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    1049 results match your criteria Thrombophlebitis Superficial

    1 OF 21

    [Superficial venous thrombosis. A state of art].
    Orv Hetil 2017 Jan;158(4):129-138
    II. Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Kútvölgyi út 4., 1125.
    For a long time superficial thrombophlebitis has been thought to be a rather benign condition. Recently, when duplex ultrasound technique is used for the diagnosis more and more often, the disease is proved to be more dangerous than anticipated. Thrombosis propagates to the deep veins in 6-44% and pulmonary embolism was observed on the patients in 1,5-33%. Read More

    The Effectiveness of Diclofenac Sodium in the Treatment of Mondor's Disease of the Breast: The Topical Patch Compared to the Oral Capsules.
    Breast J 2017 Jan 12. Epub 2017 Jan 12.
    Department of Pharmacy, Al Ansar General Hospital, Medina, Saudi Arabia.
    Mondor's disease of the breast is a rare, benign sclerosing superficial thrombophlebitis of the subcutaneous veins of the anterior or lateral chest wall, which is treated conservatively. We aim in this study to evaluate the outcome and effectiveness of our treatment protocol using oral diclofenac sodium and topical diclofenac sodium patch in 172 patients. A retrospective database analysis of 172 female patients between January 2001 and December 2010 was done. Read More

    Randomized trial of radiofrequency ablation versus conventional surgery for superficial venous insufficiency: if you don't tell, they won't know.
    Clinics (Sao Paulo) 2016 Nov 1;71(11):650-656. Epub 2016 Nov 1.
    Hospital Israelita Albert Einstein, Division of Vascular and Endovascular Surgery, São Paulo/SP, Brazil.
    Objectives:: This study compared radiofrequency ablation versus conventional surgery in patients who had not undergone previous treatment for bilateral great saphenous vein insufficiency, with each patient serving as his own control.

    Method:: This was a randomized controlled trial that included 18 patients and was carried out between November 2013 and May 2015. Each of the lower limbs of each patient was randomly assigned to undergo either radiofrequency ablation or conventional surgery. Read More

    Predicting and preventing thromboembolic events in patients receiving cisplatin-based chemotherapy for germ cell tumours.
    Eur J Cancer 2016 Dec 4;69:151-157. Epub 2016 Nov 4.
    Department of Cancer Medicine, Institut Gustave Roussy, Université Paris-Sud, 94800 Villejuif, France. Electronic address:
    Background: Patients with germ cell tumours (GCT) receiving cisplatin-based chemotherapy are at high risk of thromboembolic events (TEE). Previously, we identified serum lactate dehydrogenase (LDH) and body surface area (BSA) as independent predictive factors for TEE. The aim of this study was to validate these predictive factors and to assess the impact of thromboembolism prophylaxis in patients at risk of deep venous thrombosis (DVT). Read More

    Bodybuilding-induced Mondor's disease of the chest wall.
    Phys Ther Sport 2017 Jan 4;23:133-135. Epub 2016 Sep 4.
    Department of Internal Medicine, Central Hospital of Bolzano|Bozen, Lorenz-Böhler-Street 5, 39100, Bolzano|Bozen (BZ), Italy. Electronic address:
    Objective: To describe the association of bodybuilding abdominal exercise with the development of superficial sclerosing thrombophlebitis of the anterolateral thoracoabdominal wall.

    Design: A single case study.

    Setting: University-affiliated regional community hospital. Read More

    Evaluating the Potential of Routine Blood Tests to Identify the Risk of Deep Vein Thrombosis: A 1-Year Monocenter Cohort Study.
    Angiology 2016 Oct 20. Epub 2016 Oct 20.
    Department of Medical, Surgical Sciences and Advanced Technologies, G.F. Ingrassia, University of Catania, Catania, Italy.
    Study on 295 consecutive medical patients to evaluate the potential of routine blood tests to identify the risk of deep vein thrombosis (DVT). The tests included in a DVT risk stratification model system were erythrocyte sedimentation rate, antithrombin III, C-reactive protein, D-dimer, and N-terminal pro-brain natriuretic peptide. The DVT risk stratification system was moderately prognostic (area under the curve: 0. Read More

    Initial management and outcomes after superficial thrombophlebitis: The Cardiovascular Research Network Venous Thromboembolism study.
    J Hosp Med 2016 Jun 1;11(6):432-4. Epub 2016 Feb 1.
    Division of Hospital Medicine, University of California, San Francisco, San Francisco, California.
    Although superficial thrombophlebitis (SVTE) is generally considered a benign, self-limited disease, accumulating evidence suggests that it often leads to more serious forms of venous thromboembolism. We reviewed the medical charts of 329 subjects with SVTE from the Cardiovascular Research Network Venous Thromboembolism cohort study to collect information on the acute treatment of SVTE and subsequent diagnosis of deep venous thrombosis within 1 year. All participants received care within Kaiser Permanente Northern California, a large, integrated healthcare delivery system. Read More

    Behçet's pulmonary artery aneurysms treated with infliximab and monitored with the 6-min walk test.
    Oxf Med Case Reports 2016 Apr 26;2016(4):94-6. Epub 2016 Apr 26.
    Department of Rheumatology , Norfolk and Norwich University Hospital , Norfolk , UK.
    Pulmonary involvement in Behçet's disease (BD) is uncommon; however, it is potentially fatal due to the risk of massive haemoptysis. We describe the case of a 36-year-old male presenting with a 2-month history of worsening dyspnoea, weight loss, haemoptysis, oral ulceration, erythema nodosum and superficial thrombophlebitis. He was diagnosed with pulmonary vasculitis secondary to BD; however, his symptoms were refractory to initial treatment with cyclophosphamide, azathioprine and prednisolone. Read More

    Prevalence of Isolated Asymptomatic Deep Vein Thrombosis in Varicose Vein Patients with Superficial Thrombophlebitis: A Single Center Experience in Japan.
    Ann Vasc Dis 2016 31;9(1):2-7. Epub 2015 Dec 31.
    Department of Vascular Surgery, Teikyo University, Tokyo, Japan.
    Objective: Prevalence of asymptomatic deep vein thrombosis (DVT) in patients with primary varicose veins remains unclear.

    Materials And Methods: Here, we conducted a retrospective study to clarify the incidence of asymptomatic DVT in patients with varicose veins, especially focusing on those with superficial thrombophlebitis (STP).

    Results: Among 431 patients with primary varicose veins with saphenous vein incompetence, 20 (4. Read More

    Postoperative Massive Pulmonary Embolism Due to Superficial Vein Thrombosis of the Upper Limb.
    J Clin Med Res 2016 Apr 27;8(4):338-41. Epub 2016 Feb 27.
    Division of Anesthesiology, Department of Anesthesiology, Endoscopy and Cardiology, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy.
    It is well known that deep vein thrombosis of the upper extremities is linked to high morbidity/mortality, resulting in 12-20% of all documented pulmonary embolism; however, there are few data about thromboembolism originating from a vein and/or a branch of a superficial vein of the upper extremities. Pulmonary embolism secondary to upper limb superficial vein thrombosis (not combined with upper extremities deep vein thrombosis) is a very rare clinical manifestation with few cases reported in the literature. We report a rare case of thrombophlebitis in departure from a superficial branch of the cephalic vein of the right arm, complicated by cardiac arrest secondary to a massive pulmonary embolism in a patient who underwent major surgery for ovarian cancer. Read More

    Superficial vein thrombosis treated for 45 days with rivaroxaban versus fondaparinux: rationale and design of the SURPRISE trial.
    J Thromb Thrombolysis 2016 Aug;42(2):197-204
    Center for Vascular Medicine and Department of Medicine III, Division of Angiology, University Hospital "Carl Gustav Carus", Technical University Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
    Patients with superficial vein thrombosis (SVT) are commonly treated with low-molecular weight heparin or fondaparinux in prophylactic, intermediate or therapeutic dosages for treatment periods of 10-45 days. This practice is also reflected by the current guideline recommendations. However, given the broad range of thromboembolic complication rates in SVT (between 0 and 30 % have been reported) it seems reasonable to suspect that risk stratification is needed to differentiate patients at low risk who may not benefit from anticoagulation from those at high risk who may need higher dosages or a longer duration of anticoagulation. Read More

    [Mondor's disease of penis: A case report].
    Rev Med Interne 2016 Sep 10;37(9):636-8. Epub 2016 Mar 10.
    Service d'urologie, clinique Porte-Océane, 4, rue Jacques-Monod, 85101 Les Sables-d'Olonne, France.
    Introduction: Mondor's disease is a rare superficial thrombophlebitis, historically involving the thoracic venous system of women. However, it can occur in both gender and all over the skin.

    Case Report: We report a 40-year-old man with type one diabetes who presented with a thrombosis of the superficial dorsal vein of the penis that he treated as a fungal infection. Read More

    A multicenter, randomized, placebo-controlled trial of endovenous thermal ablation with or without polidocanol endovenous microfoam treatment in patients with great saphenous vein incompetence and visible varicosities.
    Phlebology 2016 Mar 7. Epub 2016 Mar 7.
    Division of Vascular Surgery, Stony Brook School of Medicine, Stony Brook, NY, USA Stony Brook Vein Center, Manhasset, NY, USA.
    Objectives: *Varithena 017 Investigator Group: Michael Vasquez, MD, Venous Institute of Buffalo, Amherst, NY; Antonios Gasparis, MD, Stony Brook University Medical Center, Stony Brook, NY; Kathleen Gibson, MD, Lake Washington Vascular, Bellevue, WA; James Theodore King, MD, Vein Clinics of America, Oakbrook Terrace, IL; Nick Morrison, MD, Morrison Vein Institute, Scottsdale, AZ; Girish Munavalli, MD, Dermatology, Laser & Vein Specialists of the Carolinas, Charlotte, NC; Eulogio J. Sanchez, MD, Batey Cardiovascular Center, Bradenton, FL. Varithena® is a trademark of Provensis Ltd, a BTG International group company. Read More

    Doppler Ultrasound and Magnetic Resonance Imaging Findings of Penile Mondor's Disease: Case Report and Literature Review.
    Pol J Radiol 2016 2;81:36-8. Epub 2016 Feb 2.
    Department of Radiology, Gazi University Medical School, Ankara, Turkey.
    Background: Penile involvement is a rare, self-limiting, benign genital condition. In Mondor's disease the underlying pathology is thrombophlebitis of a superficial vein.

    Case Report: In this case report, we want to present a rare Penile Mondor's disease with literature review. Read More

    Prevalence of deep vein thrombosis and pulmonary embolism in patients with superficial vein thrombosis: a systematic review and meta-analysis.
    J Thromb Haemost 2016 May 15;14(5):964-72. Epub 2016 Mar 15.
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.
    Unlabelled: Essentials The association of superficial vein thrombosis (SVT) with venous thromboembolism (VTE) is variable. We performed a meta-analysis to assess the prevalence of concomitant VTE in patients with SVT. Deep vein thrombosis was found in 18. Read More

    Low-level laser therapy for the treatment of superficial thrombophlebitis after chemotherapy in breast cancer patients: a case study.
    J Phys Ther Sci 2015 Dec 28;27(12):3937-8. Epub 2015 Dec 28.
    Department of Physical Therapy, Shinsung University: 1 Daehack-ro, Jeongmi-myeon, Dangjin-si, Chungcheongnam-do, Republic of Korea.
    [Purpose] We report the case of a breast cancer patient with superficial thrombophlebitis treated with low-level laser therapy. [Case] The patient was a 66-year-old women who developed superficial thrombophlebitis in the left upper limb after chemotherapy. She was administered 6 sessions of low-level laser therapy. Read More

    Abdominal Mondor disease mimicking acute appendicitis.
    Int J Surg Case Rep 2016 13;20:37-40. Epub 2016 Jan 13.
    Division of General Surgery, Etablissement Hospitalier du Nord Vaudois, Yverdon-les-Bains, Switzerland. Electronic address:
    Introduction: Mondor disease (MD), a superficial thrombophlebitis of the thoraco-epigastric veins and their confluents is rarely reported in the literature. The superior epigastric vein is the most affected vessel but involvement of the inferior epigastric vessels or their branches have also been described. There is no universal consensus on treatment in the literature but most authors suggest symptomatic treatment with non-steroid anti-inflammatory drugs (NSAIDs). Read More

    The Damage of Penile Doppler Ultrasonoghraphy in Diagnosis of Penile Mondor's Disease: A Report of Two Cases.
    Urol Case Rep 2015 Mar 17;3(2):42-3. Epub 2015 Jan 17.
    Adiyaman University, Faculty of Medicine, Department of Urology, Adiyaman, Turkey.
    Penile Mondor's disease is a thrombophlebitis of the superficial dorsal vein of the penis. It is a rare clinical diagnosis and generally resolves spontaneously. A simple physical examination is sufficient for diagnosis but color Doppler ultrasonography is often carried out as a further investigation. Read More

    Treatment for superficial infusion thrombophlebitis of the upper extremity.
    Cochrane Database Syst Rev 2015 Nov 20(11):CD011015. Epub 2015 Nov 20.
    Department of Medical, Oral and Biotechnological Sciences, University "G. D'Annunzio" of Chieti-Pescara, via dei Vestini 31, Chieti, Italy, 66013.
    Background: Although superficial thrombophlebitis of the upper extremity represents a frequent complication of intravenous catheters inserted into the peripheral veins of the forearm or hand, no consensus exists on the optimal management of this condition in clinical practice.

    Objectives: To summarise the evidence from randomised clinical trials (RCTs) concerning the efficacy and safety of (topical, oral or parenteral) medical therapy of superficial thrombophlebitis of the upper extremity.

    Search Methods: The Cochrane Vascular Group Trials Search Co-ordinator searched the Specialised Register (last searched April 2015) and the Cochrane Register of Studies (2015, Issue 3). Read More

    Does cryostripping add anything to the treatment of the ascending thrombophlebitis of the great saphenous vein?
    Vascular 2016 Oct 5;24(5):510-4. Epub 2015 Nov 5.
    Department of Surgery, Kanizsai Dorottya Hospital, Hungary.
    Objective: To analyse the differences of outcome between cryostripping and conservative therapy in the treatment of superficial vein thrombosis.

    Patients And Methods: A retrospective analysis was performed between the October of 2001 and the October of 2014. In all, 246 cases were eligible for the study. Read More

    Patients' experiences of living with varicose veins and management of the disease in daily life.
    J Clin Nurs 2016 Mar 28;25(5-6):733-41. Epub 2015 Oct 28.
    Department of Care Science, Faculty of Health and Society, Malmö University, Malmö, Sweden.
    Aims And Objectives: The aim was to describe the experience of living with varicose veins classified according CEAP (clinical class, aetiology, anatomy, pathophysiology) as C4 (eczema or thrombophlebitis) and management of the disease in daily life.

    Background: Primary chronic venous insufficiencies with varicose veins are a relatively common condition among both men and women. Several studies have shown that quality of life improved after treatment of varicose veins compared to before treatment. Read More

    Persistent serpentine supravenous hyperpigmented eruption in lepromatous leprosy after minocycline.
    Lepr Rev 2015 Jun;86(2):191-4
    Persistent serpentine supravenous hyperpigmented eruption (PSSHE) is a peculiar patterned eruption characterised by hyperpigmented streaks following the superficial venous network on the skin. Unlike the superficial thrombophlebitis, it is characterised by underlying vessels that are patent. It has been described most commonly after injection of chemotherapeutic drugs. Read More

    Toe Amputation After Minor Surgery in a Patient with Behçet's Disease: A Case Report.
    J Foot Ankle Surg 2016 May-Jun;55(3):638-41. Epub 2015 Oct 21.
    Associate Professor, Department of Plastic, Aesthetic and Reconstructive Surgery, Dicle University Medical School, Diyarbakir, Turkey.
    Behçet's disease is a systemic autoimmune vasculitis. Although various clinical findings can be observed depending on the pathologic features caused by the blood vessels involved, the classic triad of the disease includes oral aphthae, genital ulcers, and uveitis. Although complications involving the aorta or the vena cava inferior can prove fatal, thrombophlebitis in the superficial veins of the lower extremities are more commonly observed. Read More

    Seasonal variation in the superficial vein thrombosis frequency.
    Thromb Res 2015 Dec 8;136(6):1116-9. Epub 2015 Oct 8.
    CIC-EC Inserm, CIE3, CHU Hôpital Nord, Saint-Etienne, France; EA3065, Université Jean Monnet, PRES de Lyon, Saint-Etienne, France; Service de Médecine Vasculaire et Thérapeutique, CHU de Saint-Etienne, Saint-Etienne, France.
    Introduction: A seasonal variation of venous thromboembolic disease frequency is subject to discussion, and has been recently suggested for superficial vein thrombosis (SVT) in a small retrospective study. Our aim was to search for a seasonal variation of SVT frequency according to the data of larger studies.

    Materials And Methods: We analyzed the data of three French prospective multicenter studies with different designs which have included patients with SVT (STENOX, POST, and STEPH studies). Read More

    ULTRASOUND GUIDED FOAM SCLEROTHERAPY - THE SIMPLEST, LEAST INVASIVE, AND CHEAPEST METHOD FOR VARICOSE VEIN TREATMENT.
    Acta Clin Croat 2015 Jun;54(2):136-42
    The aim is to present our experience and observations regarding varicose vein treatment by means of ultrasound guided foam sclerotherapy (UGFS). The study included 81 patients, 54 with insufficient main stem superficial veins in one limb and 27 with both limbs affected. Great saphenous vein insufficiency was diagnosed in 68, small saphenous insufficiency in 18, anterior accessory saphenous vein insufficiency in 11, and Giacomini vein insufficiency in 3 limbs. Read More

    Outcomes associated with ablation compared to combined ablation and transilluminated powered phlebectomy in the treatment of venous varicosities.
    Phlebology 2016 Oct 15;31(9):618-24. Epub 2015 Sep 15.
    University of Michigan, Ann Arbor, MI, USA.
    Background: Patients with painful varicose veins and venous insufficiency can be treated by eliminating axial reflux only or by eliminating axial reflux plus phlebectomy with transilluminated powered phlebectomy. This study was undertaken with the aim of determining and improving signs and symptoms of venous disease (measured by venous clinical severity score) and complications (by routine surveillance ultrasound and long-term post-operative follow up) for each treatment strategy.

    Methods: We performed a retrospective evaluation of prospectively collected data from 979 limbs undergoing procedures for significant varicose veins and venous insufficiency from March 2008 until June 2014 performed at a single tertiary referral hospital. Read More

    Thrombophlebitis of the temporal vein as an extracranial complication of acute bacterial rhinosinusitis.
    Ear Nose Throat J 2015 Aug;94(8):E48-51
    Department of Otolaryngology-Head and Neck Surgery, Bern University Hospital, Inselspital, Universitätsklinik für Hals-, Nasen- und Ohrenkrankheiten, Kopf- und Halschirurgie, CH - 3010 Bern, Switzerland.
    A 39-year-old white man presented with a swollen left upper eyelid secondary to progressive acute bacterial rhinosinusitis (ABRS). Physical examination found a 40% reduction in vision in the left eye and right-sided erythematous temporal swelling with tenderness to palpation. Computed tomography revealed the presence of an inflammatory lesion in the left orbit. Read More

    Grave Complication of Pharyngitis: Lemierre syndrome.
    J Clin Diagn Res 2015 Jun 1;9(6):TD03-4. Epub 2015 Jun 1.
    Professor, Department of Radiology, S.S.G. Hospital, Medical College , Vadodara, India .
    Fusobacterium necrophorum is the causative agent in the pharyngitis. After invasion of the oropharyngeal mucosa by the organism leads to the development of the grave complications like superficial thrombophlebitis of internal jugular vein, septic emboli in the lung and coagulopathy. A 23-year-old male presented with chief complaints of sore throat, headache and high grade fever with past history of upper respiratory tract infection one month ago. Read More

    Predictors of venous thromboembolism recurrence, adjusted for treatments and interim exposures: a population-based case-cohort study.
    Thromb Res 2015 Aug 24;136(2):298-307. Epub 2015 Jun 24.
    Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
    Background: Predictors of venous thromboembolism (VTE) recurrence are uncertain.

    Objective: To identify predictors of VTE recurrence, adjusted for treatments and interim exposures.

    Materials And Methods: Using Rochester Epidemiology Project resources, all Olmsted County, MN residents with objectively-diagnosed incident VTE over the 13-year period, 1988-2000, who survived ≥1day were followed for first objectively-diagnosed VTE recurrence. Read More

    Antiphospholipid-mediated thrombosis: interplay between type of antibodies and localisation of lung, and cardiovascular incidences in primary antiphospholipid syndrome.
    Clin Exp Rheumatol 2015 Jul-Aug;33(4):531-6. Epub 2015 Jun 19.
    Medical Faculty, University of Belgrade, and Clinic for Pulmonology, Clinical Center of Serbia, Belgrade, Serbia.
    Objectives: The aim of this study was to analyse prevalence and type of pulmonary manifestations in patients with primary antiphospholipid syndrome (PAPS), their association to antiphospholipid antibody (aPL) type and localisation of peripheral vascular thrombosis, and possible relationship to existing cardiac manifestations.

    Methods: Our cross-sectional study comprised 318 PAPS patients, enrolled in the study as the Serbian APS Registry. aPL analysis included detection of aCL (IgG/IgM), ß2GPI (IgG/IgM) and LA, served to evaluate associations with cardiac and pulmonary manifestations. Read More

    Evaluation and Treatment of Penile Thrombophlebitis (Mondor's Disease).
    Curr Urol Rep 2015 Jun;16(6):39
    Department of Urology, Morsani College of Medicine, University of South Florida, 2 Tampa General Cir, STC6, Tampa, FL, 33606, USA,
    Superficial penile thrombophlebitis or penile Mondor's disease (PMD) is an underreported condition that causes anxiety and embarrassment in affected men. Patients usually present with a smooth, cord-like induration on the dorsal penile shaft 1-7 days after prolonged or intensive sexual intercourse, but other presentations of disease and triggers for endothelial damage are possible. The condition is typically self-limited with expected spontaneous resolution within 4-8 weeks of initial presentation, and absolute diagnosis is usually not necessary with management including supportive care and pain control. Read More

    Superficial Vein Thrombophlebitis in a Football Athlete.
    Clin J Sport Med 2016 Mar;26(2):e8-9
    Department of Family Medicine, The University of Iowa, Iowa City, Iowa.
    A 22-year-old professional football player presented to a preparticipation physical examination with a 2-week history of left leg discomfort extending from the groin to the knee over the previous 2 weeks. He was found to have superficial vein thrombophlebitis (SVT) of the left great saphenous vein extending from the knee to within approximately 1.6 cm of the saphenofemoral junction. Read More

    Mondor's disease in a patient after a mammotome biopsy.
    Wideochir Inne Tech Maloinwazyjne 2015 Apr 10;10(1):138-40. Epub 2015 Feb 10.
    First Chair of General, Oncological, and Gastrointestinal Surgery, Jagiellonian University Medical College, Krakow, Poland.
    Mondor's disease is a rare, benign condition characterised by thrombophlebitis affecting subcutaneous veins of the chest and/or abdomen without an accompanying inflammatory response. The disease has a multifactorial etiology and its course is benign. It is usually self-limiting or it is eliminated by local treatment. Read More

    Penile Mondor's Disease: Primum Non Nocere!
    Urol J 2015 Apr 29;12(2):2096-8. Epub 2015 Apr 29.
    Department of Radiology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey.
    Purpose: Penile Mondor’s disease (superficial thrombophlebitis of the dorsal vein of the penis) is a rare clinical diagnosis. It is an easily diagnosed and treated disease. Nevertheless, when reviewing the literature, we considered that unnecessary tests are carried out for diagnosis. Read More

    Human placenta-derived cells (PDA-001) for the treatment of adults with multiple sclerosis: a randomized, placebo-controlled, multiple-dose study.
    Mult Scler Relat Disord 2014 Nov 29;3(6):696-704. Epub 2014 Aug 29.
    Celgene Cellular Therapeutics, 7 Powderhorn Road, Warren, NJ 07059, United States. Electronic address:
    Background: Infusion of PDA-001, a preparation of mesenchymal-like cells derived from full-term human placenta, is a new approach in the treatment of patients with multiple sclerosis.

    Objective: This safety study aimed to rule out the possibility of paradoxical exacerbation of disease activity by PDA-001 in patients with multiple sclerosis.

    Methods: This was a phase 1b, multicenter, randomized, double-blind, placebo-controlled, 2-dose ranging study including patients with relapsing-remitting multiple sclerosis or secondary progressive multiple sclerosis. Read More

    [NHG guideline 'Deep-vein thrombosis and pulmonary embolus'].
    Ned Tijdschr Geneeskd 2015 ;159:A8657
    Nederlands Huisartsen Genootschap, afd. Richtlijnontwikkeling en Wetenschap, Utrecht.
    The revised Dutch College of General Practitioners (Nederlands Huisartsen Genootschap [NHG]) guideline 'Deep-vein thrombosis and pulmonary embolus' includes recommendations for the treatment of patients with deep-vein thrombosis (DVT) and thrombophlebitis, and for the exclusion of pulmonary embolism (PE). The general practitioner (GP) can exclude the presence of DVT or PE in some patients by using a decision rule and a D-dimer test. When using D-dimer test as a point-of-care test, meticulous care is essential during the test procedure and storage of blood. Read More

    Diagnosis of Mondor's Disease in the Emergency Department with Bedside Ultrasound.
    Case Rep Emerg Med 2015 18;2015:817960. Epub 2015 Jan 18.
    Department of Emergency Medicine, Loma Linda University, 11234 Anderson Street, A-108, Loma Linda, CA 92354, USA ; Division of Critical Care, Department of Internal Medicine, Loma Linda University, 11234 Anderson Street, A-108, Loma Linda, CA 92354, USA.
    Mondor's disease is a rare condition characterized by a superficial thrombophlebitis that can occur in the thoracoabdominal and genital areas. Findings with ultrasound in penile Mondor's disease are readily measurable: a noncompressible penile vein without flow and absence of tears of the corpus cavernosum or tunica albuginea, hematoma, or evidence of fracture of the penis. We present a case of Mondor's disease, diagnosed with bedside ultrasound, in the emergency department. Read More

    [Axillary web syndrome following axillary lymph node dissection for melanoma: 5 cases].
    Ann Dermatol Venereol 2015 Feb 24;142(2):94-8. Epub 2015 Jan 24.
    Service de chirurgie plastique reconstructrice et esthétique, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France.
    Background: Axillary web syndrome is a rare disease similar to Mondor's disease and is usually seen after axillary surgery. Herein, we describe five new cases, all of which occurred in a setting of melanoma.

    Patients And Methods: Five patients presented axillary web syndrome following sentinel node surgery, adenectomy or axillary curettage in a setting of melanoma. Read More

    Behçet's disease complicated with thrombosis: a report of 93 Chinese cases.
    Medicine (Baltimore) 2014 Dec;93(28):e263
    From the Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, 100730, China (XW, LW, YZ, WZ); Department of Nephrology, Inner Mongolia Hospital of Traditional Chinese Medicine, Hohhot, 010020, China (GL); Department of Rheumatology and Hematology, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China, 530021 (XH); and MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, 100084, China (WL).
    To investigate the clinical features of Behçet's disease (BD) complicated with thrombosis. Medical records of patients with BD at Peking Union Medical College Hospital from 1993 to 2013 were reviewed to identify thrombosis. Of the 766 patients with BD, 93 patients (16 female and 77 male) developed thrombosis. Read More

    Ten-year experience of recombinant activated factor VII use in surgical patients with congenital haemophilia with inhibitors or acquired haemophilia in Japan.
    Haemophilia 2015 May 18;21(3):374-9. Epub 2014 Dec 18.
    Hospital of the Institute of Medical Science of the University of Tokyo (IMSUT), Tokyo, Japan.
    Patients with congenital haemophilia with inhibitors or acquired haemophilia are at risk of bleeding complications during surgery. In these patients, replacement therapy for the missing coagulation factor is ineffective, and a bypassing agent such as recombinant activated factor VII (rFVIIa) is required to manage bleeding. To evaluate the safety and haemostatic efficacy of rFVIIa treatment in Japanese patients with congenital haemophilia with inhibitors to FVIII/FIX or acquired haemophilia undergoing surgery. Read More

    Superficial vein thrombosis: a current approach to management.
    Br J Haematol 2015 Mar 17;168(5):639-45. Epub 2014 Dec 17.
    Haemophilia and Thrombosis Centre, University Hospital of Wales, Cardiff, UK.
    Superficial vein thrombosis (SVT) was considered to be a benign and self-limiting condition. However, it is now appreciated that a significant proportion of those presenting with SVT will have concomitant deep vein thrombosis or pulmonary embolism, or are at significant risk of developing deep venous thromboembolism. Potential therapeutic options include topical preparations, compression therapy (stockings, bandages), medication such as non-steroidal anti-inflammatory drugs (NSAIDs) or anticoagulants (therapeutic or prophylactic doses) and surgery, ligation or stripping, of superficial veins. Read More

    [Phlegmasia cerulea dolens].
    Ann Dermatol Venereol 2014 Nov 12;141(11):682-4. Epub 2014 Aug 12.
    Service de dermatologie et médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France. Electronic address:
    Background: Herein we report a case of phlegmasia cerulea dolens, a form of venous thrombosis complicated by arterial ischaemia.

    Patients And Methods: A 69-year-old man presented a bilateral trophic condition of the lower limbs that had appeared 3 weeks earlier. The patient had a history of metastatic urothelial bladder carcinoma and arteritis. Read More

    Approach to the new oral anticoagulants in family practice: part 2: addressing frequently asked questions.
    Can Fam Physician 2014 Nov;60(11):997-1001
    Research fellow in the Department of Medicine at McMaster University.
    Objective: To address common "what if" questions that arise relating to the long-term clinical follow-up and management of patients receiving the new oral anticoagulants (NOACs).

    Sources Of Information: For this narrative review, we searched the PubMed database for recent (January 2008 to week 32 of 2013) clinical studies relating to NOAC use for stroke prevention in atrial fibrillation and for the treatment of acute venous thromboembolism. We used this evidence base to address prespecified questions relating to NOAC use in primary care settings. Read More

    A common presentation to an uncommon disease. Penile Mondor's disease: a case report and literature review.
    Int Med Case Rep J 2014 31;7:155-7. Epub 2014 Oct 31.
    Naval Air Station Lemoore, Lemoore, CA, USA.
    Penile Mondor's disease, or superficial thrombophlebitis of the dorsal vein of the penis, is a relatively uncommon but potentially anxiety-inducing self-limiting condition that should be easily recognizable by any primary care practitioner. It typically presents with a cord-like mass and pain to the dorsal penis and has a myriad of causes, including trauma, excessive sexual activity, excessive exercise, or malignancy. Although Penile Mondor's disease is typically a clinical diagnosis, Doppler ultrasound is the initial imaging modality of choice if there is question or doubt about the diagnosis. Read More

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