10,035 results match your criteria Thyroid Nodule


Cost-effectiveness of routine calcitonin screening and fine-needle aspiration biopsy in preoperative diagnosis of medullary thyroid Cancer in the United States.

Oral Oncol 2020 Jul 8;110:104878. Epub 2020 Jul 8.

Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA, USA; Division of Thyroid and Parathyroid Endocrine Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

Objectives: examine the cost-effectiveness of routine Calcitonin (Ctn) screening test in the United States.

Materials And Methods: Markov chain model was developed that compares fine-needle aspiration biopsy (FNAB) with Ctn screening vs. FNAB-only in the evaluation of a thyroid nodule with non-highly suspicious findings. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2020.104878DOI Listing

Radiomics Based on Thyroid Ultrasound Can Predict Distant Metastasis of Follicular Thyroid Carcinoma.

J Clin Med 2020 Jul 8;9(7). Epub 2020 Jul 8.

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.

We aimed to evaluate whether radiomics analysis based on gray-scale ultrasound (US) can predict distant metastasis of follicular thyroid cancer (FTC). We retrospectively included 35 consecutive FTCs with distant metastases and 134 FTCs without distant metastasis. We extracted a total of 60 radiomics features derived from the first order, shape, gray-level cooccurrence matrix, and gray-level size zone matrix features using US imaging. Read More

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http://dx.doi.org/10.3390/jcm9072156DOI Listing

Knowledge-guided synthetic medical image adversarial augmentation for ultrasonography thyroid nodule classification.

Comput Methods Programs Biomed 2020 Jun 30;196:105611. Epub 2020 Jun 30.

College of Information and Computer, Taiyuan University of Technology, Taiyuan, China.

Background And Objective: Image classification is an important task in many medical applications. Methods based on deep learning have made great achievements in the computer vision domain. However, they typically rely on large-scale datasets which are annotated. Read More

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http://dx.doi.org/10.1016/j.cmpb.2020.105611DOI Listing

Rare presentation of metastatic renal cell carcinoma to thyroid gland: A case report.

Ann Med Surg (Lond) 2020 Aug 20;56:194-196. Epub 2020 Jun 20.

Department of Otolaryngology Head and Neck Surgery, King Abdullah Medical City, Makkah, Saudi Arabia.

Introduction: Renal cell carcinoma is known to cause metastasis to unusual sites, but metastasis to the thyroid gland is a rare occurrence, not only that, but 20 years after complete recovery is almost nonexistent.

Case Presentation: We are presenting here a case of 79-year-old female who presented to us for asymptomatic progressive thyroid nodule. She had history of right nephrectomy for renal cell carcinoma 20 years ago. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334792PMC

Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study.

Endocrine 2020 Jul 7. Epub 2020 Jul 7.

Thyroid and Endocrine Tumors Unit, Institute of Endocrinology, Pitié Salpêtrière Hospital, IUC Sorbonne University, Paris, France.

Purpose: The aim of this prospective study (ClinicalTrials.gov: NCT01880203) was to evaluate the diagnostic and prognostic value of a 7-panel mutation testing in the aspirates of thyroid nodules with indeterminate cytology (IC).

Methods: Eligible patients had a thyroid nodule ≥15 mm with IC (Bethesda III-V) for which surgery had been recommended. Read More

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http://dx.doi.org/10.1007/s12020-020-02411-4DOI Listing

Applying Amide Proton Transfer-Weighted Imaging (APTWI) to Distinguish Papillary Thyroid Carcinomas and Predominantly Solid Adenomatous Nodules: Comparison With Diffusion-Weighted Imaging.

Front Oncol 2020 19;10:918. Epub 2020 Jun 19.

The Department of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou, China.

Amide proton transfer-weighted (ATPw) imaging is a novel MRI technique that has been used to identify benign and malignant tumors. The present study evaluated the role of APTw imaging in differentiating papillary thyroid carcinoma from predominantly solid adenomatous nodule. This study included 24 cases of solitary papillary thyroid carcinoma, and 20 cases of solid adenomatous nodules. Read More

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http://dx.doi.org/10.3389/fonc.2020.00918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317983PMC

[Thyroid nodules: The Guidelines of the American Thyroid Association from a European Perspective].

Dtsch Med Wochenschr 2020 Jul 7. Epub 2020 Jul 7.

In Germany and in other regions with former iodine deficiency, thyroid nodules and nodular goiter are still much more frequent than in the U.S.A. Read More

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http://dx.doi.org/10.1055/a-1018-2767DOI Listing

Texture Synthesis Based Thyroid Nodule Detection From Medical Ultrasound Images: Interpreting and Suppressing the Adversarial Effect of In-place Manual Annotation.

Front Bioeng Biotechnol 2020 17;8:599. Epub 2020 Jun 17.

Hongqiao International Institute of Medicine, Shanghai Tong Ren Hospital and Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Deep learning method have been offering promising solutions for medical image processing, but failing to understand what features in the input image are captured and whether certain artifacts are mistakenly included in the model, thus create crucial problems in generalizability of the model. We targeted a common issue of this kind caused by manual annotations appeared in medical image. These annotations are usually made by the doctors at the spot of medical interest and have adversarial effect on many computer vision AI tasks. Read More

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http://dx.doi.org/10.3389/fbioe.2020.00599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311795PMC

Can patients find an Endocrine Surgeon? How hospital websites hide the expertise of these medical professionals.

Am J Surg 2020 Jun 19. Epub 2020 Jun 19.

Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address:

Background: With information on healthcare providers available on the internet, patient self-referral has become popular. This study serves to evaluate the ease with which patients can locate an Endocrine Surgeon using hospital websites.

Methods: Websites of the 16 top academic hospitals from The US News and World Report's Hospital Rankings for 2018-2019 were accessed. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2020.06.016DOI Listing

Discordance Between the American Thyroid Association and the American College of Radiology Guideline Systems for Thyroid Nodule Biopsy.

J Surg Res 2020 Jun 30;255:469-474. Epub 2020 Jun 30.

Division of Surgical Oncology, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address:

Background: Previously, fine-needle aspiration biopsy was recommended for any thyroid nodule >1.0 cm in size. In 2015, the American Thyroid Association (ATA) introduced a pattern-based approach for biopsy recommendations based on size and ultrasound (US) characteristics. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.074DOI Listing

Sensory change in the chin and neck after transoral thyroidectomy: Prospective study of mental nerve injury.

Head Neck 2020 Jul 4. Epub 2020 Jul 4.

Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, South Korea.

Background: The study aimed to evaluate the sensory changes on the chin and neck in transoral thyroidectomy.

Methods: We prospectively assessed the cutaneous sensation of 10 zones of the chin, face, and neck in 43 patients who underwent transoral robotic or endoscopic thyroidectomy using the Semmes-Weinstein monofilaments test, preoperatively and postoperatively at 1 week, 1 month, and 3 months.

Results: The sensation of the chin and lower lip did not differ before and after surgery. Read More

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http://dx.doi.org/10.1002/hed.26351DOI Listing

Vital volume increase versus clinical evaluation as the indication of additional radiofrequency ablation for benign thyroid nodule: a single center retrospective study.

Int J Hyperthermia 2020 ;37(1):777-785

Department of Ultrasound, First Medical Center, Chinese PLA General Hospital, Beijing, China.

To compare results in patients treated with additional radiofrequency ablation (RFA) after clinical evaluation or vital volume (Va) increase. Forty patients with 42 benign thyroid nodules who underwent additional RFA were evaluated in this retrospective study. According to the different indication for additional RFA, 18 patients were divided into Vv increase group (V group) and 22 into clinical evaluation group (C group). Read More

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http://dx.doi.org/10.1080/02656736.2020.1778197DOI Listing
January 2020

[Anhydrous Ethanol Improves Efficiency of Radiofrequency Ablation for the Treatment of Benign Thyroid Nodules:A Prospective Randomized Controlled Trial].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 Jun;42(3):331-337

Department of Ultrasound,Chinese PLA General Hospital,Beijing 100853,China.

To investigate the value of injecting a small amount of absolute ethanol into the benign solid nodules of the thyroid before radiofrequency ablation(RFA)to improve the efficiency of radiofrequency ablation. A total of 98 eligible patients(98 nodules)with pathologically confirmed benign solid nodules who were treated in our center from December 2016 to February 2018 were included and randomized into ethanol ablation(EA)combined with radiofrequency ablation(RFA)group(EA+RFA group)and RFA group,with 49 patients in each group.Routine ultrasound,contrast-enhanced ultrasound(CEUS),and thyroid function test were performed before treatment and 1,3,6,and 12 months after treatment. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.11512DOI Listing

Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation.

Endocrinol Metab (Seoul) 2020 Jun 24;35(2):407-415. Epub 2020 Jun 24.

Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose in water (5% DW) can reduce nerve damage during RFA. This study validated the efficacy of injecting cold 5% DW for management of nerve damage during RFA. Read More

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http://dx.doi.org/10.3803/EnM.2020.35.2.407DOI Listing

Serum Adiponectin and Progranulin Level in Patients with Benign Thyroid Nodule or Papillary Thyroid Cancer.

Endocrinol Metab (Seoul) 2020 Jun 24;35(2):396-406. Epub 2020 Jun 24.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul, Korea.

Background: Obesity is associated with thyroid cancer risk. Adiponectin has insulin-sensitizing and anti-inflammatory effects, while progranulin is associated with inflammation and tumorigenesis. We investigated serum adiponectin and progranulin levels in patients with benign thyroid nodule (benign group) and papillary thyroid cancer (PTC; PTC group). Read More

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http://dx.doi.org/10.3803/EnM.2020.35.2.396DOI Listing

Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.

Endocrinol Metab (Seoul) 2020 Jun 24;35(2):339-350. Epub 2020 Jun 24.

Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: Ultrasound-guided thermal ablations have become one of the main options for treating benign thyroid nodules. To determine efficacy of thermal ablation of benign thyroid nodules, we performed a meta-analysis of studies with long-term follow-up of more than 3 years.

Methods: Databases were searched for studies published up to August 25, 2019, reporting patients with benign thyroid nodules treated with thermal ablation and with follow-up data of more than 3 years. Read More

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http://dx.doi.org/10.3803/EnM.2020.35.2.339DOI Listing

Case Report: Familial Hypocalciuric Hypercalcaemia and Hashimoto's Thyroiditis.

Front Surg 2020 16;7:30. Epub 2020 Jun 16.

Department of Transplant and Endocrine Surgery, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

Hypercalcaemia can be caused by many disorders. Primary hyperparathyroidism is the leading cause with parathyroidectomy being the definitive management. Familial hypocalciuric hypercalcaemia is a rarer cause in which resection of the parathyroid tissue does not result in normalized serum calcium. Read More

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http://dx.doi.org/10.3389/fsurg.2020.00030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308482PMC

Plasma Metabolic Profiling of Human Thyroid Nodules by Gas Chromatography-Mass Spectrometry (GC-MS)-Based Untargeted Metabolomics.

Front Cell Dev Biol 2020 16;8:385. Epub 2020 Jun 16.

Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

One of the challenges in the area of diagnostics of human thyroid cancer is a preoperative diagnosis of thyroid nodules with indeterminate cytology. Herein, we report an untargeted metabolomics analysis to identify circulating thyroid nodule metabolic signatures, to find new novel metabolic biomarkers. Untargeted gas chromatography-quadrupole-mass spectrometry was used to ascertain the specific plasma metabolic changes of thyroid nodule patients, which consisted of papillary thyroid carcinoma (PTC; = 19), and multinodular goiter (MNG; = 16), as compared to healthy subjects ( = 20). Read More

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http://dx.doi.org/10.3389/fcell.2020.00385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308550PMC

[Etiological diagnosis of thyroid nodules : collaborative approach between the internist and specialists].

Rev Med Suisse 2020 Jul;16(699):1311-1315

Service de médecine, Hôpital de Nyon, Groupement hospitalier de l'Ouest lémanique (GHOL), Chemin Monastier 10, 1260 Nyon.

One or more thyroid nodules, most often asymptomatic, may be found in more than half of the population, and they usually do not require specific therapeutic management, except for cancerous nodules. In order to avoid under-diagnosis and over-treatment, we propose a diagnostic strategy in line with current recommendations, based on the collaboration between general internist, radiologist, and endocrinologist. In addition to clinical information and thyroid function tests, thyroid ultrasound remains the first step in assessing the risk of nodule malignancy and setting the indication for fine needle aspiration. Read More

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Nodule Localization in Thyroid Ultrasound Images with a Joint-Training Convolutional Neural Network.

J Digit Imaging 2020 Jun 30. Epub 2020 Jun 30.

Department of Ultrasound, Fudan University Shanghai Cancer Center, Shanghai, China.

The accurate localization of nodules in ultrasound images can convey crucial information to support a reliable diagnosis. However, this is usually challenging due to low contrast and image artifacts, especially in thyroid ultrasound images where nodules are relatively small in most cases. To address these problems, in this paper, we propose a joint-training convolutional neural network (CNN) for thyroid nodule localization in ultrasound images. Read More

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http://dx.doi.org/10.1007/s10278-020-00366-6DOI Listing

Taller-than-wide Thyroid Nodules With Microcalcifications Are at High Risk of Malignancy.

In Vivo 2020 Jul-Aug;34(4):2101-2105

Medical Diagnosis Group, Athens, Greece

Background/aim: Previous studies have shown that there may be a diversity in the ultrasonographic (US) features discriminating a malignant from a benign thyroid nodule. We determined the reliability of the specific nodule shape in combination with other US features in predicting thyroid carcinomas.

Patients And Methods: This was a retrospective single-center study investigating the association of the morphological characteristics of nodular goiters from preoperative US and color Doppler images with malignancy based on pathology. Read More

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http://dx.doi.org/10.21873/invivo.12014DOI Listing

Case of aggressive metastatic follicular variant papillary thyroid carcinoma with BRAF K601E and BCORL1 mutations.

BMJ Case Rep 2020 06 30;13(6). Epub 2020 Jun 30.

Department of Endocrinology, Diabetes, and Metabolism, Mayo Clinic Florida, Jacksonville, Florida, USA.

BCL6 corepressor like-1 (BCORL1) mutation has rarely been described in thyroid cancer or in association with BRAF mutations in any malignancy. However, we report a 49-year-old woman who had aggressive follicular variant papillary thyroid carcinoma (FV-PTC) with both the BRAF K601E and BCORL1 mutations. The patient underwent a total thyroidectomy for a 3. Read More

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http://dx.doi.org/10.1136/bcr-2019-234208DOI Listing

The Association Between Hyperhomocysteinemia and Thyroid Nodule Prevalence in an Adult Population.

Metab Syndr Relat Disord 2020 Jun 29. Epub 2020 Jun 29.

Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Thyroid nodule is the most common disorder of thyroid. Metabolic syndrome was regarded as an important factor for the prevalence of thyroid nodule. Homocysteine has been shown to be related to metabolic syndrome, inflammation, and several common cancers. Read More

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http://dx.doi.org/10.1089/met.2020.0057DOI Listing

Incidental detection of unexpected neck lymphatic III level node metastasis from occult papillary thyroid carcinoma during cervical disc surgery: first literature report.

Endokrynol Pol 2020 Jun 29. Epub 2020 Jun 29.

Pathology Department, District Hospital, Arkonska 4, 71-455 Szczecin, Poland.

Background: The regional lymph node metastases of papillary thyroid carcinoma are very common. Subclinical neck lymphatic malignancy of the undiagnosed papillary carcinoma can be found by chance at autopsy or intravitally, especially during neck imaging scrutiny for other reasons. And cervical lymph node metastasis as the initial manifestation of occult papillary thyroid carcinoma is very rare phenomenon. Read More

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http://dx.doi.org/10.5603/EP.a2020.0031DOI Listing

Prevalence and diagnostic significance of noninvasive follicular thyroid neoplasm with papillary-like nuclear features among tumors previously diagnosed as follicular adenoma: a single-institutional study in Japan.

Endocr J 2020 Jun 26. Epub 2020 Jun 26.

Department of Surgery, Kuma Hospital, 8-2-35 Shimoyamate-dori, Chuo-ku, Kobe, Hyogo 650-0011, Japan.

The incidence of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in papillary thyroid carcinoma (PTC) is significantly lower in Asian countries than Western countries; however, the difference remains unexplained. This study aimed to evaluate the incidence of NIFTP in tumors diagnosed as follicular adenoma (FA) in a Japanese institution and discuss the significance of NIFTP. In this study, 44 tumors were investigated, which were histologically diagnosed as FA at the Kuma Hospital in 2008. Read More

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http://dx.doi.org/10.1507/endocrj.EJ20-0198DOI Listing

Malignancy risk of thyroid nodules with nonshadowing echogenic foci.

Ultrasonography 2020 Apr 19. Epub 2020 Apr 19.

Department of Pathology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

Purpose: This study was conducted to determine the malignancy risk and diagnostic value of various types of nonshadowing echogenic foci (NEF) in the risk stratification of thyroid nodules.

Methods: A total of 1,018 consecutive thyroid nodules (≥1 cm) with final diagnoses were included. The presence of NEF was determined and types of NEF were classified according to the presence of a comet tail artifact (CTA), location, and size through a prospective evaluation. Read More

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http://dx.doi.org/10.14366/usg.20012DOI Listing

The correlation between ultrasonographic features, bFGF, and the local invasiveness of thyroid papillary carcinoma.

Medicine (Baltimore) 2020 Jun;99(26):e20644

Department of Ultrasound.

The present study aimed to investigate the correlation between ultrasonographic features, basic fibroblast growth factor (bFGF), and the local invasiveness of papillary thyroid carcinoma (PTC).A total of 350 samples of thyroid nodules were collected. Routine ultrasonography was performed before the operation and routine pathological diagnosis and bFGF detection were performed after the operation. Read More

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http://dx.doi.org/10.1097/MD.0000000000020644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328907PMC

The Diagnostic Role of Computed Tomography for ACR TI-RADS 4-5 Thyroid Nodules With Coarse Calcifications.

Front Oncol 2020 5;10:911. Epub 2020 Jun 5.

Department of Radiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Coarse calcifications are prone to cause echo attenuation during ultrasonography (US) and hence affect the classification of benign and malignant nodules. This study aimed to investigate the diagnostic role of computed tomography (CT) for differentiating the American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS) 4-5 nodules with coarse calcifications. CT data of 216 ACR TI-RADS 4-5 nodules with coarse calcifications confirmed by surgery and pathology in 207 patients were analyzed retrospectively. Read More

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http://dx.doi.org/10.3389/fonc.2020.00911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289989PMC

Comparison of Ultrasonography Features and K-TIRADS for Isthmic and Lobar Papillary Thyroid Carcinomas: A Single-Center Study.

Front Endocrinol (Lausanne) 2020 4;11:328. Epub 2020 Jun 4.

Department of Radiology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, South Korea.

This study aimed to compare ultrasonography (US) features and the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS) categories for diagnosing isthmic and lobar papillary thyroid carcinomas (PTC). From January 2009 to December 2012, 163 patients who underwent thyroid surgery and were confirmed with a post-operative histopathological diagnosis of isthmic PTC were retrospectively included. Fifty-nine patients were excluded because their tumor size was <0. Read More

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http://dx.doi.org/10.3389/fendo.2020.00328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287017PMC

Relations of prediabetes and type 2 diabetes to the thyroid cancer.

Endocr Connect 2020 Jun 1. Epub 2020 Jun 1.

M Hill, Institute of Endocrinology, Institute of Endocrinology, Praha, Czech Republic.

Objective: Patients with type 2 diabetes (T2DM) generally experience a higher incidence of cancer. However, the association between T2DM and thyroid cancer is inconclusive.

Methods: Case-control prospective study, 722 patients were screened for T2DM and prediabetes (PDM) and underwent thyroid ultrasound and biochemical tests. Read More

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http://dx.doi.org/10.1530/EC-20-0180DOI Listing

Effect of the location and size of thyroid nodules on the diagnostic performance of ultrasound elastography: A retrospective analysis.

Clinics (Sao Paulo) 2020 22;75:e1720. Epub 2020 Jun 22.

Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China, 230022.

Objectives: Ultrasound-guided fine-needle aspiration biopsies are recommended for the detection of suspicious thyroid nodules. However, the best approach regarding suspicious ultrasound features for thyroid nodules is still unclear. This study aimed to evaluate the effect of location and size of thyroid nodules on the diagnostic performance of strain ultrasound elastography. Read More

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http://dx.doi.org/10.6061/clinics/2020/e1720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297523PMC

Use of strain ultrasound elastography versus fine-needle aspiration cytology for the differential diagnosis of thyroid nodules: a retrospective analysis.

Clinics (Sao Paulo) 2020 22;75:e1594. Epub 2020 Jun 22.

Department of Doppler Ultrasonil, Xingtai People's Hospital, Xingtai, Hebei, China, 054001.

Objective: Fine-needle aspiration cytology is the risk stratification tool for thyroid nodules, and ultrasound elastography is not routinely used for the differential diagnosis of thyroid cancer. The current study aimed to compare the diagnostic parameters of ultrasound elastography and fine-needle aspiration cytology, using surgical pathology as the reference standard.

Methods: In total, 205 patients with abnormal thyroid function test results underwent ultrasound-guided fine-needle aspiration cytology on the basis of the American College of Radiology Thyroid Imaging-Reporting and Data System classification and strain ultrasound elastography according to the ASTERIA criteria. Read More

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http://dx.doi.org/10.6061/clinics/2020/e1594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297517PMC

Five-year results of radiofrequency and laser ablation of benign thyroid nodules: a multicenter study from the Italian minimally-invasive treatments of the thyroid group.

Thyroid 2020 Jun 24. Epub 2020 Jun 24.

Divisione di Radiologia Interventistica, IEO, IRCCS Istituto Europeo di Oncologia, Milano, Italy, MIlan, MI, Italy.

Background: Radiofrequency and laser ablation (RFA and LA) are effective treatments for benign thyroid nodules. Due to their relatively recent introduction into clinical practice, there are limited long-term follow-up studies. This study aimed to evaluate technique efficacy, rate of regrowth and retreatment over 5 years following RFA or LA and to identify predictive factors of outcome. Read More

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http://dx.doi.org/10.1089/thy.2020.0202DOI Listing

Clinicopathologic factors and preoperative ultrasonographic characteristics for predicting central lymph node metastasis in papillary thyroid microcarcinoma: a single center retrospective study.

Braz J Otorhinolaryngol 2020 Jun 4. Epub 2020 Jun 4.

Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Department of Medical Imaging, Liaoning Province, People's Republic of China. Electronic address:

Introduction: The treatment of papillary thyroid microcarcinoma remains controversial. Central lymph node metastasis is common in papillary thyroid microcarcinoma and it is an important consideration in treatment strategy selection.

Objective: The aim of this study was to investigate clinicopathologic risk factors and thyroid nodule sonographic characteristics for central lymph node metastasis in papillary thyroid microcarcinoma. Read More

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http://dx.doi.org/10.1016/j.bjorl.2020.05.004DOI Listing

Papillary and Follicular Thyroid Cancer in children and adolescents: Current approach and future directions.

Authors:
Andrew J Bauer

Semin Pediatr Surg 2020 Jun 16;29(3):150920. Epub 2020 May 16.

The Thyroid Center, Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, 3500 Civic Center Boulevard, Buerger Center, 12-149, Philadelphia, PA USA 19104; Department of Pediatrics, The Perelman School of Medicine, The University of Pennsylvania, 415 Curie Blvd, Philadelphia, PA USA 19104. Electronic address:

An increasing number of children are diagnosed with differentiated thyroid cancer. With an excellent prognosis for the majority of pediatric patients, the goal of therapy is to optimize outcome while reducing complications. Increased knowledge of the somatic, oncogenic driver mutations provides opportunities to improve the accuracy of diagnosis, to stratify surgery, and to treat patients with morbidly invasive or refractory disease. Read More

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http://dx.doi.org/10.1016/j.sempedsurg.2020.150920DOI Listing

A pain in the neck: Salmonella spp. as an unusual cause of a thyroid abscess. A case report and review of the literature.

BMC Infect Dis 2020 Jun 22;20(1):436. Epub 2020 Jun 22.

Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Dalhousie University, 5850 University Avenue, Halifax, NS, B3K 6R8, Canada.

Background: Thyroid gland infections are rare. Their incidence is estimated to be less than 1% in immunocompromised hosts. Most common pathogens isolated are Gram positive aerobic cocci. Read More

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http://dx.doi.org/10.1186/s12879-020-05161-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310241PMC

Intuitionistic based segmentation of thyroid nodules in ultrasound images.

Comput Biol Med 2020 Jun 4;121:103776. Epub 2020 May 4.

Department of Computer Science, University of Illinois at Springfield, Springfield, IL, USA. Electronic address:

Accurate delineation of thyroid nodules in ultrasound images is vital for computer-aided diagnosis. Most segmentation methods are semi-automated for thyroid nodules and require manual intervention, which increases the processing time and errors. We propose an automated intuitionistic fuzzy active contour method (IFACM) that integrates intuitionistic fuzzy clustering with an active contour for thyroid nodule segmentation using ultrasound images. Read More

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http://dx.doi.org/10.1016/j.compbiomed.2020.103776DOI Listing

Thyroid metastases from colorectal cancer 14 years later: A case report and literature review.

Cir Cir 2020 ;88(4):508-510

Servicio de Cirugía General y del Aparato Digestivo, Hospital Clínico San Carlos, Madrid, España.

Metastases to the thyroid gland are unusual, especially from a colorectal cancer. We present the case of an 85-year-old female with a history of colon cancer in 2004 treated with surgery, who 14 years later develop dysphonia and dysphagia associated to an elevation of carcinoembryonic antigen. A pathologic thyroid mass was evidenced in a positron emission tomography-computed tomography. Read More

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http://dx.doi.org/10.24875/CIRU.19001130DOI Listing
January 2020

Lenvatininb as Treatment for Naïve Patients with Aggressive Thyroid Cancer Bone Metastases and Bad Performance Status.

Case Rep Oncol Med 2020 4;2020:8679149. Epub 2020 Jun 4.

Medical Oncology Department, Hospital Nuestra Señora de Valme, Seville, Spain.

Lenvatinib is an oral multityrosine kinase inhibitor (TKI) with proven effectiveness in the treatment of radioactive iodine- (RAI-) refractory and/or unresectable differentiated thyroid carcinoma (DTC). The present study reports the case of a 41-year-old male who underwent hemithyroidectomy in June 2015 due to a thyroid nodule with fine-needle aspiration follicular neoplasm cytology and no evidence of malignancy in the histopathological exam. Three years later, acute disabling clinical symptoms emerged, mainly high skeletal pain conditioned with an important performance status decrease. Read More

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http://dx.doi.org/10.1155/2020/8679149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292976PMC

Treatment of benign thyroid nodules by radiofrequency thermal ablation

Orv Hetil 2020 07;161(27):1131-1136

Általános Orvostudományi Kar, Transzplantációs és Sebészeti Klinika,Semmelweis Egyetem, Budapest, Baross u. 23-25., 1082.

Introduction: Benign thyroid nodules are frequent findings in imaging studies, most of the time not requiring any intervention. Treatment is usually started when nodules increase in size, the patient becomes symptomatic or clinically relevant hyperthyroidism develops. Thermoablation is an effective alternative modality. Read More

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http://dx.doi.org/10.1556/650.2020.31726DOI Listing

Liver metastasis from papillary thyroid carcinoma treated by laparoscopic hepatectomy 43 years after resection of the primary tumor: a case report.

Surg Case Rep 2020 Jun 18;6(1):142. Epub 2020 Jun 18.

Division of Hepatobiliary and Pancreatic Surgery, Integrative Center of General Surgery, Gunma University Hospital, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Background: Papillary thyroid carcinoma (PTC) generally has a good prognosis, while liver metastasis from PTC is rare and difficult to diagnose.

Case Presentation: A 67-year-old woman was diagnosed with PTC and underwent a left hemithyroidectomy 43 years ago. Two years ago, thoracoscopic right middle lobectomy was performed for a lung tumor, and pathology reports confirmed a metastatic lung tumor of PTC. Read More

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http://dx.doi.org/10.1186/s40792-020-00906-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303250PMC

Case report: exceptionally rapid growth character of hobnail variant of papillary thyroid carcinoma: a report of four cases.

Endocr J 2020 Jun 18. Epub 2020 Jun 18.

Department of Surgery, Kuma Hospital, Kobe 650-0011, Japan.

The newest WHO classification adopts hobnail variant as an aggressive variant of papillary thyroid carcinoma (PTC). We here report four cases (ages 70-76 years, all females) with hobnail variant PTC treated at Kuma Hospital. Their lesions were cytologically diagnosed as PTC before surgery, but not as hobnail variant. Read More

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http://dx.doi.org/10.1507/endocrj.EJ20-0248DOI Listing

Usage and Diagnostic Yield of Fine-Needle Aspiration Cytology and Core Needle Biopsy in Thyroid Nodules: A Systematic Review and Meta-Analysis of Literature Published by Korean Authors.

Authors:
Soon-Hyun Ahn

Clin Exp Otorhinolaryngol 2020 Jun 20. Epub 2020 Jun 20.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Objectives: The usefulness of core needle biopsy (CNB) for the diagnosis of thyroid nodules remains controversial, and preferences vary across hospitals. The purpose of this study was to assess the actual use of CNB in Korea and to analyze the advantages and disadvantages of CNB through a systematic review and meta-analysis of papers published by Korean authors.

Methods: A meta-analysis of full-text publications published in English presenting data from Korea retrieved from the Embase literature database was performed. Read More

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http://dx.doi.org/10.21053/ceo.2020.00199DOI Listing

A Combination of circRNAs as a Diagnostic Tool for Discrimination of Papillary Thyroid Cancer.

Onco Targets Ther 2020 19;13:4365-4372. Epub 2020 May 19.

Department of Endocrinology, Hefei Hospital Affiliated to Anhui Medical University, The Second People's Hospital of Hefei, Hefei 230011, People's Republic of China.

Background And Aim: Circular RNAs (circRNAs) have been highlighted to exert essential biological functions in papillary thyroid cancer (PTC). The purpose of this study was explore diagnostic utility of circRNAs in PTC patients.

Patients And Methods: The distinctive expression profile of serum circRNAs was determined by individual quantitative real-time PCR (qRT-PCR) in two independent cohorts of 113 PTC patients, 80 thyroid nodules, and 111 healthy controls (HCs). Read More

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http://dx.doi.org/10.2147/OTT.S247796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245466PMC

Performance of EU-TIRADS in malignancy risk stratification of thyroid nodules. A meta-analysis.

Eur J Endocrinol 2020 Jun 1. Epub 2020 Jun 1.

P Trimboli, Clinic for Nuclear Medicine and Competence Center for Thyroid Diseases, Imaging Institute of Southern Switzerland, Repubblica e Cantone Ticino Ente Ospedaliero Cantonale, Bellinzona, Switzerland.

Objective: Several thyroid imaging reporting and data systems (TIRADS) have been proposed to stratify the malignancy risk of thyroid nodule by ultrasound. The TIRADS by the European Thyroid Association, namely EU-TIRADS, was the last one to be published.

Design: We conducted a meta-analysis to assess the prevalence of malignancy in each EU-TIRADS class and the performance of EU-TIRADS class 5 versus 2, 3 and 4 in detecting malignant lesions. Read More

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http://dx.doi.org/10.1530/EJE-20-0204DOI Listing

Post-thyroidectomy tracheocutaneous fistula; A case report with literature review.

Int J Surg Case Rep 2020 May 30;72:172-174. Epub 2020 May 30.

Kscien Organization for Scientific Research, Hamdi Street, Sulaimani, Kurdistan, Iraq.

Introduction: Total thyroidectomy represents one of the commonest procedures performed for thyroid diseases. The aim of this paper is to report a rare case of tracheocutaneous fistula after total thyroidectomy.

Case Report: A 44-year-age female presented with left side neck swelling for 2 month duration. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.05.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299899PMC

Recurrent Laryngeal Nerve Injury After Thyroid Surgery: An Analysis of 11,370 Patients.

J Surg Res 2020 Jun 12;255:42-49. Epub 2020 Jun 12.

Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Background: Recurrent laryngeal nerve (RLN) injury is a well-known, potentially serious complication of thyroid surgery. We investigated factors associated with RLN injury during thyroid surgery using a multi-institutional data set.

Materials And Methods: Patients who underwent either lobectomy or total thyroidectomy were abstracted from the American College of Surgeons National Surgical Quality Improvement Program thyroidectomy-specific database (2016-2017). Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.017DOI Listing

Noninvasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP): Epidemiology and Long-Term Outcomes in a Strictly-Defined Cohort.

Thyroid 2020 Jun 16. Epub 2020 Jun 16.

Boston University, 1846, Surgery, 820 Harrison Avenue, FGH Building - 5th Floor, Boston, Massachusetts, United States, 02118;

A subset of encapsulated/circumscribed follicular variant of papillary thyroid carcinoma (FVPTC) was reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in 2016 to reduce overtreatment of a low-risk tumor. Study objectives were to describe the epidemiology and long-term outcomes of NIFTP in a high-volume, urban, tertiary referral center. Among patients enrolled in the Boston Medical Center (BMC) Thyroid Cancer Registry, 110 cases of FVPTC underwent index thyroid surgery at BMC, 2000-2016. Read More

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http://dx.doi.org/10.1089/thy.2019.0616DOI Listing