3,603 results match your criteria Thyroid Nodule Imaging


A Variance-Reduction Approach to Detection of Thyroid Nodule Boundary on Ultrasound Images.

Ultrason Imaging 2019 Apr 16:161734619839648. Epub 2019 Apr 16.

1 Institute of Industrial Engineering, National Taiwan University, Taipei.

To perform computer-aided diagnosis of the thyroid nodules on ultrasound images, the location and boundary of nodules should be clearly defined. However, the identification of thyroid nodule boundary is a difficult issue due to the biological characteristics of the nodules, the physics and quality of ultrasound imaging, and the subjective factors and operating conditions of the operator. In this study, we propose a novel and semiautomatic method for detecting the boundary of thyroid nodule based on the Variance-Reduction (V-R) statistics without image preprocessing. Read More

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http://dx.doi.org/10.1177/0161734619839648DOI Listing

Sclerosing pneumocytoma: Case report of a rare endobronchial presentation.

Medicine (Baltimore) 2019 Apr;98(15):e15038

Diagnostic Radiology, Imaging Institute.

Rationale: Sclerosing pneumocytoma is a rare benign lung neoplasm seen in middle aged adults with a female predominance. Originally thought to be vascular in origin, this rare entity is now understood to be epithelial in nature. On imaging, sclerosing pneumocytoma manifests as a well circumscribed nodule or mass, often juxtapleural in location. Read More

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http://dx.doi.org/10.1097/MD.0000000000015038DOI Listing
April 2019
1 Read

[Application of nuclear magnetic dispersion weighted imaging and apparent diffusion coefficient in the identification of benign].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Apr;33(4):342-346

Department of Head and Neck Surgery, Shanxi Province Tumor Hospital,Taiyuan,030013,China.

To determine the diagnostic role of diffusionweighted imaging(DWI) and apparent diffusion coefficient(ADC) under different b values in differentiating benign and malignant thyroid nodules by using postoperative histopathological results were taken as the reference standard. From January 2017 to June 2018, 64 patients with thyroid nodules diagnosed by ultrasound in the head and neck surgery of Shanxi Cancer Hospital were collected, and a total of 80 nodules were collected. The Philips 3. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.04.013DOI Listing
April 2019
1 Read

A review of the propriety of thyroid ultrasound referrals and their follow-up burden.

Endocrine 2019 Apr 6. Epub 2019 Apr 6.

Department of Endocrinology, Connolly Hospital, Blanchardstown, Co Dublin, Ireland.

Purpose: The overdiagnosis of thyroid nodules and indolent thyroid cancers represents an increasing burden on health services, with thyroid ultrasound (US) imaging often representing the initial entry point into the thyroid nodule diagnostic pathway. The aim of this study was to retrospectively review thyroid US referrals to a single Irish hospital to determine if the stated indications for imaging had been appropriate, to review the results of the scans, and to assess the follow-up required in each case.

Methods: Patient demographics, scan indications, results, and outcomes were retrospectively reviewed for all patients undergoing thyroid ultrasound from 2012 to 2016. Read More

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http://dx.doi.org/10.1007/s12020-019-01920-1DOI Listing
April 2019
3 Reads

Value of differential diagnosis of contrast-enhanced ultrasound in benign and malignant thyroid nodules with microcalcification.

Oncol Lett 2019 May 4;17(5):4545-4549. Epub 2019 Mar 4.

Department of Ultrasound, People's Hospital of Shanxi Province, Taiyuan, Shanxi 030012, P.R. China.

Value of differential diagnosis of contrast-enhanced ultrasound in benign and malignant thyroid nodules with microcalcification was explored. A total of 184 patients with thyroid nodules with microcalcification, treated in People's Hospital of Shanxi Province from April 2015 to March 2017, were selected as research subjects. Contrast-enhanced ultrasound was used for imaging examination of the thyroid nodules. Read More

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http://dx.doi.org/10.3892/ol.2019.10107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444473PMC

Doughnut Shaped Parathyroid Adenoma

Mol Imaging Radionucl Ther 2019 Mar;28(1):41-43

University of Health Sciences, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Pathology, Ankara, Turkey

A 52-year-old woman presented with a complaint of neck swelling. The patient showed signs of hyperparathyroidism: hypercalcemia, and hypophosphatemia. Tc-99m MIBI dual-phase parathyroid scintigraphy and SPECT revealed increased activity in a regular-bordered, “doughnut”-shaped mass on the left side of the thyroid gland with a central hypoactive area. Read More

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http://dx.doi.org/10.4274/mirt.galenos.2018.06977DOI Listing
March 2019
7 Reads

False-positive I-131 Uptakes at Pulmonary Wedge-resection Site and Soft Tissue Lateral to the Femoral Heads in a Patient with Papillary Thyroid Carcinoma

Mol Imaging Radionucl Ther 2019 Mar;28(1):34-37

Ege University Faculty of Medicine, Department of Nuclear Medicine, İzmir, Turkey

A hyper-metabolic pulmonary nodule was detected on 18F-FDG PET/CT in a 65-year-old woman who had been followed up for 12 years without any complaints following treatment for papillary thyroid cancer (PTC). Wedge resection was performed to the pulmonary nodule and the pathologic examination revealed PTC metastasis. On the post-therapeutic I-131 scan after radioiodine treatment, focal I-131 uptake was detected at the site of pulmonary wedge resection. Read More

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http://cms.galenos.com.tr/Uploads/Article_25973/MIRT-28-34-E
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http://dx.doi.org/10.4274/mirt.galenos.2018.09821DOI Listing
March 2019
4 Reads

Machine Learning-Assisted System for Thyroid Nodule Diagnosis.

Thyroid 2019 Mar 30. Epub 2019 Mar 30.

Guangzhou, Guangdong, China ;

Background: Ultrasound (US) examination is helpful in differential diagnosis of thyroid nodules (malignant vs. benign), but its accuracy relies heavily on examiner experience. Therefore, we aimed to develop a less subjective diagnostic model aided by machine learning. Read More

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http://dx.doi.org/10.1089/thy.2018.0380DOI Listing
March 2019
2 Reads

Sonography of the Thyroid.

Authors:
Jill E Langer

Radiol Clin North Am 2019 May 7;57(3):469-483. Epub 2019 Feb 7.

The Perelman School of Medicine at the University of Pennsylvania, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address:

Nodular thyroid disease is very common, and the vast majority of nodules are benign. Sonography serves as an effective diagnostic tool in identifying nodular features that are concerning for malignancy and those with a benign appearance. The American College of Radiology has developed a risk-stratification system called the Thyroid Imaging Reporting and Data System, which uses the sonographic appearance of nodules combined with nodule size to determine the need for fine-needle aspiration or sonographic surveillance to diagnose malignancy. Read More

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http://dx.doi.org/10.1016/j.rcl.2019.01.001DOI Listing
May 2019
1 Read

High-intensity focused ultrasound (HIFU) for benign thyroid nodules: 2-year follow-up results.

Endocrine 2019 Mar 28. Epub 2019 Mar 28.

Department of Nuclear Medicine and Thyroid Centre, Imaging Institute of Southern Switzerland, Bellinzona, 6500, Switzerland.

Background: High-intensity focused ultrasound (HIFU) is the last introduced thermal treatment of thyroid nodules. Here we evaluated the results at 24 months after HIFU.

Methods: Since 2016, HIFU was considered as a therapeutic option at our institute in patients with benign thyroid nodules presenting local symptoms. Read More

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http://link.springer.com/10.1007/s12020-019-01909-w
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http://dx.doi.org/10.1007/s12020-019-01909-wDOI Listing
March 2019
2 Reads

Similarities and Differences Between Thyroid Imaging Reporting and Data Systems.

AJR Am J Roentgenol 2019 Mar 27:1-9. Epub 2019 Mar 27.

1 Department of Radiology, GangNeung Asan Hospital, Gangneung-si Gangwon-do, 25440, Korea.

Objective: The purposes of this study were to identify the similarities and differences among the Korean Thyroid Imaging Reporting and Data System (TIRADS), American College of Radiology (ACR) TI-RADS, and European TIRADS and to compare the diagnostic performance of sonographic fine-needle aspiration (FNA) criteria for detecting malignant thyroid nodules.

Materials And Methods: This study included 2274 consecutively evaluated thyroid nodules 1 cm or larger in 1836 patients with final diagnoses from January 2011 to December 2016. US features of the nodules were retrospectively reviewed and classified according to three published guidelines from international societies. Read More

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http://dx.doi.org/10.2214/AJR.18.20510DOI Listing
March 2019
1 Read

Integration of Sonoelastography Into the TIRADS Lexicon Could Influence the Classification.

Front Endocrinol (Lausanne) 2019 11;10:127. Epub 2019 Mar 11.

Department of Oncological Endocrinology and Nuclear Medicine, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.

Numerous TIRADS (Thyroid Image Reporting and Data System) classifications have been developed, and various ultrasound (US) parameters are employed in different countries. The aim of our study was to introduce risk classification and management in a native population based on the Guidelines of Polish National Societies Diagnostics and Treatment of Thyroid Carcinoma but with the addition of sonoelastography. We examined prospectively 208 patients with 305 thyroid lesions employing B-mode ultrasound and sonoelastography (SE). Read More

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http://dx.doi.org/10.3389/fendo.2019.00127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421271PMC
March 2019
1 Read

Minimally-invasive treatments for benign thyroid nodules: a Delphi-based consensus statement from the Italian minimally-invasive treatments of the thyroid (MITT) group.

Int J Hyperthermia 2019 26;36(1):376-382. Epub 2019 Mar 26.

aa Division of Interventional Radiology , IEO, European Institute of Oncology IRCCS , Milan , Italy.

Benign thyroid nodules are a common clinical occurrence and usually do not require treatment unless symptomatic. During the last years, ultrasound-guided minimally invasive treatments (MIT) gained an increasing role in the management of nodules causing local symptoms. In February 2018, the Italian MIT Thyroid Group was founded to create a permanent cooperation between Italian and international physicians dedicated to clinical research and assistance on MIT for thyroid nodules. Read More

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http://dx.doi.org/10.1080/02656736.2019.1575482DOI Listing
March 2019
1 Read

PET/CT in thyroid nodule and differentiated thyroid cancer patients. The evidence-based state of the art.

Rev Endocr Metab Disord 2019 Mar 21. Epub 2019 Mar 21.

Clinic of Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Lugano, Bellinzona, Switzerland.

A more conservative approach to the clinical management of thyroid nodules and differentiated thyroid cancer has recently been proposed by the 2015 ATA guidelines. In this context, fine-needle aspiration biopsy has been reserved for nodules with particular ultrasound features or dimensions that exclude low-risk thyroid lesions. Accordingly, a less aggressive surgical approach (i. Read More

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http://link.springer.com/10.1007/s11154-019-09491-2
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http://dx.doi.org/10.1007/s11154-019-09491-2DOI Listing
March 2019
6 Reads

Non-invasive follicular thyroid neoplasm with papillary-like nuclearfeatures (NIFTP): a review and update.

Endocrine 2019 Mar 13. Epub 2019 Mar 13.

Division of Cytopathology, Department of Pathology, The Johns-Hopkins Hospital, Baltimore, USA.

Background: The nomenclature "Non-invasive Follicular Neoplasm with Papillary-like Nuclear Features (NIFTP)" was introduced in 2016. While NIFTP differs from classic papillary thyroid carcinoma (PTC) in imaging, cytomorphology, histology, molecular profile, treatment, follow up, outcome, and behavior, it largely overlaps with follicular variant of PTC at imaging and cytomorphology. Herein, we review the literature for better understanding NIFTP, and its impact on patient care. Read More

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http://dx.doi.org/10.1007/s12020-019-01887-zDOI Listing
March 2019
2 Reads

Impact of thyroid nodule sizes on the diagnostic performance of Korean thyroid imaging reporting and data system and contrast-enhanced ultrasound.

Clin Hemorheol Microcirc 2019 Mar 7. Epub 2019 Mar 7.

Department of Ultrasound, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi, China.

Objective: This study aimed to evaluate the impact of thyroid nodule sizes on the diagnostic performance of Korean thyroid imaging reporting and data system (TIRADS) and contrast-enhanced ultrasound (CEUS).

Methods: In total, 308 consecutive patients with 382 thyroid nodules underwent US-guided FNA or surgery were included in this retrospective study. The nodule size was classified into 3 categories: ≤10 mm (group A), 10-20 mm (group B), and ≥20 mm (group C). Read More

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http://dx.doi.org/10.3233/CH-180545DOI Listing
March 2019
3 Reads

Virtual Touch Tissue Imaging and Quantification (VTIQ) combined with the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) for malignancy risk stratification of thyroid nodules.

Clin Hemorheol Microcirc 2019 Mar 2. Epub 2019 Mar 2.

In-Patient Ultrasound Department, Second Affiliated Hospital of Harbin Medical University, Nangang, Harbin, Heilongjiang prov, China.

Objective: This study was conducted to investigate the diagnostic performance of Virtual Touch Tissue Imaging and Quantification (VTIQ), combined with the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) in differentiating malignant and benign thyroid nodules.

Methods: A total of 130 thyroid nodules in 128 patients were included. The diagnostic performance of conventional ultrasound (US), VTIQ, and the combination of these two techniques was calculated and compared according to the area under the receiver operating characteristic curve (AUROC), for sensitivity, specificity, and accuracy. Read More

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/CH-180477DOI Listing
March 2019
10 Reads

Diagnostic value of high b-value (2000 s/mm2) DWI for thyroid micronodules.

Medicine (Baltimore) 2019 Mar;98(10):e14298

Scientific Marketing, Siemens Healthcare Ltd., Zhonghuannan Road, Beijing, China.

The aim of the study was to assess the diagnostic value of high b-value (2000 s/mm) diffusion-weighted imaging (DWI) in differentiating malignant from benign thyroid micronodules.Consecutive patients with thyroid micronodules scheduled for Ultrasound (US)-guided fine-needle aspiration biopsy (FNAB) or surgery were underwent high b-value DWI with 3 b-values: 0, 800, and 2000 s/mm. Signal intensity ratios (SIRs) of thyroid micronodules to adjacent normal thyroid tissue on DWI were measured as SIRb0, SIRb800 and SIRb2000. Read More

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http://dx.doi.org/10.1097/MD.0000000000014298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417555PMC
March 2019
1 Read

Multispectral optoacoustic tomography of benign and malignant thyroid disorders - a pilot study.

J Nucl Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Nuclear Medicine, University Hospital Münster, Germany, Germany.

This study aims at evaluating hybrid multispectral optoacoustic tomography (MSOT)/ultrasound for imaging of thyroid disorders, including Graves' disease and thyroid nodules. The functional biomarkers and tissue parameters deoxygenated (HbR), oxygenated (HbO2) and total hemoglobin (HbT), saturation of hemoglobin (sO2), fat and water content were analyzed in thyroid lobes affected by Graves' disease ( = 6), thyroid lobes with healthy thyroid tissue ( = 8), benign ( = 13) and malignant ( = 3) thyroid nodules. In Graves' disease, significantly higher values for HbR (3. Read More

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http://dx.doi.org/10.2967/jnumed.118.222174DOI Listing
March 2019
1 Read

Multiple endocrine neoplasia type 2A syndrome (MEN2A) and usefulness of 68Ga-DOTATATE PET/CT in this syndrome.

Ann Ital Chir 2019 Mar 4;8. Epub 2019 Mar 4.

Aim: The aim of this study was to evaluate a new imaging method 68Ga-DOTATATE PET/CT as an alternative method to diagnose evidence of neuroendocrine tumors or their metastasis (if any) in patient with MEN 2A.

Methods: Three patients( 2F, 1M; age 28,46 and 50 years) with MEN 2A syndrome who underwent 68Ga-DOTATATE PET/CT scan were prospectively evaluated. PET/CT images were analyzed with measurement of maximum standardized uptake value (SUVmax). Read More

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March 2019
5 Reads
0.683 Impact Factor

Ectopic Parathyroid Adenoma in Piriform Sinus: Case Report and Review of the Literature.

Ear Nose Throat J 2019 Jan 28;98(1):14-17. Epub 2019 Jan 28.

1 Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.

During routine blood work, a 53-year-old female patient was noted to have asymptomatic hypercalcemia and subsequently found to have hyperparathyroidism. Localization studies for a suspected parathyroid adenoma included Tc Sestamibi scintigraphy, Single Photon Emission Computed Tomography (SPECT)/computed tomography (CT) study, and ultrasound of the neck, which were initially read as negative for parathyroid adenoma. A contrast-enhanced CT scan of the neck was performed to locate the suspected parathyroid adenoma and demonstrated a soft tissue lesion within the right piriform sinus. Read More

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http://dx.doi.org/10.1177/0145561318822933DOI Listing
January 2019
2 Reads

Comparison and preliminary discussion of the reasons for the differences in diagnostic performance and unnecessary FNA biopsies between the ACR TIRADS and 2015 ATA guidelines.

Endocrine 2019 Mar 4. Epub 2019 Mar 4.

Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, 130000, Jilin, China.

Objectives: (1) To compare the American College of Radiology (ACR) thyroid imaging reporting and data system (TIRADS) and American Thyroid Association (ATA) guidelines for thyroid nodules with regard to diagnostic performance and effectiveness at reducing the number of fine-needle aspiration (FNA) biopsies and to preliminarily discuss the reasons for the differences and (2) to compare the diagnostic performance of the two guidelines in the subgroup of nodules <1 cm in diameter.

Materials And Methods: In the present study, 1000 thyroid nodules in 894 consecutive patients with final diagnoses were included; these thyroid nodules were investigated via FNA biopsies in our hospital. The ultrasound (US) features of the thyroid nodules were reviewed and stratified according to the categories defined by the ACR TIRADS and ATA guidelines. Read More

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http://dx.doi.org/10.1007/s12020-019-01886-0DOI Listing
March 2019
1 Read

Diagnostic value of multimodal ultrasound imaging in differentiating benign and malignant TI-RADS category 4 nodules.

Int J Clin Oncol 2019 Mar 1. Epub 2019 Mar 1.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.

Background: Differential diagnosis of benign and malignant thyroid imaging reporting and data system category 4 (TI-RADS-4) nodules can be difficult using conventional ultrasound (US). This study aimed to evaluate whether multimodal ultrasound imaging can improve differentiation and characterization of benign and malignant TI-RADS-4 nodules.

Methods: Multimodal ultrasound imaging, including US, superb microvascular imaging (SMI), and real-time elastography (RTE), were performed on 196 TI-RADS-4 nodules (78, benign; 118, malignant) in 170 consecutive patients. Read More

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http://dx.doi.org/10.1007/s10147-019-01397-yDOI Listing
March 2019
4 Reads

A case report of a giant mature teratoma of the thyroid gland in a young girl.

Medicine (Baltimore) 2019 Mar;98(9):e14703

Rationale: Teratomas are extremely rare in the thyroid gland. A cervical teratoma presenting as a cystic or mixed thyroid lesion can be easily confused with a thyroglossal duct cyst. It is difficult for pediatricians to differentiate between these 2 types of lesions. Read More

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http://dx.doi.org/10.1097/MD.0000000000014703DOI Listing
March 2019
1 Read

Validation of web-based thyroid imaging reporting and data system in atypia or follicular lesion of undetermined significance thyroid nodules.

Head Neck 2019 Feb 24. Epub 2019 Feb 24.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

Background: Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) show variable malignancy risk. We validated the web-based predictive models and the scoring system by the American College of Radiology (ACR) for AUS/FLUS nodules to stratify the malignancy risk.

Methods: From January 2011 to November 2014, 275 consecutive nodules diagnosed as AUS/FLUS were enrolled. Read More

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http://dx.doi.org/10.1002/hed.25677DOI Listing
February 2019
2 Reads

Accuracy of the European Thyroid Imaging Reporting and Data System (EU-TIRADS) in the valuation of thyroid nodule malignancy in reference to the post-surgery histological results.

Pol J Radiol 2018 19;83:e579-e586. Epub 2018 Dec 19.

Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Poland.

Purpose: To assess the clinical usefulness of the European Thyroid Imaging and Reporting Data System (EU-TIRADS) in the valuation of thyroid nodules malignancy in reference to post-surgery histological results.

Material And Methods: Pre-operative ultrasound was performed in consecutive patients admitted for thyroid surgery between June 2017 and January 2018. Thyroid nodules were classified according to EU-TIRADS to five groups: 1-5. Read More

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http://dx.doi.org/10.5114/pjr.2018.81556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384399PMC
December 2018
1 Read

Ectopic thyroid-stimulating hormone-secreting pituitary adenoma of the nasopharynx diagnosed by Ga-DOTA-TATE PET/CT.

World Neurosurg 2019 Feb 21. Epub 2019 Feb 21.

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of California, San Francisco.

Ectopic thyroid-secreting hormone (TSH)-secreting pituitary adenomas are rare, with only nine cases reported in the literature. We describe a case of an ectopic TSH-secreting pituitary adenoma located in the nasopharynx in a patient initially presenting with signs and symptoms of hyperthyroidism that persisted despite treatment with anti-thyroid medications. Magnetic resonance imaging (MRI) of the pituitary gland was normal, though subsequent review by neuroradiology revealed a nodule attached to the posterior septum in the nasopharynx that was, in retrospect, seen on several other MR scans. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.022DOI Listing
February 2019
2 Reads

Two sequential applications of high-intensity focused ultrasound (HIFU) ablation for large benign thyroid nodules.

Eur Radiol 2019 Feb 18. Epub 2019 Feb 18.

Department of Radiology, The University of Hong Kong, Hong Kong SAR, China.

Objective: High-intensity focused ultrasound (HIFU) ablation is a promising treatment for benign thyroid nodules but single application is less effective in larger-sized nodules. We aimed to assess the efficacy and safety of two sequential applications in larger-sized nodules.

Methods: Fifty patients underwent ablation of a large-sized nodule (baseline volume ≥ 20 mL and diameter ≤ 50 mm). Read More

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http://dx.doi.org/10.1007/s00330-019-06021-1DOI Listing
February 2019
1 Read

Should we perform fine needle aspiration cytology of subcentimetre thyroid nodules? A retrospective review of local practice.

Ultrasound 2019 Feb 9;27(1):64-68. Epub 2019 Jan 9.

Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore, Singapore.

In light of the rising rate of incidentally detected subcentimetre thyroid nodules due to improved surveillance and diagnostic imaging, the decision of whether to perform fine needle aspiration cytology is increasingly pertinent. We aim to assess (1) the sampling adequacy of fine needle aspiration cytology, (2) malignancy rate, (3) thyroidectomy rate and (4) diagnostic accuracy of fine needle aspiration cytology. A total of 245 subcentimetre nodules in 220 patients underwent fine needle aspiration cytology between 2011 and 2014. Read More

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http://dx.doi.org/10.1177/1742271X18820556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362542PMC
February 2019
2 Reads

Systematic thyroid screening in myotonic dystrophy: link between thyroid volume and insulin resistance.

Orphanet J Rare Dis 2019 02 13;14(1):42. Epub 2019 Feb 13.

CHU Lille, Endocrinology, Diabetology and Metabolism, F-59000, Lille, France.

Background: Myotonic dystrophy (DM1), a neuromuscular disease related to DMPK gene mutations, is associated to endocrine disorders and cancer. A routine endocrine work-up, including thyroid ultrasound (US), was conducted in 115 genetically-proven DM1 patients in a neuromuscular reference center. The aim of this study was to determine the prevalence and the causes of US thyroid abnormalities in DM1. Read More

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http://dx.doi.org/10.1186/s13023-019-1019-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375124PMC
February 2019
3 Reads

False negative rate of fine-needle aspiration in thyroid nodules: impact of nodule size and ultrasound pattern.

Head Neck 2019 Apr 10;41(4):967-973. Epub 2019 Feb 10.

Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.

Background: To retrospectively evaluate the false negative rate of ultrasound-guided fine needle aspiration (FNA) according to the nodule size and ultrasound pattern.

Methods: We included 432 consecutive thyroid nodules from 384 patients who underwent ultrasound-guided FNA with benign results (≥1 cm). The false negative rate in the nodules was assessed according to the nodule size and ultrasound pattern based on the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS). Read More

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http://dx.doi.org/10.1002/hed.25530DOI Listing
April 2019
1 Read

Risk Threshold Algorithm for Thyroid Nodule Management Demonstrates Increased Specificity and Diagnostic Accuracy as Compared With American College of Radiology Thyroid Imaging, Reporting and Data System; Society of Radiologists in Ultrasound; and American Thyroid Association Management Guidelines.

Ultrasound Q 2019 Feb 4. Epub 2019 Feb 4.

University of Colorado Denver, Aurora, CO.

We studied diagnostic performance of an algorithm guiding thyroid nodule management using a malignancy risk model as compared with extant management guidelines. Single-institution, retrospective study was performed with sequential cases from pathology registry from 2012 to 2015. Seventy-eight patients were enrolled, with benign and malignant groups defined by aspiration results. Read More

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http://Insights.ovid.com/crossref?an=00013644-900000000-9970
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http://dx.doi.org/10.1097/RUQ.0000000000000420DOI Listing
February 2019
13 Reads

A DIRECT COMPARISON OF THE ATA AND TI-RADS ULTRASOUND SCORING SYSTEMS.

Endocr Pract 2019 Jan 18. Epub 2019 Jan 18.

Department of Surgery, University of California at San Francisco-UCSF, San Francisco, CA.

Abtract Background: This study compares the American Thyroid Association (ATA) classification system with the 2017 Thyroid Imaging Reporting and Data System (TI-RADS) for predicting cancer risk in thyroid nodules.

Methods: This is a retrospective review of ultrasound imaging of all adult patients with thyroid nodules >5mm who underwent thyroidectomy at a tertiary care hospital in 2016. We assessed the ability of either system to predict malignancy based on surgical histopathology. Read More

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http://journals.aace.com/doi/10.4158/EP-2018-0369
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http://dx.doi.org/10.4158/EP-2018-0369DOI Listing
January 2019
8 Reads

Non-invasive Small Vessel Imaging of Human Thyroid Using Motion-Corrected Spatiotemporal Clutter Filtering.

Ultrasound Med Biol 2019 Apr 2;45(4):1010-1018. Epub 2019 Feb 2.

Department of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA. Electronic address:

Reliable assessment of small vessel blood flow in the thyroid, without using any contrast agents, can be challenging because of increased physiological motion resulting from its proximity to the pulsating carotid artery. In this study, we hypothesized that correction of tissue motion prior to singular value decomposition (SVD)-based clutter filtering can improve the coherency of the tissue components and, thus, may allow better clutter suppression and visualization of small vessels in the thyroid. We corroborated this hypothesis by conducting phantom and in vivo studies using a clinical ultrasound scanner implemented with compounded plane wave imaging. Read More

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http://dx.doi.org/10.1016/j.ultrasmedbio.2018.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391182PMC
April 2019
10 Reads

Clinical Diagnostic Evaluation of Thyroid Nodules.

Endocrinol Metab Clin North Am 2019 03;48(1):61-84

Division of Endocrinology and Metabolism, The Ohio State University Wexner Medical Center, 1581 Dodd Drive, 5th Floor McCampbell Hall, South, Columbus, OH 43210, USA. Electronic address:

The presence of a thyroid nodule may be recognized by the patient or the clinician on palpation of the neck or it may be an incidental finding during an imaging study for some other indication. The method of detection is less important, however, than distinguishing benign lesions from more aggressive neoplasms. This article outlines the diagnostic algorithm for the evaluation of thyroid nodules including biochemical testing, imaging, and, when appropriate, fine-needle aspiration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898529183058
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http://dx.doi.org/10.1016/j.ecl.2018.11.001DOI Listing
March 2019
14 Reads

Deep convolutional neural network for the diagnosis of thyroid nodules on ultrasound.

Head Neck 2019 Apr 4;41(4):885-891. Epub 2019 Feb 4.

Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.

Background: We designed a deep convolutional neural network (CNN) to diagnose thyroid malignancy on ultrasound (US) and compared the diagnostic performance of CNN with that of experienced radiologists.

Methods: Between May 2012 and February 2015, 589 thyroid nodules in 519 patients were diagnosed as benign or malignant by surgical excision. Experienced radiologists retrospectively reviewed the US of the thyroid nodules in a test set. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.25415
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http://dx.doi.org/10.1002/hed.25415DOI Listing
April 2019
12 Reads
2.641 Impact Factor

[Interpreted American College of Radiology TI-RADS classification system of ultrasonography for thyroid nodules in 2017 edition and the experiences in clinical application].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Jan;54(1):73-77

Department of Ultrasound, Guangdong General Hospital (Guangdong Academy of Medical Sciences) , Guangzhou 510080, China.

Thyroid nodules are extremely common. Ultrasonography is the most effective imaging modality to diagnose and differentiate thyroid nodules. There are many versions of thyroid image reporting and data system(TI-RADS) evaluated by ultrasound, but some classification system indexes are complicated and clinical application is chaotic. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2019.01.018DOI Listing
January 2019

Diagnostic pitfalls in a cystic ectopic intrathyroidal parathyroid adenoma mimicking a nodular goiter: A care-compliant case report.

Medicine (Baltimore) 2019 Feb;98(5):e14351

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Rationale: Cystic parathyroid adenomas are rare and seldom arise in ectopically located glands which may be found within the carotid sheath, mediastinum, thymus, or thyroid grand. They cannot be detected consistently by any imaging methods. Unusual symptoms may bring about certain pitfalls and difficulties for the diagnosis of primary hyperparathyroidism (PHPT) caused by cystic parathyroid adenomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000014351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380700PMC
February 2019
4 Reads

Retrospective Application of the 2015 American Thyroid Association Guidelines for Ultrasound Classification, Biopsy Indications, and Follow-up Imaging of Thyroid Nodules: Can Improved Reporting Decrease Testing?

Can Assoc Radiol J 2019 Feb;70(1):68-73

Division of Endocrinology, Department of Medicine, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada.

Introduction: Thyroid ultrasound has been widely used to determine which nodules need further investigation. The goal of this study is to determine if using an ultrasonographic features checklist based on 2015 American Thyroid Association (ATA) guidelines can improve reporting and decrease unnecessary further testing.

Methods: In this retrospective study, ultrasonographic images of all nodules biopsied at our institution in 2014 and 2015 were reviewed by radiologists blinded to fine needle aspiration (FNA) biopsy result using a checklist. Read More

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http://dx.doi.org/10.1016/j.carj.2018.09.001DOI Listing
February 2019
1 Read

Follow-up of Benign Thyroid Nodules-Can We Do Less?

Can Assoc Radiol J 2019 Feb;70(1):62-67

Division of Endocrinology, Department of Medicine, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada.

Objective: To determine the incidence of malignancy, follow-up ultrasound (US), and repeat fine needle aspiration (FNA) in thyroid nodules that have been previously biopsied as benign.

Methods: This is a retrospective, descriptive study of benign thyroid nodules evaluated by US between 2010-2011. We determined the frequency of follow-up ultrasounds and FNAs, mean years of follow-up, interval between follow-up US, change in nodule size, reasons for repeat FNA (rFNA), frequency of thyroidectomy, and thyroid malignancy during 5 years of follow-up. Read More

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http://dx.doi.org/10.1016/j.carj.2018.10.001DOI Listing
February 2019
3 Reads

Is thyroid nodule location associated with malignancy risk?

Ultrasonography 2018 Nov 6. Epub 2018 Nov 6.

Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.

Purpose: Nodules located in the upper pole of the thyroid may carry a greater risk for malignancy than those in the lower pole. We conducted a study to analyze the risk of malignancy of nodules depending on location.

Methods: The records of patients undergoing thyroid-nodule fine-needle aspiration cytology (FNAC) at an academic thyroid cancer unit were prospectively collected. Read More

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http://e-ultrasonography.org/journal/view.php?doi=10.14366/u
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http://dx.doi.org/10.14366/usg.18050DOI Listing
November 2018
9 Reads

Ultrasound elastography of the thyroid: principles and current status.

Ultrasonography 2019 Apr 1;38(2):106-124. Epub 2018 Oct 1.

Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, Tongji University School of Medicine, Shanghai, China.

Ultrasound (US) elastography has been introduced as a non-invasive technique for evaluating thyroid diseases. This paper presents a detailed description of the technical principles, peculiarities, and limitations of US elastography techniques, including strain elastography and shear-wave elastography. This review was conducted from a clinical perspective, and aimed to assess the usefulness of US elastography for thyroid diseases in specific clinical scenarios. Read More

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http://dx.doi.org/10.14366/usg.18037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443591PMC

Clinical diagnostic value of contrast-enhanced ultrasound and TI-RADS classification for benign and malignant thyroid tumors: One comparative cohort study.

Medicine (Baltimore) 2019 Jan;98(4):e14051

Department of Ultrasound, Rizhao People's Hospital, Jining Medical University, Shandong Province, PRC.

To evaluate the diagnostic efficacy and clinical value of contrast-enhanced ultrasonography (CEUS) plus TI-RADS classification in benign and malignant thyroid tumors compared with either method alone.The informed consent was signed all patients. A total of 370 patients with thyroid tumors of TI-RADS category 3 and 4 were recruited, with 432 thyroid nodules. Read More

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http://dx.doi.org/10.1097/MD.0000000000014051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358332PMC
January 2019
5.723 Impact Factor

Superb Microvascular Imaging Compared with Contrast-Enhanced Ultrasound for Assessing Laser Ablation Treatment of Benign Thyroid Nodules.

Biomed Res Int 2018 23;2018:1025657. Epub 2018 Dec 23.

Department of Ultrasound, The Third Xiangya Hospital of Central South University, Changsha, Hunan Province 410013, China.

Purpose: To compare superb microvascular imaging (SMI) with contrast-enhanced ultrasonography (CEUS) for evaluating the ablation of benign thyroid nodules.

Methods: 225 Patients with 256 benign thyroid nodules underwent conventional ultrasound, color Doppler flow imaging (CDFI), CEUS, and SMI before and after laser ablation. They were routinely followed up at 1, 3, 6, and 12 months. Read More

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http://dx.doi.org/10.1155/2018/1025657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323482PMC
December 2018
1 Read

Differentiation between benign and malignant thyroid nodules using diffusion-weighted imaging, a 3-T MRI study.

Indian J Radiol Imaging 2018 Oct-Dec;28(4):460-464

Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: Preoperative differentiation of benign from malignant thyroid nodules remains a challenge. Aims: This study assessed the accuracy of diffusion-weighted imaging (DWI) for differentiation between benign and malignant thyroid nodules.

Materials And Methods: Preoperative DWI was performed in patients with thyroid nodule by means of a 3-T scanner magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.4103/ijri.IJRI_488_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319093PMC
January 2019
4 Reads

Comparison among TIRADS (ACR TI-RADS and KWAK- TI-RADS) and 2015 ATA Guidelines in the diagnostic efficiency of thyroid nodules.

Endocrine 2019 Apr 18;64(1):90-96. Epub 2019 Jan 18.

Department of Ultrasound, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, 100730, Beijing, China.

Purpose: To compare the value of Thyroid Imaging Reporting and Data Systems proposed by Kwak (KWAK-TIRADS) and ACR (ACR TI-RADS) and 2015 American Thyroid Association (ATA) guidelines in the diagnosis of surgically resected thyroid nodules.

Methods: From January 2015 to December 2015, 2544 thyroid nodules in 1758 patients who underwent thyroidectomy at our center were included. The KWAK-TIRADS category, ACR TI-RADS and ultrasound (US) pattern based on ATA guidelines were assigned to each thyroid nodule. Read More

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http://dx.doi.org/10.1007/s12020-019-01843-xDOI Listing
April 2019
7 Reads

Non-Local Based Denoising Framework for In Vivo Contrast-Free Ultrasound Microvessel Imaging.

Sensors (Basel) 2019 Jan 10;19(2). Epub 2019 Jan 10.

Department of Radiology, Mayo Clinic College of Medicine & Science, Rochester, MN 55905, USA.

Vascular networks can provide invaluable information about tumor angiogenesis. Ultrafast Doppler imaging enables ultrasound to image microvessels by applying tissue clutter filtering methods on the spatio-temporal data obtained from plane-wave imaging. However, the resultant vessel images suffer from background noise that degrades image quality and restricts vessel visibilities. Read More

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http://www.mdpi.com/1424-8220/19/2/245
Publisher Site
http://dx.doi.org/10.3390/s19020245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358982PMC
January 2019
8 Reads

Non-invasive Amide Proton Transfer Imaging and ZOOM Diffusion-Weighted Imaging in Differentiating Benign and Malignant Thyroid Micronodules.

Front Endocrinol (Lausanne) 2018 12;9:747. Epub 2018 Dec 12.

Department of General Surgery, Guangdong Second Provincial General Hospital, Guangzhou, China.

Pre-operative non-invasive differentiation of benign and malignant thyroid nodules is difficult for doctors. This study aims to determine whether amide proton transfer (APT) imaging and zonally oblique multi-slice (ZOOM) diffusion-weighted imaging (DWI) can provide increased accuracy in differentiating benign and malignant thyroid nodules. This retrospective study was approved by the institutional review board and included 60 thyroid nodules in 50 patients. Read More

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http://dx.doi.org/10.3389/fendo.2018.00747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315121PMC
December 2018
8 Reads

CAD system based on B-mode and color Doppler sonographic features may predict if a thyroid nodule is hot or cold.

Eur Radiol 2019 Jan 9. Epub 2019 Jan 9.

Department of Radiology, Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Objectives: The aim of this study was to evaluate if the analysis of sonographic parameters could predict if a thyroid nodule was hot or cold.

Methods: Overall, 102 thyroid nodules, including 51 hyperfunctioning (hot) and 51 hypofunctioning (cold) nodules, were evaluated in this study. Twelve sonographic features (i. Read More

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http://dx.doi.org/10.1007/s00330-018-5908-yDOI Listing
January 2019
2 Reads

Bilateral papillitis and vitritis as the initial ophthalmologic finding in a patient with complex medical history, leading to diagnosis of multisystem sarcoidosis.

Am J Ophthalmol Case Rep 2019 Mar 21;13:122-126. Epub 2018 Dec 21.

Massachusetts Eye Research and Surgery Institution (MERSI), 1440 Main Street, Suite 201, Waltham, MA, 02451, USA.

Aim: To report a case of bilateral papillitis as the initial ophthalmologic presentation in a patient with complex medical history and multisystemic symptoms, eventually revealing a diagnosis of sarcoidosis.

Methods: Retrospective interventional case report.

Report: A 54-year-old Caucasian woman presented with bilateral decreased vision, photophobia and eye pain for a month. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183024
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http://dx.doi.org/10.1016/j.ajoc.2018.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322055PMC
March 2019
14 Reads