864 results match your criteria Thrombophlebitis Septic


A Curious Case of MRSA Bacteremia and Septic Pulmonary Embolism Secondary to Peripheral Venous Catheter.

Case Rep Crit Care 2021 9;2021:5544505. Epub 2021 Apr 9.

Staten Island University Hospital, Staten Island, NY 10305, USA.

Background: Central venous catheters (CVCs) have been frequently associated with septic thrombophlebitis, bacteremia, and septic emboli. Right-sided infective endocarditis is seen concurrently in patients with septic pulmonary emboli. A case of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and septic pulmonary emboli secondary to infected peripheral venous catheter (PVC) is reported. Read More

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Ophthalmic complications of Lemierre syndrome.

Acta Ophthalmol 2021 Apr 8. Epub 2021 Apr 8.

Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland.

Purpose: Lemierre syndrome is a life-threatening condition characterized by head/neck bacterial infection, local suppurative thrombophlebitis and septic embolic complications in a range of sites of distant organs. No prior study focused on the course and characteristics of ophthalmic complications of Lemierre syndrome.

Methods: We analysed data of 27 patients with ophthalmic complications from a large cohort of 712 cases with Lemierre syndrome reported globally between 2000 and 2017. Read More

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Forget-me-not: Lemierre's syndrome, a case report.

J Am Coll Health 2021 Mar 24:1-5. Epub 2021 Mar 24.

Division of Ambulatory Care, Department of Emergency Medicine, West Virginia University, Morgantown, West Virginia, USA.

Familiarity breeds complacency. One case of sore throat can start to sound like another. However, even common viral and bacterial infections can lead to serious sequelae. Read More

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A rare, but life-threatening sore throat: A case of Lemierre's syndrome.

Acute Med 2021 ;20(1):78-82

MB, BCh, BAO, FRCP, PhD, Acute Medicine Unit, Wards 7B and 7C, Royal Victoria Hospital, Belfast.

We present the case of a previously healthy, immunocompetent male with Lemierre's Syndrome. He presented with headache, sore throat and pyrexia. Initial blood tests revealed raised inflammatory markers and electrolyte abnormalities. Read More

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Care cascade for patients with opioid use disorder and serious injection related infections.

Toxicol Commun 2021 10;5(1):6-10. Epub 2021 Feb 10.

Department of Emergency Medicine, Washington University in St. Louis School of Medicine.

Objectives: To define the care cascade for patients with serious injection drug use related infections (SIRI) in a tertiary hospital system and compare outcomes of those who did and did not participate in an opioid use disorder (OUD) treatment referral program.

Methods: The medical records of patients admitted with both OUD and SIRI including endocarditis, osteomyelitis, septic arthritis, epidural abscess, thrombophlebitis, myositis, bacteremia, and fungemia from 2016-2019 were retrospectively reviewed. Patient demographics, clinical covariates, 90-day readmission rates, and outcomes data were collected. Read More

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February 2021

Sex differences in Lemierre syndrome: Individual patient-level analysis.

Thromb Res 2021 Mar 6;202:36-39. Epub 2021 Mar 6.

Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany; Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland. Electronic address:

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Lemierre's Syndrome with Severe Thrombocytopenia without Disseminated Intravascular Coagulation: A Case Report and Literature Review.

Am J Med Case Rep 2021 13;9(3):158-162. Epub 2021 Jan 13.

Department of Medicine, SUNY-Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, New York 11203, USA.

Lemierre's syndrome (LS) is an uncommon clinical entity characterized by a primary oropharyngeal infection with subsequent septic thrombophlebitis. Diagnosis is made with clinical or radiographic evidence of internal jugular vein (IJV) thrombosis, along with metastatic focus such as lungs or joints. Life threatening thrombocytopenia in Lemierre's syndrome in the absence of disseminated intravascular coagulation (DIC) is rarely reported. Read More

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January 2021

An Atypical Presentation of Lemierre's Syndrome: Complicated by Thrombotic Thrombocytopenic Purpura.

Cureus 2021 Jan 15;13(1):e12728. Epub 2021 Jan 15.

Infectious Disease, Aventura Hospital and Medical Center, Miami, USA.

Lemierre's syndrome is an oropharyngeal infection complicated by septic thrombophlebitis of the internal jugular vein, bacteremia, and septic emboli. It mainly occurs in immunocompetent individuals and was first reported in the early 1900s by physician Andre Lemierre. A 23-year-old male presented to our institution with sore throat, difficulty swallowing, left-sided ear pain, nausea, vomiting, subjective fevers, general malaise, right-sided rib pain, and anorexia. Read More

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January 2021

Rickets and gross motor delay in a child with atopic dermatitis.

Oxf Med Case Reports 2021 Feb 15;2021(2):omaa143. Epub 2021 Feb 15.

PGY-3, Dayton Children's Hospital, Dayton, OH, USA.

We report a case of a 14-month-old boy with atopic dermatitis (AD) who presented to our hospital with hypocalcemic tetany and gross motor delay. Further laboratory and imaging confirmed the diagnosis of vitamin D deficiency and rickets. He was breastfeeding and on a restricted diet due to presumed multiple food allergies. Read More

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February 2021

Rare Complications of Acute Appendicitis: A Case Report.

Clin Pract Cases Emerg Med 2021 Feb;5(1):66-69

Beth Israel Deaconess Medical Center, Department of Emergency Medicine, Boston, Massachusetts.

Introduction: Appendicitis is a common disease, and as we have improved in early diagnosis and management of this disease process, late stage complications have become extremely rare, but can have indolent presentations.

Case Report: A 37-year-old male with no past medical history presented to the emergency department (ED) with vague abdominal pain as well as 12 days of cyclical fever. He had no significant findings on laboratory workup with the exception of a mild aspartate transaminase and alanine transaminase and relative neutrophilia between outpatient, urgent care, and ultimate ED visit. Read More

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February 2021

Internal jugular vein thrombosis associated with .

BMJ Case Rep 2021 Jan 20;14(1). Epub 2021 Jan 20.

Department of General Internal Medicine, Kokuho Asahi Chuo Hospital, Asahi, Chiba, Japan.

, which occurs as part of the oral microflora, is an uncommon cause of infection. However, it can cause serious bloodstream infections including infective endocarditis. Although oral bacteria, most commonly the spp, can cause internal jugular vein (IJV) thrombophlebitis, there are no reported cases of IJV thrombosis caused Here we report a patient with septic IJV thrombosis with bacteraemia. Read More

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January 2021

Effect of the vancomycin minimum inhibitory concentration on clinical outcomes in patients with methicillin-susceptible bacteraemia: a systematic review and meta-analysis.

BMJ Open 2021 01 15;11(1):e040675. Epub 2021 Jan 15.

Department of Clinical Pharmacology, Translational Medicine Research Center, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

Objective: The use of the vancomycin minimum inhibitory concentration (MIC) as a prognostic predictor in patients with methicillin-susceptible (MSSA) has been debated in the last decade. We performed a systematic review and meta-analysis to investigate whether an elevated vancomycin MIC is associated with a worse prognosis for patients with MSSA bacteraemia.

Design: Systematic review and meta-analysis. Read More

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January 2021

Jugular Vein Thrombosis and Anticoagulation Therapy in Lemierre's SyndromeA Post Hoc Observational and Population-Based Study of 82 Patients.

Open Forum Infect Dis 2021 Jan 29;8(1):ofaa585. Epub 2020 Nov 29.

Division of Infection Medicine, Department for Clinical Sciences Lund, Lund University, Lund, Sweden.

Background: Lemierre's syndrome is typically caused by where an oropharyngeal infection is followed by septic internal jugular vein thrombophlebitis with subsequent septic embolization. Yet, the pathogenesis of septic thrombophlebitis, differences dependent on the presence of jugular vein thrombosis, and the role of anticoagulant therapy are insufficiently understood.

Methods: Patients with invasive infection with and Lemierre's syndrome who had been investigated for jugular vein thrombosis were included from a previous population-based observational study in Sweden. Read More

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January 2021

Lemierre's syndrome or re-emerging disease: Case report and literature review.

Int J Surg Case Rep 2021 Jan 9;78:151-154. Epub 2020 Dec 9.

ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Casablanca, Morocco. Electronic address:

Introduction: Lemierre's syndrome is a rare and potentially fatal entity characterized by the spread of an oropharyngeal infection, with secondary suppurative thrombophlebitis of the internal jugular vein and septic emboli.

Presentation Of Case: We discuss the case of a 52-year-old male who developed Lemierre's syndrome following peritonsillar abscess. He presented with submandibular and submental swelling extending into the neck. Read More

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January 2021

[A 'Trivial' Angina with Serious Consequences].

Praxis (Bern 1994) 2020 ;109(16):1271-1275

Medizinische Klinik Ospidal, Gesundheitszentrum Scuol.

A 'Trivial' Angina with Serious Consequences A 21-year old man presented with a septic shock two weeks after a pharyngitis. A thrombosis oft the internal jugular vein, septic systemic metastatic lesions and bacteriamia with Fusobacterium necrophorum led to the diagnosis of a Lemierre's syndrome - a rare complication of a pharyngitis with high morbidity and mortality, defined by a septic thrombophlebitis of the internal jugular vein with high risk of embolisation. A streptococcal-negative pharyngitis with red flags should therefore also be treated with antibiotics. Read More

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December 2020

Influence of the minimum inhibitory concentration of daptomycin on the outcomes of Staphylococcus aureus bacteraemia.

J Glob Antimicrob Resist 2021 Mar 3;24:23-26. Epub 2020 Dec 3.

Department of Infectious Diseases, Piedmont Columbus Regional Healthcare System, Columbus, GA, USA.

Objectives: Recent studies have shown that methicillin-resistantStaphylococcus aureus (MRSA) bacteraemia with vancomycin minimum inhibitory concentration (MIC) >1 μg/mL is associated with a higher rate of treatment failure and a higher mortality rate. Daptomycin is an alternative to vancomycin but has not been as well studied. The aim of this literature review was to evaluate the effect of daptomycin MIC on the outcomes of S. Read More

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The Use of Real-Time 3D Intraoperative Ultrasound "Angiography" in Localization and Occlusion Control of a Ruptured Mycotic Aneurysm: A Case Report.

J Neurol Surg A Cent Eur Neurosurg 2020 Dec 5. Epub 2020 Dec 5.

Department of Neurosurgery, School of Health Sciences, Democritus University of Thrace, Alexandroupolis, Greece.

Background:  Infectious (mycotic) aneurysms are rare with high mortality and are most commonly found at the distal branches of the middle cerebral artery (MCA). Because aneurysms of the distal MCA are located deep in the Sylvian fissure and are small in size, intraoperative identification and safe clip occlusion of these aneurysms are challenging. Thus, the use of intraoperative imaging and navigation can be beneficial. Read More

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December 2020

Lemierre's Syndrome Following Extraction of Wisdom Teeth.

Cureus 2020 Oct 20;12(10):e11061. Epub 2020 Oct 20.

Infectious Disease, University of Kansas School of Medicine, Wichita, USA.

Lemierre's syndrome is a rare but potentially fatal disease caused by oropharyngeal infections. It is characterized by thrombosis of the internal jugular vein leading to the systemic circulation of septic emboli. The common pathogen identified is Fusobacterium necrophorum. Read More

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October 2020

Lemierre's syndrome: a forgotten life-threatening entity.

BMJ Case Rep 2020 Oct 30;13(10). Epub 2020 Oct 30.

Otorhinolaryngology and Head and Neck Surgery Department, Centro Hospitalar de Vila Nova de Gaia, Porto, Porto, Portugal.

Lemierre's syndrome is a very rare but potentially fatal condition. It mainly affects adolescents and young adult males, and usually arises as a serious complication of pharyngitis or peritonsillar abscess. It is characterised by the triad of internal jugular vein septic thrombophlebitis, septic emboli (mostly pulmonary) and the isolation of the agent ' in sterile fluids. Read More

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October 2020

Streptococcal toxic shock syndrome revealed phlegmasia cerulea dolens of the arm.

Lancet Infect Dis 2020 11;20(11):1348

Service de chirurgie vasculaire, Centre Hospitalier Universitaire de Dijon, Dijon, France.

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November 2020

Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry.

Thromb Res 2020 12 8;196:494-499. Epub 2020 Oct 8.

Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany; Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland.

Lemierre syndrome is a rare but potentially fatal condition characterized by septic thrombophlebitis of the head and neck district, preferentially affecting adolescents and young adults and manifesting as a complication of a local bacterial infection - typically, a pharyngotonsillitis or an abscess. It is historically associated with the Gram-negative anaerobic rod Fusobacterium necrophorum and with thrombophlebitis of the internal jugular vein. However, its definition has never been firmly established, and its spectrum within the continuum of bacteria-associated thrombophlebitis may be larger than what presumed so far. Read More

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December 2020

Late presentation of 'Lemierre's syndrome': how a delay in seeking healthcare and reduced access to routine services resulted in widely disseminated infection during the global COVID-19 pandemic.

BMJ Case Rep 2020 Oct 10;13(10). Epub 2020 Oct 10.

Department of General Internal Medicine, St James's Hospital, Dublin, Ireland.

The SARS-CoV-2 outbreak has disrupted the delivery of routine healthcare services on a global scale. With many regions suspending the provision of non-essential healthcare services, there is a risk that patients with common treatable illnesses do not receive prompt treatment, leading to more serious and complex presentations at a later date. Lemierre's syndrome is a potentially life-threatening and under-recognised sequela of an oropharyngeal or dental infection. Read More

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October 2020

Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein.

Case Rep Surg 2020 16;2020:2343218. Epub 2020 Sep 16.

Department of General Surgery, Cantonal Hospital of Lucerne, Spitalstrasse, 6000 Lucerne 16, Switzerland.

Thrombophlebitis of the portal vein (pylephlebitis) is a rare but serious condition with a high mortality rate of 11-50%. A 56-year-old male patient presented with a two-day history of postprandial, colic-like epigastric pain, nausea, fever, chills, and diarrhea. Clinical workup showed peritonism, leukocytosis, and elevated C-reactive protein (CRP). Read More

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September 2020

A Rare Case Report of Lemierre Syndrome from the Anterior Jugular Vein.

Clin Pract Cases Emerg Med 2020 Aug;4(3):454-457

Hackensack University Medical Center, Department of Emergency Medicine, Hackensack, New Jersey.

Introduction: Lemierre syndrome is a rare, potentially fatal, septic thrombophlebitis of the internal jugular vein. Treatment includes intravenous antibiotics for Fusobacterium necrophorum, the most common pathogen, as well as consideration for anticoagulation therapy.

Case Report: A 27-year-old female presented with left-sided neck swelling and erythema. Read More

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Profile and correlates of injecting-related injuries and diseases among people who inject drugs in Australia.

Drug Alcohol Depend 2020 11 29;216:108267. Epub 2020 Aug 29.

National Drug and Alcohol Research Centre, 22-32 King st. Randwick, University of New South Wales Sydney, Sydney, Australia.

Introduction: People who inject drugs (PWID) commonly experience harms related to their injecting, many of which are consequences of modifiable drug use practices. There is currently a gap in our understanding of how certain injecting-related injuries and diseases (IRID) cluster together, and socio-demographic and drug use characteristics associated with more complex clinical profiles.

Method: Surveys were conducted with 902 Australian PWID in 2019. Read More

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November 2020

A Challenging Case of Lemierre's Syndrome With Central Nervous System Involvement and a Comprehensive Review.

Cureus 2020 Aug 30;12(8):e10131. Epub 2020 Aug 30.

Internal Medicine, Medical College of Wisconsin, Wauwatosa, USA.

Lemierre's syndrome (LS) is a complex medical condition that is characterized by an acute oropharyngeal infection leading to thrombophlebitis of the internal jugular vein and an eventual metastatic spread to distant vital organs. This metastatic spread is from septic emboli and is most frequently seen in the lungs, kidneys, and large joints. Central nervous system (CNS) involvement in LS is extremely rare, and only a few cases of CNS involvement have been reported in the literature. Read More

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Staphylococcus Aureus Panton-Valentine Leukocidin causing hip osteomyelitis, thrombophlebitis and necrotizing pneumonia in an immuocompetent child.

J Biol Regul Homeost Agents 2020 May-Jun;34(3 Suppl. 2):53-56

UO Degenza e Servizi di Riabilitazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome Italy.

Panton-Valentine leukocidin (PVL) represents an important virulence factor for many strains of . PVL is an esotoxin causing leucocyte destruction and tissue necrosis. We report on a case of osteomyelitis involving the hip joint with thromblophlebitis complicated by necrotizing pneumonia and life-threatening septic shock. Read More

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November 2020

Lemierre's syndrome in the pediatric population: Trends in disease presentation and management in literature.

Int J Pediatr Otorhinolaryngol 2020 Sep 23;136:110213. Epub 2020 Jun 23.

Boston Medical Center, Department of Otolaryngology - Head and Neck Surgery, Boston, USA. Electronic address:

Objective: This study aims to examine literature on Lemierre's Syndrome (LS) in the pediatric population over time in order to describe patterns in disease progression, management, and prognosis. In addition, this study assesses specific rate of literature output and the location of research over the past 10 years.

Methods: A literature review was conducted through two databases, PubMed. Read More

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September 2020

A Sporadic Case of Disseminated Fusobacterium Causing Pylephlebitis and Intracranial and Hepatic Abscesses in a Healthy Young Patient.

Cureus 2020 Jul 16;12(7):e9229. Epub 2020 Jul 16.

Neurology, Mount Sinai Hospital, New York, USA.

Fusobacterium species is known for being a causative agent for Lemierre's syndrome, which is characterized by thrombophlebitis of the jugular vein. However, Fusobacterium species causing Lemierre's variant gastrointestinal syndrome has only been reported in case reports. We present a case of Fusobacterium causing hepatic vein pylephlebitis, multiple brain abscesses, and hepatic abscess. Read More

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