209 results match your criteria Thymic Lesion Imaging


Giant cervicomediastinal thymic cyst in an elderly: diagnosis by multimodality imaging and fine-needle aspiration cytology with immunocytochemistry.

BMJ Case Rep 2020 Jul 6;13(7). Epub 2020 Jul 6.

Pulmonary Medicine, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, Odisha, India.

A 65-year-old woman, a non-smoker, presented to the pulmonary medicine outpatient department with chest pain, mild dyspnoea, right side neck swelling and mild facial puffiness. The cervical swelling was soft, non-tender and fluctuant on palpation. Multimodality imaging revealed a large, thin-walled cervicomediastinal cystic lesion with septations, haemorrhage, septal calcification and without any solid component. Read More

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http://dx.doi.org/10.1136/bcr-2020-235425DOI Listing

Value of metabolic parameters in distinguishing primary mediastinal lymphomas from thymic epithelial tumors.

Cancer Biol Med 2020 May;17(2):468-477

Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.

A high rate of unnecessary thymectomies has been reported. This study aimed to distinguish primary mediastinal lymphomas (PMLs) from thymic epithelial tumors (TETs) by evaluating volumetric and metabolic parameters with F-FDG PET/CT. A total of 136 patients who were pathologically diagnosed with TETs or PMLs were enrolled, and F-FDG PET/CT was performed before therapy. Read More

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http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309468PMC

Are volume-dependent parameters in positron emission tomography predictive of postoperative recurrence after resection in patients with thymic carcinoma?

Surg Today 2020 Jun 13. Epub 2020 Jun 13.

Department of Thoracic Surgery, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 604-0984, Japan.

This study aimed to investigate the association between the volume-dependent parameters in F-fluorodeoxyglucose-positron emission tomography (F-FDG PET/CT) and a recurrence of thymic carcinoma. A retrospective chart review was performed based on our multi-institutional database to identify patients undergoing PET prior to resection of thymic carcinoma or neuroendocrine carcinoma between 1991 and 2018. The PET parameters (metabolic tumor volume and total lesion glycolysis) were evaluated retrospectively. Read More

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http://dx.doi.org/10.1007/s00595-020-02045-zDOI Listing

EUS Ablation in a Patient with Multiple Metastatic Pancreatic Tumors from ACTH-producing Thymic Neuroendocrine Neoplasm.

Dig Endosc 2020 May 27. Epub 2020 May 27.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Adrenocorticotropic hormone (ACTH)-producing neuroendocrine neoplasm (NEN) of the thymus is rare. Lymph nodes and bones are the most common metastatic sites. Most cases present with florid Cushing's syndrome (CS). Read More

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http://dx.doi.org/10.1111/den.13752DOI Listing

Recurrent Thymoma-Associated Paraneoplastic Encephalitis Resulting From Multiple Antibodies: A Case Report.

Neurohospitalist 2020 Apr 13;10(2):139-142. Epub 2019 Oct 13.

Department of Neurology, MedStar Georgetown University Hospital, Washington, DC, USA.

Few reports describe the clinical course and acute-care management of patients with recurrent multi-antibody paraneoplastic encephalitis. We describe a rare case of a patient having thymoma with multiple paraneoplastic syndromes who was found to have antibodies to α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) followed by -methyl-d-aspartate (NMDA) receptor in the setting of residual thymic tissue. He initially presented to the hospital with severe, rapidly progressive encephalitis with simultaneous antibodies to AMPA and voltage-gated potassium channel complex receptor. Read More

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http://dx.doi.org/10.1177/1941874419880423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191667PMC

Computed tomography (CT)-derived radiomic features differentiate prevascular mediastinum masses as thymic neoplasms versus lymphomas.

Radiol Med 2020 Apr 18. Epub 2020 Apr 18.

Department of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini, 4, 20090, Pieve Emanuele, Milano, Italy.

Objectives: We aimed to assess the ability of radiomics, applied to not-enhanced computed tomography (CT), to differentiate mediastinal masses as thymic neoplasms vs lymphomas.

Methods: The present study was an observational retrospective trial. Inclusion criteria were pathology-proven thymic neoplasia or lymphoma with mediastinal localization, availability of CT. Read More

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http://dx.doi.org/10.1007/s11547-020-01188-wDOI Listing

Predictive Features of Thymic Carcinoma and High-Risk Thymomas Using Random Forest Analysis.

J Comput Assist Tomogr 2020 Jan 28. Epub 2020 Jan 28.

From the The Second School of Clinical Medicine, Southern Medical University, and Department of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou.

Purpose: To determine the predictive features of thymic carcinomas and high-risk thymomas using random forest algorithm.

Methods: A total of 137 patients with pathologically confirmed high-risk thymomas and thymic carcinomas were enrolled in this study. Three clinical features and 20 computed tomography features were reviewed. Read More

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http://dx.doi.org/10.1097/RCT.0000000000000953DOI Listing
January 2020
1.602 Impact Factor

Distribution of Mediastinal Lesions Across Multi-Institutional, International, Radiology Databases.

J Thorac Oncol 2020 Apr 20;15(4):568-579. Epub 2019 Dec 20.

The Chaim Sheba Medical Center, affiliated with the Tel Aviv University, Tel Aviv, Israel.

Introduction: Mediastinal lesions are uncommon; studies on their distribution are, in general, small and from a single institution. Furthermore, these studies are usually based on pathology or surgical databases and, therefore, miss many lesions that did not undergo biopsy or resection. Our aim was to identify the distribution of lesions in the mediastinum in a large international, multi-institutional cohort. Read More

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http://dx.doi.org/10.1016/j.jtho.2019.12.108DOI Listing

Update in diagnostic imaging of the thymus and anterior mediastinal masses.

Gland Surg 2019 Sep;8(Suppl 3):S188-S207

Department of Medicine, Surgery and Neuro Sciences, Diagnostic Imaging, University of Siena, Azienda Ospedaliera Universitaria Senese, Siena, Italy.

Anterior mediastinal masses include a wide spectrum of malignant and benign pathologies with a large percentage represented by thymic lesions. Distinguishing these masses on diagnostic imaging is fundamental to guide the proper management for each patient. This review illustrates possibilities and limits of different imaging modalities to diagnose a lesion of the anterior mediastinum with particular attention to thymic disease. Read More

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http://dx.doi.org/10.21037/gs.2019.05.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755948PMC
September 2019
2 Reads

Challenges in diagnosing ectopic thymus tissue in children.

BMJ Case Rep 2019 Sep 17;12(9). Epub 2019 Sep 17.

Paediatrics, Antwerp University Hospital, University of Antwerp, Edegem, Belgium.

The presentation of a fast-growing cervical mass necessitates prompt attention due to risk of the mass effect on vital structures and requires preferential screening for infections, bleeding and malignancies in an extensive list of differential diagnoses. This case report describes a 4.5-year-old boy with a fast-growing, unilateral lesion in the neck, with clinical features in keeping with malignant characteristics. Read More

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http://dx.doi.org/10.1136/bcr-2018-228807DOI Listing
September 2019
2 Reads

Ectopic cervical thymus in children: Clinical and radiographic features.

Laryngoscope 2020 Jun 28;130(6):1577-1582. Epub 2019 Aug 28.

Department of Otolaryngology, Head & Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Objectives: Ectopic thymus is rare and can be a diagnostic challenge. This study evaluated the management of children radiographically diagnosed with ectopic cervical thymus.

Methods: A retrospective review of 100 patients was performed. Read More

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http://dx.doi.org/10.1002/lary.28248DOI Listing
June 2020
1 Read

The value of intraoperative parathyroid hormone assay in the surgery of mediastinal ectopic parathyroid adenoma (A case series).

Ann Med Surg (Lond) 2019 Aug 27;44:51-56. Epub 2019 Jun 27.

Department of Thoracic Surgery, CHU Hassan II, Fes, Morocco.

Background And Aims: Ectopic parathyroid adenoma is a rare entity. Its clinical management is challenging due to varying locations in the mediastinum. The aim of our study is to report our experience about the preoperative localization of the ectopic parathyroid adenoma and to emphasize the major role of the intraoperative parathyroid hormone assay in such circumstances. Read More

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http://dx.doi.org/10.1016/j.amsu.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610238PMC
August 2019
3 Reads

Thymic Tuberculosis Shown on FDG PET/CT Despite Coexisting Pulmonary Tuberculosis With No Increased FDG Activity.

Clin Nucl Med 2019 Oct;44(10):831-833

From the Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; and Hubei Key Laboratory of Molecular Imaging, Wuhan, China.

Extrapulmonary tuberculosis could involve multiple organs. However, thymic tuberculosis is relatively rare. We report a 21-year-old man who was referred for an F-FDG PET/CT imaging to assess his newly detected pulmonary nodule. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002697DOI Listing
October 2019
2 Reads

Ectopic hamartomatous thymoma in an immunocompromised male.

Pathol Res Pract 2019 Sep 10;215(9):152497. Epub 2019 Jun 10.

Northwestern University, 303 E Chicago Ave Ward 3-140 W127, Chicago, 60611, United States.

Ectopic hamartomatous thymoma (EHT) is a rare benign neoplasm classically occurring in the lower neck of adult males. Here we present a case of EHT occurring in a 43-year-old immunocompromised male and a brief review of existing literature. The patient presented with a palpable mass overlying the left clavicle which, on imaging, showed a solitary nodule possibly eroding the cortical bone. Read More

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http://dx.doi.org/10.1016/j.prp.2019.152497DOI Listing
September 2019
11 Reads

Cervical Thymic Cyst Around Hypoglossal Nerve.

J Craniofac Surg 2019 Jun;30(4):e295-e297

Department of Pathology, Ataturk University, Erzurum, Turkey.

Cervical thymic cyst is rare lesions leading to cervical mass. As it is a rare entity, it might be confused with other congenital neck masses or neoplastic lesions. Preoperative diagnosis is almost impossible. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005155DOI Listing
June 2019
7 Reads

Quantitative Thoracic Magnetic Resonance Criteria for the Differentiation of Cysts from Solid Masses in the Anterior Mediastinum.

Korean J Radiol 2019 05;20(5):854-861

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Objective: To evaluate quantitative magnetic resonance imaging (MRI) parameters for differentiation of cysts from and solid masses in the anterior mediastinum.

Materials And Methods: The development dataset included 18 patients from two institutions with pathologically-proven cysts (n = 6) and solid masses (n = 12) in the anterior mediastinum. We measured the maximum diameter, normalized T1 and T2 signal intensity (nT1 and nT2), normalized apparent diffusion coefficient (nADC), and relative enhancement ratio (RER) of each lesion. Read More

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http://dx.doi.org/10.3348/kjr.2018.0699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470082PMC
May 2019
4 Reads
1.807 Impact Factor

Role of advanced magnetic resonance imaging in the assessment of malignancies of the mediastinum.

World J Radiol 2019 Mar;11(3):27-45

MR imaging Unit, Clínica Las Nieves, Jaen 23007, Spain.

In the new era of functional magnetic resonance imaging (MRI), the utility of chest MRI is increasing exponentially due to several advances, including absence of ionizing radiation, excellent tissue contrast and high capability for lesion characterization and treatment monitoring. The application of several of these diagnostic weapons in a multiparametric fashion enables to better characterize thymic epithelial tumors and other mediastinal tumoral lesions, accurate assessment of the invasion of adjacent structures and detection of pathologic lymph nodes and metastasis. Also, "do not touch lesions" could be identified with the associated impact in the management of those patients. Read More

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http://dx.doi.org/10.4329/wjr.v11.i3.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441936PMC
March 2019
11 Reads

Distinguishing between Thymic Epithelial Tumors and Benign Cysts via Computed Tomography.

Korean J Radiol 2019 Apr;20(4):671-682

Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.

Objective: To investigate whether computed tomography (CT) and fluorine-18-labeled fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) may be applied to distinguish thymic epithelial tumors (TETs) from benign cysts in the anterior mediastinum.

Materials And Methods: We included 262 consecutive patients with pathologically proven TETs and benign cysts 5 cm or smaller who underwent preoperative CT scans. In addition to conventional morphological and ancillary CT findings, the relationship between the lesion and the adjacent mediastinal pleura was evaluated qualitatively and quantitatively. Read More

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http://dx.doi.org/10.3348/kjr.2018.0400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424822PMC
April 2019
6 Reads

Micronodular thymoma with lymphoid stroma diagnosed 10 years after the first operation: a case report.

J Med Case Rep 2019 Mar 16;13(1):69. Epub 2019 Mar 16.

Division of Thoracic Surgery, Respiratory Disease Center, Seirei Mikatahara General Hospital, 3453, Mikatahara-cho, Kita-ku Hamamatsu, Shizuoka, Japan.

Introduction: Micronodular thymoma with lymphoid stroma is a rare subtype of thymoma. Here we report a case of micronodular thymoma with lymphoid stroma that was completely resected after incomplete resection 10 years earlier.

Case Presentation: A 70-year-old Japanese woman who had undergone resection for a thymic cyst 10 years earlier was found to have a solid nodule with a multilocular lesion at the site of the previous operation. Read More

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http://dx.doi.org/10.1186/s13256-019-2006-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420736PMC
March 2019
5 Reads

Thoracoscopic Thymectomy for Large Thymic Cyst: Myasthenia Gravis With Thymoma Concealed by Thymic Cyst.

Surg Laparosc Endosc Percutan Tech 2019 Jun;29(3):e34-e36

Department of Surgery, Division of Chest Surgery.

We herein report a case of myasthenia gravis (MG) in which thoracoscopic thymectomy was performed for a large thymic cystic lesion using a subxiphoid approach. We have previously suggested the usefulness of the subxiphoid approach in thymectomy. The indications of thoracoscopic thymectomy were recently expanded to include large thymic cystic lesions without intraoperative rupture of the lesions. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000641DOI Listing
June 2019
3 Reads

Growth of thymic epithelial tumors and thymic cysts: Differential radiological points.

Thorac Cancer 2019 04 21;10(4):864-871. Epub 2019 Feb 21.

Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, South Korea.

Background: The growth rate of thymic epithelial tumors (TETs) and thymic cysts was investigated to determine whether they can be differentiated and clinico-radiological predictors of interval growth was identified.

Methods: This retrospective study included 122 patients with pathologically proven thymic cysts (n = 56) or TETs (n = 66) who underwent two serial chest computed tomography scans at least eight weeks apart. Average diameters and attenuation were measured, volume-doubling times (VDTs) were calculated, and clinical characteristics were recorded. Read More

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http://dx.doi.org/10.1111/1759-7714.13016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449257PMC
April 2019
1 Read
1.126 Impact Factor

Incidence and clinical variable inter-relationships of thymic epithelial tumors in northwest China.

J Thorac Dis 2018 Dec;10(12):6794-6802

Department of Radiology & Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University (Air Force Medical University), Xi'an 710038, China.

Background: Thymic epithelial tumors (TETs) are the most common primary thymus tumors, but neither the possible ethnical/regional differences in the incidence of TETs nor the inter-relationships among the clinical variables has been revealed in northwest China.

Methods: A retrospective chart review was performed among pathologically confirmed TET patients from January 2004 to December 2015 in a tertiary general hospital of northwest China and the incidence, clinical features and the inter-relationships among clinical variables were analyzed.

Results: A total of 603 pathologically confirmed TETs patients (age range, 5-78 years; 308 males) were enrolled and the most common lesion location was anterior mediastinum (98. Read More

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http://dx.doi.org/10.21037/jtd.2018.11.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344759PMC
December 2018
26 Reads

A case of brain metastasis of a thymic carcinoma with a review of the literature.

Neurochirurgie 2019 Feb 30;65(1):43-48. Epub 2019 Jan 30.

Department of neurosurgery, CHU-hôpital Nord, Marseille, France.

Thymic epithelial tumors (TET) are rare lesions. The brain metastases of these tumors are even rarer. We report a case of brain metastases in a known patient with a thymic carcinoma diagnosed in October 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00283770193000
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http://dx.doi.org/10.1016/j.neuchi.2018.09.004DOI Listing
February 2019
35 Reads

Thymoma with an isolated splenic metastasis eight years after extended thymectomy: a case report.

BMC Cancer 2018 Dec 13;18(1):1249. Epub 2018 Dec 13.

Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.

Background: Thymomas are typically slow-growing tumors and AB type thymomas are considered no/low risk tumors with a better prognosis. Extra-thoracic metastases are extremely rare. To the best of our knowledge, no patient with an isolated splenic metastasis from a thymoma has been reported. Read More

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
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http://dx.doi.org/10.1186/s12885-018-5165-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293546PMC
December 2018
29 Reads

99mTc-MIBI Uptake in a Benign Thymic Cyst.

Clin Nucl Med 2019 Feb;44(2):150-152

Department of Pathology, Westchester Medical Center, Valhalla, NY.

A 34-year-old man with end-stage renal failure status post rejection of a deceased donor kidney transplant presented with bone pain in the setting of elevated serum parathyroid hormone and calcium levels. A Tc-MIBI SPECT/CT was performed before planned subtotal parathyroidectomy. SPECT/CT imaging revealed a 1. Read More

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http://Insights.ovid.com/crossref?an=00003072-900000000-9734
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http://dx.doi.org/10.1097/RLU.0000000000002382DOI Listing
February 2019
31 Reads

[A Case of Carcinoma Showing Thymus-Like Differentiation (CASTLE) of the Thyroid].

J UOEH 2018;40(3):259-266

Department of Surgery 1, School of Medicine, University of Occupational and Environmental Health, Japan.

The case presented herein was a 70-year-old woman who had no compliant, but had a mass in the lower part of the right lobe of the thyroid detected by ultrasound (US). The US image of the tumor, measuring 13 mm in diameter, showed a low and heterogeneous internal echo level with calcification and an irregular margin. The tumor appeared to extend to the adjacent sternothyroid muscle, and cervical lymph node swelling was detected in a computer tomography (CT) image, but no metastatic lesion was found by positron emission tomography (PET)-CT. Read More

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https://www.jstage.jst.go.jp/article/juoeh/40/3/40_259/_arti
Publisher Site
http://dx.doi.org/10.7888/juoeh.40.259DOI Listing
March 2019
47 Reads

Occurrence of thymic pathology in two families. Is familial screening justified?

Monaldi Arch Chest Dis 2018 09 4;88(3):913. Epub 2018 Sep 4.

Athens Naval and Veterans Hospital, Department of Thoracic Surgery.

The familial occurrence of thymic pathology, even though rare, is widely reported in the literature and mainly concerns cases of familial autoimmune myasthenia gravis. Other less frequent cases of familial occurrence of thymoma, thymic carcinoid and thymic hyperplasia have been described. It seems that the familial occurrence is poorly recorded and thus its prevalence is underestimated. Read More

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http://dx.doi.org/10.4081/monaldi.2018.913DOI Listing
September 2018
34 Reads

Useful computed tomography features for differentiating between focal atelectasis and pleural dissemination on preoperative evaluations of thymic epithelial tumors.

Eur J Radiol 2018 Jun 7;103:38-43. Epub 2018 Apr 7.

Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Purpose: Distinguishing between focal atelectasis (FA) and pleural dissemination (PD) is important for determining the optimal therapeutic strategy for thymic epithelial tumors (TET). This study aimed to identify useful computed tomography (CT) features for distinguishing between these two conditions.

Materials And Methods: We retrospectively analyzed preoperative CT images of 27 TET, which included 40 PD and 40 FA lesions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183012
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http://dx.doi.org/10.1016/j.ejrad.2018.04.001DOI Listing
June 2018
9 Reads

Intrathyroidal ectopic thymus in children: A benign lesion.

Medicine (Baltimore) 2018 Apr;97(14):e0282

Department of Pediatrics.

As ultrasound is commonly used these days, more and more lesions are found incidentally, including simple cysts, isoechoic nodules, and hypoechoic nodules, such as ectopic thymus. We here report the prevalence of ectopic thymus and its natural course.We retrospectively reviewed the charts of 690 subjects (342 males, 348 females) who were under 18 years old and had undergone neck or thyroid ultrasound at Hallym University Sacred Heart Hospital from January 2014 to June 2017. Read More

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http://dx.doi.org/10.1097/MD.0000000000010282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902273PMC
April 2018
6 Reads

Cytomorphology and sonographic features of ectopic thymic tissue diagnosed in paediatric FNA biopsies.

Cytopathology 2018 06 26;29(3):241-246. Epub 2018 Mar 26.

Department of Pathology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, USA.

Introduction: Ectopic thymic tissue can arise as an asymptomatic neck mass, which may be detected on imaging studies. The aim of this study was to determine the incidence of ectopic thymic tissue in paediatric FNAs and to the correlate clinical, radiological and cytomorphological findings.

Methods: FNAs in children with neck and mediastinal lesions performed between January 2012 and July 2016 were reviewed for cases of ectopic thymus. Read More

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http://dx.doi.org/10.1111/cyt.12529DOI Listing
June 2018
5 Reads

Radiographic Predictors of Resectability in Thymic Carcinoma.

Ann Thorac Surg 2018 07 11;106(1):242-248. Epub 2018 Mar 11.

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

Background: The aim of this study was to assess preoperative computed tomography characteristics of thymic carcinomas and to investigate which features could predict an incomplete surgical resection. A secondary aim was to correlate preoperative imaging features with Masaoka stage.

Methods: In this study, approved by our Institutional Review Board, two readers retrospectively reviewed preoperative computed tomography scans at our tertiary referral oncology center between 1994 and 2014. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853178PMC
July 2018
9 Reads

Intrathyroidal thymic tissue in children: Avoiding unnecessary surgery.

J Pediatr Surg 2018 May 8;53(5):1010-1013. Epub 2018 Feb 8.

Division of Pediatric General and Thoracic Surgery, The Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:

Background/purpose: Intrathyroidal thymic tissue may be misinterpreted as a thyroid lesion in children, leading to invasive tests or resection. We sought to describe the characteristic imaging features of these lesions and to evaluate the safety of non-operative management.

Methods: A retrospective review of all patients less than 18years old with intrathyroidal thymic tissue from 2000 to 2016 was performed. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.011DOI Listing
May 2018
4 Reads

Dedifferentiated primary mediastinal liposarcoma mimicking a thymic tumor.

Pathologica 2017 Dec;109(4):401-404

Paris V University.

Mediastinal tumors are heterogeneous and the diagnosis depends on their location in the mediastinum. The most frequent tumors are germinal tumor, lymphoma and thymoma. The clinical and radiological aspects are often not sufficient to orient the diagnosis and biopsy is necessary to confirmed it. Read More

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December 2017
4 Reads

An assessment of F-FDG PET/CT for thoracic screening and risk stratification of pulmonary nodules in multiple endocrine neoplasia type 1.

Clin Endocrinol (Oxf) 2018 05 6;88(5):683-691. Epub 2018 Mar 6.

Department of Diabetes & Endocrinology, Royal Hobart Hospital, Hobart, TAS, Australia.

Context: Bronchopulmonary neuroendocrine tumours (bpNETs) and thymic carcinoid (ThC) are features of multiple endocrine neoplasia type 1 (MEN 1), and surveillance guidelines recommend periodic thoracic imaging. The optimal thoracic imaging modality and screening frequency remain uncertain as does the prognosis of small lung nodules when identified.

Objectives: To evaluate fluorodeoxyglucose positron emission tomography/computed tomography ( F-FDG PET/CT) for identification and prognostic assessment of thoracic lesions in MEN 1. Read More

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http://dx.doi.org/10.1111/cen.13573DOI Listing
May 2018
17 Reads

Lateral cervical thymic cyst in a child: a case report.

BMC Res Notes 2018 Jan 30;11(1):85. Epub 2018 Jan 30.

Department of Pathology, FMFM-UCAM-CHU Mohammed VI-50 Assif, 40000, Marrakech, Morocco.

Background: Cervical thymic cysts are uncommon lesions, rarely considered in the differential diagnosis of neck cysts in children.

Case Presentation: We report a rare case of multiloculated thymic cyst in an 8-year-old boy on the right side of the neck. Perioperative diagnosis was a cystic hygroma. Read More

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http://dx.doi.org/10.1186/s13104-018-3208-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791249PMC
January 2018
4 Reads

Mediastinal and Pleural MR Imaging: Practical Approach for Daily Practice.

Radiographics 2018 Jan-Feb;38(1):37-55

From the Mallinckrodt Institute of Radiology, 510 S. Kingshighway Blvd, Campus Box 8131, St Louis, MO 63110 (C.A.R., S.R.M., K.L.R., S.B.); Department of Radiology, Hospital Cruz Roja, Córdoba, Spain (J.B.); and Department of Radiology, Weill Medical College, New York-Presbyterian Hospital, New York, NY (D.B.G.).

Radiologists in any practice setting should be prepared to use thoracic magnetic resonance (MR) imaging for noncardiac and nonangiographic applications. This begins with understanding the sequence building blocks that can be used to design effective thoracic MR imaging protocols. In most instances, the sequences used in thoracic MR imaging are adapted from protocols used elsewhere in the body. Read More

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http://dx.doi.org/10.1148/rg.2018170091DOI Listing
August 2018
10 Reads

Identification of the pericardiacophrenic vein on CT.

Cancer Imaging 2018 Jan 5;18(1). Epub 2018 Jan 5.

Department of Radiology, Nagoya City University, Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.

Background: To evaluate the depictability of pericardiacophrenic veins (PCPV) as landmarks for the location of the phrenic nerves on multi-detector-row computed tomography (MDCT), and to investigate the usefulness of depicting the PCPV to aid differential diagnosis of anterior mediastinal lesions.

Methods: Fifty-six patients with anterior mediastinal lesions (Fifty lesions originated from the thymus, six were of non-thymic origin) were evaluated. Contrast-enhanced CT scans of the chest were performed in all cases before diagnosis, and 22 of these scans were performed with electrocardiographic (ECG) gating. Read More

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http://dx.doi.org/10.1186/s40644-017-0134-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756428PMC
January 2018
4 Reads

Coexisting Thymic and Pulmonary Carcinoid Tumors Associated with Multiple Endocrine Neoplasia Type1.

Ann Thorac Cardiovasc Surg 2018 Jun 26;24(3):147-150. Epub 2017 Oct 26.

Department of Pathology, National Hospital Organization Kyoto Medical Center, Kyoto, Kyoto, Japan.

An anterior mediastinal tumor was detected in a 45-year-old female during a medical checkup. Chest computed tomography (CT) showed the anterior mediastinal tumor and a pulmonary tumor in the right lower lobe. Furthermore, tumors of the parathyroid gland, pancreas, and pituitary gland were also detected. Read More

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http://dx.doi.org/10.5761/atcs.cr.17-00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033522PMC
June 2018
11 Reads

Ectopic Intrathyroidal Thymic Tissue Mimicking Thyroid Nodules in Children.

J Ultrasound Med 2018 Mar 29;37(3):783-791. Epub 2017 Aug 29.

Thyroid Section, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Ectopic intrathyroidal thymic tissue is a benign lesion of nonthyroid origin occasionally found in the pediatric thyroid gland. Accurate diagnosis of such lesions is critical to avoid unnecessary biopsy or surgery. Twelve children referred to our center for the concern of thyroid nodules were found to have intrathyroidal thymic tissue. Read More

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http://dx.doi.org/10.1002/jum.14360DOI Listing
March 2018
20 Reads

Assessment of Mediastinal Tumors Using SUV and Volumetric Parameters on FDG-PET/CT.

Asia Ocean J Nucl Med Biol 2017 ;5(1):22-29

Department of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, Suita, Japan.

Objectives: This study aimed to evaluate the role of pretreatment SUV and volumetric FDG positron emission tomography (PET) parameters in the differentiation between benign and malignant mediastinal tumors. In addition, we investigated whether pretreatment SUV and volumetric FDG-PET parameters could distinguish thymomas from thymic carcinomas, and low-risk from high-risk thymomas.

Methods: This study was conducted on 52 patients with mediastinal tumors undergoing FDG-PET/CT. Read More

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http://dx.doi.org/10.22038/aojnmb.2016.7996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221681PMC
January 2017
50 Reads

Factors causing loss of normal Doppler waveform of the left internal jugular vein: evaluation on chest computed tomography.

J Vasc Access 2017 Sep 19;18(5):402-407. Epub 2017 Jul 19.

Department of Radiology, Korea University Guro Hospital, Korea University College of Medicine, Seoul - Korea.

Purpose: To evaluate the presence and causes of left brachiocephalic vein (LBCV) steno-occlusive lesions in patients with loss of normal waveform in Doppler ultrasound of the left internal jugular vein (LIJV).

Materials And Methods: We performed Doppler ultrasound of both internal jugular veins in 1912 patients who received an implantable venous access port from August 2013 to January 2016. Among them, 106 patients showed loss of normal Doppler waveforms of the LIJV (56 men and 50 women; mean age, 61. Read More

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http://dx.doi.org/10.5301/jva.5000750DOI Listing
September 2017
31 Reads

[Seminoma of the Mediastinum with Cystic Change;Report of a Case].

Kyobu Geka 2017 Jul;70(7):545-547

Department of Thoracic Surgery, Higashihiroshima Medical Center, Hiroshima, Japan.

The patient was a 25-year-old man. He was diagnosed as having a mediastinal tumor based on chest radiography. Chest computed tomography and magnetic resonance imaging revealed a cystic tumor in the anterior mediastinum. Read More

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July 2017
58 Reads

Chest-MRI under pulsatile flow ventilation: A new promising technique.

PLoS One 2017 12;12(6):e0178807. Epub 2017 Jun 12.

Department of Radiation Oncology, CHUV and University of Lausanne, Lausanne, Switzerland.

Objectives: Magnetic resonance imaging (MRI) of the chest has long suffered from its sensitivity to respiratory and cardiac motion with an intrinsically low signal to noise ratio and a limited spatial resolution. The purpose of this study was to perform chest MRI under an adapted non invasive pulsatile flow ventilation system (high frequency percussive ventilation, HFPV®) allowing breath hold durations 10 to 15 times longer than other existing systems.

Methods: One volunteer and one patient known for a thymic lesion underwent a chest MRI under ventilation percussion technique (VP-MR). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178807PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467845PMC
September 2017
64 Reads

Prognostic models for primary mediastinal (thymic) B-cell lymphoma derived from 18-FDG PET/CT quantitative parameters in the International Extranodal Lymphoma Study Group (IELSG) 26 study.

Br J Haematol 2017 08 9;178(4):588-591. Epub 2017 May 9.

Cancer Research UK Centre, Southampton General Hospital, Southampton, United Kingdom.

The International Extranodal Lymphoma Study Group-26 study evaluated the prognostic role of 18-fluorodeoxyglucose positron-emission tomography (PET) in primary mediastinal large B-cell lymphoma. We assessed quantitative PET parameters at diagnosis and post-treatment in 100 patients. The end-of-therapy total lesion glycolysis (TLG) was the best individual outcome predictor, but the combination of baseline TLG and end-of-therapy visual analysis with Deauville Score (DS) showed a better positive predictive value. Read More

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http://dx.doi.org/10.1111/bjh.14728DOI Listing
August 2017
46 Reads

Intrathyroidal ectopic thymus in children: a sonographic survey.

Med Ultrason 2017 Apr;19(2):179-184

Department of Radiology, Akdeniz University Hospital, Antalya, Turkey.

Aims: Intrathyroidal ectopic thymus (IET) is being increasingly reported in the radiology literature. Most of the reports are of individual cases or small series and prevalence and natural course of the pathology is not well known. The purpose of this study is to establish the prevalence of IET in children and report long term follow-up results. Read More

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https://www.medultrason.ro/medultrason/index.php/medultrason
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http://dx.doi.org/10.11152/mu-913DOI Listing
April 2017
7 Reads

Thymoma metastatic to liver and pancreas: case report and review of the literature.

J Int Med Res 2017 Apr 13;45(2):868-874. Epub 2017 Feb 13.

1 Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, Padua, Italy.

A 71-year-old man presented with a thymic mass involving the superior vena cava. A mediastinoscopical biopsy initially suggested a diagnosis of type A thymoma. After neoadjuvant chemotherapy, the patient underwent en-bloc thymectomy and vascular resection for a pathology-confirmed type B3 thymoma involving the superior vena cava, the left brachiocephalic vein and the distal part of the right brachiocephalic vein. Read More

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http://dx.doi.org/10.1177/0300060516680673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536659PMC
April 2017
3 Reads

Evaluation of metabolic response with F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors.

Cancer Imaging 2017 Mar 7;17(1):10. Epub 2017 Mar 7.

Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, Edificio 10, 80131, Naples, Italy.

Background: Patients with advanced or recurrent thymic epithelial tumors (TETs) often need several consecutive lines of chemotherapy. The aim of this retrospective monocentric study was to test whether F-Fluorodeoxyglucose positron emission tomography-computed tomography (F-FDG PET-CT) is able to monitor standard chemotherapy efficacy in those patients and whether metabolic response correlates with morphovolumetric response as assessed by Response Evaluation Criteria in Solid Tumor (RECIST).

Methods: We evaluated 27 consecutive patients with advanced (16 patients) or recurrent (11 patients) TETs. Read More

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http://cancerimagingjournal.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s40644-017-0112-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339950PMC
March 2017
46 Reads

Diagnosis and Management of Cervical Thymic Cysts in Children.

Cureus 2017 Jan 11;9(1):e973. Epub 2017 Jan 11.

Department of Pediatric Otolaryngology, Children's Hospital of UPMC.

We present the case of a 10-year-old boy with the sudden onset of a large, painless left neck mass. Findings on magnetic resonance imaging (MRI) and fine needle aspiration (FNA) biopsy suggest a cystic lesion, most likely of thymic origin. Cervical thymic cysts are a rare form of cervical mass, which are easily overlooked in the differential diagnosis of children presenting with painless neck masses. Read More

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http://dx.doi.org/10.7759/cureus.973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298914PMC
January 2017
19 Reads

Ectopic intrathyroidal thymus in children: Prevalence, imaging findings and evolution.

Turk J Pediatr 2017 ;59(4):387-394

Department of Radiology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.

Erol OB, Şahin D, Bayramoğlu Z, Yılmaz R, Akpınar YE, Ünal ÖF, Yekeler E. Ectopic intrathyroidal thymus in children: Prevalence, imaging findings and evolution. Turk J Pediatr 2017; 59: 387-394. Read More

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http://www.turkishjournalpediatrics.org/doi.php?doi=10.24953
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http://dx.doi.org/10.24953/turkjped.2017.04.004DOI Listing
December 2018
12 Reads