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G Chir 2019 Jan-Feb;40(1):54-57

Discovery of an apparent scrotal mass is a non common entity in neonates. Testicular torsion is rare in newborn infants and is an urologic emergency that requires emergency surgical management. We present a rare case of testicular torsion in a neonate. Read More

Andrologia 2019 Feb 11:e13243. Epub 2019 Feb 11.

Faculty of Veterinary Medicine, Department of Clinical Sciences, Urmia Branch, Islamic Azad University, Urmia, Iran.

This study is aimed to analyse the cross-link between cyclin D1, cdk-4, p21, PCNA and DNA damage during different periods of reperfusion following experimental torsion in rats. Thirty mature male Wistar rats (N = 6) were used. Following 4 hr from torsion induction, the reperfusion was induced. Read More

SAGE Open Med Case Rep 2019 16;7:2050313X18823451. Epub 2019 Jan 16.

Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.

Testicular vasculitis is uncommon and can be easily misdiagnosed. Early identification and treatment are essential for patient care. A 63-year-old man, presenting with testicular pain and swelling, had been treated with antibiotics for weeks. Read More

Cir Pediatr 2019 Jan 21;32(1):17-21. Epub 2019 Jan 21.

UGC Cirugía Pediátrica. Hospital Universitario Reina Sofía. Córdoba.

Aim: To present our experience in pediatric patients with testicular torsion (TT) treated by manual detorsion (MD).

Patients And Methods: Retrospective analysis of patients treated by MD in a 10-year period in a single center. Description of symptoms, detorsion technique, follow-up and complications. Read More

J Pediatr Urol 2018 Dec 21. Epub 2018 Dec 21.

Surgical Outcomes Center for Kids, Monroe Carell Jr. Children's Hospital at Vanderbilt, 2200 Children's Way Nashville, TN 37232, USA; Division of Pediatric Urology, Monroe Carell Jr. Children's Hospital at Vanderbilt, 2200 Children's Way, Suite 4102, Nashville, TN 37232-9820, USA.

Introduction: Testicular torsion is a urological emergency; as the testicular salvage rate decreases with time, prompt intervention is required to restore the blood flow. Interhospital transfers and ultrasound examinations, while clinically essential to proper treatment and diagnosis, may adversely affect outcomes by delaying surgical intervention. Patients transferred to another institution for treatment of testicular torsion may experience a further time delay by undergoing two ultrasound examinations: one at the initial admitting institution and one at the receiving institution. Read More

BMC Urol 2019 Jan 31;19(1):14. Epub 2019 Jan 31.

Department of Urology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

Background: An acute scrotal hematoma, secondary to a spontaneous rupture of a varicocele is still a rare presentation in daily practice. However, multiple case reports have been reported. Sudden increase in abdominal pressure, resulting to an increased venous pressure can lead to a rupture of the varicocele. Read More

Sex Dev 2019 Feb 1. Epub 2019 Feb 1.

Cerebral palsy is a rare condition following injury of the developing brain and including nonprogressive neurological disorders, spasticity, intellectual impairment and others. Boys with cerebral palsy have a high incidence of undescended testis. Although the motives for treatment (infertility, cancer prevention, psychological aspects, testicular torsion) are not different in boys without neurological impairment, the decision-making process in boys with cerebral palsy is very difficult. Read More

Urology 2019 Jan 3. Epub 2019 Jan 3.

Department of Urology, School of Medicine, Urology Institute, University Hospitals Cleveland Medical Centre, Cleveland, OH. Electronic address:

We herein report an unusual case of testicular torsion a decade after orchiopexy. An occurrence of postorchiopexy testicular torsion is an exceedingly rare event, infrequently reported in literature. Previously placed anchoring sutures in the inferior pole resulted in a "hammock" testicular torsion, resulting in twisting of cord with involvement of the sutures themselves. Read More

Scand J Urol 2019 Jan 2:1-3. Epub 2019 Jan 2.

a Urology Department , Herlev-Gentofte Hospital , Herlev , 2730 , Denmark.

Objectives: To evaluate the role of scrotal ultrasound in the follow-up after epididymitis for underlying serious testicular pathologies, which could be overseen in the acute phase.

Methods: Retrospective chart reviews were performed for patients diagnosed with acute epididymitis at Herlev-Gentofte Hospital between 2006 and 2013. Patients were included if they had received the diagnosis after a clinical evaluation in the emergency department and had subsequently undergone antibiotic treatment and a follow-up scrotal ultrasound at a later date. Read More

World J Mens Health 2019 Jan;37(1):99-104

Department of Urology, College of Medicine, Yeungnam University, Daegu, Korea.

Purpose: Though prompt diagnosis to minimize symptom duration (SD) is highly associated with organ salvage in cases of testicular torsion (TT), SD is subjective and hard to determine. We thus investigated the clinical implications of systemic inflammatory responses (SIRs) as potential surrogates of SD to improve testis survival.

Materials And Methods: Sixty men with TT that underwent immediate operation among orchiectomy and orchiopexy following a visit to a single emergency department were retrospectively enrolled. Read More

Res Rep Urol 2018 5;10:241-249. Epub 2018 Dec 5.

Department of Pediatric Surgery, Hamad General Hospital, Doha, Qatar,

Purpose: Testicular torsion (TT) represents a clinical challenge that needs emergency surgical assessment. It is common to have negative scrotal exploration due to confounding symptoms and signs which makes it sometimes difficult to differentiate from similar surgical emergencies that do not warrant surgery. At the same time, several occasions of misdiagnoses or late interventions occur with devastating effects. Read More

Stem Cells Transl Med 2018 Dec 19. Epub 2018 Dec 19.

Department of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.

Torsion-detorsion (T/D)-induced testicular injury may lead to male subfertility and even infertility. Stem cell therapy provides an alternative to attenuate testicular injury and promote spermatogenesis. Adipose-derived stromal vascular fraction (SVF) can be acquired conveniently without in vitro expansion, which may avoid the potential risks of microbial contamination, xenogenic nutritional sources, etc. Read More

Arch Esp Urol 2018 Dec;71(10):840-849

Laboratorio de Andrología, Microbióloga y Química Clínica. Instituto Nacional de Perinatología. Isidro Espinosa de los Reyes. Ciudad de México. México.

Testicular microlithiasis (TM) is an uncommonurologic condition incidentally diagnosed byscrotal ultrasound. It has been associated with differentdiseases, such as Klinefelter`s syndrome, testicular atrophy,cryptorchidism, testicular torsion, and infertility.However, it can also present in healthy males that haveno associated risk factors. Read More

Zhonghua Yi Xue Za Zhi 2018 Dec;98(46):3729-3731

Front Pediatr 2018 20;6:318. Epub 2018 Nov 20.

Pediatric Surgery, Hamad Medical Corporation, Doha, Qatar.

Perinatal testicular torsion is a relatively rare event that remains unidentified in many situations and managed only after an avoidable delay of time. Its current management approaches include watchful observation, delayed contralateral orchiopexy, and emergent contralateral orchiopexy. On the other hand, bilateral torsion is now being more frequently reported. Read More

Saudi Med J 2018 Dec;39(12):1232-1237

Division of Pediatric Surgery, Department of Surgery, College of Medicine, Taibah University, Almadinah Al-munawarah, Kingdom of Saudi Arabia. E-mail.

Objectives: To review and compare clinical practice and experience among pediatric surgeons (PS) and pediatric urologists (PU) for the management of testicular torsion (TT) in the Kingdom of Saudi Arabia (KSA).

Methods: This was a cross-sectional study conducted between August 2016 and November 2017, among all PU and PS involved in the management of suspected TT in KSA. A questionnaire was distributed to participants through the Survs. Read More

J Pediatr Urol 2018 Sep 24. Epub 2018 Sep 24.

Division of Urology, Beirut, Lebanon. Electronic address:

Background: Testicular torsion is a surgical emergency mainly affecting adolescent boys, with a relatively high rate of missed torsion and testicular loss secondary to delay in prompt diagnosis and surgical intervention. With ischemic reperfusion injury as its underlying culprit, testicular torsion may respond favorably to remote ischemic conditioning (RIC) where a non-privileged site (e.g. Read More

Rev Int Androl 2018 Nov 23. Epub 2018 Nov 23.

Department of Pharmacology, Faculty of Medicine, Erzincan University Erzincan, Turkey. Electronic address:

Introduction And Objectives: Testicular ischemia/reperfusion (I/R) injury develops after torsion and following detorsion of the testis. Reactive oxygen species were produced and oxidative damage begins to occur due to I/R process. Nimesulide, which is a specific cyclooxygenase-2 inhibitor drug, have antioxidant, antiinflammatory, analgesics and antipyretic effects. Read More

Int J Surg Case Rep 2018 13;53:345-347. Epub 2018 Nov 13.

Urology Department, Ibn El Jazzar Teaching Hospital, Kairouan, Tunisia.

Introduction: Polyorchidism, defined as the presence of more than two testicles, is a rare congenital abnormality of the male genital tract. There is no consensus regarding the management of supranumerary testis (SNT) due to its rareness. To the best of our knowledge, this is the first report of leiomyoma in SNT. Read More

J Int Med Res 2019 Feb 19;47(2):730-737. Epub 2018 Nov 19.

Department of Urology, Tepecik Training and Research Hospital, Izmir, Turkey.

Objective: To investigate the use of hematological parameters in the differential diagnosis of testis torsion and epididymo-orchitis, and to determine the predictive value of these parameters in the diagnosis of testis torsion.

Methods: This study retrospectively reviewed the medical data of patients who presented to our institute with the complaint of acute scrotal pain. Eighty-five patients who had undergone orchiectomy or surgical detorsion due to testis torsion and 72 patients with epididymo-orchitis were included in the study. Read More

Clin Pract Cases Emerg Med 2018 Nov 18;2(4):283-285. Epub 2018 Oct 18.

Madigan Army Medical Center, Department of Emergency Medicine, Tacoma, Washington.

In this article, we present two medicolegal cases illustrating medical and diagnostic pitfalls that can lead to litigation for missed testicular torsion. Testicular torsion (TT) is a urologic emergency with potentially devastating consequences and costs, for providers and patients alike. TT occurs in approximately 4. Read More

J Pediatr Surg 2019 Mar 22;54(3):608-611. Epub 2018 Oct 22.

Department of Surgery, Division of Pediatric Surgery, Hospital Quironsalud Sur, Madrid, Spain. Electronic address:

Transverse testicular ectopia is a rare condition in which both testicles occupy a single hemiscrotum. The aberrant positioning may lead to vascular compromise or impaired temperature regulation, which elevate the risks for torsion, infertility and testicular cancer. Definitive therapy consists of orchiectomy or orchiopexy. Read More

J Pediatr Urol 2018 Dec 5;14(6):503-509. Epub 2018 Oct 5.

Royal Hospital for Children, 1345 Govan Road, Glasgow, G51 4TF, United Kingdom.

Introduction: Reported testicular loss rates following paediatric testicular torsion often reflect the surgical decision-making process, rather than long-term survival of the testes.

Objectives: We aim to perform systematic analysis and meta-analysis to investigate testicular salvage rates and to assess predictors of long-term viability.

Study Design: Systematic review according to PRISMA guidelines was performed to investigate immediate and long-term (>12 months) testicular loss rates following torsion in the paediatric population. Read More

Reprod Biol 2018 Dec 2;18(4):361-367. Epub 2018 Nov 2.

Department of Histology and Embryology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.

Varicocele is one of the main and surgically repairable causes of male infertility, which arises from dilatation and torsion of the testicular veins in the plexus pampiniformis. In this study, we examined semen samples from 40 patients diagnosed with varicocele between the ages of 15 and 30 years, according to WHO criteria (pre-operatively, and at 3, 6, and 12 months post-operatively). The mean spermatozoa concentration was found to be 45. Read More

Turk J Urol 2018 Nov;44(6):511-514

Department of Urology, Shahid Bahonar Hospital, Kerman University of Medical Sciences (KMU), Kerman, Iran.

Perinatal testicular torsion is a rare emergency in a neonate that prompts immediate attention. Bilateral testicular torsion is extremely rare. We report a case of bilateral torsion that presented with unilateral scrotal swelling but significant atrophy and dark discoloration of the contralateral testis that was secondary to asynchronous prenatal torsion. Read More

Urol Int 2019 26;102(1):113-117. Epub 2018 Oct 26.

Department of Pediatric Surgery, Woman's and Children's Hospital, Shenzhen University and Pingshan District, Shenzhen, China.

Objective: To investigate the clinical features, diagnosis, treatment and prognosis of children with cryptorchidism complicated by testicular torsion.

Methods: The clinical data of 6 children with cryptorchidism complicated by testicular torsion admitted to our hospital from December 2000 to December 2016 were analyzed retrospectively.

Results: All 6 children were diagnosed with cryptorchidism by surgery, their age was from 12 days up to 11 years, and the average time between onset of symptoms and diagnosis was 20. Read More

BMJ Case Rep 2018 Oct 27;2018. Epub 2018 Oct 27.

Department of Pediatric Surgery, Dayton Children's Hospital/Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA.

Testicular torsion and acute incarcerated inguinal hernia are both common surgical emergencies in the paediatric population. We present the unusual case of a 16-year-old adolescent boy who presented with both of these conditions concurrently. He had a history of a right inguinal hernia, but ultrasound confirmed a testicular torsion and we employed manual detorsion in the emergency department prior to taking him to the operating room. Read More

Nucl Med Mol Imaging 2018 Oct 2;52(5):377-379. Epub 2018 Jul 2.

1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Sector -12, Chandigarh, 160012 India.

Testicular torsion is a common differential diagnosis of acute scrotal pain along with acute epididymo-orchitis, which may lead to testicular non-viability. Doppler ultrasound and testicular scintigraphy are two routinely used modalities for the assessment of testicular viability. However, in some cases, these investigations may prove inadequate in differentiating between the two entities with widely differing management. Read More

Biomed Res Int 2018 20;2018:9808152. Epub 2018 Sep 20.

Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.

Background: Management of chronic idiopathic testicular pain may be difficult because of problems identifying the causes. We evaluated "AUTOKLAV", a novel endourological nephrolithotomy device to diagnose and treat chronic idiopathic testicular pain.

Methods: We divided 103 patients to either scrotoscopy group (SG, n = 64) or open exploration group (OEG, n = 39) between September 2014 and March 2017 at Zhongnan Hospital. Read More

Life Sci 2018 Nov 13;213:142-148. Epub 2018 Oct 13.

Department of Urology, Affiliated Haikou Hospital of Xiangya School of Medicine, Central South University, Haikou 570208, Hainan Province, China; Haikou Center for Medical Synchrotron Radiation Research, Haikou People's Hospital, Haikou 570208, Hainan Province, China. Electronic address:

Aims: Testicular ischemia-reperfusion (IR) injury is the primary pathophysiological consequence of testicular torsion. Low-energy shock wave (LESW) is an effective treatment for certain diseases. The present study investigated whether LESW could improve on testicular IR injury in rats and examined the involved mechanism. Read More

Asian J Androl 2018 Oct 12. Epub 2018 Oct 12.

The Institute for the 3Rs & Department of Laboratory Animal Medicine, College of Veterinary Medicine and Veterinary Science Research Institute, Konkuk University, Seoul 05029, Korea.

Testicular torsion, a common urologic emergency, is primarily caused by ischemia/reperfusion (I/R) injury of the testis. Nitric oxide (NO)-derived from nitrite (NO) has been reported to have prominent therapeutic effects on I/R injury in the heart, liver, and brain; however, its effects on testicular I/R injury have not been evaluated. This study, therefore, investigated whether NO from NO is beneficial in a rat model of testicular I/R injury which eventually results in impaired spermatogenesis. Read More

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:106

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

Rev Int Androl 2018 Jul - Sep;16(3):87-94. Epub 2017 Jun 7.

Department of Biochemistry, Faculty of Medicine, Atatürk University, Erzincan, Turkey.

Background: It has been reported in the literature that proinflammatory interleukin-1 beta (IL-1β) is increased in cases of testicular ischemia reperfusion (I/R) damage. This information suggests that anakinra, an IL-1β antagonist, may be effective in testicular I/R damage.

Objective: In our study, we investigated the effect of anakinra on testicular I/R damage induced in rats with torsion/detorsion. Read More

Rev Urol 2018 ;20(2):104-106

Department of Pediatric Urology, NYU Langone Hospital-Brooklyn Brooklyn, NY.

J Pediatr Urol 2018 Oct 23;14(5):402-406. Epub 2018 Aug 23.

Department of Urology, Osaka Women's and Children's Hospital, Osaka, Japan.

Introduction: Torsion of an undescended testis (UDT) associated with cerebral palsy (CP) and neuromuscular disease (NMD) is an uncommon condition that is not well recognized by primary care physicians or healthcare providers.

Objective: The objective of this study was to highlight the clinical importance of torsion of a UDT in children with CP and NMD.

Materials And Methods: Eleven children with testicular torsion of a UDT operated on at the study institute between 1991 and 2015 were identified. Read More

Urol J 2018 Sep 11. Epub 2018 Sep 11.

Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad -IRAN.

Purpose: The present study was conducted to investigate the influence of hemicastration and age at hemicastration on the subsequent contralateral testis.

Materials And Methods: 64 Wistar-derived male rats divided randomly in 4 groups. Group 1 named immature intervention, group 2 immature control, group 3 mature intervention and group 4mature control. Read More

J Pediatr Urol 2018 Aug 17. Epub 2018 Aug 17.

Nationwide Children's Hospital, Department of Anesthesiology, 700 Children's Drive, Columbus, OH 43205, USA.

Introduction: Increasing concerns regarding potential negative effects of early use of inhalational and intravenous anesthetics on neurocognitive development have led to a growing interest in alternative forms of anesthesia in infants. The study institution's outcomes with spinal anesthesia (SA) for urologic surgery in infants aged less than 90 days are reported and their outcomes with a matched cohort of patients who underwent general anesthesia (GA) are compared.

Methods: This is a retrospective single-center analysis. Read More

Urol J 2018 Nov 17;15(6):387-396. Epub 2018 Nov 17.

Gaziosmanpaşa University, Faculty of Medicine, Department of Urology, Tokat 60100, Turkey.

Purpose: The aim of the present study was to show the protective effect of pulsed magnetic field (PMF) application and melatonin administration on damage in testis in a one-sided torsion detorsion induced rat model using testicular scintigraphy with 99mTc pertechnetate, PET/CT with 18F-FDG and histopathological methods.

Materials And Methods: Sixty male rats were used in the study; 30 rats were randomly divided into five groups for one day applications of sham control, torsion, melatonin, pulsed magnetic field (PMF) and melatonin plus PMF. Similarly, for one week group, the other 30 rats were divided into the same five group (n=6), but the animals were sacrificed after one week. Read More

Ann Med Surg (Lond) 2018 Sep 20;33:47-49. Epub 2018 Aug 20.

Department of Paediatric Surgery, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.

Introduction: A fast surgical treatment is the gold standard when a testicular torsion is diagnosed.However, an early diagnosis of torsion may not be feasible in case of torsion associated with undescended testis in the patients affected by cerebropalsy.

Case Presentation: A Bolivian 16 year old male with acquired cerebropalsy and spastic neuromuscular disease was admitted to our Institute for a right inguinal swelling observed by the father in the morning. Read More

Andrologia 2018 Dec 29;50(10):e13134. Epub 2018 Aug 29.

Department of Urology, University of Health Sciences, Haydarpasa Numune Research & Training Hospital, Istanbul, Turkey.

Testicular torsion is a surgical emergency and the testicular salvage rate through surgical detorsion ranges from 42% to 88%. However, it is not known to what extent spermatogenic function is preserved in these testes. The purpose of the study was to demonstrate the prognostic value of thiol/disulphide homeostasis in rats for testicular ischaemia and ischaemia-reperfusion injury during early and late stages. Read More

Zhonghua Nan Ke Xue 2018 Janurary;24(1):55-58

Department of Urology, Xuzhou Hospital Affiliated to Southeast University School of Medicine, Xuzhou, Jiangsu 221009, China.

Objective: To investigate the clinical effect of plaque excision plus autologous perididymal patch grafting in the treatment of Peyronie's disease.

Methods: This study included 10 patients with Peyronie's disease received in our Department of Urology between January 2013 and December 2015, who had failed to respond to over 12 months of expectant drug therapy and remained stable for more than 6 months, none able to perform sexual intercourse due to penile curvature (>60°). All the patients underwent plaque excision plus autologous perididymal patch grafting. Read More

Int Braz J Urol 2018 Sep-Oct;44(5):1005-1013

Department of Urology, Fatih Sultan Mehmet Research & Training Hospital, University of Health Sciences, Istanbul, Turkey.

Objectives: To evaluate protective effects of darbepoetin and tadalafil against ischemiareperfusion injury in ipsilateral and contralateral testicle.

Materials And Methods: Thirty 3-month-old adult male Wistar-Albino rats were randomly divided into 5 groups (A-E). Sham operation was performed in the first group. Read More

Urol Case Rep 2018 Nov 4;21:1-2. Epub 2018 Aug 4.

Urology Department, Medical University of Sfax, Habib Bourguiba Hospital, Avenue Majida-Boulila, 3029 Sfax, Tunisia.

Emerg Med J 2018 Sep;35(9):574-575

Manchester Royal Infirmary, Manchester, UK.

A shortcut review of the literature was carried out to establish whether the Testicular Workup for Ischemia and Suspected Torsion (TWIST) score was reliable and accurate enough to rule out testicular torsion in the paediatric population.Four papers were found to be relevant to the clinical question following the below-described search strategies. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of those best papers are tabulated. Read More

J Pediatr Surg 2018 Aug 8. Epub 2018 Aug 8.

Department of Pediatric Surgery, NYU-Winthrop Hospital, Mineola, New York, USA; Department of Pediatric Surgery, Montefiore Medical Center, Bronx, New York, USA. Electronic address:

Objective: This meta-analysis seeks to discern the optimal management strategy in neonatal testicular torsion (NTT).

Methods: Reviewed all English-language articles published between 2005 and 2015 in Medline/Pubmed that had a defined diagnosis of NTT within the first thirty days of life, and discussed specific surgical and nonsurgical management. Exclusion criteria were non-English literature, case reports, case studies, and failure to clearly describe the management of NTT. Read More

Front Endocrinol (Lausanne) 2018 26;9:425. Epub 2018 Jul 26.

Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.

Cryptorchidism is one of the most frequent congenital birth defects in male children and is present in 2-4% of full-term male births. It has several possible health effects including reduced fertility, increased risk for testicular neoplasia, testicular torsion, and psychological consequences. Cryptorchidism is often diagnosed as comorbid; copresent with other diseases. Read More

Urol J 2018 Aug 9. Epub 2018 Aug 9.

Women and Child Hospital, Azienda Ospedaliera Universitaria Integrata, University Of Verona, Italy.

Introduction: Testicular torsion is an emergency at any age; the aim of this study is to evaluate the role of mean platelet volume to assess the viability of the testes before surgeryMaterials and methods: We retrospectively analysed the medical records of consecutive patients who underwent surgical exploration for acute scrotal pathology between January 2014 and December 2016 in our institution.Patients were divided into two groups (detorsion of testes and orchyectomy); a third group was created as control group. All patients underwent blood exam before surgery; inclusion and exclusion criteria were created. Read More

Urol Ann 2018 Jul-Sep;10(3):345-346

Department of Urology, Sohar Hospital, Ministry of Health, Sultanate of Oman, Sohar, Oman.

J Pediatr Urol 2018 Oct 21;14(5):394-401. Epub 2018 Jul 21.

Department of Urology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Testicular torsion remains the most frequent cause of testicular ischemia, especially in adolescents and young adults. Timely diagnosis and intervention are keys to saving the affected testicle. This review presents current trends in the diagnosis and treatment of torsion, potential pitfalls and consequent outcomes. Read More

Life Sci 2018 Sep 1;209:57-62. Epub 2018 Aug 1.

Department of Pharmacology, Faculty of Medicine, Minia University, 61511 Minia, Egypt.

Aims: Torsion of the spermatic cord is a common urologic emergency and can lead to testicular necrosis and infertility. Diacerein (DIA) is interleukin-1b (IL-1b) blocker which has a protective role against myocardial ischemia-reperfusion, however, to-date this role has not been investigated in testicular ischemia- reperfusion (TIR). We aimed to investigate the role and mechanism of action of DIA in induced TIR. Read More