1,154 results match your criteria The Clinical Respiratory Journal [Journal]


The effect of atrial fibrillation intervention on nocturnal respiratory events in elderly patients with persistent AF.

Clin Respir J 2019 Feb 21. Epub 2019 Feb 21.

Cardiology Research Department, Eastbourne General Hospital, UK.

Background: Sleep-disordered breathing (SDB) and atrial fibrillation (AF) are associated. This study investigated the impact of AF intervention on 6 month home sleep testing data.

Methods: Sixty-seven patients (aged 66 to 86, 53% male) with persistent AF were randomized (1:1:1) to direct current cardioversion (DCCV) (22 patients), permanent pacemaker (PPM) + atrioventricular node ablation (AVNA) + DCCV (22 patients) or AF ablation (23 patients). Read More

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http://dx.doi.org/10.1111/crj.13008DOI Listing
February 2019

Most Impactful Predictors for Hyperoxaemia in Exacerbation of Chronic Obstructive Pulmonary Disease Managed by Emergency Medical Services And Emergency Department.

Clin Respir J 2019 Feb 19. Epub 2019 Feb 19.

Emergency Department, Singapore General Hospital.

Introduction: Hyperoxemia in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) leads to adverse outcomes. It remains prevalent in the pre-hospital Emergency Medical Services (EMS) and Emergency Department (ED).

Objective: To determine key predictors for hyperoxemia in AECOPD in EMS and ED. Read More

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http://dx.doi.org/10.1111/crj.13007DOI Listing
February 2019

Higher serum levels of systemic inflammatory markers are linked to greater inspiratory muscle dysfunction in copd.

Clin Respir J 2019 Feb 18. Epub 2019 Feb 18.

Department of Physical Therapy, University of Miami Miller School of Medicine, Coral Gables, FL - United States.

Background: COPD is associated with an inflammatory response that becomes more pronounced in acute exacerbations. Considerable attention has recently focused on the value of several inflammatory mediators in predicting worsening of COPD-related symptoms. Whereas respiratory muscle dysfunction is also widely present in this population, little is known about how systemic inflammation relates to inspiratory muscle dysfunction in COPD. Read More

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http://dx.doi.org/10.1111/crj.13006DOI Listing
February 2019
1 Read

Novel insights in the systemic treatment of lung cancer malignant pleural effusion.

Clin Respir J 2019 Feb 8. Epub 2019 Feb 8.

Department of Pneumonology and Thoracic Oncology, North Hospital, University Hospital of St-Etienne, France.

Lung cancer is the most common fatal malignancy worldwide. Approximately 75% of NSCLC patients are diagnosed at an advanced or a metastatic stage. Since 2007, NSCLC patients with malignant pleural effusion are staged as M1 disease. Read More

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http://dx.doi.org/10.1111/crj.13005DOI Listing
February 2019
1 Read

Performance of new spirometry reference values in preoperative assessment of lung function.

Clin Respir J 2019 Feb 8. Epub 2019 Feb 8.

Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.

Background: Pulmonary function is not routinely assessed in patients without respiratory disease and symptoms before surgery, even if they are smokers. We aimed to check whether the new spirometric reference values of the worldwide Global Lung Initiative (GLI) affected the preoperative assessment of lung function in allegedly lung-healthy patients compared with the still commonly used old predicted values.

Methods: Two hundred nineteen allegedly lung-healthy non-smokers, past and current smokers were examined by spirometry before elective surgery. Read More

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http://dx.doi.org/10.1111/crj.13004DOI Listing
February 2019

Cardiac output measurement during exercise in COPD: A comparison of dye dilution and impedance cardiography.

Clin Respir J 2019 Feb 5. Epub 2019 Feb 5.

1st Department of Critical Care Medicine and Pulmonary Services, GP Livanos and M Simou Laboratories, Medical School of Athens University, Evangelismos Hospital, Athens, Greece.

Introduction: Impedance cardiography (IC) derived from morphological analysis of the thoracic impedance signal is now commonly used for non-invasive assessment of cardiac output (CO) at rest and during exercise. However, in COPD, conflicting findings put its accuracy into question.

Objectives: We therefore compared concurrent CO measurements captured by IC (PhysioFlow : CO ) and by the indocyanine green dye dilution method (CO ) in patients with COPD. Read More

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http://dx.doi.org/10.1111/crj.13002DOI Listing
February 2019
2 Reads

Quantification of critical care medicine: an ICU survey.

Clin Respir J 2019 Feb 5. Epub 2019 Feb 5.

Pulmonary, Critical Care and Sleep Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Background: The shortage in intensivist workforce has been long recognized but no solution has been identified. Meanwhile, while fellowships in Pulmonary and Critical Care Medicine (PCCM) are expanding, other Critical Care Medicine (CCM) programs are contracting. No explanation exists for this contradictory trend, although understanding contributory factors may lead to a solution for the shortage. Read More

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http://dx.doi.org/10.1111/crj.13003DOI Listing
February 2019

The predictive value of plasma osmolality for in-hospital mortality in patients with acute pulmonary embolism.

Clin Respir J 2019 Feb 3. Epub 2019 Feb 3.

Department of Cardiology, Health Sciences University, Sultan Abdülhamid Han Training and Research Hospital, Istanbul, Turkey.

Introduction And Objectives: Prior studies demonstrated that plasma osmolality may have a predictive value for in-hospital mortality in patients with heart failure and acute coronary syndrome. In addition, plasma glucose and blood urea nitrogen (BUN) levels, the components of plasma osmolality, have been shown to be an important contributor for in-hospital mortality in acute pulmonary embolism (APE) patients. Hence, the objective of the current study is to evaluate the effect of plasma osmolality upon admission with in-hospital mortality in patients with APE. Read More

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http://dx.doi.org/10.1111/crj.13001DOI Listing
February 2019
2 Reads

The role of echocardiographic parameters in predicting survival of patients with lung diseases referred for lung transplantation.

Clin Respir J 2019 Jan 31. Epub 2019 Jan 31.

3rd Department of Cardiology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Silesian Centre for Heart Diseasein Zabrze, Poland.

Introduction: Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) show poor prognosis. The importance of left (LV) and right (RV) ventricular morphology and function in patients with end-stage lung diseases referred for lung transplantation (LT) is not well established.

Objectives: To assess whether LV and RV echocardiographic parameters influence survival of patients with IPF, COPD and other interstitial lung diseases (ILD) awaiting LT. Read More

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http://dx.doi.org/10.1111/crj.13000DOI Listing
January 2019
1 Read

The prognostic role of Gender-Age-Physiology system in idiopathic pulmonary fibrosis patients treated with pirfenidone.

Clin Respir J 2019 Jan 23. Epub 2019 Jan 23.

University of Turin, Department of Clinical and Biological Sciences, Interstitial and Rare Lung Disease Unit AOU San Luigi Gonzaga, 10043, Orbassano, Turin, Italy.

Introduction: GAP system have proven to be an easy tool for predicting disease stages and survival in IPF patients.

Objective: To validate mortality risk as determined by the GAP system in a real-life multicenter IPF population treated with pirfenidone.

Methods: The study included patients who received pirfenidone for at least 6 months. Read More

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http://dx.doi.org/10.1111/crj.12999DOI Listing
January 2019
6 Reads

Characteristics of cardiopulmonary exercise testing of patients with borderline mean pulmonary artery pressure.

Clin Respir J 2019 Jan 22. Epub 2019 Jan 22.

Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

Background: Pulmonary hypertension patients with mean pulmonary artery pressure (mPAP) ≥ 25 mm Hg had impaired cardiopulmonary exercise testing (CPET). Borderline mean pulmonary pressures (boPAP; 21-24 mm Hg) represent early pulmonary vasculopathy. The CPET characteristics of boPAP are a matter of discussion. Read More

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http://dx.doi.org/10.1111/crj.12996DOI Listing
January 2019
4 Reads

Disseminated herpes zoster following treatment with benralizumab.

Clin Respir J 2019 Jan 21. Epub 2019 Jan 21.

Department of Internal Medicine, Saint Vincent Hospital, Worcester, Massachusetts.

Background: Disseminated herpes zoster infection occurs mostly in immunocompromised hosts. There have been recent reports of disseminated zoster with chemotherapeutic regimens and newer monoclonal antibodies.

Case Report: The present case describes a 61-year-old patient presenting with disseminated herpes zoster after initiation of benralizumab, an anti-IL-5 monoclonal antibody for severe persistent asthma. Read More

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http://dx.doi.org/10.1111/crj.12998DOI Listing
January 2019
10 Reads
2.197 Impact Factor

Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio as haematological indices of inflammatory response in ceramic workers' silicosis.

Clin Respir J 2019 Jan 21. Epub 2019 Jan 21.

Department of Chest Diseases, Occupational and Environmental Diseases Hospital, Ankara, Turkey.

Introduction: Occupational exposure to crystalline silica over time may result in silicosis: a fatal, irreversible occupational disease leading to lung function impairment. A complex inflammatory process, excessive accumulation of mesenchymal cells and collagen production are the primary mechanisms underlying silicosis. Neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) have emerged as representative indices of systemic inflammation. Read More

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http://dx.doi.org/10.1111/crj.12997DOI Listing
January 2019
5 Reads

Invasive Pulmonary Aspergillosis in Patients with Influenza Infection: A Retrospective Study and Review of the Literature.

Clin Respir J 2019 Jan 20. Epub 2019 Jan 20.

Department of Pulmonary and Critical Care Medicine, Centre for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, P. R. China.

Introduction: There has been a rapid increase in the number of influenza and invasive pulmonary aspergillosis (IPA) co-infection.

Objectives: To explore the risk factors and predictors of a poor prognosis in influenza and IPA co-infection.

Methods: We included patients with confirmed influenza during the 2017 to 2018 influenza season and cases of influenza and IPA co-infection in the literature. Read More

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http://doi.wiley.com/10.1111/crj.12995
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http://dx.doi.org/10.1111/crj.12995DOI Listing
January 2019
7 Reads
2.197 Impact Factor

Temporal trends in survival following ward-based NIV for acute hypercapnic respiratory failure in patients with COPD.

Clin Respir J 2019 Jan 19. Epub 2019 Jan 19.

Respiratory Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.

Introduction: Non-invasive ventilation (NIV) is recommended for treatment of acute hypercapnic respiratory failure (AHRF) in acute exacerbations of COPD. National UK audit data suggests that mortality rates are rising in COPD patients treated with NIV.

Objective: To investigate temporal trends in in-hospital mortality in COPD patients undergoing a first episode of ward-based NIV for AHRF. Read More

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http://doi.wiley.com/10.1111/crj.12994
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http://dx.doi.org/10.1111/crj.12994DOI Listing
January 2019
6 Reads

Comparison of prediction value of four bleeding risk scores for pulmonary embolism with anticoagulation: a real-world study in Chinese patients.

Clin Respir J 2019 Jan 19. Epub 2019 Jan 19.

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Beijing, P. R. China.

Background: Major bleeding (MB) and clinically relevant bleeding (CRB) are the most common seen complications associated with anticoagulation treatment for pulmonary embolism (PE) patients. A bleeding risk score (BRS) may help to accurately determine the risk of bleeding and make better decisions for patients in clinical practice.

Methods: Patients diagnosed as acute PE and met the inclusion criteria in Beijing Chao-Yang Hospital from January 2009 to September 2013 were consecutively enrolled. Read More

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http://dx.doi.org/10.1111/crj.12993DOI Listing
January 2019
4 Reads

The effect of isolated nocturnal oxygen desaturations on serum hs-CRP and IL-6 in patients with chronic obstructive pulmonary disease.

Clin Respir J 2019 Feb;13(2):120-124

Division of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, La Jolla, California.

Introduction: A majority of patients with chronic obstructive pulmonary disease (COPD) die of cardiovascular disease (CVD), yet the mechanisms responsible for this association are not fully understood. It remains unknown if isolated nocturnal oxygen desaturation (iNOD) could be one of the potential pathways by which the 'inflammatory COPD' phenotype leads to CVD.

Objectives: We aimed to evaluate if COPD patients who meet the Medicare guidelines for nocturnal oxygen therapy (iNOT+) had higher serum hs-CRP and IL-6 than those who did not meet the guidelines for iNOT (iNOT-). Read More

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http://doi.wiley.com/10.1111/crj.12992
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http://dx.doi.org/10.1111/crj.12992DOI Listing
February 2019
5 Reads

Serum cardiac troponin elevation predicts mortality in patients with pulmonary hypertension: A meta-analysis of eight cohort studies.

Clin Respir J 2019 Feb;13(2):82-91

The People's Hospital of Yuxi City, The 6th Affiliated Hospital of Kunming Medical University, Yuxi, China.

Objective: To determine the association of serum cardiac troponin (cTn) with the mortality of pulmonary hypertension (PH) patients via a meta-analysis.

Date Source: We searched PubMed and EMBASE from inception to October 25, 2017.

Study Selection: The reference lists of the retrieved articles were also consulted. Read More

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http://dx.doi.org/10.1111/crj.12991DOI Listing
February 2019
2 Reads
2.197 Impact Factor

New insights and improved strategies for the management of primary spontaneous pneumothorax.

Clin Respir J 2019 Jan 7. Epub 2019 Jan 7.

Centre Valaisan de Pneumologie, Department of Internal Medicine, Montana, Switzerland.

The pathophysiology and management of primary spontaneous pneumothorax (PSP) are subject of debate. Despite advances in the understanding of its etiopathogenesis and improvements in its management, implementation in clinical practice is suboptimal. In this manuscript, we review the recent literature with a focus on PSP pathophysiology and management. Read More

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http://dx.doi.org/10.1111/crj.12990DOI Listing
January 2019
3 Reads

Lung hypoperfusion in children with complicated pneumonia may be assessed by Doppler ultrasound of the main pulmonary arteries.

Clin Respir J 2019 Feb;13(2):125-128

Pediatric Allergy and Respiratory Unit, Alicante University General Hospital, Alicante, Spain.

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http://dx.doi.org/10.1111/crj.12989DOI Listing
February 2019
2 Reads

Identification of genomic copy number variations in lung benign metastasizing leiomyomatosis.

Clin Respir J 2019 Feb 29;13(2):105-113. Epub 2019 Jan 29.

Servicio de Neumología, Unidad Médica de Alta Especialidad, Hospital de Especialidades del Centro Médico Nacional, Siglo XXI, IMSS, Ciudad de México, México.

Objectives: Lung metastasizing leiomyomatosis (LML) is an infrequently diagnosed pathology developed after sexual maturation, commonly preceded by uterine myomas. Symptoms can include difficulties to breathe, cough, dyspnea and pain, because of mechanical obstruction exerted by expanding local growing leiomyomas. Lung leiomyomas are normally detected by imaging studies, but nowadays the precise diagnosis demands histological characterization of biopsies obtained from the affected tissues. Read More

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http://doi.wiley.com/10.1111/crj.12987
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http://dx.doi.org/10.1111/crj.12987DOI Listing
February 2019
3 Reads

Comparison of two lung cancer screening scores among patients with chronic obstructive pulmonary disease: A community study.

Clin Respir J 2019 Feb;13(2):114-119

Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

Introduction: Based on the National Lung Cancer Screening Trial (NLST), guidelines on screening programs for lung cancer have recommended low-dose computed tomography (LDCT). De Torres et al made a score for COPD patients (COPD-LUCSS) to improve their selection criteria.

Objective: To examine and compare the discriminating value of both scores in a community-based cohort of COPD patients. Read More

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http://dx.doi.org/10.1111/crj.12988DOI Listing
February 2019
1 Read

Small cell lung cancer in the young: Characteristics, diagnosis and outcome data.

Clin Respir J 2019 Feb 28;13(2):98-104. Epub 2019 Jan 28.

Department of Medical Oncology, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Background: Patients with small cell lung cancer (SCLC) younger than 40 years are limited in number. Our research aimed to assess the characteristics, diagnosis and outcomes of this patient population.

Methods: Records of patients under the age of 40 with SCLC at the Chinese Academy of Medical Sciences between January 2006 and December 2015 were reviewed and evaluated. Read More

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http://dx.doi.org/10.1111/crj.12986DOI Listing
February 2019
2 Reads

Adequacy of EBUS-TBNA specimen for mutation analysis of lung cancer.

Clin Respir J 2019 Feb;13(2):92-97

Gazi University Medical Faculty, Department of Pathology, Ankara, Turkey.

Objective: Convex probe endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is a minimally invasive technique with high sensitivity in the mediastinal staging of non-small cell carcinoma (NSCLC). In recent years, molecular testing has been developed to study genetic mutations in NSCLC. There are studies revealing improved survival in advanced NSCLC using targeted therapy as the first-line treatment in these patients. Read More

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http://dx.doi.org/10.1111/crj.12985DOI Listing
February 2019
2 Reads
2.197 Impact Factor

Subglottic perioperative airway-tube inflation via randomized evaluation with variable syringe size (Spair-Tire) study.

Clin Respir J 2019 Jan;13(1):66-69

Department of Anesthesiology, The University of Texas Health Science Center at Houston (UTHealth), McGovern Medical School, Houston, Texas.

Introduction: Risks of endotracheal tube cuff (ETTC) over inflation must be balanced with the need to achieve a minimum pressure of 20 cm H O. Methods have been developed to estimate adequate ETTC pressurization but do not provide accurate endotracheal tube cuff pressure (ETCP) measurements. Hence, different sized syringes may play a role in determining ETCP. Read More

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http://dx.doi.org/10.1111/crj.12984DOI Listing
January 2019
2 Reads

Is there any role for thoracoscopy in the diagnosis of benign pleural effusions.

Clin Respir J 2019 Feb;13(2):73-81

Department of Respiratory Medicine, University Hospital of Evros, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

Thoracoscopy in the endoscopy suite, has a high diagnostic yield of undiagnosed pleural effusions with minimal and mild complications. Whereas relatively minimal invasive techniques, such as thoracentesis, image-guided pleural biopsy or blind pleural biopsy, can yield sufficient cell or tissue material to establish the diagnosis of the underlying condition, more definite invasive diagnostic and therapeutic procedure, such as thoracoscopy, may be required for accurate sampling and diagnosis, and further provide real-time treatment options in same procedure. If thoracoscopy is considered the gold standard for the diagnosis is a fact in case. Read More

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http://doi.wiley.com/10.1111/crj.12983
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http://dx.doi.org/10.1111/crj.12983DOI Listing
February 2019
7 Reads

Pleura revisited: From histology and pathophysiology to pathology and molecular biology.

Clin Respir J 2019 Jan;13(1):3-13

Department of Pathology, North Hospital, University Hospital of St-Etienne, St-Etienne, France.

Pleural cavity has an interesting physiology that when impaired gives rise to pleural effusions a rather frequent problem in respiratory medicine practice. Their aetiology varies widely producing distinct pathological lesions with different prognosis and treatment. The basic morphological features of pleural diseases, neoplastic and non-neoplastic, will be analysed in this review with an emphasis to their pathophysiology, differential diagnosis and clinicopathological correlations. Read More

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http://dx.doi.org/10.1111/crj.12982DOI Listing
January 2019
1 Read

Could SUVmax be an auxiliary parameter in the clinical management of pulmonary hydatid disease?

Clin Respir J 2019 Jan;13(1):58-65

Department of Pathology, Ataturk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey.

Objective: The aim of this study was to investigate the role of 18F-fluorodeoxyglucose positron emission tomography/computerized tomography (FDG-PET/CT) in the diagnosis and treatment of pulmonary hydatid disease and also compare the morphological characteristics of the lesions with SUVmax values and identify complicated disease.

Methods: Thirty-six patients with a diagnosis of pulmonary hydatid disease who underwent 18F-FDG PET/CT imaging were included in this retrospective study. The size of the lesions, morphological characteristics, accompanying parenchymal and pleural findings, SUVmax and HUmean values and FDG uptake in mediastinal lymph nodes were noted. Read More

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http://doi.wiley.com/10.1111/crj.12981
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http://dx.doi.org/10.1111/crj.12981DOI Listing
January 2019
8 Reads

Bibliometric analysis of scientific publications in respiratory journals from China and other top-ranking countries between 2007 and 2017.

Clin Respir J 2019 Jan;13(1):50-57

Department of Respiratory and Critical Care Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

Introduction: Respiratory disease remains one of the leading causes of mortality and morbidity worldwide.

Objectives: In this study, we aimed to compare the quantity and quality of scientific publications in the field of respirology from the United States, the United Kingdom, Germany, Canada and China.

Methods: Articles published in 58 respiratory journals from 2007 to 2017 were screened with Science Citation Index Expanded database. Read More

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http://dx.doi.org/10.1111/crj.12980DOI Listing
January 2019
1 Read
2.197 Impact Factor

Hidden morbidity: The results of a collaborative community chronic obstructive pulmonary disease screening initiative.

Clin Respir J 2019 Jan;13(1):43-49

Respiratory Medicine, Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom.

Chronic obstructive pulmonary disease (COPD) often goes unrecognised resulting in people living with the disease without a diagnosis. We investigated the characteristics, symptom burden and flow of participants in a community COPD screening initiative. Screening was undertaken during four events over 2-weeks. Read More

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http://dx.doi.org/10.1111/crj.12978DOI Listing
January 2019
2 Reads
2.197 Impact Factor

Implementation of a depression screening protocol among respiratory insufficiency patients.

Clin Respir J 2019 Jan;13(1):34-42

Faculty of Medicine and Life Sciences, The Gerontology Research Centre (GEREC), University of Tampere, Tampere, Finland.

Introduction: Unnoticed and untreated depression is prevalent among patients with chronic respiratory insufficiency. Comorbid depression causes suffering and worsens patients' outcomes.

Objectives: The objective of this evaluation was to assess preliminary outcomes of a depression screening protocol among chronic respiratory insufficiency patients at a tertiary care pulmonary outpatient clinic. Read More

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http://dx.doi.org/10.1111/crj.12977DOI Listing
January 2019
2 Reads

CD146-mediated acquisition of stemness phenotype enhances tumour invasion and metastasis after EGFR-TKI resistance in lung cancer.

Clin Respir J 2019 Jan;13(1):23-33

Department of Respiratory Medicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China.

Introduction: Tumours are more likely to metastasize after the development of resistance to EGFR-TKIs. CD146 is a multifunctional molecule and is implicated in tumour invasion and metastasis; however, its role in lung cancer has not been clearly established.

Objective: Here, we aimed to explore the relationship between CD146 pathway and stem cell phenotype after EGFR-TKI resistance in lung cancer. Read More

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http://dx.doi.org/10.1111/crj.12976DOI Listing
January 2019
2 Reads
2.197 Impact Factor

Paediatric asthma prevalence: The first national population-based survey in Iran.

Clin Respir J 2019 Jan 11;13(1):14-22. Epub 2019 Jan 11.

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: The actual prevalence of paediatric asthma as a worldwide chronic disease has been surveyed in developed countries. However, no sufficient survey has been conducted in most of the eastern developing countries. Herein, we took measures to evaluate the prevalence of paediatric asthma in Iran. Read More

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http://dx.doi.org/10.1111/crj.12975DOI Listing
January 2019
3 Reads

Assessment of lateral mitral, septal and tricuspid myocardial performance indices by tissue Doppler imaging in asthmatic children.

Clin Respir J 2018 Dec;12(12):2676-2682

Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Introduction: Recurrent hypoxia makes asthmatics at risk for pulmonary hypertension and ventricular dysfunction. Early stages of these cardiovascular diseases cannot be detected by conventional echocardiography. Tissue Doppler imaging has been introduced recently as a more sensitive and more accurate tool for investigating cardiovascular diseases. Read More

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http://doi.wiley.com/10.1111/crj.12974
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http://dx.doi.org/10.1111/crj.12974DOI Listing
December 2018
10 Reads

Comparing severity scores in exacerbations of chronic obstructive pulmonary disease.

Clin Respir J 2018 Dec;12(12):2668-2675

Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand.

Introduction: Prognostic scores help identify patients at a high risk of mortality in exacerbations of chronic obstructive pulmonary disease (COPD). The Dyspnoea, Eosinopaenia, Consolidation, Acidaemia and atrial Fibrillation (DECAF) score has been reported to perform better than other severity scores in predicting mortality from exacerbations of COPD in studies including patients with pneumonia.

Objective: To compare the performance of DECAF with other prognostic scores: CURB-65, CRB-65 and BAP-65, in predicting 30-day mortality in patients hospitalised with exacerbations of COPD without pneumonia. Read More

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http://dx.doi.org/10.1111/crj.12973DOI Listing
December 2018
1 Read

Outbreak of mycoplasmal round pneumonia in an adult population: A case series.

Clin Respir J 2018 Dec;12(12):2659-2667

Department of Respiratory and Critical Care Medicine, Fuzhou General Hospital of the PLA, Fuzhou General Hospital of Fujian Medical University, Dongfang Hospital of Xiamen University, Fuzhou, China.

Background: Mycoplasmal pneumonia is a common type of adult community-acquired pneumonia in China, but round/spherical pneumonia caused by mycoplasma pneumoniae has rarely been reported. Here, we report an outbreak of mycoplasmal round pneumonia in a military dormitory in China.

Methods: We analysed epidemiological, clinical, imaging and laboratory data from a series of adults affected by an outbreak of mycoplasmal round pneumonia in the dormitory of a military hospital (Fuzhou General Hospital) in Fuzhou, China. Read More

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http://doi.wiley.com/10.1111/crj.12972
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http://dx.doi.org/10.1111/crj.12972DOI Listing
December 2018
17 Reads

A new perspective for pulmonary thromboembolism radiology: 'Pulmonary vein sign'.

Clin Respir J 2018 Dec 13;12(12):2653-2658. Epub 2018 Nov 13.

Department of Chest Diseases, Dr Suat Seren Chest Diseases and Surgery Training and Research Hospital, University of Health Sciences, Izmir, Turkey.

Introduction: Pulmonary thromboembolism (PTE) is a clinical condition that can result in sudden death. Computed tomography pulmonary angiography (CTPA) is the most sensitive imaging technique for the diagnosis of PTE. Filling defects in the pulmonary veins, which can be identified in areas adjacent to PTE, have been named the 'pulmonary vein sign' (PVS). Read More

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http://dx.doi.org/10.1111/crj.12971DOI Listing
December 2018
1 Read

Metformin synergistically enhances the antitumor activity of the third-generation EGFR-TKI CO-1686 in lung cancer cells through suppressing NF-κB signaling.

Clin Respir J 2018 Dec 9;12(12):2642-2652. Epub 2018 Nov 9.

Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.

Purpose: Third-generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), rociletinib (CO-1686), is great efficacy against EGFR-mutated patients bearing the T790M resistance mutation. However, acquired resistance may emerge. There is a need to characterize acquired resistance mechanism(s) and to devise ways to overcome CO-1686 resistance. Read More

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http://doi.wiley.com/10.1111/crj.12970
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http://dx.doi.org/10.1111/crj.12970DOI Listing
December 2018
3 Reads
2.200 Impact Factor

Right heart failure as a risk factor for severe exacerbation in patients with chronic obstructive pulmonary disease: Prospective cohort study.

Clin Respir J 2018 Dec 11;12(12):2635-2641. Epub 2018 Nov 11.

Heart Failure and Respiratory Distress Clinic, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Mexico City, Mexico.

Background: The prognosis in patients with Chronic Obstructive Pulmonary Disease (COPD) depends, in large part, on the frequency of exacerbations. Cardiovascular diseases, including heart failure (HF), are the risk factors for exacerbations. However, the importance of HF type over the exacerbations in COPD patients is unknown. Read More

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http://dx.doi.org/10.1111/crj.12969DOI Listing
December 2018
4 Reads

Use of beta-blocker is associated with lower mortality in patients with coronary artery disease with or without COPD.

Clin Respir J 2018 Dec 4;12(12):2627-2634. Epub 2018 Nov 4.

Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.

Introduction: Beta-blockers are indicated for secondary prevention of coronary artery disease (CAD). However, in patients with co-morbidity of chronic obstructive pulmonary disease (COPD) an underuse of beta-blocker has been reported.

Materials And Methods: Prescription and demographic data and information on hospital discharge diagnoses from 13 Austrian health insurance funds for the years 2006-2007 were analyzed. Read More

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http://doi.wiley.com/10.1111/crj.12968
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http://dx.doi.org/10.1111/crj.12968DOI Listing
December 2018
11 Reads

Living in the city centre is associated with type 1 sensitization to outdoor allergens in Leipzig, Germany.

Clin Respir J 2018 Dec 25;12(12):2686-2688. Epub 2018 Oct 25.

Department of Dermatology, Venerology and Allergology, UMC Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1111/crj.12967DOI Listing
December 2018
9 Reads

Chest physiotherapy with early mobilization may improve extubation outcome in critically ill patients in the intensive care units.

Clin Respir J 2018 Nov 25;12(11):2613-2621. Epub 2018 Oct 25.

School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: Extubation failure can lead to a longer intensive care unit (ICU) stay, higher mortality rate, and higher risk of requiring tracheostomy. Chest physiotherapy (CPT) can help patients in reducing the accumulation of airway secretion, preventing collapsed lung, improving lung compliance, and reducing comorbidities. Much research has investigated the correlation between CPT and respiratory system clearance. Read More

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http://dx.doi.org/10.1111/crj.12965DOI Listing
November 2018
3 Reads

Use of online symptom checkers to delineate the ever-elusive GERD versus non-GERD cough.

Clin Respir J 2018 Dec 4;12(12):2683-2685. Epub 2018 Nov 4.

Department of Medicine, Ascension Wheaton Franciscan Healthcare, Milwaukee, Wisconsin.

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http://dx.doi.org/10.1111/crj.12966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309931PMC
December 2018
3 Reads

Chronic obstructive pulmonary disease mortality, a competing risk analysis.

Clin Respir J 2018 Nov 25;12(11):2598-2605. Epub 2018 Oct 25.

Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico.

Background: Current risk factors for Chronic Obstructive Pulmonary Disease mortality focus only on overall and respiratory death. We investigated whether risk factors for each specific cause of mortality are different depending on the outcome under consideration.

Methods: This retrospective cohort study included patients with a clinical diagnosis of COPD, older than 40, greater than 20 pack-years smoking history, and obstructive pattern on spirometry. Read More

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http://dx.doi.org/10.1111/crj.12963DOI Listing
November 2018
13 Reads

A simple test to assess the emotional status of smokers.

Clin Respir J 2018 Nov;12(11):2606-2612

Internal Medicine Department, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.

Background And Aims: Smokers exhibit a high prevalence of psychological abnormalities, and these factors may contribute to smoking initiation, its maintenance, and quitting difficulties. This study reports the development of a scale aiming at evaluating the emotional status of smokers in face of tobacco.

Methods: Levels of Anxiety, Depression, Perceived Stress, Self-esteem, and Loneliness of 120 smokers (age: 54. Read More

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http://dx.doi.org/10.1111/crj.12964DOI Listing
November 2018
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Recent developments in pleurodesis for malignant pleural disease.

Clin Respir J 2018 Oct;12(10):2463-2468

Department of Thoracic Oncology, Pleural Diseases and Interventional Pulmonology, Hôpital Nord, Marseille, France.

Objective: Metastatic pleural effusion (MPE) is one of the most frequent causes of pleural effusion. The aims of the therapeutic management are palliation of symptoms and improvement in patient's quality of life. The first step is a therapeutic thoracentesis. Read More

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http://dx.doi.org/10.1111/crj.12958DOI Listing
October 2018
21 Reads

Diabetes and tuberculosis: A closer and closer relationship.

Clin Respir J 2018 Nov 24;12(11):2622-2623. Epub 2018 Oct 24.

Department of Translational Medicine, Pneumology Unit U, Università del Piemonte Orientale, PO Sant'Andrea, Vercelli, Italy.

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http://dx.doi.org/10.1111/crj.12962DOI Listing
November 2018
2 Reads

The association between Cytomegalovirus co-infection with Pneumocystis pneumonia and mortality in immunocompromised non-HIV patients.

Clin Respir J 2018 Nov;12(11):2590-2597

Department of Medical Microbiology, Ege University Medical School, Izmir, Turkey.

Introduction: Impact of Cytomegalovirus (CMV) co-infection pneumonia in non-HIV patients with Pneumocystis jirovecii pneumonia (PCP) is unclear.

Objectives: The aim of our study was to determine whether CMV co-infection is associated with an increased risk of mortality.

Methods: Our study was conducted at Ege University Hospital, Turkey. Read More

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http://dx.doi.org/10.1111/crj.12961DOI Listing
November 2018
5 Reads

First assessment of interferon gamma release assay results among healthcare workers at a general hospital in China.

Clin Respir J 2018 Nov 25;12(11):2581-2589. Epub 2018 Oct 25.

Nosocomial Infection Control Office of China-Japan Friendship Hospital, Beijing, China.

Introduction: China has a very high tuberculosis (TB) burden. The interferon-gamma release assay (IGRA) is more specific for the diagnosis of latent tuberculosis infection (LTBI) than the tuberculin skin test, especially among populations with a high degree of coverage by the BCG vaccine.

Objectives: To evaluate the first screening of healthcare workers (HCW) for LTBI using the IGRA at a general hospital in Beijing. Read More

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http://dx.doi.org/10.1111/crj.12960DOI Listing
November 2018
3 Reads

Evaluation of multidisciplinary pulmonary rehabilitation education delivered by either DVD or spoken talk.

Clin Respir J 2018 Nov 25;12(11):2546-2550. Epub 2018 Sep 25.

Respiratory Medicine, Leicester Hospital, Leicester, United Kingdom.

Introduction: Pulmonary rehabilitation (PR) is a multidisciplinary program of care for patients with chronic respiratory disease. The educational component is an integral component and represents a large proportion of a program. However, it can be difficult to secure regular multidisciplinary input to PR programs. Read More

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http://doi.wiley.com/10.1111/crj.12954
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http://dx.doi.org/10.1111/crj.12954DOI Listing
November 2018
6 Reads