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Ann Dermatol Venereol 2020 Jun 30. Epub 2020 Jun 30.

Dermatology department, Jean-Bernard hospital, Valenciennes, France.

Introduction: Ixekizumab is a recently developed biopharmaceutical used since 2016 in the US and Europe for the treatment of plaque psoriasis. Few adverse effects have been reported in the literature and ixekizumab is not known to increase the risk of viral reactivation. Herein we report the case of an immunocompetent female patient treated with ixekizumab who presented meningoradiculitis due to varicella zoster virus (VZV) reactivation. Read More

Arch Ital Urol Androl 2020 Jun 23;92(2). Epub 2020 Jun 23.

Department of Surgery, Unit of Urology, ATS Sardegna - ASSL Carbonia, Ospedale Sirai, Carbonia.

Mondor's disease is a rare superficial thrombophlebitis of subcutaneous vein and usually occurs in the anterior and lateral chest. Penile Mondor's disease is a rare condition characterized by superficial thrombophlebitis of the dorsal vein of the penis. We report a rare case of atypical penile Mondor's disease involved the right posterior scrotal vein, in a patient affected by essential thrombocythemia. Read More

Emerg Radiol 2020 Jun 24. Epub 2020 Jun 24.

Department of Radiology, Changi General Hospital, Singapore, Singapore.

The purpose of this pictorial essay is to review the imaging appearances of the spectrum of thrombophlebitis of abdominal veins on computed tomography (CT) scans. Thrombophlebitis of abdominal veins is rare but mimics other more common conditions presenting with acute abdomen. Due to non-specific presenting symptoms, signs and laboratory findings, diagnosis is largely reliant on imaging, particularly CT which is readily available in the emergency setting. Read More

Front Immunol 2020 2;11:993. Epub 2020 Jun 2.

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

To evaluate the short term safety and potential therapeutic effect of allogenic adipose tissue-derived stromal/stem cells (ASCs) + cholecalciferol in patients with recent-onset T1D. Prospective, phase II, open trial, pilot study in which patients with recent onset T1D received ASCs (1 × 10 cells/kg) and cholecalciferol 2000 UI/day for 3 months (group 1) and were compared to controls with standard insulin therapy (group 2). Adverse events, C-peptide (CP), insulin dose, HbA1c, time in range (TIR), glucose variability (continuous glucose monitoring) and frequency of CD4FoxP3+ T-cells (flow cytometry) were evaluated at baseline (T0) and after 3 months (T3). Read More

Phlebology 2020 Jun 24:268355520935744. Epub 2020 Jun 24.

Department of Vascular Surgery, St. Josef Hospital Bochum, Katholisches Klinikum Bochum, Ruhr University Bochum, Germany.

Objectives: Advanced phlegmasia cerulea dolens can be a hazardous complication of a deep vein thrombosis and rapid recanalization of the deep venous system is the most important factor.

Method: We describe the outcome of 17 patients with critical limb ischemia due to an advanced phlegmasia cerulea dolens. Venous thrombectomy was performed by a standardized operating procedure. Read More

J Ultrasound 2020 Jun 23. Epub 2020 Jun 23.

Radiodiagnostic and Radiotherapy Unit, Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", Via Santa Sofia 78, 95123, Catania, Italy.

May-Thurner syndrome (MTS) is a congenital vascular alteration that is part of a restricted category of very rare vascular syndromes that have in common the compression of an arterial or venous vessel. MTS, first described in 1957, is due to compression of the left common iliac vein against the lumbar spine by the adjacent common iliac artery. It can cause chronic thrombosis of the left lower limb and can give edema, pain, claudication, thrombophlebitis, and, in severe cases, pulmonary embolism. Read More

Neurohospitalist 2020 Jul 6;10(3):221-223. Epub 2019 Dec 6.

Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

We report a case of a 22-year-old male with a history of intravenous drug use presenting with cavernous sinus syndrome secondary to cavernous thrombophlebitis. The source of the thrombophlebitis was from a mycotic aneurysm in the setting of fungal endocarditis. With antifungal therapy and aortic valve replacement, the patient had full resolution of cranial nerve deficits. Read More

Cureus 2020 May 8;12(5):e8023. Epub 2020 May 8.

Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Klippel-Trenaunay Syndrome (KTS) is a rare and sporadic congenital disorder, characterized by the classical triad of port-wine stains, varicosities along with bone and soft tissue hypertrophy. Symptoms of Klippel-Trenaunay Syndrome include pain, swelling, lymphedema, bleeding, superficial thrombophlebitis, and deep vein thrombosis. The etiology remains indistinct and has been attributed to both genetic and environmental factors. Read More

J Infect Public Health 2020 Jun 2. Epub 2020 Jun 2.

Department of Pediatrics, King Abdullah Specialized Children's Hospital, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

A pre-school aged boy presented to the Pediatric Emergency Department with a high grade fever and neck pain and stiffness. Blood culture was positive for methicillin-sensitive Staphylococcus aureus (MSSA) and Doppler ultrasound of the neck revealed partial thrombosis of the left internal jugular vein. He was diagnosed with Lemierre's syndrome (LS) and treated with a prolonged course of antibiotics and anticoagulation. Read More

Dermatol Ther 2020 Jun 4:e13768. Epub 2020 Jun 4.

Department of Dermatology, Guglielmo Marconi University, Rome, Italy.

Medicine (Baltimore) 2020 May;99(22):e20332

Department of Plastic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

Background: There is a continued discussion on which is the best sclerosant to treat lower extremity varicose veins. Therefore, we did this meta-analysis to determine that foam sclerotherapy versus liquid sclerotherapy, which could perform better in the treatment of lower extremity varicose veins.

Materials And Methods: We independently searched 5 databases from inception to February 1, 2019, for randomized controlled trials and prospective controlled trials for comparing foam sclerotherapy and liquid sclerotherapy for the treatment of lower extremity varicose veins. Read More

J Artif Organs 2020 May 30. Epub 2020 May 30.

Hopital Universitaire Pitie Salpetriere, Paris, France.

Spinal cord infarction (SCI) is a rare disease among central nervous system vascular diseases. Only a little is known about venoarterial extracorporeal membrane oxygenation (VA-ECMO)-related SCI. Retrospective observational study conducted, from 2006 to 2019, in a tertiary referral center on patients who developed VA-ECMO-related neurovascular complications, focusing on SCI. Read More

Cureus 2020 Apr 22;12(4):e7787. Epub 2020 Apr 22.

Infectious Disease, State University of New York (SUNY) Upstate Medical University, Syracuse, USA.

Lemierre's syndrome is a rare but life-threatening condition characterized by an oropharyngeal infection typically secondary to Fusobacterium necrophorum resulting in septic thrombophlebitis of the internal jugular vein. Streptococcus intermedius is a particularly rare cause of Lemierre's syndrome with only a few cases reported in the literature. Here we describe a rare case of Lemierre's syndrome, caused by Streptococcus intermedius, likely secondary to an odontogenic infection, found to have a cervical epidural abscess with concomitant large retropharyngeal and prevertebral abscesses on presentation, in whom the clinical course was further complicated by an extensive cerebral venous sinus thrombosis. Read More

Int J Cardiol 2020 May 20. Epub 2020 May 20.

Department of Cardiology, Cardiology I, University Medical Center Mainz (Johannes Gutenberg-University Mainz), Mainz, Germany.

Background: Pulmonary embolism (PE) is a frequent cause of death and morbidity. A few studies suggest that clot burden in pulmonary artery bed is related to PE patients' survival, but the impact of concomitant deep venous thrombosis and/or thrombophlebitis (DVT) on short-term survival of PE patients remains unclear. Thus, we aimed to investigate the impact of DVT on adverse outcomes in PE patients. Read More

J Matern Fetal Neonatal Med 2020 May 22:1-8. Epub 2020 May 22.

Atlanta Perinatal Associates, Atlanta, GA, USA.

Complication rates associated with peripherally inserted central catheters (PICCs) in the general population are variable, and rates specific to pregnant women are unclear. We conducted a systematic review and meta-analysis to estimate the rate of PICC-associated complications in pregnant women. We searched published literature for records discussing PICC use in pregnant or postpartum women. Read More

Phlebology 2020 May 16:268355520925022. Epub 2020 May 16.

Hematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy.

Mondor's disease is a rare condition and usually treated with low-molecular weight heparin and non-steroidal anti-inflammatory drugs. Because of paucity of cases and for the usually spontaneous resolution, there is not a standard treatment strategy and the use of oral anticoagulation in controversial. We reported the efficacy of direct oral anticoagulants in the recurrent Mondor's disease refractory to standard therapy. Read More

J Med Vasc 2020 May 15;45(3):168-170. Epub 2020 Apr 15.

Department of Infectious Diseases, Farhat-Hached University hospital, 4000 Sousse, Tunisia; University of Sousse, Faculté de Médecine Ibn-Al-Jazzar, 4000 Sousse, Tunisia.

Rev Med Interne 2020 May 1. Epub 2020 May 1.

AP-HP, hôpital Louis-Mourier, service de réanimation médico-chirurgicale, 92700 Colombes, France; Centre hospitalier Sud Francilien, service de réanimation médico-chirurgicale, 91100 Corbeil-Essonnes, France.

Introduction: Lemierre's syndrome is defined as an oropharyngeal infection due to Fusobacterium necrophorum, associated with septic thrombophlebitis of the internal jugular vein. The uncommon pelvic variant of the syndrome is a rare condition, poorly described in literature.

Case Report: We report a case of gynecological Lemierre's syndrome in a 19-year-old woman after a first sexual intercourse, who presented acute respiratory failure, left internal iliac vein thrombosis with pulmonary embolism, in the setting of salpingitis and F. Read More

J Vasc Surg Venous Lymphat Disord 2020 Apr 27. Epub 2020 Apr 27.

Department of Surgery, Stony Brook Medicine, Stony Brook, NY. Electronic address:

Background: Initial phase III clinical studies with polidocanol endovenous microfoam (PEM) demonstrated its safety and efficacy in the treatment of superficial venous reflux. In those studies, the primary outcome requirement was to assess the improvement in symptoms related to superficial venous disease. The goal of the present study was to evaluate the efficacy of PEM technology in routine clinical practice-specifically, the closure rates after treatment. Read More

J Thromb Haemost 2020 Jun 28;18(6):1268-1270. Epub 2020 Apr 28.

Vascular Diseases Centre, University of Ferrara, Ferrara, Italy.

The model of Rembrandt's Bathsheba, a celebrated painting of the Louvre Museum in Paris, was his lover Hendrickje Stoffels. The picture has periodically caught the attention of the medical community because Hendrickje appears to have a condition affecting her left breast. Generally breast cancer has been proposed. Read More

Internist (Berl) 2020 Jun;61(6):617-620

Krankenhaus Bad Waldsee, Oberschwabenklinik gGmbH, Robert-Koch-Straße 38, 88339, Bad Waldsee, Deutschland.

The case of a 72-year-old female patient with exanthem and concomitant neuropathy of the instep of the foot and progressive ipsilateral lower leg pain is reported. Sonographically, a superficial vein thrombosis with extension into the deep venous system originating from the exanthem was observed. On the basis of the clinical picture as well as the serological and electrophysiological findings, a rare diagnosis of acrodermatitis chronica atrophicans with peripheral neuropathy was made, which could significantly promote the local development of venous thrombosis. Read More

Pan Afr Med J 2020 16;35:14. Epub 2020 Jan 16.

Service de Réanimation, CHU Mohamed VI, Faculté de Médecine et de Pharmacie d'Oujda, Université Mohammed 1 Oujda, Oujda, Maroc.

Cerebral thrombophlebitis is a rare but severe disease whose underestimated frequency is increasingly recognized among children and, unlike adults, management is controversial. We report the case of a 12-year old child bitten by a friend at the level of the scalp, in the frontotemporal region of the head. This bite evolved due to the occurrence of a swelling evoking a frontotemporoparietal cellulitis complicated by cerebral thrombophlebitis, diagnosed based on the clinical feature and imaging. Read More

Clin Ter 2020 May-Jun;171(3):e192-e196

Institute of Legal Medicine, University "Magna Graecia" of Catanzaro, Italy.

Septic pulmonary embolism (SPE) is an uncommon disease in which a microorganism- containing thrombus causes an inflammatory reaction and a mechanical obstruction in the vascular system of the lungs. Usually it is associated with tricuspid valve vegetation, septic thrombophlebitis or infected venous catheters. We present a rare and fatal case of massive septic pulmonary thromboembolism occurred in a diabetic woman, who complained in previous days dyspnoea, abdominal pain and nausea. Read More

J Arthroplasty 2020 Mar 21. Epub 2020 Mar 21.

Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.

Background: Nonagenarians and centenarians are among the fastest growing demographics in the United States. Although consequent demand for joint replacement is projected to rise precipitously, outcomes of total hip arthroplasty (THA) have seldom been studied in this population.

Methods: A retrospective cohort of patients undergoing primary THA was established using the 2008-2017 American College of Surgeons National Quality Improvement Program. Read More

J Microbiol Immunol Infect 2020 Apr 4. Epub 2020 Apr 4.

Departments of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

Lemierre's syndrome, also known as post-anginal septicemia or necrobacillosis, is characterized by bacteremia, internal jugular vein thrombophlebitis, and metastatic septic emboli secondary to acute pharyngeal infections. Modern physicians have "forgotten" this disease. The most common causative agent of Lemierre's syndrome is Fusobacterium necrophorum, followed by Fusobacterium nucleatum and anaerobic bacteria such as streptococci, staphylococci, and Klebsiella pneumoniae. Read More

Cureus 2020 Mar 28;12(3):e7443. Epub 2020 Mar 28.

Internal Medicine, Aventura Hospital and Medical Center, Aventura, USA.

Lemierre syndrome is a life-threatening condition associated with infection by obligate anaerobes residing in oropharyngeal mucosa. The most common organism responsible is Fusobacterium necrophorum. We report a case in a 69-year-old gentleman. Read More

Case Rep Infect Dis 2020 16;2020:4346937. Epub 2020 Mar 16.

Lewis-Gale Hospital Montgomery, 3700 South Main St., Blacksburg, VA 24060, USA.

Once coined the "Forgotten Disease," Lemierre's syndrome is a rare condition that results from oropharyngeal infection with the gram-negative, anaerobic . The typical progression of illness involves spread to adjacent structures such as the internal jugular vein with resulting thrombophlebitis. Septic emboli to distant sites are also a common sequela. Read More

Vascular 2020 Mar 30:1708538120913734. Epub 2020 Mar 30.

Department of Cardiovascular and Thoracic Surgery, Jacobi Medical Center, Bronx, NY, USA.

Background: Lemierre's syndrome is a rare but potentially fatal condition. The course is characterized by acute tonsillopharyngitis, bacteremia, internal jugular vein thrombosis, and septic embolization. There have been some cases secondary to penetrating trauma to the neck. Read More

IDCases 2020 6;19:e00664. Epub 2019 Nov 6.

Department of Infectology and Geographical Medicine, Faculty of Medicine, Comenius University in Bratislava, Limbova 5, 831 01, Slovak Republic.

is an extremely rare case of the Lemierre syndrome, which is characterized as septic thrombophlebitis of the jugular vein as a consequence of oropharyngeal infection. We present a unique case of Lemierre syndrome caused by complicated by epidural abscess. The patient presented with fever, severe nuchal pain and stiffness and mild sore throat and headache. Read More

J Vasc Surg Venous Lymphat Disord 2020 Mar 20. Epub 2020 Mar 20.

Department of Statistics, Purdue University, West Lafayette, Ind.

Background: Insurance approval for saphenous vein ablation is generally limited to junctional reflux involving the great saphenous vein (GSV) or small saphenous vein. This study was designed to investigate prevalence and disease severity of anterior accessory GSV (AAGSV) compared with GSV disease in patients presenting to dedicated outpatient vein centers.

Methods: Deidentified data were pulled from the American Vein & Lymphatic Society PRO Venous Registry for first and second patient encounters. Read More

J Vasc Surg Venous Lymphat Disord 2020 Mar 18. Epub 2020 Mar 18.

Department of Radiology and Policlinic of Radiology, University Hospital Halle (Saale), Halle (Saale), Germany.

Objective: The aim of this study was to evaluate the safety and clinical outcomes of percutaneous sclerotherapy of venous disorders of the labia majora in patients with vascular malformations of the lower limbs.

Methods: Thirty percutaneous sclerotherapy treatments were performed over a 6-year period among 17 female patients with symptomatic venous malformation (VM) or secondary varicosis of the labia majora. Four patients were treated with sclerotherapy alone, 13 patients had additional procedures to control the VM before sclerotherapy. Read More

Cureus 2020 Feb 7;12(2):e6917. Epub 2020 Feb 7.

Emergency Medicine, St. Mary Mercy Hospital, Livonia, USA.

Thrombophlebitis of a subcutaneous vein, known as Mondor's disease, is a rare cause of chest pain and can mimic several more life-threatening diseases. Mondor's disease can be caused by trauma, or hypercoagulable states; however, in many cases the etiology is unknown. Mondor's disease is usually self-limited and can be managed conservatively. Read More

Dtsch Arztebl Int 2020 02;116(8):125

Int J Surg Case Rep 2020 19;68:170-173. Epub 2020 Feb 19.

Department of Pathology, Pt. B D Sharma PGIMS, Rohtak, India. Electronic address:

Introduction: Respiratory distress is an uncommon clinical event after caesarean section and occurs due to pulmonary thromboembolism. Various causes of pulmonary thromboembolism are thrombophlebitis, ovarian venous thrombosis and mesenteric vein thrombosis.

Presentation Of Case: We report a case of 30 year old female who presented with respiratory distress after eight days of uneventful caesarian section. Read More

Cardiovasc Res 2020 Mar 6. Epub 2020 Mar 6.

Population Health Research Institute, Hamilton, Ontario, Canada.

Aim: To examine the rates of VTE in high-income, upper middle-income and lower middle/low-income countries (World Bank Classification).

Methods And Results: We examined the rates of VTE in high-income, upper middle-income and lower middle/low-income countries (World Bank Classification) in a cohort derived from four prospective international studies (PURE, HOPE-3, ORIGIN, COMPASS). The primary outcome was a composite of pulmonary embolism, deep vein thrombosis and thrombophlebitis. Read More

Georgian Med News 2020 Jan(298):13-16

Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.

Acute thrombophlebitis of the superficial veins is an urgent problem as it can spread to the deep veins with the subsequent development of pulmonary embolism. The social implications of varicotrombophlebitis are the long-term disability of most patients up to complete disability, so finding the least invasive methods of correction of the discussed disease is a pressing issue of modern phlebology. The research objective is to carry out a comparative analysis of the quality of life of patients with acute ascending thrombophlebitis of the great sapheneous vein after treatment with high-frequency endovenous welding and standard phlebectomy. Read More

Eur Rev Med Pharmacol Sci 2020 Feb;24(4):2020-2027

Department of Cardiology, Xuanwu Hospital of Capital Medical University, Beijing, China.

Objective: To explore the effect of the micro ribonucleic acid (miR)-223 on the thrombophlebitis rats by regulating the Toll-like receptor (TLR) signaling pathway.

Materials And Methods: The rat model of thrombophlebitis was established, and miR-223 was silenced or overexpressed through lentiviral transfection. The rats were divided into miR-223 inhibitors group (Inhibitors group), miR-223 mimics group (Mimics group), and normal group (Control group). Read More

Pediatr Hematol Oncol 2020 May 6;37(4):344-352. Epub 2020 Mar 6.

Department of Pediatrics, UC San Diego, La Jolla, California, USA.

Septic thrombophlebitis is a potentially life-threatening condition. Pediatric hematologists are often consulted to provide recommendations regarding anticoagulation management. We conducted a ten-year retrospective, single-center study of hospitalized pediatric patients who were treated for septic thrombophlebitis. Read More

Pediatrics 2020 04 4;145(4). Epub 2020 Mar 4.

Department of Pediatrics, Upstate Medical University, State University of New York, Syracuse, New York

An adolescent girl with a history of frequent electronic cigarette use of nicotine was hospitalized with severe necrotizing pneumonia. Blood cultures obtained before the administration of empirical broad-spectrum intravenous antibiotics had positive results for the growth of The pathogen is an uncommon but well-known cause of anaerobic pneumonia with unique features that are collectively referred to as Lemierre syndrome or postanginal sepsis. The syndrome begins as a pharyngeal infection. Read More

Natl Med J India 2019 May-Jun;32(3):134-136

Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.

Background: Thromboangiitis obliterans (TAO) or Buerger disease is a recurring progressive segmental vasculopathy that presents with inflammation and thrombosis of small and medium arteries and veins of the hands and feet. The exact cause remains unknown, with tobacco use (primarily smoking but also smokeless tobacco) being highly associated with the disease. The diagnosis is clinical and the lack of a diagnostic gold standard is a deterrent to diagnosing it in patients with atypical presentations. Read More

Int J Infect Dis 2020 May 29;94:110-115. Epub 2020 Feb 29.

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, Rome, Italy. Electronic address:

Background: Data on septic thrombosis caused by Gram-negative bacilli (GN-ST) in intensive care unit (ICU) patients are currently limited.

Methods: The aim of this retrospective case-control study (matched 1:3) performed over a 15-month period on ICU patients with bacteraemia, associated (cases) or not (controls) with GN-ST, was to assess 30-day mortality and clinical/microbiological features of GN-ST.

Results: During the study period, 16 patients with GN-ST and 48 controls were analyzed. Read More

Ci Ji Yi Xue Za Zhi 2020 Jan-Mar;32(1):91-95. Epub 2019 Jun 6.

Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.

Internal jugular vein thrombosis is a rare critical cardiovascular emergency, which has potential catastrophic clinical outcomes by resulting in stroke and pulmonary embolism. Several etiologies have been reported; however, there are limited data on Lemierre's and Trousseau's syndromes, which are both rare conditions with advanced disease progression and poor clinical outcomes. Lemierre's syndrome may present with typical progressively infectious symptoms and signs, including sore throat, neck mass, and fever, whereas Trousseau's syndrome may present with thrombophlebitis and painful edema. Read More

Case Rep Gastrointest Med 2020 13;2020:3918080. Epub 2020 Feb 13.

Internal Medicine, University of South Dakota Sanford School of Medicine, Vermillion, SD 57069, USA.

Pylephlebitis is a condition in which there is septic thrombophlebitis of the portal-mesenteric venous system. It is a rare condition that usually arises as a complication of an intra-abdominal infection or inflammation. Being rare, it may be overlooked as a differential in cases of abdominal pain when the more common causes have been excluded. Read More

Cureus 2020 Jan 15;12(1):e6665. Epub 2020 Jan 15.

Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Protein C (PC) and protein S (PS) are natural anticoagulants that protect the body against thrombosis, and their deficiency, either inherited or acquired, renders the body to a hypercoagulable state. This leads to venous thromboembolism manifesting as thrombosis, pulmonary embolism and superficial thrombophlebitis among other causes. The involvement of arteries is rare and has been explained by only a few studies. Read More

Eur J Clin Microbiol Infect Dis 2020 Jul 15;39(7):1315-1320. Epub 2020 Feb 15.

Department of Radiology, Shengjing Hospital of China Medical University, NO. 36, Sanhao Street, Heping District, Shenyang, 110004, China.

The pathogenic bacterium Klebsiella pneumoniae (KP) is the major causative agent of pyogenic liver abscess (PLA). But reports about the prognosis of KP-caused PLA (KPLA) are rare. This study aimed to ascertain the recurrence rate of KPLA after initial treatment and its contributing factors. Read More

Enferm Infecc Microbiol Clin 2020 Feb 11. Epub 2020 Feb 11.

Unit of Infectious Diseases, Hospital Universitario "12 de Octubre", Instituto de Investigación Hospital "12 de Octubre" (imas12), School of Medicine, Universidad Complutense, Madrid, Spain. Electronic address:

Introduction: Data concerning the use of peripherally inserted central catheters (PICC) for the administration of intravenous (IV) antimicrobials in the acute care setting is scarce.

Methods: We performed a single-center retrospective case-control study (1:1). Case subjects were defined as patients who received IV antimicrobial treatment through a PICC line placed and maintained by specifically trained nurses (PICC group). Read More