Value of cytokeratin-19, Hector Battifora mesothelial-1 and galectin-3 immunostaining in the diagnosis of thyroid neoplasms.
- Rajasekhar Sanuvada,
- Rukmangadha Nandyala,
- Amit Kumar Chowhan,
- Phaneendra Bobbidi,
- Mutheeswariah Yootla,
- Narendra Hulikal,
- Alok Sachan
J Lab Physicians 2018 Apr-Jun;10(2):200-207
Department of Endocrinology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Background: Diagnosis of types and aggressiveness of thyroid cancers is difficult. The "gold standard" in diagnosis is using routine hematoxylin and eosin staining. Several markers have been investigated for differentiating them among which cytokeratin-19 (CK-19), Hector Battifora mesothelial cell (HBME-1), and galectin-3 are found to be most commonly used. Read More