19,709 results match your criteria Thoracic Aortic Aneurysm


Identification of circumferential regional heterogeneity of ascending thoracic aneurysmal aorta by biaxial mechanical testing.

J Mol Cell Cardiol 2019 Apr 15. Epub 2019 Apr 15.

Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT, Via Tricomi n.5, 90127 Palermo, Italy.

Ascending thoracic aortic aneurysm (ATAA) in patients with bicuspid aortic valve (BAV) can present an asymmetrical aortic dilatation compared with patients with tricuspid aortic valve (TAV). This pattern of aneurysm dilatation led us to hypothesize that biomechanical differences likely induced by regional heterogeneity of material properties can underlie the observed asymmetric enlargement discrepancies between BAV ATAA and TAV ATAA. This study aimed to characterize the mechanical properties and associated aortic tissue stiffness changes along the circumferential direction of aortic rings collected from surgically-repaired patients with ATAA. Read More

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http://dx.doi.org/10.1016/j.yjmcc.2019.04.010DOI Listing
April 2019
1 Read

[Extra-anatomical bypass grafting of the thoracic aorta in a female patient with an infected pseudoaneurysm].

Angiol Sosud Khir 2019 ;25(1):169-174

Department of Aorta and Coronary Arteries Surgery, National Medical Research Centre named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.

Presented herein is the remote (more than 15-year follow up) result of successful surgical treatment of aortic coarctation complicated by septic aortitis and a false aneurysm of the anastomosis between the graft and the aortic arch. In 2002, after correction of aortic coarctation the woman was admitted to our Clinic with an incompetent proximal anastomosis and an infected aortic pseudoaneurysm. Taking into consideration the general and local septic process, repeat reconstruction of the thoracic aorta was impossible due to the risk for generalization of the infectious process and fatal complications. Read More

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http://dx.doi.org/10.33529/angio2019123DOI Listing
January 2019
2 Reads

[Hibrid surgical treatment of an aortic arch aneurysm].

Angiol Sosud Khir 2019 ;25(1):164-167

Research Department of Vascular and Interventional Surgery, Research Laboratory of Vascular and Hybrid Surgery, National Medical Research Centre named after V.A. Almazov under the RF Ministry of Public Health, Saint Petersburg, Russia.

Presented in the article is a clinical case report regarding hybrid surgical management of a saccular aneurysm of the aortic arch: simultaneous right-left-carotid-left-subclavian bypass grafting and endovascular isolation of the aneurysm. Taking into consideration the findings of multislice computed tomography-aortography (MSCT aortography) prior to surgery, the anatomical location of the aneurysm with the involvement of the ostium of the left subclavian artery, close location of the proximal branches of the aortic arch at an acute angle relative to each other required performing simultaneous debranching in order to enlarge the proximal zone of fixation of a stent graft at the level of the brachiocephalic trunk (BCT). The postoperative period proved uneventful, with as rapid rehabilitation as possible. Read More

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https://elibrary.ru/item.asp?id=37004679
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http://dx.doi.org/10.33529/angio2019122DOI Listing
January 2019
2 Reads

Microbiomes of Inflammatory Thoracic Aortic Aneurysms Due to Giant Cell Arteritis and Clinically Isolated Aortitis Differ From Those of Non-Inflammatory Aneurysms.

Pathog Immun 2019 15;4(1):105-123. Epub 2019 Mar 15.

Genomic Medicine Institute; Lerner Research Institute; Cleveland Clinic; Cleveland, Ohio.

Objective: We sought to characterize microbiomes of thoracic aortas from patients with non-infectious aortitis due to giant cell arteritis (GCA) and clinically isolated aortitis (CIA) and to compare them to non-inflammatory aorta aneurysm controls. We also compared microbiomes from concurrently processed and separately reported temporal arteries (TA) and aortas.

Methods: From 220 prospectively enrolled patients undergoing surgery for thoracic aorta aneurysm, 49 were selected. Read More

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http://dx.doi.org/10.20411/pai.v4i1.269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438704PMC
March 2019
1 Read

Is there a role for autophagy in ascending aortopathy associated with tricuspid or bicuspid aortic valve?

Clin Sci (Lond) 2019 Apr 2;133(7):805-819. Epub 2019 Apr 2.

Department of Translational Medical Sciences, Università degli Studi della Campania 'L. Vanvitelli', Naples, Italy.

Autophagy is a conserved process by which cytoplasmatic elements are sequestered in vesicles and degraded after their fusion with lysosomes, thus recycling the precursor molecules. The autophagy-mediated removal of redundant/harmful/damaged organelles and biomolecules plays not only a replenishing function, but protects against stressful conditions through an adaptive mechanism. Autophagy, known to play a role in several pathological conditions, is now gaining increasing attention also in the perspective of the identification of the pathogenetic mechanisms at the basis of ascending thoracic aortic aneurysm (TAA), a localized or diffused dilatation of the aorta with an abnormal widening greater than 50 percent of the vessel's normal diameter. Read More

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http://dx.doi.org/10.1042/CS20181092DOI Listing
April 2019
1 Read

Long noncoding RNA myocardial infarction associated transcript promotes the development of thoracic aortic by targeting microRNA-145 via the PI3K/Akt signaling pathway.

J Cell Biochem 2019 Apr 15. Epub 2019 Apr 15.

Department of Vascular Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, China.

The main aim of our study was to investigate the roles and molecular basis of long noncoding RNA myocardial infarction associated transcript (MIAT) in the development of thoracic aortic aneurysm. RT-qPCR assay was performed to measure the expressions of MIAT, microRNA-145 (miR-145), along with Bcl-2 and Bcl-xl messenger RNAs. Western blot assay was conducted to determine protein levels of Bcl-2, Bcl-xl, phosphorylated-Akt (p-Akt), and total Akt (t-Akt). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.28695
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http://dx.doi.org/10.1002/jcb.28695DOI Listing
April 2019
2 Reads

Contemporary Management of Aortic Arch Aneurysm.

Semin Thorac Cardiovasc Surg 2019 Apr 10. Epub 2019 Apr 10.

Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). Electronic address:

Background: The management of the aortic arch aneurysm is becoming increasingly complex and multidisciplinary. It has evolved since the first successful repair by DeBakey and colleagues in 1957. After these initial repairs, the improvement in open surgical techniques, cardiopulmonary bypass, anesthesia, and perioperative care were the primary drivers of the decrease in morbidity and mortality associated with repair. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2019.03.011DOI Listing
April 2019
3 Reads

Characteristic Cerebrovascular Findings Associated with ACTA2 Gene Mutations.

Can J Neurol Sci 2019 Apr 12:1-2. Epub 2019 Apr 12.

From theDepartment of Radiology,University of Michigan,Ann Arbor, Michigan,USA.

A specific mutation (Arg179) of the ACTA2 gene has previously been described to cause a syndrome of multisystemic smooth muscle dysfunction with an extremely characteristic cerebrovascular appearance.1 Accurate neuroimaging diagnosis of this entity is important as this syndrome predisposes to complications such as early-onset ischemic stroke and ascending thoracic aortic aneurysm.2,3 The following case demonstrates a previously undescribed ACTA2 mutation (Met46) with an identical cerebrovascular imaging appearance to that of Arg179 mutations, but a less severe overall phenotype. Read More

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http://dx.doi.org/10.1017/cjn.2019.20DOI Listing
April 2019
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Thoracic Aortic Aneurysm Growth in Bicuspid Aortic Valve Patients: Role of Aortic Stiffness and Pulsatile Hemodynamics.

J Am Heart Assoc 2019 Apr;8(8):e010885

3 Division of Cardiology University of Ottawa Heart Institute Ottawa Ontario Canada.

Background Bicuspid aortic valve ( BAV ) is the most common congenital cardiac abnormality. A thoracic aortic aneurysm ( TAA ) is present in ≈50% of BAV patients, who also have an 8-fold higher risk of aortic dissection than the general population. Because the health of the aorta is directly reflected in its stiffness and pulsatile hemodynamics, we hypothesized that measures of aortic stiffness and arterial load would be associated with TAA growth in BAV . Read More

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http://dx.doi.org/10.1161/JAHA.118.010885DOI Listing
April 2019
1 Read

External suture annuloplasty for mild to moderate and moderate aortic regurgitation due to an isolated type Ic lesion.

Gen Thorac Cardiovasc Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Cardiac Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Objective: Whether mild to moderate and moderate aortic regurgitation should be corrected surgically during other cardiovascular surgeries remains controversial. We evaluated the effectiveness of external suture annuloplasty in such cases.

Methods: Among 95 patients undergoing aortic valve repair between December 2013 and March 2018, five patients with mild to moderate and moderate aortic regurgitation due to aortic annulus dilatation (type Ic lesion) underwent surgery for mitral regurgitation and/or thoracic aortic aneurysm. Read More

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http://dx.doi.org/10.1007/s11748-019-01119-1DOI Listing
April 2019
1 Read

Wall Stress and Geometry Measures in Electively Repaired Abdominal Aortic Aneurysms.

Ann Biomed Eng 2019 Apr 8. Epub 2019 Apr 8.

Department of Mechanical Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.

Abdominal aortic aneurysm (AAA) is a vascular disease characterized by the enlargement of the infrarenal segment of the aorta. A ruptured AAA can cause internal bleeding and carries a high mortality rate, which is why the clinical management of the disease is focused on preventing aneurysm rupture. AAA rupture risk is estimated by the change in maximum diameter over time (i. Read More

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http://dx.doi.org/10.1007/s10439-019-02261-wDOI Listing
April 2019
1 Read

Biallelic variants in SMAD6 are associated with a complex cardiovascular phenotype.

Hum Genet 2019 Apr 8. Epub 2019 Apr 8.

Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Rare heterozygous variants in SMAD6 have been identified as a significant genetic contributor to bicuspid aortic valve-associated thoracic aortic aneurysm on one hand and non-syndromic midline craniosynostosis on the other. In this study, we report two individuals with biallelic missense variants in SMAD6 and a complex cardiac phenotype. Trio exome sequencing in Proband 1, a male who had aortic isthmus stenosis, revealed the homozygous SMAD6 variant p. Read More

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http://dx.doi.org/10.1007/s00439-019-02011-xDOI Listing
April 2019
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Compressed Amplatzer Vascular Plug II Embolization of the Left Subclavian Artery for Thoracic Endovascular Aortic Repair is Efficient and Safety Method Comparable to Conventional Coil Embolization.

Yonago Acta Med 2019 Mar 28;62(1):24-29. Epub 2019 Mar 28.

||Division of Organ Regeneration Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.

Background: Left subclavian artery (LSA) embolization is occasionally required to prevent type II endoleak in the thoracic endovascular aortic repair (TEVAR) procedure. This is a retrospective study comparing compressed Amplatzer Vascular Plug II embolization (CAE) and conventional coil embolization (CCE) in preventing retrograde flow into the aneurysmal sac through the LSA after TEVAR.

Methods: We retrospectively reviewed the records of patients who underwent CAE or CCE of the LSA during TEVAR from June 2013 to March 2016 in our hospital. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437410PMC
March 2019
4 Reads

Commentary: Surgical repair of thoracoabdominal aortic aneurysm-Still room for improvement.

J Thorac Cardiovasc Surg 2019 Feb 27. Epub 2019 Feb 27.

Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2019.02.053DOI Listing
February 2019
2 Reads

Simplified frozen elephant trunk technique for combined open and endovascular treatment of extensive aortic diseases.

Eur J Cardiothorac Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Cardiovascular Surgery, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany.

Objectives: This study aims to analyse the impact of a simplified frozen elephant trunk (FET) technique on early outcome.

Methods: Between October 2010 and August 2018, 92 consecutive patients (mean age 64.4 ± 12. Read More

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http://dx.doi.org/10.1093/ejcts/ezz082DOI Listing
April 2019
7 Reads

Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease.

J Am Heart Assoc 2019 Apr;8(8):e011671

2 Division of Cardiothoracic Surgery Michael E. DeBakey Department of Surgery Baylor College of Medicine Houston TX.

Background Thoracic aortic aneurysm ( TAA ) and dissection ( TAD ) are characterized by progressive disorganization of the aortic wall matrix, including elastin, a highly immunogenic molecule. Whether acquired autoimmune responses can be detected in TAA / TAD patients who are smokers is unknown. The objectives of this study were to determine whether TAA / TAD smokers have increased T-cell responses to human elastin fragments, and to determine whether autoimmune responses in TAA / TAD smokers are dependent on chronic obstructive pulmonary disease. Read More

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http://dx.doi.org/10.1161/JAHA.118.011671DOI Listing
April 2019
7 Reads
2.882 Impact Factor

Novel approach to prevention of perioperative stroke in patients undergoing debranching thoracic endovascular aortic repair with mini-cardiopulmonary bypass support.

Ann Vasc Surg 2019 Apr 4. Epub 2019 Apr 4.

Department of Cardiovascular Surgery, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

Objective: Perioperative stroke is a major complication after debranching thoracic endovascular aortic repair (TEVAR), with a reported incidence of 7.0% to 26.9%. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.09.036DOI Listing

A patient with T4 esophageal cancer cured by radical resection combined with an aortic arch aneurysm, coronary heart disease, hypertension, diabetes, and other high-risk factors.

Panminerva Med 2019 Apr 3. Epub 2019 Apr 3.

Department of Thoracic Surgery/Huiqiao Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou, China -

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http://dx.doi.org/10.23736/S0031-0808.19.03622-XDOI Listing
April 2019
2 Reads

Long-term stroke incidence in proximal thoracic aorta aneurysm survivors.

Int J Stroke 2019 Apr 2:1747493019840944. Epub 2019 Apr 2.

1 Department of Neurology, Buddhist Tzu Chi General Hospital, Hualien.

Background: Aneurysm of proximal thoracic aorta (pTAA) is an often indolent, yet fatal disease. Although advancements in aneurysmal repair techniques have increased long-term survival rates, studies have proven that there are increases in perioperative risk for stroke incidence after pTAA surgery. Conversely, there is little evidence regarding the long-term stroke incidence in pTAA individuals, which strongly influences the morbidity, mortality, and usage of antithrombotic agents. Read More

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http://dx.doi.org/10.1177/1747493019840944DOI Listing
April 2019
3 Reads

Gender differences on mortality and re-interventions after TEVAR for intact aneurysms of the thoracic aorta.

Int Angiol 2019 Apr 1. Epub 2019 Apr 1.

Departament of Surgery and Physiology, Faculty of Medicine of Porto, Porto, Portugal.

Introduction: Thoracic endovascular aortic repair (TEVAR) has been increasingly adopted in the treatment of intact thoracic aorta aneurysms (iTAA), offering a less invasive approach with good effectiveness. Women usually present with smaller aorta's, while having greater aneurysm growth rates. How sex can affect mortality and re- interventions after TEVAR for iTAA is the aim of this review. Read More

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http://dx.doi.org/10.23736/S0392-9590.19.04158-0DOI Listing
April 2019
1 Read

Open distal anastomosis in the frozen elephant trunk technique: initial experiences and preliminary results of arch zone 2 versus arch zone 3†.

Eur J Cardiothorac Surg 2019 Apr 1. Epub 2019 Apr 1.

Cardiac Surgery Unit, Cardio-Thoracic-Vascular Department, S. Orsola Hospital, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Objectives: We compared the results of 2 groups of patients who underwent aortic arch replacement with the frozen elephant trunk technique. In the first group, the distal anastomosis was performed in arch zone 2; in the second control group, the distal anastomosis was performed in arch zone 3.

Methods: Between January 2007 and April 2018, the frozen elephant trunk technique was used in 282 patients. Read More

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http://dx.doi.org/10.1093/ejcts/ezz103DOI Listing
April 2019
1 Read

A Case of Thoracic Endovascular Aortic Repair Using Carotid Access with Axillary-Carotid Bypass for Descending Aortic Aneurysm in a Patient with Aortoiliac Occlusive Disease.

Ann Vasc Dis 2019 Mar;12(1):105-108

Department of Cardiovascular Surgery, Chiba Cerebral and Cardiovascular Center, Ichihara, Chiba, Japan.

The authors report a 71-year-old male with descending thoracic aortic aneurysm and multiple risk factors (aortoiliac occlusive disease, obesity, ascending aorta dilatation, and history of left ventriculoperitoneal shunt for hydrocephalus) who was treated with thoracic endovascular aortic repair (TEVAR) via left common carotid artery (LCCA) access and left axillary-carotid artery (Ax-CA) bypass; this approach shortened the LCCA clamp time during the procedure. The patient was discharged without any complications. TEVAR via LCCA access with left Ax-CA bypass is a useful and safe procedure for patients in whom conventional femoral artery access is not feasible. Read More

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http://dx.doi.org/10.3400/avd.cr.18-00143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434357PMC
March 2019
1 Read

Endovascular Treatment for a Perforated Superficial Femoral Vein Graft for an Infected Abdominal Aortic Aneurysm.

Ann Vasc Dis 2019 Mar;12(1):91-94

Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

The patient had an infected abdominal aortic aneurysm. Aneurysmectomy and in situ reconstruction of the abdominal aorta using the bilateral superficial femoral veins with omentopexy were performed. On postoperative day 18, hematemesis and melena occurred. Read More

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http://dx.doi.org/10.3400/avd.cr.18-00095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434355PMC
March 2019
2 Reads

Hybrid Therapy for Mycotic Aortic Aneurysm with Stent-Graft and Video-Assisted Thoracoscopic Debridement.

Ann Vasc Dis 2019 Mar;12(1):69-73

Department of Thoracic and Cardiovascular Surgery, Ise Red Cross Hospital, Ise, Mie, Japan.

Treating mycotic aortic aneurysm with thoracic endovascular aortic repair (TEVAR) remains controversial because of sustained infection post-treatment. In this study, an 83-year-old man, who had a ruptured mycotic thoracic aortic aneurysm, underwent salvage TEVAR. However, because an abscess appeared in the aneurysm on follow-up computed tomography, video-assisted thoracoscopic debridement (VATD) followed by continuous drainage was performed next and was successful in eliminating the infection from the abscess. Read More

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http://dx.doi.org/10.3400/avd.cr.18-00119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434360PMC
March 2019
2 Reads

[Distal Stentgraft-induced New Entry Developed after Surgery for Aortic Dissection].

Kyobu Geka 2019 Mar;72(3):173-177

Department of Endovascular Surgery, Tokushima Red Cross Hospital, Komatsushima,Japan.

We experienced 2 cases with distal stentgraft-induced new entry (distal SINE) after thoracic endovascular aortic repair( TEVAR) for type B aortic dissection and 1 case after total arch replacement and frozen elephant trunk method for type A dissection. We successfully performed additional TEVAR in all cases. If the stent graft is bent at deployment, distal SINE may occur on the great curvature side of the aorta by the spring back force. Read More

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March 2019
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Surgical Repair of an Arch and Descending Aortic Aneurysm in a Child.

Ann Thorac Surg 2019 Mar 25. Epub 2019 Mar 25.

Department of Cardiovascular Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

Pediatric thoracic aortic aneurysms are very rare, and almost all patients with such aneurysms have inflammatory or connective tissue diseases. We describe a case involving 10-year-old girl who had an arch and descending thoracic aortic aneurysm. Preoperative F-fluorodeoxyglucose positron emission tomography-computed tomography showed an inflammatory lesion corresponding to the aneurysm's location. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.02.048DOI Listing
March 2019
1 Read

Double homemade fenestrated stent graft for total endovascular aortic arch repair.

J Vasc Surg 2019 Mar 25. Epub 2019 Mar 25.

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

Objective: The aim of this retrospective analysis was to evaluate the outcomes of physician-modified double fenestrated stent grafts for total endovascular aortic arch repair: one proximal large fenestration for the brachiocephalic trunk and the left common carotid artery and one distal fenestration for the left subclavian artery (LSA).

Methods: From January 2017 through February 2018, 17 patients (88.2% elective) underwent thoracic endovascular aortic repair (TEVAR) with double homemade fenestrated stent graft for total endovascular aortic arch repair to maintain supra-aortic trunk patency. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.11.054DOI Listing
March 2019
2 Reads

The interaction effects between TLR4 and MMP9 gene polymorphisms contribute to aortic aneurysm risk in a Chinese Han population.

BMC Cardiovasc Disord 2019 Mar 29;19(1):72. Epub 2019 Mar 29.

Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, No.155 Nanjing Bei Street, Heping District, Shenyang, Liaoning Province, People's Republic of China, 110001.

Background: A cross-talk between Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) plays a vital role in aortic pathophysiology. The objective of this study was to evaluate the interactions between TLR4 and MMP9 polymorphisms in the risk of aortic aneurysm (AA) and its subtypes.

Methods: KASP method was used to detect polymorphisms of TLR4 (rs11536889 and rs1927914) and MMP9 (rs17576) in 472 AA patients and 498 controls. Read More

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http://dx.doi.org/10.1186/s12872-019-1049-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439981PMC
March 2019
1 Read

Baseline findings of the population-based, randomized, multifaceted Danish cardiovascular screening trial (DANCAVAS) of men aged 65-74 years.

Br J Surg 2019 Mar 27. Epub 2019 Mar 27.

Elitary Research Centre of Individualized Medicine in Arterial Disease (CIMA), Department of Cardiology, Odense University Hospital, Odense, Denmark.

Background: The challenge of managing age-related diseases is increasing; routine checks by the general practitioner do not reduce cardiovascular mortality. The aim here was to reduce cardiovascular mortality by advanced population-based cardiovascular screening. The present article reports the organization of the study, the acceptability of the screening offer, and the relevance of multifaceted screening for prevention and management of cardiovascular disease. Read More

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http://dx.doi.org/10.1002/bjs.11135DOI Listing
March 2019
5 Reads

[Aortic aneurism dissection in an adult patient with tuberculosis infected with HIV-1 during immune reconstitution inflammatory syndrome].

Pan Afr Med J 2018 4;31:10. Epub 2018 Sep 4.

Programme PAC-CI, site ANRS de Côte d'Ivoire, CHU de Treichville, Abidjan, Côte d'Ivoire.

We here report the case of a 35-year old man with HIV-1 but with no previous medical-surgical history hospitalized in Abidjan, Côte d'Ivoire, due to fever, cough, dyspnea, chest pain and unfolding of the aortic arch observed on chest x-ray a week after having started antiretroviral therapy (ART). CT angiography of the thoracic aorta showed overall, extended aortic ectasia with mural thrombus. Transesophageal echocardiography objectified type A ascending aortic dissection (Stanford classification). Read More

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http://dx.doi.org/10.11604/pamj.2018.31.10.12824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430942PMC
April 2019
1 Read

Management of abdominal aortic aneurysm and concomitant malignant disease.

J Cardiovasc Surg (Torino) 2019 Mar 22. Epub 2019 Mar 22.

Department of Thoracic and Vascular Surgery, Ghent University Hospital, Ghent, Belgium -

Background: Concomitant malignant disease and abdominal aortic aneurysms (AAA) represent a challenging issue in terms of treatment priority, timing and perspectives. This narrative review provides an overview of the available literature managing AAA and concomitant malignant disease.

Methods: We conducted a literature search of all the English-language medical literature in Medline (through PubMed), Embase, Clinical Trial databases and the Cochrane Library up to December 31st, 2018. Read More

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http://dx.doi.org/10.23736/S0021-9509.19.10946-9DOI Listing
March 2019
1 Read

Left Ventricular Assist Device Implantation Combined with Bentall Procedure.

Braz J Cardiovasc Surg 2019 Mar-Apr;34(2):233-236

Departments of Anesthesiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.

Ventricular assist devices (VADs) are an important technological development for patients with end-stage heart failure, and approximately 50% of these patients require various additional cardiac procedures. Here we presente the case of a patient suffering from severe aortic insufficiency, aortic root dilatation, and an ascending aortic aneurysm with end-stage decompensated heart failure. We performed the Bentall procedure combined with a left VAD implantation during the same session. Read More

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http://dx.doi.org/10.21470/1678-9741-2018-0123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436771PMC
April 2018
1 Read

Outcome After Endovascular Repair of Ruptured Descending Thoracic Aortic Aneurysm: A National Multicentre Study.

Eur J Vasc Endovasc Surg 2019 Mar 22. Epub 2019 Mar 22.

Department of Vascular Surgery, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. Electronic address:

Objective: The purpose of this multicentre study was to analyse the outcome of thoracic endovascular aortic repair (TEVAR) in patients with ruptured descending thoracic aortic aneurysm (rDTAA).

Methods: This is a nationwide retrospective study including all patients who underwent TEVAR for rDTAA at six major vascular university centres in Sweden between January 2000 and December 2015. Outcome measures were analysed using Kaplan-Meier estimator and multivariable Cox regression. Read More

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http://dx.doi.org/10.1016/j.ejvs.2018.10.029DOI Listing
March 2019
1 Read

Impact of Polar Renal Artery Coverage on Early Renal Function after Chimney Endovascular Aortic Aneurysm Repair.

J Vasc Interv Radiol 2019 Apr;30(4):539-545

Centre Méditerranéen de Médecine Moléculaire (C3M), Université Côte d'Azur, CHU, Inserm, Nice, France.

Purpose: To evaluate impact of polar renal artery coverage on early renal function after chimney endovascular aneurysm repair (EVAR).

Materials And Methods: Consecutive patients who underwent chimney EVAR for treatment of asymptomatic juxtarenal abdominal aortic aneurysm were retrospectively included. Estimated glomerular filtration rate (eGFR) was recorded before the intervention and at 1-, 5-, 7-, and 30-day follow-up. Read More

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http://dx.doi.org/10.1016/j.jvir.2018.11.031DOI Listing
April 2019
1 Read

Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions.

J Vis Exp 2019 Mar 8(145). Epub 2019 Mar 8.

Saha Cardiovascular Research Center, University of Kentucky; Department of Physiology, University of Kentucky;

Contemporary high-resolution ultrasound instruments have sufficient resolution to facilitate the measurement of mouse aortas. These instruments have been widely used to measure aortic dimensions in mouse models of aortic aneurysms. Aortic aneurysms are defined as permanent dilations of the aorta, which occur most frequently in the ascending and abdominal regions. Read More

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http://dx.doi.org/10.3791/59013DOI Listing
March 2019
1 Read

Rapamycin attenuates a murine model of thoracic aortic aneurysm by downregulating the miR-126-3p mediated activation of MAPK/ERK signalling pathway.

Biochem Biophys Res Commun 2019 May 21;512(3):498-504. Epub 2019 Mar 21.

Department of Vascular Surgery, Peking University People's Hospital, Beijing, 100044, China. Electronic address:

Thoracic aortic aneurysm (TAA) is fatal diseases, which leads to aortic rupture and sudden death. Blood pressure-lowering drugs are ineffective for most of the patients. Our previous study demonstrated the inhibition of endothelial secreted miR-126-3p by rapamycin ameliorate the aneurysmal phenotype of smooth muscle cells (SMCs) in vitro. Read More

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http://dx.doi.org/10.1016/j.bbrc.2019.03.083DOI Listing
May 2019
3 Reads
2.297 Impact Factor

Fate of preserved bicuspid valves at time of ascending aortic aneurysmectomy.

J Card Surg 2019 Mar 21. Epub 2019 Mar 21.

Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut.

Background: The fate of the spared bicuspid aortic valve in patients undergoing ascending aortic aneurysm surgery is relatively unknown. Our institutional policy has been to replace all aortic valves with significant abnormalities, as evidenced by intraoperative transesophageal echocardiography or direct visual inspection. In this study, we elaborate our experience regarding the long-term fate of preserved bicuspid aortic valves after ascending aortic aneurysm extirpation. Read More

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http://dx.doi.org/10.1111/jocs.14024DOI Listing
March 2019
1 Read

Physician-Modified Thoracic Stent-Grafts for the arch after surgical treatment of type A dissection.

Ann Thorac Surg 2019 Mar 18. Epub 2019 Mar 18.

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

Background: This study evaluates the outcome of physician modified thoracic stent-grafts for the treatment of dissecting aortic arch aneurysms after surgical treatment of acute type A dissection.

Methods: From August 2016 through February 2018, 13 patients underwent TEVAR using physician modified thoracic stent-grafts to treat dissecting aortic arch aneurysms after surgical treatment of acute type A dissection. There were 8 men and 5 women (mean age, 70. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.02.026DOI Listing
March 2019
4 Reads

Impact of preservation of the latissimus dorsi muscle through a left anteroaxillary thoracotomy on spinal cord protection in descending thoracic and thoraco-abdominal aortic operations†.

Eur J Cardiothorac Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.

Objectives: The presence of collateral network circulation to the spinal cord, which is reflected in the repair of a descending thoracic aortic aneurysm (dAo) and a thoraco-abdominal aortic aneurysm (TAAo), has been demonstrated in clinical and animal experimental data. The latissimus dorsi muscle (LDM) including the thoracodorsal artery might be one of the major sources of this collateral network. The objective of this study was to evaluate the impact on spinal cord safety of a left anteroaxillary thoracotomy with minimal muscle division including preservation of the LDM in surgery for dAo and TAAo. Read More

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http://dx.doi.org/10.1093/ejcts/ezz087DOI Listing
March 2019
2 Reads

Ruptured Syphilitic Aneurysm: A Cause of Sudden Death in a Man with Human Immunodeficiency Coinfection.

J Forensic Sci 2019 Mar 20. Epub 2019 Mar 20.

Department of Legal Medicine, St. Marianna University School of Medicine, Kanagawa, 216-8511, Japan.

Syphilis, a sexually transmitted infection caused by the bacterium Treponema palladium, is experiencing a worldwide resurgence. The risk of syphilis infection is particularly high in men who have sex with men (MSM), especially those who are human immunodeficiency virus (HIV)-positive. Untreated syphilis can lead to rare but severe late-stage complications, including syphilitic aortitis. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1556-4029.14
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http://dx.doi.org/10.1111/1556-4029.14046DOI Listing
March 2019
3 Reads

Exercise and sports participation in patients with thoracic aortic disease: a review.

Expert Rev Cardiovasc Ther 2019 Apr 21;17(4):251-266. Epub 2019 Mar 21.

a Department of Cardiology , Erasmus MC, University Medical Center Rotterdam , Rotterdam , The Netherlands.

Introduction: Current guidelines recommend patients with thoracic aortic disease (TAD) including inherited aortopathies to avoid heavy exercise. However, evidence supporting the negative advice on exercise is scarce. We aimed to provide an up-to-date systematic review of the available evidence on risks and benefits of exercise and sports participation in TAD patients. Read More

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http://dx.doi.org/10.1080/14779072.2019.1585807DOI Listing
April 2019
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Successful Resuscitation Using Extracorporeal Membrane Oxygenation of 2 Patients With Severe Liver Rupture: A Case Report.

A A Pract 2019 Mar 14. Epub 2019 Mar 14.

Anesthesiology and Critical Care Medicine.

Extracorporeal membrane oxygenation is a rescue treatment for respiratory or cardiac failure. Its use is limited in patients predisposed to bleeding due to heparin administration. We present 2 patients with deranged coagulation after liver rupture successfully treated by extracorporeal membrane oxygenation. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000996DOI Listing
March 2019
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A new inclusion technique through an upper partial sternotomy for complicated Stanford B-type aortic dissection with an aberrant right subclavian artery: A case report.

Medicine (Baltimore) 2019 Mar;98(11):e14727

Department of Cardiovascular Surgery, Second Hospital of Jilin University, Changchun, Jilin, China.

Rationale: An aberrant right subclavian artery (ARSA), arising from the proximal descending aorta, is a common aortic arch anomaly, with an incidence of 0.5% to 2%. However, coexistence of dissection and an ARSA is extremely rare. Read More

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http://dx.doi.org/10.1097/MD.0000000000014727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426566PMC
March 2019
2 Reads

Endovascular Treatment of Aorta-Iliac Aneurysms with a Flared Iliac Limb.

Int J Angiol 2019 Mar 2;28(1):57-63. Epub 2019 Mar 2.

Department of Thoracic, Vascular and Cardiac Surgery, Odense University Hospital, Odense C, Denmark.

Endovascular abdominal aneurysm repair (EVAR) relies on the quality of the proximal and distal landing zone. Reinterventions are higher in patients with suboptimal landing zone. The study aimed to evaluate reintervention rate after endovascular treatment of an aorta-iliac aneurysm using the flared iliac limbs. Read More

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http://dx.doi.org/10.1055/s-0039-1683411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417901PMC
March 2019
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Symptoms Matter: A Symptomatic but Radiographically Elusive Ascending Aortic Dissection.

Int J Angiol 2019 Mar 29;28(1):31-33. Epub 2018 Nov 29.

Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut.

Symptoms attributable to a thoracic aortic aneurysm (TAA) are a separate indication for prophylactic repair, irrespective of aortic size. We present the case of a 56-year-old female with a history of a thoracic ascending aortic aneurysm (TAAA) and four other heart and arch vessel abnormalities who presented to us with chest pain radiating to her back. Computed Tomography and echocardiography showed no evidence of a dissection and revealed a maximal ascending aortic diameter of 4. Read More

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http://dx.doi.org/10.1055/s-0038-1675849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417893PMC
March 2019
2 Reads

Long-term survival and frequency of reinterventions after proximal aortic surgery: a retrospective study†.

Eur J Cardiothorac Surg 2019 Mar 15. Epub 2019 Mar 15.

Department of Thoracic Surgery, Institution of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden.

Objectives: We sought to analyse perioperative outcome, long-term mortality, frequency and causes of reintervention, and survival benefit in a contemporary cohort of patients undergoing proximal thoracic aortic surgery.

Methods: Participants comprised all patients undergoing open surgery for proximal thoracic aortic aneurysm (TAA) (n = 319) and thoracic aortic dissection type A (TAD) (n = 229) during 2005-2014 at the Department of Thoracic Surgery, Uppsala University Hospital. Long-term survival was compared to age- and sex-matched controls. Read More

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http://dx.doi.org/10.1093/ejcts/ezz073DOI Listing
March 2019
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Improvement in the Assessment of Aortic Valve and Aortic Aneurysm Repair by 3-Dimensional Echocardiography.

JACC Cardiovasc Imaging 2019 Mar 8. Epub 2019 Mar 8.

Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/Saar, Germany.

Reconstructive surgery of the aortic valve is being increasingly used in patients with aortic regurgitation and/or aortic aneurysm. Its success depends on restoring normal aortic valve and root form. Echocardiography is the most reliable and precise imaging technique because it defines abnormal morphology and function, essential for selecting appropriate substrates and guiding the surgical strategy. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.06.032DOI Listing
March 2019
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The Coagulopathy of Acute Type A Aortic Dissection: A Prospective, Observational Study.

J Cardiothorac Vasc Anesth 2019 Feb 11. Epub 2019 Feb 11.

Lund University, Skåne University Hospital, Department of Clinical Sciences, Lund, Department of Cardiothoracic Surgery, Lund, Sweden.

Objective: To evaluate the hemostatic system in patients undergoing surgery for acute type A aortic dissection (ATAAD) compared with those undergoing elective aortic procedures.

Design: This was a prospective, observational study.

Setting: The study was performed at a single university hospital. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10530770193014
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http://dx.doi.org/10.1053/j.jvca.2019.02.013DOI Listing
February 2019
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Thrombectomy and reconstruction of the left vertebral artery after total arch replacement: never give up on postoperative stroke.

Gen Thorac Cardiovasc Surg 2019 Mar 14. Epub 2019 Mar 14.

Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.

The patient was a 64-year-old man who had aortic regurgitation, ischemic heart disease, a transverse aortic aneurysm, and an abdominal-common iliac aneurysm. Concomitant operations including aortic valve replacement, coronary artery bypass grafting, and total aortic arch replacement with elephant trunk technique were performed successfully. The patient developed postoperative cardiac tamponade on the 5th postoperative day, resulting in bulbar palsy due to occlusion of the dominant left vertebral artery. Read More

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http://dx.doi.org/10.1007/s11748-019-01106-6DOI Listing
March 2019
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Pseudoaneurysm of the Thoracoabdominal Aortic Graft due to Intercostal Nerve Block.

Ann Thorac Surg 2019 Mar 11. Epub 2019 Mar 11.

Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA. Electronic address:

Pseudoaneurysms of the descending aorta after open graft replacement usually occur in patients with connective tissue disorders and form at anastomotic or cannulation sites. We present a case of an iatrogenic pseudoaneurysm in the descending thoracic aortic graft body caused by intercostal nerve block. The patient had undergone repair for thoracoabdominal aortic aneurysm four years prior and underwent a series of intercostal nerve blocks after experiencing persistent post-thoracotomy pain. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.01.073DOI Listing
March 2019
1 Read