8,999 results match your criteria Thyroid Nodule


A thyroid gland with over 30 foci of papillary thyroid carcinoma with activating BRAF V600E mutation.

Endocrinol Diabetes Metab Case Rep 2019 Mar 18;2019. Epub 2019 Mar 18.

Division of Endocrinology, McGill University Health Centre, Montreal, Quebec, Canada.

Multifocal papillary thyroid carcinoma (PTC) is common and the number of tumor foci rarely exceeds ten. The mechanism of multifocal disease is debated, with the two main hypotheses consisting of either intrathyroidal metastatic spread from a single tumor or independent multicentric tumorigenesis from distinct progenitor cells. We report the case of a 46-year-old woman who underwent total thyroidectomy and left central neck lymph node dissection after fine-needle aspiration of bilateral thyroid nodules that yielded cytological findings consistent with PTC. Read More

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http://dx.doi.org/10.1530/EDM-19-0006DOI Listing

Breakdown of Autonomously Functioning Thyroid Nodule Accompanied by Acromegaly After Octreotide Treatment.

Front Endocrinol (Lausanne) 2019 1;10:131. Epub 2019 Mar 1.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Patients with acromegaly are at increased risk of developing certain tumors, including goiter and thyroid nodules, and occasionally autonomous thyroid nodules. A 53-year-old woman presented at our hospital with untreated acromegaly. She had typical physical features of acromegaly with pituitary adenoma, and thyrotoxicosis with thyroid-stimulating hormone suppression was also confirmed. Read More

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http://dx.doi.org/10.3389/fendo.2019.00131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405443PMC

Risk Stratification in Differentiated Thyroid Cancer: From Detection to Final Follow-up.

J Clin Endocrinol Metab 2019 Mar 15. Epub 2019 Mar 15.

Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

Context: Modern management of differentiated thyroid cancer requires individualized care plans which tailor the intensity of therapy and follow-up to the estimated risks of recurrence and disease-specific mortality.

Evidence Acquisition: This summary is based on the authors' knowledge and extensive clinical experience supplemented by review of published review articles, thyroid cancer management guidelines, published staging systems, and original articles identified through a PubMed search which included terms such as risk stratification, staging, clinical outcomes, and differentiated thyroid cancer.

Evidence Synthesis: In the past, risk stratification in differentiated thyroid cancer usually referred to a static estimate of disease-specific mortality that was based on a small set of clinicopathological features available within a few weeks of completing initial therapy (thyroidectomy with or without radioactive iodine). Read More

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http://dx.doi.org/10.1210/jc.2019-00177DOI Listing

Killian-Jamieson diverticulum mimicking a thyroid nodule: A case report.

J Gen Fam Med 2019 Mar 8;20(2):62-64. Epub 2018 Dec 8.

Department of Emergency Medicine Osaka Medical College Takatsuki City Osaka Japan.

Killian-Jamieson diverticulum (KJD) is a rare disease of the cervical esophagus, often misidentified as thyroid nodules on ultrasonography. We performed carotid artery ultrasonography for an asymptomatic 68-year-old man. The ultrasound showed an oval nodule with heterogeneous echogenicity surrounded by a multilayered rim in the posterior left thyroid gland. Read More

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http://doi.wiley.com/10.1002/jgf2.222
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http://dx.doi.org/10.1002/jgf2.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399583PMC
March 2019
4 Reads

Non-invasive follicular thyroid neoplasm with papillary-like nuclearfeatures (NIFTP): a review and update.

Endocrine 2019 Mar 13. Epub 2019 Mar 13.

Division of Cytopathology, Department of Pathology, The Johns-Hopkins Hospital, Baltimore, USA.

Background: The nomenclature "Non-invasive Follicular Neoplasm with Papillary-like Nuclear Features (NIFTP)" was introduced in 2016. While NIFTP differs from classic papillary thyroid carcinoma (PTC) in imaging, cytomorphology, histology, molecular profile, treatment, follow up, outcome, and behavior, it largely overlaps with follicular variant of PTC at imaging and cytomorphology. Herein, we review the literature for better understanding NIFTP, and its impact on patient care. Read More

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http://dx.doi.org/10.1007/s12020-019-01887-zDOI Listing
March 2019
1 Read

RISK OF MALIGNANCY IN THYROID CYTOLOGY: THE IMPACT OF THE RECLASSIFICATION OF NONINVASIVE FOLLICULAR THYROID NEOPLASM WITH PAPILLARY-LIKE NUCLEAR FEATURES (NIFTP).

Endocr Pract 2019 Mar 13. Epub 2019 Mar 13.

From: 1Endocrinology, Diabetes and Metabolism Department, University and Hospital Center of Coimbra, Coimbra, Portugal.

Objectives: Non-invasive encapsulated follicular variant of papillary thyroid carcinoma (NEFVPTC) was recently reclassified as non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). We aimed to compare the risk of malignancy (ROM) of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) on fine-needle aspiration cytology (FNAC), before and after the reclassification, in a large cohort of patients.

Methods: We analyzed 5. Read More

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http://dx.doi.org/10.4158/EP-2018-0423DOI Listing

Aggressive papillary thyroid carcinoma in a child with type 2 congenital generalized lipodystrophy.

Arch Endocrinol Metab 2019 Feb;63(1):79-83

Grupo Brasileiro para Estudos de Lipodistrofias Herdadas e Adquiridas (BRAZLIPO), Hospital Universitário Walter Cantídio, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brasil.

Thyroid carcinoma (TC) is rare in children, particularly in those aged < 10 years. Several studies have demonstrated a correlation between neoplasms and hyperinsulinemia and insulin resistance, which are often associated with a higher risk for and/or aggressiveness of the neoplasm. Congenital generalized lipodystrophy (CGL) with autosomal recessive inheritance is a rare disease and is characterized by the lack of adipose tissue, severe insulin resistance, and early metabolic disturbances. Read More

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http://dx.doi.org/10.20945/2359-3997000000096DOI Listing
February 2019
3 Reads

Does the Bethesda category predict aggressive features in differentiated thyroid cancer?

Arch Endocrinol Metab 2019 Feb;63(1):12-15

Serviço de Endocrinologia do Hospital Universitário da Universidade Federal do Maranhão (UFMA), São Luís, MA, Brasil.

Objective: To analyze the importance of preoperative cytology of thyroid nodules and its relationship with mortality risk, recurrence risk, dynamic stratification, and aggressive characteristics (vascular invasion, aggressive histology, incomplete tumor resection, extrathyroidal extension of the tumor, and presence of lymph node and distant metastases).

Subjects And Methods: Retrospective evaluation of 153 patients diagnosed with differentiated thyroid carcinoma (DTC) and following up at the Hospital Universitário Presidente Dutra between January 1999 and December 2016.

Results: In all, 96% of the patients were female, 79. Read More

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http://dx.doi.org/10.20945/2359-3997000000098DOI Listing
February 2019
1 Read

The Efficacy and Safety of High-Intensity Focused Ultrasound (HIFU) Therapy for Benign Thyroid Nodules-A Single Center Experience from Singapore.

World J Surg 2019 Mar 12. Epub 2019 Mar 12.

Division of Thyroid and Endocrine Surgery, University Surgical Cluster, National University Health System (NUHS), NUHS Tower Block Level 8, Singapore, 119228, Singapore.

Background: High-intensity focused ultrasound (HIFU) is a recent noninvasive technique of treating thyroid nodules. Our study aims to investigate the efficacy and safety of HIFU in treating benign thyroid nodules.

Methods: This is a retrospective analysis of consecutive patients who underwent HIFU of benign thyroid nodules at our institution from July 2017-2018. Read More

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http://link.springer.com/10.1007/s00268-019-04976-2
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http://dx.doi.org/10.1007/s00268-019-04976-2DOI Listing
March 2019
5 Reads

Concomitant paraganglioma and thyroid carcinoma: A case report.

World J Clin Cases 2019 Mar;7(5):656-662

Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.

Background: Paraganglioma/pheochromocytoma and medullary thyroid carcinoma can coexist and are often found in multiple endocrine neoplasia (MEN). However, very few cases highlight papillary thyroid carcinoma. We present herein a rare case of head and neck paraganglioma associated with papillary thyroid carcinoma. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i5.656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406204PMC
March 2019
1 Read

BRAF mutation in cytologically indeterminate thyroid nodules: after reclassification of a variant thyroid carcinoma.

Onco Targets Ther 2019 21;12:1465-1473. Epub 2019 Feb 21.

Department of Otorhinolaryngology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand,

Purpose: Fine-needle aspiration biopsy (FNAB) is regarded by the Bethesda system as the gold-standard investigation for stratifying the risk of malignancy of a thyroid nodule. However, some limitations affect the adequacy of the obtained materials, resulting in 30% of the cytological results remaining in the indeterminate category. We aimed to investigate the diagnostic value of the BRAF mutation in cytologically indeterminate thyroid nodules after the reclassification of a variant thyroid carcinoma. Read More

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http://dx.doi.org/10.2147/OTT.S190001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391130PMC
February 2019
1 Read

Thyroid Nodules are More Prevalent in Subjects with Colon Polyps, Independent of Insulin Resistance.

Med Princ Pract 2019 Mar 13. Epub 2019 Mar 13.

Objective: Colorectal polyps and thyroid nodules are common disorders linked to hyperinsulinemia and metabolic syndrome (Mets). The direct association between these two diseases is not clear. We aimed to analyze the prevalence of thyroid nodules in subjects with and without colorectal polyps. Read More

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http://dx.doi.org/10.1159/000499527DOI Listing
March 2019
1 Read

The influence of thyroid nodule size on the diagnostic efficacy and accuracy of ultrasound guided fine-needle aspiration cytology.

Diagn Cytopathol 2019 Mar 12. Epub 2019 Mar 12.

Department of Endocrinology and Metabolism, Ankara University Faculty of Medicine, Ankara, Turkey.

Background: Diagnostic accuracy of fine-needle aspiration cytology (FNAC) in large and subcentimeter nodules is still debated. We aimed to evaluate the impact of nodule size on efficacy of the ultrasound-guided FNAC.

Methods: B-mode grayscale ultrasound (US), US-guided FNAC according to Bethesda system and histopathological data of 514 nodules from 371 patients, who underwent thyroidectomy were examined retrospectively. Read More

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http://doi.wiley.com/10.1002/dc.24170
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http://dx.doi.org/10.1002/dc.24170DOI Listing
March 2019
1 Read

Long Term Efficacy of a Single Session RFA of Benign Thyroid Nodules: A Longitudinal 5-Year Observational Study.

J Clin Endocrinol Metab 2019 Mar 12. Epub 2019 Mar 12.

Endocrinology, Diabetes and Metabolism Department and "Center for Thyroid Diseases", A.O. Ordine Mauriziano, Turin, Italy.

Context: Radiofrequency ablation (RFA) of benign thyroid nodules has been gaining consensus. However, solid information on its long-term efficacy is yet to be obtained.

Objective: To analyze the long-term results of single-session RFA. Read More

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http://dx.doi.org/10.1210/jc.2018-02808DOI Listing

Transoral endoscopic thyroidectomy using vestibular approach: A single center experience.

J Postgrad Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Surgery, Seth GS Medical College, Parel, Mumbai, Maharashtra, India.

Background: Thyroid Natural Orifice Transluminal Endoscopic Surgery (NOTES) or transoral endoscopic thyroidectomy using vestibular approach is a recent advance embraced by the surgical community because of its potential for a scar-free thyroidectomy. In this article, we present our initial experience with this technique.

Materials And Methods: We used a three-port technique through the oral vestibule, one 10 mm port for the laparoscope and two additional 5 mm ports for the endoscopic instruments required. Read More

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http://dx.doi.org/10.4103/jpgm.JPGM_117_18DOI Listing
March 2019
1 Read

Ultrasound-guided fine needle aspiration of thyroid nodules with on-site cytological examination: Diagnostic efficacy, prevalence, and factors predicting for Bethesda category I results.

Endocrinol Diabetes Nutr 2019 Mar 8. Epub 2019 Mar 8.

Servicio de Otorrinolaringología, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, España.

Background And Objective: Ultrasound-guided fine needle aspiration of thyroid nodules with on-site cytological examination may decrease the number of Bethesda categoryI cytologies. The study objective was to evaluate our second-year experience with this procedure to analyze diagnostic efficacy, prevalence, and factors predicting for Bethesda categoryI results.

Patients And Method: A retrospective study was conducted of 279 nodules from 233 patients. Read More

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http://dx.doi.org/10.1016/j.endinu.2018.12.006DOI Listing

Impact of thyroid nodule sizes on the diagnostic performance of Korean thyroid imaging reporting and data system and contrast-enhanced ultrasound.

Clin Hemorheol Microcirc 2019 Mar 7. Epub 2019 Mar 7.

Department of Ultrasound, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi, China.

Objective: This study aimed to evaluate the impact of thyroid nodule sizes on the diagnostic performance of Korean thyroid imaging reporting and data system (TIRADS) and contrast-enhanced ultrasound (CEUS).

Methods: In total, 308 consecutive patients with 382 thyroid nodules underwent US-guided FNA or surgery were included in this retrospective study. The nodule size was classified into 3 categories: ≤10 mm (group A), 10-20 mm (group B), and ≥20 mm (group C). Read More

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http://dx.doi.org/10.3233/CH-180545DOI Listing

Virtual Touch Tissue Imaging and Quantification (VTIQ) combined with the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) for malignancy risk stratification of thyroid nodules.

Clin Hemorheol Microcirc 2019 Mar 2. Epub 2019 Mar 2.

In-Patient Ultrasound Department, Second Affiliated Hospital of Harbin Medical University, Nangang, Harbin, Heilongjiang prov, China.

Objective: This study was conducted to investigate the diagnostic performance of Virtual Touch Tissue Imaging and Quantification (VTIQ), combined with the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) in differentiating malignant and benign thyroid nodules.

Methods: A total of 130 thyroid nodules in 128 patients were included. The diagnostic performance of conventional ultrasound (US), VTIQ, and the combination of these two techniques was calculated and compared according to the area under the receiver operating characteristic curve (AUROC), for sensitivity, specificity, and accuracy. Read More

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/CH-180477DOI Listing
March 2019
5 Reads

First report of in-situ preservation of a subcapsular parathyroid gland through super-meticulous capsular dissection during robotic radical thyroidectomy.

Surg Oncol 2019 Mar 26;28:9-13. Epub 2018 Oct 26.

Breast and Thyroid Surgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. Electronic address:

Purpose: Meticulous capsular dissection can preserve the function of the parathyroid gland in most patients, but it is difficult to identify and preserve the subcapsular parathyroid gland. We performed in-situ preservation of the subcapsular parathyroid gland during robotic radical thyroidectomy using super-meticulous capsular dissection, and evaluated its effect on postoperative parathyroid function.

Methods: A 45-year-old woman was admitted with bilateral thyroid nodules. Read More

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http://dx.doi.org/10.1016/j.suronc.2018.10.009DOI Listing

Multispectral optoacoustic tomography of benign and malignant thyroid disorders - a pilot study.

J Nucl Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Nuclear Medicine, University Hospital Münster, Germany, Germany.

This study aims at evaluating hybrid multispectral optoacoustic tomography (MSOT)/ultrasound for imaging of thyroid disorders, including Graves' disease and thyroid nodules. The functional biomarkers and tissue parameters deoxygenated (HbR), oxygenated (HbO2) and total hemoglobin (HbT), saturation of hemoglobin (sO2), fat and water content were analyzed in thyroid lobes affected by Graves' disease ( = 6), thyroid lobes with healthy thyroid tissue ( = 8), benign ( = 13) and malignant ( = 3) thyroid nodules. In Graves' disease, significantly higher values for HbR (3. Read More

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http://dx.doi.org/10.2967/jnumed.118.222174DOI Listing
March 2019
1 Read

Multiple endocrine neoplasia type 2A syndrome (MEN2A) and usefulness of 68Ga-DOTATATE PET/CT in this syndrome.

Ann Ital Chir 2019 Mar 4;8. Epub 2019 Mar 4.

Aim: The aim of this study was to evaluate a new imaging method 68Ga-DOTATATE PET/CT as an alternative method to diagnose evidence of neuroendocrine tumors or their metastasis (if any) in patient with MEN 2A.

Methods: Three patients( 2F, 1M; age 28,46 and 50 years) with MEN 2A syndrome who underwent 68Ga-DOTATATE PET/CT scan were prospectively evaluated. PET/CT images were analyzed with measurement of maximum standardized uptake value (SUVmax). Read More

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March 2019
4 Reads

[Association of Body Mass Index and Risk Stratification of Thyroid Nodules in a Multi-center Healthy Population].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2019 Feb;41(1):93-98

Department of Ultrasound,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

Objective To investigate the relationship between body mass index(BMI)and risk levels of thyroid nodules in a multi-center healthy population. Methods A total of 6070 subjects were enrolled from five medical physical examination centers in China from January 2015 to December 2017. All the participants'general information and parameters were recorded. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.10416DOI Listing
February 2019
2 Reads

Ectopic Parathyroid Adenoma in Piriform Sinus: Case Report and Review of the Literature.

Ear Nose Throat J 2019 Jan 28;98(1):14-17. Epub 2019 Jan 28.

1 Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.

During routine blood work, a 53-year-old female patient was noted to have asymptomatic hypercalcemia and subsequently found to have hyperparathyroidism. Localization studies for a suspected parathyroid adenoma included Tc Sestamibi scintigraphy, Single Photon Emission Computed Tomography (SPECT)/computed tomography (CT) study, and ultrasound of the neck, which were initially read as negative for parathyroid adenoma. A contrast-enhanced CT scan of the neck was performed to locate the suspected parathyroid adenoma and demonstrated a soft tissue lesion within the right piriform sinus. Read More

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http://dx.doi.org/10.1177/0145561318822933DOI Listing
January 2019
2 Reads

Comparison and preliminary discussion of the reasons for the differences in diagnostic performance and unnecessary FNA biopsies between the ACR TIRADS and 2015 ATA guidelines.

Endocrine 2019 Mar 4. Epub 2019 Mar 4.

Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, 130000, Jilin, China.

Objectives: (1) To compare the American College of Radiology (ACR) thyroid imaging reporting and data system (TIRADS) and American Thyroid Association (ATA) guidelines for thyroid nodules with regard to diagnostic performance and effectiveness at reducing the number of fine-needle aspiration (FNA) biopsies and to preliminarily discuss the reasons for the differences and (2) to compare the diagnostic performance of the two guidelines in the subgroup of nodules <1 cm in diameter.

Materials And Methods: In the present study, 1000 thyroid nodules in 894 consecutive patients with final diagnoses were included; these thyroid nodules were investigated via FNA biopsies in our hospital. The ultrasound (US) features of the thyroid nodules were reviewed and stratified according to the categories defined by the ACR TIRADS and ATA guidelines. Read More

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http://dx.doi.org/10.1007/s12020-019-01886-0DOI Listing
March 2019
1 Read

Diagnostic value of multimodal ultrasound imaging in differentiating benign and malignant TI-RADS category 4 nodules.

Int J Clin Oncol 2019 Mar 1. Epub 2019 Mar 1.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.

Background: Differential diagnosis of benign and malignant thyroid imaging reporting and data system category 4 (TI-RADS-4) nodules can be difficult using conventional ultrasound (US). This study aimed to evaluate whether multimodal ultrasound imaging can improve differentiation and characterization of benign and malignant TI-RADS-4 nodules.

Methods: Multimodal ultrasound imaging, including US, superb microvascular imaging (SMI), and real-time elastography (RTE), were performed on 196 TI-RADS-4 nodules (78, benign; 118, malignant) in 170 consecutive patients. Read More

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http://dx.doi.org/10.1007/s10147-019-01397-yDOI Listing
March 2019
2 Reads

Ultrasound-guided needle biopsy of large thyroid nodules: Core needle biopsy yields more reliable results than fine needle aspiration.

J Clin Ultrasound 2019 Feb 28. Epub 2019 Feb 28.

Department of Radiology, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Republic of Korea.

Purpose: The objective of this study was to compare the false negative rate, sensitivity and false positive rate of ultrasound (US)-guided fine needle aspiration (FNA) with those of US-guided core needle biopsy (CNB) for large thyroid nodules ≥2.0 cm, which reportedly have an increased risk of thyroid malignancy.

Methods: We retrospectively studied surgically confirmed thyroid nodules that had preoperative US-guided FNA or CNB between March 2005 and December 2013. Read More

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http://dx.doi.org/10.1002/jcu.22721DOI Listing
February 2019

Fine-needle aspiration cytology of a thyroid nodule: Challenging morphologic considerations.

Cytojournal 2019 11;16. Epub 2019 Feb 11.

Address: Department of Pathology, The Ohio State University Wexner Medical Center, Chillicothe, Columbus, OH, USA.

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http://dx.doi.org/10.4103/cytojournal.cytojournal_8_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388538PMC
February 2019

A case report of a giant mature teratoma of the thyroid gland in a young girl.

Medicine (Baltimore) 2019 Mar;98(9):e14703

Rationale: Teratomas are extremely rare in the thyroid gland. A cervical teratoma presenting as a cystic or mixed thyroid lesion can be easily confused with a thyroglossal duct cyst. It is difficult for pediatricians to differentiate between these 2 types of lesions. Read More

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http://dx.doi.org/10.1097/MD.0000000000014703DOI Listing
March 2019
1 Read

Characteristics and outcomes of patients with hyperthyroidism attending a hospital endocrine clinic-A retrospective study.

Endocrinol Diabetes Metab 2019 Jan 28;2(1):e00046. Epub 2018 Nov 28.

Poole Hospital, NHS Foundation Trust Poole UK.

Aims: A study looking at the distribution, management and outcomes of patients referred to a secondary care endocrine clinic with a diagnosis of hyperthyroidism.

Methods: Retrospective longitudinal study of 442 patients referred over a 15-year period (2002-2017) with a diagnosis of hyperthyroidism to a secondary care endocrine clinic. Information on demographics, diagnosis, treatments and outcomes was recorded as patients attended for clinic visits. Read More

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http://doi.wiley.com/10.1002/edm2.46
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http://dx.doi.org/10.1002/edm2.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354748PMC
January 2019
3 Reads

Diagnostic accuracy of ultrasound and fine-needle aspiration in the study of thyroid nodule and multinodular goitre.

Endocrinol Diabetes Metab 2018 Jul 19;1(3):e00024. Epub 2018 Jun 19.

Department of General Surgery Hospital de la Santa Creu i Sant Pau Barcelona Spain.

Objective: Ultrasonography and cytology obtained by fine-needle aspiration are part of the basic study of the thyroid nodule. Although they are not diagnostic in every case, they are cost-effective methods that inform surgical treatment and its extent. The purpose of this study was to evaluate the accuracy of ultrasonography associated with fine-needle aspiration to predict malignancy in nodular thyroid pathology. Read More

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http://dx.doi.org/10.1002/edm2.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354818PMC
July 2018
1 Read

Changes in the size of the thyroid in patients with benign non-toxic multinodular goiter after radioactive iodine therapy.

Med J Islam Repub Iran 2018 27;32:131. Epub 2018 Dec 27.

Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism ,Iran University of Medical Sciences Tehran, Iran.

Multinodular goiter (MNG) is regarded as one of the most common causes of hyperthyroidism, particularly in areas of mild-to-moderate iodine deficiency. The present study aims to explore the effects of the radioactive iodine (RAI) therapy on benign non-toxic MNG and evaluate its side effects. Patients with benign non-toxic MNG entered the study. Read More

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http://dx.doi.org/10.14196/mjiri.32.131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387795PMC
December 2018
3 Reads

Validation of web-based thyroid imaging reporting and data system in atypia or follicular lesion of undetermined significance thyroid nodules.

Head Neck 2019 Feb 24. Epub 2019 Feb 24.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

Background: Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) show variable malignancy risk. We validated the web-based predictive models and the scoring system by the American College of Radiology (ACR) for AUS/FLUS nodules to stratify the malignancy risk.

Methods: From January 2011 to November 2014, 275 consecutive nodules diagnosed as AUS/FLUS were enrolled. Read More

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http://dx.doi.org/10.1002/hed.25677DOI Listing
February 2019
1 Read

Metastasis of renal cell carcinoma to the parathyroid gland 12 years after radical nephrectomy.

J Surg Case Rep 2019 Feb 19;2019(2):rjz032. Epub 2019 Feb 19.

General Surgery Department, Unidade Local de Saúde do Baixo Alentejo, Beja 7801-849, Portugal.

Renal cell carcinoma (RCC) accounts for 2-3% of all malignant tumors in adults. RCC is well-known for its propensity to metastasize to unusual sites, and late metastasis, even after several years, is common. Involvement of the parathyroid gland has only four reported cases in literature. Read More

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http://dx.doi.org/10.1093/jscr/rjz032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380075PMC
February 2019
2 Reads

Accuracy of the European Thyroid Imaging Reporting and Data System (EU-TIRADS) in the valuation of thyroid nodule malignancy in reference to the post-surgery histological results.

Pol J Radiol 2018 19;83:e579-e586. Epub 2018 Dec 19.

Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Poland.

Purpose: To assess the clinical usefulness of the European Thyroid Imaging and Reporting Data System (EU-TIRADS) in the valuation of thyroid nodules malignancy in reference to post-surgery histological results.

Material And Methods: Pre-operative ultrasound was performed in consecutive patients admitted for thyroid surgery between June 2017 and January 2018. Thyroid nodules were classified according to EU-TIRADS to five groups: 1-5. Read More

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http://dx.doi.org/10.5114/pjr.2018.81556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384399PMC
December 2018

Ectopic thyroid-stimulating hormone-secreting pituitary adenoma of the nasopharynx diagnosed by Ga-DOTA-TATE PET/CT.

World Neurosurg 2019 Feb 21. Epub 2019 Feb 21.

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of California, San Francisco.

Ectopic thyroid-secreting hormone (TSH)-secreting pituitary adenomas are rare, with only nine cases reported in the literature. We describe a case of an ectopic TSH-secreting pituitary adenoma located in the nasopharynx in a patient initially presenting with signs and symptoms of hyperthyroidism that persisted despite treatment with anti-thyroid medications. Magnetic resonance imaging (MRI) of the pituitary gland was normal, though subsequent review by neuroradiology revealed a nodule attached to the posterior septum in the nasopharynx that was, in retrospect, seen on several other MR scans. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.022DOI Listing
February 2019
1 Read

Experience of thyroid surgery at tertiary referral centers in Jazan Hospitals, Saudi Arabia.

Interv Med Appl Sci 2018 Dec;10(4):198-201

Faculty of Medicine, Department of Otorhinolaryngology-Head and Neck Surgery, Prince Mohammed bin Nasser Hospital, Jazan, Saudi Arabia.

Background: Benign multinodular goiter (BMNG) is a common disease of the thyroid gland with palpable thyroid nodules that may be detected in 0.8%-1.5% of men and 5. Read More

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http://dx.doi.org/10.1556/1646.10.2018.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376351PMC
December 2018
1 Read

Appropriate Neck Ultrasonography Surveillance During the First 10 Years After Hemithyroidectomy in Papillary Thyroid Microcarcinoma Patients: A Single-Center Study.

Ultrasound Q 2019 Feb 16. Epub 2019 Feb 16.

Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon, South Korea.

This study aimed to assess the prevalence of tumor recurrence/persistence and determine the appropriate frequency and interval of follow-up neck ultrasonography (US) in papillary thyroid microcarcinoma (PTMC) patients who underwent hemithyroidectomy and long-term follow-up US. From January 2005 to December 2006, 179 patients underwent a hemithyroidectomy for the treatment of PTMC and at least 1 postoperative US surveillances. The postoperative follow-up US was performed by 2 radiologists for all patients. Read More

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http://dx.doi.org/10.1097/RUQ.0000000000000429DOI Listing
February 2019

Thyroid Nodules Cytopathology Applying the Bethesda System with Histopathological Correlation.

Saudi J Med Med Sci 2018 Sep-Dec;6(3):143-148. Epub 2018 Aug 14.

Department of Pathology, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Jeddah, KSA.

Background: Fine-needle aspiration cytology remains a valuable screening tool for preoperative management of thyroid nodules. However, the rates of false-negative and false-positive diagnosis remain a challenge for pathologists.

Objectives: To assess the value of thyroid fine-needle aspiration as a screening tool and its accuracy of diagnoses relative to final histological diagnoses. Read More

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http://dx.doi.org/10.4103/sjmms.sjmms_178_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196689PMC

Transoral Robotic Thyroidectomy Versus Conventional Open Thyroidectomy: Comparative Analysis of Surgical Outcomes in Thyroid Malignancies.

J Laparoendosc Adv Surg Tech A 2019 Feb 20. Epub 2019 Feb 20.

5 Division for Endocrine and Minimal Invasive Surgery, Department of Human Pathology in Adulthood and Childhood "G.Barresi," University Hospital "G.Martino," University of Messina, Messina, Italy.

Background: Various approaches for thyroid surgery became possible with the use of robotic systems. Transoral robotic thyroidectomy (TORT) is one of the newest approaches and draws attention because of its cosmetic excellence. In this study, we compared the surgical outcomes of TORT and conventional open thyroidectomy (OT). Read More

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http://dx.doi.org/10.1089/lap.2018.0587DOI Listing
February 2019

Malignant peripheral nerve sheath tumor of the pancreas-A case report.

Int J Surg Case Rep 2019 13;55:239-242. Epub 2019 Feb 13.

Department of General Surgery, Department of Surgical Gastroentrology, Saveetha Medical College Hospital, India.

Introduction: Nerve sheath tumors are tumors arising from nerve sheaths or which show nerve sheath differentiation. They are divided as benign and malignant. They are associated with Von Recklinghausen syndrome. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383168PMC
February 2019
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Core-needle biopsy in thyroid nodules: performance, accuracy, and complications.

Eur Radiol 2019 Feb 19. Epub 2019 Feb 19.

University of the Basque Country (UPV/EHU), Leioa, Spain.

Objective: To evaluate the performance of core-needle biopsy (CNB) in thyroid using a cohort of patients in which it was used as first choice.

Methods: Our institutional review board approved this retrospective study. We reviewed all CNB performed in our center over a period of 11 years. Read More

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http://link.springer.com/10.1007/s00330-019-06038-6
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http://dx.doi.org/10.1007/s00330-019-06038-6DOI Listing
February 2019
7 Reads

Expression of in Circulating Tumor Cells May Distinguish Follicular Thyroid Carcinomas from Adenomas: Implications for Blood-Based Preoperative Diagnosis.

J Clin Med 2019 Feb 18;8(2). Epub 2019 Feb 18.

Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.

Preoperative diagnosis of thyroid nodules reduces unnecessary surgery. Circulating tumor cells (CTCs) may contain information of primary tumor(s). We asked whether the peripheral blood expression of genes specific for circulating tumor cells (CTCs) differentiates benign thyroid nodules from malignant nodules. Read More

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http://www.mdpi.com/2077-0383/8/2/257
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http://dx.doi.org/10.3390/jcm8020257DOI Listing
February 2019
3 Reads

Two sequential applications of high-intensity focused ultrasound (HIFU) ablation for large benign thyroid nodules.

Eur Radiol 2019 Feb 18. Epub 2019 Feb 18.

Department of Radiology, The University of Hong Kong, Hong Kong SAR, China.

Objective: High-intensity focused ultrasound (HIFU) ablation is a promising treatment for benign thyroid nodules but single application is less effective in larger-sized nodules. We aimed to assess the efficacy and safety of two sequential applications in larger-sized nodules.

Methods: Fifty patients underwent ablation of a large-sized nodule (baseline volume ≥ 20 mL and diameter ≤ 50 mm). Read More

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http://dx.doi.org/10.1007/s00330-019-06021-1DOI Listing
February 2019
1 Read

Diagnostic Performance of Practice Guidelines for Thyroid Nodules: Thyroid Nodule Size versus Biopsy Rates.

Radiology 2019 Feb 19:181723. Epub 2019 Feb 19.

From the Department of Radiology and Thyroid Center, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea (S.M.H.); Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43 gil, Songpa-gu, Seoul 05505, Korea (J.H.B., C.H.S., S.R.C., Y.J.C., J.H.L.); and Department of Radiology, GangNeung Asan Hospital, University of Ulsan College of Medicine, Seoul, Korea (D.G.N.).

Background The diagnostic performance and unnecessary biopsy rates for evaluation of thyroid nodules varies among the current society guidelines. We hypothesized that diagnostic performance and unnecessary biopsy rates of different guidelines are largely determined by different thyroid size thresholds used as cutoff values that determine when to biopsy a thyroid nodule. Purpose To compare the malignancy risk, diagnostic performance, and unnecessary biopsy rates of three guidelines and evaluate the changes according to the nodule size cutoff for biopsy. Read More

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http://dx.doi.org/10.1148/radiol.2019181723DOI Listing
February 2019

Should we perform fine needle aspiration cytology of subcentimetre thyroid nodules? A retrospective review of local practice.

Ultrasound 2019 Feb 9;27(1):64-68. Epub 2019 Jan 9.

Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore, Singapore.

In light of the rising rate of incidentally detected subcentimetre thyroid nodules due to improved surveillance and diagnostic imaging, the decision of whether to perform fine needle aspiration cytology is increasingly pertinent. We aim to assess (1) the sampling adequacy of fine needle aspiration cytology, (2) malignancy rate, (3) thyroidectomy rate and (4) diagnostic accuracy of fine needle aspiration cytology. A total of 245 subcentimetre nodules in 220 patients underwent fine needle aspiration cytology between 2011 and 2014. Read More

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http://dx.doi.org/10.1177/1742271X18820556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362542PMC
February 2019
1 Read

Preliminary report of microwave ablation for the primary papillary thyroid microcarcinoma: a large-cohort of 185 patients feasibility study.

Endocrine 2019 Feb 15. Epub 2019 Feb 15.

Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130000, China.

Purpose: To assess the safety and efficacy of microwave ablation (MWA) for primary papillary thyroid microcarcinoma (PTMC) with a large sample of 185 patients.

Methods: A total of 185 patients underwent MWA for 206 primary PTMC nodules. They received ultrasound follow-up at 1, 3, 6, and 12 months after MWA and every 6 months thereafter. Read More

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http://dx.doi.org/10.1007/s12020-019-01868-2DOI Listing
February 2019
1 Read

Prevalence of Cancer in Thyroid Nodules In the Veteran Population.

Fed Pract 2018 Aug;35(Suppl 5):S48-S51

is a Medical Resident; was a Medical Student at the time of the study; is a Professor of Medicine and Vice Chairman for Research in the Department of Internal Medicine; and is an Associate Professor of Medicine at Wright State University Boonshoft School of Medicine in Dayton, Ohio. Dr. Gupta also is Section Chief, Endocrinology at the Dayton Veterans Affairs Medical Center in Ohio.

A 16-year retrospective chart review found no relationship between nodule size and malignancy, emphasizing the need for individualized care. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248147PMC

Systematic thyroid screening in myotonic dystrophy: link between thyroid volume and insulin resistance.

Orphanet J Rare Dis 2019 02 13;14(1):42. Epub 2019 Feb 13.

CHU Lille, Endocrinology, Diabetology and Metabolism, F-59000, Lille, France.

Background: Myotonic dystrophy (DM1), a neuromuscular disease related to DMPK gene mutations, is associated to endocrine disorders and cancer. A routine endocrine work-up, including thyroid ultrasound (US), was conducted in 115 genetically-proven DM1 patients in a neuromuscular reference center. The aim of this study was to determine the prevalence and the causes of US thyroid abnormalities in DM1. Read More

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http://dx.doi.org/10.1186/s13023-019-1019-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375124PMC
February 2019
2 Reads

Patient satisfaction of radiofrequency ablation for symptomatic benign solid thyroid nodules: our experience for 2-year follow up.

BMC Cancer 2019 Feb 13;19(1):147. Epub 2019 Feb 13.

Department of Ultrasound, Beijing Tian Tan Hospital, Capital Medical University, No. 119 West Road of South 4th Ring Road, Fengtai District, Beijing, 100160, China.

Background: The patient satisfaction of symptoms improvement and disease factors that may affect long-term treatment efficacy of radiofrequency ablation (RFA) for non-functioning solid benign thyroid nodules (TNs) over a 2-year follow up study was investigated.

Methods: This retrospective study evaluated 194 non-functioning solid benign TNs of 103 patients. The TNs were categorized as small (≤5 ml), medium (5. Read More

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http://dx.doi.org/10.1186/s12885-019-5338-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375217PMC
February 2019
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The effect of disease activity on thyroid nodules in patients with acromegaly.

Endocr J 2019 Feb 9. Epub 2019 Feb 9.

Department of Endocrinology and Metabolism, Diskapi Teaching and Research Hospital, Ankara, Turkey.

Nodular thyroid disease is a very common disorder in patients with acromegaly. Insulin-like growth factor-1 (IGF-1) is a thyroid growth factor, and there is a correlation between IGF-1 levels and thyroid volume (TV) in patients with acromegaly. There is no study investigating the impact of somatostatin analog (SSA) treatment on thyroid nodule volume in patients with acromegaly. Read More

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https://www.jstage.jst.go.jp/article/endocrj/advpub/0/advpub
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http://dx.doi.org/10.1507/endocrj.EJ18-0502DOI Listing
February 2019
11 Reads