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Rev Prat 2021 Mar;71(3):290

"Département de neuroradiologie, CHU Ibn Sina, université Mohammed V-Souissi, Rabat, Maroc".

J Orthop Case Rep 2021 Feb;11(2):95-98

Department of Orthopaedic Surgery, University of Jordan and Jordan University Hospital, Aljubeiha, Amman, Jordan.

Introduction: Prosthetic joint infection (PJI) is a rare complication of total knee replacement (TKR), yet it is a serious and debilitating condition. Bacterial infection accounts for the majority of cases and fungal infection is estimated to cause 1% of all prosthesis infection.

Case Report: This case presents a 60years female, who presented to our outpatient orthopedic clinic complaining of right knee pain, swelling, and hotness. Read More

IDCases 2021 28;25:e01173. Epub 2021 May 28.

Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

We describe a case of Lemierre's syndrome (LS) caused by a hypervirulent strain of in a 63-year-old female with hypertension, hyperlipidemia, and diabetes mellitus, who presented with right neck pain and fevers. Computerized tomography of the neck and chest revealed an occluded right internal jugular vein secondary to thrombosis and septic emboli in lungs. Blood cultures grew The patient was treated with ampicillin-sulbactam and then transitioned to amoxicillin-clavulanate to complete a 6-week course of antibiotics, and a 3-month course of rivaroxaban. Read More

Medicina (B Aires) 2021 ;81(3):454-457

Hospital Nacional Profesor Alejandro Posadas, El Palomar, Provincia de Buenos Aires, Argentina.

Phlegmasia cerulea dolens (FCD) is a rare complication of deep vein thrombosis. Its cause is unknown. The main predisposing factors for the disease are neoformative processes, hypercoagulable states, congestive heart failure, pregnancy, prolonged immobilization, and surgeries on the affected limb. Read More

Brain Nerve 2021 Jun;73(6):737-740

Department of Neurology, Kobe City Medical Center General Hospital.

A 73-year-old woman with untreated diabetes mellitus visited our emergency department with a 4-day history of progressive headache, fever, and chills. She received trigger point injections (TPI) into the right sternocleidomastoid for exercise-induced ipsilateral shoulder pain, 13 days before admission and into the right trapezius, 6 days before admission. Cerebrospinal fluid (CSF) evaluation revealed pleocytosis with a predominance of neutrophils, as well as elevated protein and reduced glucose levels. Read More

J Card Surg 2021 Jun 10. Epub 2021 Jun 10.

Department of Infectious Disease Medicine, Fukuoka Red Cross Hospital, Fukuoka, Japan.

Lemierre's syndrome (LS) is characterized by septic thrombophlebitis of the internal jugular vein with septicemia and metastatic infection following an oropharyngeal infection. LS is rare but can cause infective endocarditis (IE), complicating IE management. We report a case of IE secondary to thrombophlebitis in the left vertebral vein following pharyngitis (LS variant) with distinctively severe manifestations, including metastatic infection and severe neurological impairment with multiple cerebral infarctions. Read More

Eur Heart J Case Rep 2021 Apr 21;5(4):ytab120. Epub 2021 Apr 21.

Department of cardiology, Heart Centre OLVG, Oosterparkstraat 9, 1091 AC Amsterdam, the Netherlands.

Background: Non-bacterial thrombotic endocarditis (NBTE) is a rare form of endocarditis notably described in patients with advanced malignancy and auto-immune diseases. It is characterized by the formation of sterile, fibrin-containing vegetations on cardiac endothelium, in the absence of positive blood cultures. It is predominantly located on the mitral- and aortic valve (AV). Read More

J Vasc Surg Venous Lymphat Disord 2021 Jun 3. Epub 2021 Jun 3.

Department of Surgery, Northwest Clinics, Alkmaar, the Netherlands.

Objective: To review and analyse the currently available literature on Flebogrif and define its role in the global varicose vein treatment devices market.

Methods: A systematic literature search was performed in MEDLINE, Embase, and the Cochrane Library. Studies were eligible if they included patients treated with Flebogrif for saphenous vein incompetence, were published in English, and had full text available. Read More

Cureus 2021 Apr 27;13(4):e14713. Epub 2021 Apr 27.

Internal Medicine, AdventHealth Florida, Sebring, USA.

Lemierre's syndrome is a condition in which an oropharyngeal infection progresses to sepsis and thrombophlebitis of the internal jugular vein. Although the incidence of this syndrome has fallen dramatically since the widespread use of antibiotic therapy to treat streptococcal pharyngitis, it should still be suspected in otherwise healthy young patients presenting with the triad of prolonged pharyngitis, lateral neck pain, and septic symptoms. In this report, we explore a unique case of Lemierre's syndrome complicated by hypercoagulability and ineffective initial antibiotic therapy. Read More

Phlebology 2021 May 27:2683555211015564. Epub 2021 May 27.

Division of Vascular Surgery, University of British Columbia, Vancouver, BC, Canada.

Objective: The use of cyanoacrylate products (CA) in incompetent perforator vein (IPV) treatment has not been thoroughly examined. The primary objective of this study is to describe the technique of ultra sound guided direct injection of IPV with CA, and secondarily to determine early closure rates and safety of this technique.

Methods: A retrospective analysis of patients undergoing IPV injection at two centres between 2015-2018 was conducted. Read More

J Pediatric Infect Dis Soc 2021 May 26. Epub 2021 May 26.

Department of Pediatrics, Division of Infectious Diseases, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Although Fusobacterium necrophorum is well described as an emerging pathogen of acute mastoiditis in young children, infection with other anaerobes can lead to similar severe sequelae including intracranial and extracranial suppurative thrombophlebitis and sepsis. We describe a patient whose unremarkable exposure history assumed increased significance upon obtaining the results of 16S next generation sequencing from a surgical specimen. The novel pathogen Bacteroides pyogenes is reviewed herein. Read More

Minerva Med 2021 05 14. Epub 2021 May 14.

Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland.

Lemierre syndrome is a rare form of septic thrombophlebitis of the head and neck veins, most typically the internal jugular vein, which affects otherwise healthy adolescents and young adults after an oropharyngitis or other local infection and is characterized by multiple septic embolization. Despite treatment, Lemierre syndrome displays a high rate of in-hospital complications that include thrombus progression and new peripheral septic embolization, and it can be fatal or cause disabling sequelae. The mainstay of treatment is antibiotic therapy; anticoagulation is often used, but its role is controversial. Read More

Semin Thromb Hemost 2021 May 10. Epub 2021 May 10.

Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Isolated distal deep vein thrombosis (IDDVT) is presumed to be more benign than proximal DVT (PDVT) or pulmonary embolism (PE), suggesting a need for different management approaches. This subgroup analysis of the RE-COVERY DVT/PE global, observational study investigated patient characteristics, hospitalization details, and anticoagulant therapy in patients with IDDVT in real-world settings in 34 countries enrolled from January 2016 to May 2017. Data were analyzed descriptively according to the type and location of the index venous thromboembolism (VTE): IDDVT, PDVT ± distal DVT (DDVT), and PE ± DVT. Read More

Pract Neurol 2021 May 7. Epub 2021 May 7.

Department of Neurology, Leeds Centre for Neurosciences, Leeds General Infirmary, Leeds, West Yorkshire, UK.

Lemierre's syndrome is a rare and potentially life-threatening condition that follows an oropharyngeal infection, typically from and usually affects healthy adolescents or young adults. The characteristic features are septic thrombophlebitis of the internal jugular vein and septic embolism leading to multiorgan involvement, commonly the brain, lungs and bones. We report a man with presenting symptoms suggesting hemicrania continua, whose initial imaging showed no features of dural venous sinus or jugular thrombosis. Read More

Proc (Bayl Univ Med Cent) 2021 Jan 12;34(3):387-388. Epub 2021 Jan 12.

Department of Internal Medicine, Creighton University, Omaha, Nebraska.

Lemierre's syndrome is a rare disorder characterized by thrombophlebitis of the internal jugular vein and is caused by gram-negative anaerobes, primarily . We report a case of a 20-year-old man who developed chronic osteomyelitis of the femur and myonecrosis of thigh muscles secondary to this syndrome. The diagnosis was made based on clinical presentation and evidence of thrombosis in the internal jugular vein on ultrasound. Read More

Arch Endocrinol Metab 2021 Apr 29. Epub 2021 Apr 29.

Departamento de Nutrologia e Diabetes, Universidade Federal do Rio de Janeiro, RJ, Brasil.

Objective: Adipose tissue-derived stromal/stem cells (ASCs) and vitamin D have immunomodulatory actions that could be useful for type 1 diabetes (T1D). We aimed in this study to investigate the safety and efficacy of ASCs + daily cholecalciferol (VIT D) for 6 months in patients with recent-onset T1D.

Methods: In this prospective, dual-center, open trial, patients with recent onset T1D received one dose of allogenic ASC (1 × 10 cells/kg) and cholecalciferol 2,000 UI/day for 6 months (group 1). Read More

Zhonghua Wai Ke Za Zhi 2021 May;59(5):366-369

Department of Vascular Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

To examine the long-term efficacy of radiofrequency closure in the treatment of great saphenous vein varicose. The clinic data of 185 patients with varicose veins of lower limbs treated with radiofrequency closure admitted at Department of Vascular Surgery, Beijing Shijitan Hospital, Capital Medical University from July 2016 to January 2017 was analyzed retrospectively. A total of 203 limbs were treated by radiofrequency closure. Read More

Case Rep Crit Care 2021 9;2021:5544505. Epub 2021 Apr 9.

Staten Island University Hospital, Staten Island, NY 10305, USA.

Background: Central venous catheters (CVCs) have been frequently associated with septic thrombophlebitis, bacteremia, and septic emboli. Right-sided infective endocarditis is seen concurrently in patients with septic pulmonary emboli. A case of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and septic pulmonary emboli secondary to infected peripheral venous catheter (PVC) is reported. Read More

Ann Med Surg (Lond) 2021 Apr 31;64:102267. Epub 2021 Mar 31.

Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

Background: Extravasation injury (EVI) is common, yet it is always underestimated and underreported. Severity varies ranging from thrombophlebitis up to disability. Unrecognised EVI is a potential medicolegal case in medicine. Read More

BMJ Case Rep 2021 Apr 22;14(4). Epub 2021 Apr 22.

Internal Medicine, John H Stroger Hospital of Cook County, Chicago, Illinois, USA.

The authors present a case of a 42-year-old previously healthy man who presented in sepsis, with right lateral gaze palsy. He was found to have bilateral cavernous sinus thrombosis (CST) and bilateral internal jugular thrombosis in the setting of bacteraemia. The patient was successfully treated and recovered from his illness after a protracted stay in the medical intensive care unit. Read More

J Vasc Access 2021 Apr 16:11297298211009019. Epub 2021 Apr 16.

Beaumont Hospital, Royal Oak, MI, USA.

Objective: Thrombophlebitis associated with peripheral intravenous catheters (PIVCs) is a poorly described complication in the literature. Given limited accuracy of current assessment tools and poor documentation in the medical record, the true incidence and relevance of this complication is misrepresented. We aimed to identify risk factors in the development of thrombophlebitis using an objective methodology coupling serial diagnostic ultrasound and clinical assessment. Read More

IDCases 2021 24;24:e01074. Epub 2021 Mar 24.

Department of Otolaryngology, Head and Neck Surgery, Kurashiki Central Hospital, Japan.

J Thromb Haemost 2021 Apr 8. Epub 2021 Apr 8.

Department of Medicine, Centre Hospitalier de l'Université de Sherbrooke, Sherbrooke, Quebec, Canada.

Background: Pelvic vein thrombosis (PVT) is a rare complication of pregnancy that can lead to life-threatening complications, such as pulmonary embolism (PE).

Objective: To describe characteristics of PVT and its treatment in pregnancy in the province of Quebec, Canada.

Patients/methods: We developed a province-wide case series of PVT in pregnancy including four tertiary care centers and the Registry of Rare Diseases of the Groupe d'Étude en Médecine Obstétricale du Québec. Read More

Vasc Med 2021 Apr 8:1358863X211000420. Epub 2021 Apr 8.

Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland.

Mondor disease is characterized by an acute painful thrombophlebitis occurring at specific anatomical sites. Data on its incidence, characteristics of clinical presentation, and course are unavailable to date. We studied the course of Mondor disease in patients diagnosed and followed at the University Hospital Zurich (Switzerland) between 2004 and 2020. Read More

Acta Ophthalmol 2021 Apr 8. Epub 2021 Apr 8.

Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland.

Purpose: Lemierre syndrome is a life-threatening condition characterized by head/neck bacterial infection, local suppurative thrombophlebitis and septic embolic complications in a range of sites of distant organs. No prior study focused on the course and characteristics of ophthalmic complications of Lemierre syndrome.

Methods: We analysed data of 27 patients with ophthalmic complications from a large cohort of 712 cases with Lemierre syndrome reported globally between 2000 and 2017. Read More

Medeni Med J 2021 26;36(1):58-62. Epub 2021 Mar 26.

Bahçeşehir University School of Medicine, Department of Radiology, Istanbul, Turkey.

Lemierre's syndrome is an illness characterized by internal jugular vein thrombophlebitis related to infectious agents, primarily Fusobacterium necrophorum. These bacteria, residing in both the oropharynx and the gastrointestinal tract, may lead to pylephlebitis, a serious condition that could result in the development of hepatic abscesses. This manifestation of the disease is regarded as the abdominal variant of Lemierre's syndrome. Read More

J Med Case Rep 2021 Apr 2;15(1):188. Epub 2021 Apr 2.

Surgery Department, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.

Background: Mondor's disease of the breast (MDB) is a rare and benign disorder of the breast. It is characterized by thrombophlebitis of the superficial veins of the chest wall. Clinically, it manifests as a cord-like induration of the breast area. Read More

Laryngorhinootologie 2021 04 30;100(4):291-293. Epub 2021 Mar 30.

Department of Radiology, University Hospital Gießen, Gießen, Germany.

J Am Coll Health 2021 Mar 24:1-5. Epub 2021 Mar 24.

Division of Ambulatory Care, Department of Emergency Medicine, West Virginia University, Morgantown, West Virginia, USA.

Familiarity breeds complacency. One case of sore throat can start to sound like another. However, even common viral and bacterial infections can lead to serious sequelae. Read More

Cureus 2021 Feb 18;13(2):e13421. Epub 2021 Feb 18.

Breast Surgery, West Hertfordshire Hospitals NHS Trust, St. Albans, GBR.

Mondor's disease is a rare, peculiar form of superficial thrombophlebitis which mainly affects the subcutaneous veins of the breast, anterior chest wall, neck, axilla, upper limbs and penis. In most cases, it presents with rapid development of a painful subcutaneous cord-like structure that later becomes less painful, but a fibrous band persists. Unfortunately, aetiology and management are not very clear, but it is a self-limiting condition in most cases. Read More