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    1 OF 476

    Lesson of the month 1: Lemierre's syndrome: a reminder of the 'forgotten disease'.
    Clin Med (Lond) 2018 Feb;18(1):100-102
    Barts Health NHS Trust, London, UK.
    Lemierre's syndrome is a condition characterised by suppurative thrombophlebitis of the internal jugular (IJ) vein following a recent oropharyngeal infection, with resulting septicaemia and metastatic lesions. It is strongly associated with Fusobacterium necrophorum, a Gram-negative bacilli. Key to early diagnosis is awareness of the classical history and course of this illness, and therefore to ask about a history of recent oropharyngeal infections when a young patient presents with fever and rigors. Read More

    Hughes-Stovin Syndrome as an Outcome of Behçet Disease or as a Different Entity.
    Korean J Thorac Cardiovasc Surg 2018 Feb 5;51(1):64-68. Epub 2018 Feb 5.
    Department of Cardiovascular Surgery, Kirikkale University Faculty of Medicine.
    Hughes-Stovin syndrome is a rare disorder of unknown etiology. Although the association between multiple pulmonary artery aneurysms and venous thrombosis of the lower limbs was reported by Beattie and Hall in 1911, it was not until 1962 that the eponym "Hughes-Stovin syndrome" was formally introduced in the medical literature. We describe 2 patients with Hughes-Stovin syndrome who presented with pulmonary artery aneurysm, thrombophlebitis, hemoptysis, and oral ulcers, review the manifestations of the disease, and compare its similarities with and differences from Behçet disease. Read More

    Pubic and inguinal venous collaterals mimic inguinal hernia.
    J Surg Case Rep 2017 Aug 22;2017(8):rjx113. Epub 2017 Aug 22.
    Department of General, Visceral and Transplant Surgery, Hannover Medical School, Hannover, Germany.
    Herein we report a case of a 38-year-old men who presented with acute suprapubic pain caused by a tubular, hypoechoic, non-compressible, inguinal mass with no flow evident on color Doppler sonography. The history of the patient, the clinical signs of local inflammation and tenderness on palpation as well as the results of the Doppler ultrasound examination led to the diagnose of an inguinal hernia with bowl incarceration. However, due to a remaining uncertainty whether a bilateral or unilateral hernia was immanent and whether the bowl incarceration was caused by a right or left sided hernia the on-call surgeon initiated a computed tomography (CT) scan. Read More

    Executive summary: Diagnosis and Treatment of Catheter-Related Bloodstream Infection: Clinical Guidelines of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC) and the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC).
    Enferm Infecc Microbiol Clin 2018 Feb;36(2):112-119
    Unidad de Cuidados Intensivos, Hospital Universitari Parc Taulí, Sabadell, Barcelona; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, España.
    Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Read More

    Diagnosis and treatment of catheter-related bloodstream infection: Clinical guidelines of the Spanish Society of Infectious Diseases and Clinical Microbiology and (SEIMC) and the Spanish Society of Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC).
    Med Intensiva 2018 Jan - Feb;42(1):5-36
    Unidad de Cuidados Intensivos, Hospital Universitari Parc Taulí, Sabadell, Barcelona; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
    Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Read More

    A Rare Finding of Falciform Ligament Thrombosis as a Sequel of Acute Pancreatitis.
    Case Rep Radiol 2017 18;2017:2879568. Epub 2017 Dec 18.
    Hairmyres Hospital, Glasgow G75 8RG, UK.
    Falciform ligament (remnant of umbilical vein) is an anatomical structure that connects the liver to the anterior abdominal wall. This case reports a rare clinical presentation of falciform ligament thrombosis as a consequence of acute gallstone pancreatitis, in a patient with noncirrhotic liver. A 55-year-old female with a history of cholelithiasis was admitted with abdominal pain. Read More

    Absent Inferior Vena Cava Leading to Recurrent Lower Extremity Deep Vein Thrombosis in a United States Marine.
    Mil Med 2018 Jan;183(1-2):e172-e174
    U.S. Navy Aviation Medicine, Marine Aircraft Group 14, PO Box 8051, Cherry Point, NC 28533.
    Introduction: Anomalies of the inferior vena cava (AIVC) are rare but well-recognized anatomic abnormalities that can lead to clinically significant deep vein thrombosis (DVT) in a subset of otherwise healthy patients. This report illustrates an uncommon congenital anomaly that military clinicians should consider when evaluating unprovoked DVT in young patients.

    Materials And Methods: Single case report and literature review. Read More

    Pseudocellulitis Need Not be Benign: Three Cases of Superficial Migratory Thrombophlebitis with "Negative" Venous Duplex Ultrasonography.
    J Clin Aesthet Dermatol 2017 Dec 1;10(12):49-51. Epub 2017 Dec 1.
    Dr. Tian is with Ohio State University College of Medicine in Columbus, Ohio.
    Trousseau syndrome is a rare phenomenon in cancer patients characterized by superficial migratory thrombophlebitis. In this brief report, the authors describe three recent case presentations of patients without a prior history of cancer who were treated for cellulitis prior to be admitted to the hospital. All three patients were found to have "negative" testing on venous duplex scanning. Read More

    Penile Mondor's disease in a patient treated with radical chemoradiation for anal cancer.
    Oxf Med Case Reports 2017 Aug 2;2017(8):omx036. Epub 2017 Aug 2.
    Department of Radiation Oncology, Bank of Cyprus Oncology Center 2006, Strovolos 2012, Nicosia, Cyprus.
    Penile Mondor's disease is a rare condition characterized by sclerosing thrombophlebitis of the superficial dorsal penile vein. Usually its causes are benign, but it is also evident in cancer patients. We report the case of a 62-year-old man with a cT4 anal cancer (infiltration of corpora spongiosa and penile bulb), associated with extensive loco-regional lymphadenopathy, who developed painful lumps in the midline of the anterior penile surface while receiving radical chemoradiotherapy. Read More

    Pythium Keratitis Leading to Fatal Cavernous Sinus Thrombophlebitis.
    Cornea 2018 Jan 9. Epub 2018 Jan 9.
    Department of Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of MAdical Sciences, New Delhi, India.
    Purpose: To report a case of Pythium insidiosum keratitis leading to fatal cavernous sinus thrombophlebitis.

    Methods: Case report.

    Results: A 70-year-old man presented with excruciating pain, redness, and diminution of vision in his left eye for 2 weeks after washing his hair with tap water. Read More

    Mondor's disease - a rare cause of chest pain: a case report.
    J Med Case Rep 2018 Jan 9;12(1). Epub 2018 Jan 9.
    Professorial Medical Unit, Teaching Hospital, Jaffna, Sri Lanka.
    Background: Chest pain is one of the common presenting symptoms encountered in an emergency department. Prompt history taking and careful clinical examination do help to differentiate cardiac chest pain from other causes. Mondor's disease is a rare cause of chest pain which is often underdiagnosed due to lack of awareness. Read More

    Behçet's disease in the United States: A single center descriptive and comparative study.
    Eur J Rheumatol 2017 Dec 3;4(4):239-244. Epub 2017 Nov 3.
    Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
    Objective: Behçet's disease is heterogeneous with clinical variability across ethnicities and geographic locations. The goal of this study was to analyze the clinical characteristics of our multi-ethnic Behçet's disease cohort at the University of Michigan.

    Material And Methods: A detailed patient characterization was performed. Read More

    septic thrombophlebitis following lower extremity amputation in an immunocompetent host.
    BMJ Case Rep 2018 Jan 6;2018. Epub 2018 Jan 6.
    Department of Infectious Diseases, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
    A 59-year-old man with a history of peripheral vascular disease status post femoral popliteal bypass presented with critical limb ischaemia of the left leg. An arterial Doppler ultrasound showed an occluded graft requiring an above knee amputation. Five days after surgery, the patient developed fever, leucocytosis, significant stump swelling and pain, and serosanguinous discharge from his wound. Read More

    Lemierre syndrome: a diagnostic dilemma in paediatric patients.
    J Surg Case Rep 2017 Dec 21;2017(12):rjx210. Epub 2017 Dec 21.
    Department of Imaging, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK.
    Lemierre's syndrome is a rare disease of the head and neck, characterized by an initial infection, usually within the oropharynx, which can develop into a septic thrombophlebitis. It can involve the jugular vein, facial veins and respiratory tract. A 7-year-old child attended our institution with a 1-week history of fever and cough. Read More

    Variant of Lemierre's syndrome with internal jugular vein aneurysm.
    BMJ Case Rep 2017 Dec 22;2017. Epub 2017 Dec 22.
    Department of Diagnostic Imaging, Hospital Tuanku Ja'afar, Seremban, Negeri Sembilan, Malaysia.
    Internal jugular vein (IJV) aneurysm is a rare entity, and a thrombosed aneurysm poses diagnostic and management challenges. We came across a 53-year-old woman who presented with fever, vomiting and right neck swelling for a week. Laboratory investigations showed neutrophilic leucocytosis, raised acute phase reactant and blood culture yieldedUltrasound and contrast-enhanced CT neck revealed a large fusiform aneurysm of the right IJV with filling defect extending from the aneurysm into the right transverse sinus. Read More

    Thromboembolism following cesarean section: a retrospective study.
    Hematology 2017 Dec 21:1-6. Epub 2017 Dec 21.
    h Departments of Medicine and Laboratory Medicine and Pathobiology , University of Toronto, Division of Hematology, Special Pregnancy Program, Mount Sinai Hospital , Toronto , Canada.
    Objectives: As thromboembolism (TE) continues to be one of the principal causes of death in obstetrical patients and as the postpartum period is associated with the highest risk for TE, we sought to determine the risk factors associated with TE following cesarean section (CS).

    Methods: A retrospective analysis of patients who had CS at a large tertiary referral center was conducted. Patients were identified through hospital medical records and were contacted approximately 1 year following their CS. Read More

    [Dysphagia and tonsillitis in a 25-year-old male patient : The nearly forgotten severe complication of a common ailment].
    Internist (Berl) 2017 Dec 18. Epub 2017 Dec 18.
    Klinik für Allgemeine Innere Medizin, Nephrologie und Dialyse, Hypertensiologie, Klinische Immunologie und Osteologie, St. Franziskus-Hospital GmbH, Hohenzollernring 72, 48145, Münster, Deutschland.
    We report the case of a patient with a severe dysphagia accompanying progressive tonsillitis. The clinical examination supported the possibility of a severe septic soft tissue infection. The blood cultures revealed a largely anaerobic sepsis with Fusobacterium necrophorum. Read More

    [Thromboangiitis obliterans: notions for practice].
    Rev Med Suisse 2017 Dec;13(586):2129-2133
    Service d'angiologie, Département cœur-vaisseaux, CHUV, 1011 Lausanne.
    Thromboangiitis obliterans is an occlusive vasculopathy affecting small- and medium-size arteries. It can result in severe ischemic status. Thrombophlebitis can be associated. Read More

    Human Infection withwithout Jugular Venous Thrombosis: A Varied Presentation of Lemierre's Syndrome.
    Case Rep Infect Dis 2017 24;2017:5358095. Epub 2017 Oct 24.
    Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
    Lemierre's syndrome is also known as postangina septicemia, which is commonly caused byalso known as Necrobacillus and also by other microorganisms like,,, and. Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. Read More

    Fusobacterium emphysematous pyomyositis with necrotizing fasciitis of the leg presenting as compartment syndrome: a case report.
    J Med Case Rep 2017 Nov 28;11(1):332. Epub 2017 Nov 28.
    Department of Surgery, University of Illinois at Chicago, Chicago, 60612, IL, USA.
    Background: Fusobacterium necrophorum is a common agent of disease in humans, but the occurrence of primary infections outside the head and neck area is extremely rare. While infection with Fusobacterium necrophorum has a rather benign course above the thorax, the organism is capable of producing very severe disease when located in unusual sites, including various forms of septic thrombophlebitis. No infections of the leg have been documented before; thus, antibiotic coverage for Fusobacterium is currently not recommended in this area. Read More

    [Maternal death by stroke. Results from the French enquiry into maternal deaths, 2010-2012].
    Gynecol Obstet Fertil Senol 2017 Dec 15;45(12S):S65-S70. Epub 2017 Nov 15.
    Département d'anesthésie-réanimation-SMUR, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address:
    Stroke is a rare event during pregnancy (10/100,000) and can be ischemic (24%), hemorrhagic (74%) or both (2%). Pregnancy probably increases the risk even if it is discussed for arteriovenous malformation (AVM), aneurismal subarachnoid hemorrhage (SAH) and cavernomas. Between 2010 and 2012, 31 maternal deaths were associated with stroke. Read More

    Vancomycin Infiltrate-Induced Dermatitis Mimicking Bullous Cellulitis.
    J Drugs Dermatol 2017 Nov;16(11):1160-1163

    Extravasation of medications can manifest as tenderness, pain, tissue necrosis, and thrombophlebitis and lead to infection and severe long-term complications. Risk factors for leakage of medications include mechanical and pharmacologic mechanisms such as cannulation technique, vasoconstriction, and cytotoxicity. Well-known vesicants like anthracyclines, vinca alkaloids, and vasopressors are usually administered with proper caution. Read More


    Lemierre's Syndrome - A rare cause of disseminated sepsis requiring multi-organ support.
    J Intensive Care Soc 2017 Nov 14;18(4):329-333. Epub 2017 Mar 14.
    Department of Anaesthesia, Ninewells Hospital, Dundee, UK.
    Lemierre's syndrome is a rare complication of acute pharyngitis characterised by septicaemia with infective thrombophlebitis of the internal jugular vein, most commonly due to. It characteristically affects healthy young adults causing persistent pyrexia and systemic sepsis presenting several days after an initial pharyngitis. Septic emboli seed via the bloodstream to distant sites including the lung, joints, skin, liver, spleen and brain. Read More

    Complications from Administration of Vasopressors Through Peripheral Venous Catheters: An Observational Study.
    J Emerg Med 2018 Jan 27;54(1):47-53. Epub 2017 Oct 27.
    Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
    Background: The placement of a central venous catheter for the administration of vasopressors is still recommended and required by many institutions because of concern about complications associated with peripheral administration of vasopressors.

    Objective: Our aim was to determine the incidence of complications from the administration of vasopressors through peripheral venous catheters (PVC) in patients with circulatory shock, and to identify the factors associated with these complications.

    Methods: This was a prospective, observational study conducted in the emergency department (ED) of a tertiary care medical center. Read More

    Ludwig's Angina.
    Cureus 2017 Aug 21;9(8):e1588. Epub 2017 Aug 21.
    Internal Medicine, Kettering Medical Center.
    Ludwig's angina is a diffuse cellulitis in the submandibular, sublingual, and submental spaces, characterized by its propensity to spread rapidly to the surrounding tissues. Early recognition and treatment for Ludwig's angina are of paramount importance due to the myriad of complications that can occur in association with Ludwig's angina. Known complications of Ludwig's angina include carotid arterial rupture or sheath abscess, thrombophlebitis of the internal jugular vein, mediastinitis, empyema, pericardial effusion, osteomyelitis of the mandible, subphrenic abscess, aspiration pneumonia, and pleural effusion. Read More

    Lemierre's syndrome variant of the gut.
    BMJ Case Rep 2017 Oct 20;2017. Epub 2017 Oct 20.
    Department of Internal Medicine, Washington DC VA Medical Center, Washington, D.C., USA.
    Infectious suppurative thrombophlebitis of the portal venous system, referred to as pylephlebitis, is a rare complication of intra-abdominal inflammatory processes. Advances in diagnostics and antibiotics have improved survival, but mortality remains remarkably high even in the most recent literature. The majority of patients have concomitant bacteraemia on presentation most commonly with typical gastrointestinal (GI) organisms. Read More

    Some neck swellings are serious; a case of Lemierre's Syndrome.
    J Community Hosp Intern Med Perspect 2017 Oct 19;7(4):251-254. Epub 2017 Sep 19.
    Department of Pulmonary and Critical Care, Abington Jefferson Health, Abington, PA, USA.
    Lemierre's syndrome also termed post-anginal septicemia, is a disease characterized by internal jugular septic thrombophlebitis leading to Fusobacterium septicemia with multiple metastatic foci following an oropharyngeal infection. Diagnosis and management is challenging and can result in fatal consequences due to potential multisystem involvement and multiple complications. We describe here a case of Lemierre's syndrome with multifocal pneumonia, acute renal failure and protracted course of illness over forty days with successful recovery. Read More

    Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency.
    Intern Med 2018 Jan 16;57(2):209-212. Epub 2017 Oct 16.
    Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan.
    A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed severe rectal wall thickening with partial defect of enhancement. Read More

    Potential application of immobilized streptokinase extracted from Streptococcus equinus VIT_VB2.
    Prep Biochem Biotechnol 2017 Nov 20;47(10):1032-1036. Epub 2017 Nov 20.
    a Department of Biotechnology, School of Biosciences and Technology , VIT University , Vellore , Tamil Nadu , India.
    Streptokinase purified from Streptococcus equinus VIT_VB2 isolated from bovine milk sample was immobilized in various solid supports namely entrapment in agarose gel, calcium alginate beads and gelatin gel by cross-linking with formaldehyde. Immobilization of streptokinase in calcium alginate beads showed maximum efficiency (81.8 ± 1. Read More

    Is Infection an Independent Risk Factor for Venous Thromboembolism? A Population-Based, Case-Control Study.
    Am J Med 2017 Oct 4. Epub 2017 Oct 4.
    Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minn; Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minn.
    Background: The independent association of recent infection with venous thromboembolism is uncertain. The study aims were to test both overall infection (site unspecified) and specific infection sites as potential risk factors for deep vein thrombosis and pulmonary embolism adjusting for other known venous thromboembolism factors.

    Methods: By using Rochester Epidemiology Project resources, we identified all Olmsted County, Minnesota, residents with objectively diagnosed incident deep vein thrombosis or pulmonary embolism over the 13-year period 1988 to 2000 (cases; n = 1303) and 1 to 2 residents without venous thromboembolism matched to each case on age, sex, and incident venous thromboembolism date (controls; n = 1494). Read More

    Lesson of the month 1: Spontaneous septic thrombophlebitis presenting with bacteraemia diagnosed by PET-CT scan.
    Clin Med (Lond) 2017 Oct;17(5):471-472
    Southend University Hospital NHS Foundation Trust, Southend, UK.
    Spontaneous septic thrombophlebitis is a rare complication ofbacteraemia. Its true incidence is unknown as septic thrombus is not often considered as a source in the typical 'screen' of tests used to find the source of a bacteraemia.Positron emission tomography computerised tomography (PET-CT) is becoming increasingly available to physicians, is highly sensitive and yields specific anatomical information regarding abnormal metabolically active sites in infection, inflammation and neoplasia. Read More

    Treatment of incompetent perforators in recurrent venous insufficiency with adhesive embolization and sclerotherapy.
    Phlebology 2017 Jan 1:268355517696612. Epub 2017 Jan 1.
    Department of Radiology, Rajagiri Hospital, Aluva, Kerala.
    Recurrent lower limb venous insufficiency is often a challenge in clinical practice and is most commonly due to incompetent perforators. Many of these patients do not have adequate symptom relief with compression and require some form of treatment for incompetent perforator interruption. Various treatment methods have been tried with different efficiencies. Read More

    Complications of intravenous catheterization in horses.
    Schweiz Arch Tierheilkd 2017 Sep;159(9):477-485
    Equine Department, Vetsuisse Faculty, University of Zurich.
    Introduction: Intravenous catheterization is a necessity for continuous administration of intravenous fluids and for intermittent intravenous access to avoid discomfort and potential complications of repeated needle insertions into the vein. Intravenous catheterization is commonly performed and well tolerated in horses, but catheter associated complications have been reported. The most commonly reported complication is thrombophlebitis, but others such as venous air embolism, exsanguination and catheter fragmentation may also occur. Read More

    [Fibrates and risk of venous thromboembolism: Case/no-case study in French pharmacovigilance database].
    Therapie 2017 Dec 1;72(6):677-682. Epub 2017 Aug 1.
    Service de pharmacologie clinique, centre régional de pharmacovigilance de Basse Normandie, CHU Côte-de-Nacre, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France.
    Introduction: Several studies have investigated the occurrence of venous thromboembolic events (phlebitis and pulmonary embolism) [VTE] and fibrates. Fibrates could be associated with VTE although published data are contradictory. The objective of this study is to confirm the link between VTE and fibrates. Read More

    Carotid Endarterectomy in Patients With Thrombocytopenia: Analysis of the National Surgical Quality Improvement Program Registry.
    Oper Neurosurg (Hagerstown) 2017 Feb;13(1):150-156
    Background: Carotid endarterectomy (CEA) is infrequently performed in patients with mild to moderate thrombocytopenia.

    Objective: To determine whether preoperative thrombocytopenia is associated with a higher rate of complications after CEA.

    Methods: We analyzed patient characteristics, comorbid conditions, operative details, and 30-day postoperative outcomes for patients who underwent CEA in the CEA-targeted American College of Surgeons National Surgical Quality Improvement Program Registry. Read More

    Spontaneous HIT syndrome post-knee replacement surgery with delayed recovery of thrombocytopenia: a case report and literature review.
    Platelets 2017 Sep 31;28(6):614-620. Epub 2017 Aug 31.
    b Department of Pathology and Molecular Medicine, and Department of Medicine , Michael G. DeGroote School of Medicine, McMaster University , Hamilton , Ontario , Canada.
    Recently published reports have established a heparin-induced thrombocytopenia (HIT)-mimicking thromboembolic disorder without proximate heparin exposure, called spontaneous HIT syndrome. Although the pathophysiology remains unclear, anti-platelet factor 4 (PF4)/heparin antibodies possibly triggered by exposure to knee cartilage glycosaminoglycans or other non-heparin polyanions found on bacterial surfaces and nucleic acids have been postulated. We present a 53-year-old female receiving antithrombotic prophylaxis with aspirin following right total knee replacement surgery (without perioperative or any previous lifetime heparin exposure) who acutely presented with high-risk pulmonary embolism (PE) and right great saphenous vein thrombophlebitis on postoperative day (POD) 14; her platelet count at presentation was 13 × 10/L. Read More

    Early experience of transilluminated cryosurgery for varicose vein with saphenofemoral reflux: review of 84 patients (131 limbs).
    Ann Surg Treat Res 2017 Aug 28;93(2):98-102. Epub 2017 Jul 28.
    Department of Surgery, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
    Purpose: Varicose veins with great saphenous vein (GSV) insufficiency is prevalent. Among various surgical treatments for varicose veins, cryosurgery of GSV is an alternative minimally invasive technique that could leave fewer scars and replace conventional stripping with ambulatory phlebectomy. This study sought to assess outcomes including efficacy and safety of cryosurgery for varicose veins. Read More

    Pylephlebitis and Crohn's disease: A rare case of septic shock.
    Int J Surg Case Rep 2017 10;39:106-109. Epub 2017 Aug 10.
    Digestive Surgery Unit, Department of Surgery and Translational Medicine, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, Italy. Electronic address:
    Introduction: Troncular pylephlebitis, defined as septic thrombophlebitis of the portal vein, is usually secondary to suppurative infection from the regions drained by the portal system. Therefore, pylephlebitis can occur from the portal vein main tributaries. The occurrence of mesenteric pylephlebitis in Crohn's disease is extremely rare. Read More

    Diagnostic approach in persistentbacteraemia.
    BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.
    University of Texas Medical School at Houston, Houston, Texas, USA.
    is the leading cause of bacteraemia and can lead to complicated infections that may be difficult to diagnose and hence lead to higher morbidity. Failure to identify such could lead to severe complications or relapsing bacteraemia due to inadequate treatment. The authors report a patient presenting with methicillin-resistant(MRSA) bacteraemia and septic arthritis, who developed a complicated infection with multiple metastasis and persistent bacteraemia despite adequate treatment. Read More

    [Thrombotic events in patients with hemophilia].
    Ter Arkh 2017;89(7):76-84
    National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia.
    The paper describes 4 clinical cases of thrombotic events (pulmonary embolism, deep vein thrombophlebitis, acute myocardial infarction, ischemic stroke) that have occurred in patients with hemophilia. It discusses the possible causes of their development and methods for their prevention and treatment. Controlled natural hypocoagulation, in which the dose of an administered deficient factor decreases to such an extent that in order to maintain the safe level of hypocoagulation (plasma factor activity is 15-20%; activated partial thromboplastin time is 1. Read More

    Bacteraemia and liver abscess due to.
    BMJ Case Rep 2017 Jul 27;2017. Epub 2017 Jul 27.
    Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain.
    is the oropharyngeal pathogen usually associated with Lemierre's syndrome, a pharyngeal infection which evolves to sepsis, septic emboli and thrombophlebitis of the adjacent neck vessels. It is an uncommon causative bacteria of a liver abscess, and an extensive workup should, therefore, be performed in order to rule out potential sources of the infection. This case report describes the workup that led to the diagnosis of a colorectal carcinoma, which was deemed to be the source of thebacteraemia. Read More

    A case of liver abscess and fusobacterium septicemia.
    IDCases 2017 4;9:98-100. Epub 2017 Jul 4.
    Department of Medicine, Division of Infectious Diseases, Keck School of Medicine of the USC- LAC, United States.
    species are well described as the causative pathogen in Lemierre's syndrome, a suppurative thrombophlebitis of the jugular vein. However, they are less recognized for a unique variant of Lemierre's syndrome presenting with invasive intraabdominal infection and associated portal vein thrombosis. We describe a case ofwith hepatic abscess and septic pylephlebitis. Read More

    Occult Amebic Liver Abscess as Cause of Extensive Inferior Vena Cava and Hepatic Vein Thrombosis.
    Am J Trop Med Hyg 2017 Oct 19;97(4):1214-1217. Epub 2017 Jul 19.
    Population Health Research Institute, Hamilton, Ontario, Canada.
    The most common extraintestinal complication ofis amebic liver abscess (ALA). Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess. We present a case of a previously healthy 43-year-old Canadian man presenting with constitutional symptoms and right upper quadrant abdominal pain. Read More

    Neonatal Lemierre Syndrome: Youngest Reported Case and Literature Review.
    Clin Pediatr (Phila) 2018 Mar 18;57(3):294-299. Epub 2017 Jul 18.
    1 Tulane University Medical Center, New Orleans, LA, USA.
    A previously healthy 5-week-old female was admitted for sepsis secondary to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. After several days of hospitalization, she experienced acute decompensation in mental status despite having received targeted antibiotic therapy. Imaging revealed left peritonsillar/parapharyngeal space abscess, left venous thrombophlebitis of the internal jugular vein, and septic emboli of the lungs and brain consistent with Lemierre syndrome. Read More

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