Expression of cancer/testis antigens MAGE-A, MAGE-C1, GAGE and CTAG1B in benign and malignant thyroid diseases.
- Daniel Hardy Melo,
- Rui Celso Martins Mamede,
- Luciano Neder,
- Wilson Araújo Silva,
- Mateus Camargo Barros-Filho,
- Luiz Paulo Kowalski,
- Clóvis Antonio Lopes Pinto,
- Marco Antônio Zago,
- David Livingstone Alves Figueiredo,
- Achim A Jungbluth
Oncol Lett 2017 Dec 26;14(6):6485-6496. Epub 2017 Sep 26.
Division of Pathology Diagnostic Services, Cytology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Despite considerable advances in the understanding of thyroid gland biology, correctly diagnosing thyroid nodules and treating high-grade thyroid carcinoma remains challenging. Cancer/testis (CT) antigens have emerged as potential diagnostic tools as well as targets of potential cancer vaccinations. In the present study, a total of 117 patients who underwent surgical therapy for thyroid disease were available for analysis. Read More