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Indian J Anaesth 2019 Apr;63(4):300-303

Department of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, India.

Background And Aims: Myofascial pain syndrome (MPS) is a common cause of chronic musculoskeletal pain, characterised by myofascial trigger points (TPs). TP injection is an established technique for management of MPS. In this study, we analysed the efficacy of myofascial TP injection of lignocaine and the influencing biomechanical factors on MPS. Read More

Pediatr Rheumatol Online J 2019 Mar 20;17(1):11. Epub 2019 Mar 20.

Department of Pediatric Anesthesiology, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue Pittsburgh, Pittsburgh, PA, 15224, USA.

Background: Intra-articular corticosteroid injections (IACI) are frequently used in the treatment of juvenile idiopathic arthritis. There is a paucity of evidence-based research describing methods of pain and anxiety control for this procedure. IACI were mostly performed under general anesthesia for children younger than 13 years old in our institution as of 2014. Read More

Medicine (Baltimore) 2019 Mar;98(10):e14745

Treatment of back pain due to facet joint syndrome has been a challenge for physicians since its recognition ∼80 years ago. Intra-articular injections of steroids, local anesthetics, and phenol have been widely adopted despite their known shortcomings. Recently, intra-articular injection of amniotic membrane-umbilical cord (AMUC) has been utilized in various orthopedic indications, including those involving synovial joints, due to its reported anti-inflammatory properties. Read More

Bone Joint J 2019 Mar;101-B(3):340-347

Department of Orthopedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Aims: Adductor canal block (ACB) has emerged as an alternative to femoral nerve block (FNB) for analgesia after total knee arthroplasty (TKA). The optimal duration of maintenance of the ACB is still questionable. The purpose of this study was to compare the analgesic benefits and physiotherapy (PT) outcomes of single-shot ACB to two different regimens of infusion of the continuous ACB, 24-hour and 48-hour infusion. Read More

Plast Surg Nurs 2019 Jan/Mar;39(1):22-24

Alberto Pérez-García, MD, Department of Plastic Surgery, La Fe University and Polytechnic Hospital, Valencia, Spain. Juan Ramón Esteban-Vico, MD, Department of Plastic Surgery, La Fe University and Polytechnic Hospital, Valencia, Spain. Concepción Lorca-García, MD, Department of Pediatric Surgery, Gregorio Marañón Hospital, Madrid, Spain. Jose María García-Sánchez, MD, Department of Plastic Surgery, La Fe University and Polytechnic Hospital, Valencia, Spain. Luis Miranda Gómez, PhD, Department of Plastic Surgery, La Fe University and Polytechnic Hospital, Valencia, Spain. Abel Llinás Porte, MD, Department of Plastic Surgery, La Fe University and Polytechnic Hospital, Valencia, Spain. Pilar García-Sanz, RN, School of Nursing, University of Valencia, Spain.

This study investigated the use of endonasal infiltrative anesthesia for the management of pain associated with nasal bone fracture reduction. Fifty-two patients with nasal bone fractures were distributed in 2 groups. In the first group, topical endonasal anesthesia and external transcutaneous infiltrative anesthesia were employed. Read More

Open Access Rheumatol 2019 25;11:19-31. Epub 2019 Jan 25.

Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India,

In this narrative review, we overview the recent literature on enthesitis-related arthritis (ERA). For the purpose of our review, we searched Scopus for recent articles on this subject from 2013 onward, including some classic older articles for perspective. ERA is a juvenile idiopathic arthritis (JIA) subtype more common in males, associated in a majority with human leucocyte antigen B27. Read More

Vet Q 2018 Dec;38(1):129-137

a Department of Veterinary Medicine , University of Perugia , Perugia , Italy.

Intra-articular administration of analgesics is performed to ensure good perioperative pain management avoiding undesirable systemic effects. To evaluate the effect of intra-articular injection of tramadol on postoperative pain after arthroscopy in horses and to determine whether tramadol had a local effect. Before the in vivo study, an in vitro test was performed aiming to evaluate the viability of equine chondrocytes after exposure to various concentrations of tramadol. Read More

Pediatr Dermatol 2019 Mar 10;36(2):223-226. Epub 2019 Feb 10.

Pediatric Dermatology, Phoenix Children's Hospital, Phoenix, Arizona.

Parry-Romberg syndrome (PRS) is characterized by hemiatrophy of facial structures, including skin, subcutaneous fat, muscle, bone, and cartilage. Complications associated with PRS include headaches, seizures, and chronic facial pain. Protocol for the treatment of chronic facial pain is not clear; reports on the use of botulinum toxin A injections for pain reduction in adults but not in the pediatric/adolescent population are available. Read More

Medicine (Baltimore) 2019 Feb;98(6):e14406

Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.

Rationale: We present a case of high spinal anesthesia after inadvertent injection of local anesthetics and corticosteroids into the subarachnoid space during attempted epidural injection. Cerebrospinal fluid (CSF) lavage is a suitable method for treatment.

Patient Concerns: A 45-year-old woman presented with posterior thigh, leg, and ankle pain for >6 months and was treated with epidural injection. Read More

Asian J Transfus Sci 2018 Jul-Dec;12(2):105-111

Department of Transfusion Medicine, PGIMER, Chandigargh, India.

Background: Plantar fasciitis (PF) a common chronic musculoskeletal pain routinely diagnosed and treated in rehabilitation practices. When conservative management fails in this degenerative disease, local injections of corticosteroids, platelet rich plasma (PRP), botulinum toxin, extracorporeal shockwave therapy, surgical release are used. In our prospective randomized pilot study we compared the regenerative efficacy of Platelet Rich Plasma vs Kinesiotaping with phonophoresis who were resistant to conservative management of PF. Read More

J Bodyw Mov Ther 2019 Jan 1;23(1):122-137. Epub 2018 Jun 1.

Universidad San Jorge, iPhysio Research Group, Campus Universitario, Autov. A23, km 299, 50830, Villanueva de Gállego, Zaragoza, Spain. Electronic address:

Background: Minimally invasive non-surgical techniques have been widely used worldwide to treat musculoskeletal injuries. Of these techniques, injectable pharmaceutical agents are the most commonly employed treatments, with corticosteroids being the most widely used drugs. The aim of this article is to review current scientific evidence as well as the effectiveness of minimally invasive non-surgical techniques, either alone or combined, for the treatment of plantar fasciitis. Read More

Can Assoc Radiol J 2019 Feb;70(1):37-43

Interventional Musculoskeletal Radiology, Clinical Radiology of Oklahoma, Edmond, Oklahoma, USA.

Back pain is the second most common reason for primary-care physician visits after the common cold. New understanding of the spine pathophysiology and biomechanics led to the development of novel injectable biomaterials to treat those pain generators. Although not all biomaterials are currently ready for common use, there is significant interest by the medical community to invest time, resources, and energy to optimize these injectables. Read More

Toxicon 2019 Mar 17;159:41-44. Epub 2019 Jan 17.

Department of Physical and Rehabilitation Medicine, University of Padova, Via Giustiniani 3, 35128, Padova, Italy.

Complex regional pain syndrome (CRPS) is characterized by hyperalgesia, autonomic and trophic alterations of bones, muscles and skin. It is supported by neurogenic inflammation and impairment of sympathetic nervous system. Botulinum Toxin (BTX) is an option for the management of pain, with level B evidence of efficacy in neuropathic, joint and myofascial pain syndrome. Read More

J Shoulder Elbow Surg 2019 Mar 14;28(3):430-436. Epub 2019 Jan 14.

Townsville Hospital, Douglas, QLD, Australia; Greenslopes Private Hospital, Brisbane, QLD, Australia.

Hypothesis: We aimed to compare the clinical efficacy of a suprascapular nerve block (SSNB) versus subacromial injection (SA) for outpatient treatment of patients with symptomatic rotator cuff tears in a double-blinded, randomized controlled trial using sealed-envelope randomization.

Methods: A total of 42 participants with symptomatic partial- and full-thickness rotator cuff tears quantified by ultrasound or magnetic resonance imaging received either an ultrasound-guided SSNB or SA. The primary outcome measure was shoulder function measured by the modified Constant-Murley (CM) score and the secondary outcome was the pain score measured by a visual analog scale at 2, 6, and 12 weeks after injection. Read More

Ortop Traumatol Rehabil 2018 Oct;20(5):437-443

University and Hospital Department of Traumatology, Orthopaedics and Hand Surgery, Poznan University of Medical Sciences, Poznan, Poland.

Background: Osteoarthritis is an incurable, progressive, degenerative and debilitating joint disease, characterized by pain, stiffness and limitation of joint mobility. Treatment is limited to symptom management and includes pharmaco- and physiotherapy, rehabilitation and surgery.

Objective: To evaluate safety and effectiveness of a selected hyaluronic acid injectable in the treatment of small joint osteoarthritis. Read More

J Vet Med Sci 2019 Mar 15;81(3):411-417. Epub 2019 Jan 15.

Department of Veterinary Surgery and Anestesiology, Faculty of Veterinary Medicine, Universidade do Oeste Paulista, Presidente Prudente, Brazil.

The aim of this study was to evaluate the efficacy and safety of the intra-articular (IA) injection of botulinum toxin type A (BoNT/A) to the management of chronic pain in dogs. In a randomized, controlled, double-blinded study sixteen dogs with osteoarthritis secondary to hip dysplasia were distributed into two groups: 25 IU BoNT/A (BoNT) or saline solution (Control) was administered IA in each affected joint. All dogs received oral supplements (90 days) and carprofen (15 days). Read More

Ghana Med J 2018 Sep;52(3):153-157

Department of Anaesthesia, University of Ilorin Teaching Hospital, Ilorin, Nigeria.

Background: The injection of mixture of plain bupivacaine and triamcinolone acetonide into the sacroiliac joint (SIJ) to relieve chronic low back pain is uncommon in the West African sub-region. The objective of this study was to demonstrate the efficacy or otherwise of fluoroscopic-guided SI joint injection in the management of chronic axial low back pain in Nigeria.

Design: This was a prospective observational interventional study. Read More

Eur J Radiol 2019 Jan 3;110:193-202. Epub 2018 Dec 3.

St Lukes Radiology Oxford Ltd and University of Oxford, UK.

In the modern management of the injured elite athlete, the goals of guided injection therapies have extended beyond simple reduction of pain to enhancement of tissue healing and accelerated return to competition, faster than natural healing can allow. This article will review the injection therapies which are frequently used in elite sports injury management and describe other less commonly used injection therapies that are available to the treating clinician and athlete. The evidence base, where available, for each treatment option will be summarised. Read More

Pain Res Manag 2018 22;2018:7492753. Epub 2018 Nov 22.

Department of Anesthesiology and Reanimation, Republic of Turkey Health Science University, Diyarbakır Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

Background: Diagnosis of lumbar facet joint disease is the sum of the combinations consisting of history, physical activity, and diagnostic imaging frequently including computed tomography and magnetic resonance imaging scans. Prevalence of facet-based chronic low back pain is 15-45%. Intra-articular injections with corticosteroid or medial branch block are traditionally used prevalently in the management of chronic low back pain due to lumbar facet joints. Read More

Pain Pract 2019 03 18;19(3):345-346. Epub 2019 Jan 18.

Department of Anesthesiology, Critical Care and Multidisciplinary Pain Center, Ziekenhuis Oost-Limburg, Genk/Lanaken, Belgium.

JAMA 2018 12;320(24):2564-2579

Department of Clinical Research, Rottapharm Biotech, Monza, Italy.

Importance: Even though osteoarthritis is a chronic and progressive disease, pharmacological agents are mainly studied over short-term periods, resulting in unclear recommendations for long-term disease management.

Objective: To search, review, and analyze long-term (≥12 months) outcomes (symptoms, joint structure) from randomized clinical trials (RCTs) of medications for knee osteoarthritis.

Data Sources And Study Selection: The databases of MEDLINE, Scopus, EMBASE, Web of Science, and the Cochrane Central Register of Controlled Trials were searched until June 30, 2018 (MEDLINE alerts through August 31, 2018) for RCTs of patients with knee osteoarthritis that had treatment and follow-up lasting 1 year or longer. Read More

Cochrane Database Syst Rev 2018 12 20;12:CD012033. Epub 2018 Dec 20.

Department of Anesthesiology, Intensive Care and Pain Medicine, Division of Anesthesiology, Töölö Hospital, Helsinki University and Helsinki University Hospital, Topeliuksenkatu 5, Helsinki, Finland, PB 266 00029.

Background: Inadequate pain management after surgery increases the risk of postoperative complications and may predispose for chronic postsurgical pain. Perioperative ketamine may enhance conventional analgesics in the acute postoperative setting.

Objectives: To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia. Read More

Medicine (Baltimore) 2018 Dec;97(50):e13687

Articular Orthopaedics, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.

Background: The argument on whether extracorporeal shock-wave therapy (ESWT) and corticosteroid injections (CSIs) exert an equivalent pain control or which is the better treatment for plantar fasciitis (PF) in adults remains to be resolved. It is important and necessary to conduct a meta-analysis to make a relatively more credible and overall assessment about which treatment method performs better pain control in treatment of PF in adults.

Methods: From the inception to July 2018, the Embase, PubMed, Web of Science, and Cochrane Library electronic databases were searched for all relevant studies. Read More

Pain Pract 2019 03 7;19(3):344. Epub 2019 Jan 7.

Pain Management Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano, Lugano, Switzerland.

J Okla State Med Assoc 2018 Aug-Sep;111(7):712-713

Saint Anthony Hospital. Family Medicine Residency. Oklahoma City, OK.

Clinical Question: In adults with osteoarthritis of the knee, do conservative management methods such as weight reduction, physical therapy, Tai Chi, non-steroidal anti-inflammatory drugs (NSAIDs), and others provide more and longer pain relief and functionality of the knee, as well as overall well-being, when compared to corticosteroid knee injections?

Answer: Yes. Although there are limited head-to-head trials directly comparing each alternative method to corticosteroid injections, overall evidence appears to indicate conservative methods as being more effective than injections, especially when considering long-term pain relief and functionality. Read More

Clin Ophthalmol 2018 19;12:2347-2362. Epub 2018 Nov 19.

S.C.U. Ophthalmology Unit, "City of Health and Science" University Hospital, Department of Surgical Sciences, University of Turin, Turin, Italy,

The main treatment for pterygium is surgical removal. However, pterygium surgery is concerned with high rates of postoperative recurrence. Predicting factors of recurrence are not fully understood, yet, but they probably depend on a multitude of patient-related, clinical, and/or surgical factors. Read More

Am J Case Rep 2018 Dec 8;19:1453-1458. Epub 2018 Dec 8.

Department of Internal Medicine, Piedmont Athens Regional Medical Center, Athens, GA, USA.

BACKGROUND Thyrotoxic periodic paralysis (TPP) is a rare cause of acute paralysis, which if not promptly recognized and treated, can lead to significant morbidity and mortality. TPP can be precipitated by several factors, including a high carbohydrate diet and exercise. This report is of a rare case of TPP after epidural steroid injection in a young man, with a review of the literature of previous cases. Read More

Clin Orthop Surg 2018 Dec 21;10(4):455-461. Epub 2018 Nov 21.

Department of Orthopedic Surgery, Dankook University College of Medicine, Cheonan, Korea.

Background: Surgical-site, multimodal drug injection has recently evolved to be a safe and useful method for multimodal pain management even in patients with musculoskeletal trauma.

Methods: Fifty consecutive patients who underwent plating for mid-shaft and distal clavicular fractures were included in the study. To evaluate whether surgical-site injections (SIs) have pain management benefits, the patients were divided into two groups (SI and no-SI groups). Read More

J Shoulder Elbow Surg 2019 Mar 28;28(3):596-606. Epub 2018 Nov 28.

Department of Surgery, McMaster University, Hamilton, ON, Canada. Electronic address:

Background: Hyaluronic acid (HA) is an analgesic and chondroprotective agent often used for the nonoperative treatment of osteoarthritis (OA). The effects of HA injections are well studied in the treatment of knee OA, but the effects in glenohumeral OA remain unclear. This study evaluated the efficacy of HA to reduce pain in patients with glenohumeral OA. Read More

R I Med J (2013) 2018 Dec 3;101(10):46-50. Epub 2018 Dec 3.

Division of Sports Medicine, Department of Orthopaedic Surgery, Warren Alpert Medical School, Brown University.

Greater Trochanteric Pain Syndrome (GTPS) is a common cause of lateral hip pain, with an incidence of 1.8 per 1000 patients, most commonly occurring between the fourth and sixth decades of life. When GTPS fails to improve with conservative management, hip abductor insufficiency should be suspected. Read More

Pain Physician 2018 11;21(6):E661-E665

The Orthopedic Clinic Association, Phoenix, AZ.

Background: There is a paucity of literature studying therapeutic intraarticular zygapophyseal (commonly referred to as facet) joint injections in the atraumatic patient population. As a result of this, intraarticular injections have been dismissed as a possible treatment for cervical zygapophyseal joint-mediated pain. Radiofrequency neurotomy (RFN) is currently the accepted treatment for facet joint neck pain. Read More

Pain Physician 2018 11;21(6):515-540

Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Background: Several cell-based therapies have been proposed in recent years the management of low back pain, including the injection of medicinal signaling cells or mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP). However, there is only emerging clinical evidence to support their use at this time.

Objective: To assess the effectiveness of MSCs or PRP injections in the treatment of low back and lower extremity pain. Read More

J Knee Surg 2019 Jan 30;32(1):72-79. Epub 2018 Nov 30.

Department of Anesthesiology and Pain Medicine, Valley Anesthesiology and Pain Consultants, Phoenix, Arizona.

Chronic knee pain is a widely prevalent issue that can have a significant impact on a patient's quality of life. One of the leading causes of chronic knee pain is osteoarthritis. Total knee replacement is often the last and definitive resort for patients with severe symptomatic osteoarthritis after trial of less invasive interventions with failure to achieve symptomatic relief. Read More

Handb Clin Neurol 2018 ;158:431-442

Departments of Rehabilitation Medicine, Orthopaedics and Sports Medicine, and Neurological Surgery, University of Washington, Seattle, WA, United States.

Corticosteroid, hyaluronic acid, and platelet-rich plasma injections are commonly utilized when managing pain and injury in the athlete. Although there is ample scientific literature on these injection types, there is a paucity of evidence guiding the use of any of these modalities in a younger, athletic population. Injection strategies should be used as just one aspect of a detailed and athlete-specific return to sport and rehabilitation plan. Read More

BMC Complement Altern Med 2018 Nov 26;18(1):310. Epub 2018 Nov 26.

Department of Medical Rehabilitation, Faculty of Health Sciences and Technology, University of Nigeria|, Enugu Campus, Enugu State, Nigeria.

Background: Many studies on transcutaneous electrical nerve stimulation (TENS) had been undertaken to explore its pain relieving efficiency on several medicals/surgical conditions but none, specifically, had been carried out to determine the effect it has on post-injection sciatic pain (PISP) which comes about from wrong administration of intramuscular pain. This study aims to assess the effects of TENS in the management of PISP.

Methods: A total of 72 PISP subjects comprising 40 test subjects and 32 control subjects participated in a non-randomized controlled clinical trial in the current study. Read More

J Ultrason 2018 ;18(74):234-239

Oxford University and St Lukes Radiology Oxford Ltd, Oxford, UK.

Diagnosis is crucial in decision-making when treating a patient with shoulder pain. Ultrasound is also very important in the diagnostic and therapeutic pathway, especially when surgery is being considered. This article outlines the diagnostic pathway using the patient's history, physical examination and ultrasound examination. Read More

Knee Surg Sports Traumatol Arthrosc 2019 Jan 15;27(1):5-12. Epub 2018 Nov 15.

Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Purpose: Plantar fasciitis is a very common (lifetime incidence ~ 10%) and long-lasting injury with major impact on daily function. Combining corticosteroid injection and physical training (strength training and stretching) was hypothesized to result in a superior effect compared to each treatment separately.

Methods: A single blinded randomized controlled superiority trial conducted in 2013-2014 with a 2-year follow-up (end Sept 2016). Read More

J Knee Surg 2019 Jan 13;32(1):37-45. Epub 2018 Nov 13.

Division of Sports Medicine, Department of Orthopedics, Rush University Medical Center, Chicago, Illinois.

With average life expectancy and the rising prevalence of obesity, osteoarthritis (OA) is creating an increasingly large financial and physical burden on the U.S. population today. Read More

PLoS One 2018 8;13(11):e0204885. Epub 2018 Nov 8.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Background: An improved understanding of patients' perceived needs for medical services for low back pain (LBP) will enable healthcare providers to better align service provision with patient expectations, thus improving patient and health care system outcomes. Thus, we aimed to identify the existing literature regarding patients' perceived needs for medical services for LBP.

Methods: A systematic scoping review was performed of publications identified from MEDLINE, EMBASE, CINAHL and PsycINFO (1990-2016). Read More

Medicine (Baltimore) 2018 Nov;97(45):e13127

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Taegu, Republic of Korea.

Rationale: Although various oral medications and procedures are applied for managing migraine, their efficacy remains limited. To control migraine that does not respond to conventional treatments, we conducted pulsed radiofrequency (PRF) stimulation to the greater occipital nerve (GON) in 2 patients.

Patient Concerns: Patients 1 and 2 complained of chronic throbbing, pulsating, and tight headaches. Read More

Medicine (Baltimore) 2018 Nov;97(44):e13049

Department of Orthopedics, Second Affiliated Hospital of the Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine.

Background: Knee osteoarthritis (KOA) is a progressive joint disease involving intraarticular and periarticular structures. In recent years, there has been increasing interest in the use of autologous growth factors, such as intraarticular injections of platelet-rich plasma (PRP), to treat KOA. It is necessary to update the research and reevaluate the efficacy and safety of PRP to provide up-to-date evidence for KOA management. Read More

PM R 2018 Oct 24. Epub 2018 Oct 24.

Department of Structural Biology and Anatomy, Department of Physical Medicine and Rehabilitation, 1300 Morris Park Avenue, Bronx, NY 10461.

Background: Neck pain is one of the most common causes of chronic pain and the fourth leading cause of disability worldwide; it is estimated that between 36% to 67% of this pain is due to facet arthropathy. For patients who have pain refractory to conservative treatments literature supports management with diagnostic cervical medial branch blocks (cMBBs) to identify the associated facet innervation as the source of pain followed by therapeutic radiofrequency ablation (RFA) of the identified nerves. Cervical RFA has good published outcomes, but the procedure is dependent upon the specificity of the diagnostic block to achieve maximal success. Read More

BMC Vet Res 2018 Oct 23;14(1):318. Epub 2018 Oct 23.

Department of Pathobiology, University of Guelph, 50 Stone Road E, Guelph, ON, N1G 2W1, Canada.

Background: Surgical castration is a painful procedure, performed routinely on commercial pig farms to prevent boar taint and reduce aggression. The objectives of this study were to assess the efficacy of 0.04 mg/kg buprenorphine (BUP) in reducing pain in castrated piglets, using behavioral indicators and vocalization analysis. Read More

FP Essent 2018 Oct;473:17-20

Department of Family and Community Medicine at University of Kansas School of Medicine-Wichita, 1010 North Kansas, Wichita, KS 67214-3199.

Tension-type headache (TTH) is the most common primary headache disorder, with a worldwide lifetime prevalence of 46% to 78%. TTH causes greater disability and accounts for more missed work days than migraine. The etiology of TTH is thought to be multifactorial, involving genetic and environmental factors. Read More

J Dent Child (Chic) 2018 May;85(2):51-57

Department of Dental Public Health and Pediatric Dentistry, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, Calif., USA.

The purpose of this study was to clinically compare injection pain experience in children using three methods. This was a randomized clinical trial conducted among 150 children (81 girls, 69 boys), from seven to 14 years of age, who required operative dental treatment. Fifty patients were randomized into one of three groups: DentalVibe, manual stimulation, or no stimulation (control). Read More

Taiwan J Obstet Gynecol 2018 Oct;57(5):654-658

Department of Obstetrics and Gynecology, Nowon Eulji Medical Center, Eulji University, Seoul, Republic of Korea. Electronic address:

Objective: Although laparoscopic hysterectomy, a worldwide popular surgery, ensures faster recovery and less postoperative pain than with laparotomic hysterectomy, immediate pain control still improving postoperative care. We introduce an effective method, intraoperative injection of ropivacaine into both uterosacral ligaments, to control immediate postoperative pain.

Materials And Methods: We performed a prospective, double-blind, and randomized study. Read More

BMC Endocr Disord 2018 Oct 13;18(1):71. Epub 2018 Oct 13.

The Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, UK.

Background: When children with type 1 diabetes approach adolescence, they are encouraged to become more involved in diabetes self-management. This study explored the challenges pre-adolescent children encounter when self-managing diabetes and the factors which motivate and enable them to take on new diabetes-related tasks. A key objective was to inform the support offered to pre-adolescent children. Read More

Medicine (Baltimore) 2018 Oct;97(41):e12791

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

A previous study showed that transforaminal balloon adhesiolysis via the safe triangle was effective in lumbar spinal stenosis. However, retrodiscal pathology is difficult to treat with this method. Therefore we attempted retrodiscal balloon adhesiolysis via Kambin's triangle. Read More

Worldviews Evid Based Nurs 2018 Dec 11;15(6):464-470. Epub 2018 Oct 11.

Child Endocrinology Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey; Birgul Kirel.

Background: Repeated injections may prevent children from performing insulin administration (skip dosing) and may cause anxiety.

Aims: To compare the effect of ShotBlocker and the combination of vibration and cold application (Buzzy) in reducing pain during insulin administration in children.

Methods: This research was designed as a randomized controlled experimental study. Read More

Pain Physician 2018 09;21(5):E501-E508

Algology Division, Department of Anesthesia, Akdeniz University, Antalya, Turkey.

Background: Percutaneous epidural adhesiolysis and neuroplasty (PEAN) has been proven to be safe and effective in treating different spine pathologies, in particular post lumbar surgery syndrome (PLSS).

Objectives: The purpose of this study was to compare the efficacy and complication rates of the 3 different PEAN anatomical approaches (caudal, S1 foraminal, and L5-S1 transforaminal) used to treat PLSS.

Study Design: This study used a case control, blind study. Read More