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    1 OF 475

    Diagnostic approach in persistent Staphylococcus aureus bacteraemia.
    BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.
    University of Texas Medical School at Houston, Houston, Texas, USA.
    Staphylococcus aureus is the leading cause of bacteraemia and can lead to complicated infections that may be difficult to diagnose and hence lead to higher morbidity. Failure to identify such could lead to severe complications or relapsing bacteraemia due to inadequate treatment. The authors report a patient presenting with methicillin-resistant S. Read More

    [Thrombotic events in patients with hemophilia].
    Ter Arkh 2017 ;89(7):76-84
    National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia.
    The paper describes 4 clinical cases of thrombotic events (pulmonary embolism, deep vein thrombophlebitis, acute myocardial infarction, ischemic stroke) that have occurred in patients with hemophilia. It discusses the possible causes of their development and methods for their prevention and treatment. Controlled natural hypocoagulation, in which the dose of an administered deficient factor decreases to such an extent that in order to maintain the safe level of hypocoagulation (plasma factor activity is 15-20%; activated partial thromboplastin time is 1. Read More

    Bacteraemia and liver abscess due to Fusobacterium necrophorum.
    BMJ Case Rep 2017 Jul 27;2017. Epub 2017 Jul 27.
    Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain.
    Fusobacterium necrophorum is the oropharyngeal pathogen usually associated with Lemierre's syndrome, a pharyngeal infection which evolves to sepsis, septic emboli and thrombophlebitis of the adjacent neck vessels. It is an uncommon causative bacteria of a liver abscess, and an extensive workup should, therefore, be performed in order to rule out potential sources of the infection. This case report describes the workup that led to the diagnosis of a colorectal carcinoma, which was deemed to be the source of the Fusobacterium bacteraemia. Read More

    A case of liver abscess and fusobacterium septicemia.
    IDCases 2017 4;9:98-100. Epub 2017 Jul 4.
    Department of Medicine, Division of Infectious Diseases, Keck School of Medicine of the USC- LAC, United States.
    Fusobacterium species are well described as the causative pathogen in Lemierre's syndrome, a suppurative thrombophlebitis of the jugular vein. However, they are less recognized for a unique variant of Lemierre's syndrome presenting with invasive intraabdominal infection and associated portal vein thrombosis. We describe a case of Fusobacterium nucleatum with hepatic abscess and septic pylephlebitis. Read More

    Occult Amoebic Liver Abscess as Cause of Extensive Inferior Vena Cava and Hepatic Vein Thrombosis.
    Am J Trop Med Hyg 2017 Jul 3. Epub 2017 Jul 3.
    Population Health Research Institute, Hamilton, Ontario, Canada.
    The most common extraintestinal complication of Entamoeba histolytica is amoebic liver abscess (ALA). Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess. We present a case of a previously healthy 43-year-old Canadian man presenting with constitutional symptoms and right upper quadrant abdominal pain. Read More

    Neonatal Lemierre Syndrome: Youngest Reported Case and Literature Review.
    Clin Pediatr (Phila) 2017 Jul 1:9922817721156. Epub 2017 Jul 1.
    1 Tulane University Medical Center, New Orleans, LA, USA.
    A previously healthy 5-week-old female was admitted for sepsis secondary to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. After several days of hospitalization, she experienced acute decompensation in mental status despite having received targeted antibiotic therapy. Imaging revealed left peritonsillar/parapharyngeal space abscess, left venous thrombophlebitis of the internal jugular vein, and septic emboli of the lungs and brain consistent with Lemierre syndrome. Read More

    Simultaneous Coexistence of Complications of Chronic Otitis Media in the Same Case.
    J Int Adv Otol 2017 Aug 17;13(2):282-284. Epub 2017 Jul 17.
    Clinic of Otorhinolaryngology/Head and Neck Surgery, Health Science University Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey.
    Chronic otitis media (COM) is a common clinical entity, but the incidence of COM complications has declined recently due to broad use of antibiotics. Independent of this, these complications are still a significant challenge in otorhinolaryngology practice because of high morbidity and mortality rates. The most common etiologic diagnosis was cholesteatomatous COM. Read More

    Marantic endocarditis and paraneoplastic pulmonary embolism.
    BMJ Case Rep 2017 Jul 14;2017. Epub 2017 Jul 14.
    Department of Internal Medicine, Hospital Garcia de Orta, Almada, Portugal.
    Cancer is frequently associated with a hypercoagulable state. Almost 15% of patients with cancer will suffer a thromboembolic event during their clinical course. The aetiology of this hypercoagulable state is multifactorial and includes procoagulant factors associated with malignancy as well as the host's inflammatory response. Read More

    The prevalence of peripheral intravenous cannulae and pattern of use: A point prevalence in a private hospital setting.
    J Clin Nurs 2017 Jul 12. Epub 2017 Jul 12.
    Cabrini-Monash University Department of Medicine, Monash University, 154 Wattletree Road, Malvern, VIC 3144, Australia.
    Aims And Objectives: to determine the prevalence and pattern of use of peripheral intravenous cannula (PIVC) in hospital wards.

    Background: PIVC are commonly used in acute health care to directly access the bloodstream for the administration of medications, intravenous fluids (IVF) and blood products. PIVC are associated with multiple adverse events including hospital acquired bloodstream infection, thrombophlebitis, and pain/discomfort. Read More

    [Intravenous Ablation for Lower Extremity Varices to Prevent Recurrent Pulmonary Embolism in Klippel-Trenaunay Syndrome;Report of a Case].
    Kyobu Geka 2017 Jul;70(7):504-506
    Department of Cardiovascular Surgery, Totsuka Kyoritsu Daini Hospital, Yokohama, Japan.
    Klippel-Trenaunay syndrome( KTS) is a complex congenital anomaly characterized by lower extremity varix and venous malformations, port-wine stains, and soft tissue and bone hypertrophy. We present a case of a 35-year-old man of KTS with pulmonary embolism (PE). The patient was referred to our hospital complaining of the leg pain and sudden onset of dyspnea. Read More

    Imaging of Pregnancy-related Vascular Complications.
    Radiographics 2017 Jul-Aug;37(4):1270-1289
    From the Department of Radiology, Mayo Clinic Arizona, Phoenix, Ariz (R.S.P., C.O.M.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (C.J.N., C.A.R., V.M.M., S.B.); Department of Radiology, NYU Winthrop Hospital, Mineola, NY (D.S.K.); Stony Brook University School of Medicine, Stony Brook, NY (D.S.K.); and Neuroradiology Section, Department of Radiology, Phoenix Children's Hospital, Phoenix, Ariz (P.C.).
    Pregnancy results in substantial hemodynamic and prothrombotic changes that form the foundation for downstream vascular complications, both during pregnancy and in the postpartum period. In addition, several important risk factors, including older patient age, diabetes, and smoking, can increase the risk for vascular-related pregnancy complications. Because radiologists often play an important role in evaluation of the pregnant patient, understanding the pathophysiology of vascular-related complications in pregnancy and their imaging appearances is essential for diagnostic accuracy. Read More

    Mid-term Results of Catheter Directed Foam Sclerotherapy Combined with Tumescent Local Anaesthesia for Treatment of Great Saphenous Vein Incompetence.
    Eur J Vasc Endovasc Surg 2017 Jun 29. Epub 2017 Jun 29.
    Vascular and Endovascular Surgery Department, Assiut University Hospitals, Assiut, Egypt.
    Objectives: The purpose of this prospective study was to evaluate the occlusion rate, clinical severity, disease specific health related quality of life (HRQoL), and safety in patients with great saphenous vein (GSV) reflux 3 years after a single treatment session of catheter directed foam sclerotherapy (CDFS) combined with peri-saphenous infiltration of tumescent local anaesthesia (TLA).

    Methods: A total of 249 patients with symptomatic unilateral GSV incompetence underwent CDFS combined with TLA and were followed up for 3 years. The primary outcome was complete obliteration of the treated segment of the GSV. Read More

    Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review.
    NMC Case Rep J 2016 Jul 12;3(3):53-57. Epub 2016 May 12.
    Department of Neurosurgery, Teikyo University Chiba Medical Center, Ichihara, Chiba.
    Lemierre syndrome (LS) is a rare life-threatening disease that is often caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein. LS rarely manifests as cranial nerve palsy. To the best of our knowledge, this is the second case report of LS associated with recurrent laryngeal nerve palsy. Read More

    Severe Puerperal Sepsis-A Simmering Menace.
    J Clin Diagn Res 2017 May 1;11(5):QC04-QC08. Epub 2017 May 1.
    Professor and Consultant, Department of Obstetrics and Gynecology, Vmmc and Safdarjung Hospital, New Delhi, India.
    Introduction: Even decades after the development of effective low-cost antibiotics, sepsis persists as the foremost cause of preventable maternal death worldwide. In developing countries like India, where the paramount impediment to intervention is poverty, maternal mortality due to sepsis is a continuing representation of maternal health inequality.

    Aim: To determine the incidence, risk factors and mortality in women presenting with puerperal sepsis in a tertiary care health facility in India. Read More

    Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications.
    Hum Psychopharmacol 2017 May;32(3)
    UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
    Objective: "Krokodil" is the street name for an impure homemade drug mixture used as a cheap substitute for heroin, containing desomorphine as the main opioid. Abscesses, gangrene, thrombophlebitis, limb ulceration and amputations, jaw osteonecrosis, skin discoloration, ulcers, skin infections, and bleeding are some of the typical reported signs in humans. This study aimed to understand the toxicity of krokodil using Wistar male rats as experimental model. Read More

    Necrotizing Lip Infection Causing Septic Thrombophlebitis of the Neck: A Rare Variant of Lemierre Syndrome.
    J Oral Maxillofac Surg 2017 Jun 2. Epub 2017 Jun 2.
    Head and Neck Surgeon and Oral and Maxillofacial Surgeon, Legacy Emanuel Medical Center, The Head and Neck Institute, Portland, OR.
    Lemierre syndrome is an uncommon condition in which internal jugular vein thrombosis presents after recent oropharyngeal infection. Frequently, this is accompanied by septic emboli. This report outlines a variant of this disease process, with septic thrombophlebitis of the neck associated with a necrotizing skin infection of the lower lip and chin. Read More

    The long shadow of lemierre's syndrome.
    J Infect 2017 Jun;74 Suppl 1:S47-S53
    Division of Infectious Diseases, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, Canada.
    Lemierre's syndrome is a rare and feared complication of pharyngitis, occurring most commonly in adolescents and young adults. It is typically defined by the constellation of septic internal jugular vein thrombophlebitis, pulmonary and other septic emboli, and sterilesite infection by Fusobacterium necrophorum. The rarity and severity of Lemierre's syndrome has made it an attractive subject for case reports but there is a paucity of evidence to inform areas of persistent uncertainty. Read More

    A rare case of pylephlebitis after colonic polypectomy.
    J Community Hosp Intern Med Perspect 2017 Jan 31;7(1):40-42. Epub 2017 Mar 31.
    Department of Internal Medicine, Reading Hospital & Medical Center, West Reading, PA, USA.
    Pylephlebitis or infective suppurative thrombosis of the portal mesenteric venous system is an uncommon condition that can potentially be deadly if not recognized and treated early. Although most commonly associated with pancreatitis and diverticulitis, any intra-abdominal or pelvic infection occurring in the region drained by the portal venous system can cause this rare entity. We report a case of a 75-year-old woman who developed post polypectomy pylephlebitis following colonoscopy, a condition rarely reported in the literature. Read More

    Citrobacter freundii as a cause of acute suppurative thyroiditis in an immunocompetent adult female.
    Indian J Pathol Microbiol 2017 Apr-Jun;60(2):282-284
    Department of Otorhinolaryngology, Government Medical College Hospital, Chandigarh, India.
    Acute suppurative thyroiditis (AST) is an uncommon condition, in the patients with preexisting thyroid disease or immunosuppression. The most common cause of AST is bacterial, and the most common bacteria are Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella species. Due to various complications such as septicemia, septic thrombophlebitis, necrotizing mediastinitis, or pericarditis, prompt diagnosis and treatment are the keys to reduce mortality and morbidity. Read More

    Septic Thrombophlebitis with Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia and de Novo Resistance to Vancomycin and Daptomycin.
    Infect Dis Rep 2017 May 31;9(2):7008. Epub 2017 May 31.
    Department of Medicine D, Emek Medical Center, Afula.
    Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with significant risk of mortality, especially when it occurs while on appropriate antimicrobial therapy. We herein describe an unusual case of a patient with prosthetic aortic tissue valve, who suffered from central venous catheter related MRSA bacteremia with septic thrombus formation in the superior vena cava. MRSA bacteremia persisted despite removal of the catheter and appropriate antimicrobial therapy including vancomycin, rifampin, and daptomycin. Read More

    Endoscopic electrocautery and fibrin obliteration of an acutely complicated pyriform fossa sinus tract in a septuagenarian.
    J Laryngol Otol 2017 Jun 19:1-4. Epub 2017 Jun 19.
    Department of Otolaryngology - Head and Neck Surgery,Northwick Park Hospital,London,UK.
    Background: Pyriform fossa sinus tracts classically present with neck abscess, recurrent infections and suppurative thyroiditis in children; acute presentation in a geriatric patient is rare.

    Methods: Case report and Medline literature review.

    Case Report: A 79-year-old female presented with a left-sided neck mass and severe odynophagia of 3 days' duration. Read More

    [Diagnostic workup and therapy of acute venous diseases].
    Hautarzt 2017 Aug;68(8):595-602
    Phlebologie, Universitäts-Hautklinik Tübingen, Liebermeisterstr. 25, 72076, Tübingen, Deutschland.
    Acute venous diseases, especially deep leg and pelvic vein thrombosis, present an angiological emergency and can lead to acute life-threatening events such as pulmonary embolism. Long-term consequences may be postthrombotic syndromes. In addition to stroke and myocardial infarction, deep leg and pelvic vein thrombosis are one of the most common cardiovascular diseases. Read More

    Septic thrombophlebitis of the internal jugular vein, a case of Lemierre's syndrome.
    Intractable Rare Dis Res 2017 May;6(2):137-140
    Oak Hill Hospital, Graduate Medical Education, Department of Internal Medicine, Brooksville, FL, USA.
    An 18-year-old gentleman with a history of recurrent tonsillitis presented to the emergency room complaining of worsening sore throat. He was found to have a peritonisillar abscess, and imaging revealed a non-occlusive left internal jugular vein thrombosis. Lemierre's syndrome is a rare, potentially fatal condition characterized by internal jugular vein thrombosis with septicemia following an acute oropharyngeal infection. Read More

    Clinical Presentation and Risk Factors of Venous Thromboembolic Disease.
    Crit Care Nurs Q 2017 Jul/Sep;40(3):201-209
    Division of Pulmonary and Critical Care Medicine (Drs Alhassan, Gandhi, Naddour, Singh, and Bihler) and Department of Medicine (Dr Pelinescu), Allegheny General Hospital, Pittsburgh, Pennsylvania.
    Venous thromboembolism (VTE) has a wide range of clinical presentations. Deep venous thrombosis may occur in upper or lower extremities or in visceral veins. Extremity deep venous thrombosis usually manifests with unilateral painful swelling in the limb, while visceral deep venous thrombosis manifestations vary on the basis of the involved organ. Read More

    Case Report: Behçet's disease accompanied with vitiligo.
    F1000Res 2017 23;6:310. Epub 2017 Mar 23.
    Dermatology Department, Kayseri Training and Research Hospital, Kayseri, 38050, Turkey.
    Recently, a few case reports and clinical studies have been published that explore the association of Behçet's Disease (BD) and vitiligo, with conflicting results. Genetic and immunological properties of BD and presence of autoantibodies support autoimmunity, but clinical features suggest autoinflammatory diseases. BD is thought to be a cornerstone between autoimmune and autoinflammatory diseases. Read More

    A Study of Morbidity and Cost of Peripheral Venous Cannulation in Neonates Admitted to Paediatric Surgical Intensive Care Unit.
    J Clin Diagn Res 2017 Mar 1;11(3):UC08-UC10. Epub 2017 Mar 1.
    Professor and Head, Department of Paediatric Surgery, Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.
    Introduction: Peripheral venous access in sick neonates is indicated for administration of fluids, drugs or nutrients.

    Aim: We conducted an audit of peripheral venous access in neonates admitted to paediatric surgical intensive care unit to study the morbidity, time spent on cannulation and cost with its use.

    Materials And Methods: One hundred consecutive neonates requiring hospital admission to paediatric surgical intensive care unit in a period of one year were included in the study. Read More

    Lemierre's syndrome; a rare cause of septic arthritis.
    BMJ Case Rep 2017 May 12;2017. Epub 2017 May 12.
    Musgrove Park Hospital, Taunton, UK.
    Lemierre's syndrome is a rare condition characterised by pharyngitis leading to septic thrombophlebitis of the internal jugular vein. Complications include pulmonary septic emboli, septic arthritis and disseminated intravascular coagulation. The authors present a case of a healthy woman aged 25 years with septic arthritis of the shoulder due to this unusual cause. Read More

    [Bilateral papilledema].
    J Fr Ophtalmol 2017 May 6;40(5):422-429. Epub 2017 May 6.
    Service d'ophtalmologie, CHU de Bordeaux, place Amelie-Raba-Léon, 33000 Bordeaux, France; Inserm, U1219, Bordeaux Population Health Research Center, 33000 Bordeaux, France. Electronic address:
    This article will review the current standard of care in the diagnosis and management of bilateral optic disc edema. Two emergent conditions must be considered first: secondary intracranial hypertension (cerebral tumor, cerebral thrombophlebitis…) and arteritic ischemic optic neuropathy (or giant cell arteritis). Having ruled out these two diagnoses, the management follows various steps in order to: (i) rule out pseudo-edema, and (ii) determine the underlying cause of the edema: papilledema, non-arteritic ischemic optic neuropathy or papillitis. Read More

    Pathogen-related factors affecting outcome of catheter-related bacteremia due to methicillin-susceptible Staphylococcus aureus in a Spanish multicenter study.
    Eur J Clin Microbiol Infect Dis 2017 May 5. Epub 2017 May 5.
    Department of Microbiology, University Hospital 12 de Octubre, Instituto de Investigación Hospital "12 de Octubre" (i+12), Universidad Complutense, Madrid, Spain.
    Even with appropriate clinical management, complicated methicillin-susceptible Staphylococcus aureus (MSSA) catheter-related bacteremia (CRB) is frequent. We investigated the influence of molecular characteristics of MSSA strains on the risk of complicated bacteremia (CB) in MSSA-CRB. A multicenter prospective study was conducted in Spain between 2011 and 2014 on MSSA-CRB. Read More

    Complication Rates of 3% Hypertonic Saline Infusion Through Peripheral Intravenous Access.
    J Neurosci Nurs 2017 Jun;49(3):191-195
    Stephen A. Figueroa, MD, Division of Neurocritical Care, Departments of Neurosurgery and Neurology & Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX.
    Introduction: Hyperosmolar therapy with hypertonic saline (HTS) is a cornerstone in the management of intracranial hypertension and hyponatremia in the neurological intensive care unit. Theoretical safety concerns remain for infiltration, thrombophlebitis, tissue ischemia, and venous thrombosis associated with continuous 3% HTS administered via peripheral intravenous (pIV) catheters. It is common practice at many institutions to allow only central venous catheter infusion of 3% HTS. Read More

    Effect and safety of early weight-bearing on the outcome after open-wedge high tibial osteotomy: a systematic review and meta-analysis.
    Arch Orthop Trauma Surg 2017 Jul 25;137(7):903-911. Epub 2017 Apr 25.
    Department of Orthopaedic Surgery, Seoul National University School of Medicine, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-Si, Gyeonggi-do, 463-707, South Korea.
    Introduction: The purpose of this systematic review and meta-analysis was to evaluate the effectiveness and safety of early weight-bearing by comparing clinical and radiological outcomes between early and traditional delayed weight-bearing after OWHTO.

    Materials And Methods: A rigorous and systematic approach was used. The methodological quality was also assessed. Read More

    Dangerous Liaisons: Pelvic Variant of Lemierre Syndrome by Right Common Iliac Vein Thrombophlebitis After Sexual Intercourse.
    J Low Genit Tract Dis 2017 Jul;21(3):e37-e39
    1CHU Toulouse, Department of Obstetrics and Gynecology, Hôpital Paule de Viguier, Toulouse, France; 2CHU Toulouse, Department of Gynecological Surgery, Hôpital Rangueil, Toulouse, France; 3Université Paul Sabatier, Toulouse, France; and 4CHU Toulouse, Department of Infectious and Tropical Diseases, Purpan University Hospital, Toulouse, France.

    A Comprehensive Approach to Hepatic Vascular Disease.
    Radiographics 2017 May-Jun;37(3):813-836. Epub 2017 Apr 21.
    From the Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, 1400 Pressler St, Houston, TX 77030 (K.M.E., S.J.); Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah (A.M.S.); Department of Diagnostic and Interventional Imaging, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Tex (S.M.R.); Department of Diagnostic Radiology, University of Miami Health System, Miami, Fla (B.L.M., R.P.C., V.J.C.); and Department of Diagnostic Radiology, Mayo Clinic, Scottsdale, Ariz (C.O.M.).
    The liver has a complex vascular supply, which involves the inflow of oxygenated blood through the hepatic artery (systemic circulation) and deoxygenated blood through the portal vein (portal circulation), as well as the outflow of deoxygenated blood through the hepatic veins to the inferior vena cava. A spectrum of vascular variants can involve the liver. Some of these variants may result in areas of enhancement that can mimic more serious pathologic conditions. Read More

    Oesophageal cancer presenting as Lemierre's syndrome caused by Streptococcus anginosus.
    BMJ Case Rep 2017 Apr 17;2017. Epub 2017 Apr 17.
    Hurley Medical Center, Flint, Michigan, USA
    A 59-year-old man presented to the emergency department with complaints of dysphagia, right-sided neck swelling, fever and chills. Physical examination was remarkable for fever and tender swelling over the right side of the neck. Laboratory investigations revealed leucocytosis with neutrophilia. Read More

    Risk Factors in Children Older Than 5 Years With Pneumococcal Meningitis: Data From a National Network.
    Pediatr Infect Dis J 2017 May;36(5):457-461
    From the *Urgences pédiatriques, CHU Nantes, Hôpital Mère-Enfant, 44093 Nantes, France; †ACTIV, Association Clinique et Thérapeutique Infantile du Val de Marne, 94100 Saint-Maur des Fossés, France; ‡Université Paris Est, IMRB-GRC GEMINI, 94000 Créteil, France; §Unité Court Séjour, Petits Nourrissons, Service de Néonatologie, Centre Hospitalier Intercommunal de Créteil, 94000 Créteil, France; ¶Laboratoire de génétique humaine des maladies infectieuses, institut national de la santé et de la recherche médicale, UMR1163, Institut IMAGINE, 75015 Paris, France; ‖Faculté de médecine de Necker, Université Paris V René-Descartes, 75015 Paris, France; **Centre d'études des déficits immunitaires (CEDI), AP-HP, hôpital Necker-Enfants-Malades, 75015 Paris, France; ††Centre National de Référence des Pneumocoques, AP-HP, HEGP (Hôpital Européen Georges Pompidou), Université Paris V, 75006 Paris, France; and ‡‡Pédiatrie générale, CHU Nantes, Hôpital Mère-Enfant, 44093 Nantes, France.
    Background: The occurrence of meningitis in children >5 years old may be associated with specific predisposing factors that can be anatomic, such as cerebrospinal fluid fistula or breach, or related to genetic susceptibility or N inborn or acquired immunologic defect. This study aimed to assess the anatomical and immunologic risk factors in children >5 years old with pneumococcal meningitis and prospectively enrolled in the French national meningitis network.

    Methods: We analyzed all data for children who were 5-15 years old with a diagnosis of pneumococcal meningitis between 2001 and 2013. Read More

    Paraoxonase and Arylesterase Levels in Behcet's Disease and Their Relations with the Disease Activity.
    Biochem Genet 2017 Aug 7;55(4):335-344. Epub 2017 Apr 7.
    Department of Biochemistry, Medical Faculty, Ataturk University, Erzurum, Turkey.
    The aim of this study was to determine the paraoxonase (PON) and arylesterase (ARE) enzyme activity levels in Behcet's disease (BD) and to investigate whether they are associated with the disease activity. Twenty-six patients (study group) with active BD and 28 healthy controls (control group) were included in this study. While the patients who had at least one of the symptoms related to genital ulcer, skin lesions, active uveitis, arthritis, thrombophlebitis, or central nervous system involvement in addition to oral ulcers were considered as the active group, the patients who did not show clinical symptoms in the last one month due to the medical treatment were considered as the inactive group in the clinical evaluation of patients with BD. Read More

    Utility of the Ginza forceps for superficial phlebectomy during endovenous laser ablation of the great saphenous vein.
    Surg Today 2017 Apr 7. Epub 2017 Apr 7.
    Division of Vascular Surgery, Department of Surgery, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
    Purpose: To evaluate the efficiency of using the Ginza forceps (DVx, Tokyo, Japan), which have a long shaft and strong grip, for superficial phlebectomy with the stab avulsion technique, during simultaneous endovenous laser ablation (EVLA) of the great saphenous vein (GSV).

    Methods: The subjects were patients treated with EVLA performed by a single operator at one institution. All patients had a GSV diameter of 4-10 mm and an EVLA length of the GSV of >20 cm. Read More

    Safety and efficacy of a novel drug elores (ceftriaxone+sulbactam+disodium edetate) in the management of multi-drug resistant bacterial infections in tertiary care centers: a post-marketing surveillance study.
    Braz J Infect Dis 2017 Jul - Aug;21(4):408-417. Epub 2017 Apr 1.
    Venus Remedies, Department of Clinical Research, Panchkula, India.
    Objective: In India, Elores (CSE-1034: ceftriaxone+sulbactam+disodium edetate) was approved as a broad spectrum antibiotic in year 2011 and is used for management of Extended Spectrum Beta Lactamases/Metallo Beta lactamases infections in tertiary care centers. The objective of this study was to investigate the efficacy of this drug in patients with Extended Spectrum Beta Lactamases/Metallo Beta lactamases infections and identify the incidence of adverse events in real clinical settings.

    Methods: This Post Marketing Surveillance study was conducted at 17 centers across India and included 2500 patients of all age groups suffering from various bacterial infections and treated with Elores (CSE1034). Read More

    Chromobacterium violaceum infection in chronic granulomatous disease: a case report and review of the literature.
    JMM Case Rep 2017 Jan 31;4(1):e005084. Epub 2017 Jan 31.
    Department of Infectious Diseases, Austin Health, Heidelberg, VIC 3084, Australia; Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
    Introduction.Chromobacterium violaceum is an opportunistic human pathogen, associated with significant mortality, and has been reported in patients with chronic granulomatous disease (CGD), a genetic condition causing impaired phagocytosis. Case presentation. Read More

    Lemierre's Syndrome Associated with Mechanical Ventilation and Profound Deafness.
    Case Rep Infect Dis 2017 26;2017:4261429. Epub 2017 Feb 26.
    Department of Internal Medicine, Ev. Krankenhaus Witten gGmbH, University of Witten/Herdecke, Pferdebachstr 27, 58455 Witten, Germany.
    Lemierre's syndrome is a rare disorder that is characterized by anaerobic organisms inducing a thrombophlebitis of the internal jugular vein (IJV) following a course of oropharyngeal infection. It often occurs in young and healthy patients. Clinicians continuously misinterpret early symptoms until infection disseminates systematically and life-threatening sepsis transpires. Read More

    Surgical treatment of osteoporotic thoraco-lumbar compressive fractures: the use of pedicle screw with augmentation PMMA.
    Eur Spine J 2017 Mar 21. Epub 2017 Mar 21.
    Spine Surgery, AOU Città della Salute e della Scienza di Torino, Via Zuretti 29, 10126, Turin, Italy.
    Introduction: The osteoporosis prevalence in population is age related. The aim of this single-center observational study was evaluate the middle- to long-term performance of cement (PMMA) augmented fenestrated pedicle screws in elderly patients with thoraco-lumbar compressive fractures by osteoporosis.

    Materials And Methods: From 2011 to 2015 we treated 52 patients (20 males and 32 females) suffering from somatic osteoporotic fractures (T10-L2). Read More

    Long-term risk of venous thromboembolism recurrence after isolated superficial vein thrombosis.
    J Thromb Haemost 2017 Jun 5;15(6):1123-1131. Epub 2017 May 5.
    Department of Public Health, University Grenoble Alpes, CNRS, Grenoble University Hospital and, TIMC-IMAG, Grenoble, France.
    Essentials Long-term risk of recurrence of isolated superficial vein thrombosis (SVT) is under-studied. We analyzed data from a cohort of first SVT and proximal deep vein thrombosis (DVT) without cancer. The risk of recurrence as DVT or pulmonary embolism is twice lower in SVT patients. Read More

    Asymptomatic Urolithiasis Complicated by Nephrocutaneous Fistula.
    J Clin Imaging Sci 2017 20;7. Epub 2017 Feb 20.
    Department of Imaging and Medical Information Sciences, Service of Radiology, University Hospitals of Geneva, Genève, Switzerland.
    Asymptomatic spontaneous nephrocutaneous fistula is a rare and severe complication of chronic urolithiasis. We report a case of 56-year-old woman with a nephrocutaneous fistula (NFC) which developed from a superinfected urinoma following calyceal rupture due to an obstructing calculus in the left ureter. The patient was clinically asymptomatic and came to the emergency department for a painless left flank fluctuating mass. Read More

    [Clinical and therapeutic aspects of post-partum cerebral thrombophlebites].
    Pan Afr Med J 2016 21;25:248. Epub 2016 Dec 21.
    Service de Gynécologie Obstétrique- CHU Ibn El Jazzar, Kairouan, Tunisie.
    Cerebral thrombophlebites are rare but life-threatening conditions (1/5000 births). Pregnancy and postpartum are predisposing factors: clinical presentation vary and may be misleading, dominated by headaches, convulsions and neurological deficits but showing no specific features. Physical examination often generates informations unavailable and misleading because cerebral thrombophlebites share symptoms with other affections. Read More

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