4,419 results match your criteria The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques[Journal]


Vitamins and Minerals for Migraine Prophylaxis: A Systematic Review and Meta-analysis.

Can J Neurol Sci 2019 Feb 15:1-10. Epub 2019 Feb 15.

George & Fay Yee Centre for Healthcare Innovation, Max Rady College of Medicine, Rady Faculty of Health Sciences,University of Manitoba,Winnipeg,Canada.

Objective: To summarize the findings of randomized controlled trials (RCTs) on the efficacy and safety of vitamins and minerals for migraine prophylaxis.

Methods: We systematically searched bibliographic databases and relevant websites for parallel and crossover RCTs reporting efficacy and/or safety of vitamins and/or minerals for migraine prophylaxis. Our primary outcomes were migraine frequency (number of attacks) and duration (hours). Read More

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http://dx.doi.org/10.1017/cjn.2018.394DOI Listing
February 2019

Nociceptive Primitive Reflexes in Neurologically and Cognitively Healthy Aging Subjects.

Can J Neurol Sci 2019 Feb 14:1-10. Epub 2019 Feb 14.

From the Department of Experimental Biomedicine and Clinical Neurosciences,University of Palermo,Palermo,Italy.

Background: To assess the prevalence of three nociceptive primitive reflexes (nPR), i.e., glabellar tap, snout reflex, and palmomental reflex, in neurologically and cognitively healthy (NCH) aging subjects. Read More

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February 2019
2 Reads

Muscular Ultrasound, Syndecan-1 and Procalcitonin Serum Levels to Assess Intensive Care Unit-Acquired Weakness.

Can J Neurol Sci 2019 Feb 11:1-9. Epub 2019 Feb 11.

Department of Anaesthesiology and Intensive Care Medicine,University Medical,Center Rostock, Rostock,Germany.

Background: Intensive care unit-acquired weakness (ICU-AW) is associated with poorer outcome of critically ill patients. Microcirculatory changes and altered vascular permeability of skeletal muscles might contribute to the pathogenesis of ICU-AW. Muscular ultrasound (MUS) displays increased muscle echogenicity, although its pathogenesis is uncertain. Read More

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http://dx.doi.org/10.1017/cjn.2018.390DOI Listing
February 2019
1 Read

Discharge Destination from a Rehabilitation Unit After Acute Ischemic Stroke.

Can J Neurol Sci 2019 Feb 11:1-7. Epub 2019 Feb 11.

Grey Bruce Health Services,Owen Sound, Ontario,Canada.

Background: We reviewed numerous variables for ischemic stroke patients admitted to a rehabilitation unit to determine those that were statistically associated with discharge destination.

Methods: A retrospective chart review of patients with ischemic stroke discharged from the rehabilitation unit between January 1, 2005 and December 31, 2015. Variables were examined for their association with discharge destination (home versus long-term care (LTC)). Read More

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http://dx.doi.org/10.1017/cjn.2018.386DOI Listing
February 2019
1 Read

Clinical Features of Lewis-Sumner Syndrome: Can Trauma Precipitate Symptoms?

Can J Neurol Sci 2019 Feb 6:1-5. Epub 2019 Feb 6.

Department of Neurology,Memorial University of Newfoundland,St. John's, Newfoundland,Canada.

Introduction: Lewis-Sumner syndrome (LSS) is a demyelinating peripheral neuropathy described in 1982.

Methods: We reviewed the charts of nine LSS patients in neurological care for their symptoms, response to different treatment regimens, and pattern of nerve involvement.

Results: One patient had an Adie's pupil. Read More

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http://dx.doi.org/10.1017/cjn.2018.389DOI Listing
February 2019
1 Read

Is the Hypointensity in Motor Cortex the Hallmark of Amyotrophic Lateral Sclerosis?

Can J Neurol Sci 2019 Feb 6:1-8. Epub 2019 Feb 6.

Laboratory of Clinical Investigation,Instituto Nacional de Neurología y Neurocirugía MVS,Mexico City,Mexico.

Background: Amyotrophic lateral sclerosis (ALS) is a devastating disease that targets motor neurons. Upper motor neurons degeneration is pathologically characterized by brain iron accumulation. Signal attenuation in the shape of a ribbon at the posterior border of the precentral gyrus can be observed on conventional magnetic resonance imaging (MRI) sequences including T2-weighted sequence. Read More

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http://dx.doi.org/10.1017/cjn.2018.382DOI Listing
February 2019
3 Reads

How Much Sciatic Nerve Does Hip Flexion Require?

Can J Neurol Sci 2019 Jan 30:1-3. Epub 2019 Jan 30.

Department of Medical Imaging, Sunnybrook Health Sciences Centre,University of Toronto,Toronto, Ontario,Canada.

Measured nerve conduction velocity in the fibular nerve increases across the knee during hip flexion. This is due to stretching of sciatic and fibular nerves. We modeled the additional nerve length required for the sciatic nerve to course around the flexed hip, based upon distance between the hip and the sciatic nerve on magnetic resonance imaging (MRI). Read More

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January 2019

Through the Skin, To the Nerves: Subcutaneous Immunoglobulin for Neuromuscular Diseases.

Authors:
Hans D Katzberg

Can J Neurol Sci 2019 Jan;46(1):1-2

Division of Neurology,University Health Network/University of

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http://dx.doi.org/10.1017/cjn.2018.383DOI Listing
January 2019
1 Read

Reply to Richard Leblanc's Letter to the Editor, "Cerebrovascular Neurosurgery in Canada: An Historical Review".

Authors:
Suresh Ramnath

Can J Neurol Sci 2019 Jan;46(1):123

Department of NeurosurgeryUniversity of Michigan,Ann ArborMI,USA.

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January 2019

Utilization of Spinal Intra-operative Three-dimensional Navigation by Canadian Surgeons and Trainees: A Population-based Time Trend Study.

Can J Neurol Sci 2019 Jan;46(1):87-95

1Division of Neurosurgery,Department of Surgery,University of Toronto,Toronto,Ontario,Canada.

Background: Computer-assisted navigation (CAN) improves the accuracy of spinal instrumentation in vertebral fractures and degenerative spine disease; however, it is not widely adopted because of lack of training, high capital costs, workflow hindrances, and accuracy concerns. We characterize shifts in the use of spinal CAN over time and across disciplines in a single-payer health system, and assess the impact of intra-operative CAN on trainee proficiency across Canada.

Methods: A prospectively maintained Ontario database of patients undergoing spinal instrumentation from 2005 to 2014 was reviewed retrospectively. Read More

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http://dx.doi.org/10.1017/cjn.2018.376DOI Listing
January 2019

An Acute Clinical Presentation Associated with Hypertrophic Olivary Degeneration.

Can J Neurol Sci 2019 Jan;46(1):137-139

Department of Clinical Neurosciences Cumming School of MedicineUniversity of Calgary,Calgary Alberta,Canada.

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January 2019
2 Reads

Ischemic Stroke in a Transgender Woman Receiving Estrogen Therapy.

Can J Neurol Sci 2019 Jan;46(1):145-146

2Department of Neurology,University of TorontoToronto,Canada.

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January 2019

Emergency Embolization of Artery of Adamkiewicz Pseudoaneurysm Following Methylenedioxymethamphetamine Abuse.

Can J Neurol Sci 2019 Jan;46(1):140-144

2Division of NeurosurgeryVancouver General Hospital,VancouverBC,Canada.

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January 2019
5 Reads

Applying Behavioral Economics and Neuroeconomics to Medical Education and Clinical Care.

Authors:
Gustavo Saposnik

Can J Neurol Sci 2019 Jan;46(1):35-37

1Department of Economics,University of Zurich.

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January 2019
5 Reads

Deep Brain Stimulation as a Rescue When Duodenal Levodopa Infusion Fails.

Can J Neurol Sci 2019 Jan;46(1):130-131

1Deparment of Medicine (Neurology),University of AlbertaEdmonton, Alberta,Canada.

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http://dx.doi.org/10.1017/cjn.2018.366DOI Listing
January 2019

Evaluation of a Personalized Subcutaneous Immunoglobulin Treatment Program for Neurological Patients.

Can J Neurol Sci 2019 Jan;46(1):38-43

2Division of Infectious Diseases, Department of Medicine,The Ottawa Hospital,Ottawa, Ontario,Canada.

Background: Subcutaneous immunoglobulin (SCIg) treatment has been shown to control symptoms and improve overall satisfaction in patients with neurological disorders. However, a large injection volume can be overwhelming and a barrier to successful SCIg treatment. We established a nurse-led individualized approach program to facilitate a smooth and successful treatment transition from intravenous immunoglobulin (IVIg) to SCIg. Read More

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http://dx.doi.org/10.1017/cjn.2018.363DOI Listing
January 2019
2 Reads

Persistent Headache Attributed to Traumatic Injury to the Head: Can We Do Better?

Authors:
Werner J Becker

Can J Neurol Sci 2019 Jan;46(1):3-4

Department of Clinical Neurosciences,University of Calgary,Calgary,AB,Canada(WJB).

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http://dx.doi.org/10.1017/cjn.2018.359DOI Listing
January 2019

Looking Glass Syndromes: Two Sides of the Same Gene.

Can J Neurol Sci 2019 Jan;46(1):115-120

1Department of Clinical Neurological Sciences,Schulich School of Medicine and Dentistry,Western University,London,Canada.

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http://dx.doi.org/10.1017/cjn.2018.354DOI Listing
January 2019
1 Read

Nutrients in Alzheimer's Disease: The Interaction of Diet, Drugs and Disease.

Can J Neurol Sci 2019 Jan;46(1):23-34

1Krembil Research Institute,University Health Network,Toronto,ON,Canada.

In recent decades, clinical trials in Alzheimer's disease (AD) have failed at an unprecedented rate. The etiology of AD has since come under renewed scrutiny, both to elucidate the underlying pathologies and to identify novel therapeutic strategies. Here, diet has emerged as a potential causative/protective agent. Read More

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http://dx.doi.org/10.1017/cjn.2018.353DOI Listing
January 2019

Adherence to Guidelines at a Stroke Prevention Clinic: A Follow-up Study.

Can J Neurol Sci 2019 Jan;46(1):57-63

1Faculty of Medicine,McGill University,Montreal,Quebec,Canada.

Background: In 2010, we published our stroke prevention clinic's performance as compared to Canadian stroke prevention guidelines. We now compare our clinic's adherence with guidelines to our previous results, following the implementation of an electronic documentation form.

Methods: All new patients referred to our clinic (McGill University Health Center) for recent transient ischemic attack (TIA) or ischemic stroke between 2014 and 2017 were included. Read More

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January 2019
4 Reads

Geographic Disparities in the Surgical Management of Hemifacial Spasm in Canada.

Can J Neurol Sci 2019 Jan;46(1):83-86

1Section of Neurosurgery,University of Manitoba,Winnipeg, Manitoba,Canada(MS, AMK).

Background: We aimed to interrogate the Canadian Institute for Health Information (CIHI) database in order to determine the geographic distribution and outcomes of microvascular decompression (MVD) for the treatment of hemifacial spasm (HFS).

Methods: The CIHI database was searched from 2004 to 2017 for relevant diagnostic and procedure codes. A new database was populated with the following categories: year, institution, province, number of interventions per year, and mean length of stay. Read More

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http://dx.doi.org/10.1017/cjn.2018.350DOI Listing
January 2019

Time Trends of the Incidence, Prevalence, and Mortality of Parkinsonism.

Can J Neurol Sci 2019 Jan 28:1-8. Epub 2019 Jan 28.

Public Health Ontario,Toronto, Ontario,Canada.

Objectives: We assessed trends in the incidence, prevalence, and post-diagnosis mortality of parkinsonism in Ontario, Canada over 18 years. We also explored the influence of a range of risk factors for brain health on the trend of incident parkinsonism.

Methods: We established an open cohort by linking population-based health administrative databases from 1996 to 2014 in Ontario. Read More

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http://dx.doi.org/10.1017/cjn.2018.387DOI Listing
January 2019

Phenotypic Variability of Essential Tremor Based on the Age at Onset.

Can J Neurol Sci 2019 Jan 28:1-7. Epub 2019 Jan 28.

Department of Neurology,National Institute of Mental Health and Neurosciences,Bangalore,India.

Background: Essential tremor (ET) is reported to have a bimodal distribution of age at onset (AAO) with phenotypic variability based on the AAO. This study aims to explore the distribution of AAO based on mathematical modeling and ascertain the differences, if any, in the clinical features of groups.

Methods: A chart review was conducted for 252 patients with ET diagnosed based on the Consensus statement of the Movement Disorder Society on Tremor. Read More

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http://dx.doi.org/10.1017/cjn.2018.384DOI Listing
January 2019
1.599 Impact Factor

Recurrent Herpes Simplex Virus Encephalitis After Epilepsy Surgery.

Can J Neurol Sci 2019 Jan 22:1-3. Epub 2019 Jan 22.

Department of Clinical Neurosciences,University of Calgary,Calgary,Canada.

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http://dx.doi.org/10.1017/cjn.2018.385DOI Listing
January 2019
1 Read
1.599 Impact Factor

Application of Automated Brain Segmentation and Fiber Tracking in Hemimegalencephaly.

Can J Neurol Sci 2019 Jan 22:1-3. Epub 2019 Jan 22.

Division of Neuroradiology, Geneva University Hospital and Faculty of Medicine of Geneva,Geneva,Switzerland.

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http://dx.doi.org/10.1017/cjn.2018.381DOI Listing
January 2019
1 Read

Clinical Utility of Longitudinal Measurement of Motor Threshold in Wilson's Disease.

Can J Neurol Sci 2019 Jan 22:1-4. Epub 2019 Jan 22.

Department of Neurology,National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore,India.

This study describes the longitudinal changes of resting motor threshold (RMT) and central motor conduction time (CMCT) in 18 patients with Wilson's disease (WD). The RMT, CMCT, and Global Assessment Scale for Wilson Disease (GAS-WD) were measured at baseline and at follow-up after 12.94 ± 7. Read More

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January 2019
1 Read
1.599 Impact Factor

Magnetoencephalographic Source Localization of the Eye Area of the Motor Homunculus.

Can J Neurol Sci 2018 Dec 17:1-7. Epub 2018 Dec 17.

1Division of Neurology,Krembil Brain Institute,University Health Network, Toronto Western Hospital,University of Toronto,Toronto, Ontario,Canada.

A patient with intractable epilepsy, previous right frontal resection, and active vagus nerve stimulation (VNS) developed new onset quasi-continuous twitching around the left eye. Electroencephalography showed no correlate to the orbicularis oculi twitches apart from myographic potentials at the left supraorbital and anterior frontal electrodes. Magnetoencephalography was performed using spatiotemporal signal space separation to suppress magnetic artifacts associated with the VNS apparatus. Read More

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December 2018
2 Reads

A Case of a Cardiac Cephalgia.

Can J Neurol Sci 2019 Jan 6;46(1):124-126. Epub 2018 Dec 6.

Department of Clinical Neurosciences Cumming School of MedicineUniversity of Calgary,Calgary Alberta,Canada.

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January 2019
2 Reads

Links Between Strokes and Hereditary Hemorrhagic Telangiectasia: A Population-Based Study.

Can J Neurol Sci 2019 Jan 6;46(1):44-50. Epub 2018 Dec 6.

Department of Medicine, Division of Pulmonary,University of Alberta,Edmonton, Alberta,Canada.

Background: Hereditary hemorrhagic telangiectasia (HHT) is a disease of abnormal vasculature where patients are predisposed to strokes of multiple etiologies. We assessed yearly stroke incidence among Albertans with HHT and compared with the general population. Given the tendency for stroke in HHT patients, we expected HHT patients to have higher stroke incidence, in particular at younger ages. Read More

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January 2019
4 Reads
1.599 Impact Factor

Co-existence of Rolandic and 3 Hz Spike-Wave Discharges on EEG in Children with Epilepsy.

Can J Neurol Sci 2019 Jan 3;46(1):64-70. Epub 2018 Dec 3.

1Department of Pediatrics, Division of Neurology,BC Children's Hospital,Vancouver, British Columbia,Canada.

Objective: Benign epilepsy of childhood with central temporal spikes (BECTS) and absence epilepsy are common epilepsy syndromes in children with similar age of onset and favorable prognosis. However, the co-existence of the electrocardiogram (EEG) findings of rolandic spike and 3 Hz generalized spike-wave (GSW) discharges is extremely rare, with few cases reported in the literature. Our objective was to characterize the EEG findings of these syndromes in children in our center and review the electro-clinical features. Read More

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January 2019
2 Reads

Reducing Door-to-Needle Times for Ischaemic Stroke to a Median of 30 Minutes at a Community Hospital.

Can J Neurol Sci 2019 Jan 5;46(1):51-56. Epub 2018 Dec 5.

3Hotchkiss Brain Institute,University of Calgary,Calgary, Alberta,Canada.

Background: Alteplase is an effective treatment for ischaemic stroke patients, and it is widely available at all primary stroke centres. The effectiveness of alteplase is highly time-dependent. Large tertiary centres have reported significant improvements in their door-to-needle (DTN) times. Read More

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http://dx.doi.org/10.1017/cjn.2018.368DOI Listing
January 2019
2 Reads

Narrative Review of the Pathophysiology of Headaches and Photosensitivity in Mild Traumatic Brain Injury and Concussion.

Can J Neurol Sci 2019 Jan 4;46(1):14-22. Epub 2018 Dec 4.

Ophtalmology Department,Centre Hospitalier de l'Université de Montréal,Montreal, Quebec,Canada.

The most common symptom of post-concussive syndrome (PCS) is post-traumatic headache (PTH) accompanied by photophobia. Post-traumatic headache is currently categorized as a secondary headache disorder with a clinical phenotype described by its main features and resembling one of the primary headache disorders: tension, migraine, migraine-like cluster. Although PTH is often treated with medication used for primary headache disorders, the underlying mechanism for PTH has yet to be elucidated. Read More

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January 2019
8 Reads

Profound Leptomeningeal and Intramedullary Abnormalities in Bing-Neel Syndrome.

Can J Neurol Sci 2019 Jan 29;46(1):102-104. Epub 2018 Nov 29.

3Department of Medical Imaging,The Ottawa Hospital,Ottawa,Ontario,Canada.

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January 2019
22 Reads

Myelitis with Hypoglycorrhachia due to Herpes Simplex Virus 2 in an Immunocompetent Man.

Can J Neurol Sci 2019 Jan 21;46(1):147-148. Epub 2018 Nov 21.

2Division of Neurology, Department of Medicine,Hamilton Health SciencesHamilton,ON,Canada.

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http://dx.doi.org/10.1017/cjn.2018.365DOI Listing
January 2019
11 Reads

Progressive Supranuclear Palsy-like Syndrome from Possible Cerebral Amyloid Angiopathy.

Can J Neurol Sci 2019 Jan 20;46(1):132-136. Epub 2018 Nov 20.

Division of Neurology, Department of Medicine,University of Alberta,Edmonton, Alberta,Canada.

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http://dx.doi.org/10.1017/cjn.2018.367DOI Listing
January 2019
7 Reads

Evidence of Concomitantly Increasing Stroke and Dementia Prevalence among those 80 Years and Older in Ontario, Canada, 2003-04 to 2012-13.

Can J Neurol Sci 2019 Jan 19;46(1):105-107. Epub 2018 Nov 19.

1Department of Clinical Neurological Sciences,London Health Sciences Centre,Western University,London,Ontario,Canada.

Among those aged 80 years and older in Ontario, Canada, stroke and dementia incidence declined concomitantly from 2002-03 to 2013-14. This study aimed to report the concurrent temporal trends of stroke and dementia prevalence in Ontario among the same age demographic. The prevalence of both stroke and dementia increased from 2003-04 to 2012-13 in both sexes and the magnitude in which prevalence of dementia increased over time exceeded that of stroke. Read More

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January 2019
1 Read

Atypical Clinical Presentation and Imaging Findings of Central Nervous System Tuberculosis.

Can J Neurol Sci 2018 Nov;45(6):686-687

1Division of Neurology,Department of Medicine,University of Toronto,Toronto,Ontario,Canada.

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November 2018
9 Reads

Recurrent Amoxicillin-Induced Aseptic Meningitis.

Can J Neurol Sci 2018 Nov;45(6):701-702

Department of Medicine (Neurology),Memorial University of Newfoundland,St. John's,Newfoundland and Labrador, Canada.

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November 2018
1 Read

Epilepsy, Physical Activity and Sports: A Narrative Review.

Can J Neurol Sci 2018 Nov;45(6):624-632

5Department of Medicine,Division of Neurology,Saskatchewan Epilepsy Program,Royal University Hospital,University of Saskatchewan,Saskatoon,Saskatchewan,Canada.

People with epilepsy (PWE) are less physically active compared with the general population. Explanations include prejudice, overprotection, unawareness, stigma, fear of seizure induction and lack of knowledge of health professionals. At present, there is no consensus on the role of exercise in epilepsy. Read More

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November 2018
9 Reads

Endoscopic Retrieval of Flanged Ventricular Catheters.

Can J Neurol Sci 2018 Nov;45(6):692-695

3Division of Neurosurgery (Department of Surgery),IWK Health Centre,Dalhousie University,Halifax,Canada.

Flanged ventricular catheters are now used infrequently. Many patients with longstanding hydrocephalus still harbor these catheters, either as their current ventricular catheter, or as a retained catheter from a prior implant. The removal of flanged ventricular catheters is sometimes necessary, and may be challenging due to intraventricular adhesions. Read More

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http://dx.doi.org/10.1017/cjn.2018.336DOI Listing
November 2018
1 Read

Research Priorities for Optimizing Long-term Community Integration after Brain Injury.

Can J Neurol Sci 2018 Nov;45(6):643-651

12Department of Kinesiology,University of Waterloo,Waterloo,Ontario,Canada (ENS).

Objective: This paper reports on a funded summit, which convened a multidisciplinary group of experts to provide consensus on the research priorities necessary for improving long-term community integration of individuals with traumatic brain injury (TBI) and their caregivers.

Methods: The 2-day summit was directed using the World Café Methodology, to engage stakeholders and collaboratively arrive at a consensus on the problems to be targeted in research. Participants (n=54), drawn from two Canadian provinces, included an interdisciplinary group of researchers, clinicians, representatives from brain injury associations, individuals with TBI, and caregivers. Read More

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November 2018
7 Reads

Low-Intensity Ultrasound Decreases Ischemia-Induced Edema by Inhibiting N-Methyl-d-Aspartic Acid Receptors.

Can J Neurol Sci 2018 Nov;45(6):675-681

1Department of Biomedical Sciences,Inha University College of Medicine,Incheon,Korea.

Background: We have previously shown that low-intensity ultrasound (LIUS), a noninvasive mechanical stimulus, inhibits brain edema formation induced by oxygen and glucose deprivation (OGD) or treatment with glutamate, a mediator of OGD-induced edema, in acute rat hippocampal slice model in vitro.

Methods: In this study, we treated the rat hippocampal slices with N-methyl-d-aspartic acid (NMDA) or (S)-3,5-dihydroxyphenylglycine (DHPG) to determine whether these different glutamate receptor agonists induce edema. The hippocampal slices were then either sonicated with LIUS or treated with N-methyl-d-aspartic acid receptor (NMDAR) antagonists, namely, MK-801 and ketamine, and observed their effects on edema formation. Read More

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http://dx.doi.org/10.1017/cjn.2018.331DOI Listing
November 2018
22 Reads

Cerebral Perfusion Pressure Targets in Traumatic Brain Injury: The "Fuzzy" Spots Above Optimal Cerebral Perfusion Pressure.

Can J Neurol Sci 2018 Nov;45(6):721-722

1Department of Surgery,Rady Faculty of Health Sciences,University of Manitoba,Winnipeg,Manitoba,Canada.

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November 2018
13 Reads

An Evaluation of the Family Informal Caregiver Stroke Self-Management Program.

Can J Neurol Sci 2018 Nov;45(6):660-668

9School of Nursing and Aging,Community and Health Research Unit,McMaster University,Hamilton,Ontario,Canada.

Background: Caregivers are often unprepared and overwhelmed with the responsibilities of providing care to stroke survivors, which can lead to negative physical and psychological effects.

Purpose: To evaluate the impact of the Family Informal Caregiver Stroke Self-Management (FICSS) program on burden and life changes resulting from providing care among family caregivers of stroke survivors.

Methods: A prospective pre-test and post-test design using quantitative and qualitative data was used to evaluate the program with a convenience sample of 42 caregivers. Read More

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http://dx.doi.org/10.1017/cjn.2018.335DOI Listing
November 2018
27 Reads

Concussion, Cagney, Captains of the Clouds.

Authors:
Donald F Weaver

Can J Neurol Sci 2018 Nov;45(6):682-685

Krembil Research Institute,University Health Network,Toronto,Ontario,Canada.

The case of James Cagney adds interesting details to the history of concussion. It is underappreciated that a movie-star of Cagney's stature incurred multiple concussions over many years. Moreover, the fact that he sustained one of these concussions in Canada while filming Captains of the Clouds, a major Hollywood film, is essentially unknown, and was seldom discussed by Cagney despite his willingness to discuss his many other concussions. Read More

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November 2018
10 Reads

Neuromuscular Ultrasound: Clinical Applications and Diagnostic Values.

Can J Neurol Sci 2018 Nov;45(6):605-619

2Department of Neurology and Clinical Neurophysiology,Donders Institute for Brain,Cognition and Behaviour,Radboud University Medical Center,Nijmegen,The Netherlands.

Advances in high-resolution ultrasound have provided clinicians with unique opportunities to study diseases of the peripheral nervous system. Ultrasound complements the clinical and electrophysiology exam by showing the degree of abnormalities in myopathies, as well as spontaneous muscle activities in motor neuron diseases and other disorders. In experienced hands, ultrasound is more sensitive than MRI in detecting peripheral nerve pathologies. Read More

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http://dx.doi.org/10.1017/cjn.2018.314DOI Listing
November 2018
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Selegiline in Patients With Disorder of Consciousness: An Open Pilot Study.

Can J Neurol Sci 2018 Nov;45(6):688-691

1Maugeri Scientific and Clinical Institutes,IRCCS,Disorders of Consciousness Laboratory,Institute of Telese Terme,Telese Terme,Benevento,Italy.

This open study investigated the clinical effects of 10-week selegiline administration in six patients in vegetative state and in four patients in a minimally conscious state, at least 6 months after onset. Clinical outcome was assessed by Coma Recovery Scale-Revised once a week during selegiline administration and 1 month later. Three patients stopped treatment because of possible side effects. Read More

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https://www.cambridge.org/core/product/identifier/S031716711
Publisher Site
http://dx.doi.org/10.1017/cjn.2018.315DOI Listing
November 2018
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Provincial Differences in the Diagnosis and Care of Amyotrophic Lateral Sclerosis.

Can J Neurol Sci 2018 Nov;45(6):652-659

1Department of Clinical Neurosciences, and Hotchkiss Brain Institute,University of Calgary,Calgary,Alberta,Canada.

Background: Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease resulting in muscle weakness, dysarthria and dysphagia, and ultimately respiratory failure leading to death. Half of the ALS patients survive less than 3 years, and 80% of the patients survive less than 5 years. Riluzole is the only approved medication in Canada with randomized controlled clinical trial evidence to slow the progression of ALS, albeit only to a modest degree. Read More

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https://www.cambridge.org/core/product/identifier/S031716711
Publisher Site
http://dx.doi.org/10.1017/cjn.2018.311DOI Listing
November 2018
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Patient Predictors of Surgical Candidacy in Elective Spine Disorders.

Can J Neurol Sci 2019 Jan 15;46(1):96-101. Epub 2018 Nov 15.

1Department of Clinical Neurosciences,Section of Neurosurgery,University of Calgary,Calgary,Alberta,Canada.

Background: The expansion of age-related degenerative spine pathologies has led to increased referrals to spine surgeons. However, the majority of patients referred for surgical consultation do not need surgery, leading to inefficient use of healthcare resources. This study aims to elucidate preoperative patient variables that are predictive of patients being offered spine surgery. Read More

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http://dx.doi.org/10.1017/cjn.2018.342DOI Listing
January 2019
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