ultrasonography (US) after RFA.

Objective: This study aimed to (a) assess the effectiveness of single-session RFA treatment, (b) determine whether pre-ablation US characteristics correlate with its effectiveness, and (c) demonstrate TN characteristics on baseline and follow-up US. Read More

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Thyroid hemiagenesis with a TI-RADS 2 nodule in the contralateral lobe.

Thyroid Res 2021 Apr 30;14(1):10. Epub 2021 Apr 30.

Department of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

Background: Thyroid hemiagenesis is a rare congenital anomaly in which one lobe of the thyroid gland fails to develop. There is an increased incidence of associated thyroid disorders in patients with thyroid hemiagenesis.

Case Presentation: A 32-year-old Ugandan woman presented with a complaint of painless neck swelling of 3-months duration. Read More

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Thyroid nodules in childhood-onset Hashimoto's thyroiditis: Frequency, risk factors, follow-up course and genetic alterations of thyroid cancer.

Clin Endocrinol (Oxf) 2021 Apr 24. Epub 2021 Apr 24.

Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Children's Hospital, Seoul, Korea.

Objective: We evaluated the frequency, risk factors and the follow-up outcomes of thyroid nodules, and genetic alterations in thyroid cancer, in youth with childhood-onset Hashimoto thyroiditis (HT) residing in an iodine-sufficient country.

Design: A retrospective cohort study.

Patients And Measurements: A total of 213 patients (194 females, mean age 10. Read More

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Ultrasound criteria (EU-TIRADS) to identify thyroid nodule malignancy risk in adolescents. Correlation with cyto-histological findings.

Endocrinol Diabetes Nutr (Engl Ed) 2021 Apr 19. Epub 2021 Apr 19.

Sección Endocrinología Pediátrica, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, CIBER de Enfermedades Raras (CIBERER) ISCIII, EndoERN, Barcelona, España.

Introduction: Thyroid nodule (TN) harboring a thyroid carcinoma are more common in pediatric than adult patients. In pediatric population, the evaluation of a TN should require specific pediatric tools for its diagnostic and therapeutic management. High-resolution ultrasonography and cytological evaluation after fine-needle aspiration biopsy (FNAB) remain the cornerstones of evaluation of TN. Read More

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Solitary thyroid metastasis from colorectal cancer: Case report.

Hwansoo Kim

Int J Surg Case Rep 2021 Apr 22;81:105804. Epub 2021 Mar 22.

Department of Surgery, Kangwon National University Hospital, Kangwon National University Hospital, 156, Baengnyeong-ro, Chuncheon-Si, Gangwon-Do 24289, Republic of Korea. Electronic address:

Introduction And Importance: Thyroid metastasis of colorectal cancer is rare and the patient with thyroid metastasis has no symptoms early in the disease course. On the other hand, evaluation of thyroid is not generally included in the routine follow-up of colorectal cancer. Therefore, the diagnosis of thyroid metastasis of colorectal cancer may be delayed. Read More

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Multimodal ultrasound imaging of primary thyroid schwannoma: A case report.

Medicine (Baltimore) 2021 Apr;100(16):e25517

Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, China.

Rationale: Primary schwannoma of the thyroid gland is very rare, and its preoperative diagnosis is difficult.

Patient Concerns: We report the case of a thyroid nodule in an 18-year-old woman, who presented with a mass in her left neck with stiffness and normal thyroid function. However, the patient complained of numbness in her left upper extremity, and ultrasound (US) features were suspicious of malignancy. Read More

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A Collision Intrathyroidal Tumor Causing Primary Hyperparathyroidism: Evidence From an 18F-Choline PET/CT Study.

Clin Nucl Med 2021 Apr 15. Epub 2021 Apr 15.

From the Departments of Internal Medicine Pathology, Galliera Hospital Departments of Pathology Endocrine Surgery, San Martino Hospital Department of Nuclear Medicine, Galliera Hospital, Genoa, Italy.

Abstract: A 67-year-old man was diagnosed with primary hyperparathyroidism and normofunctioning left nodular goiter. Fine-needle aspiration cytology showed thyroid (Thy) 4 (suspicious of malignancy). After first-line imaging proved negative, integrated 18F-choline PET/4D contrast-enhanced CT revealed uptake by the thyroid nodule and by 3 nodules of the left central compartment. Read More

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Ultrasonic Characteristics of Medullary Thyroid Carcinoma: Differential From Papillary Thyroid Carcinoma and Benign Thyroid Nodule.

Ultrasound Q 2021 Apr 10. Epub 2021 Apr 10.

Ultrasound Department, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Abstract: The aim of this study was to evaluate the differences in ultrasonic features of patients with medullary thyroid carcinoma (MTC), papillary thyroid carcinoma (PTC), and benign thyroid nodules. This study included 53 cases of MTC, 151 cases of PTC, and 200 cases of benign thyroid nodule which were pathologically confirmed. There were no significant differences in sex and thyroid gland involvement among the MTC, PTC, and benign thyroid nodule groups. Read More

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Ultrasound features of medullary thyroid cancer as predictors of biological behavior.

Cancer Imaging 2021 Apr 9;21(1):33. Epub 2021 Apr 9.

Departments of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, P. R. China.

Background: Medullary thyroid cancer (MTC) has more aggressive behavior and poor prognosis. Ultrasound (US) has facilitated the qualitative diagnosis of thyroid nodules, however, some MTC may be diagnosed as a benign nodule on ultrasound because ultrasound features of malignancy are lacking. The aim of the study was to investigate the association between ultrasound features and biological behavior of MTC. Read More

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Primary squamous cell carcinoma of the thyroid: a case report.

J Int Med Res 2021 Apr;49(4):3000605211004702

Department of Endocrinology, Peking University International Hospital, Beijing, China.

Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare and rapidly progressive malignancy that carries a poor prognosis. PSCCT is easily misdiagnosed as acute thyroiditis or as another thyroid malignancy. We have reported a 76-year-old woman who presented with progressive neck pain for 1 month. Read More

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An efficient deep convolutional neural network model for visual localization and automatic diagnosis of thyroid nodules on ultrasound images.

Quant Imaging Med Surg 2021 Apr;11(4):1368-1380

Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.

Background: The aim of this study was to construct a deep convolutional neural network (CNN) model for localization and diagnosis of thyroid nodules on ultrasound and evaluate its diagnostic performance.

Methods: We developed and trained a deep CNN model called the Brief Efficient Thyroid Network (BETNET) using 16,401 ultrasound images. According to the parameters of the model, we developed a computer-aided diagnosis (CAD) system to localize and differentiate thyroid nodules. Read More

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