183 results match your criteria Thymic Lesion Imaging


Incidence and clinical variable inter-relationships of thymic epithelial tumors in northwest China.

J Thorac Dis 2018 Dec;10(12):6794-6802

Department of Radiology & Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University (Air Force Medical University), Xi'an 710038, China.

Background: Thymic epithelial tumors (TETs) are the most common primary thymus tumors, but neither the possible ethnical/regional differences in the incidence of TETs nor the inter-relationships among the clinical variables has been revealed in northwest China.

Methods: A retrospective chart review was performed among pathologically confirmed TET patients from January 2004 to December 2015 in a tertiary general hospital of northwest China and the incidence, clinical features and the inter-relationships among clinical variables were analyzed.

Results: A total of 603 pathologically confirmed TETs patients (age range, 5-78 years; 308 males) were enrolled and the most common lesion location was anterior mediastinum (98. Read More

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http://dx.doi.org/10.21037/jtd.2018.11.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344759PMC
December 2018

Thymoma with an isolated splenic metastasis eight years after extended thymectomy: a case report.

BMC Cancer 2018 Dec 13;18(1):1249. Epub 2018 Dec 13.

Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.

Background: Thymomas are typically slow-growing tumors and AB type thymomas are considered no/low risk tumors with a better prognosis. Extra-thoracic metastases are extremely rare. To the best of our knowledge, no patient with an isolated splenic metastasis from a thymoma has been reported. Read More

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
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http://dx.doi.org/10.1186/s12885-018-5165-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293546PMC
December 2018
6 Reads

99mTc-MIBI Uptake in a Benign Thymic Cyst.

Clin Nucl Med 2019 Feb;44(2):150-152

Department of Pathology, Westchester Medical Center, Valhalla, NY.

A 34-year-old man with end-stage renal failure status post rejection of a deceased donor kidney transplant presented with bone pain in the setting of elevated serum parathyroid hormone and calcium levels. A Tc-MIBI SPECT/CT was performed before planned subtotal parathyroidectomy. SPECT/CT imaging revealed a 1. Read More

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http://Insights.ovid.com/crossref?an=00003072-900000000-9734
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http://dx.doi.org/10.1097/RLU.0000000000002382DOI Listing
February 2019
11 Reads

Useful computed tomography features for differentiating between focal atelectasis and pleural dissemination on preoperative evaluations of thymic epithelial tumors.

Eur J Radiol 2018 Jun 7;103:38-43. Epub 2018 Apr 7.

Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Purpose: Distinguishing between focal atelectasis (FA) and pleural dissemination (PD) is important for determining the optimal therapeutic strategy for thymic epithelial tumors (TET). This study aimed to identify useful computed tomography (CT) features for distinguishing between these two conditions.

Materials And Methods: We retrospectively analyzed preoperative CT images of 27 TET, which included 40 PD and 40 FA lesions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183012
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http://dx.doi.org/10.1016/j.ejrad.2018.04.001DOI Listing
June 2018
4 Reads

Intrathyroidal ectopic thymus in children: A benign lesion.

Medicine (Baltimore) 2018 Apr;97(14):e0282

Department of Pediatrics.

As ultrasound is commonly used these days, more and more lesions are found incidentally, including simple cysts, isoechoic nodules, and hypoechoic nodules, such as ectopic thymus. We here report the prevalence of ectopic thymus and its natural course.We retrospectively reviewed the charts of 690 subjects (342 males, 348 females) who were under 18 years old and had undergone neck or thyroid ultrasound at Hallym University Sacred Heart Hospital from January 2014 to June 2017. Read More

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http://dx.doi.org/10.1097/MD.0000000000010282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902273PMC
April 2018
2 Reads

Cytomorphology and sonographic features of ectopic thymic tissue diagnosed in paediatric FNA biopsies.

Cytopathology 2018 06 26;29(3):241-246. Epub 2018 Mar 26.

Department of Pathology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, USA.

Introduction: Ectopic thymic tissue can arise as an asymptomatic neck mass, which may be detected on imaging studies. The aim of this study was to determine the incidence of ectopic thymic tissue in paediatric FNAs and to the correlate clinical, radiological and cytomorphological findings.

Methods: FNAs in children with neck and mediastinal lesions performed between January 2012 and July 2016 were reviewed for cases of ectopic thymus. Read More

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http://dx.doi.org/10.1111/cyt.12529DOI Listing
June 2018
2 Reads

Radiographic Predictors of Resectability in Thymic Carcinoma.

Ann Thorac Surg 2018 Jul 11;106(1):242-248. Epub 2018 Mar 11.

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

Background: The aim of this study was to assess preoperative computed tomography characteristics of thymic carcinomas and to investigate which features could predict an incomplete surgical resection. A secondary aim was to correlate preoperative imaging features with Masaoka stage.

Methods: In this study, approved by our Institutional Review Board, two readers retrospectively reviewed preoperative computed tomography scans at our tertiary referral oncology center between 1994 and 2014. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.02.019DOI Listing
July 2018
4 Reads

Intrathyroidal thymic tissue in children: Avoiding unnecessary surgery.

J Pediatr Surg 2018 May 8;53(5):1010-1013. Epub 2018 Feb 8.

Division of Pediatric General and Thoracic Surgery, The Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:

Background/purpose: Intrathyroidal thymic tissue may be misinterpreted as a thyroid lesion in children, leading to invasive tests or resection. We sought to describe the characteristic imaging features of these lesions and to evaluate the safety of non-operative management.

Methods: A retrospective review of all patients less than 18years old with intrathyroidal thymic tissue from 2000 to 2016 was performed. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.011DOI Listing
May 2018
1 Read

An assessment of F-FDG PET/CT for thoracic screening and risk stratification of pulmonary nodules in multiple endocrine neoplasia type 1.

Clin Endocrinol (Oxf) 2018 May 6;88(5):683-691. Epub 2018 Mar 6.

Department of Diabetes & Endocrinology, Royal Hobart Hospital, Hobart, TAS, Australia.

Context: Bronchopulmonary neuroendocrine tumours (bpNETs) and thymic carcinoid (ThC) are features of multiple endocrine neoplasia type 1 (MEN 1), and surveillance guidelines recommend periodic thoracic imaging. The optimal thoracic imaging modality and screening frequency remain uncertain as does the prognosis of small lung nodules when identified.

Objectives: To evaluate fluorodeoxyglucose positron emission tomography/computed tomography ( F-FDG PET/CT) for identification and prognostic assessment of thoracic lesions in MEN 1. Read More

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http://dx.doi.org/10.1111/cen.13573DOI Listing
May 2018
10 Reads

Lateral cervical thymic cyst in a child: a case report.

BMC Res Notes 2018 Jan 30;11(1):85. Epub 2018 Jan 30.

Department of Pathology, FMFM-UCAM-CHU Mohammed VI-50 Assif, 40000, Marrakech, Morocco.

Background: Cervical thymic cysts are uncommon lesions, rarely considered in the differential diagnosis of neck cysts in children.

Case Presentation: We report a rare case of multiloculated thymic cyst in an 8-year-old boy on the right side of the neck. Perioperative diagnosis was a cystic hygroma. Read More

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http://dx.doi.org/10.1186/s13104-018-3208-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791249PMC
January 2018
1 Read

Mediastinal and Pleural MR Imaging: Practical Approach for Daily Practice.

Radiographics 2018 Jan-Feb;38(1):37-55

From the Mallinckrodt Institute of Radiology, 510 S. Kingshighway Blvd, Campus Box 8131, St Louis, MO 63110 (C.A.R., S.R.M., K.L.R., S.B.); Department of Radiology, Hospital Cruz Roja, Córdoba, Spain (J.B.); and Department of Radiology, Weill Medical College, New York-Presbyterian Hospital, New York, NY (D.B.G.).

Radiologists in any practice setting should be prepared to use thoracic magnetic resonance (MR) imaging for noncardiac and nonangiographic applications. This begins with understanding the sequence building blocks that can be used to design effective thoracic MR imaging protocols. In most instances, the sequences used in thoracic MR imaging are adapted from protocols used elsewhere in the body. Read More

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http://dx.doi.org/10.1148/rg.2018170091DOI Listing
August 2018
4 Reads

Identification of the pericardiacophrenic vein on CT.

Cancer Imaging 2018 Jan 5;18(1). Epub 2018 Jan 5.

Department of Radiology, Nagoya City University, Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.

Background: To evaluate the depictability of pericardiacophrenic veins (PCPV) as landmarks for the location of the phrenic nerves on multi-detector-row computed tomography (MDCT), and to investigate the usefulness of depicting the PCPV to aid differential diagnosis of anterior mediastinal lesions.

Methods: Fifty-six patients with anterior mediastinal lesions (Fifty lesions originated from the thymus, six were of non-thymic origin) were evaluated. Contrast-enhanced CT scans of the chest were performed in all cases before diagnosis, and 22 of these scans were performed with electrocardiographic (ECG) gating. Read More

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http://dx.doi.org/10.1186/s40644-017-0134-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756428PMC
January 2018
2 Reads

Coexisting Thymic and Pulmonary Carcinoid Tumors Associated with Multiple Endocrine Neoplasia Type1.

Ann Thorac Cardiovasc Surg 2018 Jun 26;24(3):147-150. Epub 2017 Oct 26.

Department of Pathology, National Hospital Organization Kyoto Medical Center, Kyoto, Kyoto, Japan.

An anterior mediastinal tumor was detected in a 45-year-old female during a medical checkup. Chest computed tomography (CT) showed the anterior mediastinal tumor and a pulmonary tumor in the right lower lobe. Furthermore, tumors of the parathyroid gland, pancreas, and pituitary gland were also detected. Read More

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http://dx.doi.org/10.5761/atcs.cr.17-00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033522PMC
June 2018
5 Reads

Ectopic Intrathyroidal Thymic Tissue Mimicking Thyroid Nodules in Children.

J Ultrasound Med 2018 Mar 29;37(3):783-791. Epub 2017 Aug 29.

Thyroid Section, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Ectopic intrathyroidal thymic tissue is a benign lesion of nonthyroid origin occasionally found in the pediatric thyroid gland. Accurate diagnosis of such lesions is critical to avoid unnecessary biopsy or surgery. Twelve children referred to our center for the concern of thyroid nodules were found to have intrathyroidal thymic tissue. Read More

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http://dx.doi.org/10.1002/jum.14360DOI Listing
March 2018
9 Reads

Assessment of Mediastinal Tumors Using SUV and Volumetric Parameters on FDG-PET/CT.

Asia Ocean J Nucl Med Biol 2017 ;5(1):22-29

Department of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, Suita, Japan.

Objectives: This study aimed to evaluate the role of pretreatment SUV and volumetric FDG positron emission tomography (PET) parameters in the differentiation between benign and malignant mediastinal tumors. In addition, we investigated whether pretreatment SUV and volumetric FDG-PET parameters could distinguish thymomas from thymic carcinomas, and low-risk from high-risk thymomas.

Methods: This study was conducted on 52 patients with mediastinal tumors undergoing FDG-PET/CT. Read More

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http://dx.doi.org/10.22038/aojnmb.2016.7996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221681PMC
January 2017
10 Reads

Factors causing loss of normal Doppler waveform of the left internal jugular vein: evaluation on chest computed tomography.

J Vasc Access 2017 Sep 19;18(5):402-407. Epub 2017 Jul 19.

Department of Radiology, Korea University Guro Hospital, Korea University College of Medicine, Seoul - Korea.

Purpose: To evaluate the presence and causes of left brachiocephalic vein (LBCV) steno-occlusive lesions in patients with loss of normal waveform in Doppler ultrasound of the left internal jugular vein (LIJV).

Materials And Methods: We performed Doppler ultrasound of both internal jugular veins in 1912 patients who received an implantable venous access port from August 2013 to January 2016. Among them, 106 patients showed loss of normal Doppler waveforms of the LIJV (56 men and 50 women; mean age, 61. Read More

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http://dx.doi.org/10.5301/jva.5000750DOI Listing
September 2017
21 Reads

[Seminoma of the Mediastinum with Cystic Change;Report of a Case].

Kyobu Geka 2017 Jul;70(7):545-547

Department of Thoracic Surgery, Higashihiroshima Medical Center, Hiroshima, Japan.

The patient was a 25-year-old man. He was diagnosed as having a mediastinal tumor based on chest radiography. Chest computed tomography and magnetic resonance imaging revealed a cystic tumor in the anterior mediastinum. Read More

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July 2017
23 Reads

Chest-MRI under pulsatile flow ventilation: A new promising technique.

PLoS One 2017 12;12(6):e0178807. Epub 2017 Jun 12.

Department of Radiation Oncology, CHUV and University of Lausanne, Lausanne, Switzerland.

Objectives: Magnetic resonance imaging (MRI) of the chest has long suffered from its sensitivity to respiratory and cardiac motion with an intrinsically low signal to noise ratio and a limited spatial resolution. The purpose of this study was to perform chest MRI under an adapted non invasive pulsatile flow ventilation system (high frequency percussive ventilation, HFPV®) allowing breath hold durations 10 to 15 times longer than other existing systems.

Methods: One volunteer and one patient known for a thymic lesion underwent a chest MRI under ventilation percussion technique (VP-MR). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178807PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467845PMC
September 2017
28 Reads

Prognostic models for primary mediastinal (thymic) B-cell lymphoma derived from 18-FDG PET/CT quantitative parameters in the International Extranodal Lymphoma Study Group (IELSG) 26 study.

Br J Haematol 2017 08 9;178(4):588-591. Epub 2017 May 9.

Cancer Research UK Centre, Southampton General Hospital, Southampton, United Kingdom.

The International Extranodal Lymphoma Study Group-26 study evaluated the prognostic role of 18-fluorodeoxyglucose positron-emission tomography (PET) in primary mediastinal large B-cell lymphoma. We assessed quantitative PET parameters at diagnosis and post-treatment in 100 patients. The end-of-therapy total lesion glycolysis (TLG) was the best individual outcome predictor, but the combination of baseline TLG and end-of-therapy visual analysis with Deauville Score (DS) showed a better positive predictive value. Read More

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http://dx.doi.org/10.1111/bjh.14728DOI Listing
August 2017
18 Reads

Intrathyroidal ectopic thymus in children: a sonographic survey.

Med Ultrason 2017 Apr;19(2):179-184

Department of Radiology, Akdeniz University Hospital, Antalya, Turkey.

Aims: Intrathyroidal ectopic thymus (IET) is being increasingly reported in the radiology literature. Most of the reports are of individual cases or small series and prevalence and natural course of the pathology is not well known. The purpose of this study is to establish the prevalence of IET in children and report long term follow-up results. Read More

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http://dx.doi.org/10.11152/mu-913DOI Listing
April 2017
3 Reads

Thymoma metastatic to liver and pancreas: case report and review of the literature.

J Int Med Res 2017 Apr 13;45(2):868-874. Epub 2017 Feb 13.

1 Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, Padua, Italy.

A 71-year-old man presented with a thymic mass involving the superior vena cava. A mediastinoscopical biopsy initially suggested a diagnosis of type A thymoma. After neoadjuvant chemotherapy, the patient underwent en-bloc thymectomy and vascular resection for a pathology-confirmed type B3 thymoma involving the superior vena cava, the left brachiocephalic vein and the distal part of the right brachiocephalic vein. Read More

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http://dx.doi.org/10.1177/0300060516680673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536659PMC
April 2017
1 Read

Evaluation of metabolic response with F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors.

Cancer Imaging 2017 Mar 7;17(1):10. Epub 2017 Mar 7.

Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, Edificio 10, 80131, Naples, Italy.

Background: Patients with advanced or recurrent thymic epithelial tumors (TETs) often need several consecutive lines of chemotherapy. The aim of this retrospective monocentric study was to test whether F-Fluorodeoxyglucose positron emission tomography-computed tomography (F-FDG PET-CT) is able to monitor standard chemotherapy efficacy in those patients and whether metabolic response correlates with morphovolumetric response as assessed by Response Evaluation Criteria in Solid Tumor (RECIST).

Methods: We evaluated 27 consecutive patients with advanced (16 patients) or recurrent (11 patients) TETs. Read More

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http://cancerimagingjournal.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s40644-017-0112-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339950PMC
March 2017
12 Reads

Diagnosis and Management of Cervical Thymic Cysts in Children.

Cureus 2017 Jan 11;9(1):e973. Epub 2017 Jan 11.

Department of Pediatric Otolaryngology, Children's Hospital of UPMC.

We present the case of a 10-year-old boy with the sudden onset of a large, painless left neck mass. Findings on magnetic resonance imaging (MRI) and fine needle aspiration (FNA) biopsy suggest a cystic lesion, most likely of thymic origin. Cervical thymic cysts are a rare form of cervical mass, which are easily overlooked in the differential diagnosis of children presenting with painless neck masses. Read More

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http://dx.doi.org/10.7759/cureus.973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298914PMC
January 2017
7 Reads

Ectopic intrathyroidal thymus in children: Prevalence, imaging findings and evolution.

Turk J Pediatr 2017 ;59(4):387-394

Department of Radiology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.

Erol OB, Şahin D, Bayramoğlu Z, Yılmaz R, Akpınar YE, Ünal ÖF, Yekeler E. Ectopic intrathyroidal thymus in children: Prevalence, imaging findings and evolution. Turk J Pediatr 2017; 59: 387-394. Read More

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http://www.turkishjournalpediatrics.org/doi.php?doi=10.24953
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http://dx.doi.org/10.24953/turkjped.2017.04.004DOI Listing
December 2018
7 Reads

Fatal Morvan Syndrome Associated With Myasthenia Gravis.

Neurologist 2017 Jan;22(1):29-33

Departments of *Neurology †Neuropathology ‡Neuro-Imaging and Interventional Radiology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.

Introduction: Morvan syndrome is a rare and complex autoimmune disorder affecting multiple sites of neuraxis.

Case Report: We present fulminant Morvan syndrome, developing on a background of chronic myasthenia gravis. A 54-year-old gentleman presented with fluctuating ophthalmoplegia and proximal muscles weakness of 7 years duration that remitted with pyridostigmine and prednisolone. Read More

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http://dx.doi.org/10.1097/NRL.0000000000000097DOI Listing
January 2017
9 Reads

Thymic Epidermoid Cyst: Clinical and Imaging Manifestations of This Rare Anterior Mediastinal Mass.

Case Rep Radiol 2016 24;2016:5789321. Epub 2016 Nov 24.

Department of Radiology, Allegheny Health Network, Pittsburgh, PA, USA.

Thymic epidermoid cysts are an extremely rare entity. These arise from epidermal cells that migrate to the thymus. The radiologic diagnosis of this rare lesion is challenging. Read More

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https://www.hindawi.com/journals/crira/2016/5789321/
Publisher Site
http://dx.doi.org/10.1155/2016/5789321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143738PMC
November 2016
8 Reads

Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study.

Diagn Interv Radiol 2017 Jan-Feb;23(1):10-14

Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.

Purpose: We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum.

Methods: In this study, 25 patients with an anterior mediastinal lesion underwent CT perfusion imaging from January 2015 to February 2016. Diagnoses included thymoma (n=7), thymic hyperplasia (n=8), lymphoma (n=4), thymic carcinoma (n=3), and invasive lung cancer (n=3). Read More

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http://dx.doi.org/10.5152/dir.2016.16093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214070PMC
May 2017
9 Reads

Ectopic Intrathyroidal Thymus in Childhood: A Sonographic Finding Leading to Misdiagnosis.

Horm Res Paediatr 2016 19;86(5):325-329. Epub 2016 Oct 19.

Division of Endocrinology, Growth and Development, 'P. & Α. Kyriakou' Children's Hospital, Athens, Greece.

Background: During gestation, the primordial thymus migrates from the pharynx to the anterior mediastinum, thus thymic tissue can remain at any point along this path. Intrathyroidal thymic remnants are rare, and their sonographic patterns have only recently been described. This retrospective study presents the sonographic appearance of ectopic intrathyroidal thymus and emphasizes the role of sonography in order to avoid misdiagnosis. Read More

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http://dx.doi.org/10.1159/000450724DOI Listing
April 2017
13 Reads

Value of volume-based early metabolic response in patients with unresectable thymic epithelial tumor.

Lung Cancer 2016 10 26;100:24-29. Epub 2016 Jul 26.

Departments of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: We conducted this study to investigate the value of early metabolic responses assessed by (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) in predicting prognosis and monitoring treatment response in patients with unresectable thymic epithelial tumors (TETs).

Patients And Methods: Study subjects were selected from the prospective dataset of a phase II clinical trial for cisplatin plus Cremorphor EL-free paclitaxel. A total of thirty patients with unresectable TETs who underwent baseline and early post treatment scan after two cycles of chemotherapy were enrolled (22 Male; mean age 55. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01695002163042
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http://dx.doi.org/10.1016/j.lungcan.2016.07.025DOI Listing
October 2016
8 Reads

Metastatic Thymic Carcinoma Presenting as a Posterior Fossa Mass: Case Report and Review of the Literature.

World Neurosurg 2016 Sep 12;93:486.e1-6. Epub 2016 Jul 12.

Department of Neurosurgery, University of Cincinnati College of Medicine, Brain Tumor Center at the University of Cincinnati Neuroscience Institute; and Mayfield Clinic, Cincinnati, Ohio, USA. Electronic address:

Background: Thymic epithelial tumors (TETs) are uncommon lesions, and cerebral metastases from these tumors are even rarer. We report a case of a posterior fossa metastasis in a patient with a known history of thymic carcinoma.

Case Description: A 47-year-old man with a history of Hodgkin lymphoma and thymic carcinoma presented with headache, nausea, and ataxia. Read More

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http://dx.doi.org/10.1016/j.wneu.2016.07.001DOI Listing
September 2016
9 Reads

[Thymic lesions: A 4 years-review].

Rev Port Cir Cardiotorac Vasc 2016 Jul-Dec;23(3-4):125-129

Serviço de Imagiologia do Centro Hospitalar de Vila Nova de Gaia/Espinho, Portugal.

Introduction: The difficulty in differentiating invasive from non-invasive thymic tumours solely by histological features, leads to the decision of resecting suspected lesions except in the presence of: (a) diffuse metastasis; or (b) typical imaging findings of thymic hyperplasia or after recovering from some recent stress. Therefore, the role of radiology is of the utmost importance in the initial evaluation and staging of thymic mediastinal masses.

Methods: The objective of this study was to elaborate a retrospective analysis of the cases of thymic lesions that underwent surgery at the Cardiothoracic Department of Centro Hospitalar Vila Nova de Gaia/Espinho (CHVNG/E), from January 2013 to December 2016, illustrating their main radiologic findings with computed tomography (CT) images. Read More

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December 2016
6 Reads

A Rare Case of Multilocular Thymic Cyst with Follicular Lymphoid Hyperplasia: Radiologic and Histopathologic Features.

Nucl Med Mol Imaging 2016 Jun 22;50(2):161-3. Epub 2016 Feb 22.

Department of pathology, Konyang University Hospital, Daejeon, Republic of Korea.

Multilocular thymic cysts are rare and acquired lesions induced by an inflammatory arising within the thymus. We report a rare case of multilocular thymic cyst with follicular lymphoid hyperplasia in a 59-year-old female. Chest CT and MRI revealed a large multilocular cystic mass, which contains thick septa and nodules in the thymus. Read More

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http://link.springer.com/10.1007/s13139-016-0404-2
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http://dx.doi.org/10.1007/s13139-016-0404-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870468PMC
June 2016
3 Reads

Recovery of pulmonary and skin lesions of sarcoidosis after thymectomy.

Acta Clin Belg 2016 Dec 26;71(6):441-443. Epub 2016 Apr 26.

a Faculty of Medicine, Department of Chest Diseases , Hacettepe University , Ankara , Turkey.

Objective And Importance: Sarcoidosis is a multisystem inflammatory disorder of unknown etiology. It is characterized by the presence of noncaseating granulomas and an inflammatory process in which T lymphocytes, especially type-1 helper T (Th1) cells, macrophages and different cytokines are involved. Different studies have shown the importance of genetic background in addition to environmental exposure in explaining different clinical phenotypes and disease outcome. Read More

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http://dx.doi.org/10.1080/17843286.2016.1152671DOI Listing
December 2016
5 Reads

Multiple endocrine neoplasia type 1 syndrome: single centre experience from western India.

Fam Cancer 2016 10;15(4):617-24

Department of Endocrinology, Seth G S Medical College, KEM Hospital, Parel, Mumbai, 400012, India.

Multiple endocrine neoplasia type 1 syndrome (MEN1) is a rare autosomal dominant familial cancer syndrome affecting multiple endocrine glands. Published literature on MEN1 from Indian subcontinent is scarce. We report here a case series of MEN1 patients (n = 18) from 14 unrelated families. Read More

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http://dx.doi.org/10.1007/s10689-016-9891-7DOI Listing
October 2016
11 Reads
1 Citation
1.620 Impact Factor

MRI-Guided Percutaneous Biopsy of Mediastinal Masses Using a Large Bore Magnet: Technical Feasibility.

Cardiovasc Intervent Radiol 2016 May 24;39(5):761-767. Epub 2015 Nov 24.

Department of Interventional Radiology, Nouvel Hôpital Civil, Strasbourg, France.

Objective: To evaluate the diagnostic accuracy and safety of magnetic resonance imaging (MRI)-guided percutaneous biopsy of mediastinal masses performed using a wide-bore high-field scanner.

Materials And Methods: This is a retrospective study of 16 consecutive patients (8 male, 8 female; mean age 74 years) who underwent MRI-guided core needle biopsy of a mediastinal mass between February 2010 and January 2014. Size and location of lesion, approach taken, time for needle placement, overall duration of procedure, and post-procedural complications were evaluated. Read More

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http://dx.doi.org/10.1007/s00270-015-1246-5DOI Listing
May 2016
2 Reads

First description of cervical intradural thymoma metastasis.

World J Clin Cases 2015 Nov;3(11):946-50

Nicola Marotta, Cristina Mancarella, Davide Colistra, Alessandro Landi, Demo Eugenio Dugoni, Roberto Delfini, Department of Neurology and Psychiatry, Division of Neurosurgery, University of Rome "Sapienza", 00161 Rome, Italy.

Thymoma and thymic carcinoma are rare epithelial tumors, which originate from the thymus gland. According to the World Health Organization there are "organotypic" (types A, AB, B1, B2, and B3) and "non-organotypic" (thymic carcinomas) thymomas. Type B3 thymomas are aggressive tumors, which can metastasize. Read More

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http://dx.doi.org/10.12998/wjcc.v3.i11.946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644897PMC
November 2015
2 Reads

Value of 18F-FDG PET/CT for Predicting the World Health Organization Malignant Grade of Thymic Epithelial Tumors: Focused in Volume-Dependent Parameters.

Clin Nucl Med 2016 Jan;41(1):15-20

From the *Department of Thoracic and Cardiovascular Surgery, Ajou University School of Medicine, Suwon; †Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul; ‡Department of Thoracic and Cardiovascular Surgery, National Health Insurance Service Ilsan Hospital, Gyeonggi; and §Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.

Purpose: We investigated whether preoperative parameters of 18F-FDG PET/CT were correlated with the World Health Organization (WHO) classification and/or Masaoka staging of thymic epithelial tumors.

Patients And Methods: We reviewed 61 patients retrospectively who were diagnosed with thymic epithelial tumors after surgical resection and PET/CT. A volume of interest was drawn on the primary lesion, using an SUV cutoff of 2. Read More

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http://dx.doi.org/10.1097/RLU.0000000000001032DOI Listing
January 2016
12 Reads

Unusual diagnosis of a solitary thyroid nodule in the paediatric population: cervical thymic cyst.

BMJ Case Rep 2015 Sep 29;2015. Epub 2015 Sep 29.

Department of Pathology, Vijaya Group of Hospitals, Chennai, Tamil Nadu, India.

We present a case of an 8-year-old girl with a painless swelling in her neck. An ultrasonogram revealed a cystic nodule with internal echoes, lying posterior to right lobe of thyroid, and MRI confirmed it. Thyroid scintigraphy did not show any uptake in the swelling. Read More

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http://dx.doi.org/10.1136/bcr-2015-212186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593288PMC
September 2015
1 Read

Diagnostic Yield of CT-Guided Percutaneous Transthoracic Needle Biopsy for Diagnosis of Anterior Mediastinal Masses.

AJR Am J Roentgenol 2015 Oct;205(4):774-9

1 Department of Radiology, Massachusetts General Hospital, 55 Fruit St, FND 202, Boston, MA 02114.

Objective: The purpose of this study was to evaluate the diagnostic yield and accuracy of CT-guided percutaneous biopsy of anterior mediastinal masses and assess prebiopsy characteristics that may help to select patients with the highest diagnostic yield.

Materials And Methods: Retrospective review of all CT-guided percutaneous biopsies of the anterior mediastinum conducted at our institution from January 2003 through December 2012 was performed to collect data regarding patient demographics, imaging characteristics of biopsied masses, presence of complications, and subsequent surgical intervention or medical treatment (or both). Cytology, core biopsy pathology, and surgical pathology results were recorded. Read More

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http://dx.doi.org/10.2214/AJR.15.14442DOI Listing
October 2015
8 Reads

[A Case of Infantile Cervical Ectopic Thymus].

Nihon Jibiinkoka Gakkai Kaiho 2015 May;118(5):662-7

We report herein on a case of ectopic cervical thymus in a 5-year-old boy and the literature is reviewed. Swelling of the right neck was seen in the patient in his newborn period and it was diagnosed as cystic disease of the neck in a previous hospital at 4 months of age. Ultrasonography (US) and MRI revealed a cervical tumor consisting of a solid component in our hospital, and histopathologic examination showed no evidence of malignancy. Read More

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May 2015
6 Reads

Initial Experience of 18F-FDG PET/MRI in Thymic Epithelial Tumors: Morphologic, Functional, and Metabolic Biomarkers.

Clin Nucl Med 2016 Jan;41(1):8-14

From the *Department of Radiology, †Biomedical Research Institute, Departments of ‡Thoracic and Cardiovascular Surgery, §Nuclear Medicine, and ∥Pathology, Pusan National University Hospital, Busan, South Korea; and ¶Department of Radiology, University of Colorado School of Medicine, Aurora, CO.

Purpose: The aim of this study was to investigate the value of morphologic, functional, and metabolic biomarkers acquired concurrently at PET/MRI in patients with thymic epithelial tumors.

Patients And Methods: During 1 year, 9 patients with suspected thymic epithelial tumors at contrast-enhanced chest CT were prospectively enrolled and underwent preoperative 18F-FDG PET/MRI. Two chest radiologists prospectively reviewed the CT and MRI scans of PET/MRI in consensus, and 2 nuclear physicians reviewed the PET images. Read More

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http://dx.doi.org/10.1097/RLU.0000000000000946DOI Listing
January 2016
5 Reads

Primary thymic cholesteroloma: a clinicopathological correlation of four cases of an unusual benign lesion.

Virchows Arch 2015 Nov 13;467(5):609-11. Epub 2015 Aug 13.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Four cases of an unusual thymic lesion characterized by the presence of extensive cholesterol cleft granulomata are presented. The patients were four men between the ages of 58 and 71 years (average 64.5 years). Read More

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http://link.springer.com/content/pdf/10.1007/s00428-015-1822
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http://dx.doi.org/10.1007/s00428-015-1822-8DOI Listing
November 2015
2 Reads

Thymic lymphoid hyperplasia with multilocular thymic cysts diagnosed before the Sjögren syndrome diagnosis.

Diagn Pathol 2015 Jul 16;10:103. Epub 2015 Jul 16.

Department of Ophthalmology, Kanazawa Medical University, Uchinada, Ishikawa, Japan.

Background: Thymic lymphoid hyperplasia is often present with myasthenia gravis as well as other autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Of the 4 cases of thymic lymphoid hyperplasia associated with Sjögren syndrome that have been reported, no case with a thymic lesion diagnosis that led to the diagnosis of Sjögren syndrome has been reported. We herein report a case of thymic lymphoid hyperplasia with multilocular thymic cysts, diagnosed before Sjögren syndrome. Read More

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http://dx.doi.org/10.1186/s13000-015-0332-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502560PMC
July 2015
8 Reads

Utility of baseline 18FDG-PET/CT functional parameters in defining prognosis of primary mediastinal (thymic) large B-cell lymphoma.

Blood 2015 Aug 18;126(8):950-6. Epub 2015 Jun 18.

Oncology Institute of Southern Switzerland, Bellinzona, Switzerland;

The International Extranodal Lymphoma Study Group (IELSG) 26 study was designed to evaluate the role of (18)F-fluorodeoxyglucose (18FDG) positron emission tomography/computed tomography (PET/CT) in the management of primary mediastinal (thymic) large B-cell lymphoma (PMBCL). We examined the prognostic impact of functional PET parameters at diagnosis. Metabolic activity defined by the maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) was measured on baseline 18FDG PET/CT following a standard protocol in a prospectively enrolled cohort of 103 PMBCL patients. Read More

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http://dx.doi.org/10.1182/blood-2014-12-616474DOI Listing
August 2015
29 Reads

Ectopic Pleural Thymoma : Report of a case.

Acta Chir Belg 2014 Sep-Oct;114(5):358-61

Departments of Surgery, AZ Sint-Elizabeth, Zottegem, Belgium.

Thymomas are uncommon neoplasms that account for 50% of all masses in the anterior mediastinum. Medial sternotomy is the typical approach for resection. We report a case of an ectopic thymoma within the right pleural cavity in a 76-year old Caucasian women. Read More

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January 2018
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A rare case of primary thymic adenocarcinoma mimicking small cell lung cancer.

Tuberc Respir Dis (Seoul) 2015 Apr 2;78(2):112-9. Epub 2015 Apr 2.

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Primary thymic adenocarcinoma is a very rare malignancy of the anterior mediastinum with no standardized treatment. A 36-year-old male patient presented with hoarseness over the past 3 months. A chest computed tomography (CT) scan showed an infiltrative mass to the proximal vessels and aortic arch in left upper mediastinum (4. Read More

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http://dx.doi.org/10.4046/trd.2015.78.2.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388894PMC
April 2015
3 Reads

DiGeorge syndrome who developed lymphoproliferative mediastinal mass.

Korean J Pediatr 2015 Mar 20;58(3):108-11. Epub 2015 Mar 20.

Department of Pediatrics, Yonsei University College of Medicine, Severance Children's Hospital, Seoul, Korea.

DiGeorge syndrome is an immunodeficient disease associated with abnormal development of 3rd and 4th pharyngeal pouches. As a hemizygous deletion of chromosome 22q11.2 occurs, various clinical phenotypes are shown with a broad spectrum. Read More

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http://dx.doi.org/10.3345/kjp.2015.58.3.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388972PMC
March 2015
4 Reads

Ectopic ACTH syndrome caused by desmopressin-responsive thymic neuroendocrine tumor.

Endocr J 2015 29;62(5):441-7. Epub 2015 Mar 29.

Division of Endocrinology and Diabetology, Ohme Municipal General Hospital, Ohme 198-0042, Japan.

A 32-year-old Chinese woman with rapid weight gain and progressive edema was found to have typical Cushingoid features. Her endocrine data were consistent with a diagnosis of ACTH-dependent Cushing's syndrome. To differentiate ectopic ACTH syndrome (EAS) from Cushing's disease (CD), various dynamic endocrine and imaging tests were performed. Read More

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http://dx.doi.org/10.1507/endocrj.EJ14-0455DOI Listing
February 2016
4 Reads

MEN1 disease occurring before 21 years old: a 160-patient cohort study from the Groupe d'étude des Tumeurs Endocrines.

J Clin Endocrinol Metab 2015 Apr 16;100(4):1568-77. Epub 2015 Jan 16.

Centre Hospitalier Universitaire de Dijon (P.G.), Endocrine Surgery, Dijon, France; INSERM U866, Dijon, France; University of Burgundy, Dijon, France; Service d'Endocrinologie et Maladies Métaboliques (A.D., N.L-B.), Centre Hospitalier Universitaire, Hôpital Robert Debré, Reims, France, Clinique d'Endocrinologie (M.L.), Centre Hospitalier Universitaire, Nantes, France; Service de Médecine Interne et Endocrinologie (C.C-B.), Clinique Marc Linquette, Centre Hospitalier Régional et Universitaire, Lille, France; Service d'Oncologie Médicale (P.N.), Institut Paoli-Calmettes, APHM, Université Aix-Marseille, Marseille, France; Service d'Endocrinologie (H.dB.), Centre Hospitalier de Chambéry, Chambéry, France; Département d'Endocrinologie (X.B.), Hôpital Cochin, Université Paris Descartes, Paris, France; Service de Gastroentérologie-Pancréatologie (P.R.), APHP, Hôpital Beaujon et Université Paris 7 Denis Diderot, Clichy, France; Fédération d'Endocrinologie (F.B-C.), Hospice Civils de Lyon et Université Lyon 1, Groupement Hospitalier Est. Lyon, France; Service d'Endocrinologie (B.V.), Diabète et Maladies Métaboliques, Centre Hospitalier Universitaire de Dijon, Hôpital du Bocage, Dijon, France; Département d'Endocrinologie (J.L.S.), Hopital de l'Archet, Nice, France; Service de Chirurgie Générale (F.M.), Viscérale et Endocrinienne, Groupement Hospitalier Universitaire Est, Hôpital de la Pitié, Paris, France; Service d'Endocrinologie (A.T.), Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France; Département d'Endocrinologie (J.M.K.), Hôpital Universitaire de Rouen. Rouen, France; Service d'Endocrinologie (P.dA.), Centre Hospitalier d'Avignon, Avignon, France; Service d'Endocrinologie (O.C.), Diabète et Maladies Métaboliques, Centre Hospitalier Universitaire de Grenoble, Hôpital Michalon, Grenoble, France; Service d'Endocrinologie (S.C-M.), Centre Hôpitalier Universitaire. Hôpital St-Antoine, Paris, France; Service d'Hép

Context: Multiple endocrine neoplasia Type-1 (MEN1) in young patients is only described by case reports.

Objective: To improve the knowledge of MEN1 natural history before 21 years old.

Methods: Obtain a description of the first symptoms occurring before 21 years old (clinical symptoms, biological or imaging abnormalities), surgical outcomes related to MEN1 Neuro Endocrine Tumors (NETs) occurring in a group of 160 patients extracted from the "Groupe d'étude des Tumeurs Endocrines" MEN1 cohort. Read More

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http://dx.doi.org/10.1210/jc.2014-3659DOI Listing
April 2015
2 Reads

Correlative Imaging in a Patient with Cystic Thymoma: CT, MR and PET/CT Comparison.

Pol J Radiol 2015 13;80:22-6. Epub 2015 Jan 13.

Department of Diagnostic Imaging, University Federico II, Fondazione SDN (IRCCS), Naples, Italy.

Background: Cystic thymoma is a rare variant of thymic neoplasm characterized by almost complete cystic degeneration with mixed internal structure. We describe a case of a 60 year-old woman with a cystic thymoma studied with advanced tomographic imaging stydies. CT, MRI and PET/CT with (18)F-FDG were performed; volumetric CT and MRI images provided better anatomic evaluation for pre-operative assessment, while PET/CT was helpful for lesion characterization based on (18)F-FDG uptake. Read More

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http://dx.doi.org/10.12659/PJR.892105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294593PMC
January 2015
4 Reads