117,121 results match your criteria Therapeutic Exercise


Progressive Multicomponent Intervention for Older Adults in Home Health Settings Following Acute Hospitalization: Randomized Clinical Trial Protocol.

Phys Ther 2019 Apr 20. Epub 2019 Apr 20.

Physical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Mail Stop C244, 13121 East 17th Avenue, Room 3116, Aurora, CO 80045 (USA) and Veterans Affairs Geriatric Research, Education and Clinical Center, Denver, Colorado.

Background: Hospitalization is a profound contributor to functional loss for older adults. Many modifiable risk factors (ie, weakness) may persist after hospitalization, representing portents of poor health, re-hospitalization, or death. Older adults frequently receive home health (HH) care after hospitalization to manage functional deficits that have worsened during hospital stays. Read More

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https://academic.oup.com/ptj/advance-article/doi/10.1093/ptj
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http://dx.doi.org/10.1093/ptj/pzz069DOI Listing
April 2019
1 Read

Study Protocol for a Prospective, Multicenter, Randomized, Open-Label, Parallel-Group Clinical Trial Comparing the Efficacy and Safety of a Needle-Free Insulin Injector and a Conventional Insulin Pen in Controlling Blood Glucose Concentrations in Chinese Patients with Type 2 Diabetes Mellitus (The FREE Study).

Adv Ther 2019 Apr 19. Epub 2019 Apr 19.

Department of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China.

Introduction: China has the largest number of diabetic patients in the world. In the past 2 decades, the prevalence of diabetes in China has increased dramatically, and the current status of diabetes control in the diabetic population is not satisfactory. Although insulin is currently recognized in diabetes treatment guidelines as the therapeutic option for patients not adequately controlled by diet/exercise and oral agents, the proportion of patients with type 2 diabetes using insulin is still very low, and the time when insulin therapy is initiated is relatively late. Read More

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http://dx.doi.org/10.1007/s12325-019-00951-4DOI Listing

Rehabilitation with a combination of scalp acupuncture and exercise therapy in spastic cerebral palsy.

Complement Ther Clin Pract 2019 May 7;35:296-300. Epub 2019 Mar 7.

Children Rehabilitation Center of Huai'an Maternal and Child Health Care Hospital, No.104 People South Road, Huai'an, 223002, China.

Purpose: To use Traditional Chinese Medicine (TCM) and Western approaches to improve gross motor function and activities of daily living (ADL) in children with spastic cerebral palsy.

Methods: Children were randomly divided into a treatment group, which received scalp acupuncture combined with exercise therapy and conventional rehabilitation training, and a control group, which received conventional rehabilitation training alone. Study subjects' gross motor function (gross motor function measure-88 [GMFM-88]) and ADL were evaluated before and after therapy. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.03.002DOI Listing

Acupuncture therapy improves health-related quality of life in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Complement Ther Clin Pract 2019 May 2;35:208-218. Epub 2019 Mar 2.

Division of Pulmonary Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan; School of Medicine, Tzu-Chi University, Hualien, Taiwan. Electronic address:

Background: Chronic obstructive pulmonary disease (COPD) is highly prevalent around the world and has a large impact on its patients, leading to a poor health-related quality of life (HRQL) and exercise capacity. Even under optimal medications, there are still many patients with poor HRQL. Body acupuncture therapy (BAT) is a non-invasive and a popular therapy. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.02.016DOI Listing

Conservative Management and Rehabilitation in the Older Runner With Knee Osteoarthritis: An Evidence-Based Review.

Am J Phys Med Rehabil 2019 May;98(5):416-421

From the Physical Medicine and Rehabilitation Department, MossRehab, Elkins Park, Pennsylvania (BC); and Physical Medicine, Rehabilitation and Sports Medicine Department, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico (FS, WM).

Osteoarthritis is an age-related condition that commonly affects the middle-aged and elderly population including individuals who continue to pursue an active and athletic lifestyle. Running is an easily accessible activity with many health benefits; thus, it is becoming a popular form of exercise, even in older individuals. Studies evaluating the correlation between running and osteoarthritis show conflicting results; however, most studies show an increased risk of osteoarthritis in runners with a combination of modifiable and nonmodifiable risk factors. Read More

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http://dx.doi.org/10.1097/PHM.0000000000001082DOI Listing

A Scoping Review of Nonpharmacological Interventions to Reduce Disability in Older Adults.

Gerontologist 2019 Apr 19. Epub 2019 Apr 19.

Department of Occupational Therapy, School of Health and Rehabilitation Science, Pennsylvania.

Background And Objectives: Minimizing disability is critical to reduce the costly health care associated with disability and maintain quality of life into old age. We examined the effect sizes of nonpharmacological intervention studies in reducing disability and explored the active ingredients of interventions.

Research Design And Methods: A scoping review was conducted via PubMed, PsycINFO, and CINAHL databases. Read More

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https://academic.oup.com/gerontologist/advance-article/doi/1
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http://dx.doi.org/10.1093/geront/gnz026DOI Listing
April 2019
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Heat therapy vs. supervised exercise therapy for peripheral arterial disease: a 12-week randomized, controlled trial.

Am J Physiol Heart Circ Physiol 2019 Apr 19. Epub 2019 Apr 19.

School of Physical Education, Sport and Exercise Sciences, University of Otago, New Zealand.

Peripheral arterial disease (PAD) is characterized by lower limb atherosclerosis impairing blood supply and causing walking-induced leg pain, or claudication. Adherence to traditional exercise training programs is poor due to these symptoms, despite exercise being a mainstay of conservative treatment. Heat therapy improves many cardiovascular health outcomes, so this study tested if this was a viable alternative cardiovascular therapy for PAD patients. Read More

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https://www.physiology.org/doi/10.1152/ajpheart.00151.2019
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http://dx.doi.org/10.1152/ajpheart.00151.2019DOI Listing
April 2019
1 Read

Effects of moving cupping therapy on hip and knee range of movement and knee flexion power: a preliminary investigation.

J Man Manip Ther 2019 Apr 19:1-8. Epub 2019 Apr 19.

a Sport Exercise and Rehabilitation , Northumbria University , Newcastle upon tyne , England.

Cupping therapy has become more popular in the sports setting because of its simplicity in application, minimal adverse effects, and reduction in pain and muscle tenderness, yet there is little research on its effectiveness for range of movement and power.

Objectives: The primary aim of this study was to investigate if a single session of moving cupping to the posterior aspect of the lower limb effects hip and knee range of movement and knee flexion power. The secondary aim was to consider participants' views and perceptions of moving cupping therapy. Read More

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http://dx.doi.org/10.1080/10669817.2019.1600892DOI Listing

Effects of Exercise Combined with Finasteride on Hormone and Ovarian Function in Polycystic Ovary Syndrome Rats.

Int J Endocrinol 2019 13;2019:8405796. Epub 2019 Mar 13.

Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Exercise can reduce androgen and insulin levels in polycystic ovary syndrome (PCOS) patients. Finasteride is also presumed to improve the developing follicle environment. Therefore, the aim of this study was to observe the effects of the combination of exercise and finasteride therapy on hormone levels and ovarian morphology in rats with polycystic ovary syndrome. Read More

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http://dx.doi.org/10.1155/2019/8405796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436361PMC

Physical Exhaustion Induced Variations in Event-Related Potentials and Cognitive Task Performance in Young Adults.

Ann Neurosci 2018 Dec 14;25(4):299-304. Epub 2019 Jan 14.

Department of Pharmacology, K.M.C. Manipal, Manipal University, Manipal, India.

Background/aims: Physical exhaustion is not always peripheral, and it is the brain that causes the sensation of fatigue either due to decrease of metabolic resources or due to central activation process that regulates attention and performance. This study was undertaken to observe the variations in event-related potentials (ERPs) and cognitive performance after an exhausting physical exercise.

Methods: A total of 60 healthy young adult subjects were included in the study. Read More

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https://www.karger.com/Article/FullText/487845
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http://dx.doi.org/10.1159/000487845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470344PMC
December 2018
1 Read

Therapeutic Use Exemptions (TUEs) are essential in sport: but there is room for improvement.

Authors:
Ken Fitch

Br J Sports Med 2019 Apr 18. Epub 2019 Apr 18.

Faculty of Human Sciences-Sport, Exercise and Health, University of Western Australia, Crawley, WA 6009, Australia

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http://bjsm.bmj.com/lookup/doi/10.1136/bjsports-2018-100113
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http://dx.doi.org/10.1136/bjsports-2018-100113DOI Listing
April 2019
1 Read

Nonoperative Treatment of Rotator Cuff Disease With Platelet-Rich Plasma: A Systematic Review of Randomized Controlled Trials.

Arthroscopy 2019 Apr 15. Epub 2019 Apr 15.

Sports Surgery Clinic, Dublin, Ireland.

Purpose: To perform a systematic review of randomized controlled trials on the use of platelet-rich plasma (PRP) for nonoperative treatment of rotator cuff disease.

Methods: Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, 2 reviewers independently screened the MEDLINE, Embase, and Cochrane Library databases for prospective, randomized controlled trials comparing PRP with a control in the nonoperative treatment of chronic rotator cuff disease for inclusion. Clinical data were extracted and evaluated. Read More

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http://dx.doi.org/10.1016/j.arthro.2018.10.115DOI Listing

Video-assisted thoracoscopic lobectomy: which patients require postoperative physiotherapy?

Physiotherapy 2019 Jan 11. Epub 2019 Jan 11.

Department of Thoracic Surgery, Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham B9 5SS, UK. Electronic address:

Objectives: Following major thoracic surgery physiotherapy is recommended to improve reduced lung volume, aid secretion clearance, and improve mobility, however, in many centres physiotherapy provision is variable following minimally invasive video-assisted thoracoscopic surgery (VATS). The objective of this study was to observe frequency of problems potentially amenable to physiotherapy following VATS lobectomy, and to identify associated baseline factors of patients in whom physiotherapy may be beneficial.

Methods: A prospective observational study was performed including all consecutive cancer patients undergoing VATS lobectomy in a regional centre over 4years (2012-2016). Read More

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http://dx.doi.org/10.1016/j.physio.2019.01.001DOI Listing
January 2019
2 Reads

The influence of isokinetic peak torque and muscular power on the functional performance of active and inactive community-dwelling elderly: a cross-sectional study.

Braz J Phys Ther 2019 Apr 5. Epub 2019 Apr 5.

Postgraduate Program in Rehabilitation Sciences, Universidade de Brasília (UnB) - Campus Ceilândia, Brasília, DF, Brazil. Electronic address:

Objective: To verify the importance of the isokinetic muscular torque and power of knee extensors and flexors on the functional performance of active and inactive elderly women.

Methods: A cross-sectional observational study was conducted with 116 community-dwelling women (≥60 years old) without severe cognitive and/or motor dysfunction. Isokinetic muscle function was measured by peak torque and muscle power at 60°/s (5 repetitions) and 180°/s (15 repetitions), respectively. Read More

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http://dx.doi.org/10.1016/j.bjpt.2019.03.003DOI Listing

Comparison of sedentary behaviour questionnaires in people with multiple sclerosis.

Disabil Rehabil 2019 Apr 18:1-8. Epub 2019 Apr 18.

a School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham , Birmingham , UK.

Background: People with multiple sclerosis are at risk of developing co-morbidities associated with sedentary behaviour. Despite an increase in studies examining sedentary behaviour in multiple sclerosis, researchers have not yet examined the appropriateness of the content or format of questionnaires assessing sedentary behaviour in multiple sclerosis.

Objective: Evaluate perceptions of sedentary behaviour questionnaires for people with multiple sclerosis. Read More

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https://www.tandfonline.com/doi/full/10.1080/09638288.2019.1
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http://dx.doi.org/10.1080/09638288.2019.1597179DOI Listing
April 2019
1 Read

Aerobic Exercise Training with Brisk Walking Increases Intestinal Bacteroides in Healthy Elderly Women.

Nutrients 2019 Apr 17;11(4). Epub 2019 Apr 17.

Department of Environmental Physiology for Exercise, Osaka City University Graduate School of Medicine, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka-shi, Osaka 558-8585, Japan.

This study examined the effect of an exercise intervention on the composition of the intestinal microbiota in healthy elderly women. Thirty-two sedentary women that were aged 65 years and older participated in a 12-week, non-randomized comparative trial. The subjects were allocated to two groups receiving different exercise interventions, trunk muscle training (TM), or aerobic exercise training (AE). Read More

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http://dx.doi.org/10.3390/nu11040868DOI Listing

Physical activity sustains memory retrieval in dopamine-depleted mice previously treated with L-Dopa.

Behav Brain Res 2019 Apr 15:111915. Epub 2019 Apr 15.

Department of Neurology, Charité-Universitätsmedizin, Charitéplatz 1, 10117, Berlin, Germany. Electronic address:

The neurodegenerative disorder Parkinson's disease affects motor abilities as well as cognition. The gold standard therapy is L-Dopa, which mainly restores motor skills. Therefore, we require additional interventions to sustain cognitive functions in Parkinson's disease. Read More

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http://dx.doi.org/10.1016/j.bbr.2019.111915DOI Listing

An update on heart disease risk associated with testosterone boosting medications.

Expert Opin Drug Saf 2019 Apr 18. Epub 2019 Apr 18.

b Andrology, Female Endocrinology and Gender Incongruence Unit, Department of Experimental, Clinical and Biomedical Sciences , University of Florence , Florence , Italy.

Introduction: The cardiovascular (CV) safety of testosterone replacement therapy (TRT) remains a crucial issue in the management of subjects with late onset hypogonadism. The authors systematically reviewed and discussed the available evidence focusing our analysis on heart related issues. Areas covered: All the available data from prospective observational studies evaluating the role endogenous T levels on the risk of acute myocardial infarction (AMI) were collected and analyzed. Read More

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http://dx.doi.org/10.1080/14740338.2019.1607290DOI Listing

ENDOPLASMIC RETICULUM STRESS AND UNFOLDED PROTEIN RESPONSE IN DIAPHRAGM MUSCLE DYSFUNCTION OF PATIENTS WITH STABLE CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

J Appl Physiol (1985) 2019 Apr 18. Epub 2019 Apr 18.

Pulmonology Department-Muscle and Respiratory System Research Unit (URMAR), CEXS, IMIM-Hospital del Mar, UPF, CIBERES, Spain.

Respiratory muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Chronic contractile activity induces endoplasmic reticulum (ER) stress and unfolded protein response UPR in animals (animals and humans). We hypothesized that the respiratory muscle dysfunction associated with COPD may upregulate ER stress and UPR expression in diaphragm of stable patients with different degrees of airway obstruction and normal body composition. Read More

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http://dx.doi.org/10.1152/japplphysiol.00670.2018DOI Listing
April 2019
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Anti-apoptotic and Mitochondrial Biogenetic Effects of Exercise Training on Ovariectomized Hypertensive Rat Hearts.

J Appl Physiol (1985) 2019 Apr 18. Epub 2019 Apr 18.

School of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taiwan.

Background: This study was to investigate the effects of exercise training on anti-apoptotic pathways and mitochondrial biogenesis in ovariectomized hypertensive rats.

Methods: Histopathological analysis, TUNEL assay and Western blotting were performed on the excised hearts from female spontaneously hypertensive rats (SHR), which were divided into a sham-operated sedentary hypertensive (SHR-S), a sedentary hypertensive ovariectomized (SHR-O), and hypertensive ovariectomized rats which underwent treadmill exercise training (SHR-OT, 60 min/day, 5 days/week) for 8 weeks, along with normotensive Wistar Kyoto rats (WKY).

Results: When compared with the WKY group, the SHR-S group exhibited decreased protein levels of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitochondrial OPA-1 (mitochondrial biogenesis) and decreased further in the SHR-O group. Read More

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https://www.physiology.org/doi/10.1152/japplphysiol.00038.20
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http://dx.doi.org/10.1152/japplphysiol.00038.2019DOI Listing
April 2019
4 Reads

Acupuncture and Vitamin D for the Management of Aromatase Inhibitor-Induced Arthralgia.

Curr Oncol Rep 2019 Apr 17;21(6):51. Epub 2019 Apr 17.

Houston Methodist Cancer Center/Weill Cornell Medicine, Outpatient Tower, Floor 24, 6445 Main Street, Houston, TX, 77030, USA.

Purpose Of Review: Aromatase inhibitor-induced arthralgia (AIA) is a very common syndrome which significantly affects breast cancer survivors' quality of life, and it often leads to non-compliance with aromatase inhibitor (AI) therapy. However, the treatment of AIA remains a clinical challenge. Here, we will review the current data for acupuncture and vitamin D in the management of AIA. Read More

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http://link.springer.com/10.1007/s11912-019-0795-1
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http://dx.doi.org/10.1007/s11912-019-0795-1DOI Listing
April 2019
2 Reads

VALIDITY OF HAND-HELD DYNAMOMETRY IN MEASURING QUADRICEPS STRENGTH AND RATE OF TORQUE DEVELOPMENT.

Int J Sports Phys Ther 2019 Apr;14(2):180-187

Physical Therapy Department, Creighton University, Omaha, NE, USA.

Background: A hand-held dynamometer (HHD) offers a reliable and valid method to quantify quadriceps strength in a clinical environment. While measures of peak strength provide functional insights, most daily activities are performed quickly and do not require maximum strength. Rate of torque development (RTD) measures better reflect both the demands of daily activity and athletic movements. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449009PMC

Does ISWT evaluate maximal exercise capacity in subjects with severe asthma?

Respirology 2019 Apr 17. Epub 2019 Apr 17.

Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13563
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http://dx.doi.org/10.1111/resp.13563DOI Listing
April 2019
2 Reads

Proprioceptive Training and Outcomes of Patients With Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials.

J Athl Train 2019 Apr 17. Epub 2019 Apr 17.

Integrated Sports Science Research Laboratory, Yonsei University, Seoul, Republic of Korea.

Objective: To describe the effects of proprioceptive training on pain, stiffness, function, and functional test outcomes among patients with knee osteoarthritis (OA).

Data Sources: All studies completed from 1946 to 2017 were obtained from 4 databases (PubMed, MEDLINE, CINAHL, and SPORTDiscus).

Study Selection: Three reviewers independently identified appropriate studies and extracted data. Read More

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http://dx.doi.org/10.4085/1062-6050-329-17DOI Listing

Cardiovascular Disease: Chronic Venous Insufficiency and Varicose Veins.

FP Essent 2019 Apr;479:16-20

Womack Army Medical Center Department of the Army, WAMC Stop A 2817 Reilly Rd, Ft Bragg, NC 28310-7301.

Chronic venous insufficiency (CVI) results from long-term venous hypertension in the legs caused by venous obstruction, venous valve incompetency, muscle pump dysfunction, or a combination of these. CVI occurs in 9.4% of men and 6. Read More

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April 2019
2 Reads

Cardiovascular Disease: Lower Extremity Peripheral Artery Disease.

FP Essent 2019 Apr;479:11-15

Womack Army Medical Center Department of the Army, WAMC Stop A 2817 Reilly Rd, Ft Bragg, NC 28310-7301.

Lower extremity peripheral artery disease (PAD) refers to atherosclerotic disease that involves the iliac, femoral, or more distal arteries of the lower extremities. This condition affects 8 to 12 million Americans. Risk factors include advanced age, hypertension, dyslipidemia, diabetes, and cigarette smoking. Read More

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April 2019
2 Reads

Effects of eccentric exercise in pressure pain threshold in subjects with functional ankle equinus condition.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):384-387. Epub 2019 Apr 11.

School of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, Madrid, Spain.

Stretching exercises are widely used by the population before sporting activities. One of the most common technique is eccentric exercise. Here, we made a clinical examination of 98 subjects with equinus condition before activity and after 30 min of running (49 participants with previous eccentric exercise and 49 with no previously eccentric exercise). Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.65.3.384DOI Listing
March 2019
2 Reads

Increased levels of plasma IL-1b and BDNF can predict resistant depression patients.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):361-369. Epub 2019 Apr 11.

Dante Pazzanese Institute of Cardiology, São Paulo, SP, Brasil.

Background: There is no strong evidence on the link between inflammatory profile and pattern of drug treatment response in depressive patients that could result in Coronary Artery Disease occurrence.

Objective: This study aimed to compare the subclinical atherosclerosis markers, inflammatory profile, and BDNF production in Resistant Depression (RD) or Bipolar Affective Disorder (BAD) patients under conventional treatment.

Methods: The population evaluated was comprised of 34 RD, 43 BAD, and 41 controls. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.65.3.361DOI Listing
March 2019
2 Reads

Pedaling-Based Protocol Superior to a 10-Exercise, Non-Pedaling Protocol for Postoperative Rehabilitation After Total Knee Replacement: A Randomized Controlled Trial.

J Bone Joint Surg Am 2019 Apr;101(8):688-695

Bond University, Robina, Queensland, Australia.

Background: Despite the routine use of physical therapy in the immediate and early postoperative phase for patients who undergo total knee replacement (TKR), there is a paucity of research into the optimal exercise protocols in both the acute inpatient setting and early period after discharge. Pedaling has often been recommended by clinicians after TKR for rehabilitation, but to our knowledge, there has been no investigation into its utility in the acute postoperative setting. Therefore, we performed a randomized controlled trial evaluating the efficacy of pedaling in the acute postoperative period. Read More

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http://dx.doi.org/10.2106/JBJS.18.00898DOI Listing
April 2019
1 Read

Diastolic dyssynchrony and its exercise-induced changes affect exercise capacity in patients with heart failure with reduced ejection fraction.

Cardiol J 2019 Apr 17. Epub 2019 Apr 17.

Department of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital in Kraków, Prądnicka 80, 31-202 Krakow, Poland.

Background: Left ventricular (LV) diastolic dyssynchrony is common in patients with heart failure with reduced ejection fraction (HFREF). Little is known however, about its pathophysiology and clinical effects. Herein is hypothesized that presence of diastolic dyssynchrony at rest or at exercise may importantly contribute to HF symptoms. Read More

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http://dx.doi.org/10.5603/CJ.a2019.0032DOI Listing
April 2019
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Higher amounts of Sedentary Time are Associated with Short Sleep Duration and Poor Sleep Quality in Postmenopausal Women.

Sleep 2019 Apr 17. Epub 2019 Apr 17.

Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO.

Study Objectives: To evaluate the associations between sedentary time, total (total-PA), light (light-PA), moderate (MOD-PA), and vigorous (VIG-PA) physical activity with indices of sleep in postmenopausal women.

Methods: Baseline self-reported data from the Women's Health Initiative Observational Study (n=75,074) were used in this cross-sectional analysis. Total-PA, light-PA, MOD-PA, and VIG-PA were categorized by metabolic equivalents of the activity [MET-hour (hr)/week (wk)] and were estimated using validated questionnaires. Read More

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http://dx.doi.org/10.1093/sleep/zsz093DOI Listing
April 2019
1 Read

Care quality for rheumatoid arthritis patients in Quebec.

Int J Rheum Dis 2019 Apr 16. Epub 2019 Apr 16.

Division of Clinical Epidemiology, Research Institute of the McGill University Health Center, Montreal, Quebec, Canada.

Aim: The aims of this study were to: (a) measure the proportion of CARTaGENE rheumatoid arthritis (RA) patients fulfilling pre-specified quality indicators (ie disease-modifying antirheumatic drug [DMARD] use, regular follow up, use of folate supplementation, use of vitamin D and calcium, exercise and smoking status); and (b) examine variation in DMARD use with respect to patient age, sex, education and income.

Methods: A cohort of RA patients was constructed based on the CARTaGENE survey and health administrative database. CARTaGENE is a large, established, population-based study which recruited 19 995 participants from four metropolitan regions in Quebec. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.13
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http://dx.doi.org/10.1111/1756-185X.13580DOI Listing
April 2019
3 Reads

Exploring thoughts about pain and pain management: Interviews with South Asian community members in the UK.

Musculoskeletal Care 2019 Apr 17. Epub 2019 Apr 17.

Staffordshire University, Stoke on Trent, UK.

Objective: This research sought to explore the pain management beliefs of members of the South Asian community living in the UK. In particular, their understanding of the key components of cognitive behavioural therapy (CBT) informed pain management programmes (PMPs) was explored.

Methods: Snowball sampling was used to recruit 10 participants from a South Asian background for interview. Read More

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http://dx.doi.org/10.1002/msc.1400DOI Listing
April 2019
1 Read

HbA1c and retinal arteriolar narrowing in children with type 1 diabetes: the DEAR-Kids study.

Pediatr Diabetes 2019 Apr 16. Epub 2019 Apr 16.

Department of General Paediatrics, Adolescent Medicine and Neonatology, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Background/objective: Microvascular alterations play a key role in the development of diabetes complications. Retinal vessel analysis is a unique method to examine microvascular changes in brain derived vessels.

Subjects/methods: 67 pediatric and adolescent type 1 diabetes patients and 58 healthy control persons (mean age 12. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.12858
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http://dx.doi.org/10.1111/pedi.12858DOI Listing
April 2019
2 Reads

AAV9 Gene Replacement Therapy for Respiratory Insufficiency in Very-long Chain Acyl-CoA Dehydrogenase Deficiency.

J Inherit Metab Dis 2019 Apr 17. Epub 2019 Apr 17.

Department of Pediatrics, Duke University, Durham, NC.

Very-long chain acyl-CoA dehydrogenase (VLCAD) deficiency (VLCADD) is an autosomal recessive disorder of fatty acid oxidation. Fatty acids are a major source of energy during catabolic stress, so the abscense of VLCAD can result in a metabolic crises and respiratory insufficiency. The etiology of this respiratory insufficiency is unclear. Read More

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http://dx.doi.org/10.1002/jimd.12101DOI Listing
April 2019
1 Read

Lipidome Abnormalities and Cardiovascular Disease Risk in HIV Infection.

Curr HIV/AIDS Rep 2019 Apr 16. Epub 2019 Apr 16.

School of Health and Rehabilitation Sciences, Division of Medical Laboratory Science, Ohio State University College of Medicine, 453 W. 10th Ave. 535A Atwell Hall, Columbus, OH, 43210, USA.

Purpose Of Review: Human immunodeficiency virus (HIV) infection and its treatment with antiretroviral therapy (ART) are associated with lipid abnormalities that may enhance cardiovascular disease risk (CVD).

Recent Findings: Chronic inflammation persists in HIV+ individuals, and complex relationships exist among lipids and inflammation, as immune activation may be both a cause and a consequence of lipid abnormalities in HIV infection. Advances in mass spectrometry-based techniques now allow for detailed measurements of individual lipid species; improved lipid measurement might better evaluate CVD risk compared with the prognostic value of traditional assessments. Read More

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http://link.springer.com/10.1007/s11904-019-00442-9
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http://dx.doi.org/10.1007/s11904-019-00442-9DOI Listing
April 2019
2 Reads

Focal scar and diffuse myocardial fibrosis are independent imaging markers in repaired tetralogy of Fallot.

Eur Heart J Cardiovasc Imaging 2019 Apr 16. Epub 2019 Apr 16.

Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Avenue de Magellan, 33604 Pessac, France.

Aims: To identify the correlates of focal scar and diffuse fibrosis in patients with history of tetralogy of Fallot (TOF) repair.

Methods And Results: Consecutive patients with prior TOF repair underwent electrocardiogram, 24-h Holter, transthoracic echocardiography, exercise testing, and cardiac magnetic resonance (CMR) including cine imaging to assess ventricular volumes and ejection fraction, T1 mapping to assess left ventricular (LV) and right ventricular (RV) diffuse fibrosis, and free-breathing late gadolinium-enhanced imaging to quantify scar area at high spatial resolution. Structural imaging data were related to clinical characteristics and functional imaging markers. Read More

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http://dx.doi.org/10.1093/ehjci/jez068DOI Listing
April 2019
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Attitudes and perceived barriers toward healthy lifestyle behaviors in Jordanian adolescents: a developing country perspective.

Adolesc Health Med Ther 2019 28;10:39-47. Epub 2019 Mar 28.

Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.

Background And Aims: There is an urgent need to address the role of healthy diet and behaviors promoting health among school adolescents in order to tailor appropriate interventions in Jordanian schools. This study aims to evaluate the reliability and validity of the Arabic version of Students As LifeStyle Activists (SALSA) survey alongside Jordanian adolescents' attitudes and perceived barriers to healthy eating and physical activity.

Methods: This study uses baseline data from a randomized controlled trial recruiting school students from 29 male and 27 female public high schools that have grades 7 and 8. Read More

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http://dx.doi.org/10.2147/AHMT.S181001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445189PMC
March 2019
1 Read

The effectiveness of high intensity intermittent training on metabolic, reproductive and mental health in women with polycystic ovary syndrome: study protocol for the iHIT- randomised controlled trial.

Trials 2019 Apr 16;20(1):221. Epub 2019 Apr 16.

Institute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.

Background: Polycystic ovary syndrome (PCOS) is a reproductive-metabolic condition. Insulin resistance is a hallmark of PCOS and is related to increased hyperandrogenism that drives inherent metabolic, reproductive and psychological features of the syndrome. Insulin resistance in women with PCOS is managed by weight loss, lifestyle interventions (i. Read More

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http://dx.doi.org/10.1186/s13063-019-3313-8DOI Listing
April 2019
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Efficacy and Feasibility of Pain management and Patient Education for Physical Activity in Intermittent claudication (PrEPAID): protocol for a randomised controlled trial.

Trials 2019 Apr 16;20(1):222. Epub 2019 Apr 16.

Department of Physiotherapy and Paramedicine, School of Health and Life Sciences, Glasgow Caledonain University, Glasgow, UK.

Background: Physical activity (PA) improves functional capacity and quality of life and provides secondary prevention benefits in individuals with peripheral arterial disease (PAD) and intermittent claudication (IC). However, pain and patient lack of knowledge are key barriers to the uptake of, and adherence to, PA recommendations. This trial will test the efficacy and feasibility of a non-invasive pain management intervention with and without patient education to improve PA in individuals with PAD and IC. Read More

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http://dx.doi.org/10.1186/s13063-019-3307-6DOI Listing
April 2019
1 Read

micro(RNA)-managing muscle wasting.

J Appl Physiol (1985) 2019 Apr 11. Epub 2019 Apr 11.

IACD, University of Liverpool, United Kingdom.

Progressive skeletal muscle wasting is a natural consequence of aging and is common in chronic and acute diseases. Loss of skeletal muscle mass and function (strength) often leads to frailty, decreased independence and increased risk of hospitalization. Despite progress made in our understanding of mechanisms underlying muscle wasting, there is still no treatment available, with exercise training and dietary supplementation improving, but not restoring muscle mass and/or function. Read More

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https://www.physiology.org/doi/10.1152/japplphysiol.00961.20
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http://dx.doi.org/10.1152/japplphysiol.00961.2018DOI Listing
April 2019
2 Reads

Mobility and Participation of People With Disabilities Using Mobility Assistive Technologies: Protocol for a Mixed-Methods Study.

JMIR Res Protoc 2019 Apr 16;8(4):e12089. Epub 2019 Apr 16.

Department of Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, BC, Canada.

Background: Many community-dwelling individuals living with a disability use mobility assistive technologies (MATs). MAT devices are generally beneficial for individuals with mobility impairments. However, less is known about the specific factors that may foster or deter mobility and community participation. Read More

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https://www.researchprotocols.org/2019/4/e12089/
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http://dx.doi.org/10.2196/12089DOI Listing
April 2019
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Anthropometric and Motor Characteristics of South African National Level Female Soccer Players.

J Hum Kinet 2019 Mar 27;66:121-129. Epub 2019 Mar 27.

Centre for Exercise Science and Sports Medicine (CESSM), School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Data regarding anthropometric and motor characteristics of elite national level female soccer players are scarce. Determining these characteristics may likely assist in evaluating the specificity of current training programmes, identify players who might lack specific qualities deemed critical for the successful execution of their tactical roles, and benchmark norms for developing future playing talent. Therefore, the aims of this study were to describe anthropometric and motor characteristics of South African national level female soccer players (n = 37) and determine possible differences with regard to their playing position. Read More

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https://content.sciendo.com/view/journals/hukin/66/1/article
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http://dx.doi.org/10.1515/hukin-2017-0189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458582PMC
March 2019
2 Reads

Aspects of exercise with person-centred guidance influencing the transition to independent exercise: a qualitative interview study among older adults with rheumatoid arthritis.

Eur Rev Aging Phys Act 2019 5;16. Epub 2019 Apr 5.

1Department of Health and Rehabilitation, Unit of Physiotherapy, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Box 455, 405 30 Göteborg, Gothenburg, Sweden.

Background: Besides being health enhancing and disease preventing, exercise is also an important part of the management of chronic conditions, including the inflammatory joint disease rheumatoid arthritis (RA). However, older adults with RA present a lower level of physical activity than healthy older adults. The aim of this qualitative study was to explore aspects of participation in moderate- to high-intensity exercise with person-centred guidance influencing the transition to independent exercise for older adults with RA. Read More

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http://dx.doi.org/10.1186/s11556-019-0211-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449916PMC
April 2019
2 Reads

Exercise training upregulates SIRT1 to attenuate inflammation and metabolic dysfunction in kidney and liver of diabetic mice.

Nutr Metab (Lond) 2019 2;16:22. Epub 2019 Apr 2.

Department of Physical Education, National Taiwan Normal University, 162, Section 1, Heping E. Rd, Taipei City, Taiwan.

Background: Chronic inflammation and metabolic dysregulation may eventually cause tissue damage in obesity-related diseases such as type 2 diabetes. The effects of SIRT1 on integration of metabolism and inflammation may provide a therapeutic target for treatment of obesity-related diseases. We examined the underlying mechanism of moderate intensity aerobic exercise on kidney and liver in obese diabetic mice, mainly focusing on inflammation and metabolic dysfunction. Read More

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http://dx.doi.org/10.1186/s12986-019-0349-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446356PMC
April 2019
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Does exercise impact gut microbiota composition in men receiving androgen deprivation therapy for prostate cancer? A single-blinded, two-armed, randomised controlled trial.

BMJ Open 2019 Apr 14;9(4):e024872. Epub 2019 Apr 14.

Exercise Medicine Research Institute, Edith Cowan University, Perth, Western Australia, Australia.

Introduction: A potential link exists between prostate cancer (PCa) disease and treatment and increased inflammatory levels from gut dysbiosis. This study aims to examine if exercise favourably alters gut microbiota in men receiving androgen deprivation therapy (ADT) for PCa. Specifically, this study will explore whether: (1) exercise improves the composition of gut microbiota and increases the abundance of bacteria associated with health promotion and (2) whether gut health correlates with favourable inflammatory status, bowel function, continence and nausea among patients participating in the exercise intervention. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024872DOI Listing
April 2019
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The trials and tribulations of conducting an m-health pilot randomized controlled trial to improve oral cancer therapy adherence: recommendations for future multisite, non-drug clinical trials.

BMC Res Notes 2019 Apr 15;12(1):226. Epub 2019 Apr 15.

Peter MacCallum Cancer Centre, Parkville, Melbourne, VIC, Australia.

Objective: Integrating mobile phone-based health (m-health) interventions into healthcare systems is one solution to improve access to services for the growing number of patients with chronic illness. Practical challenges such as poor recruitment and inadequate resource allocation can hamper the assessment of such interventions with clinical trial methodology. This paper highlights the challenges encountered during a pilot randomized controlled trial of an m-health medication adherence intervention and offers recommendations for future multi-site, non-drug clinical trials. Read More

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http://dx.doi.org/10.1186/s13104-019-4264-6DOI Listing
April 2019
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Hypertension in obesity: novel insights.

Curr Hypertens Rev 2019 Apr 15. Epub 2019 Apr 15.

3rd Department of Internal Medicine, Hypertension-24h ABPM ESH Center of Excellence, Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki. Greece.

Backround: The relationship between obesity and hypertension has been established in both adults and children. The combination of obesity, hypertension and other cardiovascular risk factors significantly increases the likelihood of adverse cardiovascular effects and raises concerns about aggressive treatment strategies.

Objective: Despite the impressive elements which indicate an important role for excessive weight gain in increasing blood pressure, not all obese patients are hypertensive. Read More

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http://dx.doi.org/10.2174/1573402115666190415154603DOI Listing
April 2019
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Efficacy and safety of dual combination therapy of blood pressure-lowering drugs as initial treatment for hypertension: a systematic review and meta-analysis of randomized controlled trials.

J Hypertens 2019 Apr 9. Epub 2019 Apr 9.

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales.

Objective: To assess the efficacy and tolerability of dual combination of blood pressure (BP)-lowering drugs as initial treatment for hypertension.

Methods: MEDLINE, Embase, CENTRAL were searched until August 2017 for randomized, double-blind trials of dual combination therapy vs. monotherapy in adults with hypertension who were either treatment naïve or untreated for at least 4 weeks. Read More

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http://Insights.ovid.com/crossref?an=00004872-900000000-9722
Publisher Site
http://dx.doi.org/10.1097/HJH.0000000000002096DOI Listing
April 2019
7 Reads