11,651 results match your criteria Tetralogy of Fallot


Repair of Untreated Older Patients with Tetralogy of Fallot with Major Aortopulmonary Collaterals.

Ann Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Pediatrics, Lucile Packard Children's Hospital Stanford, Clinical and Translational Research Program; Stanford University School of Medicine; Department of Cardiothoracic Surgery, Lucile Packard Children's Hospital Stanford, Clinical and Translational Research Program; Stanford University School of Medicine.

Background: Our programmatic approach to tetralogy of Fallot with major aortopulmonary collaterals emphasizes single-stage unifocalization with complete intracardiac repair during infancy. Little is known about suitability for complete repair in patients beyond infancy. We sought to analyze outcomes of our approach in older patients with previously untreated tetralogy of Fallot with major aortopulmonary collaterals. Read More

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December 2018

Pulmonary valve replacement in patients with repaired tetralogy of Fallot: early results for recovery of right ventricular dilatation and QRS duration

Turk J Med Sci 2018 12 12;48(6):1121-1128. Epub 2018 Dec 12.

Department of Cardiovascular Surgery, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, İstanbul, Turkey

Background/aim: Although pulmonary valve replacement (PVR) improves ventricular function and symptoms, the benefit and optimal timing of PVR are controversial. This study aimed to evaluate early response to PVR for right ventricle (RV) dilatation and QRS duration.

Materials And Methods: Retrospective analysis was performed for 32 patients with repaired tetralogy of Fallot (TOF) between March 2005 and October 2017. Read More

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December 2018

Can Abbreviated Cardiac Magnetic Resonance Imaging Adequately Support Clinical Decision Making After Repair of Tetralogy of Fallot?

Pediatr Cardiol 2018 Dec 11. Epub 2018 Dec 11.

Division of Pediatric Cardiology, University of Nebraska College of Medicine and Children's Hospital and Medical Center, 8200 Dodge St, Omaha, NE, 68114, USA.

Quantification of pulmonary regurgitation (PR), pulmonary flow distribution, and ventricular function is important for clinical surveillance in repaired Tetralogy of Fallot (TOF). Cardiovascular magnetic resonance (CMR) is the established reference, but cost, test duration, and patient discomfort are potential limitations to its serial use. We investigated whether an Abbreviated CMR protocol would alter clinical decisions in TOF from those that would have been made using a full protocol. Read More

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December 2018

Congenital Ventricular Diverticulum or Aneurysm: A Difficult Diagnosis to Make.

Case Rep Cardiol 2018 11;2018:5839432. Epub 2018 Nov 11.

Medical Director, Congenital Cardiac Surgery, Providence Sacred Heart Children's Hospital, 101 W. 8th Avenue Spokane, Washington 99204, USA.

A pouch protruding from the free wall of the left ventricle may be either a congenital ventricular diverticulum (CVD) or aneurysm (CVA). Being aware of these rare congenital anomalies is critical in making the diagnosis. Differentiating the two is important for treatment decisions. Read More

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November 2018
2 Reads

Altered biventricular hemodynamic forces in patients with repaired tetralogy of Fallot and right ventricular volume overload because of pulmonary regurgitation.

Am J Physiol Heart Circ Physiol 2018 Dec 28;315(6):H1691-H1702. Epub 2018 Sep 28.

Lund University, Department of Clinical Sciences, Lund, Clinical Physiology, Skåne University Hospital , Sweden.

Intracardiac hemodynamic forces have been proposed to influence remodeling and be a marker of ventricular dysfunction. We aimed to quantify the hemodynamic forces in patients with repaired tetralogy of Fallot (rToF) to further understand the pathophysiological mechanisms as this could be a potential marker for pulmonary valve replacement (PVR) in these patients. Patients with rToF and pulmonary regurgitation (PR) > 20% ( n = 18) and healthy control subjects ( n = 15) underwent MRI, including four-dimensional flow. Read More

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December 2018
1 Read

4-D flow magnetic-resonance-imaging-derived energetic biomarkers are abnormal in children with repaired tetralogy of Fallot and associated with disease severity.

Pediatr Radiol 2018 Dec 1. Epub 2018 Dec 1.

Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Background: Cardiac MRI plays a central role in monitoring children with repaired tetralogy of Fallot (TOF) for long-term complications. Current risk assessment is based on volumetric and functional parameters that measure late expression of underlying physiological changes. Emerging 4-D flow MRI techniques promise new insights. Read More

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December 2018
3 Reads
1.651 Impact Factor

When is the Best Time for Corrective Surgery in Patients with Tetralogy of Fallot between 0 and 12 Months of Age?

Braz J Cardiovasc Surg 2018 Sep-Oct;33(5):505-510

Universidade de Taubaté (UNITAU), Taubaté, SP, Brazil.

Objective: To identify the best time for corrective surgery of tetralogy of Fallot (TF) in children aged 0-12 months and to report the most frequent complications during the first 3 years postoperatively.

Methods: Systematic review of studies published between 2000 and 2017 on corrective surgery for TF. Articles were selected through search of electronic databases (PubMed, SciELO, Scopus, Lilacs, Google Scholar, and Cochrane). Read More

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November 2017
1 Read

Arrhythmia during diagnostic cardiac catheterization in pediatric patients with congenital heart disease.

Turk Kardiyol Dern Ars 2018 12;46(8):675-682

Department of Pediatric Cardiology, University of Health Sciences, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.

Objective: Diagnostic and interventional cardiac catheterization procedures for congenital heart diseases (CHD) are becoming increasingly more popular, and arrhythmia is a well-known complication. This study was an evaluation of the incidence and causative agents of arrhythmia and the subsequent treatment strategies applied during cardiac catheterization.

Methods: The catheterization data of all of the patients who underwent diagnostic cardiac catheterization for CHD between January 2012 and 2018 at a single center were examined retrospectively. Read More

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December 2018
2 Reads

Assessment of right ventricular systolic function in children with repaired tetralogy of fallot by multiple-view from single acoustic window with speckle tracking echocardiography.

Echocardiography 2018 Dec 4. Epub 2018 Dec 4.

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.

Background: Challenges remain in quantitative evaluation of right ventricular (RV) function by echocardiography. Multiple-view assessment is believed to provide a more comprehensive quantification of RV function than conventional single-view analysis. Peak systolic longitudinal RV strain (RVLS) measured by speckle tracking echocardiography (STE) has clinical and prognostic value. Read More

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December 2018
4 Reads
1.254 Impact Factor

Right ventricular fibrosis is associated with cardiac remodelling after pulmonary valve replacement.

Heart 2018 Dec 4. Epub 2018 Dec 4.

Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada.

Objective: The relationship between right ventricular (RV) fibrosis and right heart reverse remodelling following pulmonary valve replacement (PVR) has not been well studied in adults with repaired tetralogy of Fallot (rTOF). Our aims were to histologically quantify RV fibrosis and to explore the relationship between fibrosis severity and cardiac remodelling post-PVR.

Methods: Adults with rTOF and pre-PVR cardiovascular (CMR) imaging were consented to procurement of RV muscle during PVR. Read More

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December 2018
1 Read

Aortic disease and interventions in adults with tetralogy of Fallot.

Heart 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Background: Aortic dilation and aortic valve disease are known long-term complication of tetralogy of Fallot (TOF), but the risk of aortic dissection and the indications for prophylactic aortic surgery are unknown in this population. The purpose of this study was to: (1) determine the prevalence of significant aortic valve disease and/or significant aortic aneurysm (AVD-AA); (2) determine the incidence of progressive aortic dilation and aortic dissection in patients with TOF.

Methods: Retrospective review of adults with repaired TOF, and no prior aortic valve/aorta surgery, who had ≥2 measurements of the thoracic aorta >12 months apart, 1990-2017. Read More

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December 2018
1 Read

Survey of multinational surgical management practices in tetralogy of Fallot.

Cardiol Young 2018 Dec 4:1-4. Epub 2018 Dec 4.

1Division of Cardiovascular Surgery,Hospital for Sick Children,Toronto,ON,Canada.

Background: A wide variety of surgical strategies are used in tetralogy of Fallot repair. We sought to describe the international contemporary practice patterns for surgical management of tetralogy of Fallot.

Methods: Surgeons from 18 international paediatric cardiac surgery centres (representing over 1800 tetralogy of Fallot cases/year) completed a Research Electronic Data Capture-based survey. Read More

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December 2018
6 Reads

Factors associated with early extubation of patients after corrective tetralogy of Fallot.

Enferm Intensiva 2018 Nov 30. Epub 2018 Nov 30.

División de Estudios de Posgrado, Universidad de la Sierra Sur, Oaxaca, México. Electronic address:

Objective: To assess surgical management and postoperative results associated with early extubation in patients undergoing tetralogy of Fallot corrective surgery at a public hospital in Argentina.

Methods: A retrospective review was made from clinical records from patients who underwent corrective surgery for tetralogy of Fallot. A total of 38 clinical records that met the inclusion criteria for the retrospective review were included in the analysis. Read More

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November 2018
2 Reads

Increased reinterventions after valve-sparing tetralogy of Fallot repair: is it the price to pay?

Authors:
Emile Bacha

Semin Thorac Cardiovasc Surg 2018 Nov 27. Epub 2018 Nov 27.

Irving Medical Center, Columbia University, New York, NY. Electronic address:

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November 2018
1 Read

Echocardiographic Screening for Pulmonary Hypertension in Congenital Heart Disease: JACC Review Topic of the Week.

J Am Coll Cardiol 2018 Dec;72(22):2778-2788

Department of Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom.

Echocardiography is the mainstay in screening for pulmonary hypertension (PH). International guidelines suggest echocardiographic parameters for suspecting PH, but these may not apply to many adults with congenital heart disease (ACHD). PH is relatively common in ACHD patients and can significantly affect their exercise capacity, quality of life, and prognosis. Read More

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December 2018
1 Read
16.503 Impact Factor

Transcatheter Pulmonic Valve Replacement: Progress and Pitfalls.

J Am Coll Cardiol 2018 Dec;72(22):2729-2731

Department of Cardiology, Boston Children's Hospital, Cardiovascular Division, Brigham and Women's Hospital, and Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/DrAdaStefanescu.

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December 2018
1 Read

Endocarditis After Transcatheter Pulmonary Valve Replacement.

J Am Coll Cardiol 2018 Dec;72(22):2717-2728

German Heart Center Munich, Munich, Germany.

Background: Endocarditis has emerged as one of the most concerning adverse outcomes in patients with congenital anomalies involving the right ventricular outflow tract (RVOT) and prosthetic valves.

Objectives: The aim of this study was to evaluate rates and potential risk factors for endocarditis after transcatheter pulmonary valve replacement in the prospective Melody valve trials.

Methods: All patients in whom a transcatheter pulmonary valve (TPV) was implanted in the RVOT as part of 3 prospective multicenter studies comprised the analytic cohort. Read More

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December 2018
1 Read

Implantation of a leadless pacemaker in a pediatric patient with congenital heart disease.

HeartRhythm Case Rep 2018 Nov 1;4(11):506-509. Epub 2018 Aug 1.

Heart Institute, Children's Hospital Orange County, Orange, California.

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November 2018
1 Read

Pulmonary effects on exercise testing in tetralogy of Fallot patients repaired with a transannular patch.

Cardiol Young 2018 Nov 26:1-7. Epub 2018 Nov 26.

The Heart Institute,Cincinnati Children's Hospital Medical Center,Cincinnati, OH,USA.

Background: A transannular patch is often used in the contemporary surgical repair of tetralogy of Fallot. This can lead to significant pulmonary insufficiency and increased right ventricular volumes and ultimately pulmonary valve replacement. Cardiopulmonary exercise testing is used to assess exercise capacity in tetralogy of Fallot patients before pulmonary valve replacement. Read More

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November 2018
4 Reads

Risk Factors and Biomarkers of Poor Outcomes.

Circulation 2018 Nov;138(19):2116-2118

Heart Institute, Cincinnati Children's Hospital Medical Center, OH.

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November 2018
1 Read

Hospital Costs Related to Early Extubation after Infant Cardiac Surgery.

Ann Thorac Surg 2018 Nov 17. Epub 2018 Nov 17.

University of Michigan C.S. Mott Children's Hospital, 1540 E. Hospital Drive, Ann Arbor, MI 48109; Department of Pediatrics.

Background: The Pediatric Heart Network Collaborative Learning Study (PHN CLS) increased early extubation rates after infant Tetralogy of Fallot (TOF) and coarctation (CoA) repair across participating sites by implementing a clinical practice guideline (CPG). The impact of the CPG on hospital costs has not been studied.

Methods: PHN CLS clinical data were linked to cost data from Children's Hospital Association by matching on indirect identifiers. Read More

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November 2018
6 Reads

Tetralogy of Fallot With Right Aortic Arch and Retro-Aortic Innominate Vein.

Front Pediatr 2018 2;6:331. Epub 2018 Nov 2.

East Midlands Congenital Heart Center, Glenfield Hospital, Leicester, United Kingdom.

Right aortic arch (RAA) and retro-aortic innominate vein are rare vascular anomalies. Diagnosis of these anatomical variations can be achieved using fetal echocardiography, post-natal echocardiography, and computed tomography scan. RAA can form a vascular ring when associated with other vascular anomalies which may compress the trachea and/or esophagus. Read More

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November 2018
10 Reads

Shock to the heart: cardiac implantable devices' bad name in adults with tetralogy of Fallot.

Heart 2018 Nov 19. Epub 2018 Nov 19.

Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.

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November 2018
4 Reads

Neurocognitive profiles in adolescents and young adults with congenital heart disease.

Rev Port Cardiol 2018 Nov 16;37(11):923-931. Epub 2018 Nov 16.

Unidade de Investigação e Desenvolvimento Cardiovascular, Faculty of Medicine, University of Porto, Porto, Portugal; Centro de Referência de Cardiopatias Congénitas, Department of Pediatric Cardiology, Centro Hospitalar S. João, Porto, Portugal.

Introduction And Objectives: The objectives of this study were to assess the neuropsychological performance (NP) of adolescents and young adults with congenital heart disease (CHD), comparing them with a group of healthy controls, to determine whether there are different neurocognitive phenotypes in CHD, and to identify their relation to sociodemographic, neonatal, clinical and psychological adjustment variables.

Methods: A total of 217 CHD patients (116 male, aged 15.73±2. Read More

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November 2018
3 Reads

Outcome and Associated Findings in Individuals with Pre- and Postnatal Diagnosis of Tetralogy of Fallot (TOF) and Prediction of Early Postnatal Intervention.

Ultraschall Med 2018 Nov 19. Epub 2018 Nov 19.

Department of OB&GYN, Justus-Liebig-University and UKGM, Division of Prenatal Medicine, Giessen, Germany.

Purpose:  The aim of our retrospective evaluation was to compare the outcome of patients with prenatal and postnatal diagnosis of Tetralogy of Fallot (TOF) and to analyze prenatal echocardiographic parameters predicting intervention within 30 days postnatal.

Materials And Methods:  We evaluated 142 patients in our pediatric heart center and prenatal diagnosis center and prenatal practice Praenatal plus in Cologne between 01/08 - 06/16.

Results:  Within the prenatal diagnosis group, 6/74 fetuses (8. Read More

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November 2018
2 Reads

The aorta in repaired tetralogy of Fallot: A potential source of late danger?

Authors:
Joseph B Clark

J Thorac Cardiovasc Surg 2018 Dec 5;156(6):2250. Epub 2018 Oct 5.

Division of Pediatric Cardiac Surgery, Department of Pediatrics, Penn State Children's Hospital, Hershey, Pa. Electronic address:

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December 2018
1 Read

Reduced proximal aortic compliance and elevated wall shear stress after early repair of tetralogy of Fallot.

J Thorac Cardiovasc Surg 2018 Dec 21;156(6):2239-2249. Epub 2018 Sep 21.

Section of Congenital Heart Surgery, Heart Institute, Children's Hospital Colorado, University of Colorado Denver | Anschutz Medical Campus, Aurora, Colo.

Objective: Patients with tetralogy of Fallot are at risk for late aortic complications due to progressive aortic root dilation and decreased aortic compliance. Early repair normalizes aortic dimensions by preadolescence. It is not known if early repair normalizes aortic wall histology and compliance or reduces late aortic complications. Read More

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December 2018
1 Read

Reminder: Tetralogy of Fallot is not just a right-sided cardiac problem.

J Thorac Cardiovasc Surg 2018 Dec 5;156(6):2237-2238. Epub 2018 Oct 5.

Department of Pediatric Cardiothoracic Surgery, Arnold Palmer Hospital for Children, Orlando, Fla; Department of Surgery, University of Central Florida College of Medicine, Orlando, Fla. Electronic address:

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December 2018
1 Read

Echocardiography in Congenital Heart Disease.

Prog Cardiovasc Dis 2018 Nov 13. Epub 2018 Nov 13.

Department of Cardiovascular Disease, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, United States of America. Electronic address:

As the prevalence of adult congenital heart disease continues to grow secondary to advances in surgical and diagnostic techniques, it is important for a physician to supplement their examinations with non-invasive imaging techniques to assess their patients. Although a number of these patients have regular cardiology followup, some may be new patients that do not even know their cardiac history. Echocardiography has proven to be a useful tool for this purpose and its utility has expanded drastically with the development of better technology and newer techniques. Read More

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November 2018
5 Reads

Toward predictive modeling of catheter-based pulmonary valve replacement into native right ventricular outflow tracts.

Catheter Cardiovasc Interv 2018 Nov 15. Epub 2018 Nov 15.

Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Background: Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become a reality. However, predicting a secure, atraumatic implantation of a catheter-based device remains a significant challenge due to the complex and dynamic nature of the right ventricular outflow tract (RVOT). Read More

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November 2018
5 Reads

Comparison of Image Acquisition Techniques in Four-Dimensional Flow Cardiovascular MR on 3 Tesla in Volunteers and Tetralogy of Fallot Patients.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:1115-1118

Four-dimensional phase-contrast (PC) velocity-encoded flow magnetic resonance imaging (4D flow MRI) is a potentially valuable tool for studying cardiovascular hemodynamics for disease monitoring and/or treatment planning. In this study we compared the performance of two 4D flow MRI pulse sequences - echo-planar imaging (EPI) and segmented gradient-echo (turbo-field-echo or TFE on vendor's platform) - on a clinical 3T system in 6 human subjects including 3 patients with Tetralogy of Fallot (TOF). For aortic flow rate, the coefficients of variation (COV) between 2D and 4D EPI were 7. Read More

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July 2018
1 Read

Early outcomes of percutaneous pulmonary valve implantation using the Edwards SAPIEN 3 transcatheter heart valve system.

EuroIntervention 2018 Nov 13. Epub 2018 Nov 13.

Hôpital Marie Lannelongue, Le Plessis Robinson, France.

Aims: Multiple surgical revisions are often necessary in individuals with congenital heart defects affecting the RVOT or pulmonary valve. There are no multicentre data on the feasibility and safety of percutaneous pulmonary valve implantation using the SAPIEN 3 (S3) transcatheter heart valve.

Methods And Results: Pulmonic S3 is an observational registry of patients undergoing PPVI with the S3 valve across centres in Europe and Canada. Read More

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November 2018
2 Reads
3.770 Impact Factor

22q11.2 deletion detected by hybridization in Mexican patients with velocardiofacial syndrome-like features.

Colomb Med (Cali) 2018 Sep 30;49(3):219-222. Epub 2018 Sep 30.

División de Genética - CIBO. Instituto Mexicano del Seguro Social, Guadalajara, México.

Introduction: Deletion 22q11.2 occurs in 1:4,000-1:6,000 live births while 10p13p14 deletion is found in 1:200,000 newborns. Both deletions have similar clinical features such as congenital heart disease and immunological anomalies. Read More

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September 2018
1 Read

Optimal Pulmonary Valve Annulus Diameter for Annulus Preservation in Tetralogy of Fallot May Be Far Smaller Than Normal Annulus Size.

Semin Thorac Cardiovasc Surg 2018 Nov 5. Epub 2018 Nov 5.

Division of Pediatric Cardiac Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:

We hypothesized that optimal pulmonary valve annulus (PVA) diameter upon annulus preservation (AP) in tetralogy of Fallot (ToF) may be far smaller than the normal diameter. Retrospective review of the 61 consecutive patients who underwent ToF repair between January 2016 and September 2017 was performed. Median age, body weight, and median PVA (Z) at repair were 166 days (interquartile range, IQR, 141-182 days), 7. Read More

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November 2018
4 Reads

A Rare Case of Tetralogy of Fallot Associated with Pulmonary Artery Sling.

Authors:
Seha Ahn Cheul Lee

Korean J Thorac Cardiovasc Surg 2018 Oct 5;51(5):360-362. Epub 2018 Oct 5.

Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea.

Pulmonary artery sling is a rare congenital cardiac anomaly, in which the left pulmonary artery originates from the right pulmonary artery and courses leftward between the trachea and the esophagus. Tetralogy of Fallot associated with pulmonary artery sling is even rarer, and only a few cases have been reported in the literature. We present a case of tetralogy of Fallot associated with pulmonary artery sling that was repaired successfully. Read More

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October 2018
1 Read

Tetralogy of Fallot in the Current Era.

Semin Thorac Cardiovasc Surg 2018 Nov 2. Epub 2018 Nov 2.

Department of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.

Only few studies have reported long-term outcome of the transatrial-transpulmonary approach in the current era of management of tetralogy of Fallot (ToF). We investigated 15-year outcome of correction via a transatrial-transpulmonary approach in a large cohort of successive patients operated in the 21st century. All infant ToF patients undergoing transatrial-transpulmonary ToF correction between 2000 and 2015 were included (N = 177, 106 male, median follow-up 7. Read More

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November 2018
6 Reads

Eligibility for subcutaneous implantable cardioverter defibrillators in the adult congenital heart disease population.

Pacing Clin Electrophysiol 2018 Nov 5. Epub 2018 Nov 5.

Department of Cardiology, Queen Elizabeth Hospital, Birmingham, United Kingdom.

Background: Patients with adult congenital heart disease (ACHD) have an increased risk of arrhythmic and sudden cardiac death. The subcutaneous implantable cardioverter defibrillator (S-ICD) provides a potentially safer alternative to transvenous ICDs in ACHD. Suitability for S-ICD depends on the surface electrocardiogram (ECG), which is often abnormal in ACHD patients. Read More

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November 2018
4 Reads

Sustainability of infant cardiac surgery early extubation practices after implementation and study.

Ann Thorac Surg 2018 Oct 31. Epub 2018 Oct 31.

Emory University, Atlanta, GA, Department of Pediatrics and Sibley Heart Center.

Background: The Pediatric Heart Network Collaborative Learning Study (PHN CLS) successfully changed practice at 4 hospitals to increase the rate of early extubation within 6 hours after infant heart surgery. It is unknown whether this practice continued after study completion.

Methods: We linked the PHN CLS dataset to the Pediatric Cardiac Critical Care Consortium registry to compare outcomes at 4 active hospitals between the study period (post-CPG) and the first year after study completion (follow-up) after a 3-month washout. Read More

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October 2018
9 Reads

Tetralogy of fallot with pulmonary atresia and aorto-pulmonary window: Or is it truncus arteriosus?

J Cardiovasc Comput Tomogr 2018 Oct 26. Epub 2018 Oct 26.

Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.

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October 2018
1 Read

Echocardiographic MRI: an innovative fusion of functional and anatomic assessment strategy for CHD.

Cardiol Young 2018 Oct 31:1-2. Epub 2018 Oct 31.

Children's Hospital of Orange County,Pediatric Heart Institute,Orange,CA 92868,USA.

We present a pilot case using an innovative fusion of echocardiogram and MRI achieved with a MATLAB-based imaging programme to explore the feasibility of this imaging strategy in the functional and anatomic assessment of a patient with repaired tetralogy of Fallot requiring pulmonary valve intervention. Echocardiogram and MRI neutralises the disadvantages and limitations of each individual imaging modality and yields important anatomic and haemodynamic information crucial to the treatment decision-making process. Future image fusion strategies can apply to three-dimensional images and image-directed therapy for CHD. Read More

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October 2018
7 Reads

Cardiac implantable electronic devices in adults with tetralogy of Fallot.

Heart 2018 Oct 30. Epub 2018 Oct 30.

Department of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, Minnesota, USA.

Background: Tachyarrhythmias and bradyarrhythmias affect 20%-50% of adult patients with tetralogy of Fallot (TOF) and some of these patients will require cardiac implantable electronic devices (CIED) such as pacemaker and/or internal cardioverter defibrillator.

Methods: The Mayo Adult Congenital Heart Disease database was queried for patients with repaired TOF and history of CIED implantation, 1990-2017. The study objectives were: (1) determine the occurrence of device-related complications defined as lead failure, lead recall, device infection and lead thrombus; and (2) determine the occurrence and risk factors for defibrillator shock. Read More

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October 2018
2 Reads
5.590 Impact Factor

Experience participating in the American College of Cardiology Quality NetworkTM: paediatric and adult congenital cardiology collaborative quality improvement.

Cardiol Young 2018 Oct 30:1-8. Epub 2018 Oct 30.

Department of Cardiology,Boston Children's Hospital,Harvard Medical School,Boston,MA,USA.

Background: The American College of Cardiology Quality Network enables national benchmarking and collaborative quality improvement through vetted metrics. We describe here our initial experience with the Quality Network.

Methods: Quarterly data for metrics pertaining to chest pain, Kawasaki disease, tetralogy of Fallot, elevated body mass index, and others were shared with the collaboratives for benchmarking. Read More

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October 2018
5 Reads

Long-term follow-up in adults after tetralogy of Fallot repair.

Cardiovasc Ultrasound 2018 Oct 29;16(1):28. Epub 2018 Oct 29.

Department of Cardiac and Vascular Disease, Collegium Medicum, Jagiellonian University, John Paul II Hospital, Krakow, Poland.

Background: Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease and the population of ToF repair survivors is growing rapidly. Adults with repaired ToF develop late complications. The aim of this study was to describe and analyze long-term follow-up of patients with repaired ToF. Read More

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October 2018
11 Reads

The change of QRS duration after pulmonary valve replacement in patients with repaired tetralogy of Fallot and pulmonary regurgitation.

Korean J Pediatr 2018 Nov 24;61(11):362-365. Epub 2018 Oct 24.

Division of Pediatric Cardiology, Department of Pediatrics, Kyungpook National University Children's Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

Purpose: This study aimed to analyze changes in QRS duration and cardiothoracic ratio (CTR) following pulmonary valve replacement (PVR) in patients with tetralogy of Fallot (TOF).

Methods: Children and adolescents who had previously undergone total repair for TOF (n=67; median age, 16 years) who required elective PVR for pulmonary regurgitation and/or right ventricular out tract obstruction were included in this study. The QRS duration and CTR were measured pre- and postoperatively and postoperative changes were evaluated. Read More

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November 2018
4 Reads

Intentional Fracture of Bioprosthetic Valve Frames in Patients Undergoing Valve-in-Valve Transcatheter Pulmonary Valve Replacement.

Circ Cardiovasc Interv 2018 Aug;11(8):e006453

Departments of Pediatrics and Cardiothoracic Surgery, Lucile Packard Children's Hospital Heart Center, Stanford University School of Medicine, Palo Alto, CA (D.B.M.).

Background: Percutaneous transcatheter pulmonary valve replacement (TPVR) has good clinical and hemodynamic outcomes in treating dysfunctional bioprosthetic valves (BPV) in the pulmonary position. Valve-in-valve therapy can further decrease the inner diameter (ID), potentially resulting in patient-prosthesis mismatch in patients with smaller BPVs.

Methods And Results: To evaluate feasibility and outcomes of intentional BPV fracture to enlarge the pulmonary valve orifice with TPVR, 37 patients from 13 centers who underwent TPVR with intended BPV fracture were evaluated. Read More

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August 2018
13 Reads

Arrhythmogenic Remodeling of the Left Ventricle in a Porcine Model of Repaired Tetralogy of Fallot.

Circ Arrhythm Electrophysiol 2018 Oct;11(10):e006059

IHU LIRYC, L'Institut de Rythmologie et Modélisation Cardiaque, Fondation Bordeaux Université, Pessac, France (V.D., D.B., F.R., S.H.G., M.C., S.C., D.E., B.Q., H.C., M.H., C.R., P.B., J.-B.T., O.B.).

Background: Ventricular arrhythmias are frequent in patients with repaired tetralogy of Fallot (rTOF), but their origin and underlying mechanisms remain unclear. In this study, the involvement of left ventricular (LV) electrical and structural remodeling was assessed in an animal model mimicking rTOF sequelae.

Methods: Piglets underwent a tetralogy of Fallot repair-like surgery (n=6) or were sham operated (Sham, n=5). Read More

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October 2018
1 Read

Differences in Right Ventricular Physiologic Response to Chronic Volume Load in Patients with Repaired Pulmonary Atresia Intact Ventricular Septum/Critical Pulmonary Stenosis Versus Tetralogy of Fallot.

Pediatr Cardiol 2018 Oct 23. Epub 2018 Oct 23.

Division of Pediatric Cardiology, Children's Hospital Los Angeles, 4650 Sunset Blvd., Mailstop #34, Los Angeles, CA, 90027, USA.

Background: Patients with pulmonary atresia with intact ventricular septum and critical pulmonary stenosis (PAIVS/CPS) have wide variation in right ventricle (RV) size, systolic function, and diastolic function at birth. Establishment of antegrade pulmonary blood flow creates the potential for RV dilation from chronic pulmonary insufficiency. Future surgical decisions are based on RV size and function, largely supported by longitudinal studies of patients with Tetralogy of Fallot (TOF). Read More

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October 2018
8 Reads

CEREBRAL BLOOD FLOW AND PREDICTORS OF WHITE MATTER LESIONS IN ADULTS WITH TETRALOGY OF FALLOT.

Proc IEEE Int Symp Biomed Imaging 2018 Apr 24;2018:1309-1312. Epub 2018 May 24.

Division of Cardiology, Children's Hospital Los Angeles, CA, USA.

Long-term outcomes for Tetralogy of Fallot (TOF) have improved dramatically in recent years, but survivors are still afflicted by cerebral damage. In this paper, we characterized the prevalence and predictors of cerebral silent infarction (SCI) and their relationship to cerebral blood flow (CBF) in 46 adult TOF patients. We calculated both whole brain and regional CBF using 2D arterial spin labeling (ASL) images, and investigated the spatial overlap between voxel-wise CBF values and white matter hyperintensities (WMHs) identified from T2-FLAIR images. Read More

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April 2018
2 Reads

Novel Point Mutations in the Gene in Pediatric Patients with Non-Familial Congenital Heart Disease.

Medicina (Kaunas) 2018 Jun 19;54(3). Epub 2018 Jun 19.

Department of Cardiac Surgery, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd 8915818411, Iran.

: Congenital heart disease (CHD) is the most common birth abnormality in the structure or function of the heart that affects approximately 1% of all newborns. Despite its prevalence and clinical importance, the etiology of CHD remains mainly unknown. Somatic and germline mutations in cardiac specific transcription factor genes have been identified as the factors responsible for various forms of CHD, particularly ventricular septal defects (VSDs), tetralogy of Fallot (TOF), and atrial septal defects (ASDs). Read More

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June 2018
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