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J Perioper Pract 2020 Jul 10:1750458920936064. Epub 2020 Jul 10.

Icahn School of Medicine at Mount Sinai, New York, USA.

Thoracic aortic aneurysms present significant challenges to clinicians, especially due to their complex nature and an evolving understanding of the safest and most effective ways to manage this condition in the perioperative setting. Thoracic aortic aneurysms have a prevalence rate of 1.3-8. Read More

J Am Coll Cardiol 2020 Jul;76(2):201-217

Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Connecticut; Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, Connecticut.

Clinicians often encounter discrepant measurements of the ascending aorta that impede, complicate, and impair appropriate clinical assessment-including key issues of presence or absence of aortic growth, rate of growth, and need for surgical intervention. These discrepancies may arise within a single modality (computed tomography scan, magnetic resonance imaging, or echocardiography) or between modalities. The authors explore the origins and significance of these discrepancies, revealing that some "truth" usually underlies all the discrepant measurements, which individually look at the ascending aorta with different perspectives and dimensional definitions. Read More

Eur J Prev Cardiol 2020 Jul 9:2047487320936782. Epub 2020 Jul 9.

Department of Cardiology, Clinic Barmelweid, Switzerland.

Ann Vasc Surg 2020 Jul 6. Epub 2020 Jul 6.

Department of Surgery, Boston Medical Center, Boston University, School of Medicine, Boston, MA. Electronic address:

Background: The present study compares the senior level operative experience of graduates from the traditional vascular surgery fellowship (5+2) and integrated vascular surgery training programs (0+5) using contemporary operative case log data.

Methods: The Accreditation Council for Graduate Medical Education (ACGME) integrated vascular surgery, vascular surgery fellowship, and general surgery case logs for trainees graduating between 2013 and 2018 were queried for vascular surgery procedures. 'Senior' cases were categorized as cases logged as 'Surgeon Fellow' by 5 + 2 trainees or 'Surgeon Chief' (PGY-4,5) by 0 + 5 trainees. Read More

Pediatr Cardiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute, 28, Hohyeon-ro 489 Beon-gil, Sosa-gu, Bucheon, Gyeonggi-do, 422-711, Republic of Korea.

Aortic root dilatation is frequently encountered in adults with repaired Tetralogy of Fallot (TOF). The timing of total repair is known to have a significant correlation with late aortic root dilatation, but it is not well established. The objective of this study was to investigate the risk factors and correlation with timing of total repair for aortic root dilatation in adults with repaired TOF. Read More

Neurol Clin Pract 2020 Jun;10(3):245-254

Department of Neurology (SMT, JEA, JRD, KAJ), Mayo Clinic, Rochester, MN; and Department of Neurology (JYM), University of Minnesota, Minneapolis, MN.

Background: A rare progressive supranuclear palsy-like syndrome seemingly triggered by aortic surgery was first described in 2004. This largest case series to date describes the features of this syndrome.

Methods: We searched the Mayo Clinic electronic medical records using the advanced cohort explorer search engine for patients evaluated for neurologic symptoms after cardiac-aortic surgery in the past 30 years. Read More

J Thorac Dis 2020 May;12(5):2474-2481

Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

Background: Total arch replacement (TAR) with frozen elephant trunk (FET) was challenging in patients with prior thoracic endovascular aortic repair (TEVAR), for complicated arch pathology and anatomy. In this study, we aimed to present our experiences in TAR with FET after prior TEVAR, and compare the clinical outcomes between the aortic balloon occlusion technique and the conventional technique.

Methods: Between January 2016 and December 2019, 30 patients with prior TEVAR received TAR with FET in our hospital. Read More

J Thorac Dis 2020 May;12(5):2304-2316

Anatomic Pathology, Department of Biomedicine and Prevention Tor Vergata University, Rome, Italy.

Background: We sought to investigate and compare biomechanical properties and histomorphometric findings of thoracic ascending aorta aneurysm (TAA) tissue from patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) in order to clarify mechanisms underlying differences in the clinical course.

Methods: Circumferential sections of TAA tissue in patients with BAV (BAV-TAA) and TAV (TAV-TAA) were obtained during surgery and used for biomechanical tests and histomorphometrical analysis.

Results: In BAV-TAA, we observed biomechanical higher peak stress and lower Young modulus values compared with TAV-TAA wall. Read More

J Thorac Dis 2020 May;12(5):2270-2279

Key Laboratory of Cardiovascular Disease of Yunnan Province, Kunming 650051, China.

Background: The aim of this retrospective study was to evaluate the feasibility and efficacy of thoracic endovascular aortic repairs (TEVAR) combined with looping chimney technique (LCT) for repairing aortic arch lesions and reconstructing left common carotid artery.

Methods: Total of 14 patients (mean age 52.86±14. Read More

J Vasc Surg 2020 Jul 5. Epub 2020 Jul 5.

Division of Vascular and Endovascular Surgery, Weill Cornell Medicine, New York-Presbyterian Hospital, New York. Electronic address:

Objective: Spinal cord injury (SCI) is one of the most devastating complications of thoracoabdominal aortic aneurysm (TAAA) repair. Cerebrospinal fluid drainage (CSFD) is routinely used to prevent and treat SCI during open TAAA repair. However, the risks and benefits of CSFD during fenestrated-branched endovascular aneurysm repair (F-BEVAR) are unclear. Read More

Prog Cardiovasc Dis 2020 Jul 5. Epub 2020 Jul 5.

University Clinic of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany. Electronic address:

Patients with a bicuspid aortic valve (BAV) frequently develop aneurysms of the aortic root and tubular ascending aorta. Aneurysms of the aortic arch, in the absence of concomitant aortopathies, are much less common. According to the 2018 American Association of Thoracic Surgery consensus guidelines on BAV-related aortopathy, prophylactic surgical aortic repair / replacement is recommended starting at a maximum aortic diameter of 50 mm in patients with risk factors. Read More

J Biomech 2020 Jul 14;108:109884. Epub 2020 Jun 14.

Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA, United States; Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, United States; Surgery, University of Pittsburgh, Pittsburgh, PA, United States; Center for Vascular Remodeling and Regeneration, University of Pittsburgh, Pittsburgh, PA, United States; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Clinical and Translational Sciences Institute, University of Pittsburgh, Pittsburgh, PA, United States.

Type A Aortic Dissection (TAAD) is a life-threatening condition involving delamination of ascending aortic media layers. While current clinical guidelines recommend surgical intervention for aneurysm diameter > 5.5 cm, high incidence of TAAD in patients below this diameter threshold indicates the pressing need for improved evidence-based risk prediction metrics. Read More

Ann Vasc Surg 2020 Jul 4. Epub 2020 Jul 4.

Department of Cardiovascular Surgery, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address:

Objective: Aortic stent grafting can cause aortic stiffening and increase pulse wave velocity (PWV), which can potentially affect long-term cardiovascular outcomes. The aim of this study was to clarify the factors contributing to increases in PWV after thoracic endovascular aortic repair (TEVAR).

Methods: We included 64 patients with thoracic aortic pathology (51 men; mean age: 73 years) who underwent elective TEVAR, in this study. Read More

Vasc Endovascular Surg 2020 Jul 7:1538574420937557. Epub 2020 Jul 7.

Division of Vascular Surgery, Department of Surgery, Mayo Clinic Florida, Jacksonville, FL, USA.

Contained rupture of an aortic aneurysm is a high-mortality condition that requires immediate repair. Open repair has been the gold standard; however, endovascular and hybrid open-endovascular repair techniques have also emerged as less invasive solutions to this vascular emergency. Here. Read More

Eur Rev Med Pharmacol Sci 2020 Jun;24(12):6949-6954

Department of Vascular Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.

Objective: The purpose of this study was to explore the changes in the expressions of micro ribonucleic acid (miR)-22-3p and matrix metalloproteinase-9 (MMP-9) in rats with thoracic aortic aneurysm (TAA) and their significance.

Materials And Methods: A total of 16 specific pathogen-free Sprague-Dawley female rats were randomly divided into normal group (n=8) and angiotensin II (Ang II) group (n=8). Ang II was perfused using the micro pump in Ang II group, while the same amount of normal saline was perfused in the normal group. Read More

J Vasc Surg 2020 Jul 3. Epub 2020 Jul 3.

University of Pennsylvania, Philadelphia, PA.

Thoracic aortic diseases, including disease of the descending thoracic aorta (DTA), are significant causes of death in the United States. Open repair of DTA is a physiologically impactful operation with relatively high rates of mortality, paraplegia, and renal failure. Thoracic endovascular aneurysm repair (TEVAR) has revolutionized the treatment of DTA, and has largely supplanted open repair due to lower morbidity and mortality. Read More

J Thorac Cardiovasc Surg 2020 May 27. Epub 2020 May 27.

Istituto Auxologico Italiano, IRCCS, Cardiology Unit, Milan, Italy; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.

Objectives: To evaluate aortic distensibility and pulse waveform patterns associated with the ascending aortic aneurysm, and to analyze the postoperative and mid-term hemodynamic changes induced by prosthetic replacement of the ascending aorta.

Methods: Central blood pressure waves were recorded at the carotid artery level by means of a validated transcutaneous arterial tonometer in 30 patients undergoing prosthetic replacement of ascending aortic aneurysm and in 30 control patients. Measurements were obtained the day before surgery and 5 to 7 days and 16 to 20 months after surgery. Read More

Eur J Cardiothorac Surg 2020 Jul 5. Epub 2020 Jul 5.

Department of Cardiovascular Surgery, Tokyo Women's Medical University, The Heart Institute of Japan, Shinjukuku, Tokyo, Japan.

Objectives: Thoracic endovascular aortic repair (TEVAR) for the treatment of aortic arch disease remains challenging due to certain anatomical and haemodynamic features. The purpose of this study was to evaluate the midterm results of TEVAR with a second-generation fenestrated endograft for aortic arch disease.

Methods: This non-randomized, interventional study was part of a multicentre clinical trial conducted between 2010 and 2011 and was designed to assess the effectiveness of a second-generation precurved fenestrated endograft for aortic arch disease. Read More

J Vasc Surg 2020 Jul 1. Epub 2020 Jul 1.

Comprehensive Aortic Center, Keck Medical Center of University of Southern California, Los Angeles, CA.

Objective: Revascularization of the left subclavian artery (LSA) during zone 2 thoracic endovascular aortic repair (TEVAR) maintains collateral circulation to decrease ischemic complications including stroke, spinal cord ischemia, and upper extremity ischemia. Both open surgical and endovascular LSA revascularization techniques have been described, each with unique risks and benefits. We describe our "periscope sandwich" technique for the LSA during zone 2 TEVAR, which maintains antegrade access to the distal abdominal aorta if subsequent interventions are necessary. Read More

Clin Radiol 2020 Jun 29. Epub 2020 Jun 29.

Vascular Interventional Radiology, Leeds Teaching Hospital NHS Trust, Leeds, UK.

Aim: To present the authors' experience of endovascular treatment of confirmed and presumed (microbiology negative) mycotic aortic aneurysms (MAA).

Materials And Methods: Patients undergoing endovascular aortic repair were identified retrospectively from 1998 using the radiology information system and an internally kept database until 2018. The primary aim was to assess the technical success and peri-operative morbidity and mortality. Read More

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 Jun;42(3):319-326

Department of Cardiovascular Surgery,National Center for Cardiovascular Disease,Fuwai Hospital, CAMS and PUMC,Beijing 100037,China.

To evaluate the early and mid-term results after surgical repair of thoracoabdominal aortic aneurysm(TAAA)in patients with DeBakey typeⅠor Ⅲ aortic dissection. The clinical data of 130 patients who underwent TAAA repair for chronic DeBakey typeⅠ(groupⅠ, =47)or type Ⅲ(group Ⅲ, =83)aortic dissections in our center between January 2009 and December 2017 were retrospectively analyzed.Early postoperative results,midterm survival,and re-interventions were compared between these two groups. Read More

Phys Med 2020 Jun 29;76:77-84. Epub 2020 Jun 29.

Department of Thoracic and Vascular Surgery, Ghent University Hospital, Ghent, Belgium. Electronic address:

Purpose: In laparoscopy, the Operating Room Black Box® (ORBB) provides insights into operative performance to improve patient safety. This technology may also enhance endovascular surgical practice; however, the use of a C-arm and X-rays pose important challenges, hindering transferability to an endovascular context. We describe the first implementation of ORBB technology in a hybrid angiosuite and illustrate its value in evaluating surgeons' radiation safety, technical and non-technical performance. Read More

Ann Thorac Cardiovasc Surg 2020 Jul 2. Epub 2020 Jul 2.

Department of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.

Purpose: This study was conducted to identify predictors of respiratory failure after open repair of descending thoracic aortic aneurysm (DTAA), and to identify any relationship between respiratory failure and long-term survival.

Methods: A total of 75 patients undergoing elective open DTAA repair at the Shiga University of Medical Science Hospital were included in the study. Univariate and multivariate logistic regression analyses were performed to assess the odds ratios for incident postoperative respiratory failure after open DTAA repair. Read More

Magy Seb 2020 Jun;73(2):61-68

Szív-, Ér-, és Mellkassebészeti Osztály,HM Egészségügyi Központ Budapest.

Incidence of anomalies of the aortic arch is estimated 1-2 per cent in newborn babies. Lusory artery may arise either from left sided aortic arch in 0.7-2 per cent, or from right sided aortic arch in 0. Read More

J Cardiopulm Rehabil Prev 2020 Jul;40(4):215-223

Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, Michigan (Drs Ehrman and Keteyian); The Heart and Vascular Institute, Hartford Hospital, Hartford, Connecticut (Drs Fernandez and Thompson); VA Medical Center, Palo Alto, California (Dr Myers); and University Health Network, Toronto, Ontario, Canada (Dr Oh).

Background: Some patients who participate in cardiac rehabilitation have aortic abnormalities, including abdominal and thoracic aneurysm (AAA and TAA, respectively). There is scant guidance on implementing exercise training in these individuals. This article reviews the epidemiology, diagnostic process, medical issues, and the available exercise training literature, and provides recommendations for performing regular exercise. Read More

Ann Vasc Surg 2020 Jun 27. Epub 2020 Jun 27.

Division of Vascular Surgery, Stanford University, Stanford, CA.

Objectives: Thoracic endovascular aneurysm repair (TEVAR) has become the current standard of care for emergent treatment of blunt traumatic aortic injuries (BTAI). Although aortic dilation of the infrarenal neck following EVAR for aortic aneurysms has been studied, changes in aortic diameter following TEVAR for BTAI is not well understood. This study aims to characterize changes in thoracic aortic diameter following stent graft placement in the setting of non-aneurysmal traumatic aortic injury. Read More

Tex Heart Inst J 2020 Apr;47(2):149-151

Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine; and Department of Cardiovascular Surgery, Texas Heart Institute; Houston, Texas 77030.

Successful surgical repair of aortic coarctation during childhood may have major late complications such as pseudoaneurysm formation. If left untreated, pseudoaneuryms put patients at risk for morbidity and death; if treated surgically, they are associated with complications. Endovascular aortic repair, an established safe alternative to open surgical repair, is associated with encouraging outcomes and fewer complications, and it is especially feasible for patients who have undergone multiple aortic surgeries. Read More

Aorta (Stamford) 2020 Feb 29;8(1):6-13. Epub 2020 Jun 29.

Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Background:  Cardiac events following thoracic endovascular aortic repair (TEVAR) have been associated with significant morbidity and mortality. However, predictors of post-TEVAR cardiac events in descending thoracic aortic aneurysm or dissection are poorly understood.

Methods:  A retrospective analysis of completed TEVAR procedures performed from 2010 to 2016 was conducted using the ACS-NSQIP (American College of Surgeons National Surgical Quality Improvement Program) participant user file database. Read More

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Division of Vascular Diseases and Surgery, Department of Surgery, Ohio State University Wexner Medical Center, 376 West 10(th) Avenue, Columbus, OH. Electronic address:

Objectives: Human immunodeficiency virus (HIV) is a multisystem disease and associated with vascular complications including aneurysm formation. HIV-associated aneurysms are well-documented and may present in unusual locations with concerning features. However, the majority of the literature regarding aneurysms in HIV-positive patients are limited to case series with limited data regarding aneurysm patterns. Read More

Angiol Sosud Khir 2020 ;26(2):175-182

Department of Vascular Surgery, Municipal Multimodality Hospital #2, Saint Petersburg, Russia.

Described herein is a clinical case report regarding a patient presenting with traumatic rupture of the aortic isthmus with the development of a pseudoaneurysm occupying virtually the entire posterior mediastinum and measuring 20?10 cm in size. He was immediately treated as an emergency to undergo prosthetic reconstruction of the portion of the aortic arch and descending thoracic aorta by means of temporary bypass grafting with a synthetic graft in order to protect the visceral organs. The postoperative period was complicated by oesophageal perforation with the formation of an oesophago-paraprosthetic fistula, infection of the vascular graft, accompanied by the development of pleural empyema and mediastinitis. Read More

Angiol Sosud Khir 2020 ;26(2):163-169

Cardiovascular Surgery Department, Emergency Hospital, Naberezhnye Chelny, Russia.

Presented herein is a clinical case report regarding hybrid techniques successfully used in a patient suffering from a Crawford type III thoracoabdominal aortic aneurysm and DeBakey type IIIB aortic dissection. The first stage consisted in endoprosthetic reconstruction of the descending portion of the thoracic aorta, with the second stage including visceral debranching with endoprosthetic reconstruction of the thoracoabdominal portion of the aorta. As the final stage, the patient was subjected to debranching of brachiocephalic arteries, followed by endoprosthetic repair of the aortic arch. Read More

Mol Genet Genomic Med 2020 Jun 29:e1378. Epub 2020 Jun 29.

Department of Cardiovascular Genetics and The Laboratory of Forensic Genetics, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

Background: Thoracic aortic aneurysm and dissection (TAA/D) represents a potentially lethal disease group characterized by an increased risk of dissection or rupture. Only a small percentage (approximately 30%) of individuals with nonsyndromic familial TAA/D have a pathogenic variant in one of the genes that have been found to be associated with the disease.

Methods: A targeted sequencing panel and direct sequencing approach were used to identify causative mutations in the index patients and other family members. Read More

Clin J Gastroenterol 2020 Jun 26. Epub 2020 Jun 26.

Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

An aortoesophageal fistula (AEF) is a rare, potentially fatal condition, and esophagectomy is usually performed simultaneously with aortic surgery. However, esophageal reconstruction method has not been established. This case report describes a two-stage operation for AEF after replacement of thoracic aorta for Stanford Type B dissecting aortic aneurysm. Read More

Medicine (Baltimore) 2020 Jun;99(26):e20849

Department of Thoracic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.

Objectives: Ingestion of a foreign body can cause different degrees of damage to esophagus, and several complications are potentially life-threatening if not properly handled. The aortic injury caused by a perforating esophageal foreign body is rare but lethal. The optimal management still remains controversial. Read More

J Endovasc Ther 2020 Jun 26:1526602820938058. Epub 2020 Jun 26.

Department of Cardiovascular Surgery, Morinomiya Hospital, Osaka, Japan.

To analyze the anatomical characteristics of arch aneurysms and evaluate the anatomical feasibility of 4 next-generation stent-grafts with either branched or fenestrated configurations. A retrospective analysis was conducted of 213 patients (mean age 75.0±7. Read More

Arterioscler Thromb Vasc Biol 2020 Jun 25:ATVBAHA120314560. Epub 2020 Jun 25.

From theLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Ibaraki, Japan. (S.J.S., H.T.H., T.S., Y.Y., H.Y.).

Objective: Remodeling of the extracellular matrix plays a vital role in cardiovascular diseases. Using a mouse model of postnatal ascending aortic aneurysms (termed ), we have reported that abnormal mechanosensing led to aneurysm formation in with an upregulation of the mechanosensitive transcription factor, Egr1 (Early growth response 1). However, the role of Egr1 and its upstream regulator(s) in the initiation of aneurysm development and their relationship to an aneurysmal microenvironment are unknown. Read More

Circulation 2020 Jun 25. Epub 2020 Jun 25.

Boston University's and National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA; Department of Medicine, Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, MA; Department of Cardiology, Herlev and Gentofte Hospital, Gentofte, Denmark.

Ruptured aortic aneurysm and aortic dissections are potentially preventable disorders associated with high mortality. Screening of individuals at risk may translate into elective surgical interventions and lowered mortality. It is uncertain if the risk of aortic dilation of varying degrees aggregates within families. Read More

Biosci Rep 2020 Jun 24. Epub 2020 Jun 24.

Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Hankou, China.

Thoracic aortic aneurysm (TAA) has been causing the death of elder people. Myh11 has been reported associated with aortic aneurysm, but there is no specific study on its function on TAA. Here we aimed to explore the function of Myh11 on mouse aortic smooth muscle cells for studying the inner mechanism of TAA. Read More

Eur J Vasc Endovasc Surg 2020 Jun 19. Epub 2020 Jun 19.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Objective: There is controversy about the role of pre-emptive thoracic endovascular aortic repair (TEVAR) in uncomplicated type B aortic dissection (TBAD). The aim was to understand expert opinions and the factors influencing decision making.

Methods: In 2018, surgeons from Australia/New Zealand (ANZ) and Europe (EUR) were contacted to participate in an online survey which comprised questions about preferences for pre-emptive TEVAR, followed by five case scenarios, and two ranking questions for anatomical and technical risk factors respectively. Read More

J Vasc Surg 2020 Jun 18. Epub 2020 Jun 18.

University of Iowa, IA.

Background: The Relay Thoracic Stent-Graft with Plus Delivery System (RelayPlus) (Terumo Aortic, Sunrise, FL) was designed to handle the curvature and tortuosity of the thoracic aorta. It was approved by the Food and Drug Administration (FDA) in 2012 and the post-approval study (PAS) was stopped early due to adequate safety and efficacy data and no difference was identified in experienced versus first-time users of RelayPlus. The purpose of this study is to report real-world outcomes of patients with TAAs and penetrating atherosclerotic ulcers (PAUs) undergoing thoracic endovascular repair (TEVAR) with RelayPlus. Read More

Cardiovasc Drugs Ther 2020 Jun 20. Epub 2020 Jun 20.

Department of Cardiology, China-Japan Friendship Hospital, Beijing, China.

Purpose: Advancing age is the major risk factor for thoracic aortic aneurysm/dissection (TAAD). However, the causative link between age-related molecules and TAAD remains elusive. Here, we investigated the role of Sirtuin 1 (SIRT1, also known as class III histone deacetylase), the best studied member of the longevity-related Sirtuin family, in TAAD development in vivo. Read More

Ann Vasc Surg 2020 Jun 16. Epub 2020 Jun 16.

Division of Vascular and Endovascular Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States.

Objective: Aim was to analyze aortic-related outcomes after diagnosis of aortic dissection (AD), intramural hematoma (IMH), and penetrating aortic ulcer (PAU) from a population-based approach.

Methods: Retrospective review of an incident cohort of AD, IMH, and PAU patients in Olmsted County, MN from 1995-2015. Primary end-point was aortic death. Read More

J Thorac Cardiovasc Surg 2020 May 13. Epub 2020 May 13.

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY.

Objective: An inclusive contemporary analysis of spinal cord injury (SCI) rates in patients undergoing aneurysm repair and the factors associated with complications has not been performed.

Methods: Following a systematic literature search, studies from 2008 to 2018 on repair of descending thoracic aneurysm (DTA) and thoracoabdominal aortic aneurysm (TAAA) were pooled in a meta-analysis performed using the generic inverse variance method. The primary outcome was permanent SCI. Read More

J Cardiovasc Surg (Torino) 2020 Jun 19. Epub 2020 Jun 19.

Vascular Surgery, "Vita-Salute" University School of Medicine, San Raffaele Scientific Institute, Milan, Italy.

Purpose: to report three cases of spinal cord ischemia (SCI) involving the cervical- dorsal level and leading to quadriplegia and quadriparesis, following thoraco-abdominal aortic aneurysm (TAAA) endovascular repair.

Case Reports: A 79-year-old woman with an extent III TAAA was scheduled for a multi-step fenestrated/branched endovascular aortic repair. Immediately after the first step, consisting of standard proximal thoracic stent-graft implantation, she developed quadriplegia that did not resolve despite all therapeutic actions, and died as a consequence on postoperative day 32. Read More

Cardiovasc Intervent Radiol 2020 Jun 16. Epub 2020 Jun 16.

Unit of Vascular Surgery, Department of Surgical Sciences, AOU Città della Salute e della Scienza, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.

Purpose: To report early and mid-term results of post-aortic dissection thoracoabdominal aneurysms (pD-TAAA) treated by complex endografting in three tertiary referral hospitals.

Materials And Methods: A review of all patients with pD-TAAA unfit for open surgery treated with complex endovascular repair from 2012 to 2018 was performed. Simple thoracic endografts (TEVAR) were excluded. Read More

Semin Vasc Surg 2020 Mar 3;32(3-4):111-116. Epub 2020 Apr 3.

Unit of Vascular and Endovascular Surgery, Grande Ospedale Metropolitano, Bianchi-Melacrino-Morelli, Via Giuseppe Melacrino 21-89124, Reggio Calabria, Italy.

We conducted an analysis to assess early and mid-term outcomes of patients after thoracic endovascular aortic repair (TEVAR) for type B thoracic aorta dissection, descending thoracic aneurysm, or traumatic aortic transection. From January 2016 through December 2018, twenty-seven patients (23 male, 4 female, mean age of 57 years) affected by type B dissection (n = 13 [48.2%]), thoracic aneurysm (n = 9 [33. Read More

Vascular 2020 Jun 18:1708538120933516. Epub 2020 Jun 18.

Department of Cardiovascular Surgery, Medical School of Harran University, Şanlıurfa, Turkey.

Objectives: Studies on the short-, medium and long-term effects of flow guiding stents are still limited. In this case report, we present three-year follow-up of the multilayer flow modulator stent in a 55-year-old patient with Crawford Type 2 thoracoabdominal aortic aneurysm.

Methods: A 55-year-old male patient with Crawford Type 2 thoracoabdominal aortic aneurysm had applied to our medical center. Read More

Asian Cardiovasc Thorac Ann 2020 Jun 19:218492320937142. Epub 2020 Jun 19.

Department of Cardiovascular Surgery, Kanazawa University, Kanazawa, Japan.

An 80-year-old woman underwent aortic valve replacement and ascending aortic replacement. Two years later, computed tomography revealed a pseudoaneurysm of the ascending aorta replaced with a prosthesis. The pseudoaneurysm arose from the stump of a side branch of the prosthesis. Read More

Ann Cardiothorac Surg 2020 May;9(3):178-188

Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital of Essen, Essen, Germany.

Background: Over the years, frozen elephant trunk (FET) has become the treatment of choice for multisegmental thoracic aortic disease. This multicenter study presents the evolution of FET results using the E-vita Open hybrid graft with respect to institutional experience and time.

Methods: The data of International E-vita Open registry were studied according to the institutional experience of the participating centers (high- versus low-volume centers) and according to the evolution of FET treatment during time (1 period, 2005-2011 versus 2 period, 2012-2018). Read More

Ann Cardiothorac Surg 2020 May;9(3):164-169

Vascular & Endovascular Surgery, Royal Blackburn Teaching Hospital, Blackburn, UK.

We present a recapitulation of 15 years of experience starting with conception, inception, development, and clinical implementation and application of the E-vita open hybrid graft. Concomitantly, we delve into surgical techniques that shaped our clinical results. Introduced in February 2005, the novel "Essen I Prosthesis", was first-in-human surgically implanted. Read More