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    Human Infection with Fusobacterium necrophorum without Jugular Venous Thrombosis: A Varied Presentation of Lemierre's Syndrome.
    Case Rep Infect Dis 2017 24;2017:5358095. Epub 2017 Oct 24.
    Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
    Lemierre's syndrome is also known as postangina septicemia, which is commonly caused by Fusobacterium necrophorum also known as Necrobacillus and also by other microorganisms like Staphylococcus, Streptococcus, Peptostreptococcus, and Bacteroides. Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. Read More

    Fusobacterium emphysematous pyomyositis with necrotizing fasciitis of the leg presenting as compartment syndrome: a case report.
    J Med Case Rep 2017 Nov 28;11(1):332. Epub 2017 Nov 28.
    Department of Surgery, University of Illinois at Chicago, Chicago, 60612, IL, USA.
    Background: Fusobacterium necrophorum is a common agent of disease in humans, but the occurrence of primary infections outside the head and neck area is extremely rare. While infection with Fusobacterium necrophorum has a rather benign course above the thorax, the organism is capable of producing very severe disease when located in unusual sites, including various forms of septic thrombophlebitis. No infections of the leg have been documented before; thus, antibiotic coverage for Fusobacterium is currently not recommended in this area. Read More

    [Maternal death by stroke. Results from the French enquiry into maternal deaths, 2010-2012].
    Gynecol Obstet Fertil Senol 2017 Dec 15;45(12S):S65-S70. Epub 2017 Nov 15.
    Département d'anesthésie-réanimation-SMUR, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address:
    Stroke is a rare event during pregnancy (10/100,000) and can be ischemic (24%), hemorrhagic (74%) or both (2%). Pregnancy probably increases the risk even if it is discussed for arteriovenous malformation (AVM), aneurismal subarachnoid hemorrhage (SAH) and cavernomas. Between 2010 and 2012, 31 maternal deaths were associated with stroke. Read More

    Vancomycin Infiltrate-Induced Dermatitis Mimicking Bullous Cellulitis.
    J Drugs Dermatol 2017 Nov;16(11):1160-1163

    Extravasation of medications can manifest as tenderness, pain, tissue necrosis, and thrombophlebitis and lead to infection and severe long-term complications. Risk factors for leakage of medications include mechanical and pharmacologic mechanisms such as cannulation technique, vasoconstriction, and cytotoxicity. Well-known vesicants like anthracyclines, vinca alkaloids, and vasopressors are usually administered with proper caution. Read More

    Lemierre's Syndrome - A rare cause of disseminated sepsis requiring multi-organ support.
    J Intensive Care Soc 2017 Nov 14;18(4):329-333. Epub 2017 Mar 14.
    Department of Anaesthesia, Ninewells Hospital, Dundee, UK.
    Lemierre's syndrome is a rare complication of acute pharyngitis characterised by septicaemia with infective thrombophlebitis of the internal jugular vein, most commonly due to Fusobacterium necrophorum. It characteristically affects healthy young adults causing persistent pyrexia and systemic sepsis presenting several days after an initial pharyngitis. Septic emboli seed via the bloodstream to distant sites including the lung, joints, skin, liver, spleen and brain. Read More

    Complications from Administration of Vasopressors Through Peripheral Venous Catheters: An Observational Study.
    J Emerg Med 2017 Oct 27. Epub 2017 Oct 27.
    Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
    Background: The placement of a central venous catheter for the administration of vasopressors is still recommended and required by many institutions because of concern about complications associated with peripheral administration of vasopressors.

    Objective: Our aim was to determine the incidence of complications from the administration of vasopressors through peripheral venous catheters (PVC) in patients with circulatory shock, and to identify the factors associated with these complications.

    Methods: This was a prospective, observational study conducted in the emergency department (ED) of a tertiary care medical center. Read More

    Ludwig's Angina.
    Cureus 2017 Aug 21;9(8):e1588. Epub 2017 Aug 21.
    Internal Medicine, Kettering Medical Center.
    Ludwig's angina is a diffuse cellulitis in the submandibular, sublingual, and submental spaces, characterized by its propensity to spread rapidly to the surrounding tissues. Early recognition and treatment for Ludwig's angina are of paramount importance due to the myriad of complications that can occur in association with Ludwig's angina. Known complications of Ludwig's angina include carotid arterial rupture or sheath abscess, thrombophlebitis of the internal jugular vein, mediastinitis, empyema, pericardial effusion, osteomyelitis of the mandible, subphrenic abscess, aspiration pneumonia, and pleural effusion. Read More

    Lemierre's syndrome variant of the gut.
    BMJ Case Rep 2017 Oct 20;2017. Epub 2017 Oct 20.
    Department of Internal Medicine, Washington DC VA Medical Center, Washington, D.C., USA.
    Infectious suppurative thrombophlebitis of the portal venous system, referred to as pylephlebitis, is a rare complication of intra-abdominal inflammatory processes. Advances in diagnostics and antibiotics have improved survival, but mortality remains remarkably high even in the most recent literature. The majority of patients have concomitant bacteraemia on presentation most commonly with typical gastrointestinal (GI) organisms. Read More

    Some neck swellings are serious; a case of Lemierre's Syndrome.
    J Community Hosp Intern Med Perspect 2017 Oct 19;7(4):251-254. Epub 2017 Sep 19.
    Department of Pulmonary and Critical Care, Abington Jefferson Health, Abington, PA, USA.
    Lemierre's syndrome also termed post-anginal septicemia, is a disease characterized by internal jugular septic thrombophlebitis leading to Fusobacterium septicemia with multiple metastatic foci following an oropharyngeal infection. Diagnosis and management is challenging and can result in fatal consequences due to potential multisystem involvement and multiple complications. We describe here a case of Lemierre's syndrome with multifocal pneumonia, acute renal failure and protracted course of illness over forty days with successful recovery. Read More

    Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency.
    Intern Med 2017 Oct 16. Epub 2017 Oct 16.
    Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan.
    A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed severe rectal wall thickening with partial defect of enhancement. Read More

    Potential application of immobilized streptokinase extracted from Streptococcus equinus VIT_VB2.
    Prep Biochem Biotechnol 2017 Nov 20;47(10):1032-1036. Epub 2017 Nov 20.
    a Department of Biotechnology, School of Biosciences and Technology , VIT University , Vellore , Tamil Nadu , India.
    Streptokinase purified from Streptococcus equinus VIT_VB2 isolated from bovine milk sample was immobilized in various solid supports namely entrapment in agarose gel, calcium alginate beads and gelatin gel by cross-linking with formaldehyde. Immobilization of streptokinase in calcium alginate beads showed maximum efficiency (81.8 ± 1. Read More

    Is Infection an Independent Risk Factor for Venous Thromboembolism? a Population-Based Case-Control Study.
    Am J Med 2017 Oct 4. Epub 2017 Oct 4.
    Department of Cardiovascular Diseases, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; Department Division of Hematology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; Department of Internal Medicine; and the Divisions of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
    Background: The independent association of recent infection with venous thromboembolism is uncertain. The purpose of the study was to test both overall infection (site unspecified) and specific infection sites as potential risk factors for deep vein thrombosis and pulmonary embolism adjusting for other known venous thromboembolism factors.

    Methods: Using Rochester Epidemiology Project (REP) resources, we identified all Olmsted County, MN residents with objectively-diagnosed incident deep vein thrombosis or pulmonary embolism over the 13-year period, 1988-2000 (cases; n=1303), and 1-2 residents without venous thromboembolism matched to each case on age, sex and incident venous thromboembolism date (controls; n=1494). Read More

    Lesson of the month 1: Spontaneous septic thrombophlebitis presenting with bacteraemia diagnosed by PET-CT scan.
    Clin Med (Lond) 2017 Oct;17(5):471-472
    Southend University Hospital NHS Foundation Trust, Southend, UK.
    Spontaneous septic thrombophlebitis is a rare complication of Staphylococcus aureus bacteraemia. Its true incidence is unknown as septic thrombus is not often considered as a source in the typical 'screen' of tests used to find the source of a bacteraemia.Positron emission tomography computerised tomography (PET-CT) is becoming increasingly available to physicians, is highly sensitive and yields specific anatomical information regarding abnormal metabolically active sites in infection, inflammation and neoplasia. Read More

    Treatment of incompetent perforators in recurrent venous insufficiency with adhesive embolization and sclerotherapy.
    Phlebology 2017 Jan 1:268355517696612. Epub 2017 Jan 1.
    Department of Radiology, Rajagiri Hospital, Aluva, Kerala.
    Recurrent lower limb venous insufficiency is often a challenge in clinical practice and is most commonly due to incompetent perforators. Many of these patients do not have adequate symptom relief with compression and require some form of treatment for incompetent perforator interruption. Various treatment methods have been tried with different efficiencies. Read More

    Complications of intravenous catheterization in horses.
    Schweiz Arch Tierheilkd 2017 Sep;159(9):477-485
    Equine Department, Vetsuisse Faculty, University of Zurich.
    Introduction: Intravenous catheterization is a necessity for continuous administration of intravenous fluids and for intermittent intravenous access to avoid discomfort and potential complications of repeated needle insertions into the vein. Intravenous catheterization is commonly performed and well tolerated in horses, but catheter associated complications have been reported. The most commonly reported complication is thrombophlebitis, but others such as venous air embolism, exsanguination and catheter fragmentation may also occur. Read More

    [Fibrates and risk of venous thromboembolism: Case/no-case study in French pharmacovigilance database].
    Therapie 2017 Dec 1;72(6):677-682. Epub 2017 Aug 1.
    Service de pharmacologie clinique, centre régional de pharmacovigilance de Basse Normandie, CHU Côte-de-Nacre, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France.
    Introduction: Several studies have investigated the occurrence of venous thromboembolic events (phlebitis and pulmonary embolism) [VTE] and fibrates. Fibrates could be associated with VTE although published data are contradictory. The objective of this study is to confirm the link between VTE and fibrates. Read More

    Carotid Endarterectomy in Patients With Thrombocytopenia: Analysis of the National Surgical Quality Improvement Program Registry.
    Oper Neurosurg (Hagerstown) 2017 Feb;13(1):150-156
    Background: Carotid endarterectomy (CEA) is infrequently performed in patients with mild to moderate thrombocytopenia.

    Objective: To determine whether preoperative thrombocytopenia is associated with a higher rate of complications after CEA.

    Methods: We analyzed patient characteristics, comorbid conditions, operative details, and 30-day postoperative outcomes for patients who underwent CEA in the CEA-targeted American College of Surgeons National Surgical Quality Improvement Program Registry. Read More

    Spontaneous HIT syndrome post-knee replacement surgery with delayed recovery of thrombocytopenia: a case report and literature review.
    Platelets 2017 Sep 31;28(6):614-620. Epub 2017 Aug 31.
    b Department of Pathology and Molecular Medicine, and Department of Medicine , Michael G. DeGroote School of Medicine, McMaster University , Hamilton , Ontario , Canada.
    Recently published reports have established a heparin-induced thrombocytopenia (HIT)-mimicking thromboembolic disorder without proximate heparin exposure, called spontaneous HIT syndrome. Although the pathophysiology remains unclear, anti-platelet factor 4 (PF4)/heparin antibodies possibly triggered by exposure to knee cartilage glycosaminoglycans or other non-heparin polyanions found on bacterial surfaces and nucleic acids have been postulated. We present a 53-year-old female receiving antithrombotic prophylaxis with aspirin following right total knee replacement surgery (without perioperative or any previous lifetime heparin exposure) who acutely presented with high-risk pulmonary embolism (PE) and right great saphenous vein thrombophlebitis on postoperative day (POD) 14; her platelet count at presentation was 13 × 109/L. Read More

    Early experience of transilluminated cryosurgery for varicose vein with saphenofemoral reflux: review of 84 patients (131 limbs).
    Ann Surg Treat Res 2017 Aug 28;93(2):98-102. Epub 2017 Jul 28.
    Department of Surgery, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
    Purpose: Varicose veins with great saphenous vein (GSV) insufficiency is prevalent. Among various surgical treatments for varicose veins, cryosurgery of GSV is an alternative minimally invasive technique that could leave fewer scars and replace conventional stripping with ambulatory phlebectomy. This study sought to assess outcomes including efficacy and safety of cryosurgery for varicose veins. Read More

    Pylephlebitis and Crohn's disease: A rare case of septic shock.
    Int J Surg Case Rep 2017 10;39:106-109. Epub 2017 Aug 10.
    Digestive Surgery Unit, Department of Surgery and Translational Medicine, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, Italy. Electronic address:
    Introduction: Troncular pylephlebitis, defined as septic thrombophlebitis of the portal vein, is usually secondary to suppurative infection from the regions drained by the portal system. Therefore, pylephlebitis can occur from the portal vein main tributaries. The occurrence of mesenteric pylephlebitis in Crohn's disease is extremely rare. Read More

    Diagnostic approach in persistent Staphylococcus aureus bacteraemia.
    BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.
    University of Texas Medical School at Houston, Houston, Texas, USA.
    Staphylococcus aureus is the leading cause of bacteraemia and can lead to complicated infections that may be difficult to diagnose and hence lead to higher morbidity. Failure to identify such could lead to severe complications or relapsing bacteraemia due to inadequate treatment. The authors report a patient presenting with methicillin-resistant S. Read More

    [Thrombotic events in patients with hemophilia].
    Ter Arkh 2017;89(7):76-84
    National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia.
    The paper describes 4 clinical cases of thrombotic events (pulmonary embolism, deep vein thrombophlebitis, acute myocardial infarction, ischemic stroke) that have occurred in patients with hemophilia. It discusses the possible causes of their development and methods for their prevention and treatment. Controlled natural hypocoagulation, in which the dose of an administered deficient factor decreases to such an extent that in order to maintain the safe level of hypocoagulation (plasma factor activity is 15-20%; activated partial thromboplastin time is 1. Read More

    Bacteraemia and liver abscess due to Fusobacterium necrophorum.
    BMJ Case Rep 2017 Jul 27;2017. Epub 2017 Jul 27.
    Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain.
    Fusobacterium necrophorum is the oropharyngeal pathogen usually associated with Lemierre's syndrome, a pharyngeal infection which evolves to sepsis, septic emboli and thrombophlebitis of the adjacent neck vessels. It is an uncommon causative bacteria of a liver abscess, and an extensive workup should, therefore, be performed in order to rule out potential sources of the infection. This case report describes the workup that led to the diagnosis of a colorectal carcinoma, which was deemed to be the source of the Fusobacterium bacteraemia. Read More

    A case of liver abscess and fusobacterium septicemia.
    IDCases 2017 4;9:98-100. Epub 2017 Jul 4.
    Department of Medicine, Division of Infectious Diseases, Keck School of Medicine of the USC- LAC, United States.
    Fusobacterium species are well described as the causative pathogen in Lemierre's syndrome, a suppurative thrombophlebitis of the jugular vein. However, they are less recognized for a unique variant of Lemierre's syndrome presenting with invasive intraabdominal infection and associated portal vein thrombosis. We describe a case of Fusobacterium nucleatum with hepatic abscess and septic pylephlebitis. Read More

    Occult Amebic Liver Abscess as Cause of Extensive Inferior Vena Cava and Hepatic Vein Thrombosis.
    Am J Trop Med Hyg 2017 Oct 19;97(4):1214-1217. Epub 2017 Jul 19.
    Population Health Research Institute, Hamilton, Ontario, Canada.
    The most common extraintestinal complication of Entamoeba histolytica is amebic liver abscess (ALA). Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess. We present a case of a previously healthy 43-year-old Canadian man presenting with constitutional symptoms and right upper quadrant abdominal pain. Read More

    Neonatal Lemierre Syndrome: Youngest Reported Case and Literature Review.
    Clin Pediatr (Phila) 2017 Jul 1:9922817721156. Epub 2017 Jul 1.
    1 Tulane University Medical Center, New Orleans, LA, USA.
    A previously healthy 5-week-old female was admitted for sepsis secondary to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. After several days of hospitalization, she experienced acute decompensation in mental status despite having received targeted antibiotic therapy. Imaging revealed left peritonsillar/parapharyngeal space abscess, left venous thrombophlebitis of the internal jugular vein, and septic emboli of the lungs and brain consistent with Lemierre syndrome. Read More

    Simultaneous Coexistence of Complications of Chronic Otitis Media in the Same Case.
    J Int Adv Otol 2017 Aug 17;13(2):282-284. Epub 2017 Jul 17.
    Clinic of Otorhinolaryngology/Head and Neck Surgery, Health Science University Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey.
    Chronic otitis media (COM) is a common clinical entity, but the incidence of COM complications has declined recently due to broad use of antibiotics. Independent of this, these complications are still a significant challenge in otorhinolaryngology practice because of high morbidity and mortality rates. The most common etiologic diagnosis was cholesteatomatous COM. Read More

    Marantic endocarditis and paraneoplastic pulmonary embolism.
    BMJ Case Rep 2017 Jul 14;2017. Epub 2017 Jul 14.
    Department of Internal Medicine, Hospital Garcia de Orta, Almada, Portugal.
    Cancer is frequently associated with a hypercoagulable state. Almost 15% of patients with cancer will suffer a thromboembolic event during their clinical course. The aetiology of this hypercoagulable state is multifactorial and includes procoagulant factors associated with malignancy as well as the host's inflammatory response. Read More

    The prevalence of peripheral intravenous cannulae and pattern of use: A point prevalence in a private hospital setting.
    J Clin Nurs 2017 Jul 12. Epub 2017 Jul 12.
    Cabrini-Monash University Department of Medicine, Monash University, Malvern, Vic., Australia.
    Aims And Objectives: To determine the prevalence and pattern of use of peripheral intravenous cannulae in hospital wards.

    Background: Peripheral intravenous cannulae are commonly used in acute health care to directly access the bloodstream for the administration of medications, intravenous fluids and blood products. Peripheral intravenous cannulae are associated with multiple adverse events including hospital-acquired bloodstream infection, thrombophlebitis and pain/discomfort. Read More

    [Intravenous Ablation for Lower Extremity Varices to Prevent Recurrent Pulmonary Embolism in Klippel-Trenaunay Syndrome;Report of a Case].
    Kyobu Geka 2017 Jul;70(7):504-506
    Department of Cardiovascular Surgery, Totsuka Kyoritsu Daini Hospital, Yokohama, Japan.
    Klippel-Trenaunay syndrome( KTS) is a complex congenital anomaly characterized by lower extremity varix and venous malformations, port-wine stains, and soft tissue and bone hypertrophy. We present a case of a 35-year-old man of KTS with pulmonary embolism (PE). The patient was referred to our hospital complaining of the leg pain and sudden onset of dyspnea. Read More

    Imaging of Pregnancy-related Vascular Complications.
    Radiographics 2017 Jul-Aug;37(4):1270-1289
    From the Department of Radiology, Mayo Clinic Arizona, Phoenix, Ariz (R.S.P., C.O.M.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (C.J.N., C.A.R., V.M.M., S.B.); Department of Radiology, NYU Winthrop Hospital, Mineola, NY (D.S.K.); Stony Brook University School of Medicine, Stony Brook, NY (D.S.K.); and Neuroradiology Section, Department of Radiology, Phoenix Children's Hospital, Phoenix, Ariz (P.C.).
    Pregnancy results in substantial hemodynamic and prothrombotic changes that form the foundation for downstream vascular complications, both during pregnancy and in the postpartum period. In addition, several important risk factors, including older patient age, diabetes, and smoking, can increase the risk for vascular-related pregnancy complications. Because radiologists often play an important role in evaluation of the pregnant patient, understanding the pathophysiology of vascular-related complications in pregnancy and their imaging appearances is essential for diagnostic accuracy. Read More

    Mid-term Results of Catheter Directed Foam Sclerotherapy Combined with Tumescent Local Anaesthesia for Treatment of Great Saphenous Vein Incompetence.
    Eur J Vasc Endovasc Surg 2017 Sep 29;54(3):363-368. Epub 2017 Jun 29.
    Vascular and Endovascular Surgery Department, Assiut University Hospitals, Assiut, Egypt.
    Objectives: The purpose of this prospective study was to evaluate the occlusion rate, clinical severity, disease specific health related quality of life (HRQoL), and safety in patients with great saphenous vein (GSV) reflux 3 years after a single treatment session of catheter directed foam sclerotherapy (CDFS) combined with peri-saphenous infiltration of tumescent local anaesthesia (TLA).

    Methods: A total of 249 patients with symptomatic unilateral GSV incompetence underwent CDFS combined with TLA and were followed up for 3 years. The primary outcome was complete obliteration of the treated segment of the GSV. Read More

    Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review.
    NMC Case Rep J 2016 Jul 12;3(3):53-57. Epub 2016 May 12.
    Department of Neurosurgery, Teikyo University Chiba Medical Center, Ichihara, Chiba.
    Lemierre syndrome (LS) is a rare life-threatening disease that is often caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein. LS rarely manifests as cranial nerve palsy. To the best of our knowledge, this is the second case report of LS associated with recurrent laryngeal nerve palsy. Read More

    Severe Puerperal Sepsis-A Simmering Menace.
    J Clin Diagn Res 2017 May 1;11(5):QC04-QC08. Epub 2017 May 1.
    Professor and Consultant, Department of Obstetrics and Gynecology, Vmmc and Safdarjung Hospital, New Delhi, India.
    Introduction: Even decades after the development of effective low-cost antibiotics, sepsis persists as the foremost cause of preventable maternal death worldwide. In developing countries like India, where the paramount impediment to intervention is poverty, maternal mortality due to sepsis is a continuing representation of maternal health inequality.

    Aim: To determine the incidence, risk factors and mortality in women presenting with puerperal sepsis in a tertiary care health facility in India. Read More

    Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications.
    Hum Psychopharmacol 2017 May;32(3)
    UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
    Objective: "Krokodil" is the street name for an impure homemade drug mixture used as a cheap substitute for heroin, containing desomorphine as the main opioid. Abscesses, gangrene, thrombophlebitis, limb ulceration and amputations, jaw osteonecrosis, skin discoloration, ulcers, skin infections, and bleeding are some of the typical reported signs in humans. This study aimed to understand the toxicity of krokodil using Wistar male rats as experimental model. Read More

    Necrotizing Lip Infection Causing Septic Thrombophlebitis of the Neck: A Rare Variant of Lemierre Syndrome.
    J Oral Maxillofac Surg 2017 Jun 2. Epub 2017 Jun 2.
    Head and Neck Surgeon and Oral and Maxillofacial Surgeon, Legacy Emanuel Medical Center, The Head and Neck Institute, Portland, OR.
    Lemierre syndrome is an uncommon condition in which internal jugular vein thrombosis presents after recent oropharyngeal infection. Frequently, this is accompanied by septic emboli. This report outlines a variant of this disease process, with septic thrombophlebitis of the neck associated with a necrotizing skin infection of the lower lip and chin. Read More

    The long shadow of lemierre's syndrome.
    J Infect 2017 Jun;74 Suppl 1:S47-S53
    Division of Infectious Diseases, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, Canada.
    Lemierre's syndrome is a rare and feared complication of pharyngitis, occurring most commonly in adolescents and young adults. It is typically defined by the constellation of septic internal jugular vein thrombophlebitis, pulmonary and other septic emboli, and sterilesite infection by Fusobacterium necrophorum. The rarity and severity of Lemierre's syndrome has made it an attractive subject for case reports but there is a paucity of evidence to inform areas of persistent uncertainty. Read More

    A rare case of pylephlebitis after colonic polypectomy.
    J Community Hosp Intern Med Perspect 2017 Jan 31;7(1):40-42. Epub 2017 Mar 31.
    Department of Internal Medicine, Reading Hospital & Medical Center, West Reading, PA, USA.
    Pylephlebitis or infective suppurative thrombosis of the portal mesenteric venous system is an uncommon condition that can potentially be deadly if not recognized and treated early. Although most commonly associated with pancreatitis and diverticulitis, any intra-abdominal or pelvic infection occurring in the region drained by the portal venous system can cause this rare entity. We report a case of a 75-year-old woman who developed post polypectomy pylephlebitis following colonoscopy, a condition rarely reported in the literature. Read More

    Citrobacter freundii as a cause of acute suppurative thyroiditis in an immunocompetent adult female.
    Indian J Pathol Microbiol 2017 Apr-Jun;60(2):282-284
    Department of Otorhinolaryngology, Government Medical College Hospital, Chandigarh, India.
    Acute suppurative thyroiditis (AST) is an uncommon condition, in the patients with preexisting thyroid disease or immunosuppression. The most common cause of AST is bacterial, and the most common bacteria are Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella species. Due to various complications such as septicemia, septic thrombophlebitis, necrotizing mediastinitis, or pericarditis, prompt diagnosis and treatment are the keys to reduce mortality and morbidity. Read More

    Septic Thrombophlebitis with Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia and de Novo Resistance to Vancomycin and Daptomycin.
    Infect Dis Rep 2017 May 31;9(2):7008. Epub 2017 May 31.
    Department of Medicine D, Emek Medical Center, Afula.
    Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with significant risk of mortality, especially when it occurs while on appropriate antimicrobial therapy. We herein describe an unusual case of a patient with prosthetic aortic tissue valve, who suffered from central venous catheter related MRSA bacteremia with septic thrombus formation in the superior vena cava. MRSA bacteremia persisted despite removal of the catheter and appropriate antimicrobial therapy including vancomycin, rifampin, and daptomycin. Read More

    Endoscopic electrocautery and fibrin obliteration of an acutely complicated pyriform fossa sinus tract in a septuagenarian.
    J Laryngol Otol 2017 Oct 19;131(10):933-936. Epub 2017 Jun 19.
    Department of Otolaryngology - Head and Neck Surgery,Northwick Park Hospital,London,UK.
    Background: Pyriform fossa sinus tracts classically present with neck abscess, recurrent infections and suppurative thyroiditis in children; acute presentation in a geriatric patient is rare.

    Methods: Case report and Medline literature review.

    Case Report: A 79-year-old female presented with a left-sided neck mass and severe odynophagia of 3 days' duration. Read More

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