Radiol Cardiothorac Imaging 2021 Apr 25;3(2):e200418. Epub 2021 Mar 25.
Faculty of Medical Sciences, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras (J.A.R.); Department of Radiology, Division of Cardiopulmonary Imaging, University of Colorado School of Medicine, 12401 E 17th Ave, Aurora, CO 80045 (T.J.B., D.V.); Department of Radiology, University of Texas Health Science Center, San Antonio, Tex (C.S.R.); Department of Radiology, Weill Cornell Medicine, New York, NY (D.B.G.); and Department of Radiology, Children's Hospital Colorado, Aurora, Colo (L.P.B.).
Primary immunodeficiency disorders (PIDs), which are humoral, combined, and innate defects of the immune system, are relatively uncommon and may go undiagnosed in patients experiencing recurrent infections, resulting in increased morbidity and mortality. PIDs are clinically characterized by a broad spectrum of disorders, including repeated infections, autoimmune disorders, lymphoproliferative diseases, congenital anomalies, and increased risk of malignancy. Cardiothoracic imaging plays a crucial role in the diagnosis of PIDs owing to the high rates of repeated respiratory infections leading to bronchiectasis and other forms of chronic lung disease. Read More