1,045 results match your criteria The Approach to the Painful Joint


New insights into Behçet's disease in Ireland: the Midwest cohort study.

Clin Exp Rheumatol 2018 Nov-Dec;36 Suppl 115(6):33-39. Epub 2018 Nov 28.

Department of Rheumatology, University Hospital Limerick; Graduate Entry Medical School, University of Limerick; Health Research Institute, University of Limerick, Ireland.

Objectives: The epidemiology of Behçet's disease (BD) remains poorly understood with limited international data on disease burden, progression and treatment outcomes. The aims of this study were to determine the natural history of BD in the Midwest region of Ireland and compare our findings with those from other European and Mediterranean studies.

Methods: We established a cohort of patients with BD in the Midwest Region of Ireland based on ISGBD and/or ICBD criteria. Read More

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November 2018
2 Reads

Diagnosis and Management of Fungal Periprosthetic Joint Infections.

J Am Acad Orthop Surg 2018 Dec 4. Epub 2018 Dec 4.

From the Sinai Hospital of Baltimore, Baltimore, MD (Dr. Nace), the Philadelphia College of Osteopathic Medicine, Philadelphia, PA (Dr. Siddiqi), the New England Baptist Hospital, Boston, MA (Dr. Talmo), and the Brigham and Women's Hospital, Boston, MA (Dr. Chen).

Fungal periprosthetic joint infection (PJI) is a devastating complication because it can be difficult to diagnose, manage, and eradicate. Fungal PJI treatment requires a systematic approach. Increased awareness is essential when patients with painful arthroplasties present with immunosuppression, significant comorbidities, multiple surgeries, and history of drug use. Read More

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http://Insights.ovid.com/crossref?an=00124635-900000000-9945
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http://dx.doi.org/10.5435/JAAOS-D-18-00331DOI Listing
December 2018
7 Reads

Reemerging arboviruses: clinical-epidemiological profile of hospitalized elderly patients.

Rev Esc Enferm USP 2018 Nov 29;52:e03403. Epub 2018 Nov 29.

Universidade Federal da Paraíba, João Pessoa, PB, Brasil.

Objective: Describe the clinical-epidemiological profile of hospitalized elderly patients with arbovirus.

Method: A documentary retrospective population-based descriptive study that used a quantitative approach with hospitalized elderly patients diagnosed with arbovirus was conducted in a teaching hospital. Data were collected from medical records and investigation forms. Read More

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http://dx.doi.org/10.1590/S1980-220X2017052103403DOI Listing
November 2018
2 Reads

Factors associated with prevalent and incident foot pain: data from the Tasmanian Older Adult Cohort Study.

Maturitas 2018 Dec 21;118:38-43. Epub 2018 Oct 21.

Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia. Electronic address:

Objectives: To describe factors associated with prevalent and incident foot pain in a population-based cohort of older adults (n = 1092).

Study Design: Longitudinal observational study.

Main Outcome Measures: Prevalent foot pain, incident foot pain after 5 years. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183037
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http://dx.doi.org/10.1016/j.maturitas.2018.10.004DOI Listing
December 2018
6 Reads

Dorsal buttress plate fixation for the treatment of fracture-dislocation of the fifth carpometacarpal joint with avulsion fracture of the hamate: a case report.

Arch Orthop Trauma Surg 2018 Nov 9. Epub 2018 Nov 9.

Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194, Japan.

Fracture-dislocations of the fourth and fifth carpometacarpal (CMC) joints present a complex situation. Misdiagnosis and inadequate treatment may cause malunion and residual subluxation, which lead to painful arthritis and grip weakness. Open reduction along with internal fixation is the treatment of choice, but there is no consensus on an optimal treatment approach. Read More

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http://link.springer.com/10.1007/s00402-018-3072-0
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http://dx.doi.org/10.1007/s00402-018-3072-0DOI Listing
November 2018
11 Reads

Comparative safety of immune checkpoint inhibitors in cancer: systematic review and network meta-analysis.

BMJ 2018 Nov 8;363:k4226. Epub 2018 Nov 8.

Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou 510060, China

Objective: To provide a complete toxicity profile, toxicity spectrum, and a safety ranking of immune checkpoint inhibitor (ICI) drugs for treatment of cancer.

Design: Systematic review and network meta-analysis.

Data Sources: Electronic databases (PubMed, Embase, Cochrane Library, and Web of Science) were systematically searched to include relevant studies published in English between January 2007 and February 2018. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222274PMC
http://dx.doi.org/10.1136/bmj.k4226DOI Listing
November 2018
10 Reads

Surgical Management of Proximal Long Head Biceps Tendon Disorders.

Authors:
Richard L Angelo

Sports Med Arthrosc Rev 2018 Dec;26(4):176-180

ProOrtho Clinic, Kirkland, Washington.

Disorders of the long head of the biceps tendon can make a significant contribution to shoulder pain and dysfunction. Historically, open biceps tenotomy or a proximal tenodesis of the tendon through a deltopectoral approach was used to manage biceps tendonitis and instability. Recent developments have added additional options. Read More

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http://dx.doi.org/10.1097/JSA.0000000000000197DOI Listing
December 2018
6 Reads

ACR Appropriateness Criteria Management of Vertebral Compression Fractures.

J Am Coll Radiol 2018 Nov;15(11S):S347-S364

Specialty Chair (Neurological), UC San Diego Health, San Diego, California.

Vertebral compression fractures (VCFs) have various causes, including osteoporosis, neoplasms, and acute trauma. As painful VCFs may contribute to general physical deconditioning, management of painful VCFs has the potential for improving quality of life and preventing superimposed medical complications. Various imaging modalities can be used to evaluate a VCF to help determine the etiology and guide intervention. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15461440183116
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http://dx.doi.org/10.1016/j.jacr.2018.09.019DOI Listing
November 2018
4 Reads

Characterization of chronic clinical manifestations in patients with chikungunya fever

Rev Med Inst Mex Seguro Soc 2018 Oct 25;56(3):239-245. Epub 2018 Oct 25.

Instituto Mexicano del Seguro Social, Unidad de Medicina Familiar No. 9, Curso de Especialización en Medicina Familiar. Acapulco, Guerrero, México

Background: In Mexico there are no studies concerning the chronicity of clinical manifestations of chikungunya fever (CHIK).

Objective: To describe the characterization of chronic clinical manifestations in patients with chikungunya fever from the Unidad de Medicina Familiar No.9 (UMF No. Read More

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October 2018
2 Reads

Tenodesis of the Ulnotriquetrum Ligament to the Fovea for a Triangular Fibrocartilage Complex Tear.

Tech Hand Up Extrem Surg 2018 Dec;22(4):141-145

Yukioka Hospital Hand Center, Osaka, Japan.

We developed a novel procedure to treat a triangular fibrocartilage complex (TFCC) foveal tear, namely tenodesis of the ulnotriquetrum ligament (UTL) to the fovea. We attempted to reestablish the tension of the palmar radioulnar ligament by the procedure specifically in cases with palmar radius instability relative to the ulna. We used a palmar surgical approach to expose the palmar aspect of TFCC in which the ulnocarpal ligament merges with the palmar radioulnar ligament. Read More

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http://dx.doi.org/10.1097/BTH.0000000000000212DOI Listing
December 2018
2 Reads

Imaging of joints in systemic lupus erythematosus.

Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):68-73. Epub 2018 Oct 1.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

Musculoskeletal symptoms are among the most common manifestations in patients with systemic lupus erythematosus (SLE), being reported in up to 95% of patients; joint and tendon involvement can range from arthralgia to severe deforming arthropathy; while myositis a rare manifestation, comorbid fibromyalgia is reported in up to 40% of SLE patients. All these manifestations have a significant impact on the patients' quality of life, possibly leading to disability and functional impairment in daily living activities. In recent years, thanks to the availability of new imaging techniques for the assessment of tendon and joint pathologies, the approach to the definition and characterisation of these manifestations in SLE is constantly evolving. Read More

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January 2019
3 Reads

Pain coping skills training for African Americans with osteoarthritis study: baseline participant characteristics and comparison to prior studies.

BMC Musculoskelet Disord 2018 Sep 19;19(1):337. Epub 2018 Sep 19.

Department of Psychology, East Carolina University, Greenville, NC, USA.

Background: The Pain Coping Skills Training for African Americans with OsteoaRTthritis (STAART) trial is examining the effectiveness of a culturally enhanced pain coping skills training (CST) program for African Americans with osteoarthritis (OA). This disparities-focused trial aimed to reach a population with greater symptom severity and risk factors for poor pain-related outcomes than previous studies. This paper compares characteristics of STAART participants with prior studies of CST or cognitive behavioral therapy (CBT)-informed training in pain coping strategies for OA. Read More

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http://dx.doi.org/10.1186/s12891-018-2249-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145122PMC
September 2018

Predicting the outcome of conservative treatment with physiotherapy in adults with shoulder pain associated with partial-thickness rotator cuff tears - a prognostic model development study.

BMC Musculoskelet Disord 2018 Sep 11;19(1):329. Epub 2018 Sep 11.

schulter-zentrum.com, Hamburg, Germany.

Background: Rotator cuff disorders represent the commonest type of painful shoulder complaints in clinical practice. Although conservative treatment including physiotherapy is generally recommended as first-line treatment, little is known about the precise treatment indications for subgroups of rotator cuff disorders, particularly people with shoulder pain associated with partial-thickness tears of the rotator cuff, PTTs: "symptomatic PPTs". The aim of this study was to develop a prognostic model for predicting the outcome of a phase of conservative treatment primarily with physiotherapy in adults with symptomatic PTTs. Read More

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http://dx.doi.org/10.1186/s12891-018-2239-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134519PMC
September 2018
7 Reads

Symptomatic, Unstable Os Acromiale.

J Am Acad Orthop Surg 2018 Nov;26(22):789-797

From the Department of Orthopaedics, University of Maryland Medical Center, Baltimore, MD.

Management of a persistently symptomatic, unstable os acromiale remains controversial. An unstable os acromiale is an easy diagnosis to miss and should be specifically evaluated for in patients with shoulder pain and a high degree of clinical suspicion. Surgical options include open or arthroscopic excision and open reduction and internal fixation. Read More

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http://Insights.ovid.com/crossref?an=00124635-201811150-0000
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http://dx.doi.org/10.5435/JAAOS-D-17-00011DOI Listing
November 2018
3 Reads

Surgical Treatment of Subfibular Ossicle in Children: A Retrospective Study of 36 Patients with Functional Instability.

J Pediatr Orthop 2018 Oct;38(9):e524-e529

Paediatric Orthopaedic Surgery Angers University Hospital, Angers.

Backgrounds: To evaluate the surgical management of a symptomatic subfibular ossicle after severe ankle sprain with functional instability and pain sequelae in children.

Methods: We analyzed 36 patients complaining of functional instability without laxity, 1 year after an ankle inversion trauma associated with the observation of a subfibular ossicle. We systematically suggested the open excision of the residual ossicles, followed by 6 weeks of immobilization and proprioceptive physiotherapy. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001229DOI Listing
October 2018
1 Read

A Comprehensive Look at Irritable Bowel Syndrome and its Associated Factors Considering the Rome IV Criteria: A Penalized Smoothly Clipped Absolute Deviation Regression Approach in the Pars Cohort Study.

Middle East J Dig Dis 2018 Jul 22;10(3):149-159. Epub 2018 Jun 22.

Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

BACKGROUND After the introduction of the Rome IV criteria for the diagnosis of irritable bowel syndrome (IBS), studies on the clinical significance of the new criteria in the settings of a large study has been scarce. Herein we used the infrastructures provided by one the largest cohort studies in Iran to evaluate the epidemiological features related to IBS. METHODS A total of 9264 participants, were enrolled in the initial registry. Read More

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http://dx.doi.org/10.15171/mejdd.2018.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119837PMC
July 2018
68 Reads

Hyaline fibromatosis syndrome: Clinical update and phenotype-genotype correlations.

Hum Mutat 2018 Dec 17;39(12):1752-1763. Epub 2018 Sep 17.

Department of Genetic and Molecular Medicine, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.

Hyaline fibromatosis syndrome (HFS) is the unifying term for infantile systemic hyalinosis and juvenile hyaline fibromatosis. HFS is a rare autosomal recessive disorder of the connective tissue caused by mutations in the gene for anthrax toxin receptor-2 (ANTXR2). It is characterized by abnormal growth of hyalinized fibrous tissue with cutaneous, mucosal, osteoarticular, and systemic involvement. Read More

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http://dx.doi.org/10.1002/humu.23638DOI Listing
December 2018
14 Reads

Combined arthroscopic and open operative management of an intramuscular supraspinatus lipoma in the treatment of subacromial impingement syndrome: A case report.

Int J Surg Case Rep 2018 13;51:147-149. Epub 2018 Aug 13.

University Hospital Geelong, Barwon Health, Geelong, VIC, Australia; Barwon Centre of Orthopaedic Research and Education (B-CORE), Barwon Health and St John of God Hospital, Geelong, VIC, Australia; School of Medicine, Deakin University, Waurn Ponds, Geelong, VIC, Australia.

Introduction: Subacromial impingement syndrome (SAIS) is one cause of shoulder pain and encompasses a spectrum of pathologies and is not an isolated entity.

Presentation Of Case: We present a rare case where a 40 year old male presented with a 3 year history of right shoulder tip pain with limited abduction to 30°, external rotation to 45°, preserved internal rotation and forward flexion and a painful arc with positive Neers and Hawkins-Kennedy signs for impingement consistent with SAIS. The presentation occurred in the setting of a supraspinatus intramuscular lipoma demonstrated on shoulder MRI. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122152PMC
August 2018
4 Reads

Evaluation of a New Exercise Program in the Treatment of Scapular Dyskinesis.

Int J Sports Med 2018 Oct 27;39(10):782-790. Epub 2018 Aug 27.

Sportklinik-Stuttgart, Department Sportorthopädie/Sporttraumatologie Obere Extremität/Schulterprothetik/, Stuttgart, Germany.

An abnormal motion of the scapula, or scapular dyskinesis (SD), can be effectively treated through conservative therapy. The aim of this study is to evaluate a new specific exercise program to restore normal position. A standardized and specific exercise program was created. Read More

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http://dx.doi.org/10.1055/a-0608-4584DOI Listing
October 2018
13 Reads

Evaluation of Temporomandibular Disorders and Comorbidities in Patients with Ehler--Danlos: Clinical and Digital Findings.

J Int Soc Prev Community Dent 2018 Jul-Aug;8(4):333-338. Epub 2018 Jul 18.

Department of Oral and Maxillofacial Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.

Objective: The objective of this study is to recognize representative cranio-cervico-mandibular features of patients with Ehler-Danlos syndrome and associated temporomandibular disorders (TMDs), to assess a targeted and integrated treatment plan.

Materials And Methods: After a diagnosis of disease, 38 individiuals with Ehler-Danlos syndrome and temporomandibular symptomatology referred were evaluated. Gnathological evaluation, according to the Diagnostic Criteria for TMDs, and radiographic imaging was performed. Read More

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http://dx.doi.org/10.4103/jispcd.JISPCD_103_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071363PMC
July 2018
2 Reads

Micronized palmitoylethanolamide reduces joint pain and glial cell activation.

Inflamm Res 2018 Oct 18;67(10):891-901. Epub 2018 Aug 18.

Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166, Messina, Italy.

Objective And Design: Temporomandibular disorder (TMD) is a common painful condition in the temporomandibular joint (TMJ). Joint inflammation is believed to be a chief cause of pain in patients with TMD, through the release of pro-inflammatory cytokines that induce peripheral sensitization of nerve terminals followed by microglial stimulation.

Materials And Subject: TMJ was induced in rats with the injection of complete Freund's adjuvant (CFA) emulsion into the left TMJ capsule. Read More

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http://dx.doi.org/10.1007/s00011-018-1179-yDOI Listing
October 2018
18 Reads

Antiviral activity of silymarin against Mayaro virus and protective effect in virus-induced oxidative stress.

Antiviral Res 2018 Oct 1;158:8-12. Epub 2018 Aug 1.

Núcleo de Pesquisas em Ciências Biológicas, NUPEB, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Departamento de Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil. Electronic address:

Mayaro virus (MAYV) is a neglected arbovirus belonging to the family Togaviridae. Its infection leads to Mayaro fever, with clinical manifestations such as fever, myalgia, headache, rash, arthralgia, vomiting, and diarrhea. The most prominent complaint from infected person is the long-lasting arthritis/arthralgia. Read More

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http://dx.doi.org/10.1016/j.antiviral.2018.07.023DOI Listing
October 2018
16 Reads

Adamantiades-Behçet Disease at the Beginning of the Silk Route: North-East Italian Experience.

Acta Dermatovenerol Croat 2017 Dec;25(4):295-297

Nicola di Meo, MD, Dermatology Department, University of Trieste, Ospedale Maggiore di Trieste, Piazza Ospedale 1, IV Piano Palazzina Infettivi, 34100 Trieste, Italy;

Dear Editor, Adamantiades-Behçet's disease (ABD) is an inflammatory disease classified as vasculitis, which was originally diagnosed in patients with aphthous stomatitis, genital ulcerations, and ocular manifestations. However, any organ or system may be involved, particularly the central and peripheral nervous systems, joints, as well as the gastrointestinal tract. The etiology of ABD is still not fully understood, but some evidence indicates that an autoimmune process could be triggered by an infectious or environmental agent specific for the geographic region (1). Read More

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December 2017
4 Reads

Synovial involvement assessed by power Doppler ultra-sonography in systemic sclerosis: results of a cross-sectional study.

Rheumatology (Oxford) 2018 Nov;57(11):2012-2021

Department of Rheumatology, Centre Hospitalier Universitaire de Rennes, Rennes, France.

Objectives: To characterize hand synovial manifestations assessed by power Doppler ultrasonography (PDUS) in a cohort of unselected patients fulfilling the 2013 ACR/EULAR classification criteria for SSc and to evaluate the associations of these synovial manifestations with the main general clinical and biological features of SSc.

Methods: One hundred and three SSc patients were consecutively included and underwent PDUS evaluation of both hands assessing synovial and tenosynovial manifestations according to the OMERACT definitions. Clinical, biological and immunological SSc characteristics were recorded at the same time. Read More

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http://dx.doi.org/10.1093/rheumatology/key214DOI Listing
November 2018
4 Reads

Tibial Tubercle Osteotomy in Total Knee Arthroplasty: Midterm Results Experience of a Monocentric Study.

Joints 2018 Jun 22;6(2):95-99. Epub 2018 Jun 22.

U.O. Ortopedia, Clinica Città di Alessandria - Policlinico di Monza, Alessandria, Italy.

 Difficult primary total knee arthroplasty (TKA) and revision TKA may be high demanding, especially during joint exposure. Aim of this article is to evaluate the clinical and radiological outcomes of a series of patients, who underwent TKA and revision TKA, where tibial tubercle osteotomy (TTO) was performed.  We retrospectively reviewed a cohort of 79 consecutives TKAs where TTO was performed. Read More

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http://dx.doi.org/10.1055/s-0038-1661338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059855PMC
June 2018
2 Reads

The Approach to the Child with Joint Complaints.

Pediatr Clin North Am 2018 08;65(4):623-638

Pediatric Immunology, Section of Pediatric Rheumatology and Immunology, Department of Pediatrics, Seton Hall-Hackensack Meridian School of Medicine, Hackensack University Medical Center, 30 Prospect Avenue, Room WFAN 360, Hackensack, NJ 07601, USA. Electronic address:

This article focuses on creating an orderly approach to history taking, examination, and ordering appropriate investigations when caring for a child with joint complaints. It classifies complaints as those with and without pain, swelling, or fever and of short or long duration. It recommends an approach to the physical examination and both suggests and discourages various laboratory and imaging studies. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.03.003DOI Listing
August 2018
1 Read

Kikuchi-Fujimoto disease in children: two case reports and a review of the literature.

Ital J Pediatr 2018 Jul 18;44(1):83. Epub 2018 Jul 18.

Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Background: Kikuchi-Fujimoto disease is a rare, idiopathic and generally self-limiting cause of lymphadenitis of unknow etiology with a low recurrence rate. The typical clinical signs are cervical lymphadenopathy, fever, and symptoms of respiratory infection, and less frequently chills, night sweats, arthralgia, rash, and weight loss.

Case Presentation: Here we describe two case reports of Kikuchi Fujimoto disease presenting in Milan within the space of a few months. Read More

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http://dx.doi.org/10.1186/s13052-018-0522-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052688PMC
July 2018
4 Reads

Surgical Versus Nonsurgical Management of Degenerative Joint Disease.

Oral Maxillofac Surg Clin North Am 2018 Aug 5;30(3):291-297. Epub 2018 Jul 5.

Department of Oral and Maxillofacial Surgery, Virginia Commonwealth University School of Dentistry, Wood Building Room 311C, 520 North 12th Street, Richmond, VA 23298, USA. Electronic address:

As knowledge of the complexity of myofascial pain and its interaction with temporomandibular joint disorders has increased, the use of surgical procedures to treat degenerative joint disease has decreased. The focus has moved from a "surgery-first" approach toward a more cautious one that involves nonsurgical treatment as the primary modality, then minimally invasive treatments, followed by open surgical modalities, when indicated. This article examines the current literature regarding the effectiveness of nonsurgical and surgical treatments for the management of degenerative joint disease. Read More

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http://dx.doi.org/10.1016/j.coms.2018.04.005DOI Listing
August 2018
3 Reads

Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult: An Update.

Authors:
Nora Taylor

Rheum Dis Clin North Am 2018 Aug 12;44(3):513-524. Epub 2018 Jun 12.

Division of Rheumatology, Mid-Atlantic Permanente Medical Group, 6501 Loisdale Court, Springfield, VA 22150, USA. Electronic address:

Symptomatic knee osteoarthritis is a common complaint of many elderly patients in primary care offices. For those unable or unwilling to undergo knee replacement, the primary practitioners' understanding of the strengths and weaknesses of the available treatment modalities for pain relief is critical to successful in-office counseling and expectation management. Treatment requires a multimodal approach of nonpharmacologic and pharmacologic therapies to achieve a maximal clinical benefit. Read More

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http://dx.doi.org/10.1016/j.rdc.2018.03.009DOI Listing
August 2018
3 Reads

Sitosterolemia: diagnosis, metabolic and hematological abnormalities, cardiovascular disease and management.

Curr Med Chem 2018 Jul 5. Epub 2018 Jul 5.

Hospital Universitario de Salamanca-IBSAL-USAL - Department of Hematology Salamanca. Spain.

Sitosterolemia is a recessive inherited metabolic disorder of unknown prevalence, characterized by increased levels of plasma plant sterols. It is caused by 28 and 31 variants in ABCG5 and ABCG8 genes, respectively, and is characterized by a predisposition to hyperabsorption and accumulation of toxic levels of plant sterols in plasma. Its clinical picture is extremely heterogeneous. Read More

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http://dx.doi.org/10.2174/0929867325666180705145900DOI Listing
July 2018
7 Reads

Biomechanical Characteristics of Three Baseplate Rotational Arrangement Techniques in Total Knee Arthroplasty.

Biomed Res Int 2018 6;2018:9641417. Epub 2018 Jun 6.

Department of Mechanical Engineering, Sejong University, Seoul, Republic of Korea.

Introduction: Several ongoing studies aim to improve the survival rate following total knee arthroplasty (TKA), which is an effective orthopedic surgical approach for patients with severely painful knee joint diseases. Among the studied strategies, baseplate rotational arrangement techniques for TKA components have been suggested but have been the subject of only simple reliability evaluations. Therefore, this study sought to evaluate comparatively three different baseplate rotational arrangement techniques that are commonly used in a clinical context. Read More

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http://dx.doi.org/10.1155/2018/9641417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011160PMC
January 2019
2 Reads

The association between pain beliefs and pain intensity and/or disability in people with shoulder pain: A systematic review.

Musculoskelet Sci Pract 2018 10 28;37:29-57. Epub 2018 Jun 28.

Department of Physiotherapy, University of Malaga, Malaga, Spain.

Background: Pain beliefs might play a role in the development, transition, and perpetuation of shoulder pain.

Objective: To systematically review and critically appraise the association and the predictive value of pain beliefs on pain intensity and/or disability in shoulder pain.

Methods: An electronic search of PubMed, EBSCOhost, AMED, CINAHL, EMBASE, and PubPsych, and grey literature was searched from inception to July 2017. Read More

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http://dx.doi.org/10.1016/j.msksp.2018.06.010DOI Listing
October 2018
4 Reads

Management of a nonathlete with a traumatic groin strain and osteitis pubis using manual therapy and therapeutic exercise: A case report.

Physiother Theory Pract 2018 Jul 6:1-8. Epub 2018 Jul 6.

c Rush University Medical Center , Chicago , IL , USA.

Introduction: Without a definitive single pathoanatomical origin for groin pain, management is difficult. The purpose of this case report is to describe the differential diagnosis and management of an individual with a traumatic groin strain.

Case Description: A 47-year-old sedentary male truck driver presented to physical therapy with a 2-month history of right medial groin pain. Read More

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http://dx.doi.org/10.1080/09593985.2018.1492658DOI Listing
July 2018
21 Reads

Prehospital ultrasound-guided nerve blocks improve reduction-feasibility of dislocated extremity injuries compared to systemic analgesia. A randomized controlled trial.

PLoS One 2018 2;13(7):e0199776. Epub 2018 Jul 2.

Department of Anesthesiology, Emergency and Intensive Care Medicine, University Medical Center, University of Goettingen, Goettingen, Germany.

Background: Out-of-hospital analgosedation in trauma patients is challenging for emergency physicians due to associated complications. We compared peripheral nerve block (PNB) with analgosedation (AS) as an analgetic approach for patients with isolated extremity injury, assuming that prehospital required medical interventions (e.g. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028078PMC
January 2019

Chikungunya in Children: A Clinical Review.

Pediatr Emerg Care 2018 Jul;34(7):510-515

Assistant Professor of Pediatrics (Chapman), Division of Pediatric Emergency Medicine, Department of Pediatrics, Children's National Health System, George Washington University School of Medicine and Health Sciences, Washington DC.

Chikungunya (CHIKV) is an emerging arboviral infection with recent spikes in transmission in the Americas. Chikungunya is most commonly transmitted by mosquitos, specifically Aedes aegypti and Aedes albopictus. These mosquitoes are found throughout many parts of the United States. Read More

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http://dx.doi.org/10.1097/PEC.0000000000001529DOI Listing
July 2018
2 Reads

Selective Thumb Carpometacarpal Joint Denervation for Painful Arthritis: Clinical Outcomes and Cadaveric Study.

J Hand Surg Am 2019 Jan 20;44(1):64.e1-64.e8. Epub 2018 Jun 20.

Department of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address:

Purpose: To determine the innervation pattern to the thumb carpometacarpal (CMC) joint and assess the safety and efficacy of selective joint denervation for the treatment of pain and impairment associated with thumb CMC arthritis.

Methods: Cadaveric dissections were performed in 10 fresh upper extremities to better define the innervation patterns to the CMC joint and guide the surgical approach for CMC joint denervation. Histologic confirmation of candidate nerves was performed with hematoxylin and eosin staining. Read More

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http://dx.doi.org/10.1016/j.jhsa.2018.04.030DOI Listing
January 2019
3 Reads

Calcaneal Fractures - Should We or Should We not Operate?

Indian J Orthop 2018 May-Jun;52(3):220-230

Michigan Orthopedic Center, Sparrow Hospital, Lansing, MI, USA.

The best treatment for displaced, intraarticular fractures of the calcaneum remains controversial. Surgical treatment of these injuries is challenging and have a considerable learning curve. Studies comparing operative with nonoperative treatment including randomized trials and meta-analyses are fraught with a considerable number of confounders including highly variable fracture patterns, soft-tissue conditions, patient characteristics, surgeon experience, limited sensitivity of outcome measures, and rehabilitation protocols. Read More

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http://dx.doi.org/10.4103/ortho.IJOrtho_555_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961258PMC
June 2018
24 Reads

Arthroscopic Identification and Management of Recurrent Iliopsoas Impingement After Total Hip Arthroplasty.

Arthrosc Tech 2018 Apr 12;7(4):e349-e353. Epub 2018 Mar 12.

Ramsay Générale de Santé, Hôpital Privé Jean Mermoz, Centre Orthopédique Santy, Lyon, France.

Arthroscopic release of the iliopsoas tendon for iliopsoas impingement (IPI) after total hip arthroplasty (THA) at the lesser trochanter gives good results. However, where IPI then recurs, due to adhesions between the healing iliopsoas tendon and the surrounding soft tissue, and nonoperative measures have failed, a revision THA procedure is usually considered. We propose a technique of arthroscopic visualization of the recurrent IPI and a subsequent psoas tenotomy at the level of the hip joint using an outside-in capsulotomy approach. Read More

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http://dx.doi.org/10.1016/j.eats.2017.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981837PMC
April 2018
4 Reads

Mesenchymal Stem Cell Applications for Joints in the Foot and Ankle.

Clin Podiatr Med Surg 2018 Jul;35(3):323-330

Division of Podiatric Surgery, Department of Surgery, Cambridge Health Alliance, Harvard Medical School, 1493 Cambridge Street, Floor 2, Cambridge, MA 02139, USA. Electronic address:

The use of mesenchymal stem cell injections is a new approach to the treatment of painful joints, particularly in the foot and ankle. Previous studies performed in the knee have considered allogeneic and xenogeneic injections, and autologous cells expanded in culture. This article considers these applications and considers the possibility of performing these types of injections in the foot and ankle joints. Read More

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http://dx.doi.org/10.1016/j.cpm.2018.02.007DOI Listing
July 2018
6 Reads

The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies.

Viruses 2018 05 30;10(6). Epub 2018 May 30.

Laboratory of Molecular RNA Virology & Antiviral Strategies, Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University Health System, 5 Science Drive 2, National University of Singapore, Singapore 117597, Singapore.

Chikungunya virus (CHIKV) has re-emerged as one of the many medically important arboviruses that have spread rampantly across the world in the past decade. Infected patients come down with acute fever and rashes, and a portion of them suffer from both acute and chronic arthralgia. Currently, there are no targeted therapeutics against this debilitating virus. Read More

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http://www.mdpi.com/1999-4915/10/6/294
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http://dx.doi.org/10.3390/v10060294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024654PMC
May 2018
5 Reads

Clinical Outcomes of Patients With Lateral Femoral Cutaneous Nerve Injury After Direct Anterior Total Hip Arthroplasty.

J Arthroplasty 2018 09 24;33(9):2919-2926.e1. Epub 2018 Apr 24.

Emory University School of Medicine, Atlanta, Georgia.

Background: Direct anterior total hip arthroplasty (THA) is an increasingly utilized and patient-requested approach for arthroplasty carrying a unique set of complications. Injury to the lateral femoral cutaneous nerve (LFCN) can have a wide range of clinical symptoms ranging from hypesthesia to painful paresthesia. Long-term effects of this injury have not been well studied. Read More

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http://dx.doi.org/10.1016/j.arth.2018.04.032DOI Listing
September 2018
3 Reads

Adverse events following single dose treatment of lymphatic filariasis: Observations from a review of the literature.

PLoS Negl Trop Dis 2018 05 16;12(5):e0006454. Epub 2018 May 16.

Infectious Diseases Division, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.

Background: WHO's Global Programme to Eliminate Lymphatic Filariasis (LF) uses mass drug administration (MDA) of anthelmintic medications to interrupt LF transmission in endemic areas. Recently, a single dose combination of ivermectin (IVM), diethylcarbamazine (DEC), and albendazole (ALB) was shown to be markedly more effective than the standard two-drug regimens (DEC or IVM, plus ALB) for achieving long-term clearance of microfilaremia.

Objective And Methods: To provide context for the results of a large-scale, international safety trial of MDA using triple drug therapy, we searched Ovid Medline for studies published from 1985-2017 that reported adverse events (AEs) following treatment of LF with IVM, DEC, ALB, or any combination of these medications. Read More

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http://dx.doi.org/10.1371/journal.pntd.0006454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973625PMC
May 2018
3 Reads

Approach to Patients with Suspected Rheumatic Disease.

Prim Care 2018 Jun;45(2):169-180

Section of Rheumatology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA. Electronic address:

Patients with rheumatic disease may present with a myriad of symptoms, from joint pain and rashes to more subtle findings, such as dry eyes and dry mouth. In this article, the authors review in detail the common presenting symptoms of rheumatic disease along with key features in the history and physical examination to help distinguish these from other disease processes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00954543183000
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http://dx.doi.org/10.1016/j.pop.2018.02.001DOI Listing
June 2018
9 Reads

Behavioural typologies of experienced benefit of psychomotor therapy in patients with chronic shoulder pain: A grounded theory approach.

Complement Ther Clin Pract 2018 May 8;31:229-235. Epub 2018 Mar 8.

Department of Research in Rehabilitation and Health Promotion, Faculty of Health Science, VIA University College, Aarhus, Denmark. Electronic address:

In this study we aimed to develop a theoretical account of the experienced benefit of psychomotor therapy in addition to treatment as usual in patients with chronic shoulder pain. The qualitative study design was based on a grounded theory approach. Open-ended face-to-face interviews were conducted after treatment was completed. Read More

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http://dx.doi.org/10.1016/j.ctcp.2018.03.001DOI Listing
May 2018
7 Reads

An approach to hip pain in a young adult.

BMJ 2018 Apr 19;361:k1086. Epub 2018 Apr 19.

Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1136/bmj.k1086DOI Listing
April 2018
2 Reads

UK-South Asian patients' experiences of and satisfaction toward receiving information about biologics in rheumatoid arthritis.

Patient Prefer Adherence 2018 4;12:489-497. Epub 2018 Apr 4.

School of Social Sciences, Nottingham Trent University, Nottingham, UK.

Background: Rheumatoid arthritis (RA) causes painful joint inflammation and is incurable, but treatments control RA. Drug regimens are complex, and patients often do not take their medication as expected. Poor medication adherence can lead to poorly controlled disease and worse patient outcomes. Read More

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http://dx.doi.org/10.2147/PPA.S153741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894650PMC
April 2018
6 Reads

Effect of arthrocentesis plus platelet-rich plasma and platelet-rich plasma alone in the treatment of temporomandibular joint osteoarthritis: A retrospective matched cohort study (A STROBE-compliant article).

Medicine (Baltimore) 2018 Apr;97(16):e0477

Department of Oral and Maxillofacial Surgery, Tainan Sin Lau Hospital, Tainan, the Presbyterian Church.

Although the research on using platelet-rich plasma (PRP) for temporomandibular joint osteoarthritis (TMJ-OA) has advanced, no unified standards exist for determining the joint use of arthrocentesis and the injection dose and frequency of PRP. This study aimed to compare the efficacy of 2 TMJ-OA treatment approaches, arthrocentesis plus platelet-rich plasma (A+PRP) and PRP alone, and attempted to provide another potential treatment option with a single injection of 2 mL of high-concentration and high-purity PRP.This retrospective matched cohort study enrolled 208 patients who were treated for temporomandibular disorders (TMDs) in the Department of Oral and Maxillofacial Surgery of Tainan Sin-Lau Hospital between August of 2013 and January of 2016, from which 90 patients were selected for the final analysis. Read More

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http://dx.doi.org/10.1097/MD.0000000000010477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916704PMC
April 2018
9 Reads

Quadriceps Function, Knee Pain, and Self-Reported Outcomes in Patients With Anterior Cruciate Ligament Reconstruction.

J Athl Train 2018 Apr 18;53(4):337-346. Epub 2018 Apr 18.

University of Kentucky, Lexington.

Context:   Interactions among muscle strength, pain, and self-reported outcomes in patients with anterior cruciate ligament reconstruction (ACLR) are not well understood. Clarifying these interactions is of clinical importance because improving physical and psychological function is thought to optimize outcomes after ACLR.

Objective:   To examine the relationships among neuromuscular quadriceps function, pain, self-reported knee function, readiness to return to activity, and emotional response to injury both before and after ACLR. Read More

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http://natajournals.org/doi/10.4085/1062-6050-245-16
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http://dx.doi.org/10.4085/1062-6050-245-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967275PMC
April 2018
7 Reads

Design and development of a smart knee pain relief pad based on vibration and alternate heating and cooling treatments.

Technol Health Care 2018 ;26(3):543-551

Knee pain is one of the main health issues faced by different people in different parts of the world. Over one fourth of the people above the age of fifty suffer from knee pain. Though there are several physiotherapy treatments for treating knee pain they are not self-applicable and those which are self-applicable by the patient are not highly efficient. Read More

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http://dx.doi.org/10.3233/THC-181213DOI Listing
December 2018
1 Read

Temporomandibular joint regeneration: proposal of a novel treatment for condylar resorption after orthognathic surgery using transplantation of autologous nasal septum chondrocytes, and the first human case report.

Stem Cell Res Ther 2018 04 7;9(1):94. Epub 2018 Apr 7.

Centro de Medicina Regenerativa, Faculdade de Medicina de Petrópolis - FASE, Avenida Barão do Rio Branco 1003, Centro, Petrópolis, RJ 25680-120, Brazil.

Background: Upon orthognathic mandibular advancement surgery the adjacent soft tissues can displace the distal bone segment and increase the load on the temporomandibular joint causing loss of its integrity. Remodeling of the condyle and temporal fossa with destruction of condylar cartilage and subchondral bone leads to postsurgical condylar resorption, with arthralgia and functional limitations. Patients with severe lesions are refractory to conservative treatments, leading to more invasive therapies that range from simple arthrocentesis to open surgery and prosthesis. Read More

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http://dx.doi.org/10.1186/s13287-018-0806-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889586PMC
April 2018
14 Reads