8,872 results match your criteria Thyroid Nodule


Management strategy for nerve damage during radiofrequency ablation of thyroid nodules.

Int J Hyperthermia 2019 Jan 14:1-7. Epub 2019 Jan 14.

a Department of Radiology and the Research Institute of Radiology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.

Objective: The aim of this study was to introduce a management strategy for nerve damage occurring during radiofrequency ablation (RFA).

Methods: From January 2016 to October 2017, 17 patients who experienced the symptoms of nerve damage during RFA were enrolled in this study. If damage to nerves was suspected during RFA, ablation was stopped immediately, and a cold solution of 5% dextrose was injected directly into the space where the nerves were located until symptoms improved. Read More

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http://dx.doi.org/10.1080/02656736.2018.1554826DOI Listing
January 2019

Oncocytic poorly differentiated (insular) thyroid carcinoma mimicking metastatic adenocarcinoma. A case report and review of the literature.

Diagn Cytopathol 2019 Jan 13. Epub 2019 Jan 13.

Department of Pathology, Hospital Universitario Dr. Peset, Valencia, Spain.

We report the cytohistologic and immunohistochemical findings of an oncocytic variant of poorly differentiated thyroid carcinoma in a 76-year old man with a prior history of prostatic adenocarcinoma. The man complained of a palpable nodule in the right thyroid lobe and cervical lymph node. Fine-needle aspiration (FNA) in both cases yielded solid clusters of cells/insulae, microfollicles, and isolated atypical cells. Read More

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http://dx.doi.org/10.1002/dc.24147DOI Listing
January 2019

Incidental pharyngoesophageal diverticulum mistaken for a thyroid nodule: Report of two cases.

Diagn Cytopathol 2019 Jan 10. Epub 2019 Jan 10.

Department of Radiology, Hsinchu MacKay Memorial Hospital, Hsinchu, Taiwan.

Pharyngeal or Zenker's diverticulum is an infrequent disorder that results from an outpouching of pharyngeal mucosa through a weakened area in the posterior pharyngeal wall. As it may mimic a thyroid nodule on ultrasonography (US), accurate diagnosis is important to ensure appropriate treatment. Fine-needle aspiration (FNA) is recommended for the initial evaluation of thyroid nodules. Read More

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http://dx.doi.org/10.1002/dc.24144DOI Listing
January 2019

A marked goiter involved in Marine-Lenhart syndrome.

J Gen Fam Med 2019 Jan 24;20(1):37-38. Epub 2018 Nov 24.

Department of General Medicine Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.

Marine-Lenhart syndrome is rare disease defined as coexistence of Graves' disease and autonomously functioning thyroid nodule. We will introduce a case of Marine-Lenhart with a huge goiter. Read More

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http://dx.doi.org/10.1002/jgf2.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321827PMC
January 2019

Is the Isthmus Location an Additional Risk Factor for Indeterminate Thyroid Nodules? Case Report and Review of the Literature.

Front Endocrinol (Lausanne) 2018 13;9:750. Epub 2018 Dec 13.

Department of Clinical Medicine and Surgery University of Naples Federico II, Naples, Italy.

The management of indeterminate thyroid lesions is controversial. The American Thyroid Association (ATA) guidelines suggest a conservative approach for low risk indeterminate thyroid lesions (TIR3A). We report a clinical case of a young girl who had TIR3A in a thyroid nodule located in the isthmus. Read More

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http://dx.doi.org/10.3389/fendo.2018.00750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315157PMC
December 2018

Non-invasive Amide Proton Transfer Imaging and ZOOM Diffusion-Weighted Imaging in Differentiating Benign and Malignant Thyroid Micronodules.

Front Endocrinol (Lausanne) 2018 12;9:747. Epub 2018 Dec 12.

Department of General Surgery, Guangdong Second Provincial General Hospital, Guangzhou, China.

Pre-operative non-invasive differentiation of benign and malignant thyroid nodules is difficult for doctors. This study aims to determine whether amide proton transfer (APT) imaging and zonally oblique multi-slice (ZOOM) diffusion-weighted imaging (DWI) can provide increased accuracy in differentiating benign and malignant thyroid nodules. This retrospective study was approved by the institutional review board and included 60 thyroid nodules in 50 patients. Read More

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http://dx.doi.org/10.3389/fendo.2018.00747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315121PMC
December 2018

CAD system based on B-mode and color Doppler sonographic features may predict if a thyroid nodule is hot or cold.

Eur Radiol 2019 Jan 9. Epub 2019 Jan 9.

Department of Radiology, Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Objectives: The aim of this study was to evaluate if the analysis of sonographic parameters could predict if a thyroid nodule was hot or cold.

Methods: Overall, 102 thyroid nodules, including 51 hyperfunctioning (hot) and 51 hypofunctioning (cold) nodules, were evaluated in this study. Twelve sonographic features (i. Read More

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http://dx.doi.org/10.1007/s00330-018-5908-yDOI Listing
January 2019

Bilateral papillitis and vitritis as the initial ophthalmologic finding in a patient with complex medical history, leading to diagnosis of multisystem sarcoidosis.

Am J Ophthalmol Case Rep 2019 Mar 21;13:122-126. Epub 2018 Dec 21.

Massachusetts Eye Research and Surgery Institution (MERSI), 1440 Main Street, Suite 201, Waltham, MA, 02451, USA.

Aim: To report a case of bilateral papillitis as the initial ophthalmologic presentation in a patient with complex medical history and multisystemic symptoms, eventually revealing a diagnosis of sarcoidosis.

Methods: Retrospective interventional case report.

Report: A 54-year-old Caucasian woman presented with bilateral decreased vision, photophobia and eye pain for a month. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183024
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http://dx.doi.org/10.1016/j.ajoc.2018.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322055PMC
March 2019
1 Read

Technical Report: A Cost-Effective, Easily Available Tofu Model for Training Residents in Ultrasound-Guided Fine Needle Thyroid Nodule Targeting Punctures.

Korean J Radiol 2019 Jan 27;20(1):166-170. Epub 2018 Dec 27.

Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China.

Objective: To establish a cost-effective and easily available phantom for training residents in ultrasound-guided fine needle thyroid nodule targeting punctures.

Materials And Methods: Tofu, drinking straws filled with coupling gel, a urine tube, and 21-gauge needles were used to generate a phantom thyroid with nodules for training. Twelve radiology residents were involved in the study. Read More

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http://dx.doi.org/10.3348/kjr.2017.0772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315077PMC
January 2019

The Role of Core Needle Biopsy for the Evaluation of Thyroid Nodules with Suspicious Ultrasound Features.

Korean J Radiol 2019 Jan 27;20(1):158-165. Epub 2018 Dec 27.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Objective: Recent studies demonstrated that core needle biopsy (CNB) can effectively reduce the possibility of inconclusive results and prevent unnecessary diagnostic surgery. However, the effectiveness of CNB in patients with suspicious thyroid nodules has not been fully evaluated. This prospective study aimed to determine the potential of CNB to assess thyroid nodules with suspicious ultrasound (US) features. Read More

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http://dx.doi.org/10.3348/kjr.2018.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315075PMC
January 2019

Can current molecular tests help in the diagnosis of indeterminate thyroid nodule FNAB?

Authors:
Carolina Ferraz

Arch Endocrinol Metab 2018 ;62(6):576-584

Unidade de Doenças da Tireoide, Divisão de Endocrinologia, Departamento de Medicina, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.

Approximately 15-30% of all thyroid nodules evaluated with fine-needle aspiration biopsy (FNAB) are classified as cytologically indeterminate. The stepwise unraveling of the molecular etiology of thyroid nodules has provided the basis for a better understanding of indeterminate samples and an opportunity to decrease diagnostic surgery in this group of patients. Over the last 15 years, several studies have tested different methodologies to detect somatic mutations (by polymerase chain reaction and next-generation sequencing, for example), and to identify differentially expressed genes or microRNA, aiming at developing molecular tests to improve the presurgical diagnosis of cytologically indeterminate nodules. Read More

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http://dx.doi.org/10.20945/2359-3997000000081DOI Listing
January 2018

Automatic thyroid nodule recognition and diagnosis in ultrasound imaging with the YOLOv2 neural network.

World J Surg Oncol 2019 Jan 8;17(1):12. Epub 2019 Jan 8.

Department of Gastrointestinal Surgery, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Street, Qingdao, 266555, Shandong Province, China.

Background: In this study, images of 2450 benign thyroid nodules and 2557 malignant thyroid nodules were collected and labeled, and an automatic image recognition and diagnosis system was established by deep learning using the YOLOv2 neural network. The performance of the system in the diagnosis of thyroid nodules was evaluated, and the application value of artificial intelligence in clinical practice was investigated.

Methods: The ultrasound images of 276 patients were retrospectively selected. Read More

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https://wjso.biomedcentral.com/articles/10.1186/s12957-019-1
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http://dx.doi.org/10.1186/s12957-019-1558-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325802PMC
January 2019
6 Reads

Treatment of solitary thyroid nodules according to size, preoperative fine-needle aspiration cytology and frozen section: a retrospective single centre study.

Acta Chir Belg 2019 Jan 7:1-9. Epub 2019 Jan 7.

a Department of Thoracic Surgery , Erasme University Hospital , Brussels , Belgium.

Background: In order to avoid unnecessary thyroidectomies, it is important to predict the nature of thyroid nodules the more accurately possible. The size of the nodule as a predictive factor for malignancy is very controversial. Another point of debate is the accuracy of preoperative fine-needle aspiration cytology (FNAC) and frozen section (FS). Read More

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http://dx.doi.org/10.1080/00015458.2018.1527566DOI Listing
January 2019

Risk stratification of the thyroid nodule with Bethesda indeterminate cytology, category III, IV, V on the one surgeon-performed US-guided fine-needle aspiration with 27-gauge needle, verified by histopathology of thyroidectomy: the additional value of one surgeon-performed elastography.

Acta Chir Belg 2019 Jan 4:1-9. Epub 2019 Jan 4.

d Department of General and Endocrine Surgery , OLV Ziekenhuis Aalst , Aalst , Belgium.

Background: The aim is to assess the value of strain elastography (SE) in differentiating likelihood of malignancy for the thyroid nodules, possessing the Bethesda Category III, IV, and V indeterminate cytology.

Methods: The data was obtained by ultrasonography (US)-guided fine-needle aspiration (US-g-FNA) via 27-gauge needle, with the verification of indicated thyroidectomies in a retrospective analysis, from April 2010 to April 2014, by enrolling the documents of 262 consecutive patients, with 327 thyroid nodules, subjected to one-surgeon performed neck US, SE, and US-g-FNA with 27-G needle to rule out the malignancy.

Results: 122 of 327 cases were Bethesda Category III, IV, and V with histopathologically benign, 110 (90. Read More

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http://dx.doi.org/10.1080/00015458.2018.1551769DOI Listing
January 2019

[Experiencia en el diagnóstico y tratamiento de 38 casos de cáncer de tiroides en población pediátrica].

Cir Cir 2019 ;87(1):7-11

Departamento de Cirugía Pediátrica, Instituto Nacional de Cancerología. Bogotá, Colombia.

Objective: To present our experience treating 38 patients with pediatric thyroid carcinoma.

Method: We received 44 pediatric patients with thyroid cancer between 2008 and 2016 in a specialized cancer center. A team of two surgeons treated all patients. Read More

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http://dx.doi.org/10.24875/CIRU.18000044DOI Listing
January 2019

Processing the entire capsule in thyroid follicular lesions improves diagnostic accuracy.

Ann Diagn Pathol 2018 Dec 23;39:21-24. Epub 2018 Dec 23.

St. John Hospital and Medical Center, Detroit, MI, USA.

Background: There is contradictory evidence in literature with respect to diagnosis and management of follicular lesions of the thyroid gland. From surgical pathology stand point, pathologists require submission and processing of entire capsule for microscopic evaluation. This can be extremely challenging especially in larger lesions. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2018.12.007DOI Listing
December 2018

Role of Metformin in the Treatment of Patients with Thyroid Nodules and Insulin Resistance: A Systematic Review and Meta- Analysis.

Thyroid 2018 Dec 29. Epub 2018 Dec 29.

Jiangsu Province Geriatric Institute, Jiangsu Province Official Hospital, Department of Endocrinology, Nanjing, Jiangsu, China ;

Background: Metformin is the most-prescribed oral medication to lower blood glucose worldwide. Some data suggest that metformin may have a role in the treatment of patients with thyroid nodules, but contrasting results are reported in different settings. This study explores and critically re-evaluates the knowledge on this topic. Read More

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http://dx.doi.org/10.1089/thy.2017.0707DOI Listing
December 2018

Predictive significance of serum dipeptidyl peptidase-IV in papillary thyroid carcinoma.

Cancer Biomark 2018 Dec 14. Epub 2018 Dec 14.

Department of Thyroid Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, China.

Background: The significance of serum dipeptidyl peptidase-IV (DPP-IV) in papillary thyroid carcinoma (PTC) has not been elucidated.

Objective: This study aimed to assess the role of serum DPP-IV in the carcinogenesis and prognosis of PTC.

Methods: The serum DPP-IV concentration was measured in 171 male patients with PTC, 81 male patients with a benign thyroid nodule (BTN), and 52 male healthy controls (HCs). Read More

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http://dx.doi.org/10.3233/CBM-170908DOI Listing
December 2018
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Ultrasound risk evaluation of thyroid nodules that are "unspecified" in the 2015 American Thyroid Association management guidelines: A retrospective study.

Medicine (Baltimore) 2018 Dec;97(52):e13914

Department of Ultrasound, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, Beijing, China.

This study sought to assess the malignant risks of "unspecified" thyroid nodules; that is, nodules that were not of a type described in the 2015 American Thyroid Association (ATA) guidelines.We retrospectively reviewed medical records and ultrasound (US) data for 1808 consecutive patients with 2614 thyroid nodules who underwent thyroidectomy between January 2015 and December 2015. Nodules with US features that did not satisfy the criteria for any risk category in the 2015 ATA guidelines were defined as "unspecified" nodules. Read More

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http://dx.doi.org/10.1097/MD.0000000000013914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314728PMC
December 2018
2 Reads

Evaluation of 167 Gene Expression Classifier (GEC) and ThyroSeq v2 Diagnostic Accuracy in the Preoperative Assessment of Indeterminate Thyroid Nodules: Bivariate/HROC Meta-analysis.

Endocr Pathol 2018 Dec 27. Epub 2018 Dec 27.

Department of Endocrinology, Metabolism and Internal Medicine, Poznań University of Medical Sciences, 49, Przybyszewskiego Street, 60-355, Poznan, Poland.

The objective of this meta-analysis was to evaluate the performance of the Gene Expression Classifier (GEC) and ThyroSeq v2 (ThyroSeq) in the preoperative diagnosis of thyroid nodules with indeterminate fine-needle aspiration biopsy results. We searched literature databases from January 2001 to April 2018. The bivariate model analysis was performed to estimate pooled sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR-), positive predictive value (PPV), and negative predictive value (NPV). Read More

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http://dx.doi.org/10.1007/s12022-018-9560-5DOI Listing
December 2018
1.644 Impact Factor

Assessment of the relationship between clinical and histopathological features in cases of thyroidectomy.

Ann Ital Chir 2018 ;89:199-205

Aim: The aim of this study is to evaluate the relationship between clinical parameters and ultimate histopathologic features of patients underwent thyroid surgery.

Method: Demographic and clinicopathologic parameters of patients who underwent thyroid surgery for benign or malignant disease in our clinic between June 2006 and March 2014 were retrospectively reviewed. Pearson's Chi-Square, Independent Sample T test, ROC Curve and Youden J Index were used to investigate whether there was any relationship between the clinical parameters and permanent histopathologic features of patients. Read More

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January 2018

Remote-Access Thyroidectomy: A Multi-institutional North American Experience with Transaxillary, Robotic Facelift, and Transoral Endoscopic Vestibular Approach.

J Am Coll Surg 2018 Dec 23. Epub 2018 Dec 23.

Division of Endocrine Surgery, Department of Surgery, Tulane University Medical Center, New Orleans, LA.

Background: Many remote-access approaches (RAA) to the thyroid have been described to circumvent anterior neck scarring, including the transaxillary (TA), robotic-facelift (RF), and transoral endoscopic vestibular approaches (TOETVA). These techniques have been popularized in Asia, but adoption has been slow in North America. We aim to examine multi-institutional North American outcomes with RAA thyroidectomy in the context of these institutions' transcervical approach (TCA) outcomes. Read More

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http://dx.doi.org/10.1016/j.jamcollsurg.2018.12.005DOI Listing
December 2018

Does hemithyroidectomy still provide any benefit?

Ann Endocrinol (Paris) 2018 Sep 25. Epub 2018 Sep 25.

Service de chirurgie viscérale et endocrinienne, CHU d'Angers, 4, rue Larrey, 49100 Angers, France.

Objectives: Multinodular goiter is a common disorder, found in 5% of the general population. If only one thyroid lobe is affected, hemithyroidectomy may be preferred to total thyroidectomy, to limit the risk of complications and avoid hormone replacement therapy, but incurs a risk of subsequent completion thyroidectomy. The aim of the present study is to determine whether the arguments in favor of hemithyroidectomy are justified and whether it still provides real benefit. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00034266183125
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http://dx.doi.org/10.1016/j.ando.2018.09.006DOI Listing
September 2018
4 Reads

Is Frozen Section Analysis During Thyroid Surgery Useful in the Era of Molecular Testing?

J Am Coll Surg 2018 Dec 21. Epub 2018 Dec 21.

Department of Surgery, University of Alabama at Birmingham, Birmingham, AL; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL. Electronic address:

Background: With the increased use of molecular testing of thyroid fine-needle biopsies, the frequency and extent of thyroid resection for thyroid nodules has changed. While the role of frozen section analysis of the thyroid has been reduced markedly in recent years, many surgeons still routinely utilize this intraoperatively. We sought to determine the utility of frozen section during thyroidectomy in the era of molecular testing. Read More

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http://dx.doi.org/10.1016/j.jamcollsurg.2018.12.002DOI Listing
December 2018

Granular cell tumor of the lung.

Diagn Cytopathol 2018 Dec 23. Epub 2018 Dec 23.

Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

A 46-year-old female with history of asthma, active smoking (20 pack-years), and schizophrenia was evaluated for a persistent asymptomatic pulmonary nodule. Her past medical history was notable for hypertension, obesity, polycystic ovary syndrome, abnormal uterine bleeding, multinodular thyroid gland, and vitamin D deficiency. Seven months before presentation, a chest radiograph (CXR) was obtained to evaluate unintended weight loss, and showed a 3 cm spiculated mass in the left lower lobe concerning for a primary lung malignancy. Read More

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http://dx.doi.org/10.1002/dc.24112DOI Listing
December 2018
2 Reads

An Unusual Case of Medullary Thyroid Carcinoma and a revision of current literature.

Endocr Metab Immune Disord Drug Targets 2018 Dec 20. Epub 2018 Dec 20.

University-Hospital "Santa Maria della Misericordia", Udine, Endocrinology and Metabolism Unit Udine. Italy.

Background: Medullary thyroid cancer (MTC) accounts for 5% of all thyroid cancers and occurs either sporadically or in a hereditary pattern. Routine calcitonin (CT) measurement is suggested for MTC screening in patients with nodular thyroid disease. Patient Findings A 45 years-old woman incidentally discovered, with neck ultrasound, the presence of thyroid micronodules. Read More

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http://dx.doi.org/10.2174/1871530319666181220165350DOI Listing
December 2018
1 Read

Correlation analyses of thyroid-stimulating hormone and thyroid autoantibodies with differentiated thyroid cancer.

J BUON 2018 Sep-Oct;23(5):1467-1471

Department of Nuclear Medicine, Affiliated Hospital, Beihua University, Jilin, China.

Purpose: To investigate the feasibilities and clinical values of thyroid-stimulating hormone (TSH) and thyroid autoantibodies in predicting differentiated thyroid cancer (DTC).

Methods: 500 patients with thyroid nodules who underwent surgery for the first time in our hospital from January 2014 to December 2016 were selected, including 250 patients definitely diagnosed pathologically with DTC and 250 patients definitely diagnosed with benign thyroid nodules after operation. Serum thyroglobulin antibody (TgAb), thyroid peroxidase antibody (TPOAb) and TSH levels before operation were evaluated in both groups. Read More

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December 2018

Successful radiofrequency ablation strategies for benign thyroid nodules.

Endocrine 2018 Dec 19. Epub 2018 Dec 19.

Department of Otolaryngology - Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Purpose: This study aimed to evaluate the effectiveness of ultrasound (US)-guided radiofrequency ablation (RFA) treatment of benign thyroid nodules in consecutive large number series. To find out whether there is any difference according to the nature of the nodules, nodules were subdivided into two groups of predominantly solid vs. predominantly cystic lesions. Read More

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http://dx.doi.org/10.1007/s12020-018-1829-4DOI Listing
December 2018

Didactic surgical experience of thyroid metastasis from renal cell carcinoma: A case report.

World J Clin Cases 2018 Dec;6(15):1018-1023

Department of Otolaryngology Head and Neck Surgery, Saga University Faculty of Medicine, Saga 849-8501, Japan.

Background: The optimal therapeutic strategy in treating thyroid metastasis from renal cell carcinoma (RCC) has not been clearly established. Here we describe a case of didactic surgical experience of the disease which caused massive intraoperative bleeding.

Case Summary: A 59-year-old male patient presented with a thyroid left lobe soft mass detected by chest computed tomography scans prior to the surgical treatment of RCC of the left kidney. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i15.1018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288516PMC
December 2018
1 Read

Killian-Jamieson diverticulum mimicking a suspicious thyroid lesion.

Clin Case Rep 2018 Dec 31;6(12):2509-2510. Epub 2018 Oct 31.

Department of Radiology Hospital Prof. Doutor Fernando Fonseca Amadora Portugal.

Killian-Jamieson diverticulum represents a rare form of esophageal diverticulum originating on the anterolateral wall of the cervical esophagus. Despite its rarity, it is crucial to recognize this entity, with such specific imaging findings, to avoid unnecessary invasive procedures such as fine-needle aspiration or even surgery. Read More

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http://dx.doi.org/10.1002/ccr3.1833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293139PMC
December 2018

A new case of Marine-Lenhart syndrome with a papillary thyroid carcinoma.

Clin Case Rep 2018 Dec 18;6(12):2299-2302. Epub 2018 Oct 18.

Department of Clinical and Experimental Medicine Endocrine Unit University of Pisa Pisa Italy.

We report the case of a patient with the coexistence of Graves' disease and autonomously functioning thyroid nodules. Because of the suspicious ultrasound pattern, he was submitted to fine-needle aspiration of the hot nodule and cytology revealed a papillary thyroid cancer. After total thyroidectomy a papillary thyroid cancer was found. Read More

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http://dx.doi.org/10.1002/ccr3.1769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293153PMC
December 2018
1 Read

Fine-needle aspiration biopsies of thyroid nodules.

Nuklearmedizin 2018 Dec 18;57(6):211-215. Epub 2018 Dec 18.

Objective: The purpose of the study was the characterization of adverse events (AEs) after fine-needle aspiration biopsies (FNABs) of thyroid nodules, as well as possible predisposing factors.

Methods: A total of 205 patients, each of whom had undergone an FNAB of a thyroid nodule, were included in the study (15 of whom were taking anticoagulant medication). The thyroid nodules were classified according to the ultrasound criteria of the American Thyroid Association (ATA). Read More

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http://dx.doi.org/10.3413/Nukmed-0981-18-06DOI Listing
December 2018
1 Read

Dual-energy CT iodine quantification for characterizing focal thyroid lesions.

Head Neck 2018 Dec 18. Epub 2018 Dec 18.

Department of Biostatistics, Korea University College of Medicine, Seoul, Republic of Korea.

Background: To determine the usefulness of dual-energy CT (DECT) iodine quantification to classify the focal thyroid lesions.

Methods: We retrospectively enrolled a total of 76 cytopathologically confirmed focal thyroid lesions (mean size: 1.9 cm). Read More

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http://doi.wiley.com/10.1002/hed.25524
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http://dx.doi.org/10.1002/hed.25524DOI Listing
December 2018
4 Reads

Retrosternal Goiter: A couple of classification methods with computed tomograpy findings.

Pak J Med Sci 2018 Nov-Dec;34(6):1494-1497

Dr. Pinar Celtikci, Department of Radiology, Kars Harakani State Hospital, Kars, Turkey.

Objectives: The retrosternal goiter (RSG), which can be defined by different classification and its incidence between 2% and 26% of all thyroidectomized patients, is a thyroid gland disease. Our aim was to classify RSG cases with a couple of different ways, which we have detected in computed tomography (CT) imaging of the thorax.

Methods: In this retrospective study conducted at Kars Harakani State Hospital Pulmonary Medicine Polyclinic between June 2014 and June 2017 in which 176 patients were included. Read More

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http://dx.doi.org/10.12669/pjms.346.15932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290211PMC
December 2018

Controversy regarding when clinically suspicious thyroid nodules should be subjected to surgery: Review of current guidelines.

Medicine (Baltimore) 2018 Dec;97(50):e13634

Background: The work-up of a thyroid nodule to diagnose malignancy is not always straightforward. There are various international thyroid societies each with their own guidelines on the approach to a thyroid nodule. The aim is therefore to determine whether a clinically suspicious thyroid nodule should be subjected to surgery. Read More

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http://dx.doi.org/10.1097/MD.0000000000013634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320209PMC
December 2018

Clinicopathologic and Molecular Features of Metastatic Follicular Thyroid Carcinoma in Patients Presenting With a Thyroid Nodule Versus a Distant Metastasis.

Am J Surg Pathol 2018 Dec 14. Epub 2018 Dec 14.

Department of Pathology, University of Chicago Medical Center.

Metastatic follicular thyroid carcinoma (FTC) is rare. The aim of this study was to determine the clinical, histologic, and molecular differences between patients with metastatic FTC who present with distant metastatic (DM) disease versus those who present with a primary thyroid nodule (PT). Clinical and pathologic information was extracted from the medical record and surgical pathology report. Read More

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http://dx.doi.org/10.1097/PAS.0000000000001208DOI Listing
December 2018

Clinical analysis of false-negative fine needle aspiration cytology of head and neck cancers.

Postgrad Med 2018 Dec 17:1-5. Epub 2018 Dec 17.

a Department of Otorhinolaryngology/Head & Neck Surgery , Hamamatsu University School of Medicine , Hamamatsu , Japan.

Background: Fine-needle aspiration (FNA) cytology is frequently used for initial and/or preoperative diagnosis of tumors in the head and neck region. However, false-negative results can lead to misdiagnosis. The aim of this study was to investigate the diagnostic results of FNA in the head and neck region and the reasons for false-negative cases. Read More

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https://www.tandfonline.com/doi/full/10.1080/00325481.2019.1
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http://dx.doi.org/10.1080/00325481.2019.1559431DOI Listing
December 2018
1 Read

High intensity focused ultrasound (HIFU) ablation of benign thyroid nodule is safe and efficacious in patients who continue taking an anti-coagulation or anti-platelet agent in the treatment period.

Int J Hyperthermia 2018 Dec 16:1-5. Epub 2018 Dec 16.

c Department of Radiology , The University of Hong Kong , Hong Kong , China.

Background: High intensity focused ultrasound (HIFU) ablation is a promising treatment for benign thyroid nodules but because bleeding complications can occur following any intervention to the thyroid gland, the safety and efficacy of HIFU ablation were evaluated in patients who continued taking an anti-coagulation or anti-platelet agent during treatment.

Methods: From 2015 to 2017, 303 patients who underwent a single-session ablation for a benign thyroid nodule were analyzed. The primary study endpoint was thyroid bleeding, intra-lesional or peri-thyroidal hematoma or neck bruising diagnosed within 4 days of the treatment. Read More

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http://dx.doi.org/10.1080/02656736.2018.1548034DOI Listing
December 2018

Quality of life and outcomes in patients with a large toxic adenoma undergoing laser ablation plus radioiodine vs lobectomy.

Int J Hyperthermia 2018 Dec 16:1-5. Epub 2018 Dec 16.

a Division of Endocrinology , "V. Fazzi" Hospital, Piazza F. Muratore , Lecce , Italy.

Purpose: Patients with toxic adenomas (TAs) that are too large to undergo radioactive iodine (RAI) treatment aimed at resolving hyperthyroidism and/or relieving mechanical pressure symptoms are referred to surgery. This prospective study aimed to assess the outcomes of combining laser ablation (LA) plus RAI vs lobectomy to treat large TAs in terms of clinical efficacy and the health-related quality of life (HRQoL).

Patients And Methods: Patients with TAs of volumes greater than 20 mL and a calculated therapeutic activity exceeding 600 Mbq were randomly assigned to undergo LA + RAI (Group A) or lobectomy (Group B). Read More

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http://dx.doi.org/10.1080/02656736.2018.1549335DOI Listing
December 2018

[A misleading breast metastasis of medullary thyroid carcinoma].

Ann Pathol 2018 Dec 12. Epub 2018 Dec 12.

Université Paris Diderot, Sorbonne-Paris-Cité, 10, avenue de Verdun, 75010 Paris, France; Service d'anatomie et cytologie pathologiques, CHU Saint-Louis, AP-HP, Paris, France.

Recognition of mammary metastases by pathologists is fundamental because their prognosis and treatment are different from those of primary mammary carcinomas. We report the case of a 54-year-old woman presenting on her mammography a left breast nodule known for 5 years, having discreetly increased in size. Breast ultrasound showed a regular 1. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02426498183011
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http://dx.doi.org/10.1016/j.annpat.2018.07.004DOI Listing
December 2018
2 Reads

[Diagnostic value of ultrasonic elastic strain ratio and elasticity score for thyroid micronodules of TI-RADS 4].

Authors:
Y Gao X Q Li S R Wang

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1795-1797

Department of Ultrasound, Yantai Affiliated Hospital of Binzhou Medical University.

To investigate diagnostic value of ultrasonic elastic strain ratio and elasticity score for thyroid micronodules of TI-RADS 4. In total, 211 consecutive patients with 225 thyroid micronodules were enroled in the study, all the nodules were evaluated by TI-RADS criteria before and all of them were examined by elastic imaging. We set the histology as the reference standard. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.007DOI Listing
December 2018

[The role of SWE and ATA(2015) guidelines combined mode in differentiation malignant from benign of Bethesda Ⅲ thyroid nodules].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1400-1405

Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Hebei North University.

To evaluate the diagnostic value of the ATA (2015) ultrasound model, shear wave elastography (SWE), and ATA (2015)+SWE combinative modality for the diagnostic efficiency in thyroid nodules with Bethesda Classification Ⅲ indeterminate cytology, determine the diagnostic value of ultrasonography in Bethesda Classification Ⅲ indeterminate cytology.216 thyroid nodules that were initially diagnosed as AUS/FLUS by fine needle aspiration (FNA) were included in this study. The clinical data and two-dimensional ultrasonographic features were compared between the benign and malignant nodules. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.18.009DOI Listing
September 2018

Primary pulmonary meningioma: A rare case report of aspiration cytological features and immunohistochemical assessment.

Diagn Cytopathol 2018 Dec 8. Epub 2018 Dec 8.

Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.

Ectopic meningioma is a generally rare type of benign tumor that very rarely occurs in the lung. Here, we report the cytological findings of a primary pulmonary meningioma with a particular focus on immunohistochemical (IHC) assessment. A healthy 60-year-old woman visited our hospital with an asymptomatic nodule in the right lower lung lobe. Read More

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http://dx.doi.org/10.1002/dc.24126DOI Listing
December 2018

Utility of microdissected cytology smears for molecular analysis of thyroid malignancy.

Diagn Cytopathol 2018 Dec 8. Epub 2018 Dec 8.

Interpace Diagnostics Lab, New Haven, Connecticut.

Background: Molecular testing of thyroid fine-needle aspirates has demonstrated value in cases of indeterminate cytology (Bethesda categories III, IV, and V) enabling optimized individual patient management leading to better outcomes with health economic benefits. For most molecular testing modalities, including mutational panels and classifier analyses, part or all of a dedicated needle aspiration pass is required to obtain an adequate sample for testing. Our analysis, which is based on a combination approach (mutation detection and microRNA classifier status), has documented clinical validity and utility when performed on thyroid fine-needle aspirates placed directly into RNA preservative fluid. Read More

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http://dx.doi.org/10.1002/dc.24100DOI Listing
December 2018

Primary thyroid biphasic synovial sarcoma and synchronous papillary carcinoma: report of a remarkable case.

Pathologica 2018 Sep;110(2):106-110

Pathology Unit, Garbagnate Milanese Hospital, ASST Rhodense, Italy.

Synovial Sarcoma (SS) is the fourth most common soft tissue sarcoma, characterized by translocation t(X;18) (p11.2;q11.2). Read More

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September 2018
3 Reads

Thyroid incidentaloma as a "PAIN" phenomenon- does it always require surgery?

Medicine (Baltimore) 2018 Dec;97(49):e13339

First Department and Clinic of General, Gastroenterological and Endocrine Surgery.

A thyroid nodule discovered during imaging study performed due to unrelated thyroid disease is known as a thyroid incidentaloma, while positron emission tomography (PET) associated incidental neoplasm of thyroid is known as a "PAIN" phenomenon.To evaluate which patients with "PAIN" phenomenon should undergo surgery in regards to cytology results.Retrospective review of 4716 patients consecutively admitted and surgically treated in tertiary surgical center. Read More

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http://dx.doi.org/10.1097/MD.0000000000013339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310517PMC
December 2018
1 Read

The diagnostic accuracy of contrast-enhanced ultrasound for the differentiation of benign and malignant thyroid nodules: A PRISMA compliant meta-analysis.

Medicine (Baltimore) 2018 Dec;97(49):e13325

Department of General Surgery, People's Hospital of Rizhao, Rizhao, China.

Background: Contrast-enhanced ultrasound (CEUS) is a non-invasive method that has been used in the diagnosis of several diseases. Recently, CEUS has been used in the differentiation of benign and malignant thyroid nodules. However, the performance of CEUS in thyroid nodules has not been studied clearly. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812070-0002
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http://dx.doi.org/10.1097/MD.0000000000013325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310493PMC
December 2018
10 Reads

Value of Contrast-Enhanced Ultrasound and Acoustic Radiation Force Impulse Imaging for the Differential Diagnosis of Benign and Malignant Thyroid Nodules.

Front Pharmacol 2018 27;9:1363. Epub 2018 Nov 27.

Department of Pathology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.

To assess the value of contrast-enhanced ultrasound (CEUS) and acoustic radiation force impulse (ARFI) imaging for the differential diagnosis of benign and malignant thyroid nodules. CEUS was performed in eighty-eight thyroid nodules. The patterns of CEUS were analyzed, and ARFI was then performed. Read More

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http://dx.doi.org/10.3389/fphar.2018.01363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277905PMC
November 2018

Evaluation of Hot Nodules of Thyroid Gland Using Tc-99m Pertechnetate: a Novel Approach Using Quantitative Single-Photon Emission Computed Tomography/Computed Tomography.

Nucl Med Mol Imaging 2018 Dec 3;52(6):468-472. Epub 2018 Nov 3.

1Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13620 South Korea.

Planar scintigraphy using Tc-99m pertechnetate is useful for snapshot evaluation of hot thyroid nodules, which are pathologically follicular adenoma and seldom, if ever, malignant. The autonomy of the hot nodules has been demonstrated by the presence of thyroid-stimulating hormone-dependent extra-nodular thyroid tissue besides the hot nodules. Here, we present two cases of hot thyroid nodules in patients who underwent quantitative single-photon emission computed tomography/computed tomography (SPECT/CT). Read More

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http://dx.doi.org/10.1007/s13139-018-0554-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261861PMC
December 2018
1 Read