Neuroradiology 2021 Mar 18. Epub 2021 Mar 18.
Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Purpose: To determine if dynamic susceptibility contrast perfusion MR imaging (DSC-pMRI) can predict significant genomic alterations in glioblastoma (GB).
Methods: A total of 47 patients with treatment-naive GB (M/F: 23/24, mean age: 54 years, age range: 20-90 years) having DSC-pMRI with leakage correction and genomic analysis were reviewed. Mean relative cerebral blood volume (rCBV), maximum rCBV, relative percent signal recovery (rPSR), and relative peak height (rPH) were derived from T2* signal intensity-time curves by ROI analysis. Read More