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    Follicular thyroid cancer avid on C-11 Methionine PET/CT.
    Endocrinol Diabetes Metab Case Rep 2018 5;2018. Epub 2018 Jan 5.
    Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.
    A case of follicular thyroid cancer with intense focal Methionine uptake on 11C-Methionine PET/CT is reported here. The use of 11C-Methionine PET in differentiated thyroid cancer is currently being investigated as a surrogate tracer compared to the more widely used 18F-FDG PET. This case illustrates the potential incremental value of this modality, not only in the localizing of parathyroid adenoma, but also indicating that 11C-Methionine PET might have a potential of increasing the pretest likelihood of thyroid malignancy in a cold nodule with highly increased Sestamibi uptake. Read More

    Autonomously hyperfunctioning cystic nodule harbouring thyroid carcinoma - Case report and literature review.
    Int J Surg Case Rep 2018 Jan 8;42:287-289. Epub 2018 Jan 8.
    Department of Surgery, Hospital Pedro Hispano, Rua Dr. Eduardo Torres, 4464-513 Senhora da Hora, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal. Electronic address:
    Introduction: Hyperthyroidism is rarely associated with malignancy, but it cannot rule out thyroid cancer. Although there is published data describing this coexistence, thyroid carcinomas inside autonomously functioning nodules are uncommon.

    Presentation Of Case: A 49-year-old woman presented with a cervical mass, unexplained weight loss and anxiousness, sweating and insomnia. Read More

    Evaluation of pain during high-intensity focused ultrasound ablation of benign thyroid nodules.
    Eur Radiol 2018 Jan 12. Epub 2018 Jan 12.
    Department of Radiology, The University of Hong Kong, Hong Kong, SAR, China.
    Objective: To assess severity and factors of pain during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules.

    Methods: 128 patients who underwent a HIFU ablation for a benign thyroid nodule were analysed. All patients received a bolus of intravenous pethidine and diazepam before treatment. Read More

    Validation of the 2015 American Thyroid Association Management Guidelines for Thyroid Nodules With Benign Cytologic Findings in the Era of the Bethesda System.
    AJR Am J Roentgenol 2018 Jan 11:1-6. Epub 2018 Jan 11.
    1 All authors: Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.
    Objective: The purpose of this study is to investigate follow-up strategies for cytologically benign thyroid nodules according to size and ultrasound (US) pattern according to the 2015 American Thyroid Association (ATA) guidelines in the era of the Bethesda system.

    Materials And Methods: This retrospective study included 1208 patients with 1230 nodules that were cytologically benign at initial fine-needle aspiration performed from June 2012 to December 2014. False-negative rates (FNRs) were calculated by considering nodule size and US pattern according to the 2015 ATA guidelines and were compared between nodules with the high-suspicion US pattern and nodules with the high- or intermediate-suspicion US patterns according to size. Read More

    Upregulated LAMB3 increases proliferation and metastasis in thyroid cancer.
    Onco Targets Ther 2018 21;11:37-46. Epub 2017 Dec 21.
    Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
    Background: Thyroid cancer is the most commonly reported endocrine malignancy, and its increased incidence has been the highest in all human tumors in recent decades. To investigate the mechanism of papillary thyroid cancer (PTC) occurrence and progression, we performed RNA sequencing and found an upregulated gene, LAMB3. However, the biological function of LAMB3 is still not clear. Read More

    Extramedullary hematopoiesis involving the thyroid: A rare cytologic finding in otherwise healthy patients and review of literature.
    J Formos Med Assoc 2018 Jan 6. Epub 2018 Jan 6.
    National Taiwan University College of Medicine, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Center of Anti-Aging and Health Consultation, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
    Background/purpose: The thyroid gland is an uncommon site for the presence of extramedullary hematopoiesis (EMH). We report the cases of four Taiwanese women with hematopoietic elements on the smears of thyroid fine needle aspiration (FNA) samples and compare the findings with those of previously reported cases.

    Methods: We retrieved the data of cases in which thyroid FNA performed between January 2000 and December 2016. Read More

    Histogram analysis of greyscale sonograms to differentiate between the subtypes of follicular variant of papillary thyroid cancer.
    Clin Radiol 2018 Jan 6. Epub 2018 Jan 6.
    Department of Applied Statistics, Chung-Ang University, 221, Heukseok-dong, Dongjak-gu, Seoul 156-756, South Korea.
    Aim: To evaluate the diagnostic value of histogram analysis using ultrasound (US) to differentiate between the subtypes of follicular variant of papillary thyroid carcinoma (FVPTC).

    Materials And Methods: The present study included 151 patients with surgically confirmed FVPTC diagnosed between January 2014 and May 2016. Their preoperative US features were reviewed retrospectively. Read More

    Three-Dimensional Shear Wave Elastography for Differentiating Benign From Malignant Thyroid Nodules.
    J Ultrasound Med 2018 Jan 9. Epub 2018 Jan 9.
    Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, Shanghai, China.
    Objectives: To prospectively evaluate the diagnostic performance of 3-dimensional (3D) shear wave elastography (SWE) for assessing thyroid nodules.

    Methods: A total of 176 surgically or cytologically confirmed thyroid nodules (63 malignant and 113 benign) in 176 patients who had undergone conventional ultrasound (US), 2-dimensional (2D) SWE, and 3D SWE examinations were included in this study. Quantitative elasticity values (mean elasticity, maximum elasticity, and standard deviation of elasticity of a large region of interest and mean elasticity of a 2-mm region of interest) were measured on 2D and 3D SWE. Read More

    Significance of hyperechoic marks observed during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules.
    Eur Radiol 2018 Jan 8. Epub 2018 Jan 8.
    Department of Radiology, The University of Hong Kong, Hong Kong, SAR, China.
    Objective: To examine the association between the appearance of hyperechoic marks (HEMs) during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules and nodule shrinkage at 6 months.

    Methods: One hundred and thirty-six patients who underwent HIFU for benign thyroid nodule were analysed. An independent person carefully examined the B-mode ultrasonography screen for the appearance of HEMs after each pulse. Read More

    Distribution patterns of microcalcifications in suspected thyroid carcinoma: a classification method helpful for diagnosis.
    Eur Radiol 2018 Jan 8. Epub 2018 Jan 8.
    Urology Department, The Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Southern Distinct, Qingdao, Shandong, 266003, China.
    Purpose: The aim of this study was to compare the distribution patterns of microcalcifications in thyroid cancers with benign cases.

    Methods: In total, 358 patients having microcalcifications on ultrasonography were analysed. Microcalcifications were categorised according to the distribution patterns: (I) microcalcifications inside one (a) or more (b) suspected nodules, (II) microcalcifications not only inside but also surrounding a suspected single (a) or multiple (b) nodules, and (III) focal (a) or diffuse (b) microcalcifications in the absence of any suspected nodule. Read More

    Synchronous parathyroid adenoma and papillary thyroid carcinoma: 99mTc-MIBI Scan Findings.
    Niger J Clin Pract 2017 Nov;20(11):1510-1512
    Department of Radiology, Cumhuriyet University Hospital, Sivas, Turkey.
    Simultaneous existence of parathyroid adenoma and thyroid nonmedullary carcinoma is rarely observed. A 52-year-old female was diagnosed approximately 4 years ago with primary hyperparathyroidism (PHPT) on the basis of hypercalcemia and elevated serum parathyroid hormone (PTH) level. Clinically, PHPT diagnosed patient was examined with Tc-99m MIBI scintigraphy to investigate parathyroid adenoma. Read More

    Sonographic measurement of thyroid nodule changes after microwave ablation: relationship between multiple parameters.
    Int J Hyperthermia 2018 Jan 5:1-9. Epub 2018 Jan 5.
    a Department of Ultrasound , Beijing Friendship Hospital, Capital Medical University , Beijing , China.
    Objective: Microwave ablation (MWA) is an effective technique for the treatment of benign thyroid nodules. The aim of this study was to investigate whether it is necessary to study changes in variables other than the volume reduction between follow-up intervals. This study also introduced the index R (Ssurface/V) to explore whether it could reflect features of shape between follow-up intervals. Read More

    Thyroid nodules coexisting with either cystic or solid breast nodules: a new clue for this association between nodules coming from ultrasonography.
    Gland Surg 2017 Dec;6(6):630-637
    Master Program on Childhood, Adolescence and Women's Endocrine Health, University of Messina, Messina, Italy.
    Background: Thyroid and breast nodules (BNs) are common, their prevalence varying based mainly on the population (including age, residence in area of different iodine availability) studied and methods used. The coincidence of thyroid and breast diseases remains controversial and the majority of the studies evaluate the association between breast cancer and thyroid disorders. Here we describe our experience of such association in a non-oncological series. Read More

    An Infrared Thermal Images Database and a New Technique for Thyroid Nodules Analysis.
    Stud Health Technol Inform 2017 ;245:384-387
    Computing Institute, Federal Fluminense University, Niterói, Rio de Janeiro, Brazil.
    Thyroid nodules diseases are a common health problem and thyroidal cancer is becoming increasingly prevalent. They appear in the neck and bottom neck region, superficially over the trachea. Cancer tissues are characterized by higher temperatures than surrounding tissues. Read More

    Comparison of Different-Gauge Needles for Fine-Needle Aspiration Biopsy of Thyroid Nodules.
    J Ultrasound Med 2017 Dec 30. Epub 2017 Dec 30.
    Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
    Objectives: To compare the adequacy of 23-, 25-, and 27-gauge needles in the fine-needle aspiration biopsy of thyroid nodules to develop guidelines for the collection of better specimens for cytologic diagnosis.

    Methods: This randomized prospective study included 156 consecutively enrolled patients with 156 nodules. Each nodule was aspirated with a needle of each size. Read More

    Isolated Scapular Metastasis in a Patient with Malignant Struma Ovarii: A Case Report.
    JBJS Case Connect 2017 Oct-Dec;7(4):e82
    Departments of Orthopaedic Oncology (J.C., F.F.E.P., S.A.N., and W.T.C.), and Pathological Anatomy (F.D.C. and A.D.B.), AC Camargo Cancer Center, São Paulo, Brazil.
    Case: We report the case of a 38-year-old woman who presented with a lytic bone lesion in the left scapula. A biopsy showed a tumor with the histologic appearance of thyroid tissue. She also was found to have a thyroid nodule and an enlarged ovary, both of which were excised. Read More

    The Effect of Electromagnetic Radiation due to Mobile Phone Use on Thyroid Function in Medical Students Studying in a Medical College in South India.
    Indian J Endocrinol Metab 2017 Nov-Dec;21(6):797-802
    Department of Pharmacology, MOSC Medical College, Kolencherry, Ernakulam, Kerala, India.
    Background: Enormous increase in mobile phone use throughout the world raises widespread concerns about its possible detrimental effect on human health. Radiofrequency waves are emitted by cell phones. They are non-ionising and the effect on the thyroid gland is part of their non thermal effects. Read More

    High CEA levels in a case of resected colorectal cancer: delayed diagnosis of metachronous medullary thyroid cancer.
    World J Surg Oncol 2017 Dec 29;15(1):230. Epub 2017 Dec 29.
    School of Medicine, Taipei Medical University and Fu Jen Catholic University, New Taipei City, Taiwan.
    Background: Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers, and its value in the surveillance of post-operative colorectal cancer is well established. Fluorodeoxyglucose-positron emission tomography (FDG-PET) has been clinically used in colorectal cancer imaging including preoperative staging, evaluation of therapeutic response, detection of disease recurrence, and investigation of unexplained rising tumor markers.

    Case Presentation: We report a case of resected colorectal cancer presented with rising CEA levels in 5 years, and FDG-PET revealed no definitive evidence of recurrence except abnormal focal FDG uptake in the right thyroid lobe. Read More

    Superb microvascular imaging (SMI) compared with conventional ultrasound for evaluating thyroid nodules.
    BMC Med Imaging 2017 Dec 28;17(1):65. Epub 2017 Dec 28.
    Department of Ultrasonography, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.
    Background: Superb microvascular imaging (SMI) for depiction of microvascular flow in thyroid nodules was compared with color/power Doppler imaging (CDI/PDI) and contrast-enhanced ultrasonography (CEUS). In addition, the diagnostic performance of conventional ultrasound combined with SMI for differentiating benign and malignant thyroid nodules was evaluated.

    Methods: Preoperative conventional ultrasound consisting of gray-scale ultrasonography and CDI/PDI, followed by SMI and CEUS, was used to record 52 thyroid nodules. Read More

    Non-functioning parathyroid cystic tumour: malignant or not? Report of a case.
    G Chir 2017 Sep-Oct;38(5):243-249
    Parathyroid carcinoma (PC) is a very rare endocrine tumour, usually characterized by symptoms such as a neck mass, dysphonia, severe hypercalcemia exceeding 140 mg/L and elevated serum parathyroid hormone levels, even more than 5 times the upper limit of normal. Non-functioning parathyroid cancer is extremely rare and, in this case, its pre-operative diagnosis is often difficult. A 54-year old female patient, referring dysphagia and dysphonia, underwent neck ultrasound and neck CT. Read More

    Inter-exam agreement and diagnostic performance of the Korean thyroid imaging reporting and data system for thyroid nodule assessment: Real-time versus static ultrasonography.
    Eur J Radiol 2018 Jan 31;98:14-19. Epub 2017 Oct 31.
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University, School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. Electronic address:
    Objective: To investigate the inter-exam agreement for thyroid nodule between real-time ultrasonography (US) assessment and retrospective US interpretation and to compare the diagnostic performance between two methods by using the most recently published guidelines for the US-based management of thyroid nodules, the Korean Thyroid Imaging Reporting and Data System (K-TIRADS).

    Methods: The study included 253 nodules in 238 patients for the inter-exam agreement and 201 nodules in 190 patients for the diagnostic performance. Real-time and retrospectively static US images were analyzed according to the US descriptors and final categories of the K-TIRADS. Read More

    Molecular testing for thyroid nodules: Review and current state.
    Cancer 2017 Dec 26. Epub 2017 Dec 26.
    Department of Otolaryngology, University of Cincinnati, Cincinnati, Ohio.
    Thyroid nodules affect nearly two-thirds of the world population. Fine-needle biopsy with cytologic evaluation remains the diagnostic test of choice to distinguish benign from malignant thyroid nodules yet fails to discriminate as benign or malignant in up to one-third of cases. This review discusses the limitation of current cytopathologic evaluation, the development of thyroid molecular testing, and the strengths and limitations of commercially available tests. Read More

    Comparison Study of the Adequacy and Pain Scale of Ultrasound-Guided Fine-Needle Aspiration of Solid Thyroid Nodules with a 21- or 23-Gauge Needle for Liquid-Based Cytology: a Single-Center Study.
    Endocr Pathol 2017 Dec 23. Epub 2017 Dec 23.
    Department of Radiology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Busan, 51476, South Korea.
    No published study has compared the cytological adequacy between different caliber needles in liquid-based cytology (LBC) after fine-needle aspiration (FNA) of thyroid nodules. This study aimed to compare cytological adequacy, pain scale, and associated complications depending on the use of a 21- and 23-gauge needle in LBC. From January 2017 to April 2017, 88 solid thyroid nodules (STNs) in 88 patients underwent consecutive ultrasonography (US)-guided FNA (US-FNA) by a single radiologist. Read More

    Recent Advances in Core Needle Biopsy for Thyroid Nodules.
    Endocrinol Metab (Seoul) 2017 Dec;32(4):407-412
    Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
    Core needle biopsy (CNB) was introduced as an alternative diagnostic tool to fine-needle aspiration (FNA), and is increasingly being used in the preoperative assessment of thyroid nodules. CNB provides a definitive diagnosis in most cases, but it sometimes may be inconclusive. CNB has the advantage of enabling a histologic examination in relation to the surrounding thyroid tissue, immunohistochemistry, and molecular testing that can provide a more accurate assessment than FNA in selected cases. Read More

    Pleomorphic Adenoma Originating from Heterotopic Salivary Tissue of the Upper Neck: A Diagnostic Pitfall.
    Case Rep Otolaryngol 2017 15;2017:5767396. Epub 2017 Nov 15.
    Division of Radiology, Department of Imaging and Medical Informatics, Geneva University Hospitals, University of Geneva, Geneva, Switzerland.
    Pleomorphic adenoma directly arising in the neck is thought to originate from heterotopic salivary gland tissue. In this article, we present the case of a 55-year-old female patient with a histologically proven pleomorphic adenoma located at the left mandibular angle, anteriorly to the sternocleidomastoid muscle and posteroinferiorly to the submandibular gland. As the patient also had an ipsilateral thyroid nodule with coarse calcifications, clinical and radiological features suggested a possible level II metastatic lymph node. Read More

    Bethesda thyroid categories and family history of thyroid disease.
    Clin Endocrinol (Oxf) 2017 Dec 20. Epub 2017 Dec 20.
    University Hospital Center "Sestre Milosrdnice", Department of Oncology and Nuclear Medicine, Vinogradska cesta 29, 10000, Zagreb, Croatia.
    Objective: Thyroid cancer is the most common type of endocrine-related cancer worldwide. The aim of this article was to assess the relationship between thyroid diseases diagnosed by fine needle aspiration (FNA) and family history of thyroid disease.

    Design: The study was conducted in a tertiary high-volume thyroid cancer center. Read More

    An Unusual Case of Metastatic Functional Thyroid Carcinoma With a Remarkable Treatment Response to Radioactive Iodine.
    J Endocr Soc 2017 Dec 8;1(12):1440-1444. Epub 2017 Aug 8.
    Division of Endocrinology, Department of Medicine, Montefiore Medical Center, Bronx, New York 10467.
    Functional thyroid carcinoma is an unusual cause of thyrotoxicosis. We describe the clinical presentation and treatment of a patient with thyrotoxicosis due to functional thyroid carcinoma and Graves disease, and discuss potential mechanisms causing the thyrotoxicosis. A 79-year-old woman with a remote history of hemithyroidectomy and current hyperthyroidism came to the hospital with upper and lower extremity weakness. Read More

    Cytologic features of primary monophasic synovial sarcoma of the thyroid gland.
    Cytojournal 2017 12;14:24. Epub 2017 Oct 12.
    Address: Department of Pathology, Chonnam National University Medical School, Gwangju, Republic of Korea.
    Synovial sarcoma (SS) is a rare soft tissue tumor, commonly arising in para-articular areas of extremities, but can also present in the head and neck area. However, primary SS of the thyroid gland is an extremely rare tumor which has been reported only five times in previous English literatures. This report presents fine needle aspiration (FNA) cytology of primary monophasic SS of the thyroid gland. Read More

    [Differentiated thyroid cancer in children and adolescents: about 22 cases].
    Pan Afr Med J 2017 25;28:71. Epub 2017 Sep 25.
    Service ORL et Chirurgie Cervico-faciale, Hôpital 20 Août, Casablanca, Maroc.
    This study aimed to highlight the features of thyroid cancer in children and adolescents and to evaluate our results compared to the international literature on the basis of the most representative case series in Morocco: 22 cases. We conducted a retrosective study of patients with differentiated thyroid cancer hospitalized in the otorhinolaryngology and cervicofacial surgery department at the Hôpital 20 Août, Casablanca, Morocco over the period January 1995-March 2015. We collected data on 22 cases that met our inclusion criteria. Read More

    Genetic testing for indeterminate thyroid cytology: meta-analysis and review.
    Endocr Relat Cancer 2017 Dec 18. Epub 2017 Dec 18.
    H Gonzalez, Department of Surgical Oncology, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Thyroid cancer is the most frequent endocrine malignancy, and its incidence is increasing. A current limitation of cytological evaluation of thyroid nodules is that 20-25% are reported as indeterminate. Therefore, an important challenge for clinicians is to determine whether an indeterminate nodule is malignant, and should undergo surgery, or benign, and should be recommended to follow-up. Read More

    Distinguishing benign from malignant thyroid nodules using thyroid ultrasonography: utility of adding superb microvascular imaging and elastography.
    Radiol Med 2017 Dec 16. Epub 2017 Dec 16.
    Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 84 Heukseok-Ro, Dongjak-Gu, Seoul, 06973, Republic of Korea.
    Objective: Thyroid nodules are common; however, malignancy is less than 7%. Therefore, additional techniques such as Doppler ultrasonography or elastography are used to improve diagnostic performance of conventional ultrasonography. We want to prospectively investigate the use of additional superb microvascular imaging (SMI) and strain elastography to B-mode ultrasound in thyroid nodules in distinguishing benign from malignant thyroid nodules. Read More

    Lung adenocarcinoma and pulmonary metastases coexist in a patient with papillary thyroid carcinoma: A case report.
    Medicine (Baltimore) 2017 Dec;96(49):e9078
    aDepartment of Radiation Oncology, the Third Affiliated Hospital of Soochow University, Changzhou, ChinabDepartment of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinacDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, China.
    Rationale: Multiple primary malignant tumors (MPMTs) are defined as 2 or more independent primary malignancies of different histologies/origins in the same individual. Although the incidence of MPMTs is being increasing, second primary cancer (SPC) is still rare and difficult to distinguish from metastasis. Here, we present a case of thyroid carcinoma with lung metastasis and primary lung cancer. Read More

    Evidence based management of incidental focal uptake of fluorodeoxyglucose on PET-CT.
    Br J Radiol 2017 Dec 15:20170774. Epub 2017 Dec 15.
    2 Department of Nuclear Medicine, Royal Free Hospital NHS Foundation Trust, London, UK.
    Focal incidental uptake, with or without CT abnormalities, is a common finding on FDG PET/CT and evidence based management for this type of uptake is lacking. This article reviews the evidence on focal incidental uptake including the incidence of malignancy, differential diagnosis and imaging criteria which can be used to further characterise it. The article focusses on PET rather than CT criteria. Read More

    Transoral thyroidectomy: a viable surgical option with unprecedented complications-a case series.
    J Endocrinol Invest 2017 Dec 14. Epub 2017 Dec 14.
    Department of Surgical Pathology, The University of Pisa, 56124, Pisa, Italy.
    Purpose: To report the clinical implications of an initial experience with transoral endoscopic thyroidectomy vestibular approach (TOETVA).

    Methods: From March to November 2017, five cases of TOETVA were performed. Data reported include patient demographics, indication for surgery, extent of surgery, operative time, the need to convert to cervicotomy, the length of hospital stay and post-operative pain and morbidity. Read More

    Natural History of Contralateral Nodules after Lobectomy in Patients with Papillary Thyroid Carcinoma.
    J Clin Endocrinol Metab 2017 Dec 12. Epub 2017 Dec 12.
    Endocrine Institute, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
    Background: Bilateral thyroid nodularity is considered an indication for total thyroidectomy in papillary thyroid carcinoma (PTC) patients. However, the natural history and outcome of contralateral nodules has never been studied.

    Objective: To investigate the natural history of non-suspicious contralateral nodules after lobectomy for PTC. Read More

    Comparative analysis of 2 robotic thyroidectomy procedures: Transoral versus bilateral axillo-breast approach.
    Head Neck 2017 Dec 14. Epub 2017 Dec 14.
    Department of Otolaryngology - Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
    Background: The surgical outcomes of a single surgeon's initial cases of transoral robotic thyroidectomy (TORT) were compared with the surgeon's initial cases of a bilateral axillo-breast approach (BABA) robotic thyroidectomy.

    Methods: The medical reports were retrospectively reviewed. The BABA robotic thyroidectomies were performed between 2008 and 2009, and TORTs were performed between 2012 and 2016. Read More

    Acinic Cell Carcinoma of the Parotid Gland in Children and Adolescents.
    J Pediatr Hematol Oncol 2017 Dec 12. Epub 2017 Dec 12.
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
    Acinic cell carcinoma of the parotid gland is a rare low-grade malignant neoplasm. Data on children are sparse. For the present study, the database of a tertiary pediatric medical center was reviewed for all patients with parotid gland acinic cell carcinoma diagnosed and treated between 2004 and 2013. Read More

    Initial clinical presentation of single soft tissue metastasis of medullary thyroid carcinoma without primary tumor in the thyroid gland.
    World J Surg Oncol 2017 Dec 13;15(1):221. Epub 2017 Dec 13.
    Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto Nagano, 390-8621, Japan.
    Background: Single soft tissue metastasis of medullary thyroid carcinoma is extremely rare. In addition, several occult medullary thyroid carcinomas with distant metastasis were reported, but undetectable primary lesion at diagnosis was also extremely rare.

    Case Presentation: A 74-year-old man was admitted to our hospital because of a painful nodule in his left buttock for over 1 year. Read More

    Insight into Differentiated Thyroid Cancer Gross Pathological Specimen Shrinkage and Its Influence on TNM Staging.
    Eur Thyroid J 2017 Nov 26;6(6):315-320. Epub 2017 Jul 26.
    Polyclinique Les Fleurs, Service Imagerie Médicale, Ollioules, France.
    Introduction: This study aimed at comparing thyroid cancer staging when taking into account the differences between the "T" assessment" using ultrasound (US) and histopathological measurements.

    Material And Methods: This retrospective study included all consecutive differentiated follicular thyroid cancer (DTC) and medullary thyroid cancer (MTC) patients who underwent postoperative histopathological staging assessment at a single institution. Anaplastic thyroid carcinomas were excluded from the present study. Read More

    Incidental Detection of Occult Thyroid Carcinoma with 11C-Choline PET/CT for High Risk Prostate Cancer.
    Curr Urol 2017 Nov 22;10(4):217-220. Epub 2017 Oct 22.
    Department of Urology, University Hospitals Leuven, Belgium.
    We report a case of a 65-year-old male patient with high-risk prostate cancer, re-staged with 11C-choline positron emission tomography/computed tomography (PET/CT) for prostate specific antigen recurrences 3 years after radical prostatectomy and adjuvant radiation therapy. In addition to 2 suspicious presacral lymph nodes which were resected and proven to be metastatic, PET/CT revealed a very high uptake in a calcified thyroid nodule. Evaluation with fine needle aspiration was suspicious for thyroid carcinoma and the patient underwent total thyroidectomy, confirming a non-metastatic encapsulated follicular variant of papillary thyroid carcinoma. Read More

    Invasive Insular Thyroid Carcinoma Presenting as Nonparalytic Dysphonia.
    Ochsner J 2017 ;17(4):438-441
    Department of Otolaryngology, Ochsner Clinic Foundation, New Orleans, LA.
    Background: Patients with suspected thyroid malignancy often undergo preoperative laryngeal examination with a focus on vocal fold mobility. We present the unique case of a patient with invasive thyroid carcinoma who presented with dysphonia despite intact vocal fold motion.

    Case Report: A 73-year-old female with a remote thyroid lobectomy presented with dysphonia. Read More

    Type 2 diabetes mellitus is more prevalent among patients with thyroid carcinoma and influences overall survival: a propensity score matching analysis.
    Oncotarget 2017 Nov 31;8(57):97528-97536. Epub 2017 Oct 31.
    Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
    The relationship between Type 2 Diabetes Mellitus(T2DM) and cancer risk has been investigated for more than a decade. Many types of cancer were confirmed to be related with T2DM. The aim of this study is to identify the relationship between T2DM and the prevalence and long-term survivals of Thyroid Carcinoma(TC) using propensity score matching. Read More

    Logistic regression analysis of conventional ultrasonography, strain elastosonography, and contrast-enhanced ultrasound characteristics for the differentiation of benign and malignant thyroid nodules.
    PLoS One 2017 11;12(12):e0188987. Epub 2017 Dec 11.
    Health Science Center, Shenzhen University, Shenzhen 518060, China.
    The aim of the study is to screen the significant sonographic features by logistic regression analysis and fit a model to diagnose thyroid nodules. A total of 525 pathological thyroid nodules were retrospectively analyzed. All the nodules underwent conventional ultrasonography (US), strain elastosonography (SE), and contrast -enhanced ultrasound (CEUS). Read More

    Parathyroid carcinoma occurred in two glands in multiple endocrine neoplasia 1: a report on a rare case.
    Endocr J 2017 Dec 8. Epub 2017 Dec 8.
    Department of Breast and Endocrine Surgery, Tokyo Women's Medical University, Tokyo, Japan.
    Primary hyperparathyroidism is the most common hormonal manifestation associated with multiple endocrine neoplasia 1 (MEN1). It is generally caused by parathyroid hyperplasia, and parathyroid carcinoma is rare. Here, we report a case of MEN1 with parathyroid carcinoma in two parathyroid glands causing primary hyperparathyroidism. Read More

    Comparison of Ultrasound-Guided Percutaneous Polidocanol Injection Versus Percutaneous Ethanol Injection for Treatment of Benign Cystic Thyroid Nodules.
    J Ultrasound Med 2017 Dec 8. Epub 2017 Dec 8.
    Department of Endocrinology and Metabolism, First Affiliated Hospital of Soochow University, Suzhou, China.
    Objectives: We compared the efficacy, safety, and cost-effectiveness of ultrasound-guided percutaneous polidocanol injection and percutaneous ethanol injection for the treatment of benign cystic and predominantly cystic thyroid nodules.

    Methods: A total of 135 cystic thyroid nodules treated by percutaneous ethanol injection and 136 cystic thyroid nodules treated by percutaneous polidocanol injection were enrolled retrospectively in this study from May 2010 to March 2016. The nodules were followed after 1, 3, 6, and 12 months. Read More

    "Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features" With Focal Spindle Cell Metaplasia.
    Int J Surg Pathol 2017 Dec 1:1066896917741548. Epub 2017 Dec 1.
    1 Geneva University Hospital, Geneva, Switzerland.
    "Noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) is a recent reclassification of the encapsulated follicular variant of papillary thyroid carcinoma, which is supposed to reflect its indolent clinical behavior and to prevent overtreatment of patients with this neoplasm. The diagnosis of NIFTP can only be made histologically on the surgical specimen according to specific inclusion and exclusion criteria, which requires the examination of the whole nodule and its capsule. Spindle cell proliferations, especially of follicular cell origin, arising within thyroid follicular neoplasms are very rare and may cause diagnostic difficulties. Read More

    Diagnostic accuracy of [99mTc]Tc-Sestamibi in the assessment of thyroid nodules.
    Oncotarget 2017 Nov 17;8(55):94681-94691. Epub 2017 Oct 17.
    Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
    [99mTc]Tc-Sestamibi (MIBI) is an increasingly used tool for evaluation of thyroid nodules. However, there is a lack of evidence about the accuracy of this method in the European population. The aim of this study was to assess the utility of MIBI for the differentiation of thyroid nodules in a large cohort. Read More

    The efficacy and safety of high-intensity focused ultrasound ablation of benign thyroid nodules.
    Ultrasonography 2017 Oct 10. Epub 2017 Oct 10.
    Department of Surgery, Queen Mary Hospital, University of Hong Kong, Hong Kong, China.
    High-intensity focused ultrasound (HIFU) is a promising form of thermal ablation of benign thyroid nodules, but evidence supporting its use is scarce. The present review evaluated the efficacy and safety of single-session HIFU treatment of benign thyroid nodules. As reported in the literature, the extent of nodule shrinkage following treatment ranged from 48. Read More

    The impact of repeat FNA in non-diagnostic and indeterminate thyroid nodules: A 5-year single-centre experience.
    Cytopathology 2017 Dec 4. Epub 2017 Dec 4.
    Municipal University of São Caetano, São Caetano do Sul, Brazil.
    Introduction: FNA is a well-established method for the preoperative diagnosis of thyroid nodules, but limitations still reside among non-diagnostic and indeterminate samples. The objective of the present study was to assess the impact of repeat FNA in thyroid nodules primarily classified as non-diagnostic and indeterminate, with the evaluation of the diagnostic resolution rate after the reassessment of the nodule.

    Methods: We retrospectively collected all cases of thyroid FNA at our institution in the last 5 years that had one or more repeat aspirations of the same nodule, calculating the percentage of samples with change in the diagnostic category. Read More

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