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Ned Tijdschr Geneeskd 2022 05 18;166. Epub 2022 May 18.

Martini Ziekenhuis, afd. Interne Geneeskunde, Groningen.

Background: Lemierre's syndrome is a rare disease with different clinical and microbiological criteria. Without adequate treatment mortality is high. It often concerns healthy adolescents who present with common and usually harmless complaints such as fever and sore throat. Read More

Acta Clin Croat 2021 Dec;60(4):773-776

1Department of Anesthesiology and Intensive Therapy, Slovenj Gradec General Hospital, Slovenj Gradec, Slovenia; 2Department of Gynecology and Obstetrics, Slovenj Gradec General Hospital, Slovenj Gradec, Slovenia.

Deep septic pelvic thrombophlebitis is a rare but potentially devastating complication in the puerperium. Early diagnosis and aggressive treatment of this postpartum complication is essential. We report a case of a 23-year-old multipara, who presented with persistent high fever and abdominal pain two days after delivery. Read More

Exp Ther Med 2022 Jul 17;24(1):449. Epub 2022 May 17.

Clinic of Dermatology, County Emergency Hospital of Sibiu, 550245 Sibiu, Romania.

The role of hyperhomocysteinemia (HH) in the etiopathogenetics of systemic thrombotic events has been confirmed by numerous studies. However, it has been insufficiently studied as an etiopathogenic factor in chronic venous insufficiency (CVI). The present prospective study included 166 patients with CVI at stages C3-C6. Read More

Cureus 2022 May 16;14(5):e25034. Epub 2022 May 16.

Clinical Neurosciences, University of the East Ramon Magsaysay Memorial Medical Center, Quezon City, PHL.

Cavernous sinus thrombophlebitis is a rare, potentially life-threatening, condition that is most often caused by gram-negative bacteria and, to a lesser extent, fungi. is an opportunistic fungus that frequently affects patients with a weak immune system. We describe a case of an adult female without diabetes who developed sphenoid sinusitis causing cavernous sinus thrombophlebitis. Read More

Radiol Case Rep 2022 Aug 13;17(8):2883-2887. Epub 2022 Jun 13.

Division of Radiology, Detroit Receiving Hospital/University Health Network 3L8, 4201 St Antoine Blvd, Detroit, MI 48201, USA.

On December 2020, the US Food and Drug Administration issued the first emergency use authorization for a vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report development of superficial thrombophlebitis in the ipsilateral breast of a 43-year-old female 7 days after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine. Given that this is the first case of superficial thrombophlebitis in the breast shortly after mRNA vaccination for COVID-19 reported to our knowledge, we suggest that this may be a rare vaccine-related event. Read More

J Antimicrob Chemother 2022 Jun 13. Epub 2022 Jun 13.

Hospices Civils de Lyon, Service des maladies infectieuses et tropicales, Hôpital de la Croix-Rousse, Lyon, Auvergne-Rhône-Alpes, France.

Background: Necrotizing external otitis (NEO) is a severe infection of the skull base that occurs generally in the elderly and/or in diabetic recipients. There are few data in the literature about the therapeutic management of this complex bone infection.

Objectives: To analyse relapses after NEO treatment completion, and to describe the clinical features of NEO. Read More

Transplant Proc 2022 Jun 7. Epub 2022 Jun 7.

Department of Gastrointestinal Surgery and Liver Transplantation, Clinical Hospital of the Federal University of Paraná, Curitiba, PR, Brazil; Department of General Surgery, Clinical Hospital of the Federal University of Paraná, Curitiba, PR, Brazil.

Lemierre syndrome is a rare complication of oropharyngeal infection, especially acute pharyngotonsillitis, associated with septicemia and thrombophlebitis of the internal jugular vein (IJV). We present the case of a 52-year-old patient who underwent liver transplantation and returned with symptoms of pain, redness and left cervical bulging 1 month after surgery. After investigation, the diagnosis of septic thrombophlebitis of the IJV was made. Read More

Balkan Med J 2022 Jun 8. Epub 2022 Jun 8.

Clinic of Internal Medicine, Medical University of Graz, Graz, Austria.

Case Rep Med 2022 28;2022:8522398. Epub 2022 May 28.

Faculty of Medicine Osijek, University J.J. Strossmayera Osijek, J.Huttlera 4, Osijek, Croatia.

Lemierre's syndrome refers to the septic thrombophlebitis of the internal jugular vein. The condition typically begins with an oropharyngeal infection and frequently involves inflammation within the wall of the vein, infected thrombus within the lumen, surrounding soft tissue inflammation, persistent bacteremia, and septic emboli. Lemierre's syndrome is a rare disease; it occurs most commonly in otherwise healthy young adults. Read More

Injury 2022 Jul 20;53(7):2650-2656. Epub 2022 May 20.

CHU de Poitiers, 2 rue de la Milétrie, Service d'Orthopédie-Traumatologie et Chirurgie de la Colonne, 86021 Poitiers, France.

Tibial plateau fracture is a frequent entity for which surgical management is difficult both surgically and postoperatively, with multiple complications and often delayed recovery. The challenge lies in the anatomical reduction of the joint, the limitation of complications and the rapid functional recovery. Tuberoplasty appears to be an innovative technique that meets current expectations. Read More

Ann R Coll Surg Engl 2022 May 31. Epub 2022 May 31.

Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris Descartes University, France.

Penile Mondor's disease (PMD), or thrombosis of the dorsal vein, is an under-reported benign condition. Its aetiology is poorly understood. Clinically, it presents as a palpable cord in the dorsal vein of the penis, with pain or local discomfort, especially during erection. Read More

Cir Cir 2022 ;90(3):427-428

CB-Xpert Laboratorio de Patología Clínica, Miahuatlán de Porfirio Díaz, Oaxaca. México.

Breast Dis 2022 ;41(1):273-278

Division of Hospital Medicine, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, Japan.

Background: Mondor disease is superficial thrombophlebitis of the thoracoabdominal wall, mid-upper arm, and penis. Although it is usually a benign disease requiring no specific treatment, little is known about this disease owing to its rarity.

Objective: The aim of this retrospective observational study was to investigate the epidemiology and prognosis of Mondor disease. Read More

Toxins (Basel) 2022 05 13;14(5). Epub 2022 May 13.

Department of Veterinary Clinics and Surgery, Veterinary College, Federal University of Minas Gerais, Belo Horizonte 30123-970, MG, Brazil.

Bites of brown spiders ( spp.) are responsible for dermonecrotic lesions and potentially systemic envenoming that can lead to death. The only effective therapy is the use of the antivenom, usually produced in horses. Read More

J Vasc Access 2022 May 24:11297298221095778. Epub 2022 May 24.

Department of Infective Diseases, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Introduction: Although several guidelines recommend that prolonged administration of vancomycin should be preferably carried out by a central venous access, vancomycin is often given peripherally. Whether such risk may be affected by different modalities of administration in terms of dilution and time of infusion, it is a matter of controversy.

Methods: This single-center prospective study enrolled all consecutive patients requiring prolonged intravenous infusion of vancomycin (1 g/day) using long peripheral cannula "mini-midline. Read More

J Belg Soc Radiol 2022 4;106(1):38. Epub 2022 May 4.

Hopital de la citadelle - Liège, BE.

Lemierre syndrome is a rare complication of bacterial pharyngitis with cervical thrombophlebitis leading to pulmonary abcesses; the radiologist may have a key role. Read More

J Belg Soc Radiol 2022 27;106(1):24. Epub 2022 Apr 27.

Presbyterian Medical Center, KR.

Radiologists need to be familiar with that ovarian vein thrombosis can occur as a complication of urinary tract infection. Ovarian vein thrombosis is a rare disease in which a majority of cases occur during the postpartum period. There are few case reports for ovarian vein thrombosis associated with urinary tract infection in non-postpartum women. Read More

Turk J Anaesthesiol Reanim 2022 Apr;50(2):145-147

Claude Bernard Lyon University Faculty of Medicine, Lyon, France; Department of Anaesthesiology and Reanimation, Centre Hospitalier Lyon-Sud, Hospice Civil de Lyon, Lyon, France.

Septic thrombophlebitis requires both adapted antimicrobial therapy and control of the source of the infection. The source of the infection is generally controlled through adequate management of anticoagulation. In this study, we present the case of a 50 years old woman, with septic thrombophlebitis of a peripherally inserted central catheters line and with persistent bacteremia and thrombus, where in situ thrombolysis has successfully removed the thrombus. Read More

J Vasc Access 2022 May 7:11297298221095287. Epub 2022 May 7.

Vascular Access Consulting, LLC, East Henderson, KY, USA.

Background: Multimodal research and guidelines recognize veins in the forearm used for peripheral intravenous catheter (PIVC) insertion can optimize dwell time. Yet, many PIVCs are still placed in areas of flexion or suboptimal locations such as the back of the hand causing premature failure of >50%. This study identified characteristics of the forearm cephalic vein that make the anatomical location highly successful for PIVC insertion. Read More

Open Forum Infect Dis 2022 May 18;9(5):ofac143. Epub 2022 Apr 18.

Division of Infectious Disease, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Lemierre's syndrome (LS) is a rare and potentially fatal condition that predominantly affects young adults with oropharyngeal infection. is the usual etiology and classically causes internal jugular vein septic thrombophlebitis, frequently complicated by septic emboli to several organs (most classically to the lungs). Lemierre-like syndrome (LLS) describes the same constellation of symptoms and pathophysiology as Lemierre's syndrome; however, spp. Read More

J Radiol Case Rep 2022 Mar 1;16(3):1-14. Epub 2022 Mar 1.

Department of Radiology, National Hospital Organization/Osaka National Hospital, Osaka, Japan.

Septic thrombi, such as those observed in pylephlebitis and Lemierre's syndrome, are characterized by portal vein thrombosis and venous thrombosis with bacterial infection. Although radiographic findings of septic thrombus on contrast-enhanced computed tomography have been well described, no report has described the characteristics of non-contrast-enhanced computed tomography. We describe a case series of septic thrombophlebitis exhibiting intravascular hypo- and hyper-attenuation on non-contrast-enhanced computed tomography. Read More

Respir Med Case Rep 2022 18;37:101651. Epub 2022 Apr 18.

Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

is an anaerobe that is commensal to the human oral cavity. It is usually a component of periodontal plaque that is emerging as a pathogen and quickly attracting attention of the medical and research communities. It has been even discovered in bronchoalveolar lavage of some patients with lung cancer. Read More

West Afr J Med 2022 Apr;39(4):425-428

Department of Surgery, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria.

Background: Mondor's disease (MD) is a rare cause of chest pain, characterized by thrombophlebitis of the subcutaneous veins of the anterolateral thoracoabdominal wall. It is a benign, self-limiting condition that is often underdiagnosed due to lack of knowledge of the condition. Although the exact aetiology is unclear, several predisposing factors, including excessive physical activity have been postulated. Read More

Pediatr Emerg Care 2022 Apr 27. Epub 2022 Apr 27.

Pediatric Emergency Medicine, Medical University of South Carolina, Charleston, SC.

Septic thrombophlebitis represents a rare but serious collection of diseases, which carry a high risk of morbidity and mortality requiring prompt and aggressive treatment. Diagnosis centers on identification of thrombus along with clinical and microbiologic data. We present a case where point-of-care ultrasound was used to diagnose septic thrombophlebitis of the internal jugular vein and expedite appropriate therapy. Read More

Cureus 2022 Mar 23;14(3):e23420. Epub 2022 Mar 23.

Department of Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.

Lemierre's syndrome is a rare disease that generally occurs in young, healthy individuals, where an index of suspicion for something so serious is often low. There is no standardized definition of Lemierre's syndrome, which has led to a dilemma if Lemierre's can be diagnosed without internal jugular vein (IJV) thrombophlebitis. We highlight a complex case of Lemierre's syndrome that deviates from the classical presentation of the disease. Read More

Diagnostics (Basel) 2022 Apr 8;12(4). Epub 2022 Apr 8.

School of Medicine, Chang Gung University, Taoyuan 333, Taiwan.

Deep neck infection (DNI) is a severe disease affecting the deep neck spaces, and is associated with an increased risk of airway obstruction. Lemierre's syndrome (LS) refers to septic thrombophlebitis of the internal jugular vein after pharyngeal infection, and is linked with high morbidity and mortality. Both diseases begin with an oropharyngeal infection, and concurrence is possible. Read More

J Dermatol 2022 Apr 17. Epub 2022 Apr 17.

Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan.

Behçet's disease (BD) has a heterogeneous spectrum of disease manifestations featuring the involvement of different organs and can be characterized with different symptoms depending on the clinical department in charge. We retrospectively reviewed BD patients seen at our hospital and investigated the presence of neutrophils producing neutrophil extracellular traps (NET) in those patients. Immunolabeling of myeloperoxidase and histone citrullination proteins was performed on skin biopsies from three BD patients who had skin biopsy-proven superficial vein thrombophlebitis in their erythema nodosum-like lesions. Read More

Vasa 2022 May 13;51(3):182-189. Epub 2022 Apr 13.

Department of Angiology, University Hospital Zurich, Switzerland.

Treatment of pelvic venous disorders (PVD) including pelvic congestion syndrome (PCS) are often delayed due to its varying clinical manifestations. Patient referral was based on a literature- and personal experience-derived clinical "PCS screening score" (higher score points indicate greater likelihood with a maximum score of 10 points). We studied consecutive women who were (i) referred for vascular assessment and treatment to the University Hospital Zurich (2017-2021), (ii) had a PCS score ≥3 points, (iii) had evidence of obstructive or non-obstructive PVD by duplex sonography or cross-sectional imaging, and (iv) underwent endovascular therapy. Read More

BMC Urol 2022 Apr 12;22(1):57. Epub 2022 Apr 12.

Morphological Sciences Department, Institute of Medical Sciences, Medical College of Rzeszow University, Leszka Czarnego 4, 35-301, Rzeszow, Poland.

Background: Penile Mondor disease is a superficial dorsal vein thrombophlebitis of the penis, which mainly affects young and middle-aged men. It generally manifests as a visible painful cord located along the dorsal surface of the penis with signs of skin inflammation. The condition is usually self-limiting, but in severe cases a surgical procedure may be necessary in addition to pharmacological treatment. Read More

Eur J Case Rep Intern Med 2022 23;9(3):003258. Epub 2022 Mar 23.

Urology Department, Royal Hobart Hospital, Hobart, Tasmania, Australia.

Penile Mondor's disease is a rare condition characterised by superficial thrombophlebitis of the penis which is usually self-limiting. The cause is often unknown. The AstraZeneca ChAdOx1-S vaccine has been found to cause a hypercoagulable state, which is well documented. Read More